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Impact of diabetes mellitus on acute and short term left ventricular longitudinal systolic strain recovery after percutaneous coronary intervention in ischemic hypertensive patients 糖尿病对缺血性高血压患者经皮冠状动脉介入治疗后急性和短期左室纵向收缩应变恢复的影响
Pub Date : 2023-07-01 DOI: 10.21608/svuijm.2023.202042.1556
Areej Alkhateeb, Nihal Salah Abd Elrady, Ahlam Mohammed Sabrah Ali, Abdelazim Hashim
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引用次数: 1
Impact of the follicular fluid Coenzyme Q10 level in women undergoing intracytoplasmic sperm injection (ICSI) on the pregnancy rate 卵胞浆内单精子注射(ICSI)妇女卵泡液辅酶Q10水平对妊娠率的影响
Pub Date : 2023-07-01 DOI: 10.21608/svuijm.2023.207121.1578
M. Iwes, Mohamed Atef ELZarka, H. Fayed, A. Abdellah, M. A. Ahmed
Background: The most crucial problem with in vitro fertilization (IVF) cycles is still oocyte quality. The women age and the condition of their ovarian reserve are the primary determinants of oocyte quality. Objectives: to assess the effects of intracytoplasmic sperm injection (ICSI) on the result of pregnancies and the coenzyme Q10 (CoQ10) value in follicular fluid (FF) in the women who had the procedure. Patients and methods: this cohort investigation was conducted on 81 infertile patients (age between 20-42 years, both normal or poor responders ’ patients and patients with unexplained infertility) who underwent ICSI cycles. Results: patients were divided into two groups: the pregnant group (n= 32) and the non-pregnant group (n= 49). There was a statistically insignificant difference in antral follicle count (AFC), number of retrieved oocytes, number of embryos, number of metaphase II (MII) oocytes, and maturation index between pregnant and non-pregnant females. CoQ10 level in FF was substantially greater in pregnant than non-pregnant females. Conclusion: FF CoQ10 levels were positively correlated with eventual embryo quality and rates of conception. Our findings might be in favour of CoQ10 supplementation in women undergoing IVF for enhancement of the ovum and embryo quality.
背景:体外受精(IVF)周期中最关键的问题仍然是卵母细胞质量。女性的年龄和卵巢储备状况是卵母细胞质量的主要决定因素。目的:评价卵胞浆内单精子注射(ICSI)对妊娠结果和卵泡液(FF)中辅酶Q10 (CoQ10)值的影响。患者和方法:本队列研究纳入81例行ICSI周期的不孕症患者(年龄在20-42岁之间,包括正常或不良反应患者和不明原因不孕症患者)。结果:患者分为两组:妊娠组(n= 32)和非妊娠组(n= 49)。妊娠女性与未妊娠女性的窦卵泡计数(AFC)、取卵数、胚胎数、中期II卵母细胞数、成熟指数差异均无统计学意义。孕妇FF中CoQ10水平明显高于非孕妇。结论:FF辅酶q10水平与最终胚胎质量和受孕率呈正相关。我们的研究结果可能支持在接受体外受精的妇女中补充辅酶q10以提高卵子和胚胎质量。
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引用次数: 0
Impact of incentive spirometer on tip shoulder and right hypochondrial pain post laparoscopic cholecystectomy 激励性肺活量计对腹腔镜胆囊切除术后尖肩及右侧疑软骨疼痛的影响
Pub Date : 2023-07-01 DOI: 10.21608/svuijm.2023.207046.1573
Ayat Ahmad Mohamed Bakr, A. Ayad, A. Abdelraouf, Amir K. Abosayed
Background: Laparoscopic cholecystectomy (LC) continues to be more evolving. Pain remains the main annoying symptom postoperative. Objectives: This study aimed to proof if using incentive spirometry (IS) after LC will alleviate tip shoulder and right hypochondrial pain. Patients and Methods: On 90 patients undergoing LC at Kasr Al ainy hospitals and National Hepatology and Tropical Medicine Research Institute (NHTMRI) who were identified as having chronic calcular cholecystitis clinically and