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2011 1st Middle East Conference on Biomedical Engineering最新文献

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Assessing lung volumetric variation to detect and stage COPD 评估肺容量变化以检测和分期COPD
Pub Date : 2011-04-19 DOI: 10.1109/MECBME.2011.5752128
M. Hosseini, H. Soltanian-Zadeh, S. Akhlaghpoor
Chronic obstructive pulmonary disease (COPD) is a devastating disease. In this paper, we propose a novel method for scoring of air trapping in the lungs for detection and evaluation of COPD. The proposed method finds volumetric changes of the lungs from inspiration to expiration. To this end, trachea CT images at full inspiration and expiration are compared. For this comparison, the lungs parenchyma in the inspiration and expiration images are found and changes in the surface and volume of the lungs between inspiration and expiration are used to define quantitative measures (features). Using these features, the subjects are classified into two groups of normal class and COPD patients using a Bayesian classifier. In addition, t-tests are applied to evaluate discrimination powers of the features for this classification. The main advantage of the proposed method is its ability to estimate air trapping in the lungs from CT images without human intervention. The proposed method may assists radiologists in the detection of COPD as a computer aided diagnosis (CAD) system. It may also assist them with the scoring of the disease (severity of air trapping in the lungs).
慢性阻塞性肺疾病(COPD)是一种毁灭性疾病。在本文中,我们提出了一种新的方法来评估肺部的空气捕获,以检测和评估COPD。所提出的方法发现肺部从吸气到呼气的体积变化。为此,比较气管完全吸气和呼气时的CT图像。为了进行比较,在吸气和呼气图像中找到肺实质,并使用吸气和呼气之间肺表面和体积的变化来定义定量测量(特征)。利用这些特征,使用贝叶斯分类器将受试者分为正常类和COPD患者两组。此外,还应用t检验来评估该分类的特征的辨别能力。该方法的主要优点是能够在没有人为干预的情况下从CT图像中估计肺部的空气捕获。该方法可以作为计算机辅助诊断(CAD)系统帮助放射科医生检测COPD。它还可以帮助他们对疾病进行评分(肺部空气滞留的严重程度)。
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引用次数: 5
Default brain connectivity network in mild traumatic brain injury — preliminary MEG results 轻度创伤性脑损伤的默认脑连接网络-初步脑磁图结果
Pub Date : 2011-04-19 DOI: 10.1109/MECBME.2011.5752149
G. Zouridakis, Udit Patidar, L. Pollonini, Ning Situ, Roozbeh Rezaie, E. Castillo, H. Levin, A. Papanicolaou
In this study, we analyzed brain connectivity profiles from mild traumatic brain injury (mTBI) patients and normal controls. We computed Granger causality measures from magnetoencepha-lographic (MEG) activity obtained at the resting state, in an attempt to understand how the default network is affected by mTBI. Our results show that all subjects exhibit a dense network of peripheral local connections. However, normal controls show an additional network of long-range connections that is drastically reduced mTBI patients. These findings suggest that analysis of functional connectivity patterns may provide a valuable method for early detection of mTBI.
在这项研究中,我们分析了轻度创伤性脑损伤(mTBI)患者和正常对照者的脑连接概况。我们从静息状态下获得的脑磁图(MEG)活动中计算格兰杰因果关系,试图了解默认网络如何受到mTBI的影响。我们的研究结果表明,所有受试者都表现出密集的外围局部连接网络。然而,正常对照显示出额外的远程连接网络,这大大减少了mTBI患者。这些发现表明,分析功能连接模式可能为mTBI的早期检测提供有价值的方法。
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引用次数: 6
FES controller design based on threshold control theory for single joint movement 基于阈值控制理论的单关节运动FES控制器设计
Pub Date : 2011-04-19 DOI: 10.1166/jmihi.2011.1031
Lan Li, K. Zhu, U. Acharya, C. M. Lim
The threshold control theory is applied to build a physiology-based FES controller. The proposed control strategy is tested in simulation study with an integrated musculoskeletal model. The results suggest that the controller based on the threshold control theory alone can realize the task with small feedback delays. However, it is not capable to produce the movement fast enough to match the desired trajectory. Thus two extensions to improve the performance are proposed. Firstly, the feedback on actual movement velocity is replaced by the differences between the actual and desired velocities. Secondly, the feedback of joint angular acceleration is introduced to calculate the dynamic threshold. Simulation results suggest that such extensions can 1) improve the movement speed; 2) reduce the response time; and 3) reduce influence of external perturbation and feedback delays.
