Clinical Nutrition Open Science最新文献

{"title":"Prevalence of sarcopenia, sarcopenia obesity and their association with nutritional status among elderly residents in a Hanoi aged care center, Vietnam","authors":"Thuy Linh Nguyen ,&nbsp;Tuan Minh Tran ,&nbsp;Thi Quynh Trang Tran ,&nbsp;Thanh Nga Ta ,&nbsp;Thi Phuong Duong","doi":"10.1016/j.nutos.2025.12.010","DOIUrl":"10.1016/j.nutos.2025.12.010","url":null,"abstract":"<div><h3>Background</h3><div>Sarcopenia and sarcopenic obesity (SO) are increasingly recognized as important geriatric syndromes, often associated with poor nutritional status and altered body composition. However, data on these conditions among institutionalized elderly in Vietnam remain limited. This study aimed to determine the prevalence of sarcopenia and SO and to examine their associations with nutritional status in an aged care center in Hanoi, Vietnam.</div></div><div><h3>Methods</h3><div>A cross-sectional study was conducted among 93 residents aged ≥60 years. Sarcopenia and SO were diagnosed based on the criteria of the Asian Working Group for Sarcopenia (AWGS) and the ESPEN/EASO consensus. Nutritional status was assessed using body mass index (BMI) and the Mini Nutritional Assessment long-form (MNA-LF). Logistic regression was used to evaluate associations.</div></div><div><h3>Results</h3><div>The prevalence of sarcopenia and SO was 60.2% and 15.1%, respectively. Individuals with sarcopenia had significantly lower BMI, waist circumference, mid-upper arm circumference, fat mass, fat-free mass, total body water, phase angle, and body protein content (<em>P</em> &lt; 0.01). In contrast, those with SO had significantly higher BMI, waist circumference, fat mass, and visceral fat area, but lower skeletal muscle mass. Overweight status was inversely associated with sarcopenia (aOR = 0.03; 95% CI: 0.002–0.33; <em>P</em> = 0.004), while it significantly increased the odds of SO (aOR = 17.59; 95% CI: 2.05–150.81; <em>P</em> = 0.009).</div></div><div><h3>Conclusion</h3><div>Sarcopenia and sarcopenic obesity are highly prevalent among elderly residents in aged care facilities and are closely linked to nutritional status. Routine screening of nutritional status and body composition should be prioritized to support early detection and personalized interventions in this vulnerable population.</div></div>","PeriodicalId":36134,"journal":{"name":"Clinical Nutrition Open Science","volume":"65 ","pages":"Article 100616"},"PeriodicalIF":0.0,"publicationDate":"2025-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145979064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The association between diet quality and risk of malnutrition in Mexican Community-dwelling older adults: Evidence from a cross-sectional study","authors":"Helen Joceline Vidaña-Espinoza ,&nbsp;Susan B. Roberts ,&nbsp;Omar Yaxmehen Bello-Chavolla ,&nbsp;Mónica Ancira-Moreno ,&nbsp;Ana Paola Jiménez-Reyna ,&nbsp;Miriam Teresa López-Teros","doi":"10.1016/j.nutos.2025.12.009","DOIUrl":"10.1016/j.nutos.2025.12.009","url":null,"abstract":"<div><h3>Background and Aim</h3><div>Older adults are at increased risk of consuming unhealthy diets, which may lead to poor nutritional status. This study examined the association between overall diet quality and risk of malnutrition in community-dwelling older adults living in Mexico City.</div></div><div><h3>Methods</h3><div>This secondary analysis used baseline data from the prospective cohort “Frailty, Dynapenia, and Sarcopenia in Mexican Adults (FraDySMex),” conducted in three municipalities in southeast Mexico City: Cuajimalpa, Magdalena Contreras, and Álvaro Obregón. A Comprehensive Geriatric Assessment was performed, including evaluation of nutritional status, dietary intake, and health indicators. Nutritional status was assessed using the Mini Nutritional Assessment–Short Form. Dietary intake was evaluated with a validated semi-quantitative food frequency questionnaire, and overall diet quality was determined using the Healthy Eating Index 2020. Covariates included sociodemographic characteristics, dependency level, comorbidities, age, and sex. Multiple logistic regression models were used to assess associations between diet quality and malnutrition risk, considering body fat percentage as an effect modifier.