Pub Date : 2022-12-01DOI: 10.52547/jommid.10.4.199
Roozbeh Esalatmanesh, M. Sharif, K. Esalatmanesh, Shirin Heidari, Z. Soleimani
Introduction: Brucellosis is a zoonotic disease in humans and animals and is a worldwide public health problem. Changes in inflammatory cytokines levels might be deployed as markers for diagnosing infectious diseases from non-infectious medical conditions. This study aimed to evaluate the relationship between serum levels of interleukin-17 (IL-17) and transforming growth factor-beta (TGF-β) in pediatric brucellosis. Methods: The present case-control study included 40 brucellosis patients and 40 matched healthy controls. Serum levels of inflammatory cytokines were measured by ELISA
{"title":"Evaluation of Serum Interleukin-17, Transforming Growth Factor-beta Levels in Brucellosis Patients Before and After Treatment","authors":"Roozbeh Esalatmanesh, M. Sharif, K. Esalatmanesh, Shirin Heidari, Z. Soleimani","doi":"10.52547/jommid.10.4.199","DOIUrl":"https://doi.org/10.52547/jommid.10.4.199","url":null,"abstract":"Introduction: Brucellosis is a zoonotic disease in humans and animals and is a worldwide public health problem. Changes in inflammatory cytokines levels might be deployed as markers for diagnosing infectious diseases from non-infectious medical conditions. This study aimed to evaluate the relationship between serum levels of interleukin-17 (IL-17) and transforming growth factor-beta (TGF-β) in pediatric brucellosis. Methods: The present case-control study included 40 brucellosis patients and 40 matched healthy controls. Serum levels of inflammatory cytokines were measured by ELISA","PeriodicalId":34460,"journal":{"name":"Journal of Medical Microbiology and Infectious Diseases","volume":"60 6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90691617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-12-01DOI: 10.52547/jommid.10.4.192
S. Nouri Gharajalar, M. Hassanzadeh, R. Mahmoudi, Paria Emamverdizadeh
{"title":"Antibacterial Activity of Trachyspermum ammi Essential Oil Against Streptococcus mutans Isolated from Human Dental Plaques","authors":"S. Nouri Gharajalar, M. Hassanzadeh, R. Mahmoudi, Paria Emamverdizadeh","doi":"10.52547/jommid.10.4.192","DOIUrl":"https://doi.org/10.52547/jommid.10.4.192","url":null,"abstract":"","PeriodicalId":34460,"journal":{"name":"Journal of Medical Microbiology and Infectious Diseases","volume":"80 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83383989","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-12-01DOI: 10.52547/jommid.10.4.163
Roshika Tyagi, C. Paul, Juni Banerjee, R. Kaul, Shuvomoy Banerjee
{"title":"Virus Association with Gastric Inflammation and Cancer: An Updated Overview","authors":"Roshika Tyagi, C. Paul, Juni Banerjee, R. Kaul, Shuvomoy Banerjee","doi":"10.52547/jommid.10.4.163","DOIUrl":"https://doi.org/10.52547/jommid.10.4.163","url":null,"abstract":"","PeriodicalId":34460,"journal":{"name":"Journal of Medical Microbiology and Infectious Diseases","volume":"41 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79059118","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-12-01DOI: 10.52547/jommid.10.4.157
Z. Taghinejad, M. Asgharzadeh, Behroz Mahdavi Poor, V. Asgharzadeh, H. Samadi kafil, J. Rashedi
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is a significant health and financial issue in the current century. Despite significant attempts to manage the illness, the transmission routes of the virus and its widespread genomic mutations have led to an increasing number of new infections and mortality rates. In the absence of specific treatment for this new virus, identifying and managing factors affecting the prognosis of the disease is one of the critical strategies to reduce disease mortality. Patients with iron deficiency anemia (IDA), who account for an estimated half a billion people globally, are more prone to infections due to immune system disorders. Since they visit hospitals more frequently for follow-up care and diagnosis, they are more susceptible to becoming infected with SARS-CoV-2. Once infected with SARS-CoV-2, low hemoglobin (Hb) levels and compromised immune systems disrupt the restriction of infection in these individuals, ultimately leading to severe complications of COVID-19.
