Pub Date : 2011-04-19DOI: 10.1109/MECBME.2011.5752093
T. Kaufmann, K. Gester, K. V. von Trotha, N. Butz, U. Neumann, T. Schmitz-Rode, U. Steinseifer
Most surgical interventions require joining of soft tissue, and suturation is the most common approach. While high suture tension may result in ischemia or even necrosis, a loose structure holds the risk of hemorrhage of the wound edges, causing postoperative complications and a potential necessity for reoperation. Estimating and controlling the tension within the suture is therefore a crucial factor for suture stability and thus successful treatment. In this study a numerical evaluation of different fiber materials and puncture modalities is presented. In total, 120 combinations of fiber material and number and distance of punctures are compared in terms of maximum shear rates representing suture tension. The results indicate that Vicryl fibers provide lower suture tension compared to PDS, and that an increased number of punctures decreases suture tension. Results are in good agreement with experimental studies. The presented method can be used to analyze various suture techniques and thus help to achieve successful treatment.
{"title":"Numerical simulation of suture tension dependent on fiber material and puncture modalities","authors":"T. Kaufmann, K. Gester, K. V. von Trotha, N. Butz, U. Neumann, T. Schmitz-Rode, U. Steinseifer","doi":"10.1109/MECBME.2011.5752093","DOIUrl":"https://doi.org/10.1109/MECBME.2011.5752093","url":null,"abstract":"Most surgical interventions require joining of soft tissue, and suturation is the most common approach. While high suture tension may result in ischemia or even necrosis, a loose structure holds the risk of hemorrhage of the wound edges, causing postoperative complications and a potential necessity for reoperation. Estimating and controlling the tension within the suture is therefore a crucial factor for suture stability and thus successful treatment. In this study a numerical evaluation of different fiber materials and puncture modalities is presented. In total, 120 combinations of fiber material and number and distance of punctures are compared in terms of maximum shear rates representing suture tension. The results indicate that Vicryl fibers provide lower suture tension compared to PDS, and that an increased number of punctures decreases suture tension. Results are in good agreement with experimental studies. The presented method can be used to analyze various suture techniques and thus help to achieve successful treatment.","PeriodicalId":348448,"journal":{"name":"2011 1st Middle East Conference on Biomedical Engineering","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130108654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2011-04-19DOI: 10.1109/MECBME.2011.5752148
Mohamed Omar, Abdalla S. A. Mohamed
Patients with congestive heart failure (CHF)] have neurologic complications, and decreased pulmonary flow. This will lead to having nonstationary ECG signal and also its heart rate variability (HRV) signal. In this work, we used the empirical mode decomposition (EMD) to develop a strategy to identify the relevant intrinsic mode functions (IMFs) for classification. The data set includes long-term record (1-Hour) of ECG signals from normal and CHF. K-means clustering technique was used to classify the decomposed IMFs. The percentage of success of classification using ECG signal was 89% with the first four IMFs while with HRV signal was 100% with the first IMF.
{"title":"Application of the empirical mode decomposition to ECG and HRV signals for congestive heart failure classification","authors":"Mohamed Omar, Abdalla S. A. Mohamed","doi":"10.1109/MECBME.2011.5752148","DOIUrl":"https://doi.org/10.1109/MECBME.2011.5752148","url":null,"abstract":"Patients with congestive heart failure (CHF)] have neurologic complications, and decreased pulmonary flow. This will lead to having nonstationary ECG signal and also its heart rate variability (HRV) signal. In this work, we used the empirical mode decomposition (EMD) to develop a strategy to identify the relevant intrinsic mode functions (IMFs) for classification. The data set includes long-term record (1-Hour) of ECG signals from normal and CHF. K-means clustering technique was used to classify the decomposed IMFs. The percentage of success of classification using ECG signal was 89% with the first four IMFs while with HRV signal was 100% with the first IMF.","PeriodicalId":348448,"journal":{"name":"2011 1st Middle East Conference on Biomedical Engineering","volume":"34 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130149423","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2011-04-19DOI: 10.1109/MECBME.2011.5752061
L. Trabzon, M. Ramazanoglu, H. Kizil, S. Guvendik
We successfully engineered Si nano-columns with different cross-sectional geometries by e-beam evaporation with an angle between source and substrate. The Si nano-columns were grown as pillars with square, triangle and linear cross sections in in-plane. Mesenchymal stem cells (MSCs) isolated from the bone marrow stroma of young adult rats were cultured on these different Si nanosurfaces. We found that the behaviour of MSCs highly depended on the geometry of nano-topography so that mesenchymal stem cells were differentiated and induced CaP precipitation on square-cross-sectional Si nano-columns without growth factor in the culture medium.
