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[Application of surface electromyography in patients with functional disorders of the masticatory muscles]. 面肌电图在咀嚼肌功能障碍患者中的应用
Q4 Medicine Pub Date : 2025-01-01 DOI: 10.17116/stomat202510404183
F F Losev, P N Geletin, A I Nikolaev, M S Kotik, S V Tekucheva, P V Loputneva

Objective: To compare the results of surface electromyography in patients with functional disorders of the masticatory muscles at all stages of complex therapy and to demonstrate the need for the introduction of a generally accepted comprehensive approach to the examination and treatment of patients with this pathology.

Material and methods: EMG studies were conducted in 127 patients of both sexes aged 35 to 54 years, who were divided into 2 groups. The first (control group) consisted of 20 patients without signs of functional disorders in the masticatory muscles. The second (main) group included 107 patients of both sexes with functional disorders in the masticatory muscles. The examination was carried out using a portable electromyograph "Synapsis" (Neurotech), adapted for dental purposes.

Results: The application of surface electromyography in patients with functional disorders of the masticatory muscles revealed statistically significant differences in the values of the compared indices. EMG allowed for a visual assessment of the work of the masticatory musculature based on the results of qualitative and quantitative indicators of the bioelectrical activity of the masticatory muscles.

Conclusion: Performing surface EMG at all stages of rehabilitation is of undeniable value as the most accessible and informative method for diagnosing neuromuscular disorders in patients with increased tooth wear and masticatory muscle dysfunction, which improves the quality of orthopedic treatment.

目的:比较咀嚼肌功能障碍患者在复杂治疗的各个阶段的表面肌电图结果,并证明需要引入一种普遍接受的综合方法来检查和治疗具有这种病理的患者。材料与方法:对127例35 ~ 54岁男女患者进行肌电图研究,分为两组。第一组(对照组)包括20名无咀嚼肌功能障碍症状的患者。第二组(主要)包括107例有咀嚼肌功能障碍的男女患者。检查使用便携式肌电描记仪“Synapsis”(Neurotech)进行,适用于牙科用途。结果:表面肌电图在咀嚼肌功能障碍患者中的应用,比较指标的数值差异有统计学意义。肌电图可以根据咀嚼肌肉生物电活动的定性和定量指标的结果,对咀嚼肌肉的工作进行视觉评估。结论:在康复的各个阶段进行表面肌电图是诊断牙齿磨损加重、咀嚼肌功能障碍患者神经肌肉疾病最方便、信息量最大的方法,具有不可否认的价值,提高了骨科治疗的质量。
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引用次数: 0
[Melanoma of the maxillary sinus mucosa]. [上颌窦粘膜黑色素瘤]。
Q4 Medicine Pub Date : 2025-01-01 DOI: 10.17116/stomat202510402182
M Yu Beteeva, I A Zaderenko, K S Mkrtchyan, A A Muraev

The article presents an overview of the intermediate results of treatment for maxillary sinus melanoma in a 66-year-old patient. The importance of timely diagnosis and active surgical tactics for achieving the best survival results up to 5 years is noted. After further examination, the diagnosis was confirmed, the patient underwent genomic sequencing of the tumor tissue biopsy, which revealed a BRAF mutation. In this regard, adjuvant therapy was prescribed according to the dabrafenib+trametinib regimen. It was noted that this rare pathology requires careful study, monitoring of clinical outcomes and features of surgical tactics, considering the multifocal nature of the tumor and its high aggressiveness in comparison with the cutaneous form. In the future, the possibility of surgical intervention is discussed, extensive resection is considered, the expected volume, which can reach the removal of both soft tissue and bone structures up to resection of a part of the lower wall of the orbit.

