We propose the use of independent component analysis to find similarities of genomes. Considering different numbers of independent components, the complete linkage method was used to identify groups based on the estimated coefficients of the mixing matrix. The sequences analyzed correspond to the strains of the Mycobacterium tuberculosis genome, ten sequences were analyzed, obtained from the National Center for Biotechnology Information (NCBI, 2017). The GC-content of each sequence was evaluated using a sliding window of 10,000 bases. The clustering analysis using the independent components of the analyzed sequences was essential to verify the dissimilarity of the sequences.
{"title":"EVALUATION OF GENOME SIMILARITIES USING INDEPENDENT COMPONENTS","authors":"T. Sáfadi, L. M. Ferreira","doi":"10.28951/rbb.v38i1.439","DOIUrl":"https://doi.org/10.28951/rbb.v38i1.439","url":null,"abstract":"We propose the use of independent component analysis to find similarities of genomes. Considering different numbers of independent components, the complete linkage method was used to identify groups based on the estimated coefficients of the mixing matrix. The sequences analyzed correspond to the strains of the Mycobacterium tuberculosis genome, ten sequences were analyzed, obtained from the National Center for Biotechnology Information (NCBI, 2017). The GC-content of each sequence was evaluated using a sliding window of 10,000 bases. The clustering analysis using the independent components of the analyzed sequences was essential to verify the dissimilarity of the sequences.","PeriodicalId":36293,"journal":{"name":"Revista Brasileira de Biometria","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89771536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Marcílio Ramos Pereira Cardial, Juliana B. Fachini-Gomes, E. Nakano
This paper further develops the statistical inference procedure of the exponentiated discrete Weibull distribution (EDW) for data with the presence of censoring. This generalization of the discrete Weibull distribution has the advantage of being suitable to model non-monotone failure rates, such as those with bathtub and unimodal distributions. Inferences about EDW distribution are presented using both frequentist and bayesian approaches. In addition, the classical Likelihood Ratio Test and a Full Bayesian Significance Test (FBST) were performed to test the parameters of EDW distribution. The method presented is applied to simulated data and illustrated with a real dataset regarding patients diagnosed with head and neck cancer.
{"title":"EXPONENTIATED DISCRETE WEIBULL DISTRIBUTION FOR CENSORED DATA","authors":"Marcílio Ramos Pereira Cardial, Juliana B. Fachini-Gomes, E. Nakano","doi":"10.28951/rbb.v38i1.425","DOIUrl":"https://doi.org/10.28951/rbb.v38i1.425","url":null,"abstract":"This paper further develops the statistical inference procedure of the exponentiated discrete Weibull distribution (EDW) for data with the presence of censoring. This generalization of the discrete Weibull distribution has the advantage of being suitable to model non-monotone failure rates, such as those with bathtub and unimodal distributions. Inferences about EDW distribution are presented using both frequentist and bayesian approaches. In addition, the classical Likelihood Ratio Test and a Full Bayesian Significance Test (FBST) were performed to test the parameters of EDW distribution. The method presented is applied to simulated data and illustrated with a real dataset regarding patients diagnosed with head and neck cancer.","PeriodicalId":36293,"journal":{"name":"Revista Brasileira de Biometria","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83107841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. C. Filho, D. V. Cruz, E. C. A. Oliveira, V. Piscoya, G. R. Moreira, Ana Luíza Xavier Cunha, Renisson Neponuceno de Araújo Filho
§ ABSTRACT: In population genetics, it is very common to use statistical analysis to test the Hardy-Weinberg genetic equilibrium in a given population. The classical method of approaching this problem is done through the chi-square test that often leads to the verification of the equilibrium hypothesis. In the present work, a Bayesian analysis was developed involving hypothesis testing, estimation and credibility intervals to test this balance. Data on M, MN and N blood groups from the MNS system were used on samples from two populations, one from Brazilians and one from North Americans, obtained by Beiguelman (1977). The HardyWeinberg equilibrium adhesion chi-square test was performed, where the acceptance of the Hardy-Weinberg equilibrium hypothesis was confirmed. By Bayesian analysis, the rejection of the Hardy-Weinberg equilibrium hypothesis was confirmed, mainly by the Bayes factor. Our primary concern was to develop a Bayesian technique as an alternative to testing HardyWeinberg equilibrium using the MNSs blood sample data. The result obtained may encourage researchers mainly in the field of biological sciences to practice Bayesian Methodology, as an alternative in statistical tests.
