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Challenges of surgical techniques improvement for abdominal hernia and repair materials development to hernia surgery 腹疝手术技术改进的挑战及腹疝手术修复材料的发展
Q4 Medicine Pub Date : 2019-11-20 DOI: 10.3760/CMA.J.ISSN.1673-9752.2019.11.001
Jianxiong Tang
The purpose of hernioplasty is to repair defects and restore abdominal wall function, and ultimately to improve the quality of patients′ life. With the innovation of basic theories, anatomical concepts, surgical techniques and repair materials, hernioplasty has made tremendous progress, but its basic principles of treatment have not changed. In recent 20 years, hernia surgery in China has entered a period of comprehensive and rapid development, showing a leap in the level of diagnosis and treatment, surgical technology, the number of operations and other aspects. Meanwhile, a series of clinical quality control systems, such as training, registration and adverse event monitoring, have been established, making China the top level of the world as a whole. At present, the surgical methods of abdominal wall hernia are flourishing and developing rapidly. The application of different levels, different approaches and different materials in the treatment of individualized patients has shown good clinical results. Of course, there is no repair material that meets the requirements of "ideal patch" . Although the implantation of synthetic materials has greatly improved the clinical effect of hernia, the permanent presence of foreign materials also brings about the possibility of long-term complications. A series of absorbable materials represented by "tissue-induced biomaterials" are closer to human tissues, which may represent the direction of the development of hernia repair materials, but long-term follow-up results are still needed to confirm their clinical efficacy. Key words: Hernia; Abdominal hernia; Surgery; Materialogy
疝修补术的目的是修复腹壁缺损,恢复腹壁功能,最终提高患者的生活质量。随着基础理论、解剖学观念、手术技术和修补材料的创新,疝成形术取得了巨大的进步,但其治疗的基本原则并没有改变。近20年来,中国疝外科进入了全面快速发展的时期,在诊疗水平、手术技术、手术数量等方面都出现了飞跃。同时,建立了培训、注册、不良事件监测等一系列临床质量控制体系,使中国整体处于世界一流水平。目前,腹壁疝的手术治疗方法蓬勃发展。不同层次、不同途径、不同材料在个体化患者治疗中的应用取得了良好的临床效果。当然,没有一种修补材料符合“理想补片”的要求。虽然人工合成材料的植入大大提高了疝的临床疗效,但异物的永久存在也带来了长期并发症的可能。以“组织诱导生物材料”为代表的一系列可吸收材料更接近人体组织,这可能代表了疝修补材料的发展方向,但其临床疗效仍需要长期随访结果来证实。关键词:疝;腹部疝;手术;外延
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引用次数: 0
Efficacy and safety of enhanced recovery after surgery in perioperative management of pancreatoduo-denectomy: a Meta analysis 胰双胰切除术围手术期治疗中增强术后恢复的有效性和安全性:一项Meta分析
Q4 Medicine Pub Date : 2019-11-20 DOI: 10.3760/CMA.J.ISSN.1673-9752.2019.11.012
X. Shao, Jin Gu, Yongkang Zou, Yu Cao, Kui Tu, Lijin Zhao
Objective To systematically evaluate the efficacy and safety of enhanced recovery after surgery (ERAS) in perioperative management of pancreatoduodenectomy. Methods Literatures were researched using the Cochrane Library, PubMed, Embase, CNKI, VANFUN database, CBM, China Science and Technology Journal Database from June 1979 to June 2019 with the key words including "enhanced recovery after surgery, fast-track surgery, fast track multi-disciplinary treatment, pancreatoduodenectomy, laparoscopic pancreatoduodenectomy, whipple surgery, 加速康复外科, 快速康复外科, 加速康复综合治疗模式, 胰十二指肠切除术, 腹腔镜胰十二指肠切除术, whipple手术" . The randomized controlled trial or prospective cohort study about traditional perioperative management versus ERAS in perioperative management of pancreatico-duodenectomy were received and enrolled. The patients receiving ERAS in perioperative management and traditional perioperative management were respectively allocated into ERAS group and control group. Two reviewers independently screened literatures, extracted data and assessed the risk of bias. Count data were described