</div></div><div><h3>Results</h3><div>A total of 366 participants (mean age 72.6 ± 7.6 years; 78.1% women) were included. Among them, 34.0% were at risk of malnutrition. The mean caloric intake was 2044 ± 555 kcal, and 20.0 % of participants had poor diet quality (≤20th percentile). The regression analyses indicated that fat mass modified the relationship between diet quality and malnutrition risk. A significant association was found among individuals with normal fat mass (odds ratio 4.28; 95 % confidence interval 1.60–11.45) after adjusting for dependency, comorbidity, age, and sex, whereas no significant association was observed among participants with excess fat mass.</div></div><div><h3>Conclusion</h3><div>Low diet quality was associated with malnutrition risk only in older adults without excess body fat. These findings highlight the importance of promoting healthy diets to prevent malnutrition in this rapidly growing population.</div></div>","PeriodicalId":36134,"journal":{"name":"Clinical Nutrition Open Science","volume":"65 ","pages":"Article 100615"},"PeriodicalIF":0.0,"publicationDate":"2025-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145939687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Navigating obesity through nutrigenetic dietary interventions: Evidence from young Saudi women","authors":"Saba Aljasir ,&nbsp;Noura Eid ,&nbsp;Emanuela V. Volpi ,&nbsp;Nora Mohammad Bin Obaid ,&nbsp;Ihab Tewfik","doi":"10.1016/j.nutos.2025.12.008","DOIUrl":"10.1016/j.nutos.2025.12.008","url":null,"abstract":"<div><h3>Background</h3><div>Nutrigenetic dietary interventions offer personalised strategies for weight management, yet evidence from Middle Eastern populations—particularly young Saudi women—remains limited. This study examined the effect of a three-month nutrigenetic intervention on body weight and adiponectin levels.</div></div><div><h3>Methods</h3><div>Thirty-one Saudi women aged 18–24 years with overweight or obesity completed a personalised nutrigenetic intervention informed by variants in six genes (<em>FTO, MC4R, CLOCK, PPARG, LPL, TCF7L2</em>). Anthropometric and biochemical markers were measured at baseline and post-intervention. Weight and adiponectin changes were analysed using Wilcoxon signed-rank tests; genotype-group differences were assessed using Kruskal–Wallis tests.</div></div><div><h3>Results</h3><div>Weight significantly decreased (median change: −1.3 kg; p = 0.008). Adiponectin concentrations increased significantly (median change: +1.74 μg/mL; p &lt; 0.001). No significant genotype-specific differences were observed for weight or adiponectin outcomes (all p &gt; 0.05).</div></div><div><h3>Conclusions</h3><div>This nutrigenetic dietary intervention produced clinically meaningful improvements in weight and metabolic biomarkers independent of genotype. Findings support the feasibility of integrating personalised nutrition into obesity-management strategies for young Saudi women.