首页 > 最新文献

Anestezi Dergisi最新文献

英文 中文
The Effect of Spinal and General Anesthesia on Thiol-Disulfide Balance During Ischemia/Reperfusion of the Leg in Patients Undergoing Knee Replacement Surgery 腰麻和全麻对膝关节置换术患者腿部缺血/再灌注时巯基二硫化物平衡的影响
Q4 Medicine Pub Date : 2023-07-31 DOI: 10.54875/jarss.2023.35492
E. M. Şimşek, Ş. M. Aksoy, Nurettin Nurettin Manti, O. Erel, S. Neşelioğlu, A. Fırat
Objective: Surgical trauma causes serious neuroendocrine and cytokine activity. In addition, the free oxygen radicals formed because of the ischemia/reperfusion injury resulting from applying and releasing the tourniquet (TQ) cause oxidative stress. Thiol and disulfide are among the new oxidative stress parameters used reliably in recent years. The aim of this study was to compare thiol-disulfide balance in general and spinal anesthesia, which are frequently used in total knee replacement (TKR) surgery. Methods: Fifty six patients aged 60-74 years scheduled to undergo TKR were randomly allocated to the general anesthesia (n=26) and spinal anesthesia (n=30) groups. The tourniquet (TQ) was applied for the TKR procedure after collecting a preanesthetic blood sample (T1). Blood samples were also collected at 5 minutes (T2) and 40 minutes (T3) after TQ release and at postoperative 24 hours (T4) to analyze native thiol, total thiol, disulfide, disulfide/native thiol ratio, disulfide/total thiol ratio, and native thiol/total thiol ratio. All patients had intravenous patient-controlled analgesia during the postoperative period. Mean arterial pressure, TQ times, and Visual Analogue Scale (VAS) scores were recorded. Decrease in thiol and increase in disulfide in the thiol-disulfide balance were recorded as oxidative stress indicators. Results: There was no difference between the groups in terms of VAS and analgesic consumption at the end of 24 hours. The general anesthesia group had higher native thiol, total thiol, and native thiol/total thiol ratio and lower disulfide, disulfide/native thiol ratio, and disulfide/total thiol ratio at all time points compared to the spinal anesthesia group. Conclusion: Assessment in terms of thiol-disulfide balance suggests that general anesthesia had a favorable effect on oxidative stress. Keywords: General anesthesia, oxidative stress, spinal anesthesia, thiol-disulfide, tourniquet time, visual analogue scale
目的:外科创伤引起严重的神经内分泌和细胞因子活性。此外,由于应用和释放止血带(TQ)引起的缺血/再灌注损伤而形成的自由氧自由基会引起氧化应激。硫醇和二硫化物是近年来可靠使用的新的氧化应激参数之一。本研究的目的是比较全膝关节置换术(TKR)手术中常用的全身麻醉和脊髓麻醉中的硫醇-二硫化物平衡。方法:将56例年龄在60-74岁的TKR患者随机分为全麻组(n=26)和脊麻组(n=30)。在采集人工前血样(T1)后,将止血带(TQ)用于TKR手术。还在TQ释放后5分钟(T2)和40分钟(T3)以及术后24小时(T4)采集血样,以分析天然硫醇、总硫醇、二硫化物、二硫化物/天然硫醇比、二硫化物-总硫醇比和天然硫醇/总硫醇比。所有患者术后均采用静脉自控镇痛。记录平均动脉压、TQ时间和视觉模拟量表(VAS)评分。硫醇-二硫化物平衡中硫醇的减少和二硫化物的增加被记录为氧化应激指标。结果:两组在VAS和24小时结束时的镇痛消耗方面没有差异。与脊麻组相比,全麻组在所有时间点的天然硫醇、总硫醇和天然硫醇/总硫醇比率较高,二硫化物、二硫化物/天然硫醇比率和二硫化物/总硫醇比例较低。结论:根据硫醇-二硫化物平衡的评估表明,全身麻醉对氧化应激有良好的影响。关键词:全身麻醉、氧化应激、脊髓麻醉、二硫硫醇、止血带时间、视觉模拟量表
{"title":"The Effect of Spinal and General Anesthesia on Thiol-Disulfide Balance During Ischemia/Reperfusion of the Leg in Patients Undergoing Knee Replacement Surgery","authors":"E. M. Şimşek, Ş. M. Aksoy, Nurettin Nurettin Manti, O. Erel, S. Neşelioğlu, A. Fırat","doi":"10.54875/jarss.2023.35492","DOIUrl":"https://doi.org/10.54875/jarss.2023.35492","url":null,"abstract":"Objective: Surgical trauma causes serious neuroendocrine and cytokine activity. In addition, the free oxygen radicals formed because of the ischemia/reperfusion injury resulting from applying and releasing the tourniquet (TQ) cause oxidative stress. Thiol and disulfide are among the new oxidative stress parameters used reliably in recent years. The aim of this study was to compare thiol-disulfide balance in general and spinal anesthesia, which are frequently used in total knee replacement (TKR) surgery. Methods: Fifty six patients aged 60-74 years scheduled to undergo TKR were randomly allocated to the general anesthesia (n=26) and spinal anesthesia (n=30) groups. The tourniquet (TQ) was applied for the TKR procedure after collecting a preanesthetic blood sample (T1). Blood samples were also collected at 5 minutes (T2) and 40 minutes (T3) after TQ release and at postoperative 24 hours (T4) to analyze native thiol, total thiol, disulfide, disulfide/native thiol ratio, disulfide/total thiol ratio, and native thiol/total thiol ratio. All patients had intravenous patient-controlled analgesia during the postoperative period. Mean arterial pressure, TQ times, and Visual Analogue Scale (VAS) scores were recorded. Decrease in thiol and increase in disulfide in the thiol-disulfide balance were recorded as oxidative stress indicators. Results: There was no difference between the groups in terms of VAS and analgesic consumption at the end of 24 hours. The general anesthesia group had higher native thiol, total thiol, and native thiol/total thiol ratio and lower disulfide, disulfide/native thiol ratio, and disulfide/total thiol ratio at all time points compared to the spinal anesthesia group. Conclusion: Assessment in terms of thiol-disulfide balance suggests that general anesthesia had a favorable effect on oxidative stress. Keywords: General anesthesia, oxidative stress, spinal anesthesia, thiol-disulfide, tourniquet time, visual analogue scale","PeriodicalId":36000,"journal":{"name":"Anestezi Dergisi","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45629433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Septoplasti Operasyonlarında Ketofol ile Midazolam-Fentanil Sedoanaljezi Yöntemlerinin Karşılaştırılması
