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A Population based Study on Self Medication Practice in Pakistan 巴基斯坦自我用药实践的人口基础研究
Pub Date : 2022-08-31 DOI: 10.47723/kcmj.v18i2.847
K. Khan, Aqsa Zaman, Furqan Khurshid Hashmi, R. Khan
Background: The risk of antibiotics resistance (AR) increases due to excessive of antibiotics either by health care provider or by the patients.Objective: The assessment of the self-medication Practice of over the counter drugs and other prescription drugs and its associated risk factor.Subjects and Methods: Study design: A descriptive study was conducted from “20th December 2019 to 08th January 2021”. A pre validated and structured questionnaire in English and Urdu language was created to avoid language barrier including personal detail, reasons and source and knowledge about over the counter drugs and Antibiotics. Sample of the study was randomly selected. Data was analyzed by software SPSS version 22.Results: Out of n=3388 respondents, the prevalence of self -medication practice of OTC drugs and antibiotics as self – medication practice in all of the respondents is 88% and 85.9% respectively. Knowledge of the respondents about the use of the antibiotics as well as side effects of antibiotics was 40.7% and 15.3% respectively. Headache, fever, cough and stomach problem were the minor ailments for which   majority of OTC drugs and antibiotics used respectively. The commonly used OTC drugs and OPDEA were Paracetamol and Omeprazole. The commonly used antibiotics were Metronidazole, Amoxicillin and Clavulanic acid and Ciprofloxacin.Conclusion: Government should make policies to train pharmacist in the community for antibiotics stewardship and standard treatment guidelines through educational workshops. Our future study will be on how to minimize antimicrobial resistance in the developing countries Conclusion: Government should make policies to train pharmacist in the community for antibiotics stewardship and standard treatment guidelines through educational workshops. Our future study will be on how to minimize antimicrobial resistance in the developing countries.
背景:由于医护人员或患者过量使用抗生素,抗生素耐药性(AR)的风险增加。目的:评价非处方药和其他处方药的自我药疗行为及其相关危险因素。研究设计:一项描述性研究于“2019年12月20日至2021年1月8日”进行。为了避免语言障碍,使用英语和乌尔都语制作了一份预先验证的结构化问卷,包括个人信息、原因、来源和对非处方药物和抗生素的了解。研究的样本是随机选择的。数据分析采用SPSS version 22软件。结果:在n=3388名受访者中,所有受访者将非处方药和抗生素作为自我用药实践的比例分别为88%和85.9%。受访者对抗生素使用和抗生素副作用的知晓率分别为40.7%和15.3%。头痛、发烧、咳嗽和胃病分别是大多数非处方药和抗生素使用的小病。常用的非处方药和OPDEA为扑热息痛和奥美拉唑。常用的抗生素有甲硝唑、阿莫西林、克拉维酸和环丙沙星。结论:政府应制定相关政策,通过教育研讨会对社区药师进行抗生素管理和标准治疗指南的培训。结论:政府应制定政策,通过教育讲习班培训社区药剂师进行抗生素管理和标准治疗指南的培训。我们未来的研究将是如何最大限度地减少发展中国家的抗菌素耐药性。
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引用次数: 0
Antimicrobial Activity of Lepidium Sativum against Multi drug resistant and sensitive Pseudomonas aeruginosa from clinical isolates, Khartoum State, Sudan 枸杞对多重耐药和敏感铜绿假单胞菌的抑菌活性研究
Pub Date : 2022-08-31 DOI: 10.47723/kcmj.v18i2.807
Akram Khalid Mubarak Margan, Mohammed Hussein Arbab, Sara Elsheikh Mohammed, Ahmed Saeed Kabbashi Saeed Kabbashi, Abubaker Agbash Baraka, Nagla Abdelmounaim Mohammed Ahmed
Background: L. sativum, are traditionally used for the treatment of various diseases and thought to have medicinal value. Isolates from many part of the world is now multidrug resistant. Therefore, there is an urgent need to look for and test an alternative herbal drug.Objective: The present study aimed to evaluate the antibacterial activity of L. Sativum seed extract against multi drug resistant (MDR) and sensitive Pseudomonas aeruginosa clinical isolates.Subjects and Methods: An ethanolic and aqueous stock extracts were prepared from L.  sativum seed plant then serial dilutions were prepared and the obtained concentrations (50, 25, 12.5 and 6.2 mg/ml) were tested against 30 multidrug-resistant and 35 sensitive clinical isolates of Pseudomonas aeruginosa using wells diffusion method.Results: It was found that L. sativum seed extracts had antimicrobial activity against MDR and sensitive isolates at different concentrations of 100, 50 and 25 according to the mean ± SD (standard deviation) of the maximum zones of inhibition. The total number of isolates that were sensitive to both extracts were 49/130 (37%) which represented 17/60 (28.3%) MDR and 32/70 (45.7%) sensitive isolates. The aqueous extract exhibited more inhibitory effect than ethanolic extract 43 (66%) vs. 6 (9%) against the examined isolates (n=65).Conclusion: The study concluded that the L. sativum extracts had an antibacterial activity against the susceptible and MDR isolates which may enable it to be used an alternative treatment for medicinal purposes.