</div></div>","PeriodicalId":36134,"journal":{"name":"Clinical Nutrition Open Science","volume":"65 ","pages":"Article 100614"},"PeriodicalIF":0.0,"publicationDate":"2025-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145979061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relative validity of surrogate measures within the global leadership initiative on malnutrition (GLIM) phenotypic criteria for diagnosing adult malnutrition in resource-constrained settings","authors":"E. Van Tonder ,&nbsp;F.A.M. Wenhold ,&nbsp;T. Esterhuizen ,&nbsp;R. Blaauw","doi":"10.1016/j.nutos.2025.12.012","DOIUrl":"10.1016/j.nutos.2025.12.012","url":null,"abstract":"<div><h3>Background and aim</h3><div>Implementing the Global Leadership Initiative on Malnutrition (GLIM) diagnostic criteria may improve adult malnutrition identification. Some GLIM parameters are challenging to obtain in resource-constrained settings. We assessed the relative validity of accessible surrogates in substituting accepted phenotypic diagnostic criteria within GLIM.</div></div><div><h3>Methods</h3><div>In a prospective diagnostic accuracy study, adult ambulatory patients with diverging diagnoses from five South African hospitals were consecutively sampled. The Malnutrition Universal Screening Tool (MUST score≥1) and GLIM diagnostic criteria determined malnutrition risk and diagnosis respectively. Surrogates investigated for appendicular skeletal muscle mass index (ASMMI), measured by multifrequency bio-electrical impedance, were mid-upper arm circumference (MUAC) and body mass index-adjusted calf circumference (CC). Pearson correlation coefficients, receiver operating characteristics curve analysis, Youden's index, sensitivity (Se), specificity (Sp), and Cohen's kappa were used.</div></div><div><h3>Results</h3><div>Among 480 patients screened (51% male; mean age: 47.03 years, SD 14.87), 73% (<em>n</em> = 350) were at malnutrition risk. Of these, 54% (<em>n</em> = 189) were malnourished (GLIM criteria). MUAC and CC moderately correlated with ASMMI (<em>r</em> = 0.645; <em>P</em>&lt;0.001 and <em>r</em> = 0.515; <em>P</em>&lt;0.001 respectively). Optimal cut-offs for surrogates, with corresponding diagnostic accuracy, were: MUAC for ASMMI: 24.9 cm (area under the curve (AUC) = 0.857, Se = 85%, Sp = 74%) and CC for ASMMI: 29.1 cm (AUC = 0.819, Se = 73%, Sp = 83%). Substituting MUAC and CC for ASMMI at study-specific cut-offs - within the GLIM phenotypic criteria - was relatively valid (MUAC: kappa = 0.925, Se = 100%, Sp = 91%; CC: kappa = 0.849, Se = 100%, Sp = 91%).</div></div><div><h3>Conclusion</h3><div>Within GLIM and using the reported cut-offs, MUAC reflects ASMMI. BMI-adjusted CC can replace low skeletal muscle mass. Valid, easy-to-use surrogates may enhance the feasibility of the GLIM diagnostic framework, particularly where resources are constrained.</div></div>","PeriodicalId":36134,"journal":{"name":"Clinical Nutrition Open Science","volume":"65 ","pages":"Article 100618"},"PeriodicalIF":0.0,"publicationDate":"2025-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145885958","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Role of excessive fructose consumption on liver health","authors":"Lidianys María Lewis Lujan ,&nbsp;Natalia Madrid Molina ,&nbsp;Diego Emmanuel Guerrero-Magaña ,&nbsp;Annette Pulcherie Iloki Lewis ,&nbsp;Marisol Reséndiz Zarazúa ,&nbsp;Andres Enrique Rivera Vizcarra ,&nbsp;María del Carmen Carranza Peña ,&nbsp;Karla Isabel Moreno López ,&nbsp;Cesar Benjamin Otero Leon ,&nbsp;Simon Bernard Iloki-Assanga","doi":"10.1016/j.nutos.2025.12.007","DOIUrl":"10.1016/j.nutos.2025.12.007","url":null,"abstract":"<div><div>Non-alcoholic fatty liver disease (NAFLD) refers to a group of conditions characterized by excessive accumulation of fat in the liver in people with low or no alcohol consumption. The simplest or most common form of this condition is fatty liver, a non-serious condition in which fat is deposited in liver cells, where fructose and glucose play an influential role in this condition, and excessive fructose consumption can lead to lipid accumulation in the liver, which is associated with the development of non-alcoholic fatty liver disease. It has been significantly related to the intake of added fructose in the diet, being considered a relevant risk factor for its development, obesity, as well as other liver-related diseases. With the increasing availability of high-calorie foods, the use of fructose as a sweetener has been implicated in the increasing prevalence of NAFLD and metabolic syndrome. NAFLD may be benign in many cases, an increasing percentage of patients may progress to non-alcoholic steatohepatitis (NASH), which is characterized by inflammation and liver damage. In the context of NAFLD, poor glucose management may contribute to fat accumulation in the liver, one of the key factors in the development of this disease.