本文概述了上颌窦黑色素瘤治疗的中间结果在一个66岁的病人。及时诊断和积极的手术策略对于达到5年的最佳生存结果的重要性被注意到。经进一步检查确诊后,患者行肿瘤组织活检基因组测序,发现BRAF突变。在这方面,根据dabrafenib+trametinib方案进行辅助治疗。值得注意的是,这种罕见的病理需要仔细研究,监测临床结果和手术策略的特点,考虑到肿瘤的多灶性和与皮肤形式相比的高侵袭性。在未来,讨论手术干预的可能性,考虑广泛切除,预期的体积,可以达到软组织和骨结构的切除,直到切除部分眶下壁。
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引用次数: 0
[3D-morphometric analysis of stomatognatic system in patients with class II malocclusion according to CBCT]. [CBCT对ⅱ类错颌患者口颌系统的三维形态分析]。
Q4 Medicine Pub Date : 2025-01-01 DOI: 10.17116/stomat202510405137
N Yu Oborotistov, Yu A Gioeva, Y I Afanaseva, E I Karamisheva

Objective: To conduct a comparative analysis of the sizes and positions of maxillofacial structures in patients with distal occlusion (gnathic and dentoalveolar forms) using a new 3D analysis.

Material and methods: The object of the study were 132 patients with the gnathic form of distal occlusion of both sexes aged 18 to 45 years, including 79 women and 53 men. All patients underwent cone-beam computed tomography of the skull using KavoExam equipment with subsequent automated 3D cephalometric calculation in ViSurgery 3Dstudio software. We assessed 3D parameters on the right and left sides, as well as their 2D projection onto the midsagittal plane constructed using landmarks - cephalometric points S, N, A. Linear and angular parameters of the position and relative position of the jaws were determined using the values of Witts, SNA, SNB, ANB, B-A-Pg, S-N-Pg, ML-R/NSL, ML-L/NSL, NL-R/ML-R, NL-L/ML-L, ML/OcP, GoR - PNS, GoL-PNS and their projection onto the midsagittal plane. The angular parameters determining the direction of facial skull growth on the right and left corresponded to N-S-ArR, N-S-ArL, ArR-GoR-Me, ArL-GoL-Me, CoR-GoR-Me, CoL-GoL-Me. The angles and sizes of the position of the upper (∠SNA, PNS-A'), lower (∠SNB, Go-Pg) jaw relative to the anterior base of the skull, and the intermaxillary angle (∠ANB) were determined.

Results: In both males and females, the gnathic form of distal occlusion was caused by lower retro-, micrognathia with prevalence of the horizontal type of growth of the facial part of the skull. For males and females with the dentoalveolar form of distal occlusion, the vertical type of growth of the facial part of the skull was characteristic; at the same time, lower micrognathia was noted, as in individuals with the gnathic form of distal occlusion.

Conclusion: The proposed cephalometric analysis in the ViSurgery software allows for an automated detailed study of the cranial-maxillary relationships in three-dimensional space and a complete picture of the severity and determinacy of the existing anomaly.

目的:采用一种新的三维分析方法对远端牙颌型和牙槽型颌面结构的大小和位置进行比较分析。材料与方法:研究对象为132例18 ~ 45岁的男女颌形远端咬合患者,其中女性79例,男性53例。所有患者均使用KavoExam设备对颅骨进行锥束计算机断层扫描,随后在ViSurgery 3Dstudio软件中进行自动3D头颅测量计算。利用Witts、SNA、SNB、ANB、B-A-Pg、S-N- pg、ML- r /NSL、ML- r /ML- r、NL-L/ML- l、ML/OcP、GoR -PNS、golg -PNS的值及其在矢状面上的投影来确定颌骨位置和相对位置的线性和角度参数。左右决定面部颅骨生长方向的角度参数分别为N-S-ArR、N-S-ArL、arr - go - me、arl - go - me、cor - go - me、col - go - me。测定上颌骨(∠SNA, PNS-A’)、下颌骨(∠SNB, Go-Pg)相对于颅骨前底位置的角度和大小,以及上颌骨间角(∠ANB)。结果:在男性和女性中,下颌远端咬合是由下颌后缩、小颌引起的,颅骨面部的水平型生长普遍存在。对于远端牙槽状咬合的男性和女性,颅骨面部的垂直型生长具有特征;同时,下小颌畸形也被注意到,就像在远端咬合的个体中一样。结论:在ViSurgery软件中提出的头颅测量分析允许在三维空间中自动详细研究颅颌关系,并全面了解现有异常的严重性和确定性。
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引用次数: 0
[Evaluation of the effectiveness of adaptation of children with autism spectrum disorders to dental care]. 自闭症谱系障碍儿童对牙科护理的适应效果评价。
Q4 Medicine Pub Date : 2025-01-01 DOI: 10.17116/stomat202510405143
E A Nagoeva, A M Kardangusheva