应用阈值控制理论构建了基于生理的FES控制器。该控制策略在一个肌肉-骨骼综合模型的仿真研究中得到了验证。结果表明,仅基于阈值控制理论的控制器就可以实现反馈延迟较小的任务。然而,它不能产生足够快的运动来匹配期望的轨迹。因此,提出了两种改进性能的扩展。首先,将实际运动速度的反馈替换为实际速度与期望速度的差值。其次,引入关节角加速度反馈来计算动态阈值;仿真结果表明,这样的扩展可以1)提高运动速度;2)减少响应时间;3)减少外部扰动和反馈延迟的影响。
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引用次数: 1
Psycho-physiological parameters to evaluate the mental demand during driving 用心理生理参数评价驾驶过程中的心理需求
Pub Date : 2011-04-19 DOI: 10.1109/MECBME.2011.5752117
S. Yoon, Jung-Yong Kim
The aim of this study was to develop parameters that could evaluate the driver's psycho-physiological response to road design during highway driving. A hypothesis was made such that people could drive safely if they had a proper level of ‘mental effort’ that could cover the ‘mental demand’ required by driving environment. This matching value of demand and effort was named as a ‘demand-effort matching profile (DEMP)’ in this study. In order to find psycho-physiological parameters satisfying DEMP in various road conditions, the mental ‘demand’ of the road environment was categorized into three: high, moderate, low demand. Seventy subjects participated in the experiment to measure the mental ‘effort’ during driving the vehicle equipped with measuring devices. 48 psycho-physiological parameters were examined in this study, and the parameters with consistent DEMP were summarized in this study. Those parameters could be used for further investigation of the relationship between drivers and road design.
本研究的目的是开发参数,以评估驾驶员在高速公路驾驶过程中对道路设计的心理生理反应。一个假设是,如果人们有适当的“精神努力”水平,可以覆盖驾驶环境所需的“精神需求”,那么人们就可以安全驾驶。本研究将需求与努力的匹配值命名为“需求-努力匹配曲线(DEMP)”。为了找到在各种道路条件下满足DEMP的心理生理参数,将道路环境的心理“需求”分为高、中、低三个层次。70名受试者参加了这项实验,以测量驾驶配备测量装置的车辆时的精神“努力”。本研究共检测了48个心理生理参数,总结了符合DEMP的参数。这些参数可用于进一步研究驾驶员与道路设计之间的关系。
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引用次数: 0
Breast sonogram and mammogram enhancement using hybrid and repetitive smoothing-sharpening technique 使用混合和重复平滑锐化技术的乳房超声和乳房x线照片增强
Pub Date : 2011-04-19 DOI: 10.1109/MECBME.2011.5752160
S. Al-Kindi, G. Al-Kindi
A novel hybrid and repetitive smoothing-sharpening (HRSST) technique is proposed and its impact is assessed to beneficially enhance sonogram and mammogram images. The technique aims to gain and combine the advantages of both the sharpening process that aims to highlight sudden changes in the image intensity, with the advantages of iterative image smoothing, which is usually applied to remove random noise from digital images. Nevertheless the developed technique also eliminates the drawbacks of each of the two sharpening and smoothing techniques resulting from their individual application in image processing field. The proposed technique is tested on both breast ultra-sound (BUS) as well as breast X-ray mammograms. Results show that the proposed methodology has high potential to advantageously enhance the image contrast hence giving extra aid to radiologists to detect and classify sonograms and mammograms
提出了一种新的混合和重复平滑锐化(HRSST)技术,并评估了其对超声和乳房x光图像的有益增强效果。该技术旨在获得并结合锐化过程的优点,锐化过程旨在突出图像强度的突然变化,迭代图像平滑通常用于去除数字图像中的随机噪声。然而,所开发的技术也消除了两种锐化和平滑技术各自在图像处理领域的应用所造成的缺点。所提出的技术在乳房超声波(BUS)和乳房x射线乳房x光检查中进行了测试。结果表明,所提出的方法具有很高的潜力,有利于提高图像对比度,从而为放射科医生检测和分类超声和乳房x光片提供额外的帮助
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引用次数: 13
Monitoring patients' signs wirelessly 无线监测患者体征
Pub Date : 2011-04-19 DOI: 10.1109/MECBME.2011.5752121
A. Sagahyroon, F. Aloul, A. Al-Ali, M. S. Bahrololoum, F. Makhsoos, N. Hussein
Recent developments in off-the-shelf wireless embedded computing boards and the increasing need for efficient health monitoring systems, fueled by the increasing number of patients, has prompted R&D professionals to explore better health monitoring systems that are both mobile and cheap. This work investigates the feasibility of using the ZigBee embedded technology in health-related monitoring applications. Selected vital signs of patients are acquired using sensor nodes and readings are transmitted wirelessly using devices that utilize the ZigBee communications protocols. A prototype system has been developed and tested with encouraging results.
