首页 > 最新文献

Stomatologiya最新文献

英文 中文
[Methodology for the use of kinesiological decongestant dressing in double-jaw orthognathic operations]. 双颌正颌手术中使用运动学减充血药的方法学
Q4 Medicine Pub Date : 2025-01-01 DOI: 10.17116/stomat202510405118
T Z Chkadua, P V Libin, N Sh Sufiomarov, Kh Z Tagirova

Objective: Development and implementation into practice of a method for applying a postoperative anti-edematous kinesiological bandage used in extended genioplasty.

Material and methods: A comparative analysis of the effectiveness of the developed method was conducted. Three groups of patients were formed, consisting of 20 people. The first group of patients after surgery used a kinesiological bandage. The second group - a bandage pressure bandage. The third - a hylotherapeutic cold mask. The results were assessed immediately after applying the bandages, on the 5th day after their removal, and also on the 10th day using MSCT examination of the facial skeleton and 3D photographs of the face, analyzed using the «Planmeca ProFace» program.

Results: The average value of the volume of postoperative edema (in cm) on the 5th day after surgery was: 9.4 in the first group; 10.6 in the second group; 10.3 in the third group. On the 10th day: 9.1 in the first group; 10.4 in the second group; 10.1 in the third group.

Conclusion: The results obtained in the three study groups proved that the proposed method of using an anti-edematous kinesiological bandage in extended genioplasty has the most pronounced effectiveness in the postoperative period in extended genioplasty.

目的:发展和实施一种应用于延长膝成形术的术后消肿运动绷带的方法。材料与方法:对所建立方法的有效性进行了对比分析。患者分为三组,每组20人。第一组患者术后使用运动学绷带。第二组-绷带加压绷带。第三种——水疗冷敷。应用绷带后立即评估结果,移除绷带后第5天评估结果,并在第10天使用MSCT检查面部骨骼和面部3D照片,使用«Planmeca ProFace»程序分析结果。结果:术后第5天,第一组患者术后水肿体积(单位cm)平均值为:9.4;第二组10.6例;第三组为10.3。第10天:第一组9.1;第二组为10.4例;第三组10.1例。结论:三个研究组的研究结果证明,所提出的在延长颏成形术中使用消肿运动绷带的方法在延长颏成形术的术后阶段效果最为显著。
{"title":"[Methodology for the use of kinesiological decongestant dressing in double-jaw orthognathic operations].","authors":"T Z Chkadua, P V Libin, N Sh Sufiomarov, Kh Z Tagirova","doi":"10.17116/stomat202510405118","DOIUrl":"https://doi.org/10.17116/stomat202510405118","url":null,"abstract":"<p><strong>Objective: </strong>Development and implementation into practice of a method for applying a postoperative anti-edematous kinesiological bandage used in extended genioplasty.</p><p><strong>Material and methods: </strong>A comparative analysis of the effectiveness of the developed method was conducted. Three groups of patients were formed, consisting of 20 people. The first group of patients after surgery used a kinesiological bandage. The second group - a bandage pressure bandage. The third - a hylotherapeutic cold mask. The results were assessed immediately after applying the bandages, on the 5th day after their removal, and also on the 10th day using MSCT examination of the facial skeleton and 3D photographs of the face, analyzed using the «Planmeca ProFace» program.</p><p><strong>Results: </strong>The average value of the volume of postoperative edema (in cm) on the 5th day after surgery was: 9.4 in the first group; 10.6 in the second group; 10.3 in the third group. On the 10th day: 9.1 in the first group; 10.4 in the second group; 10.1 in the third group.</p><p><strong>Conclusion: </strong>The results obtained in the three study groups proved that the proposed method of using an anti-edematous kinesiological bandage in extended genioplasty has the most pronounced effectiveness in the postoperative period in extended genioplasty.</p>","PeriodicalId":35887,"journal":{"name":"Stomatologiya","volume":"104 5","pages":"18-23"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145423209","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Comparative morphometric analysis of the sizes of the body and branch of the mandible in adolescents with various forms of underdevelopment of the mandible: development of a classification of the degrees of underdevelopment and an algorithm for choosing surgical tactics]. [不同形式下颌骨发育不全的青少年下颌骨体和分支大小的形态计量学比较分析:发育不全程度分类和手术策略选择算法的发展]。
Q4 Medicine Pub Date : 2025-01-01 DOI: 10.17116/stomat202510406265
F F Losev, P I Shapovalov, A A Kulakov, O V Gevorkyan

Objective: To perform a comparative morphometric analysis of mandibular body length and ramus height in adolescents with unilateral mandibular underdevelopment, and to develop a classification of severity grades and an algorithm for surgical treatment planning.

Materials and methods: The study included 50 patients (27 boys and 23 girls) aged 9 to 17 years (mean age 13.4 ± 2.1 years) with unilateral underdevelopment of the mandible of various etiologies. All patients underwent multisection CT of the maxillofacial region with morphometric analysis of key parameters (Go-Me, Co-Go). The obtained values were compared with the normative age indicators identified according to literature data and CT scans of 10 healthy children, and the shortening in millimeters and percentages was calculated.

