Pub Date : 1900-01-01DOI: 10.56936/18290825-2022.16.3-70
M. A. Jauhani, A. Setyawardani, D.C. Dewi, E.N. Akhtar, L.H. Putri
Introduction: Indonesia is one of the developing countries that have various cultures, ethnicities, and mysticism. Those things influence their society, especially the people in the low middle class and uneducated well. Many people still believe that a disease can occur due to mystical things, so they believe that a dukun can treat it, even if the process is illogical. This phenomenon nowadays still exists in society. Dukun usually has his way to cure or solve someone’s diseases, even though his methods to cure someone’s diseases usually do not have evidence-based and the diseases need to see professionals. It shows in this case. Dukun in this case used ice blocks as his method to cure someone’s disease. This “ice blocks therapy” may trigger hypothermia conditions in someone and also may cause death, especially in a person with chronic disease. The range temperature in the Jember Regency between 21-31oC which makes hypothermia rarely found here. The case will present in this paper. In this case, we present an interesting case about the use of ice blocks, called “ice blocks therapy” and then considered as a therapy method and an unexpected death. Conclusions: Review of patient history, postmortem findings, forensic pathology, and socio-cultural aspects are some of the keys to solving the problem. In this case, hypothermia through ice block therapy plays a role in decreasing organ function which results in death
{"title":"Autopsy findings in unexpected death associated with “ice block therapy” trigger hypothermia: A case report","authors":"M. A. Jauhani, A. Setyawardani, D.C. Dewi, E.N. Akhtar, L.H. Putri","doi":"10.56936/18290825-2022.16.3-70","DOIUrl":"https://doi.org/10.56936/18290825-2022.16.3-70","url":null,"abstract":"Introduction: Indonesia is one of the developing countries that have various cultures, ethnicities, and mysticism. Those things influence their society, especially the people in the low middle class and uneducated well. Many people still believe that a disease can occur due to mystical things, so they believe that a dukun can treat it, even if the process is illogical. This phenomenon nowadays still exists in society. Dukun usually has his way to cure or solve someone’s diseases, even though his methods to cure someone’s diseases usually do not have evidence-based and the diseases need to see professionals. It shows in this case. Dukun in this case used ice blocks as his method to cure someone’s disease. This “ice blocks therapy” may trigger hypothermia conditions in someone and also may cause death, especially in a person with chronic disease. The range temperature in the Jember Regency between 21-31oC which makes hypothermia rarely found here. The case will present in this paper. \u0000In this case, we present an interesting case about the use of ice blocks, called “ice blocks therapy” and then considered as a therapy method and an unexpected death. \u0000Conclusions: Review of patient history, postmortem findings, forensic pathology, and socio-cultural aspects are some of the keys to solving the problem. In this case, hypothermia through ice block therapy plays a role in decreasing organ function which results in death","PeriodicalId":353660,"journal":{"name":"THE NEW ARMENIAN MEDICAL JOURNAL","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131000427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.56936/18290825-2022.16.4-41
S. Avagyan, A. Zilfyan, A. Muradyan, Hovhanes Gazaryan
Polyamines (putrescine, spermidine and spermine) as well as γ- and α-synucleins are currently the subject of a special comprehensive study due to their direct influence on the formation of neoplastic processes. This review article presents informative data on the role of aliphatic polyamines (putrescine, spermidine, spermine) in the induction of a number of oncological diseases with their localization in the digestive and urinary systems. Aspects related to the synthesis and aggregation of γ-synucleins into malignantly reborn cells have been discussed. The article provides information on the possible prevention of further growth of malignant cells, by inhibiting enzymatic processes responsible for the polyamine synthesis. In case of prolonged persistence of Helicobacter Pylori in the stomach, an enhanced synthesis of polyamines and cumulation in situ of oligo- and aggregated gamma synucleins occurs in mucous membrane cells. It is possible that all of the abovementioned factors in total directly and/or indirectly have a stimulating effect on the processes of the malignancy of gastric mucosal cells. The subject of special discussion was the latest literature data, according to which, under the conditions of Helicobacter Pylori persistence in the digestive tract organs, in the gastric mucosal cells an enhanced synthesis of putrescine occurs, high concentrations of which can have a co-carcinogenic effect on normally functioning target cells. From a qualitatively new point of view, the fact of cumulation in malignantly reborn cells of an aggregated gamma synuclein, which was found during Helicobacter Pylori infection, should be considered.
