A. Fatoni, Mauizatul Hasanah, Lasmaryna Sirumapea, Annisa Defanie Putri, Khoirunnisa Sari, Restu Dwi Khairani, N. Hidayati
The polyvinyl alcohol-chitosan-ZnO/CuO nanoparticles film was researched. Synthesis, characterization, and its biological evaluation as an antibacterial of Staphylococcus aureus were the aims of this research. The biosynthesis of ZnO, CuO, and ZnO/CuO nanoparticles was done using the biological method. The polyvinyl alcohol-chitosan-ZnO/CuO nanoparticles film was synthesized using the casting method. All the products were characterized by FTIR spectroscopy, X-ray diffraction, and Scanning Electron Microscope (SEM). Polyvinyl alcohol-chitosan-ZnO/CuO nanoparticles film as a paper disk for the evaluation as an antibacterial agent through the agar disk diffusion method. The absorption bands of ZnO, CuO, and ZnO/CuO nanoparticles can be observed at 318, 274, and 252 nm, respectively. The peaks at wavenumbers 433-673 and 619 cm-1 were Zn-O and Cu-O groups, respectively. The Zn-O and Cu-O groups at ZnO/CuO nanoparticles can be observed at 474 and 619 cm-1. The appearance of Zn-O and Cu-O groups at film PVA-chitosan-ZnO/CuO nanoparticles indicates the wavenumber between 433 and 673 cm-1. The physical structure of ZnO, CuO, and ZnO/CuO nanoparticles is crystalline form. The crystallite size of ZnO, CuO, and ZnO/CuO nanoparticles was estimated at 1.0572, 6.6315, and 2.3333 nm respectively. The physical structure of film PVA-chitosan-ZnO/CuO nanoparticles is amorphous. The surface morphology of films C, D, and E was affected by the addition of chitosan and ZnO/CuO nanoparticles. The film of PVA-chitosan-ZnO/CuO nanoparticles (C, D and E) can act as an antibaterial agent of Staphylococcus aureus.The inhibition zone of film D is higher than A, B, C, and E.
{"title":"Synthesis, Characterization of Polyvinyl Alcohol-Chitosan-ZnO/CuO Nanoparticles Film and Its Biological Evaluation as An Antibacterial Agent of Staphylococcus aureus","authors":"A. Fatoni, Mauizatul Hasanah, Lasmaryna Sirumapea, Annisa Defanie Putri, Khoirunnisa Sari, Restu Dwi Khairani, N. Hidayati","doi":"10.15575/ak.v10i1.24725","DOIUrl":"https://doi.org/10.15575/ak.v10i1.24725","url":null,"abstract":"The polyvinyl alcohol-chitosan-ZnO/CuO nanoparticles film was researched. Synthesis, characterization, and its biological evaluation as an antibacterial of Staphylococcus aureus were the aims of this research. The biosynthesis of ZnO, CuO, and ZnO/CuO nanoparticles was done using the biological method. The polyvinyl alcohol-chitosan-ZnO/CuO nanoparticles film was synthesized using the casting method. All the products were characterized by FTIR spectroscopy, X-ray diffraction, and Scanning Electron Microscope (SEM). Polyvinyl alcohol-chitosan-ZnO/CuO nanoparticles film as a paper disk for the evaluation as an antibacterial agent through the agar disk diffusion method. The absorption bands of ZnO, CuO, and ZnO/CuO nanoparticles can be observed at 318, 274, and 252 nm, respectively. The peaks at wavenumbers 433-673 and 619 cm-1 were Zn-O and Cu-O groups, respectively. The Zn-O and Cu-O groups at ZnO/CuO nanoparticles can be observed at 474 and 619 cm-1. The appearance of Zn-O and Cu-O groups at film PVA-chitosan-ZnO/CuO nanoparticles indicates the wavenumber between 433 and 673 cm-1. The physical structure of ZnO, CuO, and ZnO/CuO nanoparticles is crystalline form. The crystallite size of ZnO, CuO, and ZnO/CuO nanoparticles was estimated at 1.0572, 6.6315, and 2.3333 nm respectively. The physical structure of film PVA-chitosan-ZnO/CuO nanoparticles is amorphous. The surface morphology of films C, D, and E was affected by the addition of chitosan and ZnO/CuO nanoparticles. The film of PVA-chitosan-ZnO/CuO nanoparticles (C, D and E) can act as an antibaterial agent of Staphylococcus aureus.The inhibition zone of film D is higher than A, B, C, and E.","PeriodicalId":34816,"journal":{"name":"AlKimiya Jurnal Ilmu Kimia dan Terapan","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46343663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