radiographically by ultrasonography, a prospective randomized controlled research was conducted. Two groups are formed. Group I (n = 45) receiving IS (consisting of 20 slow, deep breaths with a spirometry while sitting or semi sitting every 2 hours beginning at 2 hours postoperative) . There will be no respiratory over activity in Group II (n = 45). The "Visual Analogue Scale" (VAS) score used to further analyses shoulder and right hypochondrial pain. Results: Group I average pain score was significantly lower than Group II average pain score at 2 hours, 4 hours, and 6 hours (p-value 0.001), as well as at 8 hours (p-value =0.007). However, there were no significant differences between the study group and the control group on the second postoperative day (p-value = 0.900). In comparison to the control group, the study group receives a significantly lower dose of an analgesic (p-value 0.001). Conclusion:
背景:腹腔镜胆囊切除术(LC)不断发展。疼痛仍然是术后最主要的恼人症状。目的:本研究旨在证明在LC后使用刺激肺活量测量(IS)是否能减轻尖端肩和右侧疑软骨疼痛。患者与方法:对90例在Kasr Al - ainy医院和国家肝病与热带医学研究所(NHTMRI)行LC的临床和影像学诊断为慢性结石性胆囊炎的患者进行前瞻性随机对照研究。形成了两组。第一组(n = 45)接受IS(从术后2小时开始,每2小时进行20次缓慢的深呼吸,同时坐着或半坐着进行肺活量测定)。II组无呼吸过度活动(n = 45)。“视觉模拟量表”(VAS)评分用于进一步分析肩部和右侧疑软骨疼痛。结果:1组患者2小时、4小时、6小时及8小时平均疼痛评分显著低于2组患者(p值0.001)。然而,在术后第2天,研究组与对照组之间无显著差异(p值= 0.900)。与对照组相比,研究组接受的镇痛药剂量明显较低(p值0.001)。结论:
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引用次数: 0
Outcome of Acute Kidney Injury (AKI) in Coronavirus Disease 2019 (COVID-19) patients 2019冠状病毒病(COVID-19)患者急性肾损伤(AKI)的预后
Pub Date : 2023-07-01 DOI: 10.21608/svuijm.2023.202111.1557
A. A. Mohammed, Shimaa A. Mahmoud, Asmaa Abd Elhakim Nafady Hgo, Haggagy Mansour Mohammed, Ghada Mohammed Abd-EL Razek, Dina Badry Mohammed Rabea
Background: Coronavirus Disease 2019 (COVID-19) is a globally emerging illness, resulting in potential effects on public health and global economies. Objectives: To assess the incidence of Acute Kidney Injury among patients who are infected with COVID-19, and to evaluate risk factors. Patients and methods: This study enrolled 100 adult patients infected with COVID-19 and recently diagnosed with polymerase chain reaction (PCR). The patients were submitted to clinical examination and laboratory testing for ESR, CRP, CBC, Serum creatinine, and D-dimer. Patients were also assessed radiologically by CT Chest. High-resolution computed tomography Parenchymal abnormalities on HRCT were assessed. AKI patients were classified based on Acute Kidney Injury Network staging. Results : The mean age of all studied patients was 48.1 ± 10.8 years and mean BMI of all studied patients was 31.3 ± 4.6 kg/m 2 , 51 patients were males (51%) and 49 females (49%). There were 35 patients (35%) with a mild infection, 23 patients (23%) with moderate and 42 patients (42%) with severe in the studied patients. The overall AKI prevalence among COVID-19 patients was 18 %. All of them were grade III AKI. Our study revealed that old age, severity of infection, dyspnea, elevated CRP, ALT, AST, PT, INR, Urea and Creatinine were considerable distinct predictors for AKI. Conclusion : The Prevalence of AKI among COVID-19 patients was 18 %. Old age, the severity of infection, dyspnea, elevated CRP, increased serum urea, Creatinine were significant independent predictors for AKI.