{"title":"Iron Deficiency Anemia and COVID-19","authors":"Z. Taghinejad, M. Asgharzadeh, Behroz Mahdavi Poor, V. Asgharzadeh, H. Samadi kafil, J. Rashedi","doi":"10.52547/jommid.10.4.157","DOIUrl":"https://doi.org/10.52547/jommid.10.4.157","url":null,"abstract":"Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is a significant health and financial issue in the current century. Despite significant attempts to manage the illness, the transmission routes of the virus and its widespread genomic mutations have led to an increasing number of new infections and mortality rates. In the absence of specific treatment for this new virus, identifying and managing factors affecting the prognosis of the disease is one of the critical strategies to reduce disease mortality. Patients with iron deficiency anemia (IDA), who account for an estimated half a billion people globally, are more prone to infections due to immune system disorders. Since they visit hospitals more frequently for follow-up care and diagnosis, they are more susceptible to becoming infected with SARS-CoV-2. Once infected with SARS-CoV-2, low hemoglobin (Hb) levels and compromised immune systems disrupt the restriction of infection in these individuals, ultimately leading to severe complications of COVID-19.","PeriodicalId":34460,"journal":{"name":"Journal of Medical Microbiology and Infectious Diseases","volume":"90 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90077177","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-12-01DOI: 10.52547/jommid.10.4.179
Seth Offei Addo, Jennifer Oppong, Elisha Monikey Achawe, Barbara Baah Nketia, Prince Boateng Agyei, John Asiedu Larbi
{"title":"Filth Flies As Carriers of Intestinal Parasites And Fungi in a Tertiary Institution in Ghana","authors":"Seth Offei Addo, Jennifer Oppong, Elisha Monikey Achawe, Barbara Baah Nketia, Prince Boateng Agyei, John Asiedu Larbi","doi":"10.52547/jommid.10.4.179","DOIUrl":"https://doi.org/10.52547/jommid.10.4.179","url":null,"abstract":"","PeriodicalId":34460,"journal":{"name":"Journal of Medical Microbiology and Infectious Diseases","volume":"65 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87977342","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-12-01DOI: 10.52547/jommid.10.4.186
Azam Aghili Amjad, M. Niakan, Fatemeh Sameni, Shahriar Bakhti, Mansoor Khaledi, H. Afkhami, R. Mirnejad
{"title":"The adeH and adeS Efflux Pump Genes in Imipenem and Colistin-Resistant Acinetobacter baumannii Clinical Isolates","authors":"Azam Aghili Amjad, M. Niakan, Fatemeh Sameni, Shahriar Bakhti, Mansoor Khaledi, H. Afkhami, R. Mirnejad","doi":"10.52547/jommid.10.4.186","DOIUrl":"https://doi.org/10.52547/jommid.10.4.186","url":null,"abstract":"","PeriodicalId":34460,"journal":{"name":"Journal of Medical Microbiology and Infectious Diseases","volume":"4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78874776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-09-01DOI: 10.52547/jommid.10.3.104
S. Akhter, A. Nazir, Ovais Karnain, M. Rouf
Introduction: The increased frequency of Methicillin - resistant Staphylococcus aureus infections has led to renewed interest in the macrolide-lincosamide streptogramin B (MLS) group of antibiotics. Resistance to these antibiotics may be constitutive or inducible. Isolates resistant to erythromycin may show false in vitro susceptibility to clindamycin, leading to therapeutic failures. This study investigated the utility of the D-Test for detecting inducible clindamycin resistance in methicillin-resistant S. aureus isolates and determining the prevalence of various phenotypes in our region. Methods: For detecting inducible clindamycin resistance, a D-test using erythromycin and clindamycin as per CLSI guidelines was performed, and four different phenotypes were interpreted as methicillin-sensitive (MS) phenotype (D-test negative), inducible MLSB (iMLSB) phenotype (D-test positive), constitutive MLSB phenotype and sensitive to both. Results : Of the 987 isolates tested, 400 (40.53%) were MRSA. The prevalence of iMLSB, cMLSB phenotype, MS phenotype and sensitive phenotype in MRSA isolates was 42.5%, 10.5%, 28% and 19%, respectively. The iMLSB and cMLSB phenotypes were higher in males (24.75%, 6.25%) than females ( P -value = 0.137). The majority of MRSA isolates originated from pus (83%). All S. aureus isolates showed 100% sensitivity to vancomycin and linezolid. Conclusion : This study emphasizes the prevalence of inducible clindamycin resistance in MRSA in our setup. Incorporating the D-test into the routine Kirby–Bauer disk diffusion method in clinical microbiology laboratories will help clinicians make judicious use of clindamycin, minimizing treatment failure.