as risk ratio (RR) and 95% confidence interval (CI). Measurement data were represented as mean difference (MD) and 95%CI. The heterogeneity of the studies was analyzed using the I2 test. Funnel plot was used to test potential publication bias if the studies included ≥ 5, and no test was needed if the studies included < 5. Results (1) Document retrieval: a total of 8 randomized controlled trials were included. There were 1 187 patients, including 588 in the ERAS group and 599 in the control group. (2) Results of Meta analysis. ① There was no significant difference in the incidence of postoperative hemorrhage between the two groups (RR=0.79, 95%CI: 0.45-1.37, P>0.05). The bilateral symmetry was presented in the funnel plot based on the 8 studies, suggesting that publication bias had little influence on results of Meta analysis. ② There was no significant difference in the incidence of postoperative pancreatic fistula between the two groups (RR=0.97, 95%CI: 0.67-1.39, P>0.05). ③ There was no significant difference in the incidence of postoperative intra-abdominal infection between the two groups (RR=0.76, 95%CI: 0.51-1.12, P>0.05). The bilateral symmetry was presented in the funnel plot based on the 5 studies, suggesting that publication bias had little influence on results of Meta analysis. ④ There was a significant difference in the incidence of postoperative delayed gastric emptying between the two groups (RR=0.46, 95%CI: 0.31-0.67, P 0.05). The left-right asymmetry was presented in the funnel plot based on the 5 studies, suggesting that publication bias may exist in the included studies. Conclusion ERAS in the perioperative management of pancreatoduodenectomy is safe and effective, which can reduce the incidence of postoperative delayed gastric emptying, shorten the time to postoperative first flatus and duration of hospital stay, and reduce the incidence of posto
目的系统评价术后强化恢复(ERAS)在胰十二指肠切除术围手术期管理中的有效性和安全性。方法利用Cochrane图书馆、PubMed、Embase、CNKI、VANFUN数据库、CBM、中国科技期刊数据库对1979年6月至2019年6月的文献进行检索,检索关键词为“术后恢复增强、快速通道手术、多学科快速通道治疗、胰十二指肠切除术、,加速康复外科, 快速康复外科, 加速康复综合治疗模式, 胰十二指肠切除术, 腹腔镜胰十二指肠切除术, 鞭状物手术“.接受并纳入了关于传统围手术期管理与ERAS在胰十二指肠切除术围手术期处理中的随机对照试验或前瞻性队列研究。接受ERAS围手术期治疗和传统围术期管理的患者分别被分为ERAS组和对照组。两名评审员独立筛选文献,提取数据并评估偏倚的风险。计数数据描述为风险比(RR)和95%置信区间(CI)。测量数据用平均差(MD)和95%置信区间表示。使用I2检验分析研究的异质性。如果研究包括≥5项,则使用漏斗图来测试潜在的发表偏倚,如果研究包括<5项,则不需要测试。结果(1)文献检索:共纳入8项随机对照试验。共有1187例患者,其中ERAS组588例,对照组599例。(2) Meta分析结果。①两组术后出血发生率无显著性差异(RR=0.79,95%CI:0.45-1.37,P>0.05)。8项研究的漏斗图显示双侧对称性,表明发表偏倚对Meta分析结果影响不大。②两组术后胰瘘发生率无显著差异(RR=0.97,95%CI:0.67-139,P>0.05),提示发表偏倚对Meta分析结果影响不大。④两组术后胃排空延迟的发生率有显著差异(RR=0.46,95%CI:0.31-0.67,P 0.05)。基于5项研究,漏斗图显示左右不对称,表明纳入研究中可能存在发表偏倚。结论ERAS在胰十二指肠切除术围手术期管理中是安全有效的,可降低术后胃排空延迟的发生率,缩短术后首次排气时间和住院时间,降低术后综合并发症的发生率。关键词:术后恢复增强;胰十二指肠切除术;功效;安全;随机对照试验;Meta分析
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引用次数: 0
Endoscopic totally visceral sac separation: a novel concept for ventral hernia 内镜下完全内脏囊分离:一种治疗腹疝的新概念
Q4 Medicine Pub Date : 2019-11-20 DOI: 10.3760/CMA.J.ISSN.1673-9752.2019.11.005
Binggen Li
The whole abdominal wall can be regarded as a physiological and functional entity which is composed of multiple anatomical structures and layers. Surgical approaches or techniques are differently required for different portions of the abdominal wall. Indeed, the abdominal wall is confined by several anatomical boundaries which make different surgical spaces disconnected. If these boundaries could be broken down, separated spaces are now connected, establishing an ample retromuscular/preperitoneal space to perform totally visceral sac separation. The author has investigated the anatomical portions, significance of abdominal wall in totally visceral sac separation, and technical details and notes of totally visceral sac separation for different portions of abdominal wall in this paper. Key words: Hernia; Ventral hernia; Endoscopy; Totally visceral sac separation; Tension free repair; Extraperitoneal; Retromuscular repair; Laparoscopy
