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An Improved Peer-Review System to Compensate for Scientific Misconduct in Health-Sensitive Topics. 改进的同行评议制度以补偿健康敏感话题中的科学不端行为。
IF 5.5 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2023-01-01 DOI: 10.3389/phrs.2023.1605601
Alessandro Rovetta, Rossana Garavaglia, Alessandro Vitale, Ettore Meccia, Behailu Terefe Tesfaye, Paolo Mezzana, Vincenzo Accurso
In December 2021, one of the authors of the present paper (AR) took part in the peer review of the paper “Safety and immunogenicity of an inactivated virus particle vaccine for SARS-CoV-2, BIV1CovIran: findings from double-blind, randomized, placebo-controlled, phase I and II clinical trials among healthy adults” for the BMJ Open [1, 2]. The manuscript described clinical phases I and II of the COVID-19 vaccine BIV1-CovIran by Shifa Pharmed Industrial Group. The article was accepted for publication in March 2021 after three review rounds, with a total of six reviewers involved. On May 2022, AR received an email from Yeganeh Torbati, a Washington Post reporter who was investigating the development of BIV1-CovIran. Torbati asked AR for a general opinion about the data presented in the above article. AR replied that no serious anomalies were highlighted, although he specified that the peer review process was too superficial to guarantee complete integrity. Subsequently, through an article published in the Washington Post in August 2022, Torbati disclosed serious misconduct dynamics [3]. In support of her claims, an official correction was published in the BMJ Open in November 2022, in which the authors were forced to admit various conflicts of interest and the occurrence of vaccine-related adverse effects [1]. The relevant fact is that not even six peer reviewers and one editor have discovered such a hidden scenario. This is not intended to blame the journal or the reviewers but only to denounce that the world of scientific publication is currently subject to easy ethical violations. Although financial relationships can markedly bias biomedical research, marginal importance is given to this aspect [4, 5]. In this regard, this letter proposes a set of practices to counteract some major integrity problems.
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引用次数: 2
Challenges for Developing Palliative Care Services in Resource- Limited Settings of Kazakhstan. 在哈萨克斯坦资源有限的环境中发展姑息治疗服务的挑战。
IF 5.5 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2023-01-01 DOI: 10.3389/phrs.2023.1605672
Islam Salikhanov, Stephen R Connor, Gulnara Kunirova, Fatima Khashagulgova, Gulzhaina Nazarova, Byron Lawrence Crape, Maria C Katapodi

Background: Approximately 40 million people in need of palliative care worldwide, while 80% of them live in low- and middle-income countries. Kazakhstan, a low-to middle-income country with a reforming healthcare system, is committed to improving quality and accessibility of care for its 100,000 terminal patients in need of palliative care. Policy Options and Recommendations: To join the group of countries where palliative care is available, accessible, and affordable, Kazakhstan must integrate palliative services into the mainstream healthcare system at all levels, from primary healthcare to hospices, and from major cities to remote villages. Based on the evidence thoroughly collected directly from the Ministry of Health, authors propose a feasible set of recommendations regarding palliative policy, pain relief, infrastructure, workforce, and education, which could be implemented in LMICs beyond Kazakhstan. Conclusion: This study presents an analysis of challenges, recent developments, and needs of palliative care in Kazakhstan, including funding, policy, workforce, education, and infrastructure, providing an evidence base and recommendations for future development of palliative care in Kazakhstan and in other LMICs.