Objective: The aim the studi is to evaluation of the effectiveness of the method of adaptation of children with autism spectrum disorders to a dental appointment using augmented reality technology.

Materials and methods: 76 children with autism spectrum disorders aged 3 to 16 years were examined and divided into 2 comparable groups. In group 1, standard adaptation of children to a dentist's appointment was carried out, in group 2, a method of adaptation of children developed using augmented reality (AR) technology was additionally used. To determine the degree of anxiety of children with autism, the Frankl behavioral scale was used before and after the application of the developed adaptation method.

Results: In the second group, more children with autism spectrum disorders adapted to dental visits. Specifically, the percentage of children displaying absolutely negative behavior dropped significantly (from 26.3% to 2.6%, p<0.05), as did those with negative behavior (from 23.7% to 2.6%, p<0.05). Conversely, the number of children exhibiting absolutely positive behavior increased (from 26.3% to 50%, p<0.05). Overall, the percentage of children with negative or absolutely negative behavior decreased dramatically, from 50% to 5.2% (p<0.05). These findings demonstrate the effectiveness of the proposed methodology and support its recommendation for practical use.

Conclusion: The use of the technique for adapting children with ASD to a dental appointment, developed using PAP and AR technology, helps to reduce the manifestation of undesirable behavior in children with ASD and can be used to prepare a child for a dental appointment and dental manipulations.

目的:本研究的目的是评估使用增强现实技术适应自闭症谱系障碍儿童牙科预约的方法的有效性。材料与方法:将76例3 ~ 16岁自闭症谱系障碍患儿分为两组。在第1组中,儿童对牙医预约进行标准适应,在第2组中,使用增强现实(AR)技术开发的儿童适应方法。为了确定自闭症儿童的焦虑程度,在应用发达适应法前后分别使用Frankl行为量表。结果:在第二组中,更多的自闭症谱系障碍儿童适应了牙科就诊。具体而言,表现出绝对负面行为的儿童比例显著下降(从26.3%降至2.6%)。结论:使用PAP和AR技术开发的适应ASD儿童牙科预约的技术有助于减少ASD儿童不良行为的表现,并可用于为儿童牙科预约和牙科操作做准备。
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引用次数: 0
[Molar-incisor hypomineralization and its association with dental caries among adolescents in the European North of Russia]. [在俄罗斯欧洲北部的青少年中,磨牙-切牙低矿化及其与龋齿的关系]。
Q4 Medicine Pub Date : 2025-01-01 DOI: 10.17116/stomat202510405148
M A Gorbatova, E A Mitkina, T N Yushmanova, A A Simakova, A M Grjibovski

Objective: The aim of the study to assess the prevalence of MIH among adolescents in the Nenets Autonomous Okrug (NAO), the Komi Republic (KR), and the Murmansk region (MR), as well as associations between MIH and caries experience.

Material and methods: This cross-sectional study included 250, 189, and 126 adolescents aged 15-17 years, residing in NAO (Naryan-Mar and 3 rural settlements), KR (Syktyvkar), and MR (Murmansk), respectively. The Weerheijm criteria were used to diagnose MIH. Caries experience was assessed using the WHO methodology (2013) with the calculation of the DMFT index and its components. All indicators were calculated with 95% confidence intervals (CIs). Differences in categorical and numeric variables were analyzed using non-parametric Pearson's chi-squared and Mann-Whitney tests, respectively.