</div></div>","PeriodicalId":36134,"journal":{"name":"Clinical Nutrition Open Science","volume":"65 ","pages":"Article 100613"},"PeriodicalIF":0.0,"publicationDate":"2025-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145885959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The relationship between prebiotic and probiotic foods consumption and the nutritional status of high school students aged 15–18: A cross- sectional study","authors":"Sayu Putu Yuni Paryati ,&nbsp;Carissa Wityadarda ,&nbsp;Nadia Amanda ,&nbsp;Mayfa Yemima S ,&nbsp;Adi Anggoro Parulian ,&nbsp;Bernadette Victoria ,&nbsp;Moch Novian Saputra ,&nbsp;Teresa Ester Sekar Kinasih ,&nbsp;Fernando Diaz Ndopo ,&nbsp;Augustinus Lahagu ,&nbsp;Lira Apriani Simbolon ,&nbsp;Nasya Salsabila Aditiyan ,&nbsp;F.X. Widiantoro","doi":"10.1016/j.nutos.2025.12.004","DOIUrl":"10.1016/j.nutos.2025.12.004","url":null,"abstract":"<div><h3>Introduction</h3><div>Adolescence experience rapid growth and requires optimal nutrition. Prebiotics and probiotics foods contribute to gut microbiota balance, influencing digestion and nutrient absorption which manifest on the nutritional status. However, the data intake of these foods among Indonesian adolescents remains limited. This study aimed to examines the association between consumption of prebiotic and probiotic food sources and nutritional status among high school students in West java, Indonesia.</div></div><div><h3>Methods</h3><div>Design: A Cross-sectional analytic observational study.</div></div><div><h3>Setting</h3><div>SMA Negeri 2 Padalarang, West Bandung Regency, West Java, Indonesia.</div></div><div><h3>Participants</h3><div>306 students (grades X-XII) selected through stratified random sampling. All completed the study. Measurements: A food frequency questionnaire assessed intake of prebiotic and probiotic sources. Nutritional status was determined using Body mass Index (BMI) for age.</div></div><div><h3>Results</h3><div>Fermented food (<em>r</em> = −0.139, <em>p</em> = 0.015) and vegetable consumption (<em>r</em> = −0.477, <em>p</em> &lt; 0.001) were negatively associated with BMI, indicating higher intake corresponding with lower BMI. In Contrast, Cerealia (<em>r</em> = 0.165, <em>p</em> = 0.004) and chocolate products consumption (<em>r</em> = 0.388, <em>p</em> &lt; 0.001) were positively associated with BMI. Meanwhile, fruit, nut, and legumes intake showed no significant relationship. Both prebiotic and probiotic intake accounted for 35.5% of the variation in nutritional status (<em>R</em>² = 0.355).</div></div><div><h3>Conclusions</h3><div>Consumption of fermented foods and vegetables is associated with lower BMI, while cereals and chocolate products are linked to higher BMI among adolescents. Dietary patterns involving prebiotic and probiotic sources may influence adolescent nutritional status. However, other contributing factors should be considered in future interventions.</div></div>","PeriodicalId":36134,"journal":{"name":"Clinical Nutrition Open Science","volume":"65 ","pages":"Article 100610"},"PeriodicalIF":0.0,"publicationDate":"2025-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145885962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Does skeletal muscle weakness recognized early during hospitalization for acute heart failure predict short-term mortality?","authors":"Vinicius Ferigato,&nbsp;Fernanda Takeyama,&nbsp;Felipe Rocha,&nbsp;Giulio Checchinato,&nbsp;Bruna Eduarda Gandra,&nbsp;Bruno Maciel,&nbsp;Marina May Antonio,&nbsp;Beatriz Santana Silva,&nbsp;Helder Jorge A. Gomes,&nbsp;Alcides Rocha","doi":"10.1016/j.nutos.2025.12.006","DOIUrl":"10.1016/j.nutos.2025.12.006","url":null,"abstract":"<div><h3>Introduction</h3><div>Impairment of skeletal muscle is common in heart failure (HF) but understudied in acute episodes.