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[Evaluation of the efficiency of the method of biological feedback in complex therapy of patients with hypertonus of the chewing muscles]. [咀嚼肌张力过高患者复合疗法中生物反馈法的效率评估]。
Q4 Medicine Pub Date : 2024-01-01 DOI: 10.17116/stomat202410301135
O I Admakin, A V Glazkova, A M Dybov, D S Petelin, B A Volel

The aim the study. Evaluate the effectiveness of biofeedback therapy in the complex rehabilitation of masticatory muscle hypertonicity in patients with a high level of anxiety.

Material and methods: The study included 40 patients aged 20 to 32 years with complaints of fatigue and discomfort in the area of chewing muscles, teeth compression during the day, nocturnal bruxism, crowding of teeth. Two groups were formed: the study group, whose patients underwent splint therapy in combination with biofeedback therapy trainings; in the control group, patients received treatment with splint therapy without the use of biofeedback therapy. Electromyography of the masticatory muscles at rest and during compression were used to diagnose hypertonicity of the masticatory muscles. To assess the psycho-emotional state, a medical and social questionnaire was conducted using questionnaires: «Health Questionnaire», Beck Depression Inventory, Spielberger-Khanin Anxiety Scale, SF-16 Quality of Life Scale.

Results: A decrease in the level of depression, anxiety was revealed with the stabilization of emotional sensitivity in relation to other people, emotional involvement in everyday life, and an increase in the quality of life. When comparing electromyographic data at rest and during clenching of teeth in patients of the study group the indicators were lower than in the control group.

Conclusions: The effectiveness of biofeedback therapy at the stages of orthodontic treatment using splint therapy was established in the form of a decrease in the activity of masticatory muscles in patients of the study group. In the control group, the index of masticatory muscle activity decreased to a lesser extent. Biofeedback methods have shown a high level of effectiveness in reducing the symptoms of anxiety and depression, improving the quality of life.

研究目的评估生物反馈疗法在高度焦虑患者咀嚼肌张力过高综合康复中的有效性:研究对象包括 40 名主诉咀嚼肌疲劳和不适、白天牙齿受压、夜间磨牙症、牙齿拥挤的 20 至 32 岁患者。研究分为两组:研究组患者在接受夹板治疗的同时接受生物反馈疗法训练;对照组患者在接受夹板治疗的同时不使用生物反馈疗法。通过咀嚼肌静息时和按压时的肌电图诊断咀嚼肌肌张力过高。为了评估心理情绪状态,使用问卷进行了医疗和社会问卷调查:健康问卷"、"贝克抑郁量表"、"斯皮尔伯格-卡宁焦虑量表"、"SF-16 生活质量量表":结果表明,随着对他人情感敏感度的稳定、对日常生活情感的投入以及生活质量的提高,抑郁和焦虑程度有所降低。比较研究组患者在休息时和咬牙时的肌电图数据,其指标均低于对照组:在使用夹板疗法进行正畸治疗的阶段,生物反馈疗法的有效性体现在研究组患者咀嚼肌活动的减少上。在对照组中,咀嚼肌活动指数的下降幅度较小。生物反馈方法在减轻焦虑和抑郁症状、提高生活质量方面显示出高度的有效性。
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引用次数: 0
[Evaluation of the photodynamic effect on the state of microcirculation and oxygenation in periodontal tissues in the treatment of chronic generalized periodontitis]. [光动力对治疗慢性泛发性牙周炎时牙周组织微循环和氧合状态的影响评估]。
Q4 Medicine Pub Date : 2024-01-01 DOI: 10.17116/stomat202410302118
E K Krechina, A V Myagkova, Z U Abdurakhmanova, A V Rassadina, I E Guseva, I V Pogabalo

Objective: Increasing the effectiveness of treatment of chronic generalized periodontitis using PDT based on clinical and functional substantiation of the effects of a photosensitizer.