{"title":"Mesenchymal stem cell differentiation by nano-engineered Si columns","authors":"L. Trabzon, M. Ramazanoglu, H. Kizil, S. Guvendik","doi":"10.1109/MECBME.2011.5752061","DOIUrl":"https://doi.org/10.1109/MECBME.2011.5752061","url":null,"abstract":"We successfully engineered Si nano-columns with different cross-sectional geometries by e-beam evaporation with an angle between source and substrate. The Si nano-columns were grown as pillars with square, triangle and linear cross sections in in-plane. Mesenchymal stem cells (MSCs) isolated from the bone marrow stroma of young adult rats were cultured on these different Si nanosurfaces. We found that the behaviour of MSCs highly depended on the geometry of nano-topography so that mesenchymal stem cells were differentiated and induced CaP precipitation on square-cross-sectional Si nano-columns without growth factor in the culture medium.","PeriodicalId":348448,"journal":{"name":"2011 1st Middle East Conference on Biomedical Engineering","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130225319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2011-04-19DOI: 10.1109/MECBME.2011.5752109
M. Hosseini, H. Soltanian-Zadeh, S. Akhlaghpoor
Chronic obstructive pulmonary disease (COPD) refers to a group of lung diseases that block airflow and cause a huge degree of human suffering. While there is no cure for COPD and the lung damage that results in this disease cannot be reversed, it is very important to diagnose it as early as possible. Additional to diagnosis, using a mathematical model to estimate severity of disease would be helpful for evaluation of treatment effects. This paper presents a new method for identifying COPD from three-dimensional (3-D) pulmonary X-ray CT images. The method has five main steps. First, corresponding positions of lungs in inspiration and expiration are found based on anatomical structures. Then, lung regions are segmented from the CT images by active contours. Next, the left and right lungs are separated using a sequence of morphological operations. Then, parenchyma variations in each lung are found as a relationship between inspiratory and expiratory states. Finally, a classifier is used to decide about the disease and its severity. A t-test is done to evaluate the results. Twelve patients with variable severity of COPD and twelve normal adults were included in this study. The proposed method may assist radiologists in the detection of COPD as a computer aided diagnosis (CAD) system.
{"title":"A novel method for identification of COPD in inspiratory and expiratory states of CT images","authors":"M. Hosseini, H. Soltanian-Zadeh, S. Akhlaghpoor","doi":"10.1109/MECBME.2011.5752109","DOIUrl":"https://doi.org/10.1109/MECBME.2011.5752109","url":null,"abstract":"Chronic obstructive pulmonary disease (COPD) refers to a group of lung diseases that block airflow and cause a huge degree of human suffering. While there is no cure for COPD and the lung damage that results in this disease cannot be reversed, it is very important to diagnose it as early as possible. Additional to diagnosis, using a mathematical model to estimate severity of disease would be helpful for evaluation of treatment effects. This paper presents a new method for identifying COPD from three-dimensional (3-D) pulmonary X-ray CT images. The method has five main steps. First, corresponding positions of lungs in inspiration and expiration are found based on anatomical structures. Then, lung regions are segmented from the CT images by active contours. Next, the left and right lungs are separated using a sequence of morphological operations. Then, parenchyma variations in each lung are found as a relationship between inspiratory and expiratory states. Finally, a classifier is used to decide about the disease and its severity. A t-test is done to evaluate the results. Twelve patients with variable severity of COPD and twelve normal adults were included in this study. The proposed method may assist radiologists in the detection of COPD as a computer aided diagnosis (CAD) system.","PeriodicalId":348448,"journal":{"name":"2011 1st Middle East Conference on Biomedical Engineering","volume":"44 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132722093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2011-04-19DOI: 10.1109/MECBME.2011.5752099
M. Najafi, Zahra Ghanbari, B. Molaee-Ardekani, M. Shamsollahi, T. Penzel
Sleep spindle is the hallmark of second stage of sleep in human being, which is defined as a rhythmic sequence with waxing and waning waves, whose frequency is approximately between 8 to 14 Hz, and its time duration is between 0.5 to 2 seconds. Bump modeling is a method for extracting regions with higher amounts of energy in a related time-frequency map. The bump model of the sleep spindle consists of a group of high energy bumps concentrating in approximately 8 to 14 Hz frequency band. In this study, it will be shown that the power of bumps of EEG can be used in automated detection of sleep spindle. The presented method sensitivity is 99.41% which shows high correctly detection rate, and its error detection ratio is 14.51%, which demonstrates the low dependency of the presented algorithm to the subjects, and its low false detection ratio.
