Journal of Contemporary Dental Practice最新文献

Aim: The aim of the current study was to assess the effectiveness of three remineralizing agents on demineralized enamel following the debonding of orthodontic brackets.

Materials and methods: Sixty healthy human premolar teeth that were extracted during orthodontic treatment were bonded with brackets and kept in deionized water for a week. Later, they were debonded, and the residual composite was removed with finishing discs and were subjected to pH cycling for 14 days at 37°C to replicate the oral cavity environment. Samples were submerged in a demineralizing solution for 14 days. All 60 teeth were randomly divided into three groups (n = 20)-group I: Application of Toothmin agent, group II: Application of casein phosphopeptide-amorphous calcium phosphate (CPP-ACP), and group III: Application of Amflor toothpaste. A scanning electron microscope was used to investigate for the enamel surface demineralization. All data were recorded and statistically analyzed.

Results: At baseline, the mean enamel demineralized area was 118.26 ± 0.16 in the Toothmin agent group, 119.08 ± 0.09 in the CPP-ACP agent group, and 117.80 ± 0.10 in the Amflor toothpaste group. The maximum reduction of the demineralized area was found in the CPP-ACP agent group with a mean value of 101.20 ± 0.12 followed by the Toothmin agent group with a mean value of 104.46 ± 0.06 and the Amflor toothpaste group with a mean value of 110.80 ± 0.10. A significant difference was found between the groups.

Conclusion: The present study concluded that the CPP-ACP agent group had the greatest reduction in demineralized area when compared to the Toothmin agent group and the Amflor toothpaste group.

Clinical significance: After orthodontic treatment, demineralized areas frequently appear on the labial surfaces of teeth. As a result, these lesions present esthetic difficulties, which impact the patient's perception of treatment satisfaction. Because esthetics and appearance are of the highest importance following orthodontic treatment, elimination techniques for remineralization of demineralized regions must be implemented economically. How to cite this article: Khargekar NR, Dash KC, Sam G, et al. Evaluation of the Efficacy of Three Remineralizing Agents on Demineralized Enamel after Orthodontic Brackets Debonding: A Comparative Study. J Contemp Dent Pract 2026;27(1):33-36.

Aim: The aim of the present study was to evaluate surface texture (ST) and clinical performance (CP) of milled biocompatible high-performance polymer (BioHPP) polyetheretherketone (PEEK) single posterior crowns veneered with two different techniques.

Materials and methods: A total of 32 patients requiring posterior crowns were divided randomly into two equal groups (n = 16) according to the veneering technique used. The manual group included patients receiving milled BioHPP PEEK copings veneered with manual layering, and the computer-aided designing (CAD)/computer-aided manufacturing (CAM) group included patients receiving milled BioHPP PEEK copings veneered with CAD/CAM composite resin [high impact performance composite (HIPC)]. Surface texture and CP were evaluated at cementation time and every 6 months for 1-year follow-up period.

Results: Both veneering techniques performed comparably in terms of maintaining ST and CP for 1-year follow-up. Regarding ST, the results (p = 0.8993) indicated that there was no statistically significant difference in the survival patterns between the two groups over the study period. Also, for CP, there was no statistically significant difference (p > 0.9999) between the CAD/CAM composite resin veneered and manually veneered BioHPP PEEK copings over the study period.

Conclusion: Milled BioHPP PEEK copings veneered with manual veneering and CAD/CAM composite resin veneering showed clinically accepted ST and CP after 1 year of follow-up.

Clinical significance: Polyetheretherketone veneered crowns are a valid treatment option for restoring posterior endodontically treated teeth when properly finished and polished following the manufacturer's recommendation. How to cite this article: Dief AK, Elshehy O, Nabil O. Surface Texture and Clinical Performance of Milled BioHPP Polyetheretherketone (PEEK) Single Posterior Crowns Veneered with Two Different Techniques: Randomized Controlled Clinical Trial. J Contemp Dent Pract 2026;27(1):67-77.

Aim: The study aimed to estimate the prevalence of dental caries and its associated factors among adults in Jizan, Saudi Arabia.

Methods: A cross-sectional study was conducted among 567 adults aged 19 years and above recruited from governmental hospital dental clinics. Data were collected via a questionnaire consisting of 17 questions. It included nine questions on sociodemographic characteristics and eight questions on oral health behaviors, such as toothbrushing, toothpaste containing fluoride, tongue cleaning, visiting the dentist, and smoking, along with direct oral examinations using the decayed, missing, and filled teeth (DMFT) index. Adjusted odds ratio (aOR) was used as a measure of association, with 95% confidence interval (CI). A p < 0.05 was considered statistically significant.