Results: The prevalence of MIH in the studied regions was 5.20% in NAO, 3.70% in KR, and 4.76% in MR. The CPI index was significantly higher in adolescents with MRC of 7.62 than in those with normal enamel structure of 5.48 due to a greater number of carious teeth of 2.23 and 1.13, respectively. When assessing the prevalence of MIH by gender, it was determined that in the of Komi Republic, the frequency of MIH among girls was significantly higher - 6.00% versus 1.12% among boys, while statistical significance was not achieved.

Conclusions: The prevalence of MIH among adolescents in the studied areas of the Russian North is significantly lower than in most other countries. However, adolescents with MIH exhibit a significantly higher intensity of carious lesions, warranting the development of preventive measures targeting MIH.

目的:本研究旨在评估涅涅茨自治区(NAO)、科米共和国(KR)和摩尔曼斯克地区(MR)青少年MIH的患病率,以及MIH与龋齿经历之间的关系。材料和方法:这项横断面研究包括250、189和126名15-17岁的青少年,分别居住在NAO (Naryan-Mar和3个农村定居点)、KR (Syktyvkar)和MR(摩尔曼斯克)。采用Weerheijm标准诊断MIH。使用世卫组织方法(2013年)评估龋病经验,计算DMFT指数及其组成部分。所有指标均以95%置信区间(ci)计算。分类变量和数值变量的差异分别采用非参数皮尔逊卡方检验和曼-惠特尼检验进行分析。结果:研究区NAO组MIH患病率为5.20%,KR组为3.70%,mr组为4.76%,MRC为7.62的青少年CPI指数明显高于釉质结构正常的青少年(5.48),因其龋齿数较多,分别为2.23和1.13。在按性别评估MIH患病率时,确定在科米共和国,女孩的MIH患病率显著高于男孩,为6.00%,而男孩为1.12%,但未达到统计学意义。结论:俄罗斯北部研究地区青少年MIH患病率明显低于大多数其他国家。然而,患有MIH的青少年表现出明显更高强度的龋齿病变,因此有必要针对MIH制定预防措施。
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引用次数: 0
[Application of BMP-2 for bone regeneration in osteoporosis]. [BMP-2在骨质疏松症骨再生中的应用]。
Q4 Medicine Pub Date : 2025-01-01 DOI: 10.17116/stomat2025104031101
V S Kuznetsova, V A Sinelnikova, A V Vasilyev

This review considers the potential use of bone morphogenetic protein-2 (BMP-2) for bone regeneration in osteoporosis. Studies on the effect of BMP-2 on bone regeneration in vitro and in vivo are analysed. The results of clinical application of osteoinducers and possible complications are described.

本文综述了骨形态发生蛋白-2 (BMP-2)在骨质疏松症骨再生中的潜在应用。分析了BMP-2在体外和体内对骨再生的影响。介绍了骨诱导剂的临床应用结果及可能的并发症。
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引用次数: 0
[Method for determining the activity of a galvanic cell in galvanic syndrome and diseases of the oral mucosa]. [在口腔粘膜的电综合征和疾病中测定电细胞活性的方法]。
Q4 Medicine Pub Date : 2025-01-01 DOI: 10.17116/stomat202510403121
A G Volkov, N Zh Dikopova, V M Grinin, S N Razumova, N A Volkov, G E Amanatidi

The objective: Of this work is to study the effectiveness of a method for determining the activity of a galvanic cell in the absence and presence of galvanic syndrome and diseases of the oral mucosa, the development of which may be associated with the irritating effect of direct electric current.

Material and methods: Three groups of 50 patients were examined. All patients had at least 2 metal structures in the oral cavity. The first group consisted of patients without diseases of the oral mucosa and the absence of complaints specific to galvanic syndrome. The second group included patients without signs of pathological changes in the oral mucosa but with complaints are specific to galvanic syndrome. The third group consisted of patients with diseases of oral mucosa, the development of which could be due to the irritating effect of direct electric current. The electrochemical potential of each metal structure was determined and the difference between the potential obtained was calculated to detect metal structures that could form a galvanic pair. To determine the activity of a galvanic cell formed by galvanic vapors, the hydrogen index of the gingival fluid in the area of these structures was determined.