F. S. Irwansyah, Alfi Ikhlasul Amal, E. P. Hadisantoso, A. Noviyanti, D. Eddy, Azman Ma'amor, Risdiana Risdiana
Hydroxyapatite (HA) was successfully synthesized using the hydrothermal method. This study aimed to analyze the effect of a low solid/liquid ratio on the properties of HA crystals. HA synthesis was performed using chicken eggshells and the hydrothermal method at a temperature of 150°C. The solvent amount was kept constant, while the solid amount varied (half-reaction). The characteristics of HA were determined using XRD, FTIR, PSA, and SEM. The results showed that the purity and size of HA were influenced by a low solid/liquid ratio, while the crystallinity remained relatively unchanged, directly impacting the lattice parameter value. FTIR analysis revealed the absence of the O-H group in the sample with the low solid/liquid ratio. PSA results showed a smaller particle size of 0.995 µm for the sample with the low solid/liquid ratio. SEM results demonstrated a smaller particle size in the sample with a low solid/liquid ratio when observed at the same magnification
{"title":"Effect of Low Solid/Liquid Ratio on Hydrothermal Synthesis of Hydroxyapatite with Green Template from Banana Flower (Musa acuminata Cavendish)","authors":"F. S. Irwansyah, Alfi Ikhlasul Amal, E. P. Hadisantoso, A. Noviyanti, D. Eddy, Azman Ma'amor, Risdiana Risdiana","doi":"10.15575/ak.v10i1.25262","DOIUrl":"https://doi.org/10.15575/ak.v10i1.25262","url":null,"abstract":"Hydroxyapatite (HA) was successfully synthesized using the hydrothermal method. This study aimed to analyze the effect of a low solid/liquid ratio on the properties of HA crystals. HA synthesis was performed using chicken eggshells and the hydrothermal method at a temperature of 150°C. The solvent amount was kept constant, while the solid amount varied (half-reaction). The characteristics of HA were determined using XRD, FTIR, PSA, and SEM. The results showed that the purity and size of HA were influenced by a low solid/liquid ratio, while the crystallinity remained relatively unchanged, directly impacting the lattice parameter value. FTIR analysis revealed the absence of the O-H group in the sample with the low solid/liquid ratio. PSA results showed a smaller particle size of 0.995 µm for the sample with the low solid/liquid ratio. SEM results demonstrated a smaller particle size in the sample with a low solid/liquid ratio when observed at the same magnification","PeriodicalId":34816,"journal":{"name":"AlKimiya Jurnal Ilmu Kimia dan Terapan","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42335500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
La Ode Sumarlin, A. Suprayogi, M. Rahminiwati, A. Satyaningtijas, H. Hajar, Meyliana Wulandari
Various treatments for Type 2 Diabetes Mellitus (T2DM) aim to alleviate hyperglycemia. Although natural products have been extensively utilized, their mechanism of action and efficacy as antidiabetic agents, particularly for T2DM, has not been extensively assessed in vivo. In this research, the leaves of the Namnam (Cynometra cauliflora) were extracted and tested for their activity as an antidiabetic agent. Sprague Dawley rats aged 3.5-4 months, weighing 200-250 g, were used as the experimental model, with a total of 30 individuals. The rats were induced with a high-fat diet and 30% sucrose until their blood glucose concentration reached ≥ 120 mg/dL. Subsequently, the rats were divided into four groups (groups 1, 2, 3, and 4). Over 21 days, changes