Results: The overall prevalence of dental caries was 79.4%. Multivariable analysis revealed significant associations between prevalence of dental caries and residing in rural areas (aOR = 4.45, 95% CI: 2.32-8.55, p < 0.001), having a high school education or below (aOR = 11.66, 95% CI: 3.55-38.31, p < 0.001), not brushing teeth (aOR = 3.60, 95% CI: 1.77-7.32, p < 0.001), not using fluoride-containing toothpaste (aOR = 5.36, 95% CI: 2.48-11.55, p < 0.001), delayed toothbrush replacement (more than 2 months: aOR = 23.25, 95% CI: 8.05-67.13, p < 0.001; when bristles flared: aOR = 3.09, 95% CI: 1.42-6.72, p = 0.004), infrequent tongue cleaning (aOR = 11.53, 95% CI: 5.04-26.40, p < 0.001), and smoking (aOR = 2.77, 95% CI: 1.41-5.42, p = 0.003).

Conclusion: A high prevalence of dental caries (79.4%) was found among adults in Jizan, Kingdom of Saudi Arabia (KSA). Key contributing factors included rural residence, lower education, not brushing/fluoride toothpaste, delayed toothbrush replacement, infrequent tongue cleaning, and smoking.

Clinical significance: The significant variation and limited current data on dental caries prevalence and associated determinants in the Jizan region of KSA indicate a crucial need for this study. Identifying key factors behind this public health issue is essential for guiding effective local and national oral health strategies. The findings provide vital data that can be used for the clinical translational value of designing targeted interventions and informing local oral health policy to ultimately improve oral health outcomes for adults in the Jizan area. How to cite this article: Shubayr MA, Boreak N, Alhuraysi SM, et al. Oral Health Behavior Factors Associated with Dental Caries among Adults in Jizan, Kingdom of Saudi Arabia: A Cross-sectional Study. J Contemp Dent Pract 2026;27(1):59-66.

Aim: Gingival recession (GR) is a significant determinant of both the functional and cosmetic aspects of patients. Guided tissue regeneration (GTR) using collagen membranes is considered a desirable option among the various strategies for GR coverage using barrier membranes. Therefore, this clinical research was carried out to evaluate the effectiveness of GTR using bioabsorbable collagen membrane (GTRbcm) and subepithelial connective tissue graft (SCTG) in the treatment of GR over a duration of 6 months.

Materials and methods: A total of 24 patients diagnosed with Miller's class I and II GR participated in a double-blind, randomized controlled trial, which was divided into two groups, with 12 patients in each group. Group I received a coronally advanced flap (CAF) with GTR, whereas group II had CAF with SCTG following the first periodontal treatment. Paired t-tests and analysis of covariance (ANCOVA) were used for evaluating parameters within and across groups.

Results: Analysis of covariance revealed that the recession depth (RD) in group I was significantly greater than in group II at 3 months (1.27 ± 0.17 compared to 0.65 ± 0.17) and 6 months (1.06 ± 0.16 compared to 0.19 ± 0.16), respectively. Group II had a more substantial reduction in RD, with a reduction of 74, 83, and 95% observed at all subsequent examinations.

Conclusions: The findings of this study indicate that both surgical procedures may effectively treat Miller's class I and II GRs, resulting in satisfactory root coverage.

Clinical significance: The GTR technique with collagen membrane can be an alternative to the SCTG in the management of GR. It will help clinicians in evidence-based decision-making and careful case selection for successful outcomes in treating GR. How to cite this article: Siddiqui LT, Amirisetty R, Shetty RM, et al. Guided Tissue Regeneration and Subepithelial Connective Tissue Graft in the Treatment of Gingival Recession: A Randomized Clinical Trial. J Contemp Dent Pract 2026;27(1):12-20.

Aim: The current study aimed to assess the bond strength at the resin interface following deciduous teeth with three dentine biomodifiers.

Materials and methods: The study employed a total of 75 primary non-carious molars. The buccal surface of the teeth was prepped for class V cavities, with the cervical borders placed 0.75 mm apical to the CEJ and the occlusal edge in the enamel. Each cavity measured 1.5 mm in depth, 4 mm in width, and 4 mm in length. All samples were randomly allocated to one of the following groups, with 25 samples in each group-group I: application of chitosan nanoparticles, group II: application of hesperidin solution, group III: application of casein phosphopeptide-amorphous calcium phosphate (CPP-ACP). For every sample, adhesive was applied. A universal testing machine was used to assess the shear bond strength. Data were recorded and statistically analyzed.

Results: The casein phosphopeptide-amorphous calcium phosphate group at 146.16 ± 1.01 showed the maximum shear bond strength, followed by the chitosan nanoparticles group at 142.74 ± 0.98 and the hesperidin solution at 128.26 ± 0.74. A statistically significant difference was found among the three groups.

Conclusion: The present study concluded that the CPP-ACP group exhibited the maximum shear bond strength compared to the chitosan nanoparticles group and the hesperidin solution group.