The results of the study: The difference in the electrochemical potentials of metal structures in the studied groups had no statistically significant differences (p>0.05) and amounted to: 129±24.7 mV in the first group, 138±35.3 mV in the second, 135±19.8 mV in the third. In the first group, 92% of patients had no significant difference in the hydrogen parameters of gingival fluid near pairs of metal structures (p>0.05). The hydrogen values were 6.6±0.26 at the cathode and 6.9±0.35 at the anode. In the second group, 88% of patients showed significant credible differences (p<0.05) in the hydrogen parameters of the gingival fluid near metal structures, at the cathode - 7.9±0.42, and at the anode - 6.3±0.31. In the third group, 86% of patients also showed a high difference in the hydrogen parameters of the gingival fluid near metal structures, at the cathode - 7.8±0.29, at the anode - 6.3±0.22 (p<0.05).

Conclusion: A method for detecting the activity of a galvanic element in the oral cavity, which consists in measuring the hydrogen parameters of the gingival fluid near metal structures forming a galvanic pair, allows you to objectively assess whether the galvanic element is in a passive or active state. In the absence of galvanic syndrome and diseases of the oral mucosa, the detection rate of active galvanic cells was only 8%, wwhile in the presence of galvanic syndrome it was 88%, and in diseases of the oral mucosa it was 86%.

目的:这项工作的目的是研究在没有和存在电偶综合征和口腔粘膜疾病的情况下确定原电池活性方法的有效性,这些疾病的发展可能与直流电的刺激作用有关。材料与方法:将50例患者分为三组进行检查。所有患者口腔内至少有2个金属结构。第一组包括无口腔黏膜疾病和无电偶综合征特异性主诉的患者。第二组包括没有口腔黏膜病理改变迹象的患者,但有特定于电偶综合征的抱怨。第三组为口腔黏膜疾病患者,其发展可能是由于直流电的刺激作用。测定每种金属结构的电化学电位,并计算所得电位之间的差值,以检测可以形成电偶的金属结构。为了确定由电蒸汽形成的原电池的活性,确定了这些结构区域牙龈液的氢指数。研究结果:各组金属结构的电化学电位差异无统计学意义(p < 0.05),第一组为129±24.7 mV,第二组为138±35.3 mV,第三组为135±19.8 mV。在第一组中,92%的患者在金属结构对附近牙龈液的氢参数无显著差异(p < 0.05)。阴极的氢值为6.6±0.26,阳极的氢值为6.9±0.35。在第二组中,88%的患者表现出显著的可信差异(pp结论:一种检测口腔电偶活性的方法,通过测量形成电偶的金属结构附近牙龈液的氢参数,可以客观地评估电偶是处于被动状态还是主动状态。在没有电偶综合征和口腔黏膜疾病的情况下,活跃电偶细胞的检出率仅为8%,而在有电偶综合征的情况下,活跃电偶细胞的检出率为88%,在口腔黏膜疾病中,活跃电偶细胞的检出率为86%。
{"title":"[Method for determining the activity of a galvanic cell in galvanic syndrome and diseases of the oral mucosa].","authors":"A G Volkov, N Zh Dikopova, V M Grinin, S N Razumova, N A Volkov, G E Amanatidi","doi":"10.17116/stomat202510403121","DOIUrl":"10.17116/stomat202510403121","url":null,"abstract":"<p><strong>The objective: </strong>Of this work is to study the effectiveness of a method for determining the activity of a galvanic cell in the absence and presence of galvanic syndrome and diseases of the oral mucosa, the development of which may be associated with the irritating effect of direct electric current.</p><p><strong>Material and methods: </strong>Three groups of 50 patients were examined. All patients had at least 2 metal structures in the oral cavity. The first group consisted of patients without diseases of the oral mucosa and the absence of complaints specific to galvanic syndrome. The second group included patients without signs of pathological changes in the oral mucosa but with complaints are specific to galvanic syndrome. The third group consisted of patients with diseases of oral mucosa, the development of which could be due to the irritating effect of direct electric current. The electrochemical potential of each metal structure was determined and the difference between the potential obtained was calculated to detect metal structures that could form a galvanic pair. To determine the activity of a galvanic cell formed by galvanic vapors, the hydrogen index of the gingival fluid in the area of these structures was determined.</p><p><strong>The results of the study: </strong>The difference in the electrochemical potentials of metal structures in the studied groups had no statistically significant differences (<i>p</i>>0.05) and amounted to: 129±24.7 mV in the first group, 138±35.3 mV in the second, 135±19.8 mV in the third. In the first group, 92% of patients had no significant difference in the hydrogen parameters of gingival fluid near pairs of metal structures (<i>p</i>>0.05). The hydrogen values were 6.6±0.26 at the cathode and 6.9±0.35 at the anode. In the second group, 88% of patients showed significant credible differences (<i>p</i><0.05) in the hydrogen parameters of the gingival fluid near metal structures, at the cathode - 7.9±0.42, and at the anode - 6.3±0.31. In the third group, 86% of patients also showed a high difference in the hydrogen parameters of the gingival fluid near metal structures, at the cathode - 7.8±0.29, at the anode - 6.3±0.22 (<i>p</i><0.05).</p><p><strong>Conclusion: </strong>A method for detecting the activity of a galvanic element in the oral cavity, which consists in measuring the hydrogen parameters of the gingival fluid near metal structures forming a galvanic pair, allows you to objectively assess whether the galvanic element is in a passive or active state. In the absence of galvanic syndrome and diseases of the oral mucosa, the detection rate of active galvanic cells was only 8%, wwhile in the presence of galvanic syndrome it was 88%, and in diseases of the oral mucosa it was 86%.</p>","PeriodicalId":35887,"journal":{"name":"Stomatologiya","volume":"104 3","pages":"21-25"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144733595","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Dynamics of PCR diagnostic indicators after photodynamic treatment]. 【光动力处理后PCR诊断指标的动态变化】。
Q4 Medicine Pub Date : 2025-01-01 DOI: 10.17116/stomat202510404122
F F Losev, E K Krechina, E N Nikolaeva, A V Myagkova