背景:L. sativum,传统上用于治疗各种疾病,被认为具有药用价值。来自世界许多地方的分离株现在具有多重耐药性。因此,迫切需要寻找和测试一种替代草药。目的:评价苜蓿种子提取物对耐多药(MDR)和敏感铜绿假单胞菌临床分离株的抑菌活性。对象与方法:采用孔扩散法分别对30株铜绿假单胞菌临床耐药和敏感分离株进行了50、25、12.5和6.2 mg/ml的稀释试验。结果:发现L. sativum种子提取物在100、50和25浓度下对MDR和敏感菌株均有抑菌活性,其最大抑菌区均为平均值±SD(标准差)。对两种提取物均敏感的菌株总数为49/130株(37%),其中耐多药菌株17/60株(28.3%),敏感菌株32/70株(45.7%)。水提物比乙醇提物43(66%)比6(9%)对检测的分离株(n=65)表现出更强的抑制作用。结论:本研究认为,苜蓿提取物对易感菌和耐多药菌株具有抗菌活性,可作为替代药物。
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引用次数: 0
Acute Appendicitis and Multisystemic Inflammatory Syndrome due to COVID-19: a Case Report and Literature Review COVID-19致急性阑尾炎和多系统炎症综合征1例报告并文献复习
Pub Date : 2022-08-31 DOI: 10.47723/kcmj.v18i2.823
M. Hashlamoun, R. M. Qafesha, R. Salhab, B.M. Huseein, A. Benmelouka, Afnan W M Jobran
The prevalence of gastrointestinal symptoms of COVID-19 is variable with different types of presentations. Some of them many present with manifestations mimicking surgical emergencies. Yet, the pathophysiology of acute abdomen in the context of COVID-19 remains unclear. We present a case of a previously healthy child who presented with acute appendicitis with multisystemic inflammatory syndrome. We also highlight the necessity of considering the gastrointestinal symptoms of COVID-19 infection in pediatric patients in order to avoid misdiagnosis and further complications.