Clinical significance: Dentin biomodification has been highlighted as a way to strengthen the binding between composite resin and the tooth surface, hence extending its lifespan. By adding dentin biomodifiers to dental adhesives, the stability of the resin-dentin interface may be improved, and MMP inhibitory capacity may be added. How to cite this article: Maheshappa SK, Bagchi A, Bankur PK, et al. Evaluation of the Shear Bond Strength at Resin Interface after Pretreatment with Three Dentine Biomodifiers on Primary Teeth: An In Vitro Study. J Contemp Dent Pract 2026;27(1):1-4.

Aim: This study aims to examine the pro-apoptotic and anti-migratory effects of Berberine in KB-1 oral cancer cells and its role in ferroptosis via glutathione peroxidase4/six-transmembrane epithelial antigen of prostate3 (GPX4/STEAP3) signaling pathway.

Materials and methods: KB-1 cells were treated with Berberine, and cell viability was assessed using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay. Morphological changes were analyzed via phase-contrast microscopy, while nuclear fragmentation was examined using acridine orange/ethidium bromide (AO/EtBr) staining. Molecular docking, gene expression analyses were performed to assess ferroptosis markers. Wound healing and migration assays evaluated Berberine's effect on cell migration.

Results: Berberine reduced cell viability (IC50: 22.2 μM) and induced morphological changes, including shrinkage and membrane blebbing. AO/EtBr staining confirmed nuclear fragmentation. Gene expression analysis showed ferroportin upregulation and GPX4, STEAP3, and transferrin receptor 1 (TFR1) downregulation, validated by western blotting. Molecular docking confirmed strong Berberine binding, particularly with GPX4 and STEAP3. Wound healing and migration assays showed significant migration suppression. All experimental data were statistically evaluated using the Student's t-test and one-way ANOVA.

Conclusion: Berberine induces ferroptosis and inhibits KB-1 oral cancer cell proliferation and migration by modulating the ferroptosis signaling pathway, suggesting its potential as a novel therapeutic agent.

Clinical significance: By promoting iron-dependent cell death and suppressing migratory capacity, Berberine may overcome resistance to conventional therapies and reduce metastatic progression. Its natural origin and prior safety profile support drug repurposing opportunities, though challenges such as poor bioavailability and systemic toxicity must be addressed. These findings provide a foundation for biomarker-driven preclinical and early clinical evaluations. How to cite this article: Alassiri S. Berberine Induces Ferroptosis and Impairs Migration via Glutathione Peroxidase4/Six-transmembrane Epithelial Antigen of Prostate3 Signaling Pathway in Oral Cancer Cells. J Contemp Dent Pract 2025;26(11):1050-1059.

Aim: Despite the widespread availability of online information about dental veneers, there is a lack of data on the quality and readability of these resources. The aim of this study was to assess the quality and readability of patient-oriented online information on dental veneers.

Materials and methods: This study conducted a thorough web search utilizing Google, Yahoo, and Bing search engines to identify English-language websites offering information on dental veneers. The quality of the websites was assessed using DISCERN, Journal of the American Medical Association (JAMA) benchmarks, and Health on the Net Code (HONcode) tools. The readability of the websites was evaluated using the Flesch-Kincaid Grade Level (FKGL), Simplified Measure of Gobbledygook (SMOG), and Flesch Reading Ease (FRE) metrics.

Results: Out of a total of 195 websites included in the study, only 8 websites obtained a high overall DISCERN score, representing 2.4% of dental clinic (DC) and 14.8% of nonprofit organization (NPO) websites. The median [interquartile range (IQR)] of the overall score of DISCERN was significantly higher for NPO websites [55.5 (13)] compared to DC websites [42 (13)] and commercial entity (CE) websites [36.25 (5.5); p < 0.001]. Up to 15, 63, and 70% of NPO, DC, and CE websites, respectively, did not report any of the four JAMA criteria. Only seven websites (all NPOs) showed an active Health on the Net (HONs) Code certificate. All readability indicators confirmed easier texts on the NPO websites.

Conclusions: The quality of the English web-based health information on dental veneers seems suboptimal. Nonprofit organization websites offer higher quality, more reliable, and readable content compared to DC and CE websites.

Clinical significance: Online dental veneer information is generally of poor quality, with NPO websites offering the most reliable and readable content. Clinicians should direct patients to trustworthy NPO resources for accurate information. How to cite this article: Alqutaibi AY, Alharbi AT, Alassaf MS, et al. Assessment of Quality and Readability of Online Patient-centered Information on Dental Veneers: An Infodemiological Study. J Contemp Dent Pract 2025;26(11):1060-1066.

Aim: To evaluate the role of erbium lasers (Er:YAG and Er,Cr:YSGG) as adjuncts in access flap periodontal surgery and their potential contribution to personalized, minimally invasive periodontal care.