Materials and methods: A clinical and functional study and treatment of moderate chronic generalized periodontitis was carried out in 62 people (26 men and 36 women) aged from 35 to 55 years without a somatic model with an orthognathic occlusion diagnosed according to ICD-10 - K05.3. Of these, 2 groups were divided depending on the type of treatment: Group 1 (main) - patients with moderate chronic generalized periodontitis - 32 people. (17 men and 15 women, average age of the group - 43.2±2.2 years); Group 2 (control) - patients with moderate chronic generalized periodontitis - 30 people. (14 men and 16 women, average age of the group - 44.0±3.3 years). Complex treatment consisted of sanitation of the mouth, removal of dental plaque and curettage of periodontal pockets in group 1, followed by PDT with Revixan gel using a special wired aligner REVIXAN DENTAL LED (16 r). The clinical condition of the periodontium was assessed using the Greene Vermillion Hygienic Index (OHI-S), the Mühlleman Bleeding Index (SBI) modified by Cowell, and the periodontal index PI. To study the state of microcirculation in the gum tissue, the laser Doppler flowmetry (LDF) method was used using the LAKK-M device (NPP «Lazma», Russia). The state of microcirculation was assessed by the microcirculation index (M), which characterizes the level of tissue blood flow; parameter - «σ», which determines the fluctuation of the erythrocyte flow. According to Wavelet analysis of LDF-grams, the shunt index (SH) of blood flow was determined. In the «LDF + spectrometry» mode, oxygenation in periodontal tissues was studied using optical tissue oximetry (OTO), based on the results of which the perfusion saturation index (Sm) and the specific oxygen consumption index (U, %) were determined.

Results: According to LDF data, after PDT (group 1), normalization of clinical indices and the level of microcirculation in periodontal tissues was established, which was accompanied by an increase in the level of blood flow (M) and its activity (σ), which persisted after 3 and 6 months. after PDT. The perfusion saturation index (Sm) and specific oxygen consumption (U) increased more significantly after PDT, which persisted after 3 and 6 months. In the control group, the dynamics of indicators was less pronounced.

Conclusion: The use of PDT with Revixan gel normalizes the clinical condition of the periodontium, indicators of microhemodynamics and oxygen metabolism.

目的根据光敏剂效果的临床和功能证实,提高利用光导治疗慢性泛发性牙周炎的有效性:根据 ICD-10 - K05.3 诊断,对 62 名年龄在 35 至 55 岁之间、无正颌咬合体模型的患者(26 名男性和 36 名女性)进行了中度慢性泛发性牙周炎的临床和功能研究及治疗。其中,根据治疗类型分为两组:第 1 组(主要)--中度慢性牙周炎患者,共 32 人。(男性 17 人,女性 15 人,平均年龄(43.2±2.2)岁);第 2 组(对照组)--中度慢性全身性牙周炎患者--30 人(男性 14 人,女性 16 人,平均年龄(43.2±2.2)岁)。(男性 14 人,女性 16 人,平均年龄为 44.0±3.3 岁)。第 1 组的综合治疗包括口腔卫生、清除牙菌斑和刮治牙周袋,然后使用特殊的有线对准器 REVIXAN DENTAL LED(16 r),用瑞维善凝胶进行光导治疗。牙周的临床状况由格林-维米伦卫生指数(OHI-S)、考威尔改良的穆勒曼出血指数(SBI)和牙周指数 PI 进行评估。为了研究牙龈组织的微循环状况,使用了激光多普勒血流测量法(LDF),使用的是 LAKK-M 设备(俄罗斯,NPP "Lazma")。微循环状态通过微循环指数(M)进行评估,该指数表征组织血流水平;参数--"σ "确定红细胞流量的波动。根据 LDF 图的小波分析,确定了血流的分流指数(SH)。在 "LDF + 光谱分析 "模式下,使用光学组织血氧仪(OTO)研究了牙周组织的氧合情况,并根据研究结果确定了灌注饱和度指数(Sm)和比氧消耗指数(U,%):根据 LDF 数据,PDT(第 1 组)治疗后,临床指标和牙周组织微循环水平恢复正常,同时血流水平(M)和血流活性(σ)增加,这种情况在 PDT 治疗 3 个月和 6 个月后仍持续存在。灌注饱和度指数(Sm)和比氧消耗量(U)在局部放疗后有更明显的增加,这种情况在 3 个月和 6 个月后依然存在。在对照组中,各项指标的动态变化不太明显:结论:使用 Revixan 凝胶进行光导治疗可使牙周的临床状况、微血流动力学指标和氧代谢恢复正常。
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引用次数: 0
[Analysis of the mechanical properties of a material of temporary structures manufactured by direct method and provisional crowns made by 3D printing]. [一种直接制作临时结构材料与3D打印制作临时冠的力学性能分析]。
Q4 Medicine Pub Date : 2024-01-01 DOI: 10.17116/stomat202410306120
S D Shneider, N S Nurieva, A D Yurasov

The aim of this work is to study the mechanical properties of temporary composite crowns and temporary composite orthopedic structures manufactured by 3D printing.