整个腹壁可以看作是一个由多个解剖结构和层次组成的生理和功能实体。对于腹壁的不同部分需要不同的手术方法或技术。事实上,腹壁受到几个解剖边界的限制,这些边界使不同的手术空间断开。如果这些边界可以被打破,那么分离的空间现在就被连接起来,建立一个充足的肌后/腹膜前空间来进行完全的内脏囊分离。本文研究了腹壁的解剖部位、腹壁在全脏囊分离中的意义,以及腹壁不同部位全脏囊的分离技术细节和注意事项。关键词:疝;腹疝;内窥镜;完全内脏囊分离;无张力修复;腹膜外;肌后修复;腹腔镜检查
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引用次数: 0
The differences and characteristics of radical resection for rectal cancer between China and Japan by the conference of "Chinese and Japanese gastroenteral standard interpretation meeting on neuroprotection and lymph node dissection by 4K" 从“中日胃肠神经保护及4K淋巴结清扫标准解读会”会议看中日直肠癌根治术的差异及特点
Q4 Medicine Pub Date : 2019-11-20 DOI: 10.3760/CMA.J.ISSN.1673-9752.2019.11.102
Yonghong Dong, Y. Kuang, Tong-Gang Qi, Jiguang Xie, Jun Xu
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引用次数: 0
Clinical application value of abdominal incisional hernia repair 腹壁切口疝修补术的临床应用价值
Q4 Medicine Pub Date : 2019-11-20 DOI: 10.3760/CMA.J.ISSN.1673-9752.2019.11.007
Kai Min, Jun Ren, Biao Wu, Chunxiong Zhao, Chenxia Wang, Hua-tao Chen, Xiaohui Li, X. Xiao, Jianhui Guo
Objective To investigate the clinical application value of abdominal incisional hernia repair. Methods The retrospective and descriptive study was conducted. The clinical data of 104 patients who underwent abdominal incisional hernia repair in the Wuhan No.1 Hospital from January 2013 to December 2017 were collected. There were 38 males and 66 females, aged (58±4)years, with a range from 31 to 85 years. All patients underwent abdominal incisional hernia repair by patch implantation. Observation indicators: (1) intraoperative conditions; (2) complications; (3) follow-up. Follow-up by telephone questionnaires was performed to detect the postoperative recurrence up to June 2019. Measurement data with normal distribution were expressed as Mean±SD, measurement data with skewed distribution were expressed as M (P25, P75), and count data were expressed as absolute numbers. Results (1) Intraoperative conditions: all the 104 patients underwent the abdominal incisional hernia repair successfully. The operation time, duration of postoperative hospital stay were (111±18)minutes and (6.1±2.4)days. Among the 104 patients, 29 underwent open surgery, 38 underwent laparoscopic surgery, and 37 underwent hybrid surgery. Among the 29 patients undergoing open surgery, 25 had defect area in the subumbilical region (M4 type), 2 had defect area in the hypochondrial region (L2 type), and 2 had defect area in the ilium region (L3 type); all patients had patches placed in posterior muscle space. Among the 38 patients undergoing laparoscopic surgery, 9 had subxiphoid defects (M1 type), 23 had epigastric defects (M2 type), and 6 had subcostal defects (L1 type); all patients had patches placed in intraperitoneal cavity. Among the 37 patients undergoing hybrid surgery, 27 had umbilical defects (M3 type) and 10 had suprapubic defects (M5 type); all patients had patches placed in intraperitoneal cavity. (2) Complications: among the 29 patients undergoing open surgery, 7 had complications, including 4 of pain in the repaired area of abdominal wall, 1 of poor wound healing, and 2 of seroma in the repaired area. Among the 38 patients undergoing laparoscopic surgery, 2 were suffered from pain in the repaired area of abdominal wall. Among the 37 patients undergoing hybrid surgery, 6 had complications, including 2 of poor wound healing and 4 of seroma in the repair area. Among the 104 patients, 6 patients with pain in the repair area of abdominal wall after operation were improved by local closure and analgesic treatment; 3 patients of poor wound healing were healed well after local dressing change and secondary debridement and suture; 6 patients with seroma in the repaired area were cured by puncture, drainage and pressure bandage. No intestinal fistula, intestinal obstruction, abdominal compartment syndrome or death occurred. (3)Follow-up: 104 patients were followed up for 13 months (3 months, 24 months). Among the 104 patients, 1 recurred at 6 months, 13 months and 16