Q4 Medicine Pub Date : 2023-07-31 DOI: 10.54875/jarss.2023.35693
Bilge Olgun Keleş, M. Kaya, Serpil Şavlı, Fatih Arslan, Cemile Açıkgöz Yıldız, Elvan Tekir Yılmaz
Objective: Sedoanalgesia is an anesthesia method that is preferred mostly in outside the operating room interventions and some short-term surgeries, allowing the procedure to be performed by using sedative and dissociative agents alone or together. Closed technique septoplasty operation is also an operation that can be performed with sedoanalgesia. The aim of this study is to compare the sedative and analgesic effects of ketamine and propofol combination and midazolam and fentanyl combination, surgical satisfaction and patient satisfaction in patients who underwent closed technique septoplasty operation. Methods: After ethics committee approval, 60 ASA I and II patients were included in the study by dividing into 2 groups. Patients who used ketamine and propofol for sedoanalgesia were named Group 1 (ketofol), and patients who used midazolam and fentanyl were named Group 2 (midafenta). The data of the patients were recorded from the intraoperative anesthesia forms and the postoperative recovery unit forms. Complications, side effects, surgery and patient satisfaction were questioned. Results: Mean arterial pressure was found to be significantly lower in the ketofol group at the 3rd minute after induction than in the midfenta group. The sedation score in the midafenta group at the 10th and 20th minutes intraoperatively was significantly lower than in the ketofol group. There was no significant difference in patient satisfaction, but surgical satisfaction was significantly higher in the midafenta group. Conclusion: In closed technique septoplasty operations, sedoanalgesia applied with ketofol and midafenta methods can be used without the need for general anesthesia. However, ketofol, which is highly preferred for sedoanalgesia, did not provide sufficient surgical satisfaction in patients who underwent closed technique septoplasty. We attributed this to the dissociation of the patients and their inability to comply with surgical commands. Keywords: Propofol, ketamine, midazolam, fentanyl
目的:镇静镇痛是一种麻醉方法,主要用于手术室外干预和一些短期手术,允许单独或联合使用镇静剂和离解剂进行手术。闭式技术鼻中隔成形术也是一种可用于硬膜外疼痛的手术。本研究的目的是比较氯胺酮和丙泊酚联合用药以及咪达唑仑和芬太尼联合用药的镇静镇痛效果、手术满意度和患者满意度。方法:经伦理委员会批准,将60名ASA I和II患者分为2组纳入研究。使用氯胺酮和丙泊酚治疗坐痛的患者被命名为第1组(酮醇),使用咪达唑仑和芬太尼的患者被称为第2组(米达芬塔)。患者的数据记录在术中麻醉表格和术后恢复单位表格中。并发症、副作用、手术和患者满意度受到质疑。结果:酮醇组在诱导后第3分钟的平均动脉压显著低于足中部组。术中第10分钟和第20分钟,米达芬塔组的镇静评分显著低于酮醇组。患者满意度没有显著差异,但米达芬塔组的手术满意度明显更高。结论:在封闭式鼻中隔成形术中,应用酮醇和米达芬塔方法可以在不需要全身麻醉的情况下使用镇静镇痛。然而,酮症酸中毒是首选药物,但在接受封闭式鼻中隔成形术的患者中,酮症醇并不能提供足够的手术满意度。我们将此归因于患者的分离以及他们无法遵守手术指令。关键词:异丙酚、氯胺酮、咪唑安定、芬太尼
{"title":"Septoplasti Operasyonlarında Ketofol ile Midazolam-Fentanil Sedoanaljezi Yöntemlerinin Karşılaştırılması","authors":"Bilge Olgun Keleş, M. Kaya, Serpil Şavlı, Fatih Arslan, Cemile Açıkgöz Yıldız, Elvan Tekir Yılmaz","doi":"10.54875/jarss.2023.35693","DOIUrl":"https://doi.org/10.54875/jarss.2023.35693","url":null,"abstract":"Objective: Sedoanalgesia is an anesthesia method that is preferred mostly in outside the operating room interventions and some short-term surgeries, allowing the procedure to be performed by using sedative and dissociative agents alone or together. Closed technique septoplasty operation is also an operation that can be performed with sedoanalgesia. The aim of this study is to compare the sedative and analgesic effects of ketamine and propofol combination and midazolam and fentanyl combination, surgical satisfaction and patient satisfaction in patients who underwent closed technique septoplasty operation. Methods: After ethics committee approval, 60 ASA I and II patients were included in the study by dividing into 2 groups. Patients who used ketamine and propofol for sedoanalgesia were named Group 1 (ketofol), and patients who used midazolam and fentanyl were named Group 2 (midafenta). The data of the patients were recorded from the intraoperative anesthesia forms and the postoperative recovery unit forms. Complications, side effects, surgery and patient satisfaction were questioned. Results: Mean arterial pressure was found to be significantly lower in the ketofol group at the 3rd minute after induction than in the midfenta group. The sedation score in the midafenta group at the 10th and 20th minutes intraoperatively was significantly lower than in the ketofol group. There was no significant difference in patient satisfaction, but surgical satisfaction was significantly higher in the midafenta group. Conclusion: In closed technique septoplasty operations, sedoanalgesia applied with ketofol and midafenta methods can be used without the need for general anesthesia. However, ketofol, which is highly preferred for sedoanalgesia, did not provide sufficient surgical satisfaction in patients who underwent closed technique septoplasty. We attributed this to the dissociation of the patients and their inability to comply with surgical commands. Keywords: Propofol, ketamine, midazolam, fentanyl","PeriodicalId":36000,"journal":{"name":"Anestezi Dergisi","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42242065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Laparoscopic Surgery and Anesthesia 腹腔镜手术与麻醉