Materials and methods: For the two studied groups of samples: the original 3D-printed samples and the poured samples from a composite material of a certain shape, 8 samples were made and visually checked for the absence of porosity. The strength and elasticity were measured using the three-point bending method and the hardness was measured using the indentation method.

Results: For both materials, the hardness, flexural strength and flexural elasticity show consistently high values required by GOST 24621-2015 (ISO 868:2003) [Plastics and ebonite] and GOST 4648-2014 (ISO 178:2010) [Plastics]. However, the statistical data on bending are higher for the composite material, with a larger spread of the elastic modulus value, in contrast to the 3D-printed samples.

Conclusion: Both materials are suitable for the manufacture of temporary orthopedic structures. For a more accurate assessment, it is necessary to continue studying the 3D-printed material for cytotoxicity, water absorption, and microstructure.

本研究的目的是研究3D打印制造的临时复合冠和临时复合矫形结构的力学性能。材料和方法:对于两组研究样品:原始3d打印样品和由一定形状的复合材料浇注的样品,制作了8个样品,并目测有无孔隙。采用三点弯曲法测定强度和弹性,采用压痕法测定硬度。结果:两种材料的硬度、抗弯强度和抗弯弹性均符合GOST 24621-2015 (ISO 868:2003)[塑料和胶木]和GOST 4648-2014 (ISO 178:2010)[塑料]所要求的高值。然而,与3d打印样品相比,复合材料的弯曲统计数据更高,弹性模量值的分布更大。结论:两种材料均适用于临时矫形结构的制作。为了更准确的评估,有必要继续研究3d打印材料的细胞毒性,吸水率和微观结构。
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引用次数: 0
[Dental caries among 15-year-old adolescents in Arctic Russia: a systematic review and meta-analysis]. [俄罗斯北极地区15岁青少年龋齿:系统回顾和荟萃分析]。
Q4 Medicine Pub Date : 2024-01-01 DOI: 10.17116/stomat202410306166
M A Gorbatova, P A Pochinkova, E A Mitkina, A A Simakova, A M Grjibovski

Objective: The aim of the study is to perform a systematic search, qualitative synthesis, and a meta-analysis of scientific publications on the prevalence and experience of dental caries among 15-year-old adolescents in the Arctic zone of the Russian Federation.

Materials and methods: A systematic review based on PRISMA guidelines. The review includes sources that describe the prevalence and intensity of caries in 15-year-old adolescents within the Arctic zone of the Russian Federation. Publications from 1998-2023 in English and Russian were searched for using the PubMed and eLIBRARY platforms. In total, 208 publications identified, but only 4 were included in meta-analysis.

Results: The total number of adolescents in the studies included in the review was 1567 with a significant proportion being residents of the Arkhangelsk region. The weighted prevalence of caries was 87.9% (95% CI: 83.7-91.7%). The statistically significant increase was registered only in the city of Norilsk. In Arkhangelsk, the increase in the prevalence of caries was accompanied by a decrease in the activity of the carious process, which was due to a significant decrease in the K component in the structure of the DMFT index.

Conclusion: The review provides the evidence on a high prevalence of caries among 15-year-old adolescents in Arctic Russia. Further research of the dental status of adolescents is warranted as well as the development of effective preventive measures on individual and population levels.

目的:本研究的目的是对俄罗斯联邦北极地区15岁青少年龋齿患病率和经历的科学出版物进行系统搜索、定性综合和荟萃分析。材料和方法:基于PRISMA指南的系统综述。该审查包括描述俄罗斯联邦北极地区15岁青少年龋齿患病率和强度的资料来源。使用PubMed和eLIBRARY平台检索1998-2023年的英文和俄文出版物。总共确定了208篇出版物,但只有4篇被纳入元分析。结果:纳入研究的青少年总数为1567人,其中很大一部分是阿尔汉格尔斯克地区的居民。加权龋患病率为87.9% (95% CI: 83.7 ~ 91.7%)。统计上有显著增长的只有诺里尔斯克市。在阿尔汉格尔斯克,龋齿患病率的增加伴随着龋齿过程活动的减少,这是由于DMFT指数结构中K成分的显著减少。结论:本综述提供了俄罗斯北极地区15岁青少年龋齿高发的证据。有必要进一步研究青少年的牙齿状况,并在个人和人口层面制定有效的预防措施。
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引用次数: 0
[Mechanical properties of photopolymerisable compositions for the creation of bone and dental tissue equivalents]. [用于制造骨和牙组织等效物的光聚合组合物的机械特性]。
Q4 Medicine Pub Date : 2024-01-01 DOI: 10.17116/stomat20241030625
I S Rudik, A V Mironov, V S Kuznetsova, A V Vasilyev