目的探讨腹壁切口疝修补术的临床应用价值。方法采用回顾性和描述性研究。收集2013年1月至2017年12月在武汉市第一医院接受腹部切口疝修补术的104例患者的临床资料。男38例,女66例,年龄(58±4)岁,年龄31~85岁。所有患者均接受了疝修补术。观察指标:(1)术中情况;(2) 并发症;(3) 后续行动。通过电话问卷进行随访,以检测截至2019年6月的术后复发情况。正态分布的测量数据表示为Mean±SD,偏态分布的数据表示为M(P25,P75),计数数据表示为绝对数。结果(1)术中情况:104例患者均成功进行了腹壁切口疝修补术。手术时间、术后住院时间分别为(111±18)分钟和(6.1±2.4)天。104例患者中,29例接受了开放手术,38例接受了腹腔镜手术,37例接受了混合手术。在接受开放手术的29名患者中,25名患者的脐下区域有缺损区(M4型),2名患者的疑病症区域有缺损(L2型),还有2名患者在髂骨区域有缺损区域(L3型);所有患者均在后部肌肉间隙放置贴片。38例腹腔镜手术患者中,9例为剑突下缺损(M1型),23例为上腹部缺损(M2型),6例为肋下缺损(L1型);所有患者均在腹腔内放置贴片。在37例接受混合手术的患者中,27例为脐带缺损(M3型),10例为耻骨上缺损(M5型);所有患者均在腹腔内放置贴片。(2) 并发症:在29例接受开放手术的患者中,有7例出现并发症,其中4例为腹壁修复区疼痛,1例为伤口愈合不良,2例为修复区浆膜瘤。在接受腹腔镜手术的38名患者中,2名患者的腹壁修复区域疼痛。在接受混合手术的37名患者中,有6名出现并发症,其中2名伤口愈合不良,4名修复区浆膜瘤。104例患者中,6例术后腹壁修补区疼痛,经局部封闭及镇痛治疗后得到改善;3例创面愈合不良,经局部换药和二次清创缝合后,伤口愈合良好;修补区浆膜瘤6例,经穿刺、引流、加压包扎等方法治愈。未发生肠瘘、肠梗阻、腹腔综合征或死亡。(3) 随访:104例患者随访13个月(3个月,24个月)。104例患者中,1例分别在术后6个月、13个月和16个月复发。3例患者全部康复出院。结论腹壁切口疝修补术安全有效,应根据手术的具体情况进行选择。关键词:疝;腹部切口疝;修复手术;打开;杂交;临床应用;腹腔镜检查
{"title":"Clinical application value of abdominal incisional hernia repair","authors":"Kai Min, Jun Ren, Biao Wu, Chunxiong Zhao, Chenxia Wang, Hua-tao Chen, Xiaohui Li, X. Xiao, Jianhui Guo","doi":"10.3760/CMA.J.ISSN.1673-9752.2019.11.007","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1673-9752.2019.11.007","url":null,"abstract":"Objective \u0000To investigate the clinical application value of abdominal incisional hernia repair. \u0000 \u0000 \u0000Methods \u0000The retrospective and descriptive study was conducted. The clinical data of 104 patients who underwent abdominal incisional hernia repair in the Wuhan No.1 Hospital from January 2013 to December 2017 were collected. There were 38 males and 66 females, aged (58±4)years, with a range from 31 to 85 years. All patients underwent abdominal incisional hernia repair by patch implantation. Observation indicators: (1) intraoperative conditions; (2) complications; (3) follow-up. Follow-up by telephone questionnaires was performed to detect the postoperative recurrence up to June 2019. Measurement data with normal distribution were expressed as Mean±SD, measurement data with skewed distribution were expressed as M (P25, P75), and count data were expressed as absolute numbers. \u0000 \u0000 \u0000Results \u0000(1) Intraoperative conditions: all the 104 patients underwent the abdominal incisional hernia repair successfully. The operation time, duration of postoperative hospital stay were (111±18)minutes and (6.1±2.4)days. Among the 104 patients, 29 underwent open surgery, 38 underwent laparoscopic surgery, and 37 underwent hybrid surgery. Among the 29 patients undergoing open surgery, 25 had defect area in the subumbilical region (M4 type), 2 had defect area in the hypochondrial region (L2 type), and 2 had defect area in the ilium region (L3 type); all patients had patches placed in posterior muscle space. Among the 38 patients undergoing laparoscopic surgery, 9 had subxiphoid defects (M1 type), 23 had epigastric defects (M2 type), and 6 had subcostal defects (L1 type); all patients had patches placed in intraperitoneal cavity. Among the 37 patients undergoing hybrid surgery, 27 had umbilical defects (M3 type) and 10 had suprapubic defects (M5 type); all patients had patches placed in intraperitoneal cavity. (2) Complications: among the 29 patients undergoing open