Q4 Medicine Pub Date : 2023-07-31 DOI: 10.54875/jarss.2023.63496
B. Gokdemir, N. Çekmen
Laparoscopic surgery (LS) is superior to conventional laparotomy due to its advantages, such as less trauma, early mobilization, minimal blood loss, less scarring, reduced postoperative pain, shorter postoperative recovery time and hospital stay, and lower mortality and morbidity. Significant hemodynamic, cardiopulmonary, and physiological changes occur in the systems due to increased intra-abdominal pressure and hypercarbia after carbon dioxide insufflation is applied for pneumoperitoneum (PP) during LS. The main goals in anesthesia management are understanding the primary pathophysiology, optimizing functional status and hemodynamics, and managing comorbidities. To minimize the effects and impacts of PP in patients who will undergo LS, as in every patient, comprehensive preoperative evaluation should be carried out by multidisciplinary approach that includes an anesthesiologist and surgeon. Our review emphasizes the importance of pathophysiological and systemic changes during LS performed by applying PP and summarizes the recovery and postoperative complications of anesthesia methods applied in clinical practice. Keywords: Laparoscopic surgeries, pneumoperitoneum, hemodynamic and cardiopulmonary changes, anesthesia
腹腔镜手术(LS)具有创伤小、活动早、出血量少、疤痕少、术后疼痛减轻、术后恢复时间短、住院时间短、死亡率和发病率低等优点,优于传统的剖腹手术。在LS期间对气腹(PP)进行二氧化碳充气后,由于腹内压力增加和高碳血症,系统会发生显著的血流动力学、心肺和生理变化。麻醉管理的主要目标是了解主要病理生理,优化功能状态和血流动力学,并管理合并症。为了尽量减少PP对LS患者的影响,就像对每个患者一样,应该通过包括麻醉师和外科医生在内的多学科方法进行全面的术前评估。我们的综述强调了应用PP进行LS时病理生理和全身变化的重要性,并总结了临床应用的麻醉方法的恢复和术后并发症。关键词:腹腔镜手术,气腹,血流动力学和心肺改变,麻醉
{"title":"Laparoscopic Surgery and Anesthesia","authors":"B. Gokdemir, N. Çekmen","doi":"10.54875/jarss.2023.63496","DOIUrl":"https://doi.org/10.54875/jarss.2023.63496","url":null,"abstract":"Laparoscopic surgery (LS) is superior to conventional laparotomy due to its advantages, such as less trauma, early mobilization, minimal blood loss, less scarring, reduced postoperative pain, shorter postoperative recovery time and hospital stay, and lower mortality and morbidity. Significant hemodynamic, cardiopulmonary, and physiological changes occur in the systems due to increased intra-abdominal pressure and hypercarbia after carbon dioxide insufflation is applied for pneumoperitoneum (PP) during LS. The main goals in anesthesia management are understanding the primary pathophysiology, optimizing functional status and hemodynamics, and managing comorbidities. To minimize the effects and impacts of PP in patients who will undergo LS, as in every patient, comprehensive preoperative evaluation should be carried out by multidisciplinary approach that includes an anesthesiologist and surgeon. Our review emphasizes the importance of pathophysiological and systemic changes during LS performed by applying PP and summarizes the recovery and postoperative complications of anesthesia methods applied in clinical practice. Keywords: Laparoscopic surgeries, pneumoperitoneum, hemodynamic and cardiopulmonary changes, anesthesia","PeriodicalId":36000,"journal":{"name":"Anestezi Dergisi","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42287167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ağır Valproik Asit Zehirlenmesinde Kombine Tedavi 丙戊酸中毒指挥治疗
Q4 Medicine Pub Date : 2023-07-31 DOI: 10.54875/jarss.2023.21704
Fatma Erseven
Valproic acid is frequently given to individuals who suffer from a variety of psychological and neurological conditions, including bipolar disorder, manic-depressive psychosis, major depressive disorder, post-traumatic stress disorder, and epilepsy. Because of its narrow therapeutic spectrum, it is one of agents that frequently cause toxicological emergencies. This case presents an adult patient who had valproic acid overdose, required intubation, hemodialysis, and concurrent treatment with carbapenem group antibiotics. Keywords: Valproic acid, intoxication, hemodialysis, carbapenem
丙戊酸经常被给予患有各种心理和神经疾病的个体,包括双相情感障碍、躁狂抑郁精神病、重度抑郁症、创伤后应激障碍和癫痫。由于其治疗范围窄,是经常引起毒理学紧急事件的药物之一。本病例是一位丙戊酸过量的成人患者,需要插管,血液透析,同时使用碳青霉烯类抗生素治疗。关键词:丙戊酸;中毒;血液透析
{"title":"Ağır Valproik Asit Zehirlenmesinde Kombine Tedavi","authors":"Fatma Erseven","doi":"10.54875/jarss.2023.21704","DOIUrl":"https://doi.org/10.54875/jarss.2023.21704","url":null,"abstract":"Valproic acid is frequently given to individuals who suffer from a variety of psychological and neurological conditions, including bipolar disorder, manic-depressive psychosis, major depressive disorder, post-traumatic stress disorder, and epilepsy. Because of its narrow therapeutic spectrum, it is one of agents that frequently cause toxicological emergencies. This case presents an adult patient who had valproic acid overdose, required intubation, hemodialysis, and concurrent treatment with carbapenem group antibiotics. Keywords: Valproic acid, intoxication, hemodialysis, carbapenem","PeriodicalId":36000,"journal":{"name":"Anestezi Dergisi","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48438584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Yoğun Bakımdaki COVID-19 Hastalarında Prognostik Belirteçler: Hemostatik Parametreler Mortaliteyi Öngörebilir mi? 西开普省新冠肺炎患者的预后体征:止血参数能预测死亡率吗?