Objective: Evaluation of the effectiveness of treatment of chronic generalized periodontitis by PDT method based on PCR diagnostic data.

Material and methods: A clinical and laboratory study and treatment of chronic generalized periodontitis of moderate severity was conducted in 30 people (16 men and 14 women) aged 35 to 55 years without somatic pathology with orthognathic bite diagnosed according to ICD-10 K05.3. Complex treatment consisted of oral sanitation, removal of dental plaque and curettage of periodontal pockets followed by photodynamic therapy (4 sessions of 10 minutes each). Bacteriological examination was performed before and after PDT. The test material was collected from inflammation sites in the gingival sulcus area and from periodontal pocket areas. DNA determination of Prevotella intermedia, Tannerella forsythia (Bacteroides forsythus), Treponema denticola, Aggregatibacter actinomycetemcomitans (Actinobacillus actinomycetemcomitans) and Porphyromonas gingivalis was performed using the reagent kit Multident-5 by the method of accelerated sample preparation using reagents manufactured by Genlab LLC in accordance with the manufacturer's instructions. The results were assessed by a semi-quantitative method (in points from 0 to 4).

Results: According to PCR diagnostics, a positive trend was observed in patients after PDT treatment. The decrease in the frequency of A. actinomycetemcomitans DNA detection after treatment was not statistically significant. At the same time, A. actinomycetemcomitans was identified in 17 (85%), after therapy in 15 (80%) indivisuals. The frequency of P. intermedia detection after therapy decreased from 15 (40%) to 0 (0%) cases. The frequency of P. gingivalis DNA detection decreased by 1.4 times: from 18 (90%) cases before treatment to 13 (65%) after treatment. One month after PDT, the frequency of P. gingivalis DNA detection decreased by 2 times, and after 3 months by 1.4 times. T. forsythia was detected before treatment in all patients, after treatment in 18 cases (90%). One month after PDT, it decreased significantly and was completely eliminated, which remained the case after 3 months. T. denticola was detected in 16 (80%) patients before treatment and in 14 (70%) people after treatment.

