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Challenges in diagnosing common skin conditions among medical students from the United States in Panama 在巴拿马的美国医科学生在诊断常见皮肤病方面遇到的挑战。
Pub Date : 2024-05-18 DOI: 10.1016/j.jdin.2024.05.003
Natalia Correa BS , Olnita Martini MS , Alexa Carboni BS , Michael Miller MPH , Mark Wardle DO
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引用次数: 0
Differences in attitudes toward aging skin between skin of color and non-skin of color consumers: A cross-sectional survey study 有色人种和非有色人种消费者对皮肤老化的态度差异:一项横断面调查研究
Pub Date : 2024-05-17 DOI: 10.1016/j.jdin.2024.05.002
Lynna J. Yang BA, Roopal V. Kundu MD
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引用次数: 0
Low rate of seroconversion analyzing QuantiFERON TB-gold testing in patients with psoriasis and hidradenitis suppurativa taking biologic therapy at an academic center in New York City 纽约市一家学术中心对接受生物疗法的银屑病和化脓性扁平苔藓患者进行 QuantiFERON TB-gold 检测后发现血清转换率较低
Pub Date : 2024-05-10 DOI: 10.1016/j.jdin.2024.04.004
Apostolos Katsiaunis BS , Jade Conway BA , Debra D'Angelo MS , Shari R. Lipner MD, PhD
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引用次数: 0
Incidence and mortality trends of primary cutaneous melanoma: A 50-year Rochester Epidemiologic Project study 原发性皮肤黑色素瘤的发病率和死亡率趋势:为期 50 年的罗切斯特流行病学项目研究
Pub Date : 2024-05-10 DOI: 10.1016/j.jdin.2024.04.010
Jacob P. Reinhart MD , Elliott H. Campbell MD , Sydney L. Proffer MD, MS , Olivia M. Crum MD , Austin Todd MS , Lawrence E. Gibson MD , Jerry D. Brewer MD, MS , Addison M. Demer MD

Background

National cancer reporting-based registry data, although robust, lacks granularity for incidence trends. Expert opinion remains conflicted regarding the possibility of melanoma overdiagnosis in the context of rising incidence without a corresponding rise in mortality.

Objective

To characterize 10- and 50-year trends in melanoma incidence and mortality.

Methods

Multicenter, population-based epidemiologic study utilizing the Rochester Epidemiology Project for Olmsted County, Minnesota residents diagnosed with melanoma from 01/01/1970 to 12/21/2020. Age- and sex-adjusted incidence and disease-specific mortality are calculated.

Results

Two thousand three hundred ten primary cutaneous melanomas were identified. Current age- and sex-adjusted incidence rates increased 11.1-fold since 1970s (P < .001). Over the last decade, there is an overall 1.21-fold (P < .002) increase, with a 1.36-fold increase (P < .002) among females and no significant increase among males (1.09-fold increase, P < .329). Melanoma-specific mortality decreased from 26.7% in 1970s to 1.5% in 2010s, with a hazard ratio (HR) reduction of 0.73 (P < .001) per 5-year period. Increased mortality was associated with Breslow thickness (HR 1.35, P < .001), age at diagnosis (HR 1.13, P = .001) left anatomic site (HR 1.98, P = .016), and nodular histogenic subtype (HR 3.08, P < .001).

Limitations

Retrospective nature and focused geographic investigation.

Conclusion

Melanoma incidence has continued to increase over the past decade, most significantly in females aged 40+. Trend variations among age and sex cohorts suggests external factors beyond overdiagnosis may be responsible. Disease-specific mortality of melanoma continues to decrease over the last 50 years.