in blood glucose, triacylglycerol, glycogen, and blood plasma insulin levels were assessed. The results demonstrated that the methanol extract of Namnam leaves (NLME) effectively reduced blood glucose levels by 23-34%, decreased plasma triglyceride levels by 13-30%, and increased liver glycogen levels by 68-96% compared to the control group (Diabetes). Among all the parameters assessed, NLME exhibited similar performance to metformin, a commonly prescribed diabetes medication (p<0.05). Furthermore, the study revealed that NLME exerted antidiabetic effects, particularly for T2DM, by promoting liver glycogen formation, enhancing insulin secretion control, facilitating glucose absorption by muscles, and restricting fat metabolism in the blood
{"title":"Studi of In Vivo Antidiabetic Activity of Namnam Leaves (Cynometra cauliflora) Extract in Sprague Dawley Rat","authors":"La Ode Sumarlin, A. Suprayogi, M. Rahminiwati, A. Satyaningtijas, H. Hajar, Meyliana Wulandari","doi":"10.15575/ak.v10i1.23406","DOIUrl":"https://doi.org/10.15575/ak.v10i1.23406","url":null,"abstract":"Various treatments for Type 2 Diabetes Mellitus (T2DM) aim to alleviate hyperglycemia. Although natural products have been extensively utilized, their mechanism of action and efficacy as antidiabetic agents, particularly for T2DM, has not been extensively assessed in vivo. In this research, the leaves of the Namnam (Cynometra cauliflora) were extracted and tested for their activity as an antidiabetic agent. Sprague Dawley rats aged 3.5-4 months, weighing 200-250 g, were used as the experimental model, with a total of 30 individuals. The rats were induced with a high-fat diet and 30% sucrose until their blood glucose concentration reached ≥ 120 mg/dL. Subsequently, the rats were divided into four groups (groups 1, 2, 3, and 4). Over 21 days, changes in blood glucose, triacylglycerol, glycogen, and blood plasma insulin levels were assessed. The results demonstrated that the methanol extract of Namnam leaves (NLME) effectively reduced blood glucose levels by 23-34%, decreased plasma triglyceride levels by 13-30%, and increased liver glycogen levels by 68-96% compared to the control group (Diabetes). Among all the parameters assessed, NLME exhibited similar performance to metformin, a commonly prescribed diabetes medication (p<0.05). Furthermore, the study revealed that NLME exerted antidiabetic effects, particularly for T2DM, by promoting liver glycogen formation, enhancing insulin secretion control, facilitating glucose absorption by muscles, and restricting fat metabolism in the blood","PeriodicalId":34816,"journal":{"name":"AlKimiya Jurnal Ilmu Kimia dan Terapan","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43992987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sappana (Caesalpinnia sappan L.) has been known as a natural dye in textiles and food. This research aimed to develop a sappan-based natural dye for fabrics dyeing by SiO2 modification as the UV protection agent. The sappan dye and its color were measured by colorimetric methods on UV-Vis spectrophotometry. The testing of the material includes a standard color detection test on the solution and washing resistance on cotton fabrics. The product is the prototype of a stable natural dye product of SiO2 modified - sappan (Si-Cs) which will be performed consistently on cotton fabrics. The result showed that SiO2-modified sappan dye had a higher absorbance in UV-Vis Spectrometer. The performance of the coloring product was also better than the standard sappan dye, indicated by the higher Ultraviolet Protection Factor and the fastness value. Variations of coloring products affected by the mordant agents varied from orange-red-purple caused by non-mordant–alum acetate and iron mordant respectively.