surgery, 7 had complications, including 4 of pain in the repaired area of abdominal wall, 1 of poor wound healing, and 2 of seroma in the repaired area. Among the 38 patients undergoing laparoscopic surgery, 2 were suffered from pain in the repaired area of abdominal wall. Among the 37 patients undergoing hybrid surgery, 6 had complications, including 2 of poor wound healing and 4 of seroma in the repair area. Among the 104 patients, 6 patients with pain in the repair area of abdominal wall after operation were improved by local closure and analgesic treatment; 3 patients of poor wound healing were healed well after local dressing change and secondary debridement and suture; 6 patients with seroma in the repaired area were cured by puncture, drainage and pressure bandage. No intestinal fistula, intestinal obstruction, abdominal compartment syndrome or death occurred. (3)Follow-up: 104 patients were followed up for 13 months (3 months, 24 months). Among the 104 patients, 1 recurred at 6 months, 13 months and 16 ","PeriodicalId":36400,"journal":{"name":"中华消化外科杂志","volume":"18 1","pages":"1032-1036"},"PeriodicalIF":0.0,"publicationDate":"2019-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48268508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical significance of anterior abdominal wall fascial in totally extraperitoneal herniorraphy 腹壁前筋膜在全腹膜外疝切开术中的临床意义
Q4 Medicine Pub Date : 2019-11-20 DOI: 10.3760/CMA.J.ISSN.1673-9752.2019.11.004
Jian-wen Li
All fascia between the transversalis fascia of anterior abdominal wall and the peritoneum can be called the preperitoneal fascia clinically. According to the interfascial plane theory, the preperitoneal fascia is a multi-layer structure, and preperitoneal space was divided into two surgical planes including parietal and visceral by its membrane layers. Surgical planes of totally extraperitoneal herniorraphy (TEP) can be described as follow: for median region, surgery can be performed in parietal plane, that is avascular region filled with loose areolar tissues between the transversalis fascia and the preperitoneal fascia, which is called "holy plane" of TEP. For Doom region, surgery is transferred into viscecal plane, which is between the preperitoneal fascia and the peritoneum, due to the particularity of spermatic cord through the abdominal wall. For lateral region, the abdominal wall restores to normal structure, and surgery can be performed in parietal plane or viscecal plane. The preperitoneal fascia needs to be dissected during the transfer from parietal plane to viscecal plane. The concept of plane transformation can explain the formation mechanism of preperitoneal loop and no connection between Reztius space and Bogros space. The author has elucidated the significance of preperitoneal fascial anatomy of anterior abdominal wall in TEP based on clinical experience of TEP and authoritative literatures. Key words: Hernia; Laparoscopy; Inguinal hernia; Membrane anatomy
腹壁横筋膜与腹膜之间的筋膜,临床均称为腹膜前筋膜。根据筋膜间平面理论,腹膜前筋膜是一个多层结构,腹膜前间隙按其膜层划分为壁层和内脏层两个手术平面。全腹膜外疝修补术(TEP)的手术平面可以描述为:对于正中区,可以在顶平面进行手术,即腹横筋膜与腹膜前筋膜之间充满疏松网状组织的无血管区域,称为TEP的“神圣平面”。对于Doom区,由于精索穿过腹壁的特殊性,手术转移到位于腹膜前筋膜和腹膜之间的内脏平面。对于外侧区,腹壁恢复到正常结构,手术可在壁平面或内脏平面进行。腹膜前筋膜在从壁平面转移到内脏平面的过程中需要被剥离。平面变换的概念可以解释腹膜前袢的形成机制,而Reztius空间与Bogros空间之间没有联系。笔者结合TEP的临床经验和权威文献,阐述了前腹壁腹膜前筋膜解剖在TEP中的意义。关键词:疝;腹腔镜检查;腹股沟疝;膜结构
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引用次数: 0
Effects of CT examination in different body positions on the evaluation of abdominal incisional hernia volume 不同体位CT检查对评价腹壁切口疝容量的影响
Q4 Medicine Pub Date : 2019-11-20 DOI: 10.3760/CMA.J.ISSN.1673-9752.2019.11.014
Z. Hou, Zhi-peng Jiang, Wenli Li, Wei Liu, Ying-ru Li, Taicheng Zhou, W. Gan, Shuang Chen
