Zhixiang Tao, Wei Zhao, Shang B Wang, Boyu Zhao, Rushuai Hua, Ji Qin, Zongwei Xu
{"title":"Annealing treatment of focused gallium ion beam processing of SERS gold substrate","authors":"Zhixiang Tao, Wei Zhao, Shang B Wang, Boyu Zhao, Rushuai Hua, Ji Qin, Zongwei Xu","doi":"10.1063/10.0007286","DOIUrl":"https://doi.org/10.1063/10.0007286","url":null,"abstract":"","PeriodicalId":35428,"journal":{"name":"Nami Jishu yu Jingmi Gongcheng/Nanotechnology and Precision Engineering","volume":" ","pages":""},"PeriodicalIF":3.7,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42066893","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Investigation into precision engineering design and development of the next-generation brake discs using Al/SiC metal matrix composites","authors":"J. Haley, K. Cheng","doi":"10.1063/10.0007289","DOIUrl":"https://doi.org/10.1063/10.0007289","url":null,"abstract":"","PeriodicalId":35428,"journal":{"name":"Nami Jishu yu Jingmi Gongcheng/Nanotechnology and Precision Engineering","volume":" ","pages":""},"PeriodicalIF":3.7,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45391094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Investigation of a dynamics-oriented engineering approach to ultraprecision\u0000 machining of freeform surfaces and its implementation perspectives","authors":"Ali Khaghani, K. Cheng","doi":"10.1063/10.0006388","DOIUrl":"https://doi.org/10.1063/10.0006388","url":null,"abstract":"","PeriodicalId":35428,"journal":{"name":"Nami Jishu yu Jingmi Gongcheng/Nanotechnology and Precision Engineering","volume":" ","pages":""},"PeriodicalIF":3.7,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41997360","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Biosensors have acquired much importance in drug discovery, medical diagnostics, food safety, defense, security, and monitoring of environmental conditions. Furthermore, there has been great progress in the potential applications of advanced nanomaterials in biosensors. Every year there are several advances in sensing techniques that can be attributed to nanomaterials, biorecognition elements, or their related fabrication techniques. The further development of nanotechnology-based sensors provides a wide variety of opportunities to modern research. Advanced nanomaterials can provide remarkable optical, electrical, mechanical, and catalytic properties. For example, transition metals and organic polymers have been used in the fabrication of powerful, sensitive, and precise biosensors. The distinctive properties of advanced nanomaterials have been widely incorporated into biosensors. However, fabrication techniques also play important roles in the development of these devices. Therefore, we present a review of some of the advanced nanomaterials that have been widely used over the last few years and discuss their fabrication techniques. The focus of this review is to provide a directional perspective of recently fabricated advanced nanomaterial-based biosensors in the diagnosis of various diseases.
{"title":"Recent advances in the design of biosensors based on novel nanomaterials: An insight","authors":"N. Chauhan, K. Saxena, Mayukh Tikadar, U. Jain","doi":"10.1063/10.0006524","DOIUrl":"https://doi.org/10.1063/10.0006524","url":null,"abstract":"Biosensors have acquired much importance in drug discovery, medical diagnostics, food safety, defense, security, and monitoring of environmental conditions. Furthermore, there has been great progress in the potential applications of advanced nanomaterials in biosensors. Every year there are several advances in sensing techniques that can be attributed to nanomaterials, biorecognition elements, or their related fabrication techniques. The further development of nanotechnology-based sensors provides a wide variety of opportunities to modern research. Advanced nanomaterials can provide remarkable optical, electrical, mechanical, and catalytic properties. For example, transition metals and organic polymers have been used in the fabrication of powerful, sensitive, and precise biosensors. The distinctive properties of advanced nanomaterials have been widely incorporated into biosensors. However, fabrication techniques also play important roles in the development of these devices. Therefore, we present a review of some of the advanced nanomaterials that have been widely used over the last few years and discuss their fabrication techniques. The focus of this review is to provide a directional perspective of recently fabricated advanced nanomaterial-based biosensors in the diagnosis of various diseases.","PeriodicalId":35428,"journal":{"name":"Nami Jishu yu Jingmi Gongcheng/Nanotechnology and Precision Engineering","volume":"4 1","pages":"045003"},"PeriodicalIF":3.7,"publicationDate":"2021-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44270363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The effects of the nonuniform cutting force and elastic recovery of processed materials in ultra-precision machining are too complex to be treated using traditional cutting theories, and it is necessary to take account of factors such as size effects, the undeformed cutting thickness, the tool blunt radius, and the tool rake angle. Therefore, this paper proposes a new theoretical calculation model for accurately predicting the cutting force in ultra-precision machining, taking account of such factors. The model is first used to analyze the material deformation of the workpiece and the cutting force distribution along the cutting edge of a diamond tool. The size of the strain zone in different cutting deformation zones is then determined by using the distribution of strain work per unit volume and considering the characteristics of the stress distribution in these different deformation zones. Finally, the cutting force during ultra-precision machining is predicted precisely by calculating the material strain energy in different zones. A finite element analysis and experimental data on ultra-precision cutting of copper and aluminum are used to verify the predictions of the theoretical model. The results show that the error in the cutting force between the calculation results and predictions of the model is less than 14%. The effects of the rake face stress distribution of the diamond tool, the close contact zone, and material elastic recovery can be fully taken into account by the theoretical model. Thus, the proposed theoretical calculation method can effectively predict the cutting force in ultra-precision machining.