背景:2019冠状病毒病(COVID-19)是一种全球性新发疾病,对公共卫生和全球经济造成潜在影响。目的:了解新型冠状病毒感染患者急性肾损伤的发生率,并对危险因素进行评价。患者和方法:本研究招募了100名感染COVID-19且最近诊断为聚合酶链反应(PCR)的成年患者。患者接受ESR、CRP、CBC、血清肌酐、d -二聚体的临床检查和实验室检测。同时对患者进行胸部CT放射学评估。评估HRCT上的实质异常。AKI患者根据急性肾损伤网络分期进行分类。结果:所有患者的平均年龄为48.1±10.8岁,平均BMI为31.3±4.6 kg/ m2,男性51例(51%),女性49例(49%)。轻度感染35例(35%),中度感染23例(23%),重度感染42例(42%)。COVID-19患者的AKI总体患病率为18%。均为III级AKI。我们的研究表明,年龄、感染严重程度、呼吸困难、CRP、ALT、AST、PT、INR、尿素和肌酐升高是AKI的显著预测因素。结论:COVID-19患者AKI患病率为18%。年龄、感染严重程度、呼吸困难、CRP升高、血清尿素、肌酐升高是AKI的重要独立预测因素。
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引用次数: 1
Antinuclear Antibodies: A demographic profile from a Tertiary Healthcare Centre of Delhi 抗核抗体:来自德里三级保健中心的人口统计资料
Pub Date : 2023-07-01 DOI: 10.21608/svuijm.2023.202492.1559
Krishna Sarkar, N. Ahmad, Debamita Banik, N. Singh
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引用次数: 0
Psychosocial impact of COVID-19 in rising generation: An observational study from India 2019冠状病毒病对年轻一代的社会心理影响:来自印度的一项观察性研究
Pub Date : 2023-07-01 DOI: 10.21608/svuijm.2023.186107.1487
G. Varshney, Nandini Dixit, P. Saini, P. Mishra
Background : Direct and indirect effects of the COVID-19 pandemic led to a significant change in the lives of children and adolescents. Changes in psychosocial behavior are one of them and are least noticed by parents and caregivers. Objectives: This study aimed to assess the mental and behavioral changes in children and adolescents of India before March 2020 and during the COVID-19 pandemic by Pediatric Symptom Checklist -17 (PSC-17). Patients and Methods : A cross-sectional observational study was conducted through an online questionnaire-based survey on children and adolescents of age group (5 -17 years) from 1st July to 15th July 2021 in India. Data were collected from parents regarding socio-demographic status, the behavior of study participants before and during the pandemic, and their perspective for the same. For statistical analysis chi-square test and the Mcnemar test was used. Results : Overall, 17.14% (77) of the study population scored positive during the covid pandemic on the total PSC-17 score. Participants residing in a metropolitan city, having nuclear family, and having no siblings were affected more as compared to others. The proportion of positive I scores (≥5), A score (≥7), E score (≥7) &total score (≥15) before and during COVID-19 were statistically significant among children. Conclusion: The psychological
背景:COVID-19大流行的直接和间接影响导致儿童和青少年生活发生重大变化。心理社会行为的变化就是其中之一,而父母和照顾者却很少注意到这一点。目的:本研究旨在通过儿科症状检查表-17 (PSC-17)评估2020年3月前和2019冠状病毒病大流行期间印度儿童和青少年的心理和行为变化。患者和方法:通过在线问卷调查,于2021年7月1日至7月15日在印度对5 -17岁年龄组的儿童和青少年进行了横断面观察性研究。从父母那里收集了有关社会人口状况、研究参与者在大流行之前和期间的行为以及他们对此的看法的数据。统计分析采用卡方检验和Mcnemar检验。结果:总体而言,17.14%(77)的研究人群在新冠肺炎大流行期间PSC-17总分呈阳性。居住在大城市、有核心家庭和没有兄弟姐妹的参与者受到的影响比其他人更大。儿童在新冠肺炎发病前、发病期间I评分≥5分、A评分≥7分、E评分≥7分、总分≥15分的阳性率差异均有统计学意义。结论:心理
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引用次数: 0
Effect of Tadalafil on Penile Duplex parameters in Erectile Dysfunction Patients 他达拉非对勃起功能障碍患者阴茎双相参数的影响
Pub Date : 2023-07-01 DOI: 10.21608/svuijm.2023.204013.1562
A. Younis, Mohamed Amer Ahmed Abdellatif, M. A. Ali, Mohammed Abu El-Hamd Ali, A. M. El-Ebidi, Salah Mohamed Ali Maklad, Essam A. Nada, M. E. El Taieb
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引用次数: 1
Immunohistochemical Expression of Estrogen Receptor Beta in Urothelial Carcinoma of the Urinary Bladder 雌激素受体β在膀胱尿路上皮癌中的免疫组织化学表达
Pub Date : 2023-07-01 DOI: 10.21608/svuijm.2022.160639.1403
Omnia M. Badawy, Sabah Ahmed Mohamed, A. Hassan, Ghada Mohamed
Background: The tenth most prevalent cancer type in the world is bladder cancer. Males are four times more likely than females to have it. The most prevalent subtype is urothelial carcinoma. Development and progression of bladder cancer are influenced by estrogen receptors. Objectives: To examine the expression of estrogen receptor beta in bladder urothelial carcinoma and how it relates to other pathological factors of prognostic significance. Materials and method: Fifty formalin fixed and paraffin-embedded tissue sections of cases of urothelial carcinoma from transurethral resection and radical cystectomy specimens were examined histopathologically by routine H&E stain and immunohistochemically stained with Anti-ER-beta antibody. The immunohistochemical expression of estrogen receptor beta was assessed. Results: Of the 50 cases of urothelial carcinoma, mean age 60 ±8.7 range (41-85) years, 34 male and 16 female, estrogen receptor beta was expressed in 29 (58%) of the cases. The expression of ERβ was significantly elevated in high grade (p value 0.006). The ERβ expression was also significantly increased in advanced tumor stages (p value 0.03) and in muscle invasive tumor (p value 0.004). The presence of lymphovascular emboli was associated with higher ERβexpression. Conclusion: ERβ expression is significantly associated with high grade and with advanced stages of urothelial carcinoma.