背景:全世界约有4000万人需要姑息治疗,其中80%生活在低收入和中等收入国家。哈萨克斯坦是一个医疗体系正在改革的中低收入国家,致力于改善其10万名需要姑息治疗的晚期患者的护理质量和可及性。政策选择和建议:为了加入姑息治疗可获得、可获得和可负担的国家行列,哈萨克斯坦必须将姑息治疗服务纳入各级主流卫生保健系统,从初级卫生保健到临终关怀,从主要城市到偏远村庄。根据直接从卫生部全面收集的证据,作者提出了一套关于姑息政策、疼痛缓解、基础设施、劳动力和教育的可行建议,可在哈萨克斯坦以外的中低收入国家实施。结论:本研究分析了哈萨克斯坦姑息治疗的挑战、最新发展和需求,包括资金、政策、劳动力、教育和基础设施,为哈萨克斯坦和其他中低收入国家姑息治疗的未来发展提供了证据基础和建议。
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引用次数: 0
Frequency of Vitamin a Deficiency in Children Hospitalized for Pneumonia: An Integrative Review. 肺炎住院儿童缺乏维生素 a 的频率:综述。
IF 3.5 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2022-12-13 eCollection Date: 2022-01-01 DOI: 10.3389/phrs.2022.1604500
Amanda De Conceição Leão Mendes, Ana Mayara Gomes De Souza, Aryelly Dayane Da Silva Nunes, Javier Jerez-Roig, Isabelle Ribeiro Barbosa

Objective: To identify the frequency of vitamin A deficiency in children aged 6 months to 5 years hospitalized for pneumonia. Methods: An integrative literature review was carried out, where searches were made by two independent researchers, with no language limits or publication time in the databases PubMed, LILACS, Web of Science, Scopus and CINAHL, and in the gray literature-OpenGrey, Proquest and Google Scholar. In the eligibility phase, the screened studies were read in full and those that did not answer the research question were excluded. Methodological quality was assessed using the Downs & Black (1998) checklist. Results: 1642 articles were identified, after all stages of screening and selection, 10 studies were included, of which 5 were longitudinal, 4 were intervention and 1 transversal. All studies identified subclinical vitamin A deficiency in children hospitalized with pneumonia; the highest frequency of subclinical vitamin A deficiency was 93.2%. All studies evaluated showed frequencies of subclinical vitamin A deficiency >20%. Conclusion: There is a high frequency of subclinical vitamin A deficiency in children with pneumonia; these data need to be further explored in terms of their associations. For this reason, new studies that evaluate this topic are of fundamental importance.

目的确定因肺炎住院的 6 个月至 5 岁儿童缺乏维生素 A 的频率。方法: 由两名独立研究人员进行综合文献综述:由两名独立的研究人员进行综合文献综述,在 PubMed、LILACS、Web of Science、Scopus 和 CINAHL 等数据库以及灰色文献--OpenGrey、Proquest 和 Google Scholar 中进行检索,无语言限制和出版时间限制。在资格审查阶段,对筛选出的研究进行全文阅读,排除那些不能回答研究问题的研究。采用 Downs & Black(1998 年)核对表对研究方法的质量进行评估。结果经过各个阶段的筛选,共确定了 1642 篇文章,其中包括 10 项研究,其中 5 项为纵向研究,4 项为干预研究,1 项为横向研究。所有研究均发现肺炎住院患儿存在亚临床维生素 A 缺乏症;亚临床维生素 A 缺乏症的最高频率为 93.2%。所有评估研究均显示亚临床维生素 A 缺乏症的发生率大于 20%。结论肺炎患儿亚临床维生素 A 缺乏症的发生率很高;这些数据的关联性有待进一步探讨。因此,对这一主题进行评估的新研究至关重要。
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引用次数: 0
Psychosocial Attributes of Housing and Their Relationship With Health Among Refugee and Asylum-Seeking Populations in High-Income Countries: Systematic Review 高收入国家难民和寻求庇护人群住房的社会心理属性及其与健康的关系:系统评价
IF 5.5 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2022-12-05 DOI: 10.1101/2022.12.04.22283020
Tessa Brake, V. Dudek, O. Sauzet, O. Razum
Objectives: Housing as a social determinant of health should provide not only shelter, but also a feeling of home. We explored psychosocial pathways creating a sense of home and influencing the relationship between housing and health among asylum seekers and refugees (ASR) in high-income countries. Methods: We performed a systematic review. To be included, studies had to be peer-reviewed, published between 1995 and 2022, and focus on housing and health of ASR in high-income countries. We conducted a narrative synthesis. Results: 32 studies met the inclusion criteria. The psychosocial attributes influencing health most often identified were control, followed by expressing status, satisfaction, and demand. Most attributes overlap with material/physical attributes and have an impact on ASR’s mental health. They are closely interconnected with each other. Conclusion: Psychosocial attributes of housing play an essential role in the health of ASR; they are closely associated with material/physical attributes. Therefore, future research on housing and health of ASR should routinely study psychosocial attributes, but always in association with physical ones. The connections between these attributes are complex and need to be further explored. Systematic Review Registration: https://www.crd.york.ac.uk/prospero/, identifier CRD42021239495.