在现成的无线嵌入式计算板的最新发展和对高效健康监测系统的日益增长的需求,以及越来越多的患者的推动下,促使研发专业人员探索更好的移动和廉价的健康监测系统。本研究探讨了在健康监测应用中使用ZigBee嵌入式技术的可行性。使用传感器节点获取选定的患者生命体征,并使用利用ZigBee通信协议的设备无线传输读数。一个原型系统已经开发和测试,并取得了令人鼓舞的结果。
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引用次数: 14
Discriminating affective states in music induction environment using forehead bioelectric signals 利用前额生物电信号识别音乐诱导环境中的情感状态
Pub Date : 2011-04-19 DOI: 10.1109/MECBME.2011.5752136
Roya Hashemi Rad, M. Firoozabadi, I. Rezazadeh
Forehead bioelectric signals are reliable and rich communication channels for emotion recognition in cognitive studies. In this paper, we explored the effects of two different music induction environments on multichannel forehead bioelectric signals. Pleasant and irritating emotions were induced by playing two different types of music that had different specifications according to the Arousal-Valence emotional space. Simultaneously, the bioelectric signals from three physical channels were recorded and filtered to extract entropy of Alpha and EMG sub-bands over 256msec time slots. By analyzing results using the Wilcoxon test, it was shown that Alpha and EMG sub-bands are significant data channels for emotion discrimination.
前额生物电信号是认知研究中可靠而丰富的情绪识别交流渠道。本文探讨了两种不同的音乐感应环境对前额多通道生物电信号的影响。根据唤醒效价情绪空间,演奏两种不同类型的音乐可诱发愉快和恼怒的情绪。同时,记录三个物理通道的生物电信号并对其进行滤波,提取256msec时间段内α和肌电子带的熵。通过Wilcoxon检验分析结果,发现Alpha和EMG子带是情绪识别的重要数据通道。
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引用次数: 5
Study the effects of using CW and pulsed diode lasers on burns healing 研究连续波和脉冲二极管激光对烧伤愈合的影响
Pub Date : 2011-04-19 DOI: 10.1109/MECBME.2011.5752085
M. S. Dawood, Rawaa T. Shukry, A. Al-Salihi
This paper focused on studying the effect of diode laser on the burn healing. The study is based on using 32 mature, male albino mice divided into four groups, all groups were burned using an electrical soldering unit on the back of each mouse for five seconds to create a 3rd degree burn of 1 cm in length. Two groups were treated with diode laser. The first group (S1) is treated with 785nm, 3.5mW CW diode laser for 3 minutes to get energy density = 3J/cm2. The second group (S2) is illuminated by using CW diode laser of 637nm, 2mW for 5 minutes with the same energy density, while the pulsed group (group S3) is treated by pulsed diode laser (637nm) of pulse repetition frequency (p.r.f) 1 KHz and duty cycles, 50%. One group of these animals was not irradiated by laser energy. It is used as a control group. The animals were irradiated three times per week. The first laser irradiation was given immediately after burn creation followed by the two other exposures at the next 2nd and 3rd day after burning. The histological assessment was started at day 4 after the burn and carried on for 25 days; once per week. The results showed that for a CW laser groups; the re-epithelialization appear one week earlier in laser group S2 (CW-637nm wavelength, 2mW) at day 18, while in the control group appear only at day 25 after burn. The hair follicles in this group seem to appear more quickly than the control group. The pulsed laser showed also better results comparing to the result of CW diode laser.