Q4 Medicine Pub Date : 2023-07-31 DOI: 10.54875/jarss.2023.55822
Duygu Kayar Çalılı, Ali Yasin Özercan, Halil Demirçakan, S. Ünal, Serdar Başboğa, Y. Aslan, D. Erdem, Demet Bölükbaşı, Seval Izdeş
Objective: Our study aimed to investigate whether primarily hemostasis parameters and secondarily demographic, clinical, and laboratory values could predict the mortality of critically ill Coronavirus Disease 2019 (COVID-19) patients. Methods: We retrospectively examined 180 laboratory-confirmed adult intensive care unit (ICU) patients with COVID-19. A total of 145 patients with complete records were included in the study. The patients were divided into two groups: deceased (n=58) and discharged (n=87). The demographic and clinical characteristics of the two groups, use of vasopressor therapy, requirement for invasive mechanical ventilation (IMV), Acute Physiology and Chronic Health Evaluation II (APACHE II) score, duration of ICU stay, and the relationship between laboratory values on ICU admission and mortality were evaluated using cutoff values. Results: Among hemostatic parameters, only D-dimer>1.08 mg L-1 was found to be a significant predictor of mortality (p=0.04), while platelet, prothrombin time (PT), activated partial thromboplastin time (aPTT), International Normalized Ratio (INR) and fibrinogen values were not significantly associated with mortality (p>0.05). In addition, age >76 years, hypertension (HT), need for IMV, APACHE II score >23, procalcitonin (PCT) >0.21 μg L-1, lymphocytes <0.4 109 L-1, interleukin 6 (IL-6) >93 pg mL-1 were found to be predictors of mortality (p<0.05). Neutrophil and C-reactive protein (CRP) values were not significantly associated with mortality (p>0.05). ABSTRACT Conclusion: Our study determined that advanced age, HT, high APACHE II score, requirement for IMV, vasopressor therapy, PCT, lymphocyte count, IL-6, and D-dimer levels could serve as predictors of mortality. Identifying predictors of mortality in COVID-19 is valuable for early recognition of disease progression and management of potential complications. Keywords: COVID-19, mortality, hemostasis, clinical markers, laboratory markers
目的:本研究旨在探讨主要止血参数和次要的人口学、临床和实验室值是否可以预测2019冠状病毒病(COVID-19)危重症患者的死亡率。方法:回顾性分析180例实验室确诊的成人重症监护病房(ICU) COVID-19患者。共有145名记录完整的患者被纳入研究。患者分为两组:死亡58例和出院87例。采用截断值评估两组患者的人口学和临床特征、血管加压治疗的使用情况、有创机械通气(IMV)的需求、急性生理和慢性健康评估II (APACHE II)评分、ICU住院时间以及ICU入院的实验室值与死亡率之间的关系。结果:在止血参数中,只有d -二聚体>1.08 mg L-1与死亡率有显著相关性(p=0.04),而血小板、凝血酶原时间(PT)、活化的部分凝血活素时间(aPTT)、国际标准化比值(INR)和纤维蛋白原值与死亡率无显著相关性(p>0.05)。此外,年龄bb0 ~ 76岁、高血压(HT)、IMV需用、APACHEⅱ评分>23、降钙素原(PCT) >0.21 μg -1、淋巴细胞93 pg mL-1是死亡率的预测因素(p0.05)。结论:我们的研究确定高龄、HT、高APACHE II评分、IMV需求、血管加压治疗、PCT、淋巴细胞计数、IL-6和d -二聚体水平可以作为死亡率的预测因子。确定COVID-19的死亡率预测因素对于早期识别疾病进展和管理潜在并发症具有重要意义。关键词:COVID-19,死亡率,止血,临床指标,实验室指标
{"title":"Yoğun Bakımdaki COVID-19 Hastalarında Prognostik Belirteçler: Hemostatik Parametreler Mortaliteyi Öngörebilir mi?","authors":"Duygu Kayar Çalılı, Ali Yasin Özercan, Halil Demirçakan, S. Ünal, Serdar Başboğa, Y. Aslan, D. Erdem, Demet Bölükbaşı, Seval Izdeş","doi":"10.54875/jarss.2023.55822","DOIUrl":"https://doi.org/10.54875/jarss.2023.55822","url":null,"abstract":"Objective: Our study aimed to investigate whether primarily hemostasis parameters and secondarily demographic, clinical, and laboratory values could predict the mortality of critically ill Coronavirus Disease 2019 (COVID-19) patients. Methods: We retrospectively examined 180 laboratory-confirmed adult intensive care unit (ICU) patients with COVID-19. A total of 145 patients with complete records were included in the study. The patients were divided into two groups: deceased (n=58) and discharged (n=87). The demographic and clinical characteristics of the two groups, use of vasopressor therapy, requirement for invasive mechanical ventilation (IMV), Acute Physiology and Chronic Health Evaluation II (APACHE II) score, duration of ICU stay, and the relationship between laboratory values on ICU admission and mortality were evaluated using cutoff values. Results: Among hemostatic parameters, only D-dimer>1.08 mg L-1 was found to be a significant predictor of mortality (p=0.04), while platelet, prothrombin time (PT), activated partial thromboplastin time (aPTT), International Normalized Ratio (INR) and fibrinogen values were not significantly associated with mortality (p>0.05). In addition, age >76 years, hypertension (HT), need for IMV, APACHE II score >23, procalcitonin (PCT) >0.21 μg L-1, lymphocytes <0.4 109 L-1, interleukin 6 (IL-6) >93 pg mL-1 were found to be predictors of mortality (p<0.05). Neutrophil and C-reactive protein (CRP) values were not significantly associated with mortality (p>0.05). ABSTRACT Conclusion: Our study determined that advanced age, HT, high APACHE II score, requirement for IMV, vasopressor therapy, PCT, lymphocyte count, IL-6, and D-dimer levels could serve as predictors of mortality. Identifying predictors of mortality in COVID-19 is valuable for early recognition of disease progression and management of potential complications. Keywords: COVID-19, mortality, hemostasis, clinical markers, laboratory markers","PeriodicalId":36000,"journal":{"name":"Anestezi Dergisi","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47207559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Successful Anesthesia Management in Patient with Massive Arterial Air Embolism During Cardiac Surgery 心脏手术中大量动脉空气栓塞患者的成功麻醉处理