{"title":"Potential significance of aliphatic polyamines, α-synucleins and Helicobacter Pylori in diagnostics and prognosis of some malignant tumors.","authors":"S. Avagyan, A. Zilfyan, A. Muradyan, Hovhanes Gazaryan","doi":"10.56936/18290825-2022.16.4-41","DOIUrl":"https://doi.org/10.56936/18290825-2022.16.4-41","url":null,"abstract":"Polyamines (putrescine, spermidine and spermine) as well as γ- and α-synucleins are currently the subject of a special comprehensive study due to their direct influence on the formation of neoplastic processes. \u0000This review article presents informative data on the role of aliphatic polyamines (putrescine, spermidine, spermine) in the induction of a number of oncological diseases with their localization in the digestive and urinary systems. Aspects related to the synthesis and aggregation of γ-synucleins into malignantly reborn cells have been discussed. The article provides information on the possible prevention of further growth of malignant cells, by inhibiting enzymatic processes responsible for the polyamine synthesis.\u0000In case of prolonged persistence of Helicobacter Pylori in the stomach, an enhanced synthesis of polyamines and cumulation in situ of oligo- and aggregated gamma synucleins occurs in mucous membrane cells. It is possible that all of the abovementioned factors in total directly and/or indirectly have a stimulating effect on the processes of the malignancy of gastric mucosal cells.\u0000The subject of special discussion was the latest literature data, according to which, under the conditions of Helicobacter Pylori persistence in the digestive tract organs, in the gastric mucosal cells an enhanced synthesis of putrescine occurs, high concentrations of which can have a co-carcinogenic effect on normally functioning target cells. From a qualitatively new point of view, the fact of cumulation in malignantly reborn cells of an aggregated gamma synuclein, which was found during Helicobacter Pylori infection, should be considered.","PeriodicalId":353660,"journal":{"name":"THE NEW ARMENIAN MEDICAL JOURNAL","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125306088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.56936/18290825-2022.16.4-36
N. Stepanyan, S. Badalyan, V.A. Aleksanyan, R.A. Nazinyan, A.V. Zaqaryan, M.V. Kalashyan, R. Fanarjyan
Intervertebral disc herniation, which is an inevitable and aging process due to intervertebral discs unique anatomical and physiologic characteristics and spine biomechanics, can lead to compression of one or more nerve roots, producing radiculopathy. There are two treatment options non-surgical and surgical or the combination of both depending on individual clinical findings for this issue. Surgical management includes several options with different success and complications rate. The options also have different implementation rate. The aim of current study is to show the efficacy and safety of microdiscectomy as a surgical treatment option in our clinical practice. We enrolled 91 patients from 2019 to 2021, who were operated using microdiscectomy technique, discharged within few days and were prescribed to use semi-hard lumbar brace for a month and were followed up until 2022 November. No any patient was considered as a surgical management candidate simply for low back pain. Immediate and complete or nearly-complete pain relief, sensory deficit and motor weakness improvement were the predictors of surgical management success and were achieved in all patients. There were no cases of intraoperative complications and failed back surgery. One patient (1.1%, 1/91) developed cerebrospinal fluid leakage from the wound on postoperative day 7, which resolved with additional dermal sutures. Recurrence rate of disc herniation was 1.1% (1/91). This patient was successfully reoperated without significant quality of life affection. The implementation of microdiscectomy technique in our clinical practice was successful, and from medical point of view highly effective and safe surgical management option for treatment of disc herniation with radiculopathy in cases where non-surgical management options failed to resolve the issue or there were indications for urgent surgical management. We hope that this technique eventually will become a gold standard for surgical treatment of disc herniation with radiculopathy in Armenia.