The aim of the study: Was to elaborate and assess biocompatible compositions based on oligocarbonate methacrylate filled with hydroxyapatite.

Materials and methods: The manufacturing methods of the compositions are considered, and their polymerization ability, strength and elastic properties are evaluated.

Results: The highest values of hardness and elasticity were found in the composition containing 0.50% by weight of diphenyl (2.4,6-trimethylbenzoate)phosphine oxide and 10% by weight of hydroxyapatite. Its compressive strength was comparable to bone tissue and dental cements.

Conclusion: The described composition can be used as a model system for assessing the physical and mechanical properties of materials used to fill defects in dental tissue and bone.

本研究的目的是制备和评价以羟基磷灰石填充的甲基丙烯酸低聚碳酸盐为基础的生物相容性组合物。材料和方法:研究了复合材料的制备方法,并对其聚合能力、强度和弹性性能进行了评价。结果:二苯基(2.4,6-三甲基苯甲酸酯)氧化膦含量为0.50%(重量计)和羟基磷灰石含量为10%(重量计)时硬度和弹性最高。其抗压强度与骨组织和牙水泥相当。结论:所述组合物可作为评估牙组织和骨缺损填充材料物理力学性能的模型系统。
{"title":"[Mechanical properties of photopolymerisable compositions for the creation of bone and dental tissue equivalents].","authors":"I S Rudik, A V Mironov, V S Kuznetsova, A V Vasilyev","doi":"10.17116/stomat20241030625","DOIUrl":"https://doi.org/10.17116/stomat20241030625","url":null,"abstract":"<p><strong>The aim of the study: </strong>Was to elaborate and assess biocompatible compositions based on oligocarbonate methacrylate filled with hydroxyapatite.</p><p><strong>Materials and methods: </strong>The manufacturing methods of the compositions are considered, and their polymerization ability, strength and elastic properties are evaluated.</p><p><strong>Results: </strong>The highest values of hardness and elasticity were found in the composition containing 0.50% by weight of diphenyl (2.4,6-trimethylbenzoate)phosphine oxide and 10% by weight of hydroxyapatite. Its compressive strength was comparable to bone tissue and dental cements.</p><p><strong>Conclusion: </strong>The described composition can be used as a model system for assessing the physical and mechanical properties of materials used to fill defects in dental tissue and bone.</p>","PeriodicalId":35887,"journal":{"name":"Stomatologiya","volume":"103 6. Vyp. 2","pages":"5-9"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143012967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[The results of increasing the thickness of soft tissues after using collagen matrices and connective tissue grafts]. [胶原基质和结缔组织移植后软组织增厚的结果]。
Q4 Medicine Pub Date : 2024-01-01 DOI: 10.17116/stomat202410306229
A D Posessor, V A Badalyan, A V Vasilyev

The study aims: To evaluate and compare the growth of gingiva around dental implants following the use of collagen matrices and connective tissue grafts (CTG).

Materials and methods: The study included 80 study participants, who were divided into four groups based on the type of material used to enhance gingival thickness. Two groups utilized collagen matrices, Fibro-Gide and FibroMatrix as materials, while the other two groups utilized CTG obtained from the hard palate or tubercle area of the maxilla as controls. Measurements of gum tissue thickness were obtained before surgery and three- and six-months following surgery using three different methods: mucosa piercing with a spreader and ruler, digital impression, and comparison of cone-beam computed tomography (CBCT) scans and digital impressions.

Results: At six-months examination after the use of grafts from the palate and tubercle, there was a significantly greater increase in gum tissue thickness compared to the use of collagen matrices. The increase was 1.6±0.3 mm and 1.7±0.6 mm for palatal and tubercle grafts, correspondingly, compared to 1.3±0.4 mm for Fibro-Gide and 0.9±0.5 mm for FibroMatrix.

