Sunita K. Shere, Anjali S. Kulkarni, Shubhjyoti Pore, R. Bindu
Testicular fibroma of gonadal stromal origin is a rare benign tumor of testis, which usually presents as a slow growing testicular mass. Intratesticular fibroma of gonadal stromal origin, with or without minor sex cord elements, must be considered, analogous to similar tumors in ovary, as a benign tumor. Until now, only 25 cases of testicular fibroma have been reported in the literature. We reported a case of testicular fibroma in a 20 years male who presented with painless right testicular enlargement since two years. Ultrasonography (USG) showed heterogeneous mass in right scrotum suggestive of testicular malignancy. Right orchidectomy was done. Histopathological diagnosis was testicular fibroma, which was confirmed by immunohistochemistry.
{"title":"Testicular fibroma: A case report","authors":"Sunita K. Shere, Anjali S. Kulkarni, Shubhjyoti Pore, R. Bindu","doi":"10.2298/AOO1304139S","DOIUrl":"https://doi.org/10.2298/AOO1304139S","url":null,"abstract":"Testicular fibroma of gonadal stromal origin is a rare benign tumor of testis, which usually presents as a slow growing testicular mass. Intratesticular fibroma of gonadal stromal origin, with or without minor sex cord elements, must be considered, analogous to similar tumors in ovary, as a benign tumor. Until now, only 25 cases of testicular fibroma have been reported in the literature. We reported a case of testicular fibroma in a 20 years male who presented with painless right testicular enlargement since two years. Ultrasonography (USG) showed heterogeneous mass in right scrotum suggestive of testicular malignancy. Right orchidectomy was done. Histopathological diagnosis was testicular fibroma, which was confirmed by immunohistochemistry.","PeriodicalId":35645,"journal":{"name":"Archive of Oncology","volume":"21 1","pages":"139-140"},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68402517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hodgkin lymphoma and anaplastic large cell lymphoma are malignancies that highly express CD30 antigen on the cell surface. Both are generally curable by standard chemotherapy but refractory diseases and relapses are treatment problems. Brentuximab-vedotin is a labeled monoclonal antibody against CD30 and it is approved for the treatment of Hodgkin lymphoma relapsed after autologous stem cell transplantation and for relapsed anaplastic large cell lymphoma. This is the first drug approved for the treatment of Hodgkin lymphoma after 30 years.
{"title":"CD30 - the head of TNF-family… or a successful story of brentuximab vedotin","authors":"L. Popović, D. Jovanović, Ðordje Popovic","doi":"10.2298/AOO1301017P","DOIUrl":"https://doi.org/10.2298/AOO1301017P","url":null,"abstract":"Hodgkin lymphoma and anaplastic large cell lymphoma are malignancies that highly express CD30 antigen on the cell surface. Both are generally curable by standard chemotherapy but refractory diseases and relapses are treatment problems. Brentuximab-vedotin is a labeled monoclonal antibody against CD30 and it is approved for the treatment of Hodgkin lymphoma relapsed after autologous stem cell transplantation and for relapsed anaplastic large cell lymphoma. This is the first drug approved for the treatment of Hodgkin lymphoma after 30 years.","PeriodicalId":35645,"journal":{"name":"Archive of Oncology","volume":"21 1","pages":"17-19"},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2298/AOO1301017P","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68401703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
D. Dobanovacki, M. Breberina, B. Vujošević, M. Pećanac, Nenad Zakula, Velimir Trajkovic
Following the shift in therapy of tuberculosis in the mid-19th century, by the beginning of the 20th century numerous tuberculosis sanatoria were established in Western Europe. Being an institutional novelty in the medical practice, sanatoria spread within the first 20 years of the 20th century to Central and Eastern Europe, including the southern region of the Panonian plain, the present-day Province of Vojvodina in Serbia north of the rivers Sava and Danube. The health policy and regulations of the newly built state - the Kingdom of Serbs, Croats and Slovenians/Yugoslavia, provided a rather liberal framework for introducing the concept of sanatorium. Soon after the World War I there were 14 sanatoria in this region, and the period of their expansion was between 1920 and 1939 when at least 27 sanatoria were founded, more than half of the total number of 46 sanatoria in the whole state in that period. However, only two of these were for pulmonary diseases. One of them was privately owned the open public sanatorium the English-Yugoslav Hospital for Paediatric Osteo-Articular Tuberculosis in Sremska Kamenica, and the other was state-run (at Iriski venac, on the Fruska Gora mountain, as a unit of the Department for Lung Disease of the Main Regional Hospital). All the others were actually small private specialized hospitals in 6 towns (Novi Sad, Subotica, Sombor, Vrbas, Vrsac, Pancevo,) providing medical treatment of well-off, mostly gynaecological and surgical patients. The majority of sanatoria founded in the period 1920-1939 were in or close to the city of Novi Sad, the administrative headquarters of the province (the Danube Banovina at that time) with a growing population. A total of 10 sanatoria were open in the city of Novi Sad, with cumulative bed capacity varying from 60 to 130. None of these worked in newly built buildings, but in private houses adapted for medical purpose in accordance with legal requirements. The decline of sanatoria in Vojvodina began with the very outbreak of the World War II and they never regained their social role. Soon after the Hungarian fascist occupation the majority of owners/ founders were terrorized and forced to close their sanatoria, some of them to leave country and some were even killed or deported to concentration camps.