{"title":"Microdiscectomy: An Observational Study. The New Armenian Medical Journal","authors":"N. Stepanyan, S. Badalyan, V.A. Aleksanyan, R.A. Nazinyan, A.V. Zaqaryan, M.V. Kalashyan, R. Fanarjyan","doi":"10.56936/18290825-2022.16.4-36","DOIUrl":"https://doi.org/10.56936/18290825-2022.16.4-36","url":null,"abstract":"Intervertebral disc herniation, which is an inevitable and aging process due to intervertebral discs unique anatomical and physiologic characteristics and spine biomechanics, can lead to compression of one or more nerve roots, producing radiculopathy. There are two treatment options non-surgical and surgical or the combination of both depending on individual clinical findings for this issue. Surgical management includes several options with different success and complications rate. The options also have different implementation rate. The aim of current study is to show the efficacy and safety of microdiscectomy as a surgical treatment option in our clinical practice. We enrolled 91 patients from 2019 to 2021, who were operated using microdiscectomy technique, discharged within few days and were prescribed to use semi-hard lumbar brace for a month and were followed up until 2022 November. No any patient was considered as a surgical management candidate simply for low back pain. Immediate and complete or nearly-complete pain relief, sensory deficit and motor weakness improvement were the predictors of surgical management success and were achieved in all patients. There were no cases of intraoperative complications and failed back surgery. One patient (1.1%, 1/91) developed cerebrospinal fluid leakage from the wound on postoperative day 7, which resolved with additional dermal sutures. Recurrence rate of disc herniation was 1.1% (1/91). This patient was successfully reoperated without significant quality of life affection.\u0000The implementation of microdiscectomy technique in our clinical practice was successful, and from medical point of view highly effective and safe surgical management option for treatment of disc herniation with radiculopathy in cases where non-surgical management options failed to resolve the issue or there were indications for urgent surgical management. We hope that this technique eventually will become a gold standard for surgical treatment of disc herniation with radiculopathy in Armenia.","PeriodicalId":353660,"journal":{"name":"THE NEW ARMENIAN MEDICAL JOURNAL","volume":"132 9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124250823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.56936/18290825-2022.16.4-23
A.A. Kesoyan, N.L. Arakelyan, D.A. Aloyan, A. Karapetyan, H. Manvelyan
It’s well known that smoking cigarettes is causally linked to a number of serious mortal diseases. These include laryngeal, lung, bladder, and digestive tract cancers, chronic obstructive pulmonary disease and a number of cardiovascular diseases, such as aortic aneurysm, stroke, and ischemic heart disease. In 2014, U.S. Surgeon General Report states that smoking is causally associated with inflammation and impaired immune function, and that regular smokers are at higher risk of developing pneumonia, tuberculosis, and other airway infections. So the best way to avoid harm from smoking is to never start, and for smokers to quit. However, evidence from epidemiological studies suggests a relationship between cigarette smoking and low risk of Parkinson’s disease. As a major component of tobacco smoke, nicotine has been proposed to be a substance for preventing against Parkinson’s disease risk, with a key role in regulating striatal activity and behaviors mediated through the dopaminergic system. Another data suggests quick deterioration and disease exacerbation after smoking cessation. Animal studies also showed that nicotine could modulate dopamine transmission and reduce levodopa-induced dyskinesias. Smoking cessation, proposed because of the health issues as certainly reducing the risk of cardiovascular events and cancer, must be definitely accepted as major health paramount procedure, but in the case of Parkinson’s disease nicotine-substitute supplements must be provided. As a small amount of nicotine can saturate a substantial portion of nicotine receptors in the brain, nicotine from other sources, such as less harmful smoking advanced devices as well as diet, could be a promising therapeutic substance for motility support and protection against Parkinson’s disease.
{"title":"Cigarette Smoking, nicotine and Parkinson’s disease: Controversies in clinical trials data and medical practice.","authors":"A.A. Kesoyan, N.L. Arakelyan, D.A. Aloyan, A. Karapetyan, H. Manvelyan","doi":"10.56936/18290825-2022.16.4-23","DOIUrl":"https://doi.org/10.56936/18290825-2022.16.4-23","url":null,"abstract":"It’s well known that smoking cigarettes is causally linked to a number of serious mortal diseases. These include laryngeal, lung, bladder, and digestive tract cancers, chronic obstructive pulmonary disease and a number of cardiovascular diseases, such as aortic aneurysm, stroke, and ischemic heart disease.\u0000In 2014, U.S. Surgeon General Report states that smoking is causally associated with inflammation and impaired immune function, and that regular smokers are at higher risk of developing pneumonia, tuberculosis, and other airway infections. So the best way to avoid harm from smoking is to never start, and for smokers to quit. \u0000However, evidence from epidemiological studies suggests a relationship between cigarette smoking and low risk of Parkinson’s disease. As a major component of tobacco smoke, nicotine has been proposed to be a substance for preventing against Parkinson’s disease risk, with a key role in regulating striatal activity and behaviors mediated through the dopaminergic system. Another data suggests quick deterioration and disease exacerbation after smoking cessation. Animal studies also showed that nicotine could modulate dopamine transmission and reduce levodopa-induced dyskinesias.\u0000Smoking cessation, proposed because of the health issues as certainly reducing the risk of cardiovascular events and cancer, must be definitely accepted as major health paramount procedure, but in the case of Parkinson’s disease nicotine-substitute supplements must be provided. As a small amount of nicotine can saturate a substantial portion of nicotine receptors in the brain, nicotine from other sources, such as less harmful smoking advanced devices as well as diet, could be a promising therapeutic substance for motility support and protection against Parkinson’s disease.","PeriodicalId":353660,"journal":{"name":"THE NEW ARMENIAN MEDICAL JOURNAL","volume":"34 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122149120","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.56936/18290825-2022.16.1-4
A. Zilfyan, S. Avagyan, A. Muradyan, E.S. Barsegyan