Conclusion: To increase the thickness of soft tissue it is recommended to use CTG from the tubercle or palate. If there is a lack of available donor areas, collagen matrices may be used as a substitute.

研究目的:评价和比较胶原基质和结缔组织移植(CTG)对种植体周围牙龈生长的影响。材料和方法:该研究包括80名研究参与者,他们根据用于增加牙龈厚度的材料类型分为四组。两组以胶原基质、fiber - gide和FibroMatrix为材料,另两组以上颌硬腭或结节区获得的CTG为对照。使用三种不同的方法在手术前和手术后3个月和6个月测量牙龈组织厚度:用扩张器和尺子穿刺粘膜,数字印模,锥形束计算机断层扫描(CBCT)扫描和数字印模的比较。结果:在使用腭和结节移植物后6个月的检查中,与使用胶原基质相比,牙龈组织厚度明显增加。腭和结核移植物分别增加1.6±0.3 mm和1.7±0.6 mm,而纤维基体为1.3±0.4 mm,纤维基质为0.9±0.5 mm。结论:为增加软组织厚度,建议从结节或上颚取CTG。如果缺乏可用的供体区域,可以使用胶原基质作为替代品。
{"title":"[The results of increasing the thickness of soft tissues after using collagen matrices and connective tissue grafts].","authors":"A D Posessor, V A Badalyan, A V Vasilyev","doi":"10.17116/stomat202410306229","DOIUrl":"https://doi.org/10.17116/stomat202410306229","url":null,"abstract":"<p><strong>The study aims: </strong>To evaluate and compare the growth of gingiva around dental implants following the use of collagen matrices and connective tissue grafts (CTG).</p><p><strong>Materials and methods: </strong>The study included 80 study participants, who were divided into four groups based on the type of material used to enhance gingival thickness. Two groups utilized collagen matrices, Fibro-Gide and FibroMatrix as materials, while the other two groups utilized CTG obtained from the hard palate or tubercle area of the maxilla as controls. Measurements of gum tissue thickness were obtained before surgery and three- and six-months following surgery using three different methods: mucosa piercing with a spreader and ruler, digital impression, and comparison of cone-beam computed tomography (CBCT) scans and digital impressions.</p><p><strong>Results: </strong>At six-months examination after the use of grafts from the palate and tubercle, there was a significantly greater increase in gum tissue thickness compared to the use of collagen matrices. The increase was 1.6±0.3 mm and 1.7±0.6 mm for palatal and tubercle grafts, correspondingly, compared to 1.3±0.4 mm for Fibro-Gide and 0.9±0.5 mm for FibroMatrix.</p><p><strong>Conclusion: </strong>To increase the thickness of soft tissue it is recommended to use CTG from the tubercle or palate. If there is a lack of available donor areas, collagen matrices may be used as a substitute.</p>","PeriodicalId":35887,"journal":{"name":"Stomatologiya","volume":"103 6. Vyp. 2","pages":"29-32"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143013144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Dynamics of mandibular density during therapy with zolendronic acid]. [唑伦膦酸治疗期间下颌骨密度的动态变化]。
Q4 Medicine Pub Date : 2024-01-01 DOI: 10.17116/stomat202410304133
N S Nurieva, I G Shelegova, V A Fanakin

The aim of the study: Was to investigate the dynamics of mandibular density in cancer patients during therapy with zolendronic acid.

Materials and methods: The study comprised 14 patients who received zolendronic acid at a dosage of 4 mg once every 28 days for bone metastases. In all 14 patients, measurements of mandibular density values on CT scans were performed over time.

Results: Using multiple linear regression analysis, a model was developed to predict the effect of the number of zolendronic acid injections «X1» on the dynamics of mandibular density «Y». The resulting formula for predicting mandibular density is Y = 5.9 X1 + 49 HU.

Conclusion: The model has limitations due to the study design but still can be used by oncologists and dentists to assess mandibular density in patients taking zolendronic acid.