COVID-19胃肠道症状的患病率随表现类型的不同而变化。其中一些人表现出类似外科急诊的症状。然而,COVID-19背景下急腹症的病理生理机制尚不清楚。我们提出一个病例以前健康的儿童谁提出了急性阑尾炎与多系统炎症综合征。我们还强调,为避免误诊和进一步的并发症,必须考虑儿童患者COVID-19感染的胃肠道症状。
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引用次数: 0
Xenotransplantation: Fact or Magic 异种移植:事实还是魔法
Pub Date : 2022-08-31 DOI: 10.47723/kcmj.v18i2.869
B. Mahdi
The knowledge of transferring body organs or tissues appears in the ancient mythology of Roman, Greek, Indian, Chinese, and Egyptian civilizations. The stories of organ transplants performed by GODs and health care’s using organs from cadaveric and after that transplantation change from lore to medical training
移植身体器官或组织的知识出现在罗马、希腊、印度、中国和埃及文明的古代神话中。上帝进行器官移植的故事和医疗机构使用尸体器官以及移植后的器官的故事从爱情变成了医疗培训
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引用次数: 0
Detection of Parvovirus B19 DNA in pregnant Sudanese women attending The Military hospital using Nested PCR technique 应用套式PCR技术检测苏丹军队医院孕妇细小病毒B19 DNA
Pub Date : 2022-08-31 DOI: 10.47723/kcmj.v18i2.788
T. Abdelkabeer, Nusaiba Elhadi Mohammed, Jala Suliman Khider, M. Yassin, A. Idris
Background: Parvovirus B19 is a human pathogenic virus associated with a wide range of clinical conditions. During pregnancy congenital infection with parvovirus B19 can be associated with poor outcome, including miscarriage, fetal anemia and non-immune hydrops.  Objective: The study aimed to determine the prevalenceof Parvovirus B19 DNA in pregnant women attending the Military hospital in Khartoum, demonstrating the association between the virus and poor pregnancy outcomes.Subjects and methods: This study was a cross sectional study, testing pregnant Sudanese women whole blood samples (n= 97) for the presence of Parvovirus B19 DNA using nested PCR technique.Result: Two samples were found positive for Parvovirus B19 DNA out of the total number of samples screened.Conclusions: The prevalence of Parvovirus B19 DNA among pregnant women attending the Military hospital was 2.1%.
背景:细小病毒B19是一种与多种临床疾病相关的人类致病性病毒。妊娠期先天性细小病毒B19感染可导致不良后果,包括流产、胎儿贫血和非免疫性水肿。目的:本研究旨在确定在喀土穆军事医院就诊的孕妇中细小病毒B19 DNA的患病率,并证明该病毒与不良妊娠结局之间的关联。研究对象和方法:本研究是一项横断面研究,使用巢式PCR技术检测苏丹孕妇全血样本(n= 97)是否存在细小病毒B19 DNA。结果:2份样本中细小病毒B19 DNA阳性。结论:在部队医院就诊的孕妇中细小病毒B19 DNA感染率为2.1%。
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引用次数: 0
A Spotlight on the Experience of E-learning as a Learning Method for the Undergraduate Pediatric Nursing Students in Iraq during the COVID-19 Pandemic 关注新冠肺炎大流行期间伊拉克儿科护理本科学生电子学习的经验
Pub Date : 2022-08-31 DOI: 10.47723/kcmj.v18i2.804
M. Al-Mendalawi, Adraa Hussein, M. Al-Khalidi
    The emergence of COVID-19 has resulted in an unprecedented escalation in different aspects of human activities, including medical education. Students and educators across academic institutions have confronted various challenges in following the guidelines of protection against the disease on one hand and accomplishing learning curricula on the other hand. In this short view, we presented our experience in implementing e-learning to the undergraduate nursing students during the present COVID-19 pandemic emphasizing the learning content, barriers, and feedback of students and educators. We hope that this view will trigger the preparedness of nursing faculties in Iraq to deal with this new modality of learning and improve it should the COVID-19 pandemic keep on or a new pandemic emerges.