{"title":"Silica Modified Natural Dye of Caesalpinnia sappan l. on Cotton Fabrics","authors":"K. Budiasih, E. Rohaeti, Isti Yunita, A. Kamari","doi":"10.15575/ak.v10i1.24578","DOIUrl":"https://doi.org/10.15575/ak.v10i1.24578","url":null,"abstract":"Sappana (Caesalpinnia sappan L.) has been known as a natural dye in textiles and food. This research aimed to develop a sappan-based natural dye for fabrics dyeing by SiO2 modification as the UV protection agent. The sappan dye and its color were measured by colorimetric methods on UV-Vis spectrophotometry. The testing of the material includes a standard color detection test on the solution and washing resistance on cotton fabrics. The product is the prototype of a stable natural dye product of SiO2 modified - sappan (Si-Cs) which will be performed consistently on cotton fabrics. The result showed that SiO2-modified sappan dye had a higher absorbance in UV-Vis Spectrometer. The performance of the coloring product was also better than the standard sappan dye, indicated by the higher Ultraviolet Protection Factor and the fastness value. Variations of coloring products affected by the mordant agents varied from orange-red-purple caused by non-mordant–alum acetate and iron mordant respectively.","PeriodicalId":34816,"journal":{"name":"AlKimiya Jurnal Ilmu Kimia dan Terapan","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48403751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Sapar, Millenia Millenia, A. B. Aritonang, R. Rudiyansyah, W. Rahmalia
Characterization of secondary metabolites and cytotoxic testing of Haliclona sp. against T47D breast cancer cells were conducted in this study. The objective was to assess the cytotoxicity of T47D cancer cells and identify the functional groups involved. The research methods employed included maceration, partitioning, phytochemical testing, toxicity testing using the BSLT method, separation through flash column chromatography (FCC), cytotoxic testing using the MTT method, and characterization using FTIR. The partition results of methanol extract consist of n-hexane, ethyl acetate, and methanol-water fractions. The methanol extract demonstrated high toxicity, with an LC50 of 5.21 ppm. Among the fractions, the ethyl acetate fraction exhibited the highest toxicity compared to the n-hexane and methanol-water fractions, with LC50 values of 25.76 ppm, 42.71 ppm, and 55.26 ppm, respectively. Phytochemical testing of the ethyl acetate fraction yielded positive results for terpenoids, steroids, alkaloids, and phenolic compounds. The ethyl acetate fraction was further separated using flash column chromatography, resulting in ten combined fractions (M1-M10). The cytotoxicity tests of the M3 fraction against 747D breast cancer cells showed non-toxic effects, with an IC50 value of 1382.29 ppm. The FTIR analysis of the M3 fraction revealed the presence of functional groups such as O-H, =C-H, C-H aliphatic, C=O, and C=C, which is indicative of the presence of terpenoids, steroids, and esters.
{"title":"Characterization of Secondary Metabolites and Cytotoxic Assay of Haliclona sp. Sponge Against T47D Breast Cancer Cells","authors":"A. Sapar, Millenia Millenia, A. B. Aritonang, R. Rudiyansyah, W. Rahmalia","doi":"10.15575/ak.v10i1.20334","DOIUrl":"https://doi.org/10.15575/ak.v10i1.20334","url":null,"abstract":"Characterization of secondary metabolites and cytotoxic testing of Haliclona sp. against T47D breast cancer cells were conducted in this study. The objective was to assess the cytotoxicity of T47D cancer cells and identify the functional groups involved. The research methods employed included maceration, partitioning, phytochemical testing, toxicity testing using the BSLT method, separation through flash column chromatography (FCC), cytotoxic testing using the MTT method, and characterization using FTIR. The partition results of methanol extract consist of n-hexane, ethyl acetate, and methanol-water fractions. The methanol extract demonstrated high toxicity, with an LC50 of 5.21 ppm. Among the fractions, the ethyl acetate fraction exhibited the highest toxicity compared to the n-hexane and methanol-water fractions, with LC50 values of 25.76 ppm, 42.71 ppm, and 55.26 ppm, respectively. Phytochemical testing of the ethyl acetate fraction yielded positive results for terpenoids, steroids, alkaloids, and