This article presents our views on main scientific and methodological approaches regarding the advantages of conducting mass vaccination of healthy individuals and COVID-19 convalescents. First of all, the focus is on issues regarding the antigenic potencies of SARS-CoV-2, based on which vaccines have been created over the past three years that have successfully passed preclinical and clinical testing, as well as licensing. The subjects of specal discussion were aspects related to the short-term effect of the main vaccines, as a result of which revaccination is recommended. It is assumed that more than one antigenic determinant is expressed on the surface of SARS-CoV-2. In the conclusion paragraph, we have presented our own concept on most topical situational issues among the population of many countries in the process of vaccination against COVID-19. Is it worth getting vaccinated at all if complications can arise that lead to disability and death even in practically healthy individuals, not to mention the elderly contingent with chronic diseases? In making a positive decision, the question arises in terms of choosing a vaccine, since vaccines are used in different countries, in the production of which different scientific, methodological and technological approaches are used. If there is a need for re-vaccination within a short period after the first vaccination? As a rule, it is recommended to re-vaccinate in 14-30 days after the first vaccination. In this regard, there are concerns about the low efficacy (weak selective immunogenic activity) of vaccines. How expedient, if not contraindicated, is to “fully” vaccinate patients in the recovery period, as well as over the next one to two months, if they have high levels of SARS-CoV-2 antibodies? In case of re-vaccination, it is necessary to find out whether it is possible to get the second vaccination using a commercial vaccine of another manufacturer, especially since many developing countries do not currently have such a vaccine that has been introduced during the first vaccination. How competent is it to vaccinate a wide range of healthy individuals against COVID-19 and influenza - for the same time or with the shortest time interval?
{"title":"Recommended tactics for mass vaccination of healthy individuals and COVID-19 convalescents","authors":"A. Zilfyan, S. Avagyan, A. Muradyan, E.S. Barsegyan","doi":"10.56936/18290825-2022.16.1-4","DOIUrl":"https://doi.org/10.56936/18290825-2022.16.1-4","url":null,"abstract":"This article presents our views on main scientific and methodological approaches regarding the advantages of conducting mass vaccination of healthy individuals and COVID-19 convalescents.\u0000First of all, the focus is on issues regarding the antigenic potencies of SARS-CoV-2, based on which vaccines have been created over the past three years that have successfully passed preclinical and clinical testing, as well as licensing. The subjects of specal discussion were aspects related to the short-term effect of the main vaccines, as a result of which revaccination is recommended. It is assumed that more than one antigenic determinant is expressed on the surface of SARS-CoV-2.\u0000In the conclusion paragraph, we have presented our own concept on most topical situational issues among the population of many countries in the process of vaccination against COVID-19.\u0000Is it worth getting vaccinated at all if complications can arise that lead to disability and death even in practically healthy individuals, not to mention the elderly contingent with chronic diseases?\u0000In making a positive decision, the question arises in terms of choosing a vaccine, since vaccines are used in different countries, in the production of which different scientific, methodological and technological approaches are used.\u0000If there is a need for re-vaccination within a short period after the first vaccination?\u0000As a rule, it is recommended to re-vaccinate in 14-30 days after the first vaccination. In this regard, there are concerns about the low efficacy (weak selective immunogenic activity) of vaccines.\u0000How expedient, if not contraindicated, is to “fully” vaccinate patients in the recovery period, as well as over the next one to two months, if they have high levels of SARS-CoV-2 antibodies?\u0000In case of re-vaccination, it is necessary to find out whether it is possible to get the second vaccination using a commercial vaccine of another manufacturer, especially since many developing countries do not currently have such a vaccine that has been introduced during the first vaccination.\u0000How competent is it to vaccinate a wide range of healthy individuals against COVID-19 and influenza - for the same time or with the shortest time interval?","PeriodicalId":353660,"journal":{"name":"THE NEW ARMENIAN MEDICAL JOURNAL","volume":"85 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124919369","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.56936/18290825-2022.16.1-109
T. Purwanti, M.S. Erfan Kusuma, A. Yudianto
Child abuse has negative impact for children including emotional performance, mental dysfunction, and decrease intelligence. According to the 2014 Surveillance Report of Traumatic Brain Injury, in the United States, there are approximately 2.87 million head injury patients. Head injury, or so-called head trauma, is a blunt force/sharp force on the head or face that results in temporary cerebral dysfunction. It is one of the leading causes of death and disability in the productive age group, primarily traffic accidents. A boy went to the emergency room at Bhayangkara Kediri Hospital. There was swelling on the left head, expanding on the forehead and bruising on the left ear. Also found signs of sodomy marks in the form of abrasions around the anus. There are also bruises on the back and neck of the end. For a definitive diagnosis, the results of the CT scan were that the patient obtained extensive cerebral contusion and caused the deviation of the midline structure to the right as far as ± 0.9 cm with subgaleal hematoma and the dilation of cerebral blood vessels. In cases of head injury due to blunt trauma, blood infiltration will be found in the layers of the scalp and muscles in the direction of the trauma. The presence of blood infiltration is an intravital sign of evidence of extravasation of blood cells in the tissue. Another finding may be a skull base fracture in the posterior fossa caused by a direct blow to the occipital region. At the base of the skull, a fracture in the posterior fossa can cause symptoms such as bleeding from the nose, mouth, and ears, damage to the cranial nerves and cause raccoon eyes. In head injuries caused by blunt trauma can also cause subarachnoid hemorrhage and subdural hemorrhage due to rupture of the superior cerebral vein and “bridging vein” due to pressure/trauma it can cause death, to distinguish subarachnoid hemorrhage from subdural hemorrhage needs to be done sprinkling with water.