{"title":"STATISTICAL ANALYSIS WITH A BAYESIAN APPROACH TO THE HARDY-WEINBERG EQUILIBRIUM","authors":"M. C. Filho, D. V. Cruz, E. C. A. Oliveira, V. Piscoya, G. R. Moreira, Ana Luíza Xavier Cunha, Renisson Neponuceno de Araújo Filho","doi":"10.28951/rbb.v38i1.427","DOIUrl":"https://doi.org/10.28951/rbb.v38i1.427","url":null,"abstract":"§ ABSTRACT: In population genetics, it is very common to use statistical analysis to test the Hardy-Weinberg genetic equilibrium in a given population. The classical method of approaching this problem is done through the chi-square test that often leads to the verification of the equilibrium hypothesis. In the present work, a Bayesian analysis was developed involving hypothesis testing, estimation and credibility intervals to test this balance. Data on M, MN and N blood groups from the MNS system were used on samples from two populations, one from Brazilians and one from North Americans, obtained by Beiguelman (1977). The HardyWeinberg equilibrium adhesion chi-square test was performed, where the acceptance of the Hardy-Weinberg equilibrium hypothesis was confirmed. By Bayesian analysis, the rejection of the Hardy-Weinberg equilibrium hypothesis was confirmed, mainly by the Bayes factor. Our primary concern was to develop a Bayesian technique as an alternative to testing HardyWeinberg equilibrium using the MNSs blood sample data. The result obtained may encourage researchers mainly in the field of biological sciences to practice Bayesian Methodology, as an alternative in statistical tests.","PeriodicalId":36293,"journal":{"name":"Revista Brasileira de Biometria","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90644771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"ESTIMAÇÃO DE RATING NO FUTEBOL: CAMPEONATO BRASILEIRO DE 2017","authors":"L. Galvão, J. S. D. S. B. Filho","doi":"10.28951/RBB.V38I1.403","DOIUrl":"https://doi.org/10.28951/RBB.V38I1.403","url":null,"abstract":"","PeriodicalId":36293,"journal":{"name":"Revista Brasileira de Biometria","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89244376","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R. C. Guarçoni, Fabiano Tristão Alixandre, D. G. Sousa, L. L. Pereira, Dério Brioschi Junior, Luiz Henrique Bozzi Pimenta de Sousa, L. Favarato, João Paulo Pereira Marcate
§ ABSTRACT: Coffee cultivation is of great socioeconomic importance for the Espírito Santo State, generating, in addition to direct and indirect jobs, financial resources. According to the first survey of the 2019 crop of CONAB, it is expected a production between 12.5 to 14.7 million of benefited bags. Research on coffee cultivation has contributed to the development of new technologies, but the size of plots for experiments with coffee is variable and based mostly on the researcher's experience. Thus, the objective of this work was to determine the optimal sizes of experimental plots to evaluate the pre-harvest, production and sensory characteristics of arabica coffee. The modeling applied in this study allows concluding that according to the data tested, it is possible to recommend the optimum size of experimental plots for arabica coffee, for these edaphoclimatic conditions and variety. The conclusions are as follows: it is recommended to use seven or more arabica coffee plants to evaluate the pre-harvest and harvest characteristics (plant height, plant diameter, vigor, and wet mass), and use, at least, seven plants of arabica coffee to evaluate sensory characteristics (fragrance, flavor, aftertaste, acidity, body, uniformity, balance, clean cup, sweetness, overall, and total score). §