{"title":"Sanatoria in the first half of the XX century in the Province of Vojvodina","authors":"D. Dobanovacki, M. Breberina, B. Vujošević, M. Pećanac, Nenad Zakula, Velimir Trajkovic","doi":"10.2298/AOO1301034D","DOIUrl":"https://doi.org/10.2298/AOO1301034D","url":null,"abstract":"Following the shift in therapy of tuberculosis in the mid-19th century, by the beginning of the 20th century numerous tuberculosis sanatoria were established in Western Europe. Being an institutional novelty in the medical practice, sanatoria spread within the first 20 years of the 20th century to Central and Eastern Europe, including the southern region of the Panonian plain, the present-day Province of Vojvodina in Serbia north of the rivers Sava and Danube. The health policy and regulations of the newly built state - the Kingdom of Serbs, Croats and Slovenians/Yugoslavia, provided a rather liberal framework for introducing the concept of sanatorium. Soon after the World War I there were 14 sanatoria in this region, and the period of their expansion was between 1920 and 1939 when at least 27 sanatoria were founded, more than half of the total number of 46 sanatoria in the whole state in that period. However, only two of these were for pulmonary diseases. One of them was privately owned the open public sanatorium the English-Yugoslav Hospital for Paediatric Osteo-Articular Tuberculosis in Sremska Kamenica, and the other was state-run (at Iriski venac, on the Fruska Gora mountain, as a unit of the Department for Lung Disease of the Main Regional Hospital). All the others were actually small private specialized hospitals in 6 towns (Novi Sad, Subotica, Sombor, Vrbas, Vrsac, Pancevo,) providing medical treatment of well-off, mostly gynaecological and surgical patients. The majority of sanatoria founded in the period 1920-1939 were in or close to the city of Novi Sad, the administrative headquarters of the province (the Danube Banovina at that time) with a growing population. A total of 10 sanatoria were open in the city of Novi Sad, with cumulative bed capacity varying from 60 to 130. None of these worked in newly built buildings, but in private houses adapted for medical purpose in accordance with legal requirements. The decline of sanatoria in Vojvodina began with the very outbreak of the World War II and they never regained their social role. Soon after the Hungarian fascist occupation the majority of owners/ founders were terrorized and forced to close their sanatoria, some of them to leave country and some were even killed or deported to concentration camps.","PeriodicalId":35645,"journal":{"name":"Archive of Oncology","volume":"21 1","pages":"34-43"},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2298/AOO1301034D","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68401847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
D. Dobanovacki, N. Vuckovic, S. Marinković, J. Kolarovic, Svetlana Stefanovic-Saravolac
We described two cases of infantile hepatic hemangioendothelioma: one with a solitary lesion and the other with multicentric lesions. Clinical presentation was with no liver symptoms in case 1, and hepatomegaly, failure to thrive, and palpable abdominal mass in case 2. Diagnostic imaging revealed single tumor formation in case 1 and multiple nodules in the liver in case 2. Dilemmas related to nature of the tumor were solved by microscopic analysis. The patient with the clinical appearance of a single lesion was successfully operated. The patient with multiple lesions in the liver tissue showed complete involution after corticotherapy.