</div></div><div><h3>Objective</h3><div>To assess the relationship between skeletal muscle weakness identified early during hospitalization for acute HF and the risk of hospital mortality.</div></div><div><h3>Methodology</h3><div>we conducted a prospective, single center study enrolling patients ≥ 18 years old admitted from the emergency department with acute HF (March 2023–April 2024). We excluded individuals with other causes of muscle weakness, including dementia, delirium and cerebrovascular disease. In the ward, a physical educator performed handgrip tests and values &lt; 27 (men) and 16 kg (women) were used to define muscle weakness (according to EWGSOP2). In the same day, all participants underwent clinical examination by a cardiologist who assessed signs of congestion and hypoperfusion to classify patients into the 4 clinical-hemodynamic profiles established in the literature (A, B, C and L).</div></div><div><h3>Results</h3><div>The sample consisted of 37 participants, who were 68 (±15) years old (mean ± standard deviation) and predominantly men (68%). We performed the study procedures in 2 (2) days (median and interquartile range) after patients arrived at the emergency department. The handgrip tests identified 15 participants with skeletal muscle weakness (40% of the sample). This group had more severe clinical presentations of HF, with a higher proportion of participants showing both congestion and hypoperfusion signs (profile C) than the group with normal strength (47 vs 5%; <em>P</em> = 0.020). The in-hospital mortality rate was 33% in the group with muscle weakness compared to 5% in the group with normal strength (<em>P</em> = 0.031). A logistic regression model (Chi-square = 5.568; df =1; <em>P</em> = 0,018; R² = 0.238) showed muscle weakness as the only variable independently associated with hospital mortality (<em>P</em> = 0.043).</div></div><div><h3>Conclusion</h3><div>Early recognition of muscle weakness identified a group of patients with acute HF at increased risk of hospital mortality.</div></div>","PeriodicalId":36134,"journal":{"name":"Clinical Nutrition Open Science","volume":"65 ","pages":"Article 100612"},"PeriodicalIF":0.0,"publicationDate":"2025-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145814422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Geriatric nutritional risk index predicted survival time in multiple myeloma","authors":"Kazuhito Suzuki ,&nbsp;Tadahiro Gunji ,&nbsp;Riku Nagao ,&nbsp;Masaharu Kawashima ,&nbsp;Hideki Uryu ,&nbsp;Mamiko Momoki ,&nbsp;Hiroto Ishii ,&nbsp;Ryoko Fukushima ,&nbsp;Mitsuji Katori ,&nbsp;Hiroki Yokoyama ,&nbsp;Atsushi Katsube ,&nbsp;Takeshi Saito ,&nbsp;Kaichi Nishiwaki ,&nbsp;Shingo Yano","doi":"10.1016/j.nutos.2025.12.003","DOIUrl":"10.1016/j.nutos.2025.12.003","url":null,"abstract":"<div><h3>Introduction</h3><div>Geriatric nutritional risk index (GNRI), an indicator of nutritional status, has been shown to predict overall survival (OS) in patients with hematological malignancies. However, GNRI has never been investigated in myeloma patients. This retrospective study aimed to investigate the clinical significance of GNRI in myeloma patients.</div></div><div><h3>Materials and Methods</h3><div>We reviewed the medical records of patients with newly diagnosed multiple myeloma, who had received proteasome inhibitor and/or immunomodulatory drug as initial chemotherapy from 2009 to 2022, with follow-up until December 2023. GNRI is calculated as [(14.89 × serum albumin level) + (41.7 × current body weight/ideal body weight)]. Based on previous reports, the GNRI cut-off for high-risk patients is 92.