Objective To investigate the effects of computed tomography (CT) examination in different body positions on the evaluation of abdominal incisional hernia volume. Methods The retrospective case-control study was conducted. The clinical data of 23 patients with abdominal incisional hernia who were admitted to the Sixth Affiliated Hospital of Sun Yat-sen University from February to September in 2017 were collected. There were 14 males and 9 females, aged from 47 to 75 years, with an average age of 63 years. All patients underwent CT scan in supine position and lateral position. The volume of hernia sac, abdominal cavity and the volume ratio of hernia sac to abdominal cavity in different body positions were measured by multi-planar reconstruction and volume reappearance on the workstation. Observation indicators: (1) situations of CT examination of patients with abdominal incisional hernia in different positions; (2) correlation analysis of volume ratio increment of hernia sac to abdominal cavity between different positions by CT examination in patients with abdominal incisional hernia. Measurement data with normal distribution were expressed as Mean±SD, and comparison between groups was performed using the pared t test. Count data were expressed as absolute numbers or percentages. Pearson correlation was used to analyze the volume ratio increment of hernia sac to abdominal cavity between different positions by CT examination in patients with abdominal incisional hernia. Results (1) Situations of CT examination of patients with abdominal incisional hernia in different positions: CT examination of 23 patients with abdominal incisional hernia showed that the contents of hernia increased and the abdominal wall deformed in the lateral position compared with conventional supine position, with manifestations as shortened abdominal transverse diameter and longer vertical diameter. The volume of the hernia sac in supine position and in lateral position by CT examination was (623±293)mL and (869±425)mL, respectively, showing a significant difference (t=-7.959, P<0.05). The volume of abdominal cavity in supine position and in lateral position by CT examination was (6 445±1 438)mL and (6 283±1 348)mL, respectively, showing a significant difference (t=2.762, P<0.05). The volume ratio of hernia sac to abdominal cavity in supine position and in lateral position by CT examination was 0.096±0.040 and 0.138±0.061, showing a significant difference (t=-8.093, P<0.05). The volume ratio of hernia sac to abdominal cavity in lateral position increased by 0.042 compared with that in supine position, with an increasing rate of 43.8%. All the 23 patients had volume ratio of hernia sac to abdominal cavity less than 20% in supine position by CT examination, however, 4 patients had volume ratio of hernia sac to abdominal cavity more than 20% in lateral position by CT examination. (2) Correlation analysis of volume ratio increment of hernia sac to abdominal cavity be
目的探讨不同体位的计算机断层扫描(CT)检查对评价腹部切口疝容量的影响。方法采用回顾性病例对照研究。收集中山大学附属第六医院2017年2月至9月收治的23例腹壁切口疝患者的临床资料。共有14名男性和9名女性,年龄从47岁到75岁,平均年龄为63岁。所有患者均采用仰卧位和侧卧位进行CT扫描。在工作站上通过多平面重建和体积再现测量不同体位的疝囊体积、腹腔体积以及疝囊与腹腔体积比。观察指标:(1)腹部切口疝不同部位CT检查情况;(2) 腹部切口疝CT检查不同位置疝囊与腹腔容积比增量的相关性分析。具有正态分布的测量数据表示为Mean±SD,并使用对比试验进行组间比较。计数数据用绝对数或百分比表示。应用Pearson相关分析腹部切口疝患者CT检查不同位置疝囊与腹腔容积比的增量。结果(1)不同体位腹部切口疝的CT检查情况:23例腹部切口疝患者的CT检查显示,与传统仰卧位相比,表现为腹部横径缩短、纵径延长。CT检查仰卧位和侧卧位疝囊容积分别为(623±293)mL和(869±425)mL,差异有统计学意义(t=-7.959,P<0.05),CT检查仰卧位和侧位疝囊与腹腔容积比分别为0.096±0.040和0.138±0.061,差异有统计学意义(t=-8.093,P<0.05),23例患者仰卧位疝囊与腹腔容积比均小于20%,而4例患者侧卧位疝囊和腹腔容积比大于20%。(2) 腹部切口疝患者CT检查不同位置疝囊与腹腔容积比增量的相关性分析:Pearson相关分析结果显示,CT检查仰卧位与侧卧位疝囊与腹膜容积比呈正相关(r=0.742,P<0.05)切口疝的体积受体位的影响。与仰卧位相比,侧位CT检查能更准确地反映腹壁切口疝。关键词:疝;切口疝;身体姿势;计算机断层扫描,X射线;疝囊容积;腹腔容积;体积比
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引用次数: 0