目标:住房作为健康的社会决定因素,不仅应提供住所,还应提供家的感觉。我们探索了在高收入国家的寻求庇护者和难民(ASR)中创造家园感并影响住房与健康之间关系的心理社会途径。方法:我们进行了系统回顾。为了纳入研究,必须对1995年至2022年间发表的研究进行同行评审,并重点关注高收入国家ASR的住房和健康。我们进行了一次叙事综合。结果:32项研究符合纳入标准。影响健康最常见的心理社会特征是控制,其次是表达状态、满意度和需求。大多数属性与物质/物理属性重叠,并对ASR的心理健康产生影响。它们彼此紧密相连。结论:住房的心理社会属性对ASR的健康起着至关重要的作用;它们与材料/物理属性密切相关。因此,未来对ASR的住房和健康的研究应该定期研究心理社会属性,但始终与身体属性相关。这些属性之间的联系是复杂的,需要进一步探索。系统评审注册:https://www.crd.york.ac.uk/prospero/,标识符CRD42021239495。
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引用次数: 0
Quality of Cancer Care in Switzerland: Going Beyond Traditional Quality Indicators by Collecting Patient-Reported Experiences of Cancer Care 瑞士癌症护理质量:通过收集癌症护理患者报告经验超越传统质量指标
IF 5.5 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2022-05-17 DOI: 10.3389/phrs.2022.1604813
C. Arditi, I. Peytremann-Bridevaux
Background: High-quality cancer care should be effective, safe, accessible, efficient, equitable, and responsive to patients’ needs. In Switzerland, information on the safety and effectiveness of cancer care is available, but not on responsiveness. Systematic and comprehensive reports from patients on cancer care are missing and needed to complete the assessment of the quality of cancer care. Evidence: Patient-reported experiences of cancer care are key to evaluate responsiveness of care and drive quality improvement initiatives in oncology practice. Studies have found that responsive care leads to more positive experiences of care, which can lead to more effective treatments and health benefits. Policy Options and Recommendations: Our first recommendation is to develop a position statement on the importance and value of patient-reported experiences of cancer care. Our second recommendation is to systematically collect patients’ experiences of cancer care at the national level, through a dedicated national cancer-specific measurement program or through the integration of patient-reported experiences measures in cancer registries. Conclusion: The systematic collection of patient-reported experiences of cancer care provides essential information on what matters to patients in addition to traditional clinical information, including patients as partners of the overall assessment of healthcare performance.
背景:高质量的癌症护理应该是有效的、安全的、可获得的、高效的、公平的,并响应患者的需求。在瑞士,有关于癌症治疗的安全性和有效性的信息,但没有关于反应性的信息。癌症患者的系统和全面的护理报告缺失,需要完成对癌症护理质量的评估。证据:患者报告的癌症治疗经验是评估治疗反应性和推动肿瘤学实践质量改进举措的关键。研究发现,响应性护理会带来更积极的护理体验,从而带来更有效的治疗和健康益处。政策选择和建议:我们的第一个建议是制定一份关于患者报告的癌症治疗经验的重要性和价值的立场声明。我们的第二项建议是通过专门的国家癌症特异性测量计划或通过将患者报告的经验测量纳入癌症登记册,系统地收集患者在国家一级的癌症护理经验。结论:系统收集患者报告的癌症治疗经验,除了传统的临床信息外,还提供了对患者重要的信息,包括患者作为医疗绩效总体评估的合作伙伴。
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引用次数: 0
Exploring Cross-Sectoral Implications of the Sustainable Development Goals: Towards a Framework for Integrating Health Equity Perspectives With the Land-Water-Energy Nexus 探索可持续发展目标的跨部门影响:建立一个将卫生公平观点与土地-水-能源关系结合起来的框架
IF 5.5 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2022-05-11 DOI: 10.3389/phrs.2022.1604362
C. O. Onabola, N. Andrews, M. Gislason, H. Harder, M. Parkes
Objectives: To assess existing evidence and identify gaps in the integrative framework of the Sustainable Development Goals (SDGs) for their potential to advance cross-sectoral perspectives and actions that connect health equity with the land-water-energy nexus in a watershed context. Methods: Five bibliographic databases were searched from 2016 to 2021. This yielded an initial 226 publications, which were screened for titles, abstracts, and full texts on DistillerSR; resulting in a final 30 publications that were studied. These keywords defined the search terms: “health equity,” “SDGs,” “watershed,” “resource nexus,” and “cross-sectoral.” Results: Thematic syntheses of debates and gaps point to the relevance of the SDGs as a cross-sectoral, integrative platform for place-based programming of the land-water-energy nexus, and to account for negative externalities and cascaded impacts on human and environmental health. Conclusion: For the purpose of monitoring health equity in the contexts of interactions of land, water, and energy in rural, remote, and Indigenous contexts, and on the basis of the SDGs, this paper generates evidence to inform health equity-oriented policies, programs and practices, and to enhance health for equity-seeking populations.