Results: A quantitative classification of unilateral underdevelopment of the mandible has been developed. With grade I underdevelopment, shortening of the body and/ or branch is less than 10% of the age norm; with grade II, a decrease in size in the range of 10-30%, grade III corresponds to severe underdevelopment with a shortening of more than 30%. A clear relationship between the morphometric degree of shortening and clinical manifestations was established: at grade I, distal bite was observed without pronounced functional disorders.; Grade II revealed a pronounced malocclusion (Angle class II) with deep incisor overlap and crowding of teeth; grade III showed gross changes in the profile of the face with pronounced asymmetry, distal bite and severe functional disorders - impaired chewing, swallowing and speech.

Conclusion: The morphometric classification made it possible to quantify three degrees of underdevelopment of the mandible - mild, moderate and severe - based on shortening of body length and/or height of the branch relative to the age norm. Taking into account the prevailing type of shortening (horizontal, vertical, or combined) provides a more accurate reflection of the clinical picture. Based on the classification, a treatment algorithm has been developed. The proposed approaches standardize the planning and implementation of surgical correction of mandibular underdevelopment in adolescents.

目的:对青少年单侧下颌骨发育不全患者的下颌骨体长和支高进行形态计量学比较分析,并提出严重程度分级及手术治疗方案。材料与方法:本组患者50例,男27例,女23例,年龄9 ~ 17岁(平均13.4±2.1岁),不同原因单侧下颌骨发育不全。所有患者均行颌面部区域多层CT扫描,并对关键参数(Go-Me, Co-Go)进行形态计量学分析。将所得值与根据文献资料和10例健康儿童CT扫描确定的规范年龄指标进行比较,计算缩短的毫米和百分比。结果:对单侧下颌骨发育不全进行了定量分类。I级发育不足,体和/或分支缩短小于年龄标准的10%;II级为缩小10 ~ 30%,III级为严重欠发达,缩小30%以上。形态学缩短程度与临床表现之间建立了明确的关系:在I级时,观察到远端咬合未出现明显的功能障碍;II级显示明显的错牙合(角II级),有深切牙重叠和牙齿拥挤;III级表现为面部轮廓的明显改变,明显不对称,远端咬合和严重的功能障碍-咀嚼,吞咽和言语受损。结论:形态计量学分类方法可以根据相对于年龄标准的躯干长度和/或分支高度的缩短来量化下颌骨发育不全的轻度、中度和重度。考虑到常见的缩短类型(水平、垂直或组合)可以更准确地反映临床情况。在此基础上,提出了一种处理算法。提出的方法规范了青少年下颌发育不全手术矫治的计划和实施。
{"title":"[Comparative morphometric analysis of the sizes of the body and branch of the mandible in adolescents with various forms of underdevelopment of the mandible: development of a classification of the degrees of underdevelopment and an algorithm for choosing surgical tactics].","authors":"F F Losev, P I Shapovalov, A A Kulakov, O V Gevorkyan","doi":"10.17116/stomat202510406265","DOIUrl":"https://doi.org/10.17116/stomat202510406265","url":null,"abstract":"<p><strong>Objective: </strong>To perform a comparative morphometric analysis of mandibular body length and ramus height in adolescents with unilateral mandibular underdevelopment, and to develop a classification of severity grades and an algorithm for surgical treatment planning.</p><p><strong>Materials and methods: </strong>The study included 50 patients (27 boys and 23 girls) aged 9 to 17 years (mean age 13.4 ± 2.1 years) with unilateral underdevelopment of the mandible of various etiologies. All patients underwent multisection CT of the maxillofacial region with morphometric analysis of key parameters (Go-Me, Co-Go). The obtained values were compared with the normative age indicators identified according to literature data and CT scans of 10 healthy children, and the shortening in millimeters and percentages was calculated.</p><p><strong>Results: </strong>A quantitative classification of unilateral underdevelopment of the mandible has been developed. With grade I underdevelopment, shortening of the body and/ or branch is less than 10% of the age norm; with grade II, a decrease in size in the range of 10-30%, grade III corresponds to severe underdevelopment with a shortening of more than 30%. A clear relationship between the morphometric degree of shortening and clinical manifestations was established: at grade I, distal bite was observed without pronounced functional disorders.; Grade II revealed a pronounced malocclusion (Angle class II) with deep incisor overlap and crowding of teeth; grade III showed gross changes in the profile of the face with pronounced asymmetry, distal bite and severe functional disorders - impaired chewing, swallowing and speech.</p><p><strong>Conclusion: </strong>The morphometric classification made it possible to quantify three degrees of underdevelopment of the mandible - mild, moderate and severe - based on shortening of body length and/or height of the branch relative to the age norm. Taking into account the prevailing type of shortening (horizontal, vertical, or combined) provides a more accurate reflection of the clinical picture. Based on the classification, a treatment algorithm has been developed. The proposed approaches standardize the planning and implementation of surgical correction of mandibular underdevelopment in adolescents.</p>","PeriodicalId":35887,"journal":{"name":"Stomatologiya","volume":"104 6. Vyp. 2","pages":"65-72"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145726512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Evaluation of osteoinductive potential of materials with BMP-2]. [利用BMP-2评价材料的成骨诱导电位]。
Q4 Medicine Pub Date : 2025-01-01 DOI: 10.17116/stomat202510406219
V S Kuznetsova, A V Vasilyev, T B Bukharova, I A Nedorubova, A V Gromov, D V Goldstein

Objective: To evaluate the osteogenic properties of porous polylactide granules (PLA) and hydroxyapatite granules (HA) impregnated with recombinant bone morphogenetic protein-2 (BMP-2) in vitro and in vivo.