Conclusions: PDT resulted in a significant reduction in the bacterial load in patients with moderate chronic generalized periodontitis.

目的:基于PCR诊断资料评价PDT法治疗慢性广泛性牙周炎的疗效。材料和方法:对30例(男性16例,女性14例)年龄35 ~ 55岁,无躯体病理,根据ICD-10 K05.3诊断为正颌咬伤的慢性广泛性牙周炎进行临床和实验室研究及治疗。综合治疗包括口腔卫生、清除牙菌斑和刮除牙周袋,然后进行光动力治疗(4次,每次10分钟)。PDT前后分别行细菌学检查。试验材料采集于牙龈沟区和牙周袋区炎症部位。使用试剂盒Multident-5,采用Genlab LLC根据制造商说明书生产的试剂,采用加速制样方法,对中间普氏菌、连翘单宁菌(拟连翘杆菌)、齿状密螺旋体、放线菌聚集杆菌(放线菌)和牙龈卟啉单胞菌进行DNA检测。结果采用半定量方法(0 ~ 4分)评定。结果:PCR诊断显示PDT治疗后患者呈阳性趋势。治疗后放线菌酵母DNA检测频率的降低无统计学意义。同时,17例(85%)放线菌comitans经治疗后,15例(80%)单独检出放线菌。治疗后中芽胞杆菌的检出率从15例(40%)下降到0例(0%)。牙龈卟啉单胞菌DNA检测频率从治疗前的18例(90%)下降到治疗后的13例(65%),下降了1.4倍。PDT后1个月,牙龈卟啉单胞菌DNA检测频率下降2倍,3个月后下降1.4倍。所有患者治疗前均检出连翘,治疗后检出连翘18例(90%)。PDT后1个月明显减少,完全消除,3个月后仍是如此。治疗前检出16例(80%),治疗后检出14例(70%)。结论:PDT可显著降低中度慢性全身性牙周炎患者的细菌负荷。
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引用次数: 0
[Features of clinical manifestations of salivary gland pathology in patients after radioiodine therapy]. [放射碘治疗后患者涎腺病理的临床表现特点]。
Q4 Medicine Pub Date : 2025-01-01 DOI: 10.17116/stomat202510404112
A Ya Razumova, A I Yaremenko, S I Kutukova, E V Borodavina, N L Petrov, S A Yaremenko

Objective: The aim the study is determination of the features of the manifestations of sialadenitis that developed during or after radioiodine therapy.

Material and methods: We analyzed the data of 61 patients who received at least one session of radioiodine therapy. The patients were divided into two groups: with and without salivary gland pathology. Patients in the control group underwent scintigraphy and ultrasound examination of the soft tissues of the maxillofacial region and neck, as well as salivary gland structures, once every 3 months (in remission - once a year). When obstruction of the ductal system of the salivary glands was detected, patients underwent diagnostic sialoscopy.

Results: A bilateral lesion of the parotid salivary gland was found in 10 (36%) patients. Damage to the salivary glands developed after receiving at least one dose of radioiodine therapy (2.56 Gbq). The main complaint was an enlargement of the salivary gland. The first symptoms of the disease appeared at initial doses of radionuclide therapy not exceeding 6.77 Gbq(at the minimum dose 2.56 Gbq): the median time for the first symptoms of salivary gland disease was 14.5 (95% CI 11.0-113.0) months (p<0.0001).

Conclusion: The main clinical signs of sialadenitis, which broke down against the background of radioiodine therapy, are impaired saliva outflow, as well as xerostomia. Therefore, the treatment of this pathology should be aimed at restoring the patency of the ductal system and stimulating saliva production.