</div></div><div><h3>Results</h3><div>Three hundred and fifty-seven patients were included in this study. The median age was 71 years. The median and mean values of GNRI were 93.2 and 92.4 (±13.8), respectively. Using receiver operator characteristics (ROC) curves, a cutoff of 91.4 yielded the highest area under the curve (AUC). The proportion of patients classified as high GNRI risk was 46.8 %. In a median followed-up time of 37.8 months, OS in the high GNRI risk group was significantly shorter than that in the low GNRI risk group (3 year-OS: 66.7 % and 83.1 %; <em>P</em> &gt; 0.001). In multivariate analysis, high GNRI risk was independently associated with poorer OS (HR 1.716, <em>P</em> = 0.016), whereas PS and simplified frailty score were not. The GNRI risk was improved during treatment overtime; the frequencies of GNRI risk at 3, 6, and 12 months after treatment was initiated was 40.0 %, 32.3 %, and 29.9 %, respectively. The GNRI risk assessed at 12 months predicted subsequent OS more accurately than the baseline GNRI, as demonstrated by ROC analysis (AUC, 0.690 <em>vs</em>. 0.582; <em>P</em> = 0.009). Patients whose GNRI improved from high risk at diagnosis to low risk at 12 months had OS comparable with those with low risk at diagnosis, suggesting that improved GNRI risk predicted good prognosis.</div></div><div><h3>Conclusion</h3><div>High GNRI risk at diagnosis predicted short OS in myeloma patients. The GNRI risk changed overtime during treatment, and a dynamic GNRI model predicted OS in myeloma patients.</div></div>","PeriodicalId":36134,"journal":{"name":"Clinical Nutrition Open Science","volume":"65 ","pages":"Article 100609"},"PeriodicalIF":0.0,"publicationDate":"2025-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145814421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of nutritional and lifestyle counselling on anthropometrics of pre-diabetic subjects","authors":"Deepashri C.V. ,&nbsp;M.S. Hemalatha ,&nbsp;Chhavi Mehra ,&nbsp;Shivtosh Kumar ,&nbsp;Annie Mattilda Raymond","doi":"10.1016/j.nutos.2025.12.001","DOIUrl":"10.1016/j.nutos.2025.12.001","url":null,"abstract":"<div><div>Prediabetes is an important intermediate stage in the transition to type 2 diabetes mellitus and relates to increased cardio metabolic burden. Nutritional counselling represents a potential intervention to alleviate low metabolic health; however, its effect on anthropometric indices in pre-diabetics needs to be further elucidated. The aim of this study was to assess the effect of nutritional counselling on key anthropometric markers, including weight, body mass index (BMI), waist circumference (WC) and waist-to-height ratio (WHtR) in a cohort of prediabetes patients. 499 subjects were remotely recruited between the age of 20 and 60 years via a partnering healthcare organization who met the inclusion and exclusion criteria. Participants were instructed through standardized videos (pre-recorded) and protocols on how to correctly assess their weight, height and waist circumference (working with digital scales and non-elastic measuring tapes). Data were obtained through an online diabetic reversal platform, which included a 24-hour food recall personalized nutrition counselling and physical activity. All anthropometric indices were calculated and classified according to the Asian specific cut points. Participants who completed the nutritional counselling intervention demonstrated significant improvements from baseline in all anthropometric measures, including weight, BMI, and waist circumference. These improvements were also significantly greater than those observed in a non-intervention control group of non-completers. Males had the maximum decrease in weight