{"title":"Prediction of cutting force in ultra-precision machining of nonferrous metals based on strain energy","authors":"Ying Wang, Z. Yuan, Tianzheng Wu, H. Yan","doi":"10.1063/10.0005648","DOIUrl":"https://doi.org/10.1063/10.0005648","url":null,"abstract":"The effects of the nonuniform cutting force and elastic recovery of processed materials in ultra-precision machining are too complex to be treated using traditional cutting theories, and it is necessary to take account of factors such as size effects, the undeformed cutting thickness, the tool blunt radius, and the tool rake angle. Therefore, this paper proposes a new theoretical calculation model for accurately predicting the cutting force in ultra-precision machining, taking account of such factors. The model is first used to analyze the material deformation of the workpiece and the cutting force distribution along the cutting edge of a diamond tool. The size of the strain zone in different cutting deformation zones is then determined by using the distribution of strain work per unit volume and considering the characteristics of the stress distribution in these different deformation zones. Finally, the cutting force during ultra-precision machining is predicted precisely by calculating the material strain energy in different zones. A finite element analysis and experimental data on ultra-precision cutting of copper and aluminum are used to verify the predictions of the theoretical model. The results show that the error in the cutting force between the calculation results and predictions of the model is less than 14%. The effects of the rake face stress distribution of the diamond tool, the close contact zone, and material elastic recovery can be fully taken into account by the theoretical model. Thus, the proposed theoretical calculation method can effectively predict the cutting force in ultra-precision machining.","PeriodicalId":35428,"journal":{"name":"Nami Jishu yu Jingmi Gongcheng/Nanotechnology and Precision Engineering","volume":"4 1","pages":"043001"},"PeriodicalIF":3.7,"publicationDate":"2021-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1063/10.0005648","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46006936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Intracellular delivery of functional molecules, such as DNA probes and plasmids, is an important method for investigating cellular mechanisms and changing cell fates in biomedicine. Among various delivery methods, recent years have seen the emergence of electroporation-based techniques that provide versatile platforms for molecule delivery, with high efficiency and controlled dosage. In this Review, we describe recent electroporation-based systems for intracellular molecule delivery. The principles of electroporation for cell membrane perforation and cargo delivery are briefly summarized. Focusing on various scenarios for the application of electroporation, we review electroporation devices that variously employ structures based on nanochannels, nanostraws, and flow-through microfluidic channels for in vitro intracellular molecule delivery. We also consider in vivo targeted therapies based on delivery of active molecules by electroporation according to the lesion locations. Finally, we discuss the current challenges facing electroporation-based techniques, as well as opportunities for their future development, which may lead to innovations in intracellular molecule delivery both for cellular analysis in the laboratory and treatment in the clinic.
{"title":"Recent electroporation-based systems for intracellular molecule delivery","authors":"Zaizai Dong, Lingqian Chang","doi":"10.1063/10.0005649","DOIUrl":"https://doi.org/10.1063/10.0005649","url":null,"abstract":"Intracellular delivery of functional molecules, such as DNA probes and plasmids, is an important method for investigating cellular mechanisms and changing cell fates in biomedicine. Among various delivery methods, recent years have seen the emergence of electroporation-based techniques that provide versatile platforms for molecule delivery, with high efficiency and controlled dosage. In this Review, we describe recent electroporation-based systems for intracellular molecule delivery. The principles of electroporation for cell membrane perforation and cargo delivery are briefly summarized. Focusing on various scenarios for the application of electroporation, we review electroporation devices that variously employ structures based on nanochannels, nanostraws, and flow-through microfluidic channels for in vitro intracellular molecule delivery. We also consider in vivo targeted therapies based on delivery of active molecules by electroporation according to the lesion locations. Finally, we discuss the current challenges facing electroporation-based techniques, as well as opportunities for their future development, which may lead to innovations in intracellular molecule delivery both for cellular analysis in the laboratory and treatment in the clinic.","PeriodicalId":35428,"journal":{"name":"Nami Jishu yu Jingmi Gongcheng/Nanotechnology and Precision Engineering","volume":"4 1","pages":"045001"},"PeriodicalIF":3.7,"publicationDate":"2021-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1063/10.0005649","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45377058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Molecular dynamics simulations are used to study the boundary lubrication behaviors of squalane lubricant between two iron wall structures during shearing at different pressures and temperatures. Boundary lubrication models with a smooth iron wall and a nanostructured iron wall, respectively, are constructed, and the density distribution of the lubricating film and the velocity distribution in the shearing process are analyzed. The mechanical response of the solid wall is output, and the friction coefficient is calculated. A tribological test is performed with a UMT-2 tribometer under sliding conditions to evaluate the reliability of the simulation method. The results show that the surface nanostructure has a significant effect on the film thickness and delamination of the lubricating film but little effect on the velocity distribution of the lubricating film. The nano strip groove helps to reduce the friction coefficient of the boundary lubrication system.