phenolic compounds. The ethyl acetate fraction was further separated using flash column chromatography, resulting in ten combined fractions (M1-M10). The cytotoxicity tests of the M3 fraction against 747D breast cancer cells showed non-toxic effects, with an IC50 value of 1382.29 ppm. The FTIR analysis of the M3 fraction revealed the presence of functional groups such as O-H, =C-H, C-H aliphatic, C=O, and C=C, which is indicative of the presence of terpenoids, steroids, and esters.","PeriodicalId":34816,"journal":{"name":"AlKimiya Jurnal Ilmu Kimia dan Terapan","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41378844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chalcone analogues (1-(1-naphthyl)-5-phenyl-2,4-pentadiene-1-one) have been synthesized through an aldol condensation reaction between cinnamaldehyde and 1-acetylnaphthalene. The method used in this study is the stirrer method, with the reaction conducted at room temperature for 24 hours using a NaOH catalyst in H2O/ethanol (50%, v/v). The purity of the product was analyzed using thin-layer chromatography on silica gel plates with n-hexane: ethyl acetate (9:1) employed as the solvent. The resulting product obtained was 0.88 g with a yield of 61.97%. Structure Analysis and elucidation of the synthesized compounds were performed by measuring the vibrations of the functional groups using FTIR, LCMSMS analysis, and determining the 1H and 13C atoms by HNMR and CNMR analysis. The FTIR, LCMSMS, 1H, and 13C NMR analysis identified that the synthesized product as chalcone analogues, specifically 1-(1-naphthyl)-5-phenyl-2,4-pentadiene-1-one.
{"title":"Synthesis and Characterization of 1-(1-naphthyl)-5-phenyl-2,4-pentadien-1-one from trans-cinnamaldehyde and 1-acetonaphthone","authors":"Dori Fitria, B. Ardiansah, Atia Balkis","doi":"10.15575/ak.v10i1.22896","DOIUrl":"https://doi.org/10.15575/ak.v10i1.22896","url":null,"abstract":"Chalcone analogues (1-(1-naphthyl)-5-phenyl-2,4-pentadiene-1-one) have been synthesized through an aldol condensation reaction between cinnamaldehyde and 1-acetylnaphthalene. The method used in this study is the stirrer method, with the reaction conducted at room temperature for 24 hours using a NaOH catalyst in H2O/ethanol (50%, v/v). The purity of the product was analyzed using thin-layer chromatography on silica gel plates with n-hexane: ethyl acetate (9:1) employed as the solvent. The resulting product obtained was 0.88 g with a yield of 61.97%. Structure Analysis and elucidation of the synthesized compounds were performed by measuring the vibrations of the functional groups using FTIR, LCMSMS analysis, and determining the 1H and 13C atoms by HNMR and CNMR analysis. The FTIR, LCMSMS, 1H, and 13C NMR analysis identified that the synthesized product as chalcone analogues, specifically 1-(1-naphthyl)-5-phenyl-2,4-pentadiene-1-one.","PeriodicalId":34816,"journal":{"name":"AlKimiya Jurnal Ilmu Kimia dan Terapan","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42031099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Safni Safni, Eno Okta Patricia, Trisna Ollinovela, Yulizar Yusuf
This study focuses on the degradation of phenol in aqueous solutions using photolysis and sonolysis methods. It investigates the impact of catalyst mass, types of light (UV-A, UV-C, and visible light), types of catalyst (RHAC, TiO2, and TiO2/RHAC), and processing time on phenol degradation. The phenol solutions are analyzed before and after degradation using Spectrophotometer UV-Vis and HPLC. The research aims to understand the factors influencing phenol degradation and provide a basis for further studies to enhance the efficiency of phenol removal. Results show significant improvements in degradation percentages of phenol by using TiO2/RHAC as the catalyst. Sonolysis achieves a degradation of 20.82% with a catalyst, which increases to 50.57% with the catalyst. Photolysis achieves a degradation of 29.06%, which rises to 91.99% with the catalyst. The highest degradation percentage is achieved using UV-A light for 5 hours with a catalyst mass of 30 mg of TiO2/RHAC catalyst. HPLC analysis confirms a decreased phenol concentration and the presence of intermediate compounds. The TiO2/RHAC catalyst demonstrates the promising potential for efficient phenol degradation in aqueous solutions.