本文主要研究了二极管激光对烧伤愈合的影响。这项研究是基于32只成熟的雄性白化小鼠,分为四组,每组都在每只小鼠的背部使用电焊装置烧伤5秒钟,造成1厘米长的三度烧伤。两组均采用二极管激光治疗。第一组(S1)用785nm、3.5mW连续二极管激光照射3分钟,得到能量密度= 3J/cm2。第二组(S2)用637nm、2mW的连续二极管激光器照射5分钟,能量密度相同,而脉冲组(S3)用脉冲重复频率(p.r.f)为1 KHz、占空比为50%的脉冲二极管激光器(637nm)照射。其中一组动物没有受到激光能量的照射。它被用作一个对照组。这些动物每周接受三次辐射。第一次激光照射在烧伤后立即进行,然后在烧伤后的第2天和第3天进行两次其他照射。组织学评估于烧伤后第4天开始,持续25天;每周一次。结果表明:对于连续波激光组;激光S2组(CW-637nm波长,2mW)在烧伤后第18天出现1周的再上皮化,而对照组仅在烧伤后第25天出现。这一组的毛囊似乎比对照组长得更快。与连续波二极管激光器相比,脉冲激光器也显示出更好的效果。
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引用次数: 0
Casecube: An internet-based, intercultural, interprofessional master's curriculum Biomedical Engineering Casecube:一个基于互联网、跨文化、跨专业的生物医学工程硕士课程
Pub Date : 2011-04-19 DOI: 10.1109/MECBME.2011.5752069
W. Molenaar, G. J. Verkerke
An internet-based, intercultural and interprofessional 2 years Master's curriculum Biomedical Engineering was developed by a joint effort of 3 Asian and 3 European Universities. The curriculum consists of a mixture of face-to-face and e-learning courses (‘blended learning’) and was developed and taught by teachers from all participating institutes. The internet based courses are supported by chat sessions and annual summer schools where all students and teachers meet. To test the curriculum 13 students with different cultural (Asian — European) and educational (health care — engineering) background enrolled, of which 8 graduated so far. External and internal evaluations were conducted and showed that the developed curriculum can be implemented with some adaptations in course contents and in the management and organization.
生物医学工程是由3所亚洲和3所欧洲大学共同开发的基于互联网的跨文化和跨专业两年制硕士课程。该课程由面对面和电子学习课程(“混合式学习”)组成,由所有参与机构的教师开发和教授。网络课程由聊天会议和一年一度的暑期学校提供支持,所有学生和老师都在那里见面。为了测试课程,13名不同文化背景(亚洲-欧洲)和教育背景(卫生保健-工程)的学生入学,其中8人毕业。进行了外部和内部的评估,并表明开发的课程可以在课程内容和管理组织方面进行一些调整。
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引用次数: 0
Device for indexing peripheral neuropathy 周围神经病变索引装置
Pub Date : 2011-04-19 DOI: 10.1109/MECBME.2011.5752107
M. Jacobson, Klaithem Ali Ameri, A. Al Braiki
A prototype device for improved assessment of clinical diabetic neuropathy was designed, developed, and pilot tested by students of the Design of Medical Devices II course, which is part of the biomedical engineering program of the Higher Colleges of Technology in the United Arab Emirates. Specifically, students identified a specific clinical problem faced by healthcare staff in the screening of diabetes mellitus complications and researched possible solutions in consideration of patient care, ease of use, and assessment effectiveness. In response, students designed and pilot tested PAD, Peripheral nerve Assessment Device, which is a prototype that meets the design criteria of the healthcare staff through digital indexing of sensory nerve perception.
一种用于改进临床糖尿病神经病变评估的原型设备由医疗设备设计II课程的学生设计、开发和试点测试,该课程是阿拉伯联合酋长国高等技术学院生物医学工程项目的一部分。具体来说,学生们发现了医护人员在筛查糖尿病并发症时面临的一个具体临床问题,并考虑到病人护理、使用方便和评估效果,研究了可能的解决方案。为此,学生设计并试点了PAD (Peripheral nerve Assessment Device),该设备通过对感觉神经知觉进行数字化标引,符合医护人员的设计标准。
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引用次数: 1
期刊
2011 1st Middle East Conference on Biomedical Engineering
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