{"title":"Prevalence of Constitutive and Inducible Clindamycin Resistance among Methicillin-Resistant Staphylococcus aureus Isolates in a Tertiary Care Hospital, Kashmir Valley","authors":"S. Akhter, A. Nazir, Ovais Karnain, M. Rouf","doi":"10.52547/jommid.10.3.104","DOIUrl":"https://doi.org/10.52547/jommid.10.3.104","url":null,"abstract":"Introduction: The increased frequency of Methicillin - resistant Staphylococcus aureus infections has led to renewed interest in the macrolide-lincosamide streptogramin B (MLS) group of antibiotics. Resistance to these antibiotics may be constitutive or inducible. Isolates resistant to erythromycin may show false in vitro susceptibility to clindamycin, leading to therapeutic failures. This study investigated the utility of the D-Test for detecting inducible clindamycin resistance in methicillin-resistant S. aureus isolates and determining the prevalence of various phenotypes in our region. Methods: For detecting inducible clindamycin resistance, a D-test using erythromycin and clindamycin as per CLSI guidelines was performed, and four different phenotypes were interpreted as methicillin-sensitive (MS) phenotype (D-test negative), inducible MLSB (iMLSB) phenotype (D-test positive), constitutive MLSB phenotype and sensitive to both. Results : Of the 987 isolates tested, 400 (40.53%) were MRSA. The prevalence of iMLSB, cMLSB phenotype, MS phenotype and sensitive phenotype in MRSA isolates was 42.5%, 10.5%, 28% and 19%, respectively. The iMLSB and cMLSB phenotypes were higher in males (24.75%, 6.25%) than females ( P -value = 0.137). The majority of MRSA isolates originated from pus (83%). All S. aureus isolates showed 100% sensitivity to vancomycin and linezolid. Conclusion : This study emphasizes the prevalence of inducible clindamycin resistance in MRSA in our setup. Incorporating the D-test into the routine Kirby–Bauer disk diffusion method in clinical microbiology laboratories will help clinicians make judicious use of clindamycin, minimizing treatment failure.","PeriodicalId":34460,"journal":{"name":"Journal of Medical Microbiology and Infectious Diseases","volume":"81 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90916263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-09-01DOI: 10.52547/jommid.10.3.129
Mahshid Saeedi, L. Fozouni
Introduction:
作品简介:
{"title":"Detection of Nosocomial Respiratory Infections among Hospitalized Patients in Intensive Care Unit: a Survey in Northern Iran","authors":"Mahshid Saeedi, L. Fozouni","doi":"10.52547/jommid.10.3.129","DOIUrl":"https://doi.org/10.52547/jommid.10.3.129","url":null,"abstract":"Introduction:","PeriodicalId":34460,"journal":{"name":"Journal of Medical Microbiology and Infectious Diseases","volume":"17 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89435161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-09-01DOI: 10.52547/jommid.10.3.122
Afsaneh Salimi, M. Rohani, M. Pourshafie
Introduction: Inflammatory bowel disease (IBD) is a group of chronic gastrointestinal disorders affecting millions worldwide. Several factors are involved in developing this disease, but gut microbiota is known to be one of the most critical factors. This study investigated the relationship between gut microbiota and IBD in a mouse model. Methods: In this study, two methods were used: chemical induction with dextran sulfate sodium (DSS) and biological induction with stool from a human with IBD (fecal microbiota transplantation) to induce inflammation in the gut of mice. The gut microbiota populations in both groups were studied using real-time PCR. In addition, the serum levels of inflammatory cytokines and the colon tissues of the mice were analyzed