{"title":"Head injury case with blunt force traumatic: Case report","authors":"T. Purwanti, M.S. Erfan Kusuma, A. Yudianto","doi":"10.56936/18290825-2022.16.1-109","DOIUrl":"https://doi.org/10.56936/18290825-2022.16.1-109","url":null,"abstract":"Child abuse has negative impact for children including emotional performance, mental dysfunction, and decrease intelligence.\u0000According to the 2014 Surveillance Report of Traumatic Brain Injury, in the United States, there are approximately 2.87 million head injury patients. Head injury, or so-called head trauma, is a blunt force/sharp force on the head or face that results in temporary cerebral dysfunction. It is one of the leading causes of death and disability in the productive age group, primarily traffic accidents.\u0000A boy went to the emergency room at Bhayangkara Kediri Hospital. There was swelling on the left head, expanding on the forehead and bruising on the left ear. Also found signs of sodomy marks in the form of abrasions around the anus. There are also bruises on the back and neck of the end.\u0000For a definitive diagnosis, the results of the CT scan were that the patient obtained extensive cerebral contusion and caused the deviation of the midline structure to the right as far as ± 0.9 cm with subgaleal hematoma and the dilation of cerebral blood vessels.\u0000In cases of head injury due to blunt trauma, blood infiltration will be found in the layers of the scalp and muscles in the direction of the trauma. The presence of blood infiltration is an intravital sign of evidence of extravasation of blood cells in the tissue. Another finding may be a skull base fracture in the posterior fossa caused by a direct blow to the occipital region. At the base of the skull, a fracture in the posterior fossa can cause symptoms such as bleeding from the nose, mouth, and ears, damage to the cranial nerves and cause raccoon eyes. In head injuries caused by blunt trauma can also cause subarachnoid hemorrhage and subdural hemorrhage due to rupture of the superior cerebral vein and “bridging vein” due to pressure/trauma it can cause death, to distinguish subarachnoid hemorrhage from subdural hemorrhage needs to be done sprinkling with water.","PeriodicalId":353660,"journal":{"name":"THE NEW ARMENIAN MEDICAL JOURNAL","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125017210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.56936/18290825-2022.16.1-17
ArmeNiAN medicAl JourNAl, hakoByan h.h, Hovhannes H. Hakobyan
Caregiving a child with special needs requires additional physical, psychological and financial resources. Current knowledge confirms that caregivers of children with functional limitations (i.e., cerebral palsy) are under greater risk of developing physical and psychological health problems. However, health characteristics of caregivers are not well investigated in low- and middle-income countries. Current observational study aimed to discover the anxiety and pain syndromes among caregivers of children with cerebral palsy residing in Armenia. Cross-sectional study was conducted in tertiary care center in 2015-2016. Demographic and health information was collected from eligible participants. Anxiety was measured by Norakidze’s modification of Taylor Manifest Anxiety Scale 60-items scale. Descriptive statistics was utilized for demographic data, chi square and regression analysis for exploratory analysis of anxiety and pain among caregivers. From 193 caregivers 188 (97.4%) were mothers with mean age of 37 (SD=10.6). Over two third of participants reported to have chronic pain syndromes. Moreover, 14% participants precepted pain every day. Pain syndromes mainly were associated with caregiving time. High anxiety levels according to Taylor Manifest Anxiety Scale 60-items scale were presented in 135 (69.9%) of caregivers. Correlations between anxiety and caregivers/children characteristics were investigated. This is the first publication about health characteristics of caregivers of children with cerebral palsy in Armenia. Current study design lacks to find causations, and has not control for confounders. However, study findings emphasize the necessity for further research of health problems of caregivers of children with cerebral palsy.