{"title":"Infantile hepatic hemangioendothelioma: Report of two cases","authors":"D. Dobanovacki, N. Vuckovic, S. Marinković, J. Kolarovic, Svetlana Stefanovic-Saravolac","doi":"10.2298/AOO1302072D","DOIUrl":"https://doi.org/10.2298/AOO1302072D","url":null,"abstract":"We described two cases of infantile hepatic hemangioendothelioma: one with a solitary lesion and the other with multicentric lesions. Clinical presentation was with no liver symptoms in case 1, and hepatomegaly, failure to thrive, and palpable abdominal mass in case 2. Diagnostic imaging revealed single tumor formation in case 1 and multiple nodules in the liver in case 2. Dilemmas related to nature of the tumor were solved by microscopic analysis. The patient with the clinical appearance of a single lesion was successfully operated. The patient with multiple lesions in the liver tissue showed complete involution after corticotherapy.","PeriodicalId":35645,"journal":{"name":"Archive of Oncology","volume":"21 1","pages":"72-76"},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2298/AOO1302072D","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68401990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The importance of an up-to-date evidence based diet planning for colorectal cancer patients","authors":"I. Banjari, Josipa Fako","doi":"10.2298/AOO1304160B","DOIUrl":"https://doi.org/10.2298/AOO1304160B","url":null,"abstract":"","PeriodicalId":35645,"journal":{"name":"Archive of Oncology","volume":"21 1","pages":"160-162"},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68402150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
In this paper, the author considers the enterprise of fasting, in which the man faces the important issues of his existence, the purpose and worldly life. The author is aware that all social, philosophical and theological phenomena are very complex, profound and obscure and quotes the French philosopher and scientist Pascal, who claimed: “We do not possess enough knowledge to…understand the life of human body…While in nature everything is closely intertwined … No part can be recognized unless we have studied the unit. The life of each body will be understood only when we learn all that it needs; and in order to achieve this, it is necessary to study the universe. But the universe is infinite and it is beyond the human ability to grasp it…”It is clear from this quotation that we are facing many complex issues whenever we try to reveal one of the secrets of Christian life - the secret of fasting. The second part of the essay has to do with people and the time we live in, the relations between believing doctors and their profession and whether and to what extent a believing doctor who observes fasts is closer to the Truth and Goodness that the one who does not believe. The author argues that the doctor who is a believer and who observes a fast seeing it as the time when values of human life should be put to test and the meaning of medical profession reconsidered is closer to the truth of Existence and love of the world. There is no duty that is more important for a modern, egotistic, materialistic man than resuming fasts. A fast as a profound rethinking of the whole of a human being, as a human effort, as Solzhenitsyn would say, to self-restriction, abstinence, nurturing of his own freedom.
{"title":"Enterprise of fasting and vocation of a physician","authors":"Ilija Kajtez","doi":"10.2298/AOO1301044K","DOIUrl":"https://doi.org/10.2298/AOO1301044K","url":null,"abstract":"In this paper, the author considers the enterprise of fasting, in which the man faces the important issues of his existence, the purpose and worldly life. The author is aware that all social, philosophical and theological phenomena are very complex, profound and obscure and quotes the French philosopher and scientist Pascal, who claimed: “We do not possess enough knowledge to…understand the life of human body…While in nature everything is closely intertwined … No part can be recognized unless we have studied the unit. The life of each body will be understood only when we learn all that it needs; and in order to achieve this, it is necessary to study the universe. But the universe is infinite and it is beyond the human ability to grasp it…”It is clear from this quotation that we are facing many complex issues whenever we try to reveal one of the secrets of Christian life - the secret of fasting. The second part of the essay has to do with people and the time we live in, the relations between believing doctors and their profession and whether and to what extent a believing doctor who observes fasts is closer to the Truth and Goodness that the one who does not believe. The author argues that the doctor who is a believer and who observes a fast seeing it as the time when values of human life should be put to test and the meaning of medical profession reconsidered is closer to the truth of Existence and love of the world. There is no duty that is more important for a modern, egotistic, materialistic man than resuming fasts. A fast as a profound rethinking of the whole of a human being, as a human effort, as Solzhenitsyn would say, to self-restriction, abstinence, nurturing of his own freedom.","PeriodicalId":35645,"journal":{"name":"Archive of Oncology","volume":"31 1","pages":"44-49"},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2298/AOO1301044K","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68401905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Struma ovarii is composed of thyroid tissue originated from germ cells in a mature teratoma. Thyroid carcinoma found in struma ovarii is very rare. Primary thyroid carcinoma should be excluded. We present a 62-year-old female with papillary thyroid carcinoma in a mature teratoma as a incidentally found diagnosis. The patient underwent the surgery because of the endometrial carcinoma, while the histopathological examination found endometrial carcinoma as well as malignant struma ovarii. From the surgical point of view, it is very important to evaluate thyroid gland status in patients with malignant struma ovarii.