Materials and methods: Osteogenic differentiation in the presence of polylactide granules was studied in a culture of mesenchymal stromal cells obtained from rat adipose tissue (MSC-AT). For this purpose, the expression of the Bmp2, Spp1, and Bglap genes and the production of osteocalcin and osteopontin proteins were analyzed, as well as the mineralization of the intracellular matrix. In vivo, the osteogenic properties of PLA granules and two types of hydroxyapatite with BMP-2 were studied using a model of orthotopic osteogenesis. After 28 days, histological analysis and morphometry were performed to assess the volume of newly formed bone tissue and connective tissue surrounding and sprouting into the material.

Results: Polylactide granules with BMP-2 stimulated the osteogenic differentiation of MSC-AT, caused an increase in the expression of genes for markers of osteogenic differentiation, Bmp2, Spp1 and Bglap, and the production of proteins osteopontin and osteocalcin, and contributed to the mineralization of the extracellular matrix. In vivo, the material based on polylactide granules with BMP-2 led to the formation of a larger volume of bone tissue, compared with hydroxyapatite HA-1 granules, and contributed to less fouling of connective tissue.

Conclusion: Highly porous polylactide granules impregnated with BMP-2 demonstrated osteogenic properties in in vitro studies, and were also characterized by better osteoinductive properties compared with impregnated BMP-2 hydroxyapatite granules in vivo. Thus, polylactide granules with recombinant BMP-2 can be used to produce highly effective bone graft materials for the restoration of bone defects in dentistry and maxillofacial surgery.

目的:评价重组骨形态发生蛋白-2 (BMP-2)浸渍多孔聚乳酸颗粒(PLA)和羟基磷灰石颗粒(HA)的体外和体内成骨性能。材料和方法:在大鼠脂肪组织间充质间质细胞(MSC-AT)培养中,研究了聚丙交酯颗粒存在下的成骨分化。为此,我们分析了Bmp2、Spp1和Bglap基因的表达、骨钙素和骨桥蛋白的产生以及细胞内基质的矿化。在体内,采用原位成骨模型研究了PLA颗粒和两种羟基磷灰石BMP-2的成骨性能。28 d后,进行组织学分析和形态测定,以评估材料周围和萌发的新形成骨组织和结缔组织的体积。结果:BMP-2聚乳酸颗粒刺激MSC-AT成骨分化,使成骨分化标志物Bmp2、Spp1和Bglap基因表达增加,骨桥蛋白和骨钙素蛋白产生增加,促进细胞外基质矿化。在体内,与羟基磷灰石HA-1颗粒相比,以BMP-2聚乳酸颗粒为基础的材料可形成更大体积的骨组织,并有助于减少结缔组织的污染。结论:BMP-2浸渍的高孔聚乳酸颗粒在体外研究中表现出成骨性能,并且与BMP-2羟基磷灰石浸渍颗粒相比,在体内具有更好的骨诱导性能。因此,含有重组BMP-2的聚乳酸颗粒可用于牙科和颌面外科骨缺损的修复,制备高效的骨移植材料。
{"title":"[Evaluation of osteoinductive potential of materials with BMP-2].","authors":"V S Kuznetsova, A V Vasilyev, T B Bukharova, I A Nedorubova, A V Gromov, D V Goldstein","doi":"10.17116/stomat202510406219","DOIUrl":"https://doi.org/10.17116/stomat202510406219","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the osteogenic properties of porous polylactide granules (PLA) and hydroxyapatite granules (HA) impregnated with recombinant bone morphogenetic protein-2 (BMP-2) <i>in vitro</i> and <i>in vivo</i>.</p><p><strong>Materials and methods: </strong>Osteogenic differentiation in the presence of polylactide granules was studied in a culture of mesenchymal stromal cells obtained from rat adipose tissue (MSC-AT). For this purpose, the expression of the <i>Bmp2, Spp1</i>, and <i>Bglap</i> genes and the production of osteocalcin and osteopontin proteins were analyzed, as well as the mineralization of the intracellular matrix. <i>In vivo</i>, the osteogenic properties of PLA granules and two types of hydroxyapatite with BMP-2 were studied using a model of orthotopic osteogenesis. After 28 days, histological analysis and morphometry were performed to assess the volume of newly formed bone tissue and connective tissue surrounding and sprouting into the material.</p><p><strong>Results: </strong>Polylactide granules with BMP-2 stimulated the osteogenic differentiation of MSC-AT, caused an increase in the expression of genes for markers of osteogenic differentiation, <i>Bmp2, Spp1</i> and <i>Bglap</i>, and the production of proteins osteopontin and osteocalcin, and contributed to the mineralization of the extracellular matrix. In vivo, the material based on polylactide granules with BMP-2 led to the formation of a larger volume of bone tissue, compared with hydroxyapatite HA-1 granules, and contributed to less fouling of connective tissue.</p><p><strong>Conclusion: </strong>Highly porous polylactide granules impregnated with BMP-2 demonstrated osteogenic properties in in vitro studies, and were also characterized by better osteoinductive properties compared with impregnated BMP-2 hydroxyapatite granules <i>in vivo</i>. Thus, polylactide granules with recombinant BMP-2 can be used to produce highly effective bone graft materials for the restoration of bone defects in dentistry and maxillofacial surgery.</p>","PeriodicalId":35887,"journal":{"name":"Stomatologiya","volume":"104 6. Vyp. 2","pages":"19-24"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145726540","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Optimization of the protocol for premaxillary repositioning in patients with bilateral cleft lip and palate]. [双侧唇腭裂患者上颌前复位方案的优化]。
Q4 Medicine Pub Date : 2025-01-01 DOI: 10.17116/stomat202510406244
A L Ivanov, A P Romanenko, N V Starikova, N V Udalova