{"title":"Sleep spindle detection in sleep EEG signal using sparse bump modeling","authors":"M. Najafi, Zahra Ghanbari, B. Molaee-Ardekani, M. Shamsollahi, T. Penzel","doi":"10.1109/MECBME.2011.5752099","DOIUrl":"https://doi.org/10.1109/MECBME.2011.5752099","url":null,"abstract":"Sleep spindle is the hallmark of second stage of sleep in human being, which is defined as a rhythmic sequence with waxing and waning waves, whose frequency is approximately between 8 to 14 Hz, and its time duration is between 0.5 to 2 seconds. Bump modeling is a method for extracting regions with higher amounts of energy in a related time-frequency map. The bump model of the sleep spindle consists of a group of high energy bumps concentrating in approximately 8 to 14 Hz frequency band. In this study, it will be shown that the power of bumps of EEG can be used in automated detection of sleep spindle. The presented method sensitivity is 99.41% which shows high correctly detection rate, and its error detection ratio is 14.51%, which demonstrates the low dependency of the presented algorithm to the subjects, and its low false detection ratio.","PeriodicalId":348448,"journal":{"name":"2011 1st Middle East Conference on Biomedical Engineering","volume":"48 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127243877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2011-04-19DOI: 10.1109/MECBME.2011.5752097
M. A. El-Nasr, H. Shaban, R. Buehrer
In this paper, we use our recently proposed highly accurate gait analysis system presented in [1] to measure the base-of-support (BOS) gait parameter, which is defined as the distance from heel-to-heel while walking. This particular gait parameter is known to be of clinical importance, and its measurement accuracy reported in the literature using current highly accurate optical tracking systems is not sufficiently accurate to be clinically accepted. We further develop a simulation environment using MATLAB to extract gait parameters from the raw-marker-data measured using sophisticated optical tracking systems, which commonly require dedicated and highly sophisticated software programs. Then, we compare the accuracy of the measured BOS using our proposed system to the extracted BOS from optical tracking systems. We show that our proposed system outperforms the corresponding highly accurate optical tracking systems. In particular, we show that our system provides an accuracy of 1.2% for the BOS measurement compared to 14.6% accuracy for current optical tracking systems.
{"title":"Measurement and extraction of base-of-support gait parameter using a novel accurate human locomotiontracking system via UWB radios","authors":"M. A. El-Nasr, H. Shaban, R. Buehrer","doi":"10.1109/MECBME.2011.5752097","DOIUrl":"https://doi.org/10.1109/MECBME.2011.5752097","url":null,"abstract":"In this paper, we use our recently proposed highly accurate gait analysis system presented in [1] to measure the base-of-support (BOS) gait parameter, which is defined as the distance from heel-to-heel while walking. This particular gait parameter is known to be of clinical importance, and its measurement accuracy reported in the literature using current highly accurate optical tracking systems is not sufficiently accurate to be clinically accepted. We further develop a simulation environment using MATLAB to extract gait parameters from the raw-marker-data measured using sophisticated optical tracking systems, which commonly require dedicated and highly sophisticated software programs. Then, we compare the accuracy of the measured BOS using our proposed system to the extracted BOS from optical tracking systems. We show that our proposed system outperforms the corresponding highly accurate optical tracking systems. In particular, we show that our system provides an accuracy of 1.2% for the BOS measurement compared to 14.6% accuracy for current optical tracking systems.","PeriodicalId":348448,"journal":{"name":"2011 1st Middle East Conference on Biomedical Engineering","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124337028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2011-04-19DOI: 10.1109/MECBME.2011.5752150
J. Alsuwaidi, H. Alawadhi, Ali Rahanjam, Mohamad Ahmed El Hallag, J. Janaczek, F. A. Kaabi, W. Al-Shamsi, Mohammad Abu Srour