目的:探讨放射碘治疗期间或治疗后涎腺炎的临床表现特点。材料和方法:我们分析了61例至少接受过一次放射性碘治疗的患者的资料。将患者分为有和无唾液腺病理两组。对照组患者每3个月(缓解期-每年1次)对颌面部及颈部软组织及唾液腺结构进行扫描和超声检查。当检测到唾液腺导管系统阻塞时,患者进行诊断性涎镜检查。结果:双侧腮腺涎腺病变10例(36%)。在接受至少一剂放射性碘治疗(2.56 Gbq)后,唾液腺出现损伤。主要的主诉是唾液腺肿大。在放射性核素治疗初始剂量不超过6.77 Gbq(最低剂量为2.56 Gbq)时出现首发症状,出现涎腺疾病首发症状的中位时间为14.5个月(95% CI 11.0-113.0)。结论:涎腺炎在放射性碘治疗背景下的主要临床症状为唾液流出受损和口干。因此,这种病理的治疗应着眼于恢复导管系统的通畅和刺激唾液的产生。
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引用次数: 0
[The integral analysis of children's dental health by the factor of the living functional area (on the example of the Kursk Region)]. [生活功能区因素对儿童口腔健康的综合分析(以库尔斯克地区为例)]。
Q4 Medicine Pub Date : 2025-01-01 DOI: 10.17116/stomat202510404188
D S Tishkov, V Yu Denisova, V V Denisova, V A Zhurbenko, A E Karlash

Objective: To assess the dental status of pediatric population in Kursk and Zheleznogorsk district and correlation with the functional area of residence.

Material and methods: The study involved 425 patients from 6 to 15 years old, living in regions of different radius from the Mikhailovsky Mining and Processing Plant: proximity of residence 10-30 km (n1 - group 1); 31-50 km (n2 - group 2); more than 50 km - comparison group (n3). Age subgroups were identified within the groups: children with early mixed bite aged 6-8 years (n1=45, n2=41, n3=46), children with late mixed bite aged 9-12 years (n1=48, n2=46, n3=50), children with permanent bite aged 13-15 years (n1=50, n2=48, n3=51).

Results: The prevalence of caries among children is high (n2 - 89.73%; n3 - 89.12%). In the industrial risk zone, this indicator reaches 90.24%. For children of 6-8 years, there was a significant increase in the intensity of the carious process within the designated living areas: DMFT+df n1=5.6 [5.4-5.8] (p<0.001) and n2=5.4 [5.0-5.6] (p=0.0016) exceeds the median value of the comparison group 5.0 [4.7-5.1]. The level of caries resistance was also reduced with 95% probability for patients of Zheleznogorsk district: n1 - 6.1 [5.8; 6.3] (p=0.0014) and n2 - 5.9 [5.4;6.1] (p<0.001).There were no statistically significant differences in children of secondary school age and adolescence with the control group, but a negative trend was identified.

Conclusion: The results obtained demonstrate changes in the dental status of children living near an industrially active area, which is a prerequisite for careful monitoring of their health status.

目的:了解库尔斯克和热列兹诺戈尔斯克地区儿童口腔健康状况及其与居住功能区的关系。材料和方法:该研究涉及425名6至15岁的患者,他们居住在距离米哈伊洛夫斯基采矿和加工厂不同半径的地区:靠近住所10-30公里(n1 - 1组);31-50公里(n2 -第2组);50公里以上-对照组(n3)。组内确定年龄亚组:早期混合咬合儿童6 ~ 8岁(n1=45, n2=41, n3=46),晚期混合咬合儿童9 ~ 12岁(n1=48, n2=46, n3=50),永久性咬合儿童13 ~ 15岁(n1=50, n2=48, n3=51)。结果:儿童龋患病率较高(n2 - 89.73%; n2 - 89.12%)。在工业风险区,该指标达到90.24%。对于6-8岁儿童,指定生活区域内龋齿过程的强度显著增加:DMFT+df n1=5.6 [5.4-5.8] (pn2=5.4 [5.0-5.6]) (p=0.0016)超过对照组5.0[4.7-5.1]的中位数。热列兹诺戈尔斯克地区患者的耐龋水平也有95%的概率下降:n1 - 6.1 [5.8;6.3] (p=0.0014)和n2 - 5.9 [5.4;6.1] (p < 0.05)结论:所得结果反映了工业活动区附近儿童牙齿状况的变化,这是认真监测儿童健康状况的前提。
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Stomatologiya
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