COVID-19的出现导致人类活动的不同方面前所未有的升级,包括医学教育。各学术机构的学生和教育工作者一方面在遵循预防疾病的指导方针,另一方面在完成学习课程方面面临着各种挑战。在这篇简短的文章中,我们介绍了我们在当前COVID-19大流行期间对本科护理学生实施电子学习的经验,强调了学习内容、障碍以及学生和教育者的反馈。我们希望,这一观点将促使伊拉克护理学院做好准备,应对这种新的学习方式,并在COVID-19大流行持续或出现新的大流行的情况下改进这种学习方式。
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引用次数: 0
Assessment of Lipid Profile among Sudanese patients with Type 2 Diabetes Mellitus 苏丹2型糖尿病患者血脂水平的评估
Pub Date : 2022-05-05 DOI: 10.47723/kcmj.v18i1.422
Rania Ali Abdalla Mohamed, Bakri Yousif Mohammed Noor, S. M. Ahmed, Abuagla M. Dafalla, Y. Mohammed, G. Modawe
Background: Diabetes mellitus is a major health issue that is one of the leading causes of cardiovascular disease. Recent studies have found a link between uncontrolled diabetes and cardiovascular disease, with dyslipidaemia predicting glycated-hemoglobin (HbA1c), which could be a major contributor to type 2 diabetes complications and etiology.Objectives: The objective of present study was estimate lipid profiles among control and uncontrolled type 2 diabetic patients.Subjects and Methods: Analytical case control based study, One hundred twenty participate were included in study, 70 patients with DM  as case group  refer to Abuagala Center and difference follow up diabetic center  and 50 non diabetic subjects taken as control group males and females their  age between 20 to 80 years. Fasting blood glucose (FBG), blood HbA1c, and serum lipid parameters were measured by CobseC311 from Roche instrument. Data was analyzed using SPSS version 22, which expressed as (mean±SD) with p.value.Result:Among120 participant the levels of fasting blood glucose,blood HbA1c,and Triglyceridewereincreased significantly in T2DM (161.7±72.5mg/dl), (8.88±3.9 %), (121±61.9 mg/dl)when compare with control group(91.28±13.9), (5.7±0.50), (80±11.7) with P.value (0.000),while total Cholesterol, High Density Lipoprotein, and Low Density Lipoprotein were not significant different in T2DM when compared with control group. There was weak positive correlation between HbA1c with FBG, CHOL, LDL, and HDL (r = 0.207, P =0.089, r = 0.186, P =0.124, r = 0.167, P =0.168, r = 0.308, P =0.01) respectively, while TG hadweak negative correlation (r =- 0.146, P =0.228). Conclusion: The results indicated to considerable increase in the lipid profile levels in type two diabetic patients when compared with healthy controls group which may lead to increase in coronary risk factors.
背景:糖尿病是一个主要的健康问题,是导致心血管疾病的主要原因之一。最近的研究发现,不受控制的糖尿病与心血管疾病之间存在联系,血脂异常可预测糖化血红蛋白(HbA1c),这可能是2型糖尿病并发症和病因的主要因素。目的:本研究的目的是估计控制和未控制的2型糖尿病患者的血脂水平。研究对象与方法:以病例对照为基础的分析性研究,共纳入120名参与者,其中70名DM患者为病例组,参照Abuagala中心及糖尿病差异随访中心,50名非糖尿病患者为对照组,年龄在20 ~ 80岁之间。采用罗氏仪器CobseC311检测空腹血糖(FBG)、血糖化血红蛋白(HbA1c)和血脂参数。数据分析采用SPSS version 22,用p值表示(mean±SD)。结果:120例受试者中,T2DM患者的空腹血糖、血HbA1c、甘油三酯水平(161.7±72.5mg/dl)、(8.88±3.9%)、(121±61.9 mg/dl)较对照组(91.28±13.9)、(5.7±0.50)、(80±11.7)显著升高,p值(0.000),而T2DM患者的总胆固醇、高密度脂蛋白、低密度脂蛋白与对照组相比无显著差异。HbA1c与FBG、CHOL、LDL、HDL呈弱正相关(r = 0.207, P =0.089, r = 0.186, P =0.124, r = 0.167, P =0.168, r = 0.308, P =0.01), TG呈弱负相关(r =- 0.146, P =0.228)。结论:与健康对照组相比,2型糖尿病患者血脂水平明显升高,可能导致冠心病危险因素增加。