The IAEA — UAE Project on Patient Radiation Protection aimed at evaluating radiation dose levels received by patients during radiological examinations. In this paper, we are presenting the preliminary results of patient doses in Computed Tomography (CT) examinations at 4 UAE hospitals (3 major governmental hospitals and 1 private). Five Multi-slice CT (MSCT) systems (4S, 16S and 64S) were included in this study. All these systems are enrolled in quality control program. CT dose levels were evaluated through either thermoluminescent detectors (TLD-100) or by using Head (16-cm Diameter) and Body (32-cm Diameter) cylindrical CTDI PMMA phantom fitted with a 10 cm pencil ionization chamber. Adult and pediatric patient CT doses were collected from common CT examinations of the Head, Chest and Abdomen & Pelvis. The CT Dose Index (CTDIvol), Dose Length Product (DLP) and Effective Doses (E) were the main CT dosimetry parameters evaluated in this project. The CTDIvol results of all CT systems showed acceptable compliance with those reported by professional organizations. The range of 3rd quartile of adult DLP values for CT Head examinations among the 4 hospitals was 384.106–5031.92 mGy.cm. The adult CT Chest examinations demonstrated the range of the 3rd quartile DLP values between 122.035–1423.06 mGy.cm while the Abdomen & Pelvis examinations showed a range of 258.446–1701.135 mGy.cm. Hospitals DD3, AA13 and ANM14 are within the UAE initial adapted local Dose Reference Levels (DRLs) and are comparable to the European guidelines while hospitals TA1 and TA2 are higher. The CT effective doses of almost all the examination types were within the level mentioned by international organizations such as the ICRP (Report 102, 2007) with the exception of CT examinations performed at TA1 & TA2. Further work is developed to reduce patient radiation doses of the common CT examinations of the Head, Chest and Abdomen & Pelvis. Adult and pediatric patient data collection and analysis of CT doses from other hospitals at the UAE are in progress.
{"title":"National survey on medical exposure to patients undergoing diagnostic radiology examinations: An initial overview on CT doses at UAE hospitals","authors":"J. Alsuwaidi, H. Alawadhi, Ali Rahanjam, Mohamad Ahmed El Hallag, J. Janaczek, F. A. Kaabi, W. Al-Shamsi, Mohammad Abu Srour","doi":"10.1109/MECBME.2011.5752150","DOIUrl":"https://doi.org/10.1109/MECBME.2011.5752150","url":null,"abstract":"The IAEA — UAE Project on Patient Radiation Protection aimed at evaluating radiation dose levels received by patients during radiological examinations. In this paper, we are presenting the preliminary results of patient doses in Computed Tomography (CT) examinations at 4 UAE hospitals (3 major governmental hospitals and 1 private). Five Multi-slice CT (MSCT) systems (4S, 16S and 64S) were included in this study. All these systems are enrolled in quality control program. CT dose levels were evaluated through either thermoluminescent detectors (TLD-100) or by using Head (16-cm Diameter) and Body (32-cm Diameter) cylindrical CTDI PMMA phantom fitted with a 10 cm pencil ionization chamber. Adult and pediatric patient CT doses were collected from common CT examinations of the Head, Chest and Abdomen & Pelvis. The CT Dose Index (CTDIvol), Dose Length Product (DLP) and Effective Doses (E) were the main CT dosimetry parameters evaluated in this project. The CTDIvol results of all CT systems showed acceptable compliance with those reported by professional organizations. The range of 3rd quartile of adult DLP values for CT Head examinations among the 4 hospitals was 384.106–5031.92 mGy.cm. The adult CT Chest examinations demonstrated the range of the 3rd quartile DLP values between 122.035–1423.06 mGy.cm while the Abdomen & Pelvis examinations showed a range of 258.446–1701.135 mGy.cm. Hospitals DD3, AA13 and ANM14 are within the UAE initial adapted local Dose Reference Levels (DRLs) and are comparable to the European guidelines while hospitals TA1 and TA2 are higher. The CT effective doses of almost all the examination types were within the level mentioned by international organizations such as the ICRP (Report 102, 2007) with the exception of CT examinations performed at TA1 & TA2. Further work is developed to reduce patient radiation doses of the common CT examinations of the Head, Chest and Abdomen & Pelvis. Adult and pediatric patient data collection and analysis of CT doses from other hospitals at the UAE are in progress.","PeriodicalId":348448,"journal":{"name":"2011 1st Middle East Conference on Biomedical Engineering","volume":"55 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114966042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Percutaneous heart valve replacement is an exciting and innovative technology which provides new treatment options for previously untreatable patients. Despite promising clinical results for the currently available prostheses by Edwards Lifesciences and Medtronic, these devices still require improvement in order to represent a true alternative to conventional heart valve replacement surgery. One of these challenges is the safe and effective anchoring of the catheter-delivered devices. This paper describes the development of an anchoring technique and highlights the key anatomical influence factors to be considered when designing percutaneous heart valve prostheses.