{"title":"Degradation of Phenol Using Sonolysis and Photolysis by TiO2/RHAC Catalyst and Analysis with Spectrophotometer UV-VIS and HPLC","authors":"Safni Safni, Eno Okta Patricia, Trisna Ollinovela, Yulizar Yusuf","doi":"10.15575/ak.v10i1.24775","DOIUrl":"https://doi.org/10.15575/ak.v10i1.24775","url":null,"abstract":"This study focuses on the degradation of phenol in aqueous solutions using photolysis and sonolysis methods. It investigates the impact of catalyst mass, types of light (UV-A, UV-C, and visible light), types of catalyst (RHAC, TiO2, and TiO2/RHAC), and processing time on phenol degradation. The phenol solutions are analyzed before and after degradation using Spectrophotometer UV-Vis and HPLC. The research aims to understand the factors influencing phenol degradation and provide a basis for further studies to enhance the efficiency of phenol removal. Results show significant improvements in degradation percentages of phenol by using TiO2/RHAC as the catalyst. Sonolysis achieves a degradation of 20.82% with a catalyst, which increases to 50.57% with the catalyst. Photolysis achieves a degradation of 29.06%, which rises to 91.99% with the catalyst. The highest degradation percentage is achieved using UV-A light for 5 hours with a catalyst mass of 30 mg of TiO2/RHAC catalyst. HPLC analysis confirms a decreased phenol concentration and the presence of intermediate compounds. The TiO2/RHAC catalyst demonstrates the promising potential for efficient phenol degradation in aqueous solutions.","PeriodicalId":34816,"journal":{"name":"AlKimiya Jurnal Ilmu Kimia dan Terapan","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41489959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R. Bemis, R. D. Puspitasari, Heriyanti Heriyanti, R. Rahmi, Gessy Tri Priyanti
Hydroxyapatite (HA) is an alloplastic material that is commonly used as a substitute for bone grafts or bone grafts because it has bioactive properties, namely osteoconduction. This study aims to improve or develop the function of hydroxyapatite to become a strong and resilient biological device that can withstand loads for appropriate functions such as bone implants. Therefore, it is necessary to modify the structure, among others, by the reinforcement process (composite formation) with other materials.The doping of hydroxyapatite/Al2O3 in this study was carried out using the hydrothermal method. The hydrothermal method is one of the hydroxyapatite synthesis methods carried out at high pressure and temperature to achieve equilibrium. The material used in this study was papai shrimp as a source of calcium. The temperature has an effect in this study where the higher the doping temperature used, the higher the degree of crystallinity, particle size homogeneity, and porosity value. From the doping results, it is known that a temperature of 300°C produces a degree of crystallinity of 54.32% and a crystal size of 3.75 nm with a porosity value of 99.38%. This result is much better than the undoped hydroxyapatite in the previous study.