in the age group of 20–30 years (mean loss −2.63 kg), while females had the maximum weight loss in 50–60-year group (mean loss −2.97 kg). Similar reductions in BMI, WC and Waist Height Ratio were noted, though many subjects remained above recommended thresholds for increased cardio metabolic risk. Nutritional counselling appears to provide relevant benefits for WC, WHtR, as well as enhancing weight &amp; amp; BMI improvements among pre-diabetics. Notably, however, despite these improvements, a considerable proportion of subjects still have high-risk levels, indicating the importance of continuing and prolonged lifestyle modification to lower the risk of progression to type 2 diabetes.</div></div>","PeriodicalId":36134,"journal":{"name":"Clinical Nutrition Open Science","volume":"65 ","pages":"Article 100607"},"PeriodicalIF":0.0,"publicationDate":"2025-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145842291","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Double burden of malnutrition in women of reproductive age in Morocco: A household-based survey","authors":"Fall Abdourahmane ,&nbsp;Lazrak Meryem ,&nbsp;El Ammari Laila ,&nbsp;Benjeddou Kaoutar ,&nbsp;Gamih Hasnae ,&nbsp;Yahyane Abdelhakim ,&nbsp;Baha Rabi ,&nbsp;Benjouad Abdelaziz ,&nbsp;Heikel Jaafar ,&nbsp;Barkat Amina ,&nbsp;Aguenaou Hassan ,&nbsp;El Kari Khalid ,&nbsp;El Hsaini Houda","doi":"10.1016/j.nutos.2025.12.002","DOIUrl":"10.1016/j.nutos.2025.12.002","url":null,"abstract":"<div><h3>Introduction</h3><div>The double burden of malnutrition (DBM) is a major challenge for developing countries. In Morocco, overall understanding of this phenomenon remains limited. National data indicate that women of reproductive age (WRA) are particularly affected: 61.3 % are overweight/obese, 34.4 % are anemic, 30.3 % suffer from iron deficiency (ID) and 49.7 % iron deficiency anemia (IDA).</div></div><div><h3>Objective</h3><div>The current study was conducted to determine the prevalence of DBM in Morocco, defined as coexistence of iron deficiency and overweight/obesity among women of reproductive age.</div></div><div><h3>Methods</h3><div>We conducted a nationally representative cross-sectional survey with a total of 2090 WRA focusing on both iron status and overweight/obesity. Data collection included blood sampling, socio-economic and anthropometric parameters. Biological analyses measured hemoglobin, ferritin and C-reactive protein (CRP).</div></div><div><h3>Results</h3><div>The results obtained revealed that 60.2 % of WRA were overweight/obese, with 30.7% having ID, 34.5% having anaemia and 50.0% having IDA. Overweight/obesity was associated with anemia in 19.4% of 2086 WRA (p &lt; 0.05), 30.7% classified as mild, 23.7% as moderate and 2.0% as severe (p &gt; 0.05). In addition, 17% of participants were diagnosed with iron deficiency, whereas iron deficiency anaemia was detected in 29.9% of participants. <u>(</u>With ID in 17.0% of 1987 WRA) (p &lt; 0.05) and with IDA in 29.9% of 1983 WRA (p &lt; 0.05). on the other hand, 32.3% of the 1254 overweight/obese WRA had anaemia, which was classified as mild in 54.5%, moderate in 42.0%, and severe in 3.5%. Iron deficiency was detected in 28.4% of 1189 WRA and iron deficiency anaemia in 54.3% of 1185 (p &gt; 0.05).</div></div><div><h3>Conclusion</h3><div>DBM among WRA highlights emerging reality of interconnected and simultaneous coexistence of undernutrition and overnutrition at individual level. This phenomenon, observed on a global scale and affecting millions of individuals, has significant implications for households and population.</div></div>","PeriodicalId":36134,"journal":{"name":"Clinical Nutrition Open Science","volume":"65 ","pages":"Article 100608"},"PeriodicalIF":0.0,"publicationDate":"2025-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145814423","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}