{"title":"Anchoring percutaneous heart valves","authors":"Maximilian Kutting, Ute Urban, U. Steinseifer","doi":"10.1166/JMIHI.2011.1038","DOIUrl":"https://doi.org/10.1166/JMIHI.2011.1038","url":null,"abstract":"Percutaneous heart valve replacement is an exciting and innovative technology which provides new treatment options for previously untreatable patients. Despite promising clinical results for the currently available prostheses by Edwards Lifesciences and Medtronic, these devices still require improvement in order to represent a true alternative to conventional heart valve replacement surgery. One of these challenges is the safe and effective anchoring of the catheter-delivered devices. This paper describes the development of an anchoring technique and highlights the key anatomical influence factors to be considered when designing percutaneous heart valve prostheses.","PeriodicalId":348448,"journal":{"name":"2011 1st Middle East Conference on Biomedical Engineering","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116171464","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2011-04-19DOI: 10.1109/MECBME.2011.5752123
G. J. Verkerke, P. Segers, K. Mottaghy, R. Reilly, V. Rogalewicz
For a single university it is difficult to have sufficient expertise of all sub-specialisations in biomedical engineering in order to provide 4th level education at an adequate level. Therefore a consortium of six universities has combined their knowledge and specific expertise into a 2-year European Master's in biomedical engineering: the Universities of Groningen (The Netherlands), Aachen (Germany), Dublin (Ireland), Ghent and Brussels (Belgium), Prague (Czech Republic). The Erasmus Mundus Master's course Common European MAster's Course in Biomedical Engineering (CEMACUBE) will prepare students from Europe and outside Europe for professions in biomedical engineering by giving them a Europan view and a broad solid foundation of the main topics of the field of biomedical engineering.
{"title":"CEMACUBE: The first European Master's course in biomedical engineering","authors":"G. J. Verkerke, P. Segers, K. Mottaghy, R. Reilly, V. Rogalewicz","doi":"10.1109/MECBME.2011.5752123","DOIUrl":"https://doi.org/10.1109/MECBME.2011.5752123","url":null,"abstract":"For a single university it is difficult to have sufficient expertise of all sub-specialisations in biomedical engineering in order to provide 4th level education at an adequate level. Therefore a consortium of six universities has combined their knowledge and specific expertise into a 2-year European Master's in biomedical engineering: the Universities of Groningen (The Netherlands), Aachen (Germany), Dublin (Ireland), Ghent and Brussels (Belgium), Prague (Czech Republic). The Erasmus Mundus Master's course Common European MAster's Course in Biomedical Engineering (CEMACUBE) will prepare students from Europe and outside Europe for professions in biomedical engineering by giving them a Europan view and a broad solid foundation of the main topics of the field of biomedical engineering.","PeriodicalId":348448,"journal":{"name":"2011 1st Middle East Conference on Biomedical Engineering","volume":"02 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129882008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2011-04-19DOI: 10.1109/MECBME.2011.5752094
M. Al-Fandi, M. Jaradat, M. Al-Rousan, S. Jaradat
In this paper, we experimentally investigated the navigation system of the nonpathogenic strain of E. coli (AW405) and developed a simulator for the locomotion performance of these swimming nanorobots. The swimming behavior of these cells is sensitive to the chemical gradients in their medium. Tissue and disease cells might produce chemical signals in their surroundings. These chemicals have the potential to affect the locomotion behavior of the bacterial cells. Therefore, bacterial cells can be considered as self-navigator nanorobots that are able to discriminate between disease cells such as cancer. Our current experimental and theoretical work is considered as a platform to this novel idea of early detection of problematic diseases.
{"title":"A living biological nano robot as self-navigator sensor for diseases","authors":"M. Al-Fandi, M. Jaradat, M. Al-Rousan, S. Jaradat","doi":"10.1109/MECBME.2011.5752094","DOIUrl":"https://doi.org/10.1109/MECBME.2011.5752094","url":null,"abstract":"In this paper, we experimentally investigated the navigation system of the nonpathogenic strain of E. coli (AW405) and developed a simulator for the locomotion performance of these swimming nanorobots. The swimming behavior of these cells is sensitive to the chemical gradients in their medium. Tissue and disease cells might produce chemical signals in their surroundings. These chemicals have the potential to affect the locomotion behavior of the bacterial cells. Therefore, bacterial cells can be considered as self-navigator nanorobots that are able to discriminate between disease cells such as cancer. Our current experimental and theoretical work is considered as a platform to this novel idea of early detection of problematic diseases.","PeriodicalId":348448,"journal":{"name":"2011 1st Middle East Conference on Biomedical Engineering","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128526414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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