{"title":"Investigating the Relation between the Gut Microbiota and Inflammatory Bowel Disease in a Mouse Model","authors":"Afsaneh Salimi, M. Rohani, M. Pourshafie","doi":"10.52547/jommid.10.3.122","DOIUrl":"https://doi.org/10.52547/jommid.10.3.122","url":null,"abstract":"Introduction: Inflammatory bowel disease (IBD) is a group of chronic gastrointestinal disorders affecting millions worldwide. Several factors are involved in developing this disease, but gut microbiota is known to be one of the most critical factors. This study investigated the relationship between gut microbiota and IBD in a mouse model. Methods: In this study, two methods were used: chemical induction with dextran sulfate sodium (DSS) and biological induction with stool from a human with IBD (fecal microbiota transplantation) to induce inflammation in the gut of mice. The gut microbiota populations in both groups were studied using real-time PCR. In addition, the serum levels of inflammatory cytokines and the colon tissues of the mice were analyzed","PeriodicalId":34460,"journal":{"name":"Journal of Medical Microbiology and Infectious Diseases","volume":"26 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78243129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-09-01DOI: 10.52547/jommid.10.3.149
Tayebeh Taghipour, M. Erami, Mojtaba Fakhrei, Hossein Hooshyar
Malaria is an imported disease in non-endemic regions of Iran. Imported malaria cases to Iran mostly come from illegal immigrants from neighboring eastern countries. The present study describes a case of imported malaria in a 14-month-old Afghan boy with prolonged fever, vomiting, and diarrhea. He was referred and hospitalized in Shahid Beheshti, Kashan, central Iran, in December 2021. He and his parents traveled and immigrated to Kashan, Iran, three weeks before hospitalization. After staining with Giemsa stain, a thin blood smear test showed Plasmodium vivax with the Schüffner's dots in red blood cells. The patient was treated with an antimalarial drug and discharged from the hospital with normal vital signs. Before arriving in Iran, all immigrants should receive a screening test or be checked for malaria symptoms.
{"title":"Imported Malaria in an Immigrant Toddler Boy in Kashan, a Non-Malaria Endemic Area, Central Iran","authors":"Tayebeh Taghipour, M. Erami, Mojtaba Fakhrei, Hossein Hooshyar","doi":"10.52547/jommid.10.3.149","DOIUrl":"https://doi.org/10.52547/jommid.10.3.149","url":null,"abstract":"Malaria is an imported disease in non-endemic regions of Iran. Imported malaria cases to Iran mostly come from illegal immigrants from neighboring eastern countries. The present study describes a case of imported malaria in a 14-month-old Afghan boy with prolonged fever, vomiting, and diarrhea. He was referred and hospitalized in Shahid Beheshti, Kashan, central Iran, in December 2021. He and his parents traveled and immigrated to Kashan, Iran, three weeks before hospitalization. After staining with Giemsa stain, a thin blood smear test showed Plasmodium vivax with the Schüffner's dots in red blood cells. The patient was treated with an antimalarial drug and discharged from the hospital with normal vital signs. Before arriving in Iran, all immigrants should receive a screening test or be checked for malaria symptoms.","PeriodicalId":34460,"journal":{"name":"Journal of Medical Microbiology and Infectious Diseases","volume":"54 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78175974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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