Q4 Medicine Pub Date : 2023-04-28 DOI: 10.54875/jarss.2023.40327
Nadide Örs Yıldırım, A. K. Yıldırım, V. Yıldırım
Massive arterial gas embolism is a complication that has a low probability of occurring during cardiac surgery but can cause high mortality and morbidity. It is very important that the surgical, anesthetic, and perfusion teams cooperate in the management of massive gas embolisms. In this article, we discuss the successful management of a massive air embolism that occurred during cardiopulmonary bypass. The patient was discharged from the hospital without complications on the 7th postoperative day. The article emphasizes the importance of a careful anesthesiologist monitoring the surgical field during surgery. Keywords: Massive arterial air embolism, cardiac surgery, neuroprotection
大量动脉气体栓塞是心脏手术中发生的一种低概率并发症,但可导致高死亡率和发病率。外科、麻醉和灌注团队在处理大量气体栓塞时的合作是非常重要的。在这篇文章中,我们讨论了在体外循环过程中发生的大面积空气栓塞的成功处理。患者于术后第7天无并发症出院。本文强调了在手术过程中,一位细心的麻醉师监测手术野的重要性。关键词:大动脉空气栓塞,心脏外科,神经保护
{"title":"A Successful Anesthesia Management in Patient with Massive Arterial Air Embolism During Cardiac Surgery","authors":"Nadide Örs Yıldırım, A. K. Yıldırım, V. Yıldırım","doi":"10.54875/jarss.2023.40327","DOIUrl":"https://doi.org/10.54875/jarss.2023.40327","url":null,"abstract":"Massive arterial gas embolism is a complication that has a low probability of occurring during cardiac surgery but can cause high mortality and morbidity. It is very important that the surgical, anesthetic, and perfusion teams cooperate in the management of massive gas embolisms. In this article, we discuss the successful management of a massive air embolism that occurred during cardiopulmonary bypass. The patient was discharged from the hospital without complications on the 7th postoperative day. The article emphasizes the importance of a careful anesthesiologist monitoring the surgical field during surgery. Keywords: Massive arterial air embolism, cardiac surgery, neuroprotection","PeriodicalId":36000,"journal":{"name":"Anestezi Dergisi","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46340908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Chemotherapy-Induced Peripheral Neuropathy and Treatment 化疗引起的周围神经病变及其治疗
Q4 Medicine Pub Date : 2023-04-28 DOI: 10.54875/jarss.2023.06977
Okan Ermiş, D. Akçalı
ABSTRACT Chemotherapy induced peripheral neuropathy is a syndrome with distal symmetrical sensorial-dominant pain, tingling and numbness caused by neurotoxic chemotherapeutic agents. The severity increases with cumulative doses of chemotherapy, besides decrease in quality of life, may lead to cessation of treatment which may effect survival. Neurotoxicity causes large fiber and small fiber neuropathy through many pathologic mechanisms including mitochondrial dysfunction and oxidative stress. Dose related neuropathic pain is most commonly seen with taxanes, platins, vinca alkaloids, bortezomib and brentuximab. There is a limited effect of anticonvulsant and antidepressant medication for treatment. In this review awareness about chemotherapy induced peripheral neuropathy, prevention and treatment are discussed. Keywords: Chemotherapy, pain, neuropathy, small fiber neuropathy
摘要化疗诱导的周围神经病变是一种由神经毒性化疗药物引起的以远端对称性感觉为主的疼痛、刺痛和麻木的综合征。严重程度随着化疗的累积剂量而增加,除了生活质量下降外,还可能导致治疗停止,从而影响生存率。神经毒性通过许多病理机制引起大纤维和小纤维神经病,包括线粒体功能障碍和氧化应激。剂量相关的神经性疼痛最常见于紫杉烷、铂、长春花生物碱、硼替佐米和布伦妥昔单抗。抗惊厥和抗抑郁药物的治疗效果有限。在这篇综述中,对化疗诱导的周围神经病变的认识、预防和治疗进行了讨论。关键词:化疗、疼痛、神经病变、小纤维神经病变