{"title":"Anxiety and chronic pain in caregivers of children with cerebral palsy in Armenia: descriptive study","authors":"ArmeNiAN medicAl JourNAl, hakoByan h.h, Hovhannes H. Hakobyan","doi":"10.56936/18290825-2022.16.1-17","DOIUrl":"https://doi.org/10.56936/18290825-2022.16.1-17","url":null,"abstract":"Caregiving a child with special needs requires additional physical, psychological and financial resources. Current knowledge confirms that caregivers of children with functional limitations (i.e., cerebral palsy) are under greater risk of developing physical and psychological health problems. However, health characteristics of caregivers are not well investigated in low- and middle-income countries. Current observational study aimed to discover the anxiety and pain syndromes among caregivers of children with cerebral palsy residing in Armenia.\u0000Cross-sectional study was conducted in tertiary care center in 2015-2016. Demographic and health information was collected from eligible participants. Anxiety was measured by Norakidze’s modification of Taylor Manifest Anxiety Scale 60-items scale. Descriptive statistics was utilized for demographic data, chi square and regression analysis for exploratory analysis of anxiety and pain among caregivers.\u0000From 193 caregivers 188 (97.4%) were mothers with mean age of 37 (SD=10.6). Over two third of participants reported to have chronic pain syndromes. Moreover, 14% participants precepted pain every day. Pain syndromes mainly were associated with caregiving time. High anxiety levels according to Taylor Manifest Anxiety Scale 60-items scale were presented in 135 (69.9%) of caregivers. Correlations between anxiety and caregivers/children characteristics were investigated.\u0000This is the first publication about health characteristics of caregivers of children with cerebral palsy in Armenia. Current study design lacks to find causations, and has not control for confounders. However, study findings emphasize the necessity for further research of health problems of caregivers of children with cerebral palsy.","PeriodicalId":353660,"journal":{"name":"THE NEW ARMENIAN MEDICAL JOURNAL","volume":"2013 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129879980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.56936/18290825-2022.16.4-96
N. Ghazaryan, A.H. Khachatryan, Miqayel Adamyan, T. Hovakimyan
Background: The number of cardiac implantable electronic device implantation procedures has increased dramatically in recent decades due to population aging and expansion of indications. At the same time, the number of cardiac implantable electronic device associated complications has increased too. Infection is a very important and heavy complication of cardiac implantable electronic device implantation, which significantly increases mortality and morbidity. This study aimed to estimate the risk of cardiac implantable electronic device infection in a group of patients who received an aggressive scheme of postoperative antibiotic therapy and compare this with the risk of infection in another group, where a mild antibiotic therapy scheme was used. Methods: A retrospective, observational study was performed. The study sample included 355 patients. Two antibiotic prophylaxis and wound follow-up protocols (mild and aggressive) were used. In this study the effectiveness of both methods to prevent a cardiac implantable electronic device related infection was compared. Results: The prevalence of infection was 3.5% in the group with mild scheme and 1.13% in the group with the aggressive scheme. The difference in two subgroups was not significant (p=0,149). According to this study severe renal failure, chronic obstructive pulmonary disease and thyroid dysfunction were found as significant predictors for having cardiac implantable electronic device infection. In participants who underwent a reimplantation and in those with postoperative hematoma the odds of having infection was higher, compared to patients with primary implantation and absence of hematoma. Age of participants with cardiac implantable electronic device infection was younger compared to patients without infection. Conclusion: According to this study there is no statistically significant difference on cardiac implantable electronic device infection between mild and aggressive antibiotic therapy schemes.