目标:评估现有证据并确定可持续发展目标综合框架中的差距,以确定其在促进跨部门观点和行动方面的潜力,从而在流域背景下将卫生公平与土地-水-能源关系联系起来。方法:检索2016 - 2021年5个文献数据库。这产生了最初的226篇出版物,这些出版物在DistillerSR上进行了标题、摘要和全文筛选;最后的30份出版物被研究。这些关键词定义了搜索词:“卫生公平”、“可持续发展目标”、“分水岭”、“资源联系”和“跨部门”。结果:对辩论和差距的专题综合表明,可持续发展目标是一个跨部门的综合平台,可以根据地点规划土地-水-能源关系,并考虑到负面外部性和对人类和环境健康的级联影响。结论:为了监测农村、偏远地区和土著地区土地、水和能源相互作用背景下的卫生公平,并在可持续发展目标的基础上,本文为卫生公平导向的政策、项目和实践提供证据,并增强寻求公平人群的健康。
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引用次数: 1
Occupational Factors Affecting Women Workers' Sexual and Reproductive Health Outcomes in Oil, Gas, and Mining Industry: A Scoping Review. 影响石油、天然气和采矿业女工性健康和生殖健康结果的职业因素:范围审查
IF 3.5 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2022-04-28 eCollection Date: 2022-01-01 DOI: 10.3389/phrs.2022.1604653
Rina Hariniaina Razafimahefa, Jerico Franciscus Pardosi, Adem Sav

Objectives: Globally, female workers workforce in Oil, Gas, and Mining (OGM) industry have increased significantly. The complexities of the OGM operations and the extensive exposure to workplace hazards potentially affect the health status of workers, including sexual and reproductive health (SRH) outcomes of female workers. Yet, the current state of knowledge on SRH issues in OGM contexts seems to be limited and fragmented. This scoping review aims to identify the occupational factors that influence women's SRH outcomes in OGM industry. Methods: This scoping review followed the Joanna Briggs Institute's guidelines (PRISMA) and was conducted in five databases, including the citation chaining via Google Scholar and manual search through relevant organisations and Government websites. Sixteen articles met the inclusion criteria and were analysed. Results: Despite the scarcity of evidence, chemical and physical are found to be the predominant factors greatly influencing women workers' SRH outcomes in OGM. Most studies showed menstrual and cycle disorders, and risky pregnancy as key SRH issues. However, menstruation disorder was considerably linked with psychological and organisational factors. Conclusion: This review suggests further empirical research on the relationship between OGM occupational hazards and women workers' SRH. This will contribute to improvements in workplace safety legislations, measures, policies, and management systems taking into account women's needs.

目标:在全球范围内,石油、天然气和采矿业的女性劳动力大幅增加。OGM操作的复杂性和广泛暴露于工作场所的危险可能会影响工人的健康状况,包括女性工人的性健康和生殖健康(SRH)结果。然而,OGM背景下关于性健康和生殖健康问题的知识现状似乎是有限和零散的。本范围审查旨在确定影响OGM行业女性SRH结果的职业因素。方法:这项范围界定审查遵循了乔安娜·布里格斯研究所的指南(PRISMA),在五个数据库中进行,包括通过谷歌学者的引文链接和通过相关组织和政府网站的手动搜索。16篇文章符合纳入标准并进行了分析。结果:尽管缺乏证据,但化学和物理因素是影响OGM女工SRH结果的主要因素。大多数研究表明,月经和周期紊乱以及危险妊娠是SRH的关键问题。然而,月经失调在很大程度上与心理和组织因素有关。结论:本综述建议进一步实证研究OGM职业危害与女工SRH的关系。这将有助于改进考虑到妇女需求的工作场所安全立法、措施、政策和管理系统。
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引用次数: 0
Situating Health Within the 2030 Agenda—A Practical Application of the Sustainable Development Goals Synergies Approach 将健康纳入2030年议程——可持续发展目标协同方法的实际应用
IF 5.5 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2022-04-07 DOI: 10.3389/phrs.2022.1604350
D. Helldén, Nina Weitz, M. Nilsson, T. Alfvén
Background: The Sustainable Development Goals (SDGs) are integrated, indivisible and interdependent and interact and affect each other directly and indirectly. However, the 2030 Agenda does not attempt to identify or characterise these interactions. Evidence: The SDG Synergies approach was developed to enable the investigation of the strength and nature of interactions between SDGs based on the perception of a multistakeholder group. Two examples are given to concretely demonstrate how this approach overcomes present challenges and can be applied to situate health within the 2030 Agenda. Policy Options and Recommendations: There are clear benefits to situate desired health policy outcomes within the 2030 Agenda, and the SDG Synergies approach can be used as lever for including health aspects in traditional non-health sectors. Although focusing on specific health policies cannot be substituted with multisectoral policies alone, utilizing tools and methods such as the SDG Synergies approach can help policy makers put health at the centre of the SDGs. Conclusion: SDG Synergies is an impactful approach for policy makers to gain a systemic understanding of how broader sustainable development shape the health and well-being of people and vice versa.