{"title":"Chemotherapy-Induced Peripheral Neuropathy and Treatment","authors":"Okan Ermiş, D. Akçalı","doi":"10.54875/jarss.2023.06977","DOIUrl":"https://doi.org/10.54875/jarss.2023.06977","url":null,"abstract":"ABSTRACT Chemotherapy induced peripheral neuropathy is a syndrome with distal symmetrical sensorial-dominant pain, tingling and numbness caused by neurotoxic chemotherapeutic agents. The severity increases with cumulative doses of chemotherapy, besides decrease in quality of life, may lead to cessation of treatment which may effect survival. Neurotoxicity causes large fiber and small fiber neuropathy through many pathologic mechanisms including mitochondrial dysfunction and oxidative stress. Dose related neuropathic pain is most commonly seen with taxanes, platins, vinca alkaloids, bortezomib and brentuximab. There is a limited effect of anticonvulsant and antidepressant medication for treatment. In this review awareness about chemotherapy induced peripheral neuropathy, prevention and treatment are discussed. Keywords: Chemotherapy, pain, neuropathy, small fiber neuropathy","PeriodicalId":36000,"journal":{"name":"Anestezi Dergisi","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43491763","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ultrasound-Guided Superficial Serratus Anterior Plane Block for Cardiac Surgery with Median Sternotomy: A Retrospective Study 超声引导下锯浅肌前平面阻滞用于胸骨正中切开术的心脏手术:回顾性研究
Q4 Medicine Pub Date : 2023-04-28 DOI: 10.54875/jarss.2023.19942
Aslıhan Aykut, N. Salman, Z. A. Demir
Objective: As part of multimodal analgesia regimen in cardiac surgery, the serratus anterior plane block (SAPB) is a technique regularly used in minimally invasive surgical interventions with thoracotomy. The aim of our study is to determine the analgesic efficacy of SAPB for cardiac surgery performed with sternotomy. Methods: A total of 99 patients who underwent SAPB (Group SAP, n=43) and conventional analgesia (Group C, n=56) for coronary artery bypass graft (CABG) surgery were compared retrospectively. Demographic data, postoperative opioid use, highest pain scores, nausea-vomiting, time to start oral intake, extubation time, lenght of intensive care unit and hospital stay were recorded. Results: Total opioid requirement, expressed in oral morphine equivalent within the first 24 hours after extubation, was found to be significantly lower in patients with SAPB (p=0.022). Similarly, both the highest reported pain scores at rest and during mobilization and also the nausea scores were found to be significantly lower in Group SAP during the same period (p=0.007, p=0.048, p=0.004). Extubation (p=0.025) and oral intake initiation time p=0.030) were shorter in Group SAP. Conclusion: By providing analgesia of the chest tube drain site, SAPB application was associated with lower opioid consumption, pain, and nausea-vomiting among patients who underwent CABG with median sternotomy. Because of this benefit, superficial SAPB may be part of opioid-reducing multimodal analgesia in cardiac surgery. Keywords: Serratus anterior plane block, fascial plane blocks, coronary artery bypass surgery, postoperative analgesia
目的:作为心脏外科多模式镇痛方案的一部分,锯齿状前平面阻滞(SAPB)是一种经常用于开胸微创手术干预的技术。我们研究的目的是确定SAPB对胸骨切开术后心脏手术的镇痛效果。方法:对99例接受SAPB(SAP组,n=43)和常规镇痛(C组,n=56)冠状动脉搭桥术的患者进行回顾性比较。记录人口统计学数据、术后阿片类药物的使用、最高疼痛评分、恶心呕吐、开始口服的时间、拔管时间、重症监护室的时间和住院时间。结果:在拔管后的前24小时内,以口服吗啡当量表示的阿片类药物总需求量在SAPB患者中显著降低(p=0.022),SAP组报告的休息和活动期间的最高疼痛评分以及恶心评分均显著低于同期(p=0.007,p=0.048,p=0.004)。SAP组的拔管时间(p=0.025)和口服开始时间(p=0.030)更短。结论:在胸骨正中切开术后接受冠状动脉旁路移植术的患者中,通过提供胸管引流部位的镇痛,SAPB的应用可降低阿片类药物的消耗、疼痛和恶心呕吐。由于这种益处,浅表SAPB可能是心脏手术中阿片类药物减少多模式镇痛的一部分。关键词:Serratus前平面阻滞、筋膜平面阻滞、冠状动脉搭桥术、术后镇痛
{"title":"Ultrasound-Guided Superficial Serratus Anterior Plane Block for Cardiac Surgery with Median Sternotomy: A Retrospective Study","authors":"Aslıhan Aykut, N. Salman, Z. A. Demir","doi":"10.54875/jarss.2023.19942","DOIUrl":"https://doi.org/10.54875/jarss.2023.19942","url":null,"abstract":"Objective: As part of multimodal analgesia regimen in cardiac surgery, the serratus anterior plane block (SAPB) is a technique regularly used in minimally invasive surgical interventions with thoracotomy. The aim of our study is to determine the analgesic efficacy of SAPB for cardiac surgery performed with sternotomy. Methods: A total of 99 patients who underwent SAPB (Group SAP, n=43) and conventional analgesia (Group C, n=56) for coronary artery bypass graft (CABG) surgery were compared retrospectively. Demographic data, postoperative opioid use, highest pain scores, nausea-vomiting, time to start oral intake, extubation time, lenght of intensive care unit and hospital stay were recorded. Results: Total opioid requirement, expressed in oral morphine equivalent within the first 24 hours after extubation, was found to be significantly lower in patients with SAPB (p=0.022). Similarly, both the highest reported pain scores at rest and during mobilization and also the nausea scores were found to be significantly lower in Group SAP during the same period (p=0.007, p=0.048, p=0.004). Extubation (p=0.025) and oral intake initiation time p=0.030) were shorter in Group SAP. Conclusion: By providing analgesia of the chest tube drain site, SAPB application was associated with lower opioid consumption, pain, and nausea-vomiting among patients who underwent CABG with median sternotomy. Because of this benefit, superficial SAPB may be part of opioid-reducing multimodal analgesia in cardiac surgery. Keywords: Serratus anterior plane block, fascial plane blocks, coronary artery bypass surgery, postoperative analgesia","PeriodicalId":36000,"journal":{"name":"Anestezi Dergisi","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46046827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Role of Ultrasonography in Confirming the Position of the Laryngeal Mask Airway in Adult Patients 超声检查在成人喉罩气道定位中的作用