Objective: To implement an optimized surgical protocol and evaluate the effectiveness of treatment in patients with bilateral cleft lip and palate and severe premaxillary displacement during the preparation stage for alveolar bone grafting of the maxilla.

Materials and methods: A standardized protocol for correcting significant premaxillary displacement was applied in 15 patients aged 7 to 15 years who underwent surgery at the Central Research Institute of Stomatology and Maxillofacial Surgery. The protocol included model surgery, the fabrication of an individual occlusal splint for fixation, and an atraumatic surgical approach. Inclusion criteria were significant premaxillary protrusion, vertical displacement, or rotation, as well as the impossibility of achieving proper alignment through orthodontic compensation alone to prepare for alveolar bone grafting of the maxilla. Effectiveness was assessed based on the following criteria: achieving the planned position of the premaxilla, preservation of maxillary blood supply, creation of conditions for two-stage alveolar bone grafting without the need for additional orthodontic or surgical correction.

Results: The planned position of the premaxilla was achieved in 100% of cases. Vascularization of the premaxilla was preserved in all patients. One case of partial ischemia of the premaxilla was observed in the early postoperative period, likely due to multiple previous surgeries on the upper lip. Nevertheless, full rehabilitation was achieved. Anatomically correct positioning of the maxilla was ensured in all patients, enabling alveolar bone grafting without the need for additional correction.

Conclusion: The proposed protocol for surgical repositioning of the premaxilla in patients with bilateral cleft lip and palate demonstrates high clinical effectiveness due to increased accuracy and standardization. The use of preoperative modeling, an individual occlusal splint for fixation, and well-defined inclusion criteria minimizes intraoperative risks, ensures stability of the premaxilla, and creates optimal conditions for subsequent bone grafting.

目的:对双侧唇腭裂及上颌前移位患者在上颌牙槽骨移植准备阶段的手术方案进行优化,并评价其治疗效果。材料和方法:在中央口腔颌面外科研究所接受手术的15例7 ~ 15岁的患者中应用标准化的矫正明显的上颌前移位的方案。该方案包括模型手术,制作单独的咬合夹板进行固定,以及无创伤的手术入路。纳入标准为明显的上颌前突、垂直位移或旋转,以及仅通过正畸补偿无法达到正确对齐,为上颌牙槽骨移植做准备。有效性评估基于以下标准:实现前颌骨的计划位置,保留上颌血液供应,为两阶段牙槽骨移植创造条件,而无需额外的正畸或手术矫正。结果:上颌前牙100%达到预定位置。所有患者均保留了上颌骨前血管的形成。术后早期观察到1例上颌骨局部缺血,可能是由于先前多次上唇手术所致。尽管如此,还是完全康复了。所有患者上颌骨的解剖位置正确,无需额外矫正即可进行牙槽骨移植。结论:所提出的双侧唇腭裂患者上颌骨手术复位方案准确性和规范化程度提高,临床效果良好。使用术前建模、单独的咬合夹板固定和明确的纳入标准可以最大限度地减少术中风险,确保前颌的稳定性,并为后续植骨创造最佳条件。
{"title":"[Optimization of the protocol for premaxillary repositioning in patients with bilateral cleft lip and palate].","authors":"A L Ivanov, A P Romanenko, N V Starikova, N V Udalova","doi":"10.17116/stomat202510406244","DOIUrl":"https://doi.org/10.17116/stomat202510406244","url":null,"abstract":"<p><strong>Objective: </strong>To implement an optimized surgical protocol and evaluate the effectiveness of treatment in patients with bilateral cleft lip and palate and severe premaxillary displacement during the preparation stage for alveolar bone grafting of the maxilla.</p><p><strong>Materials and methods: </strong>A standardized protocol for correcting significant premaxillary displacement was applied in 15 patients aged 7 to 15 years who underwent surgery at the Central Research Institute of Stomatology and Maxillofacial Surgery. The protocol included model surgery, the fabrication of an individual occlusal splint for fixation, and an atraumatic surgical approach. Inclusion criteria were significant premaxillary protrusion, vertical displacement, or rotation, as well as the impossibility of achieving proper alignment through orthodontic compensation alone to prepare for alveolar bone grafting of the maxilla. Effectiveness was assessed based on the following criteria: achieving the planned position of the premaxilla, preservation of maxillary blood supply, creation of conditions for two-stage alveolar bone grafting without the need for additional orthodontic or surgical correction.</p><p><strong>Results: </strong>The planned position of the premaxilla was achieved in 100% of cases. Vascularization of the premaxilla was preserved in all patients. One case of partial ischemia of the premaxilla was observed in the early postoperative period, likely due to multiple previous surgeries on the upper lip. Nevertheless, full rehabilitation was achieved. Anatomically correct positioning of the maxilla was ensured in all patients, enabling alveolar bone grafting without the need for additional correction.</p><p><strong>Conclusion: </strong>The proposed protocol for surgical repositioning of the premaxilla in patients with bilateral cleft lip and palate demonstrates high clinical effectiveness due to increased accuracy and standardization. The use of preoperative modeling, an individual occlusal splint for fixation, and well-defined inclusion criteria minimizes intraoperative risks, ensures stability of the premaxilla, and creates optimal conditions for subsequent bone grafting.</p>","PeriodicalId":35887,"journal":{"name":"Stomatologiya","volume":"104 6. Vyp. 2","pages":"44-50"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145726590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Laboratory study of the sealing ability of materials used in retrograde root filling]. [逆行牙根充填材料密封能力的实验室研究]。
Q4 Medicine Pub Date : 2025-01-01 DOI: 10.17116/stomat20251040615
L A Nadzharyan, A V Vasilyev, V A Badalyan, A S Galkin, A V Mironov, F F Losev