{"title":"Papillary thyroid cancer found in struma ovarii: A case report","authors":"I. Majdevac, D. Lukić, M. Ranisavljevic","doi":"10.2298/AOO1304141M","DOIUrl":"https://doi.org/10.2298/AOO1304141M","url":null,"abstract":"Struma ovarii is composed of thyroid tissue originated from germ cells in a mature teratoma. Thyroid carcinoma found in struma ovarii is very rare. Primary thyroid carcinoma should be excluded. We present a 62-year-old female with papillary thyroid carcinoma in a mature teratoma as a incidentally found diagnosis. The patient underwent the surgery because of the endometrial carcinoma, while the histopathological examination found endometrial carcinoma as well as malignant struma ovarii. From the surgical point of view, it is very important to evaluate thyroid gland status in patients with malignant struma ovarii.","PeriodicalId":35645,"journal":{"name":"Archive of Oncology","volume":"21 1","pages":"141-142"},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68402530","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Stupar, V. Vidović, V. Baltic, Ljuba Štrbac, D. Lukač
We are starting to understand the fundamental biological processes which underlie the DNA physical properties. Of particular importance is the field of epigenetics, which literally means 'outside conventional genetics', now used to describe the study of stable alterations in gene expression potential that arise during development and cell proliferation. Epigenetic changes are modifications of DNA, which occur without any alteration in the DNA sequence. Modern directions in the field of epigenetic research aimed to decipher the epigenetic signals that give stem cells their unique ability to self-renew and differentiate into different types. Stem cell-based regenerative medicine holds great promise for repair of diseased tissue. If epigenetic process are reversible, than there is the ability to cure cancer through stem cell therapy.
{"title":"Epigenetic DNA changes and stem cells therapy","authors":"M. Stupar, V. Vidović, V. Baltic, Ljuba Štrbac, D. Lukač","doi":"10.2298/AOO1301024S","DOIUrl":"https://doi.org/10.2298/AOO1301024S","url":null,"abstract":"We are starting to understand the fundamental biological processes which underlie the DNA physical properties. Of particular importance is the field of epigenetics, which literally means 'outside conventional genetics', now used to describe the study of stable alterations in gene expression potential that arise during development and cell proliferation. Epigenetic changes are modifications of DNA, which occur without any alteration in the DNA sequence. Modern directions in the field of epigenetic research aimed to decipher the epigenetic signals that give stem cells their unique ability to self-renew and differentiate into different types. Stem cell-based regenerative medicine holds great promise for repair of diseased tissue. If epigenetic process are reversible, than there is the ability to cure cancer through stem cell therapy.","PeriodicalId":35645,"journal":{"name":"Archive of Oncology","volume":"21 1","pages":"24-27"},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2298/AOO1301024S","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68401790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Bacterial flora on the surface of oral squamous cell carcinoma","authors":"M. Čanković, M. Bokor-Bratić, J. Loncar, Jovan Marinoski, M. Ilić","doi":"10.2298/AOO1302062C","DOIUrl":"https://doi.org/10.2298/AOO1302062C","url":null,"abstract":"4 patients (13.3%), mucocele in 4 patients (13.3%), capillary mucous haemangioma in 3 patients (10.0%), mucosal polyp in 3 patients (10.0%), chronic nonspecific sialadenitis in 3 patients (10.0%), mucosal papilloma in 2 patients (6.7%), retention cyst in 2 patients (6.7%), and subacute nonspecific inflammation in 1 patient (3.3%).","PeriodicalId":35645,"journal":{"name":"Archive of Oncology","volume":"21 1","pages":"62-64"},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2298/AOO1302062C","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68401933","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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