{"title":"Assessment of Lipid Profile among Sudanese patients with Type 2 Diabetes Mellitus","authors":"Rania Ali Abdalla Mohamed, Bakri Yousif Mohammed Noor, S. M. Ahmed, Abuagla M. Dafalla, Y. Mohammed, G. Modawe","doi":"10.47723/kcmj.v18i1.422","DOIUrl":"https://doi.org/10.47723/kcmj.v18i1.422","url":null,"abstract":"Background: Diabetes mellitus is a major health issue that is one of the leading causes of cardiovascular disease. Recent studies have found a link between uncontrolled diabetes and cardiovascular disease, with dyslipidaemia predicting glycated-hemoglobin (HbA1c), which could be a major contributor to type 2 diabetes complications and etiology.\u0000Objectives: The objective of present study was estimate lipid profiles among control and uncontrolled type 2 diabetic patients.\u0000Subjects and Methods: Analytical case control based study, One hundred twenty participate were included in study, 70 patients with DM  as case group  refer to Abuagala Center and difference follow up diabetic center  and 50 non diabetic subjects taken as control group males and females their  age between 20 to 80 years. Fasting blood glucose (FBG), blood HbA1c, and serum lipid parameters were measured by CobseC311 from Roche instrument. Data was analyzed using SPSS version 22, which expressed as (mean±SD) with p.value.\u0000Result:Among120 participant the levels of fasting blood glucose,blood HbA1c,and Triglyceridewereincreased significantly in T2DM (161.7±72.5mg/dl), (8.88±3.9 %), (121±61.9 mg/dl)when compare with control group(91.28±13.9), (5.7±0.50), (80±11.7) with P.value (0.000),while total Cholesterol, High Density Lipoprotein, and Low Density Lipoprotein were not significant different in T2DM when compared with control group. There was weak positive correlation between HbA1c with FBG, CHOL, LDL, and HDL (r = 0.207, P =0.089, r = 0.186, P =0.124, r = 0.167, P =0.168, r = 0.308, P =0.01) respectively, while TG hadweak negative correlation (r =- 0.146, P =0.228). \u0000Conclusion: The results indicated to considerable increase in the lipid profile levels in type two diabetic patients when compared with healthy controls group which may lead to increase in coronary risk factors.","PeriodicalId":34748,"journal":{"name":"mjlh klyh Tb lkndy","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43572231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Two Decades in the Journey of Al-Kindy College Medical Journal: Key Barriers, Achievements, and Prospects 《Al-Kindy学院医学杂志》的二十年历程:主要障碍、成就和前景
Pub Date : 2022-05-05 DOI: 10.47723/kcmj.v18i1.838
M. Al-Mendalawi
Apart from graduating five-star doctors, a particular medical college has the mission to motivate and offer researchers the opportunity to publish high-quality researches on various health problems and disseminate updated medical knowledge to a wide range of local and international readers. This could be accomplished by establishing a medical journal and releasing issues regularly
除了毕业的五星级医生外,某所医学院的使命是激励和提供研究人员发表关于各种健康问题的高质量研究的机会,并向广泛的本地和国际读者传播最新的医学知识。这可以通过建立一份医学期刊并定期发布期刊来实现
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引用次数: 0
Evaluation of podophyllin and Trichloroacetic acid for the treatment of genital warts in Iraqi female patients 鬼臼碱与三氯乙酸治疗伊拉克女性生殖器疣的疗效评价
Pub Date : 2022-05-05 DOI: 10.47723/kcmj.v18i1.276
Lama Altaha
Background: human paillomavirus infections (genital warts) are the most frequent sexually transmitted viral infections. a wide range of treatment options is available with different efficacy.Objective: To evaluate the efficacy of podophyllin, trichloracetic acid (TCA) in the treatment of genital warts and side effects of them.Subjects and methods: a total of sixty patients with genital warts were randomly selected, 30 in each group, in the Department of Dermatology, medical city for a Duration of 11 months from January 2009 to December 2009 treated with 35 % podophyllin in the tincture of benzoin or 50%  