Objective: To assess the sealing properties of the most commonly used materials for retrograde filling using a novel reproducible and standardized laboratory testing method.

Materials and methods: The study included 36 intact teeth divided into four experimental groups according to the type of filling material used (Dia-Root BioMTA, Biodentine, Trioxident, Ketac Cem) and two control groups consisting of intact teeth with cleaned and pulp-filled cavities. Sealing ability was evaluated through visual inspection and spectrophotometric analysis of dye penetration over a period of one month.

Results: No dye penetration through the retrograde filling was observed in any of the experimental groups, confirming the high sealing capacity of the materials. Changes in environmental pH from neutral to acidic did not significantly affect permeability.

Conclusion: All tested materials demonstrated reliable sealing of the retrograde cavity, indicating their suitability for use in apical surgery.

目的:采用一种新颖的、可重复的、标准化的实验室测试方法,评价最常用的逆行充填材料的密封性能。材料与方法:36颗完整牙根据所使用的填充物类型分为4个实验组(Dia-Root BioMTA、Biodentine、Trioxident、Ketac Cem), 2个对照组为清洁牙槽并充填牙髓的完整牙。在一个月的时间里,通过目视检查和染料渗透的分光光度分析来评估密封能力。结果:各实验组均未观察到染料通过逆行充填,证实了材料的高密封能力。环境pH值从中性到酸性的变化对渗透性没有显著影响。结论:所有试验材料均表现出可靠的逆行腔密封效果,适合用于根尖手术。
{"title":"[Laboratory study of the sealing ability of materials used in retrograde root filling].","authors":"L A Nadzharyan, A V Vasilyev, V A Badalyan, A S Galkin, A V Mironov, F F Losev","doi":"10.17116/stomat20251040615","DOIUrl":"https://doi.org/10.17116/stomat20251040615","url":null,"abstract":"<p><strong>Objective: </strong>To assess the sealing properties of the most commonly used materials for retrograde filling using a novel reproducible and standardized laboratory testing method.</p><p><strong>Materials and methods: </strong>The study included 36 intact teeth divided into four experimental groups according to the type of filling material used (Dia-Root BioMTA, Biodentine, Trioxident, Ketac Cem) and two control groups consisting of intact teeth with cleaned and pulp-filled cavities. Sealing ability was evaluated through visual inspection and spectrophotometric analysis of dye penetration over a period of one month.</p><p><strong>Results: </strong>No dye penetration through the retrograde filling was observed in any of the experimental groups, confirming the high sealing capacity of the materials. Changes in environmental pH from neutral to acidic did not significantly affect permeability.</p><p><strong>Conclusion: </strong>All tested materials demonstrated reliable sealing of the retrograde cavity, indicating their suitability for use in apical surgery.</p>","PeriodicalId":35887,"journal":{"name":"Stomatologiya","volume":"104 6","pages":"5-10"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145769275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[The need for bone graft materials in Russia, taking into account the prevalence of bone defects and market analysis]. 【俄罗斯对骨移植材料的需求,考虑到骨缺损的普遍性及市场分析】。
Q4 Medicine Pub Date : 2025-01-01 DOI: 10.17116/stomat202510406155
A B Kazumova, A V Vasilyev, V S Kuznetsova, A V Mironov, A A Kulakov, F F Losev

The review summarizes the disparate data on the prevalence of bone defects and the need for bone graft materials. Data from publicly available sources has been analyzed. Parallels have been drawn between the structure of the prevalence of bone lesions and the volume of the market for bone graft materials. An approximation of the demand for bone graft materials in Russia is given.