Background: Periodontal surgery has progressively evolved toward minimally invasive techniques prioritizing tissue preservation, enhanced healing, and reduced morbidity. Erbium lasers represent a significant advancement by offering precise tissue ablation, improved decontamination, and favorable patient experiences compared to conventional approaches.

Review results: Evidence shows that erbium lasers achieve clinical outcomes comparable to or better than traditional flap surgery. Benefits include reduced postoperative discomfort, minimized gingival recession (GR), and enhanced patient satisfaction. While gains in clinical attachment level are modest yet statistically significant in some studies, patient-reported outcomes (PROs) consistently favor erbium-assisted interventions.

Conclusion: Erbium lasers enhance access flap surgery by supporting precision, soft tissue preservation, and improved patient-centered outcomes. Current data suggest they are valuable adjuncts, though long-term trials are still needed to establish standardized protocols.

Clinical significance: Integration of erbium lasers into periodontal flap surgery supports personalized and minimally invasive care, aligning with modern principles of precision periodontics and improving both clinical and PROs. How to cite this article: Neophytou C, Neofytou AM, Davidopoulou S, et al. Erbium Laser-assisted Access Flap Periodontal Surgery: Advancing Personalized Periodontal Care through Minimally Invasive Technologies. J Contemp Dent Pract 2025;26(11):1025-1034.

Aim: This study aimed to evaluate in vitro the effect of a natural mouthrinse and alcohol-free 0.12% chlorhexidine on force degradation of orthodontic elastomeric chains from four commercial brands: Ormco Generation II Power Chain, TP E-Chain, American Orthodontics, and Morelli.

Materials and methods: An experimental design was employed using 108 samples, divided into three groups: Control, chlorhexidine, and natural rinse. Force measurements were taken at baseline, after 24 hours, and after 30 days using a high-precision digital dynamometer. Data were analyzed using a three-way ANOVA (Brand × Rinse × Time) and a multiple linear regression model, with significance set at p < 0.05.

Results: The findings revealed a biphasic degradation pattern, characterized by a sharp decline in force during the first 24 hours, followed by a more gradual reduction over the next 30 days. Among the brands, TP demonstrated the lowest force degradation compared to Ormco (approximately -9.79 percentage points), while American Orthodontics and Morelli showed significantly higher losses (approximately +17.31 and +16.17 percentage points, respectively). Exposure to chlorhexidine increased degradation (approximately +4.66 percentage points), whereas the natural mouth rinse did not have a significant overall effect. Additionally, time was a crucial factor: After 30 days, degradation increased by approximately +2.41 percentage points compared to the 24-hour mark.

Conclusion: Degradation of elastomeric chains is influenced by the brand, type of mouth rinse, and duration of exposure. The natural mouthrinse was a safe option to prevent accelerated degradation, thus helping to maintain effective therapeutic forces in orthodontic treatments. These findings emphasize the importance of selecting the appropriate chain brand and mouthrinse, as well as considering the frequency of replacement, to optimize outcomes in orthodontic treatment.

Clinical significance: The strength loss of elastomeric chains depends on the brand, the type of mouthwash used, and the duration of exposure; orthodontists should consider these factors when planning treatments. How to cite this article: Sarzosa-Montenegro JL, Arriola-Guillén LE, Rodríguez-Cárdenas YA. Effects of Natural Mouthwash on the Force Degradation of Orthodontic Elastomeric Chains: An In Vitro Experimental Study. J Contemp Dent Pract 2025;26(11):1035-1040.

Aim: This study aims to evaluate the effectiveness of hyaluronic acid (HA) and mint-flavored toothpaste in the recovery from persistent sensory loss.

Materials and methods: A pilot study of 16 adult patients suffering from anosmia or severe hypoanosmia in Baghdad was selected purposively from a larger sample of 135, examined using the Modified Connecticut Chemosensory Clinical Research Center ("modified CCCRC") test between October 2023 and January 2024 and then re-examined 3 weeks later after twice-daily use of the toothpaste, using the same repeatable, objective method, the modified CCCRC test.

Results: The majority of participants were within the age-group of >35 years at 75%, and 56% were males. There was a significant difference between the median composite scores of thresholds and identification of the smell beside the taste score before and after using the toothpaste (p < 0.001, 0.023), respectively.

Conclusion: Smell and taste scores increase after weeks of daily twice using the hyaluronic toothpaste.

Clinical significance: The combination of HA and mint odor in the same product was effective in promoting the recovery of the sense of smell and improving the quality of life of the study participants. How to cite this article: Abdulrida FM, Hadartie SF, Hobballah AI. The Effect of Hyaluronic acid Toothpaste in Smell and Taste Recovery: A Pilot Study. J Contemp Dent Pract 2025;26(11):1103-1108.