Clinical efficacy of laparoscopic transabdominal partial extraperitoneal technique for lower abdominal marginal hernia 腹腔镜经腹部分腹腔外技术治疗下腹部边缘疝的临床疗效观察
Q4 Medicine Pub Date : 2019-11-20 DOI: 10.3760/CMA.J.ISSN.1673-9752.2019.11.008
M. Pan, Heguang Huang, Yan-chang Chen, F. Lu, Xian-chao Lin, R. Lin, Yuanyuan Yang, Congfei Wang
Objective To investigate the clinical efficacy of laparoscopic transabdominal partial extraperitoneal technique (TAPE) for lower abdominal marginal hernia. Methods The retrospective and descriptive study was conducted. The clinical data of 58 patients with lower abdominal marginal hernia who were admitted to Fujian Medical University Union Hospital between January 2011 and June 2018 were collected. There were 15 males and 43 females, aged (65±11)years, with a range of 54-76 years. All patients underwent laparoscopic TAPE. Observation indicators: (1) intra- and post-operative situations; (2) follow-up. Follow-up using outpatient examination and telephone interview was performed to detect postoperative complications to August 2018. Measurement data with normal distribution were represented as Mean±SD and count data were expressed as absolute numbers. Results (1) Intra- and post-operative situations: 58 patients underwent successfully TAPE. Diameter of hernia ring was (7.0±2.9)cm. Six of 58 patients underwent hybrid surgery due to severe adhesion of the intestine and abdominal wall, and adhesion was separated by a small abdominal incision. Two patients with recurrent hernia underwent TAPE after removal of the old patch. One, 1, and 1 patient combined with left direct inguinal hernia, right indirect inguinal hernia, and right direct inguinal hernia had simultaneous repair during the operation. The operation time and volume of intraoperative blood loss were (153±46)minutes and (20±10)mL. Early ambulation was encouraged without the limitations of anesthesia. A liquid diet was begun at 24 hours, and a semi-liquid diet was begun at 48 hours after the operation. The duration of postoperative hospital stay were (3.8±1.1)days. Pressure dressing was routinely adapted till 3 months after the operation. (2) Follow-up: all patients were followed up for (22±19)months. Seven of 58 patients had postoperative complications. Among them, 3 patients with seroma were cured by fine needle aspiration and pressure bandaging, 2 with intestinal obstruction were cured by conservative treatment including fasting, gastrointestinal decompression, purgative enema, inhibition of secretion of digestive juices, and fluid infusion, 1 with Trocar hernia was cured by tension-free repair under general anesthesia and had no recurrence, 1 with wound infection was healed after anti-infection and dressing change treatment. There was no recurrence, patch infection, chronic pain, urinary frequency and urgency or other complications found in other patients. Conclusion TAPE is safe and effective for lower abdominal marginal hernia. Key words: Hernia; Marginal hernia; Incisional hernia; Complications; Preperitoneal; Hernia repair; Mesh repair; Laparoscopy
目的探讨腹腔镜经腹腹膜外部分疝修补术(TAPE)治疗下腹缘疝的临床疗效。方法采用回顾性和描述性研究。收集福建医科大学协和医院2011年1月至2018年6月收治的58例下腹缘疝患者的临床资料。男15例,女43例,年龄(65±11)岁,年龄54~76岁。所有患者均接受腹腔镜TAPE。观察指标:(1)术中、术后情况;(2) 后续行动。截至2018年8月,通过门诊检查和电话访谈进行了随访,以发现术后并发症。正态分布的测量数据表示为Mean±SD,计数数据表示为绝对数。结果(1)术中、术后情况:58例患者成功施行TAPE。疝环直径为(7.0±2.9)cm。58例患者中有6例因肠和腹壁严重粘连而接受了混合手术,并通过腹部小切口分离粘连。两名复发性疝患者在取出旧疝片后接受了TAPE。1例、1例和1例合并左侧腹股沟直疝、右侧腹股沟斜疝和右侧腹股沟直疝的患者在手术中同时进行了修补。手术时间和术中出血量分别为(153±46)分钟和(20±10)mL。在没有麻醉限制的情况下,鼓励早期行走。术后24小时开始流质饮食,48小时开始半流质饮食。术后住院时间为(3.8±1.1)天,术后3个月采用常规压力敷料。(2) 随访:所有患者均进行了(22±19)个月的随访。58例患者中有7例出现术后并发症。其中,3例浆膜瘤患者经细针抽吸和压力包扎治愈,2例肠梗阻患者经禁食、胃肠减压、通便灌肠、抑制消化液分泌和输液等保守治疗治愈,1例Trocar疝患者在全麻下经无张力修复治愈,无复发,1例创面感染经抗感染及换药治疗后痊愈。在其他患者中没有发现复发、贴片感染、慢性疼痛、尿频和尿急或其他并发症。结论TAPE治疗下腹缘疝安全有效。关键词:疝;边缘疝;切口疝;并发症;腹膜前;疝修补术;网状修复;腹腔镜检查