TCA) .Forty-eight patients were followed up for three months.Results: warts cleared in 63% and 70% of the patients after treatment with podophyllin and TCA respectively within 3 months. Soreness happened in 6 patients with podophyllin and in 9 patients with TCA. small ulcers happened in 1 patient by podophyllin and 2 patients with TCA. pain was in 5 patients treated by podophyllin and in 6 patients treated by TCA. erythema was noticed in 10 patients treated by podophyllin and in 11 patients treated by TCA.Conclusion:  there was a higher clearance rate with TCA and earlier response. The occurrence of adverse reactions is little more with TCA
背景:人类乳头瘤病毒感染(生殖器疣)是最常见的性传播病毒感染。有多种不同疗效的治疗方案可供选择。目的:评价泊多林、三氯乙酸(TCA)治疗生殖器疣的疗效及不良反应。受试者和方法:从2009年1月至2009年12月,在医疗城市皮肤科随机选择60名生殖器疣患者,每组30名,为期11个月,用35%的苯偶姻酊剂或50%的TCA治疗。48名患者随访3个月。结果:泊多林和TCA治疗后,3个月内疣体清除率分别为63%和70%。泊多林组6例,TCA组9例。小溃疡发生在1例泊多林和2例TCA患者中。波多林治疗的5例患者疼痛,TCA治疗的6例患者疼痛。10例泊多林治疗患者和11例TCA治疗患者出现红斑。结论:TCA清除率高,反应早。TCA的不良反应发生率略高
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引用次数: 0
Correlation between Body Mass Index and Nonalcoholic Fatty Liver Disease 体重指数与非酒精性脂肪肝的相关性研究
Pub Date : 2022-05-05 DOI: 10.47723/kcmj.v18i1.425
Abdulhadi Alrubaie, R. E. Rezqallah, M. A. Ahmed, S. Musa, Maitham H Al-Qanbar
Background: Non-alcoholic fatty liver disease (NAFLD) is the most common liver disorder globally. The prevalence is 25% worldwide, distributed widely in different populations and regions. The highest rates are reported for the Middle East (32%). Due to modern lifestyles and diet, there has been a persistent increase in the number of NAFLD patients. This increase occurred at the same time  where there were also increases in the number of people considered being obese all over the world. By analyzing fatty liver risk factors, studies found that body mass index, one of the most classical epidemiological indexes assessing obesity, was associated with the risk of fatty liver.Objectives: To assess age, sex, and body mass index (BMI) as risk factors in NAFLD.Subjects and Methods: It is a case-control cross-sectional study from September 2020 till June 2021  which included all obese patients consulted the obesity research and therapy unit during the period of the study. Age and sex were recorded, body mass indices were calculated for all patients and categorized into normal with BMI < 25kg/m2, overweight with BMI 25-30 kg/m2, and obese with BMI > 30 kg/m2, ultrasonography was done to them to diagnose fatty liver changes which were categorized into three grades; mild, moderate and severeResults: 192 patients were enrolled in the study with an age range from 18-55 years with a mean of 38.09, males were 48 and females were 144. Sever NAFLD is present in 2.8% of obese females and 5.5% of obese male with 0% in normal and overweight individuals.Conclusion: NAFLD was more prevalent with increasing BMI and age in all sexes.
背景:非酒精性脂肪肝(NAFLD)是全球最常见的肝脏疾病。全世界的流行率为25%,广泛分布在不同的人群和地区。据报道,中东的发病率最高(32%)。由于现代生活方式和饮食,NAFLD患者的数量持续增加。这一增长发生的同时,全世界被认为肥胖的人数也在增加。通过分析脂肪肝的危险因素,研究发现,体重指数是评估肥胖的最经典的流行病学指标之一,与脂肪肝的风险相关。目的:评估年龄、性别和体重指数(BMI)作为NAFLD的危险因素。受试者和方法:这是一项从2020年9月到2021年6月的病例对照横断面研究,包括研究期间咨询肥胖研究和治疗单位的所有肥胖患者。记录年龄和性别,计算所有患者的体重指数,并将其分为BMI<25kg/m2的正常、BMI 25-30kg/m2的超重和BMI>30kg/m2的肥胖,对其进行超声检查以诊断脂肪肝变化,分为三级;结果:本研究共纳入192例患者,年龄18-55岁,平均38.09岁,男性48例,女性144例。严重NAFLD在2.8%的肥胖女性和5.5%的肥胖男性中存在,在正常和超重个体中为0%。结论:随着BMI和年龄的增加,NAFLD在所有性别中都更为普遍。
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引用次数: 0
期刊
mjlh klyh Tb lkndy
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