{"title":"The Effect of Variations of Hydrothermal Temperatures on Ex-Situ Hydroxyapatite/Al2O3 Doping Process from Papai Shrimp (Acetes erythraeus)","authors":"R. Bemis, R. D. Puspitasari, Heriyanti Heriyanti, R. Rahmi, Gessy Tri Priyanti","doi":"10.15575/ak.v9i2.20520","DOIUrl":"https://doi.org/10.15575/ak.v9i2.20520","url":null,"abstract":"Hydroxyapatite (HA) is an alloplastic material that is commonly used as a substitute for bone grafts or bone grafts because it has bioactive properties, namely osteoconduction. This study aims to improve or develop the function of hydroxyapatite to become a strong and resilient biological device that can withstand loads for appropriate functions such as bone implants. Therefore, it is necessary to modify the structure, among others, by the reinforcement process (composite formation) with other materials.The doping of hydroxyapatite/Al2O3 in this study was carried out using the hydrothermal method. The hydrothermal method is one of the hydroxyapatite synthesis methods carried out at high pressure and temperature to achieve equilibrium. The material used in this study was papai shrimp as a source of calcium. The temperature has an effect in this study where the higher the doping temperature used, the higher the degree of crystallinity, particle size homogeneity, and porosity value. From the doping results, it is known that a temperature of 300°C produces a degree of crystallinity of 54.32% and a crystal size of 3.75 nm with a porosity value of 99.38%. This result is much better than the undoped hydroxyapatite in the previous study.","PeriodicalId":34816,"journal":{"name":"AlKimiya Jurnal Ilmu Kimia dan Terapan","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49218858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Awaly Ilham Dewantoro, S. Putri, E. Mardawati, Desy Nurliasari
Various weeds in paddy rice fields could be utilized as natural polyphenols sources, one of them was kitolod (Hippobroma longiflora (L.) G.Don). Kitolod was widely utilized as traditional medicine by several community groups because of its polyphenols content. Recent trends showed kitolod could be valorized as additive matters in sunscreen products. Polyphenols content, especially flavonoids were able to absorb dangerous spectrum in sunray radiation and it is related to sunscreen activity. This study aimed to evaluate the differences in simplicia treatments and extraction techniques towards total polyphenols content and sunscreen activity on kitolod leaf extracts. Solvent-cold extraction techniques were deployed in this study that consist of water infusion and ethanolic maceration for 24 hours at ambient temperature. Extracts were analyzed by spectrophotometric measurement to determine total phenolics content (TPC), total flavonoids content (TFC), and sunscreen activity by deploying Folin-Ciocalteu assay, AlCl3 colorimetric assay, and Mansur approached assay, respectively. Dry kitolod leaves were extracted by ethanolic maceration techniques provided high yields (15.5±0.3%), high TPC (17.9±0.3 mg GAE/g of solids), high TFC (25.9±0.4 mg QE/g of solids), and moderate sunscreen activity (SPF 11.0±0.1). The results indicated kitolod could be valorized as natural polyphenols sources and additive matters in any cosmetical sunscreen products.
{"title":"Sunscreen Activity Determination on Hippobroma Longiflora Leaves Extracts Affected to Differences in Simplicia Treatments and Extraction Techniques","authors":"Awaly Ilham Dewantoro, S. Putri, E. Mardawati, Desy Nurliasari","doi":"10.15575/ak.v9i2.20502","DOIUrl":"https://doi.org/10.15575/ak.v9i2.20502","url":null,"abstract":"Various weeds in paddy rice fields could be utilized as natural polyphenols sources, one of them was kitolod (Hippobroma longiflora (L.) G.Don). Kitolod was widely utilized as traditional medicine by several community groups because of its polyphenols content. Recent trends showed kitolod could be valorized as additive matters in sunscreen products. Polyphenols content, especially flavonoids were able to absorb dangerous spectrum in sunray radiation and it is related to sunscreen activity. This study aimed to evaluate the differences in simplicia treatments and extraction techniques towards total polyphenols content and sunscreen activity on kitolod leaf extracts. Solvent-cold extraction techniques were deployed in this study that consist of water infusion and ethanolic maceration for 24 hours at ambient temperature. Extracts were analyzed by spectrophotometric measurement to determine total phenolics content (TPC), total flavonoids content (TFC), and