研究目的旨在研究癌症患者在使用唑伦膦酸治疗期间下颌骨密度的动态变化:研究对象包括14名接受唑仑膦酸治疗的骨转移患者,剂量为每28天一次,每次4毫克。在所有 14 名患者中,随时间推移对 CT 扫描的下颌骨密度值进行了测量:通过多元线性回归分析,建立了一个模型来预测唑伦膦酸注射次数 "X1 "对下颌骨密度动态 "Y "的影响。由此得出的下颌骨密度预测公式为 Y = 5.9 X1 + 49 HU:由于研究设计的原因,该模型存在一定的局限性,但仍可用于肿瘤学家和牙科医生评估服用唑伦膦酸患者的下颌骨密度。
{"title":"[Dynamics of mandibular density during therapy with zolendronic acid].","authors":"N S Nurieva, I G Shelegova, V A Fanakin","doi":"10.17116/stomat202410304133","DOIUrl":"https://doi.org/10.17116/stomat202410304133","url":null,"abstract":"<p><strong>The aim of the study: </strong>Was to investigate the dynamics of mandibular density in cancer patients during therapy with zolendronic acid.</p><p><strong>Materials and methods: </strong>The study comprised 14 patients who received zolendronic acid at a dosage of 4 mg once every 28 days for bone metastases. In all 14 patients, measurements of mandibular density values on CT scans were performed over time.</p><p><strong>Results: </strong>Using multiple linear regression analysis, a model was developed to predict the effect of the number of zolendronic acid injections «X<sub>1</sub>» on the dynamics of mandibular density «Y». The resulting formula for predicting mandibular density is Y = 5.9 X<sub>1</sub> + 49 HU.</p><p><strong>Conclusion: </strong>The model has limitations due to the study design but still can be used by oncologists and dentists to assess mandibular density in patients taking zolendronic acid.</p>","PeriodicalId":35887,"journal":{"name":"Stomatologiya","volume":"103 4","pages":"33-36"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142018971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Distinctions in molecular composition of the dental biofilm in a dependence of method of exo/endogeneous caries prevention and cariogenic condition of a patient]. [牙齿生物膜分子组成的差异取决于外源性/内源性防龋方法和患者的致龋情况]。
Q4 Medicine Pub Date : 2024-01-01 DOI: 10.17116/stomat20241030515
P V Seredin, Yu A Ippolitov, Y A Peshkov, D L Goloshchapov, I Yu Ippolitov, O G Avraamova

Objective: Comparative study of changes in the secondary structure of dental biofilm proteins in people with cariesogenic and cariesoprotective status using synchrotron IR microspectroscopy.

Materials and methods: Dental biofilm samples from 50 patients without caries (group 1) and with carious lesions of tooth enamel (group 2) were studied. The molecular composition of biofilms was studied using IR microspectroscopy. Changes in the secondary structure of dental biofilm proteins were evaluated based on deconvolution of Amide I or Amide II amide bands. using the analysis of variance. Patients of both groups took tablets containing a mineral complex with calcium glycerophosphate.

Results: Based on the deconvolution of the IR spectral profile of the Amide I and Amide II bands, the changes occurring in the secondary structure of dental biofilm proteins have been studied. Using a large set of spectra, it was shown that the prediction of the secondary structure of the biofilm protein network is influenced by both the cariesogenic situation in the oral cavity (with initial carious lesions of the enamel) and the fact that patients use a modulator - calcium glycerophosphate (a tableted mineral complex with calcium glycerophosphate). Significant intra-group and intergroup differences in the secondary structure of dental biofilm proteins were established for patients in normal and carisogenic situations in the mouth, including after the use of a tableted mineral complex with calcium glycerophosphate. This allowed us to give a mathematical assessment of shifts in the secondary structure of proteins depending on the activity of caries and external modulation.

Conclusion: The results obtained can form the basis of a technique for spectroscopic diagnosis of changes (shifts) in the oral microbiome leading to the development of the carious process, as well as become the basis for choosing the optimal therapeutic ways to treat enamel caries, including through preventive measures aimed at restoring the microflora of the patient's oral cavity.