这篇综述总结了关于骨缺损患病率和骨移植材料需求的不同数据。对来自公开来源的数据进行了分析。在骨病变流行的结构和骨移植材料的市场数量之间已经得出了相似之处。给出了俄罗斯对骨移植材料需求的近似估计。
{"title":"[The need for bone graft materials in Russia, taking into account the prevalence of bone defects and market analysis].","authors":"A B Kazumova, A V Vasilyev, V S Kuznetsova, A V Mironov, A A Kulakov, F F Losev","doi":"10.17116/stomat202510406155","DOIUrl":"https://doi.org/10.17116/stomat202510406155","url":null,"abstract":"<p><p>The review summarizes the disparate data on the prevalence of bone defects and the need for bone graft materials. Data from publicly available sources has been analyzed. Parallels have been drawn between the structure of the prevalence of bone lesions and the volume of the market for bone graft materials. An approximation of the demand for bone graft materials in Russia is given.</p>","PeriodicalId":35887,"journal":{"name":"Stomatologiya","volume":"104 6","pages":"55-59"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145769368","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Vitamin D role in oral cavity diseases]. [维生素 D 在口腔疾病中的作用]。
Q4 Medicine Pub Date : 2025-01-01 DOI: 10.17116/stomat202510401181
A V Ermakov, S A Katrechko, Y I Zablotskaya, V V Molchanova, V I Novitskaya

The purpose of this scientific article is to analyze the scientific literature aimed at identifying the relationship between vitamin D levels in the body and diseases of the oral organs, in order to determine the potential impact of vitamin D deficiency on their development. Special attention is paid to the development of recommendations for maintaining optimal vitamin D levels for various population groups in order to strengthen both general health and prevent diseases of the oral cavity.

这篇科学文章的目的是分析旨在确定体内维生素D水平与口腔器官疾病之间关系的科学文献,以确定维生素D缺乏对其发展的潜在影响。特别注意为不同人群制定维持最佳维生素D水平的建议,以加强一般健康和预防口腔疾病。
{"title":"[Vitamin D role in oral cavity diseases].","authors":"A V Ermakov, S A Katrechko, Y I Zablotskaya, V V Molchanova, V I Novitskaya","doi":"10.17116/stomat202510401181","DOIUrl":"10.17116/stomat202510401181","url":null,"abstract":"<p><p>The purpose of this scientific article is to analyze the scientific literature aimed at identifying the relationship between vitamin D levels in the body and diseases of the oral organs, in order to determine the potential impact of vitamin D deficiency on their development. Special attention is paid to the development of recommendations for maintaining optimal vitamin D levels for various population groups in order to strengthen both general health and prevent diseases of the oral cavity.</p>","PeriodicalId":35887,"journal":{"name":"Stomatologiya","volume":"104 1","pages":"81-86"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143524747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Comparison of diagnostic methods and the initial stage of treatment in patients with temporomandibular joint dysfunction]. [颞下颌关节功能障碍患者诊断方法及初期治疗的比较]。
Q4 Medicine Pub Date : 2025-01-01 DOI: 10.17116/stomat202510402159
M A Chibisova, L A Yermolayeva, V A Zheleznyak, A V Nikolayev, A V Pavlov, S Y Kuyumchian

The aim the study. The aim of the study was to conduct a comparative analysis of methods for determining the optimal individual position of the mandible using a hydrostatic mouth guard and transcutaneous electrical stimulation (TENS) techniques.

Material and methods: The study comprised 188 patients with musculoskeletal and articular dysfunction of the TMJ. The subject of the study is cone beam computed tomography and magnetic resonance imaging of the TMJ of these patients. Before starting treatment, all patients underwent magnetic resonance imaging of the TMJ with functional tests (in the open and closed mouth position) and seizure of the masticatory muscles.

Results: It was found that the results of the therapeutic and diagnostic procedure for finding the optimal position of the lower jaw using a hydrostatic mouth guard and the TENS method are comparable to each other.

Conclusion: CBCT and TMJ MRI are informative diagnostic tools that can be effectively used in the diagnosis and treatment of patients with musculoskeletal dysfunction. Methods for determining the optimal position of the mandible using a hydrostatic mouth guard and TENS have shown their effectiveness at the therapeutic and diagnostic stage of rehabilitation of patients with musculoskeletal dysfunction of the TMJ.