sunscreen activity by deploying Folin-Ciocalteu assay, AlCl3 colorimetric assay, and Mansur approached assay, respectively. Dry kitolod leaves were extracted by ethanolic maceration techniques provided high yields (15.5±0.3%), high TPC (17.9±0.3 mg GAE/g of solids), high TFC (25.9±0.4 mg QE/g of solids), and moderate sunscreen activity (SPF 11.0±0.1). The results indicated kitolod could be valorized as natural polyphenols sources and additive matters in any cosmetical sunscreen products.","PeriodicalId":34816,"journal":{"name":"AlKimiya Jurnal Ilmu Kimia dan Terapan","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43452334","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The increasing consumption of electrical energy and still dependent on non-renewable energy has encouraged the implementation of effective, efficient, and environmentally friendly technologies to produce electrical energy. Microbial Fuel Cell (MFC) is one of the alternative technologies that utilize microorganisms in converting chemical energy from organic compounds under anaerobic conditions to be converted into electrical energy. The study was conducted to determine the potential of electrical energy generated from the treatment of eceng gondok waste (Eichhornia crassipes) with variations in the addition of buffer solutions and combinations of electrolyte solutions using the microorganism Saccharomyces cerevisiae through Microbial Fuel Cell technology. This study consists of three stages and methods, namely sample preparation, MFC media preparation, and analysis of pH, current, voltage, and power density. Measurement of the value of the maximum voltage, maximum current and power density is carried out every 3 hours for 27 hours for each treatment. The results were obtained as follows consecutively: firstly, for variations without the addition of buffers and electrolyte solutions are 0.25 volts; 0.08 mA; 13.05 mW/m2, secondly, with buffer and electrolyte solution KMnO4 0.2 M are 1.12 volts; 0.77 mA; 562.92 mW/m2, and thirdly, with buffer and K3Fe(CN)6 0.2 M are 0.47 volts; 0.48 mA; 147.26 mW/m2. Based on the results of the study, it was concluded that the most optimal variation in producing electrical energy was in the variation in the addition of a phosphate buffer and 0.2 M KMnO4 solution. Eceng gondok waste has the potential to be used as a source of electrical energy.
{"title":"Treatment of Eceng Gondok Waste into Electrical Based on Microbial Fuel Cell","authors":"Hijrah Amaliah Azis, Ardiansa Ardiansa, Riki Kusuma Purnama","doi":"10.15575/ak.v9i2.20974","DOIUrl":"https://doi.org/10.15575/ak.v9i2.20974","url":null,"abstract":"The increasing consumption of electrical energy and still dependent on non-renewable energy has encouraged the implementation of effective, efficient, and environmentally friendly technologies to produce electrical energy. Microbial Fuel Cell (MFC) is one of the alternative technologies that utilize microorganisms in converting chemical energy from organic compounds under anaerobic conditions to be converted into electrical energy. The study was conducted to determine the potential of electrical energy generated from the treatment of eceng gondok waste (Eichhornia crassipes) with variations in the addition of buffer solutions and combinations of electrolyte solutions using the microorganism Saccharomyces cerevisiae through Microbial Fuel Cell technology. This study consists of three stages and methods, namely sample preparation, MFC media preparation, and analysis of pH, current, voltage, and power density. Measurement of the value of the maximum voltage, maximum current and power density is carried out every 3 hours for 27 hours for each treatment. The results were obtained as follows consecutively: firstly, for variations without the addition of buffers and electrolyte solutions are 0.25 volts; 0.08 mA; 13.05 mW/m2, secondly, with buffer and electrolyte solution KMnO4 0.2 M are 1.12 volts; 0.77 mA; 562.92 mW/m2, and thirdly, with buffer and K3Fe(CN)6 0.2 M are 0.47 volts; 0.48 mA; 147.26 mW/m2. Based on the results of the study, it was concluded that the most optimal variation in producing electrical energy was in the variation in the addition of a phosphate buffer and 0.2 M KMnO4 solution. Eceng gondok waste has the potential to be used as a source of electrical energy.","PeriodicalId":34816,"journal":{"name":"AlKimiya Jurnal Ilmu Kimia dan Terapan","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42196847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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