{"title":"Cardiac implantable electronic device infection: prevalence and risk factors (A single center experience)","authors":"N. Ghazaryan, A.H. Khachatryan, Miqayel Adamyan, T. Hovakimyan","doi":"10.56936/18290825-2022.16.4-96","DOIUrl":"https://doi.org/10.56936/18290825-2022.16.4-96","url":null,"abstract":"Background: The number of cardiac implantable electronic device implantation procedures has increased dramatically in recent decades due to population aging and expansion of indications. At the same time, the number of cardiac implantable electronic device associated complications has increased too. Infection is a very important and heavy complication of cardiac implantable electronic device implantation, which significantly increases mortality and morbidity.\u0000This study aimed to estimate the risk of cardiac implantable electronic device infection in a group of patients who received an aggressive scheme of postoperative antibiotic therapy and compare this with the risk of infection in another group, where a mild antibiotic therapy scheme was used. \u0000Methods: A retrospective, observational study was performed. The study sample included 355 patients. Two antibiotic prophylaxis and wound follow-up protocols (mild and aggressive) were used. In this study the effectiveness of both methods to prevent a cardiac implantable electronic device related infection was compared. \u0000Results: The prevalence of infection was 3.5% in the group with mild scheme and 1.13% in the group with the aggressive scheme. The difference in two subgroups was not significant (p=0,149). \u0000According to this study severe renal failure, chronic obstructive pulmonary disease and thyroid dysfunction were found as significant predictors for having cardiac implantable electronic device infection. In participants who underwent a reimplantation and in those with postoperative hematoma the odds of having infection was higher, compared to patients with primary implantation and absence of hematoma. Age of participants with cardiac implantable electronic device infection was younger compared to patients without infection. \u0000Conclusion: According to this study there is no statistically significant difference on cardiac implantable electronic device infection between mild and aggressive antibiotic therapy schemes.","PeriodicalId":353660,"journal":{"name":"THE NEW ARMENIAN MEDICAL JOURNAL","volume":"96 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125992817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.56936/18290825-2022.16.1-101
S. Panahi, G. Sabz, A. Jokartangkarami, S. Afroughi, F. Karimpour
It is widely accepted that any interventional treatment, such as surgery, requires a precise and predetermined treatment plan. Moreover, conventional images do not allow for the presentation of all canal dimensions, and patients concepts of beauty and their expectations are greater for the premaxilla region. Therefore, the use of three-dimensional images is essential in surgical procedures, such as pathological lesions or implant placement surgeries. In cone-beam computed-tomography images, the nasopalatine canal was examined in sagittal, coronal, and axial planes. The diameters of nasopalatine and incisive foramina were separately measured, and the length of the nasopalatine canal was found by measuring the distance between the mid-levels of the nasopalatine foramen and incisive foramen. The shape of the canal was assessed in the sagittal and coronal planes in the mid-level of the canal. In addition, the shape of the canal and posterior borders were examined in the mid-level of the canal in the axial plane. The nasopalatine angle was measured as an anterior angle between the long axis of the canal and the hard palate. The number of canals in the midline and openings in each plane was also counted. The nasopalatine canal in the sagittal plane was classified into six groups: conical (33.2%), cylindrical (25.6%), hourglass (24.7%), funnel-shaped (9.8%), reverse-cone (4.3%), and spindle (2.4%). In the coronal plane, the shape of the canal was assigned to three categories: single channel (59.2%), Y-shaped (31.2%), and dual-channel (9.6%), and the posterior border of the nasopalatine canal was classified into four groups: U-shaped (42.5%), V-shaped (37.2%), reverse-V-shaped (154%), and Y-shaped (4.9%). Finally, in the axial plane, the canal shape was classified into four groups: round (40.5%), oval (31.1%), heart-shaped (21.3%), and triangle-shaped (7%). The use of three-dimensional images should be strongly considered in all surgical interventions involving the nasopalatine canal, such as dental implant placement since any error in surgical interventions will bring about serious consequences due to higher aesthetic expectations for the anterior maxillary region. Due to the lack of correct diagnosis of canal morphology in conventional images, such as periapical and panoramic radiography, it seems necessary to use three-dimensional radiography when performing surgical interventions in this region.