目的是研究。本研究的目的是对使用静液护嘴器和经皮电刺激(TENS)技术确定下颌骨最佳个体位置的方法进行比较分析。材料和方法:本研究纳入188例颞下颌关节肌肉骨骼和关节功能障碍患者。本研究的主题是这些患者的颞下颌关节的锥形束计算机断层扫描和磁共振成像。在开始治疗之前,所有患者都接受了TMJ的磁共振成像,并进行了功能测试(张嘴和闭口位)和咀嚼肌的发作。结果:应用静液护口器和TENS法寻找下颌最佳位置的治疗和诊断结果具有可比性。结论:CBCT和TMJ MRI是一种信息丰富的诊断工具,可有效地用于肌肉骨骼功能障碍患者的诊断和治疗。使用静液护嘴器和TENS确定下颌最佳位置的方法在颞下颌关节肌肉骨骼功能障碍患者康复的治疗和诊断阶段显示出其有效性。
{"title":"[Comparison of diagnostic methods and the initial stage of treatment in patients with temporomandibular joint dysfunction].","authors":"M A Chibisova, L A Yermolayeva, V A Zheleznyak, A V Nikolayev, A V Pavlov, S Y Kuyumchian","doi":"10.17116/stomat202510402159","DOIUrl":"https://doi.org/10.17116/stomat202510402159","url":null,"abstract":"<p><p>The aim the study. The aim of the study was to conduct a comparative analysis of methods for determining the optimal individual position of the mandible using a hydrostatic mouth guard and transcutaneous electrical stimulation (TENS) techniques.</p><p><strong>Material and methods: </strong>The study comprised 188 patients with musculoskeletal and articular dysfunction of the TMJ. The subject of the study is cone beam computed tomography and magnetic resonance imaging of the TMJ of these patients. Before starting treatment, all patients underwent magnetic resonance imaging of the TMJ with functional tests (in the open and closed mouth position) and seizure of the masticatory muscles.</p><p><strong>Results: </strong>It was found that the results of the therapeutic and diagnostic procedure for finding the optimal position of the lower jaw using a hydrostatic mouth guard and the TENS method are comparable to each other.</p><p><strong>Conclusion: </strong>CBCT and TMJ MRI are informative diagnostic tools that can be effectively used in the diagnosis and treatment of patients with musculoskeletal dysfunction. Methods for determining the optimal position of the mandible using a hydrostatic mouth guard and TENS have shown their effectiveness at the therapeutic and diagnostic stage of rehabilitation of patients with musculoskeletal dysfunction of the TMJ.</p>","PeriodicalId":35887,"journal":{"name":"Stomatologiya","volume":"104 2","pages":"59-63"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144188197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Evaluation of periodontal status in patients with liver cirrhosis]. 肝硬化患者牙周状况的评价
Q4 Medicine Pub Date : 2025-01-01 DOI: 10.17116/stomat20251040216
E Y Diachkova, S V Tarasenko, Ch S Pavlov, K A Gorshkov, A D Abdurakhmanova, E M Tumanova

Objective: The aim of the study was to assess the dental status, including the condition of periodontal tissues, in patients with liver cirrhosis.

Material and methods: Based at the Federal State Autonomous Educational Institution of Higher Education of the First Moscow State Medical University named after I.M. Sechenov a dental examination of 52 patients with liver cirrhosis of various etiologies was conducted. The main diagnosis was established based on the results of biochemical blood parameters and ultrasound examination of the abdominal organs, according to which the patients had all 3 classes of liver cirrhosis according to Child-Pugh.

Results: Comparison of the periodontal index in groups depending on the severity of liver cirrhosis showed a significant difference between groups (p<0.05): the maximum was determined in patients with Child-Pugh C (59±0.14 percentage), the minimum - with Child-Pugh A (36.4±0.13 percentage). Comparison of periodontal pocket depth (PD index) in groups depending on the degree of severity showed a significant difference between groups (p<0.05): the maximum was determined in patients with Child-Pugh C (4.02 mm), the minimum - in Child-Pugh A (2.96 mm). Comparison of clinical loss of attachment (CAL index) in groups depending on the degree of severity showed a significant difference between groups (p<0.05): the maximum was determined in patients with Child-Pugh C (-4.1 mm), the minimum - at Child-Pugh A (-2.8 mm).

Conclusion: Based on the results of the study, the presence of a direct connection between periodontitis and the severity of liver cirrhosis could not be excluded.

目的:本研究旨在评估肝硬化患者的牙齿状况,包括牙周组织状况。材料和方法:在以I.M.谢切诺夫命名的莫斯科第一医科大学联邦国家高等教育自治教育机构,对52名不同病因的肝硬化患者进行了牙科检查。主要依据血液生化指标及腹部脏器超声检查结果进行诊断,根据Child-Pugh分级,患者肝硬化3级均为肝硬化。结果:不同肝硬化严重程度组间牙周指数比较差异有统计学意义(ppp)结论:根据本研究结果,不能排除牙周炎与肝硬化严重程度之间存在直接联系。
{"title":"[Evaluation of periodontal status in patients with liver cirrhosis].","authors":"E Y Diachkova, S V Tarasenko, Ch S Pavlov, K A Gorshkov, A D Abdurakhmanova, E M Tumanova","doi":"10.17116/stomat20251040216","DOIUrl":"10.17116/stomat20251040216","url":null,"abstract":"<p><strong>Objective: </strong>The aim of the study was to assess the dental status, including the condition of periodontal tissues, in patients with liver cirrhosis.</p><p><strong>Material and methods: </strong>Based at the Federal State Autonomous Educational Institution of Higher Education of the First Moscow State Medical University named after I.M. Sechenov a dental examination of 52 patients with liver cirrhosis of various etiologies was conducted. The main diagnosis was established based on the results of biochemical blood parameters and ultrasound examination of the abdominal organs, according to which the patients had all 3 classes of liver cirrhosis according to Child-Pugh.</p><p><strong>Results: </strong>Comparison of the periodontal index in groups depending on the severity of liver cirrhosis showed a significant difference between groups (<i>p</i><0.05): the maximum was determined in patients with Child-Pugh C (59±0.14 percentage), the minimum - with Child-Pugh A (36.4±0.13 percentage). Comparison of periodontal pocket depth (PD index) in groups depending on the degree of severity showed a significant difference between groups (<i>p</i><0.05): the maximum was determined in patients with Child-Pugh C (4.02 mm), the minimum - in Child-Pugh A (2.96 mm). Comparison of clinical loss of attachment (CAL index) in groups depending on the degree of severity showed a significant difference between groups (<i>p</i><0.05): the maximum was determined in patients with Child-Pugh C (-4.1 mm), the minimum - at Child-Pugh A (-2.8 mm).</p><p><strong>Conclusion: </strong>Based on the results of the study, the presence of a direct connection between periodontitis and the severity of liver cirrhosis could not be excluded.</p>","PeriodicalId":35887,"journal":{"name":"Stomatologiya","volume":"104 2","pages":"6-10"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144188199","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Attendance of oral surgeons per one inhabitant per year in the subjects of the Russian Federation in 2017-2023]. [2017-2023年俄罗斯联邦各主体每年每一居民口腔外科医生的就诊人数]。
Q4 Medicine Pub Date : 2025-01-01 DOI: 10.17116/stomat202510403153
A A Kulakov, B Sh Abakarov, M A Ivanova