{"title":"Effects of surface nanostructure on boundary lubrication using molecular dynamics","authors":"Ling Pan, Hui-Chia Yu, Shiping Lu, G. Lin","doi":"10.1063/10.0005222","DOIUrl":"https://doi.org/10.1063/10.0005222","url":null,"abstract":"Molecular dynamics simulations are used to study the boundary lubrication behaviors of squalane lubricant between two iron wall structures during shearing at different pressures and temperatures. Boundary lubrication models with a smooth iron wall and a nanostructured iron wall, respectively, are constructed, and the density distribution of the lubricating film and the velocity distribution in the shearing process are analyzed. The mechanical response of the solid wall is output, and the friction coefficient is calculated. A tribological test is performed with a UMT-2 tribometer under sliding conditions to evaluate the reliability of the simulation method. The results show that the surface nanostructure has a significant effect on the film thickness and delamination of the lubricating film but little effect on the velocity distribution of the lubricating film. The nano strip groove helps to reduce the friction coefficient of the boundary lubrication system.","PeriodicalId":35428,"journal":{"name":"Nami Jishu yu Jingmi Gongcheng/Nanotechnology and Precision Engineering","volume":"4 1","pages":"033005"},"PeriodicalIF":3.7,"publicationDate":"2021-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1063/10.0005222","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42498813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Xue Wang, Z. Yuan, P. Zhuang, Tianzheng Wu, S. Feng
An innovative method for high-speed micro-dicing of SiC has been proposed using two types of diamond dicing blades, a resin-bonded dicing blade and a metal-bonded dicing blade. The experimental research investigated the radial wear of the dicing blade, the maximum spindle current, the surface morphology of the SiC die, the number of chips longer than 10 µm, and the chipped area, which depend on the dicing process parameters such as spindle speed, feed speed, and cutting depth. The chipping fractures in the SiC had obvious brittle fracture characteristics. The performance of the metal-bonded dicing blade was inferior to that of the resin-bonded dicing blade. The cutting depth has the greatest influence on the radial wear of the dicing blade, the maximum spindle current, and the damage to the SiC wafer. The next most important parameter is the feed speed. The parameter with the least influence is the spindle speed. The main factor affecting the dicing quality is blade vibration caused by spindle vibration. The optimal SiC dicing was for a resin-bonded dicing blade with a spindle speed of 20 000 rpm, a feed speed of 4 mm/s, and a cutting depth of 0.1 mm. To improve dicing quality and tool performance, spindle vibrations should be reduced. This approach may enable high-speed dicing of SiC wafers with less dicing damage.
{"title":"Study on precision dicing process of SiC wafer with diamond dicing blades","authors":"Xue Wang, Z. Yuan, P. Zhuang, Tianzheng Wu, S. Feng","doi":"10.1063/10.0005152","DOIUrl":"https://doi.org/10.1063/10.0005152","url":null,"abstract":"An innovative method for high-speed micro-dicing of SiC has been proposed using two types of diamond dicing blades, a resin-bonded dicing blade and a metal-bonded dicing blade. The experimental research investigated the radial wear of the dicing blade, the maximum spindle current, the surface morphology of the SiC die, the number of chips longer than 10 µm, and the chipped area, which depend on the dicing process parameters such as spindle speed, feed speed, and cutting depth. The chipping fractures in the SiC had obvious brittle fracture characteristics. The performance of the metal-bonded dicing blade was inferior to that of the resin-bonded dicing blade. The cutting depth has the greatest influence on the radial wear of the dicing blade, the maximum spindle current, and the damage to the SiC wafer. The next most important parameter is the feed speed. The parameter with the least influence is the spindle speed. The main factor affecting the dicing quality is blade vibration caused by spindle vibration. The optimal SiC dicing was for a resin-bonded dicing blade with a spindle speed of 20 000 rpm, a feed speed of 4 mm/s, and a cutting depth of 0.1 mm. To improve dicing quality and tool performance, spindle vibrations should be reduced. This approach may enable high-speed dicing of SiC wafers with less dicing damage.","PeriodicalId":35428,"journal":{"name":"Nami Jishu yu Jingmi Gongcheng/Nanotechnology and Precision Engineering","volume":"4 1","pages":"033004"},"PeriodicalIF":3.7,"publicationDate":"2021-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1063/10.0005152","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46977308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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