{"title":"Anatomical characteristics of nasopalatine canal using cone beam computed tomography images","authors":"S. Panahi, G. Sabz, A. Jokartangkarami, S. Afroughi, F. Karimpour","doi":"10.56936/18290825-2022.16.1-101","DOIUrl":"https://doi.org/10.56936/18290825-2022.16.1-101","url":null,"abstract":"It is widely accepted that any interventional treatment, such as surgery, requires a precise and predetermined treatment plan. Moreover, conventional images do not allow for the presentation of all canal dimensions, and patients concepts of beauty and their expectations are greater for the premaxilla region. Therefore, the use of three-dimensional images is essential in surgical procedures, such as pathological lesions or implant placement surgeries.\u0000In cone-beam computed-tomography images, the nasopalatine canal was examined in sagittal, coronal, and axial planes. The diameters of nasopalatine and incisive foramina were separately measured, and the length of the nasopalatine canal was found by measuring the distance between the mid-levels of the nasopalatine foramen and incisive foramen. The shape of the canal was assessed in the sagittal and coronal planes in the mid-level of the canal. In addition, the shape of the canal and posterior borders were examined in the mid-level of the canal in the axial plane. The nasopalatine angle was measured as an anterior angle between the long axis of the canal and the hard palate. The number of canals in the midline and openings in each plane was also counted.\u0000The nasopalatine canal in the sagittal plane was classified into six groups: conical (33.2%), cylindrical (25.6%), hourglass (24.7%), funnel-shaped (9.8%), reverse-cone (4.3%), and spindle (2.4%). In the coronal plane, the shape of the canal was assigned to three categories: single channel (59.2%), Y-shaped (31.2%), and dual-channel (9.6%), and the posterior border of the nasopalatine canal was classified into four groups: U-shaped (42.5%), V-shaped (37.2%), reverse-V-shaped (154%), and Y-shaped (4.9%). Finally, in the axial plane, the canal shape was classified into four groups: round (40.5%), oval (31.1%), heart-shaped (21.3%), and triangle-shaped (7%).\u0000The use of three-dimensional images should be strongly considered in all surgical interventions involving the nasopalatine canal, such as dental implant placement since any error in surgical interventions will bring about serious consequences due to higher aesthetic expectations for the anterior maxillary region. Due to the lack of correct diagnosis of canal morphology in conventional images, such as periapical and panoramic radiography, it seems necessary to use three-dimensional radiography when performing surgical interventions in this region.","PeriodicalId":353660,"journal":{"name":"THE NEW ARMENIAN MEDICAL JOURNAL","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127295701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.56936/18290825-2022.16.1-29
T. Tajibayev, A. Chormanov, A. Matkerimov, A. Tergeussizov, A. Baubekov, M. Zhakubayev, I. Sagatov, M. Kanchi
Carotid body tumors, also commonly known as nonchromaffin paragangliomas and chemodectomas, is a slowly growing neoplasm originating from carotid body chemoreceptors. Herein we have presented a case series of surgical treatment of patients with carotid body tumors in National Scientific Center of Surgery named after AN Syzganov (2009-2020). Total number of patients was 10 with 11 neck mass, of which 7 (70%) were women, the average age was 47 (31-73) years, one case we faced with a bilateral location. The main complaint was slow-growing neck mass. On computed tomography angiography most of cases (70%) were of the 3th type according to the Shamblin grade with average size of 5.9 (4-8) cm. The main treatment was surgical excision in all cases. Mean duration of surgery 111.5 (75-190) min and hospital stay days 12.1(8-20) were registered. Total number of complications were 2 (20%), where in 1 case surgery complicated by bleeding more than 500 ml, and 1 patient presented dysphonia after the surgery, which resolved by time. Duration of surgery and hospital stay days were directly associated with size of mass and distance to base of skull. Pathology results showed that two patients (20%) had malignant cells, one of them with metastases to the nearest lymph nodes. Surgical resection is the treatment of choice for carotid body tumors. The large size of the masses and involvement of the carotid arteries and cranial nerves in the process directly affect the surgical approach and increase the risk of complications.
{"title":"Carotid body tumors: case series of extremely rare head and neck paragangliomas","authors":"T. Tajibayev, A. Chormanov, A. Matkerimov, A. Tergeussizov, A. Baubekov, M. Zhakubayev, I. Sagatov, M. Kanchi","doi":"10.56936/18290825-2022.16.1-29","DOIUrl":"https://doi.org/10.56936/18290825-2022.16.1-29","url":null,"abstract":"Carotid body tumors, also commonly known as nonchromaffin paragangliomas and chemodectomas, is a slowly growing neoplasm originating from carotid body chemoreceptors. Herein we have presented a case series of surgical treatment of patients with carotid body tumors in National Scientific Center of Surgery named after AN Syzganov (2009-2020). Total number of patients was 10 with 11 neck mass, of which 7 (70%) were women, the average age was 47 (31-73) years, one case we faced with a bilateral location. The main complaint was slow-growing neck mass. On computed tomography angiography most of cases (70%) were of the 3th type according to the Shamblin grade with average size of 5.9 (4-8) cm. The main treatment was surgical excision in all cases. Mean duration of surgery 111.5 (75-190) min and hospital stay days 12.1(8-20) were registered. Total number of complications were 2 (20%), where in 1 case surgery complicated by bleeding more than 500 ml, and 1 patient presented dysphonia after the surgery, which resolved by time. Duration of surgery and hospital stay days were directly associated with size of mass and distance to base of skull. Pathology results showed that two patients (20%) had malignant cells, one of them with metastases to the nearest lymph nodes. Surgical resection is the treatment of choice for carotid body tumors. The large size of the masses and involvement of the carotid arteries and cranial nerves in the process directly affect the surgical approach and increase the risk of complications.","PeriodicalId":353660,"journal":{"name":"THE NEW ARMENIAN MEDICAL JOURNAL","volume":"21 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134451968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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