Q4 Medicine Pub Date : 2023-04-28 DOI: 10.54875/jarss.2023.50103
F. Atar, G. Keskin, F. Akaslan, A. Donmez
Objective: The study aims to evaluate the Proseal laryngeal mask airway (PLMA) position with ultrasonographic imaging. Methods: The study included American Society of Anesthesiologists I-III patients with Mallampati scores I-II and operated using PLMA as an airway device. Before PLMA insertion, the glottic aperture was assessed by ultrasonography (USG). After PLMA placement, the USG evaluation was repeated. The symmetry of the arytenoid cartilages was examined. Asymmetry of an arytenoid to the glottic midline and the other arytenoid was graded 0 to 3 (USG arytenoid grade). After PLMA was placed, fiber optic bronchoscopy (FOB) was done to evaluate the PLMA position (FOB LMA grade). The relationship between USG arytenoid grade and FOB LMA grade was examined. Results: Forty-eight patients were included in the study. The mean age was 49 ± 15.8 (19-82), and 25 were female. It was determined that PLMA was in the correct position in 81.3% of the evaluation with USG and 68.8% of the assessment with FOB. USG arytenoid grade correlated with FOB LMA grade (r= -.582, p<.001). To detect a rotated LMA, USG had a sensitivity of 100% (%95 CI, 39.8 – 100.0) and a specificity of %80 (%95 CI, 22.8 – 99.8). The positive and negative predictive values were %97.7 (%95 CI, 88.0 – 99.9) and %100 (%95 CI, 91.8 – 100.0), respectively. The accuracy was %97.9 (%95 CI, 86.3 – 99.3). Conclusion: Ultrasonografi can be a simple, noninvasive, and reliable method to confirm PLMA placement in anesthesia practice. Keywords: Laryngeal mask airway, ultrasonography, airway management
目的:应用超声成像技术评价喉罩气道(PLMA)的位置。方法:该研究包括美国麻醉师协会I-III的Mallampati评分为I-II的患者,并使用PLMA作为气道装置进行手术。PLMA插入前,通过超声检查(USG)评估声门开口。放置PLMA后,重复USG评估。检查了杓状软骨的对称性。一个杓与声门中线不对称,另一个杓鹬分级为0至3(USG杓鹬级)。放置PLMA后,进行光纤支气管镜检查(FOB)以评估PLMA位置(FOB LMA等级)。研究了USG类杓级别和FOB LMA级别之间的关系。结果:48名患者被纳入研究。平均年龄49±15.8(19-82),女性25例。确定PLMA在USG评估的81.3%和FOB评估的68.8%中处于正确位置。USG杓状物分级与FOB LMA分级相关(r=-.582,p<.001)。检测旋转LMA,USG的敏感性为100%(%95 CI,39.8–100.0),特异性为%80(%95 CI,22.8–99.8)。阳性和阴性预测值分别为%97.7(%95 CI88.0–99.9)和%100(%95%CI,91.8–100.00)。准确率为%97.9(95%CI,86.3–99.3)。结论:在麻醉实践中,超声心动图是一种简单、无创、可靠的PLMA定位方法。关键词:喉罩气道,超声检查,气道管理
{"title":"The Role of Ultrasonography in Confirming the Position of the Laryngeal Mask Airway in Adult Patients","authors":"F. Atar, G. Keskin, F. Akaslan, A. Donmez","doi":"10.54875/jarss.2023.50103","DOIUrl":"https://doi.org/10.54875/jarss.2023.50103","url":null,"abstract":"Objective: The study aims to evaluate the Proseal laryngeal mask airway (PLMA) position with ultrasonographic imaging. Methods: The study included American Society of Anesthesiologists I-III patients with Mallampati scores I-II and operated using PLMA as an airway device. Before PLMA insertion, the glottic aperture was assessed by ultrasonography (USG). After PLMA placement, the USG evaluation was repeated. The symmetry of the arytenoid cartilages was examined. Asymmetry of an arytenoid to the glottic midline and the other arytenoid was graded 0 to 3 (USG arytenoid grade). After PLMA was placed, fiber optic bronchoscopy (FOB) was done to evaluate the PLMA position (FOB LMA grade). The relationship between USG arytenoid grade and FOB LMA grade was examined. Results: Forty-eight patients were included in the study. The mean age was 49 ± 15.8 (19-82), and 25 were female. It was determined that PLMA was in the correct position in 81.3% of the evaluation with USG and 68.8% of the assessment with FOB. USG arytenoid grade correlated with FOB LMA grade (r= -.582, p<.001). To detect a rotated LMA, USG had a sensitivity of 100% (%95 CI, 39.8 – 100.0) and a specificity of %80 (%95 CI, 22.8 – 99.8). The positive and negative predictive values were %97.7 (%95 CI, 88.0 – 99.9) and %100 (%95 CI, 91.8 – 100.0), respectively. The accuracy was %97.9 (%95 CI, 86.3 – 99.3). Conclusion: Ultrasonografi can be a simple, noninvasive, and reliable method to confirm PLMA placement in anesthesia practice. Keywords: Laryngeal mask airway, ultrasonography, airway management","PeriodicalId":36000,"journal":{"name":"Anestezi Dergisi","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46100015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Second Victim Phenomenon Experience of the Anesthesia Team: A Focus Group Study 麻醉小组的第二次受害者现象经验:焦点小组研究