背景基于国家癌症报告的登记数据虽然可靠,但在发病趋势方面缺乏精细度。在发病率上升而死亡率没有相应上升的情况下,专家对黑色素瘤过度诊断的可能性仍然存在争议。方法利用罗切斯特流行病学项目对明尼苏达州奥姆斯特德县从 1970 年 1 月 1 日至 2020 年 12 月 21 日期间确诊为黑色素瘤的居民进行多中心、基于人群的流行病学研究。结果发现了 2310 例原发性皮肤黑色素瘤。自 20 世纪 70 年代以来,经年龄和性别调整后的发病率增加了 11.1 倍(P < .001)。在过去十年中,发病率总体上升了 1.21 倍(P < .002),其中女性发病率上升了 1.36 倍(P < .002),男性发病率没有显著上升(1.09 倍,P < .329)。黑色素瘤特异性死亡率从20世纪70年代的26.7%降至2010年代的1.5%,每5年的危险比(HR)降低0.73(P < .001)。死亡率的增加与布雷斯罗厚度(HR 1.35,P < .001)、诊断年龄(HR 1.13,P = .001)、左侧解剖部位(HR 1.98,P = .016)和结节性组织亚型(HR 3.08,P < .001)有关。不同年龄和性别组群之间的趋势变化表明,除了过度诊断外,外部因素也可能是原因之一。过去 50 年来,黑色素瘤的疾病特异性死亡率持续下降。
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引用次数: 0
Racial differences in tolerability of topical retinoids: A 15-year single-center retrospective cohort study 外用维甲酸耐受性的种族差异:一项为期 15 年的单中心回顾性队列研究
Pub Date : 2024-05-09 DOI: 10.1016/j.jdin.2024.04.012
Yu-Feng Chang MD, MS , Li-Chi Chen MD , Dae Hyun Kim MD, ScD , Sarah Hahn Hsu MD , Hye Jin Chung MD, MMSc
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引用次数: 0
Psoriasis is associated with increased risk of other autoimmune diseases: A retrospective case-control study using the All of Us research database 银屑病与罹患其他自身免疫性疾病的风险增加有关:利用 "我们所有人 "研究数据库开展的一项回顾性病例对照研究
Pub Date : 2024-05-09 DOI: 10.1016/j.jdin.2024.03.018
Priya Marella MBA , Shari R. Lipner MD, PhD
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引用次数: 0
Skin care habits of patients with eczema at Kiambu Level 5 Hospital, Kiambu county, Kenya: A retrospective cross-sectional study 肯尼亚基安布县基安布五级医院湿疹患者的皮肤护理习惯:回顾性横断面研究
Pub Date : 2024-05-07 DOI: 10.1016/j.jdin.2024.04.011
Winnie Njenga MBChB, MSc , Magoma Mwancha-Kwasa MBChB, MPH , Kinara Fossa MSc , Prabhjot Kaur Juttla BSc , Fredrick Kimani BSc , Winfred Mwikya Dip , Francis Makokha PhD , Hannah Wanyika MBChB, PhD

Background

There is a dearth of data on eczema from the African continent despite the purported increasing burden.

Objectives

To describe the prevalence of eczema at Kiambu Level 5 Hospital and patient skincare.

Methods

A descriptive retrospective cross-sectional research design was performed describing the period between 2016 and 2020. Data analysis was done using STATA Version 13. Geospatial mapping of patient residence was also conducted.

Results

Eczema was the most common skin condition diagnosed with a prevalence of 25.5%. Majority of the patients favored the use of non-conventional products such as bar soap and milking jelly as routine skincare products. Geospatial mapping demonstrated a higher prevalence of eczema in the urban areas and also revealed access to a specialist as a contributor to health-seeking behavior.

Limitations

Subtypes of eczema were not described and this data only reflects 1 facility serving an entire county.

Conclusion

The prevalence of eczema in Kiambu Level 5 Hospital mirrors the increasing global burden of eczema. Urban environments have a higher density of eczema in Kiambu. More research is needed to decipher the impact of the preferred non-conventional skin care products on eczema.

背景尽管非洲大陆的湿疹负担据称日益加重,但有关湿疹的数据却十分匮乏。目的描述基安布五级医院的湿疹患病率和患者护肤情况。数据分析采用 STATA 13 版本。结果湿疹是最常见的皮肤病,发病率为 25.5%。大多数患者喜欢使用非传统产品,如肥皂和挤奶果冻作为日常护肤品。地理空间分布图显示,湿疹在城市地区的发病率较高,同时还显示,能否找到专科医生也是影响患者就医行为的一个因素。结论基昂布五级医院的湿疹发病率反映了全球湿疹负担日益加重的趋势。在基安布,城市环境中的湿疹发病率较高。需要开展更多研究,以了解首选的非传统护肤品对湿疹的影响。
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引用次数: 0
Artificial intelligence tools may be superior to traditional approaches for translating patient handouts: A pilot study 人工智能工具在翻译患者手册方面可能优于传统方法:一项试点研究
Pub Date : 2024-05-06 DOI: 10.1016/j.jdin.2024.04.007
Sydney Dong BS , Sijia Zhang BA , Helen Park MD , Jessica De La Rosa MD , AlReem Al-Nabti MD , Vy Xuan Pham BA , Andres Cedeno BS , Isabella Toledo BA , Anika Jallorina BS , Jennifer Laborada MD , Bryan Sun MD, PhD , Regina Wang MD , George Hightower MD, PhD
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引用次数: 0
Isotretinoin for rosacea: A systematic review 异维A酸作为红斑痤疮的治疗策略:系统回顾
Pub Date : 2024-05-06 DOI: 10.1016/j.jdin.2024.04.009
Sapana Desai MD, Adam Friedman MD
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引用次数: 0
Association between body mass index and vitiligo distribution: An observational cohort study 体重指数与白癜风分布之间的关系:观察性队列研究
Pub Date : 2024-05-04 DOI: 10.1016/j.jdin.2024.03.029
Ross O’Hagan MD , Samir Kamat MD , Shira Wieder MD , Marcel Perl MD , Jonathan I. Silverberg MD, PhD, MPH , Nanette B. Silverberg MD
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引用次数: 0
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