{"title":"PLOT SIZE FOR EVALUATION OF AGRONOMIC AND SENSORIAL CHARACTERISTICS OF ARABICA COFFEE","authors":"R. C. Guarçoni, Fabiano Tristão Alixandre, D. G. Sousa, L. L. Pereira, Dério Brioschi Junior, Luiz Henrique Bozzi Pimenta de Sousa, L. Favarato, João Paulo Pereira Marcate","doi":"10.28951/rbb.v38i1.426","DOIUrl":"https://doi.org/10.28951/rbb.v38i1.426","url":null,"abstract":"§ ABSTRACT: Coffee cultivation is of great socioeconomic importance for the Espírito Santo State, generating, in addition to direct and indirect jobs, financial resources. According to the first survey of the 2019 crop of CONAB, it is expected a production between 12.5 to 14.7 million of benefited bags. Research on coffee cultivation has contributed to the development of new technologies, but the size of plots for experiments with coffee is variable and based mostly on the researcher's experience. Thus, the objective of this work was to determine the optimal sizes of experimental plots to evaluate the pre-harvest, production and sensory characteristics of arabica coffee. The modeling applied in this study allows concluding that according to the data tested, it is possible to recommend the optimum size of experimental plots for arabica coffee, for these edaphoclimatic conditions and variety. The conclusions are as follows: it is recommended to use seven or more arabica coffee plants to evaluate the pre-harvest and harvest characteristics (plant height, plant diameter, vigor, and wet mass), and use, at least, seven plants of arabica coffee to evaluate sensory characteristics (fragrance, flavor, aftertaste, acidity, body, uniformity, balance, clean cup, sweetness, overall, and total score). §","PeriodicalId":36293,"journal":{"name":"Revista Brasileira de Biometria","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87437439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
§ RESUMO: Pesquisas são necessárias para subsidiar os silvicultores à manejarem a floresta visando melhor aproveitamento. Para auxiliar as pesquisas pode-se, analisando a distribuição diamétrica, agrupar as espécies de acordo com as suas características em relação ao crescimento diamétrico e projetar o seu crescimento futuro, determinando se atingiu o diâmetro esperado antes do ciclo de corte estipulado em lei. O trabalho teve como objetivo realizar a prognose da distribuição diamétrica da floresta utilizando o modelo Matriz de Transição para as espécies classificadas como tolerantes, intolerantes e intermediárias e definir o ciclo de corte por grupos ecológicos, a fim de verificar se o tempo definido na legislação ambiental brasileira é compatível com a recuperação e crescimento das espécies arbóreas. A área da pesquisa localiza-se em Moju, Pará-Brasil. Selecionou-se 9 clareiras, em torno das quais instalou-se 4 parcelas amostrais de 500 m2. Foram medidos todos os indivíduos com DAP ≥ 5 cm. Para a prognose, utilizou-se os dados reais dos anos 2007 e 2010 e fez-se as projeções para períodos de 3 anos (2013 a 2028). Com os dados prognosticados fez-se a estimativa do volume até 31 anos após exploração florestal. Constatou-se que para as espécies tolerantes e intolerantes o ciclo de corte ideal é de 16 anos e para as intermediárias é de 22 anos. § PALAVRAS-CHAVE: Exploração florestal; manejo florestal; matriz de transição; distribuição diamétrica.