摘要利用同步辐射红外显微光谱技术,比较研究致龋和防龋人群牙齿生物膜蛋白质二级结构的变化:研究了50名无龋患者(第1组)和牙釉质龋损患者(第2组)的牙齿生物膜样本。采用红外显微光谱法研究了生物膜的分子组成。根据酰胺 I 或酰胺 II 酰胺带的解卷积,利用方差分析评估了牙科生物膜蛋白质二级结构的变化。两组患者均服用含有甘油磷酸钙矿物质复合物的药片:根据对酰胺 I 和酰胺 II 带的红外光谱剖面的解卷积,研究了牙科生物膜蛋白质二级结构发生的变化。通过对大量光谱的研究表明,生物膜蛋白质网络二级结构的预测受到口腔致龋情况(珐琅质的初始龋损)和患者使用调制剂--甘油磷酸钙(含甘油磷酸钙的片状矿物质复合物)的影响。在口腔正常和龋坏情况下,包括在使用含甘油磷酸钙的片状矿物质复合物后,患者口腔内牙齿生物膜蛋白质的二级结构存在明显的组内和组间差异。这使我们能够对蛋白质二级结构的变化进行数学评估,这种变化取决于龋齿的活动和外部调节:所获得的结果可以作为口腔微生物群变化(转变)光谱诊断技术的基础,导致龋坏过程的发展,并成为选择最佳治疗方法治疗釉质龋的基础,包括通过旨在恢复患者口腔微生物群的预防措施。
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引用次数: 0
[Improving the effectiveness of local anesthesia in patients with arterial hypertension in the provision of emergency dental care]. [提高牙科急诊中动脉高血压患者局部麻醉的效果]。
Q4 Medicine Pub Date : 2024-01-01 DOI: 10.17116/stomat202410302132
E N Anisimova, N Yu Anisimova, I V Orekhova, Yu V Sedyakina

The aim of the study: Was to evaluate the use of Ketorol Express as a preventive analgesia to increase the effectiveness of local anesthesia in providing emergency dental care to patients with arterial hypertension.

Materials and methods: The study was conducted on the basis of the state autonomous healthcare institution of the Moscow region «Royal Dental Clinic» with the participation of 83 people. The patients were divided into two groups. In group 1, Ketorol Express was prescribed as a preventive analgesia in a dosage of 20 mg before local anesthesia. Patients of group 2 underwent dental interventions without the use of preventive analgesia. A 3% solution of mepivacaine was used as a local analgesic solution. For a subjective assessment of the effectiveness of anesthesia, use a visual analog scale. All patients had their blood pressure and heart rate measured before and after the interventions and hemodynamic parameters were continuously monitored during emergency dental care.

Results: In group 1, the effectiveness of combined anesthesia with the infiltration method of local anesthetic administration was 93±1.17%, according to the patient, 94±1.47%, according to the doctor, with the conductive method of anesthesia at the mandibular orifice - according to the patient it was 91±1.01%, according to the doctor 92± 1.36%. In group 2, when providing emergency dental care with the infiltration method of administration of 3% mepivacaine the anesthesia was effective in 80±1.97% of cases according to the patient and in 80±1.17% of cases according to the doctor, with the conductive method of anesthesia at the mandibular orifice, the effectiveness of anesthesia according to the patient was 82±1.11%, according to the doctor 85±1.23%.

Conclusion: The results of the study demonstrated a statistically significant increase in the effectiveness of local anesthesia performed with a 3% solution of mepivacaine in patients with arterial hypertension due to the use of preventive analgesia with Ketorol Express at a dosage of 20 mg (2 tablets of 10 mg) in emergency dental care with registration and analysis of changes in hemodynamic parameters.

研究目的旨在评估在为动脉高血压患者提供牙科急诊护理时,使用 Ketorol Express 作为预防性镇痛剂以提高局部麻醉效果的情况:研究在莫斯科州国家自治医疗机构 "皇家牙科诊所 "的基础上进行,共有 83 人参与。患者被分为两组。第 1 组患者在局部麻醉前使用 20 毫克的 Ketorol Express 作为预防性镇痛剂。第 2 组患者在不使用预防性镇痛剂的情况下接受牙科治疗。使用 3% 的甲哌卡因溶液作为局部镇痛溶液。对于麻醉效果的主观评估,使用视觉模拟量表。所有患者在干预前后都测量了血压和心率,在牙科急诊护理期间持续监测血液动力学参数:在第一组中,采用浸润法局部麻醉的联合麻醉有效率患者为(93±1.17)%,医生为(94±1.47)%;采用下颌口传导法麻醉的有效率患者为(91±1.01)%,医生为(92±1.36)%。在第2组中,在使用3%甲哌卡因浸润法进行牙科急诊护理时,患者的麻醉有效率为80±1.97%,医生的麻醉有效率为80±1.17%;在使用下颌口传导麻醉法时,患者的麻醉有效率为82±1.11%,医生的麻醉有效率为85±1.23%:研究结果表明,在牙科急诊护理中使用剂量为20毫克(2片10毫克)的Ketorol Express进行预防性镇痛,并对血液动力学参数的变化进行登记和分析,动脉高血压患者使用3%甲哌卡因溶液进行局部麻醉的有效性在统计学上有显著提高。
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引用次数: 0
[Pulp revascularization procedure for external inflammatory dental root resorption treatment]. [牙髓血管再通术治疗外源性炎症性牙根吸收]。
Q4 Medicine Pub Date : 2024-01-01 DOI: 10.17116/stomat202410302180
M V Korolenkova, L Yu Kharkova, M S Rakhmanova