Objective: The aim of the study was to investigate the dynamics of attendance of oral surgeons in the subjects of the Russian Federation per one inhabitant per year.

Material and methods: The data of statistical compilations of the Ministry of Health of Russia on resource provision in federal districts and subjects of the Russian Federation for 2018, 2020, 2022 and 2024 were used in the work.

Results: In the Russian Federation the attendance of oral surgeons per resident per year decreased by 9.7% from 2017 to 2023/ In most federal districts, the dynamics of the attendance rate of oral surgeons per one inhabitant for the period from 2017 to 2023 is comparable to the trend for the country as a whole, except for the North Caucasus, where there was an increase of the indicator by 12.6% for the same period. During the COVID-19 pandemic, the attendance rate decreased by 10.5% in 84.7% of the subjects, after the pandemic it increased in 56.5, decreased in 38.8, and stabilized in 4.7% of federal districts.

Conclusions: The results of the study show the ambiguity of the situation on the attendance of oral surgeons in the subjects of the Russian Federation, which is probably related to the age characteristics of patients and the accessibiility of specialized medical care to the population.

目的:本研究的目的是调查俄罗斯联邦每年每一位居民口腔外科医生的就诊动态。材料和方法:在工作中使用了俄罗斯卫生部关于2018年、2020年、2022年和2024年俄罗斯联邦联邦区和科目资源供应的统计汇编数据。结果:在俄罗斯联邦,从2017年到2023年,每位居民每年的口腔外科医生就诊率下降了9.7% /在大多数联邦区,2017年至2023年期间每位居民的口腔外科医生就诊率的动态与整个国家的趋势相当,除了北高加索地区,该指标同期增长了12.6%。新冠肺炎大流行期间,84.7%的受试者的出勤率下降了10.5%,大流行后,56.5的受试者出勤率上升,38.8的受试者出勤率下降,4.7%的联邦区出勤率稳定。结论:研究结果表明,在俄罗斯联邦的受试者中,口腔外科医生的就诊情况不明确,这可能与患者的年龄特征和人口获得专门医疗护理的机会有关。
{"title":"[Attendance of oral surgeons per one inhabitant per year in the subjects of the Russian Federation in 2017-2023].","authors":"A A Kulakov, B Sh Abakarov, M A Ivanova","doi":"10.17116/stomat202510403153","DOIUrl":"10.17116/stomat202510403153","url":null,"abstract":"<p><strong>Objective: </strong>The aim of the study was to investigate the dynamics of attendance of oral surgeons in the subjects of the Russian Federation per one inhabitant per year.</p><p><strong>Material and methods: </strong>The data of statistical compilations of the Ministry of Health of Russia on resource provision in federal districts and subjects of the Russian Federation for 2018, 2020, 2022 and 2024 were used in the work.</p><p><strong>Results: </strong>In the Russian Federation the attendance of oral surgeons per resident per year decreased by 9.7% from 2017 to 2023/ In most federal districts, the dynamics of the attendance rate of oral surgeons per one inhabitant for the period from 2017 to 2023 is comparable to the trend for the country as a whole, except for the North Caucasus, where there was an increase of the indicator by 12.6% for the same period. During the COVID-19 pandemic, the attendance rate decreased by 10.5% in 84.7% of the subjects, after the pandemic it increased in 56.5, decreased in 38.8, and stabilized in 4.7% of federal districts.</p><p><strong>Conclusions: </strong>The results of the study show the ambiguity of the situation on the attendance of oral surgeons in the subjects of the Russian Federation, which is probably related to the age characteristics of patients and the accessibiility of specialized medical care to the population.</p>","PeriodicalId":35887,"journal":{"name":"Stomatologiya","volume":"104 3","pages":"53-56"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144733589","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Stomatologiya
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1