Q4 Medicine Pub Date : 2023-04-28 DOI: 10.54875/jarss.2023.60024
P. Ayvat
Objective: As a result of the negative events experienced, the patient becomes the first victim, while the healthcare provider becomes the second victim. This situation is frequently experienced in the operating room (OR) and intensive care unit (ICU). Our aim is to reveal the problems and experiences of the anesthesia personnel working in OR / ICU regarding the second victim phenomenon (SVP) and to propose solutions. Methods: The research was conducted with the qualitative research method. Focus group interviews were conducted with six volunteer healthcare personnel working in OR / ICU. The data was written down and thematic content analysis was done through MAXQDA 22. Results: 5 main themes and 21 subthemes were reached. These main themes can be counted as the frequency of experiencing SVP, the main problems, emotions/feelings, coping methods, and suggestions/requests. The anesthesia team encountered the SVP frequently and this could be due to medical, violent, or technical reasons. In this situation, they felt worthlessness, helplessness, injustice, anger, and aggression. In order to cope with the SVP, they use methods such as self-suggestion, taking a break, calming down, and sharing with colleagues. As suggestions, they demanded psychological, legal, technical, managerial, physiotherapy, peer, and academic support as well as free time, elimination of patient complaints, and increased hospital security. Conclusion: The operating room and intensive care units are the busiest departments, and the frequency of adverse events is very high. Some of the situations that cause to feel SVP are preventable problems. Being aware of what you feel and how to overcome it will increase the quality of health service delivery and reduce the burnout status of health workers. Keywords: Patient safety, anesthesia, critical care
目的:由于所经历的负面事件,患者成为第一受害者,而医疗保健提供者成为第二受害者。这种情况经常发生在手术室(OR)和重症监护病房(ICU)。我们的目的是揭示麻醉人员在手术室/ ICU工作中遇到的关于第二受害者现象(SVP)的问题和经验,并提出解决方案。方法:采用定性研究方法。对6名在OR / ICU工作的志愿医护人员进行焦点小组访谈。记录数据并通过MAXQDA 22进行专题内容分析。结果:达到5个主题,21个副主题。这些主题可以计算为经历SVP的频率、主要问题、情绪/感受、应对方法和建议/请求。麻醉小组经常遇到高级副总裁,这可能是由于医疗、暴力或技术原因。在这种情况下,他们感到毫无价值、无助、不公正、愤怒和攻击性。为了应对高级副总裁,他们使用了自我暗示、休息、冷静下来、与同事分享等方法。作为建议,他们要求心理、法律、技术、管理、物理治疗、同伴和学术支持,以及空闲时间,消除患者投诉,加强医院安全。结论:手术室和重症监护病房是最繁忙的科室,不良事件发生的频率很高。一些导致感觉SVP的情况是可以预防的问题。了解自己的感受以及如何克服这些感受将提高卫生服务的质量,并减少卫生工作者的倦怠状态。关键词:患者安全,麻醉,重症监护
{"title":"The Second Victim Phenomenon Experience of the Anesthesia Team: A Focus Group Study","authors":"P. Ayvat","doi":"10.54875/jarss.2023.60024","DOIUrl":"https://doi.org/10.54875/jarss.2023.60024","url":null,"abstract":"Objective: As a result of the negative events experienced, the patient becomes the first victim, while the healthcare provider becomes the second victim. This situation is frequently experienced in the operating room (OR) and intensive care unit (ICU). Our aim is to reveal the problems and experiences of the anesthesia personnel working in OR / ICU regarding the second victim phenomenon (SVP) and to propose solutions. Methods: The research was conducted with the qualitative research method. Focus group interviews were conducted with six volunteer healthcare personnel working in OR / ICU. The data was written down and thematic content analysis was done through MAXQDA 22. Results: 5 main themes and 21 subthemes were reached. These main themes can be counted as the frequency of experiencing SVP, the main problems, emotions/feelings, coping methods, and suggestions/requests. The anesthesia team encountered the SVP frequently and this could be due to medical, violent, or technical reasons. In this situation, they felt worthlessness, helplessness, injustice, anger, and aggression. In order to cope with the SVP, they use methods such as self-suggestion, taking a break, calming down, and sharing with colleagues. As suggestions, they demanded psychological, legal, technical, managerial, physiotherapy, peer, and academic support as well as free time, elimination of patient complaints, and increased hospital security. Conclusion: The operating room and intensive care units are the busiest departments, and the frequency of adverse events is very high. Some of the situations that cause to feel SVP are preventable problems. Being aware of what you feel and how to overcome it will increase the quality of health service delivery and reduce the burnout status of health workers. Keywords: Patient safety, anesthesia, critical care","PeriodicalId":36000,"journal":{"name":"Anestezi Dergisi","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43711679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Anestezi Dergisi
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1