背景:可持续发展目标是整体的、不可分割的、相互依存的,相互作用,直接或间接地相互影响。然而,《2030年议程》并未试图确定或描述这些相互作用。证据:制定了可持续发展目标协同效应方法,以便根据多利益相关方群体的看法,调查可持续发展目标之间相互作用的强度和性质。文中给出了两个例子,具体说明这一办法如何克服目前的挑战,并可用于将卫生问题置于《2030年议程》的框架内。政策选择和建议:将期望的卫生政策成果置于《2030年议程》中有明显的好处,可持续发展目标协同效应方法可作为杠杆,将卫生方面纳入传统的非卫生部门。虽然专注于具体卫生政策不能被单独的多部门政策所取代,但利用可持续发展目标协同增效办法等工具和方法可以帮助决策者将卫生置于可持续发展目标的中心。结论:可持续发展目标协同效应是政策制定者系统了解更广泛的可持续发展如何影响人民健康和福祉的有效方法,反之亦然。
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引用次数: 4
Methods Matter: A Comparative Review of Health Risk Assessments for Ambient Air Pollution in Switzerland 方法很重要:瑞士环境空气污染健康风险评估的比较综述
IF 5.5 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2022-04-06 DOI: 10.3389/phrs.2022.1604431
A. Castro, M. Röösli, K. de Hoogh, R. Kappeler, M. Kutlar Joss, D. Vienneau, N. Künzli
Objectives: Air pollution health risk assessments (AP-HRAs) provide a method to quantify health effects for entire populations. In Switzerland, AP-HRAs are included in Swiss assessments for Transport Externalities (STEs), ordered by public authorities since the 1990s. This study aimed to describe the differences among national and international AP-HRAs for Switzerland. Methods: We compared input data, approaches and results across AP-HRAs over time. Results and input data for each AP-HRA were expressed as a ratio compared to the most recent STE (in most cases STE-2010). Results: Substantial variation across AP-HRAs was found. For all-cause adult mortality attributed to particulate matter (the most frequent outcome-pollutant pair), the ratio in HRAs oscillated from 0.40 to 2.09 (times the STE-2010 value). Regarding input data, the ratio ranged from 0.69 to 1.26 for population exposure, from 0 to 1.81 for counterfactual scenario, from 0.96 to 1.13 for concentration-response function and from 1.03 to 1.13 for baseline health data. Conclusion: This study demonstrates that methods matter for AP-HRAs. Transparent and possibly standardized reporting of key input data and assumptions should be promoted to facilitate comparison of AP-HRAs. Graphical Abstract
目的:空气污染健康风险评估(AP HRA)为量化整个人群的健康影响提供了一种方法。在瑞士,自20世纪90年代以来,公共当局下令将AP HRA纳入瑞士交通外部性评估(STE)。本研究旨在描述瑞士国内和国际AP HRA之间的差异。方法:我们比较了一段时间以来AP HRA的输入数据、方法和结果。每个AP-HRA的结果和输入数据表示为与最近的STE(在大多数情况下为STE-2010)相比的比率。结果:AP HRA之间存在显著差异。对于归因于颗粒物(最常见的结果污染物对)的全因成人死亡率,HRA的比率在0.40到2.09之间波动(STE-2010值的倍)。关于输入数据,人群暴露的比率为0.69至1.26,反事实情景的比率为0至1.81,浓度反应函数的比率为0.96至1.13,基线健康数据的比率为1.03至1.13。结论:本研究表明,方法对AP HRA很重要。应促进对关键输入数据和假设进行透明且可能标准化的报告,以便于对AP HRA进行比较。图形摘要
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引用次数: 3
The Role of Europe’s Schools of Public Health in Times of War: ASPHER Statement on the War Against Ukraine 欧洲公共卫生学院在战争时期的作用:ASPHER关于乌克兰战争的声明
IF 5.5 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2022-03-16 DOI: 10.3389/phrs.2022.1604880
L. Wandschneider, Y. Namer, N. Davidovitch, D. Nitzan, R. Otok, L. Leighton, C. Signorelli, J. Middleton, J. Martin-Moreno, L. Chambaud, Henrique Lopes, O. Razum
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引用次数: 7
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