摘要:需要进行研究，以补贴护林员管理森林，以更好地利用森林。为了帮助研究，可以分析直径分布，根据物种的直径生长特征对它们进行分组，并预测它们未来的生长，确定在法律规定的切割周期之前是否达到了预期的直径。工作目标实现的预测分布diamétrica森林物种分类的过渡矩阵模型的宽容,宽容和中间设置周期的生态的小组,以确保巴西环境立法的规定时间符合经济复苏和增长的树种。研究区域位于Moju, para - brazil。选取9个林分，在林分周围设置4个500平方米的样地。测量胸径≥5 cm的所有个体。在预测方面，我们使用了2007年和2010年的实际数据，并对3年(2013年至2028年)进行了预测。根据预测数据，估计了森林开发后31年的产量。结果表明，耐受和不耐受物种的理想切割周期为16年，中间物种的理想切割周期为22年。§关键词:林业;林业管理;过渡矩阵;diamétrica分布。
{"title":"PREDIÇÃO DO CICLO DE CORTE DE ESPÉCIES ARBÓREAS COMERCIAIS POR GRUPOS ECOLÓGICOS EM UMA FLORESTA NA AMAZÔNIA BRASILEIRA","authors":"L. C. Oliveira, F. Jardim, J. M. Gomes","doi":"10.28951/rbb.v38i1.412","DOIUrl":"https://doi.org/10.28951/rbb.v38i1.412","url":null,"abstract":"§ RESUMO: Pesquisas são necessárias para subsidiar os silvicultores à manejarem a floresta visando melhor aproveitamento. Para auxiliar as pesquisas pode-se, analisando a distribuição diamétrica, agrupar as espécies de acordo com as suas características em relação ao crescimento diamétrico e projetar o seu crescimento futuro, determinando se atingiu o diâmetro esperado antes do ciclo de corte estipulado em lei. O trabalho teve como objetivo realizar a prognose da distribuição diamétrica da floresta utilizando o modelo Matriz de Transição para as espécies classificadas como tolerantes, intolerantes e intermediárias e definir o ciclo de corte por grupos ecológicos, a fim de verificar se o tempo definido na legislação ambiental brasileira é compatível com a recuperação e crescimento das espécies arbóreas. A área da pesquisa localiza-se em Moju, Pará-Brasil. Selecionou-se 9 clareiras, em torno das quais instalou-se 4 parcelas amostrais de 500 m2. Foram medidos todos os indivíduos com DAP ≥ 5 cm. Para a prognose, utilizou-se os dados reais dos anos 2007 e 2010 e fez-se as projeções para períodos de 3 anos (2013 a 2028). Com os dados prognosticados fez-se a estimativa do volume até 31 anos após exploração florestal. Constatou-se que para as espécies tolerantes e intolerantes o ciclo de corte ideal é de 16 anos e para as intermediárias é de 22 anos. § PALAVRAS-CHAVE: Exploração florestal; manejo florestal; matriz de transição; distribuição diamétrica.","PeriodicalId":36293,"journal":{"name":"Revista Brasileira de Biometria","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78647102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Exact d-optimal design under response variable transformation","authors":"C. Reis, L. Trinca","doi":"10.28951/rbb.v38i2.443","DOIUrl":"https://doi.org/10.28951/rbb.v38i2.443","url":null,"abstract":"","PeriodicalId":36293,"journal":{"name":"Revista Brasileira de Biometria","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84098713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
This paper presents a special capability of Sisvar to deal with fixed effect models with several restriction in the randomization procedure. These restrictions lead to models with fixed treatment effects, but with several random errors. One way do deal with models of this kind is to perform a mixed model analysis, considering only the error effects in the model as random effects and with different covariance structure for the error terms. Another way is to perform a analysis of variance with several error. These kind of analysis, when the data are balanced, can be done by using Sisvar. The software lead a exact $F$ test for the fixed effects and allow the user to applied multiple comparison procedures or regression analysis for the levels of the fixed effect factors, regarding they are single effects, interaction effects or hierarchical effects. Sisvar is an interesting statistical computer system for using in balanced agricultural and industrial data sets.