背景:膀胱癌是世界上第十大常见的癌症类型。男性患此病的可能性是女性的四倍。最常见的亚型是尿路上皮癌。膀胱癌的发生发展受雌激素受体的影响。目的:探讨雌激素受体β在膀胱尿路上皮癌中的表达及其与预后的关系。材料与方法:采用常规H&E染色和抗er - β抗体免疫组织化学染色,对经尿道膀胱切除术和根治性膀胱切除术的50例尿路上皮癌标本进行组织病理学检查。评估雌激素受体β的免疫组织化学表达。结果:50例尿路上皮癌患者,平均年龄60±8.7岁(41 ~ 85)岁,男性34例,女性16例,其中雌激素受体β表达29例(58%)。高分级ERβ表达明显升高(p值0.006)。ERβ的表达在肿瘤晚期(p值0.03)和肌肉浸润性肿瘤中也显著升高(p值0.004)。淋巴血管栓塞的存在与较高的er β表达有关。结论:ERβ的表达与高分级和晚期尿路上皮癌有显著相关性。
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引用次数: 0
Bacteriological Profile and Antibiotic Resistance Pattern of Pathogens Causing Pyogenic Infections At A Tertiary Care Hospital in Central India 在印度中部的一家三级保健医院引起化脓性感染的病原体的细菌学概况和抗生素耐药性模式
Pub Date : 2023-07-01 DOI: 10.21608/svuijm.2023.179653.1468
M. Diwakar, A. Mehta, R. Pratap
Background : Pyogenic infection is a bacterial infection that leads to the formation of pus. Antibiotics are routinely prescribed to treat these pyogenic bacterial infections, but their toxicity poses a severe threat. It is important to know the antimicrobial resistance profile of such pathogens for proper management of the patients. Objectives: To determine the bacteriological profile and antibiotic resistance pattern of pyogens. Patients and Methods: In this cross sectional study, a total of 678 pus samples were received and processed for aerobic culture from various departments. Standard techniques were used to identify isolates from positive pus cultures, and CLSI standards were used to identify antimicrobial susceptibility patterns. Results: Out of the 678 samples, 347 (51.18%) showed growth of pathogenic bacteria. Two hundred seventeen two (40.11%) Gram positive cocci and 75 (11.06%) Gram negative bacilli isolates were identified. Staphylococcus aureus was the most common isolate (57.5%). Most of the isolates were highly resistant to commonly prescribed antimicrobial drugs like Amoxycillin clavulanate. Most of the gram positive isolates were susceptible to vancomycin, linezolid, and teicoplanin. Most of the Gram-negative isolates were sensitive to imipenem. Conclusion: Microbiological profile findings of pus culture isolates as well as their pattern of antimicrobial resistant may aid in the formulation of antibiotic policies for pyogenic infections.
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引用次数: 0
Biomarkers for prediction of acute kidney injury after Cardiac and Non-cardiac Elective Surgeries: A comparative observational study 预测心脏和非心脏选择性手术后急性肾损伤的生物标志物:一项比较观察研究
Pub Date : 2023-07-01 DOI: 10.21608/svuijm.2023.194275.1527
{"title":"Biomarkers for prediction of acute kidney injury after Cardiac and Non-cardiac Elective Surgeries: A comparative observational study","authors":"","doi":"10.21608/svuijm.2023.194275.1527","DOIUrl":"https://doi.org/10.21608/svuijm.2023.194275.1527","url":null,"abstract":"","PeriodicalId":34789,"journal":{"name":"SVU International Journal of Medical Sciences","volume":"67 3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77643841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
SVU International Journal of Medical Sciences
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