The aim of the study: To assess the effectiveness of pulp revascularization procedure in children with external inflammatory root resorption (EIRR) after constant teeth injury.

Materials and methos: The study comprised 17 children aged 6-10 years diagnosed with EIRR as a long-term complication of dental trauma in 19 teeth. EIRR was diagnosed with periapical radiographs and CBCT was performed to further assess the pathology extension. Pulp revascularization was carried out in all 19 teeth.

Results: There was no resorption progression in all cases. EIRR areas were substituted by bone. In 10 from 19 teeth with early stages of root development bone or cement-like tissue ingrowth into the root canal was observed radiologically. In cases of severe EIRR this ingrowth may partially compensate for lost tissues which is confirmed by a high percentage (94.7%) of functional teeth during mean follow up time of 38±10 months.

Conclusion: Pulp revascularization is an effective method for retaining teeth with EIRR for a relatively long period of time and allows maintaining alveolar bone volume both due to functional tooth preservation and healing of bone lesions in periapical and resorption areas.

研究目的材料和方法:该研究包括17名6-10岁儿童,他们被诊断为19颗牙齿的外部炎症性牙根吸收(ERR),这是牙齿外伤的长期并发症。通过根尖周X光片诊断出ERR,并进行CBCT进一步评估病理延伸。对所有 19 颗牙齿进行了牙髓血管重建:结果:所有病例均无吸收进展。ERR区域被骨替代。在 19 颗牙根发育早期阶段的牙齿中,有 10 颗牙齿的根管中出现了骨质或类似水泥的组织生长。在严重ERIRR的病例中,这种组织的长入可以部分弥补失去的组织,在平均38±10个月的随访时间内,高比例(94.7%)的功能牙证实了这一点:结论:牙髓再血管化是一种有效的方法,可以在相对较长的时间内保留有 EIRR 的牙齿,并且由于功能性牙齿的保留以及根尖周和吸收区骨质病变的愈合,可以保持牙槽骨量。
{"title":"[Pulp revascularization procedure for external inflammatory dental root resorption treatment].","authors":"M V Korolenkova, L Yu Kharkova, M S Rakhmanova","doi":"10.17116/stomat202410302180","DOIUrl":"https://doi.org/10.17116/stomat202410302180","url":null,"abstract":"<p><strong>The aim of the study: </strong>To assess the effectiveness of pulp revascularization procedure in children with external inflammatory root resorption (EIRR) after constant teeth injury.</p><p><strong>Materials and methos: </strong>The study comprised 17 children aged 6-10 years diagnosed with EIRR as a long-term complication of dental trauma in 19 teeth. EIRR was diagnosed with periapical radiographs and CBCT was performed to further assess the pathology extension. Pulp revascularization was carried out in all 19 teeth.</p><p><strong>Results: </strong>There was no resorption progression in all cases. EIRR areas were substituted by bone. In 10 from 19 teeth with early stages of root development bone or cement-like tissue ingrowth into the root canal was observed radiologically. In cases of severe EIRR this ingrowth may partially compensate for lost tissues which is confirmed by a high percentage (94.7%) of functional teeth during mean follow up time of 38±10 months.</p><p><strong>Conclusion: </strong>Pulp revascularization is an effective method for retaining teeth with EIRR for a relatively long period of time and allows maintaining alveolar bone volume both due to functional tooth preservation and healing of bone lesions in periapical and resorption areas.</p>","PeriodicalId":35887,"journal":{"name":"Stomatologiya","volume":"103 2","pages":"80-85"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140915881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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Stomatologiya
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