{"title":"SISVAR: A COMPUTER ANALYSIS SYSTEM TO FIXED EFFECTS SPLIT PLOT TYPE DESIGNS","authors":"D. F. Ferreira","doi":"10.28951/rbb.v37i4.450","DOIUrl":"https://doi.org/10.28951/rbb.v37i4.450","url":null,"abstract":"This paper presents a special capability of Sisvar to deal with fixed effect models with several restriction in the randomization procedure. These restrictions lead to models with fixed treatment effects, but with several random errors. One way do deal with models of this kind is to perform a mixed model analysis, considering only the error effects in the model as random effects and with different covariance structure for the error terms. Another way is to perform a analysis of variance with several error. These kind of analysis, when the data are balanced, can be done by using Sisvar. The software lead a exact $F$ test for the fixed effects and allow the user to applied multiple comparison procedures or regression analysis for the levels of the fixed effect factors, regarding they are single effects, interaction effects or hierarchical effects. Sisvar is an interesting statistical computer system for using in balanced agricultural and industrial data sets.","PeriodicalId":36293,"journal":{"name":"Revista Brasileira de Biometria","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88671518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Information from the population should be directly transposed to the individual level only under strict conditions of stationarity and homogeneity. In general, psychological phenomena are neither stationary nor homogeneous. Furthermore, the individual parameters must be estimated. The usual techniques of estimating the individual are rarely attainable. This occurs because in order to get valid estimates of individual parameters, many occasions of the same test must be performed. In this article, we propose an approach (simerg algorithm) to estimate the individual, so that a proper clinical testing for the individual in the context of testing setting that require the respondents’ performance becomes viable. We present the rationale of simerg and apply it to estimate the verbal comprehension ability of three individuals, which performed, in 90 different occasions, the 60 items of this ability. In this application, we show how simerg uses the initial empirical performance of these persons and simulates their whole performance. We evaluate the validity of simerg using different measures to predict the empirical performance. We conclude that simerg produces valid estimates. Further studies in a variety of populations and tests that require respondents’ performance are needed to enable a stronger conclusion about the validity of simerg.
{"title":"PROPOSING AN ACHIEVEMENT SIMULATION METHODOLOGY TO ALLOW THE ESTIMATION OF INDIVIDUAL IN CLINICAL TESTING CONTEXT","authors":"E. Jelihovschi, C. Gomes","doi":"10.28951/rbb.v37i4.423","DOIUrl":"https://doi.org/10.28951/rbb.v37i4.423","url":null,"abstract":"Information from the population should be directly transposed to the individual level only under strict conditions of stationarity and homogeneity. In general, psychological phenomena are neither stationary nor homogeneous. Furthermore, the individual parameters must be estimated. The usual techniques of estimating the individual are rarely attainable. This occurs because in order to get valid estimates of individual parameters, many occasions of the same test must be performed. In this article, we propose an approach (simerg algorithm) to estimate the individual, so that a proper clinical testing for the individual in the context of testing setting that require the respondents’ performance becomes viable. We present the rationale of simerg and apply it to estimate the verbal comprehension ability of three individuals, which performed, in 90 different occasions, the 60 items of this ability. In this application, we show how simerg uses the initial empirical performance of these persons and simulates their whole performance. We evaluate the validity of simerg using different measures to predict the empirical performance. We conclude that simerg produces valid estimates. Further studies in a variety of populations and tests that require respondents’ performance are needed to enable a stronger conclusion about the validity of simerg.","PeriodicalId":36293,"journal":{"name":"Revista Brasileira de Biometria","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83264745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Leandro da Silva Pereira, L. Chaves, Devanil Jaques de Souza
The theory of model prediction error is presented in details from the point of view of geometric constructions. It is expected that this approach can be a possible pedagogical tool in the treatment of the subject. Although the focus is essentially conceptual, all algebraic passages is developed in order to facilitate a greater understanding for the reader. Two elementary examples are presented.
{"title":"ON THE PREDICTION ERROR","authors":"Leandro da Silva Pereira, L. Chaves, Devanil Jaques de Souza","doi":"10.28951/rbb.v37i4.410","DOIUrl":"https://doi.org/10.28951/rbb.v37i4.410","url":null,"abstract":"The theory of model prediction error is presented in details from the point of view of geometric constructions. It is expected that this approach can be a possible pedagogical tool in the treatment of the subject. Although the focus is essentially conceptual, all algebraic passages is developed in order to facilitate a greater understanding for the reader. Two elementary examples are presented.","PeriodicalId":36293,"journal":{"name":"Revista Brasileira de Biometria","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77595145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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