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引用次数: 0
Analysis of risk factors for appendicitis caused by incarcerated inguinal hernia in infants 婴幼儿嵌顿性腹股沟疝并发阑尾炎的危险因素分析
Q4 Medicine Pub Date : 2019-11-20 DOI: 10.3760/CMA.J.ISSN.1673-9752.2019.11.010
Linling Gui, W. Lu, Fuzhong Xing, Bidong Xiao, Xiaofeng Xiong, Lei Yu
Objective To investigate the risk factors for appendicitis caused by incarcerated inguinal hernia in infants. Methods The retrospective case-control study was conducted. The clinicopathological data of 371 infants with incarcerated inguinal hernia who were admitted to Wuhan Children′s Hospital of Tongji Medical College of Huazhong University of Science and Technology between January 2010 and December 2018 were collected. There were 256 males and 115 females, aged from 0 to 90 days, with an average age of 47 days. Observation indicators: (1) situations of incarcerated hernia; (2) surgical and postoperative recovery; (3) postoperative pathological examination; (4) analysis of risk factors for appendicitis caused by incarcerated inguinal hernia in infants. Measurement data with skewed distribution were described as M (range). Count data were expressed as absolute numbers. Univariate analysis was performed using the chi-square test. Multivariate analysis was performed using the Logistic regression model. Results (1) Situations of incarcerated hernia: of the 371 infants, 264 had bowel incarceration, 102 had ovarian incarceration, 2 had both bilateral ovarian and bowel incarceration, 1 had bilateral ovarian and womb incarcerated into one side, and 2 had Meckel′s diverticulums incarceration. Among the 264 infants with bowel incarceration, 29 had Amyand′s hernia, including 18 of ileocecal incarceration (3 with appendicitis) and 11 of pure appendix incarceration (10 with appendicitis). (2) Surgical and postoperative recovery: of the 29 infants with Amyand′s hernia, 10 underwent laparoscopic hernia sac high ligation and 19 underwent inguinal explorations, relaxation of hernia ring and then hernia sac high ligation. One infant undergoing laparoscopic hernia sac high ligation had pure appendix incarceration. It showed that chorda at the blind end of appendix was connected with the bottom of hernia sac intraoperatively. There was no obvious inflammation in the appendix. Chorda was released, and the appendix was reset into the abdominal cavity. One infant was resected appendix because of its inflammation after ileocecal reduction. Twelve infants undergoing inguinal explorations, relaxation of hernia ring and then hernia sac high ligation had appendicitis (2 of ileocecal incarceration and 10 of pure appendix incarceration), and received appendectomy and hernia sac high ligation. One infant of ileocecal incarceration had postoperative intestinal adhesion, and was found local adhesion and stenosis after abdominal re-exploration. The infant underwent ileocecoectomy followed by ileum-ascending colon anastomosis. All infants recovered well after operation. (3) Postoperative pathological examination: 13 of 29 Amyand′s hernia infants had appendictis, 4 of which were confirmed as appendix suppuration by pathological examination, 2 were appendix suppuration and perforation, and 2 were gangrene. (4) Analysis of risk factors for appendicitis caused by incarce
目的探讨婴幼儿嵌顿性腹股沟疝并发阑尾炎的危险因素。方法采用回顾性病例对照研究。收集华中科技大学同济医学院武汉儿童医院2010年1月至2018年12月收治的371例嵌顿性腹股沟疝患儿的临床病理数据。共有256名男性和115名女性,年龄从0到90天,平均年龄为47天。观察指标:(1)嵌顿性疝的情况;(2) 手术和术后恢复;(3) 术后病理检查;(4) 婴儿嵌顿性腹股沟疝引起阑尾炎的危险因素分析。具有偏斜分布的测量数据被描述为M(范围)。计数数据用绝对数表示。采用卡方检验进行单变量分析。采用Logistic回归模型进行多变量分析。结果(1)嵌顿疝情况:371例婴儿中,264例发生肠嵌顿,102例发生卵巢嵌顿,2例同时发生双侧卵巢和肠嵌顿、1例双侧卵巢和子宫嵌顿在一侧,2例发生Meckel′s憩室嵌顿。264例肠嵌顿患儿中,29例为Amyand疝,其中回盲部嵌顿患儿18例(3例为阑尾炎),单纯阑尾嵌顿患儿11例(10例为阑尾)。(2) 手术和术后恢复:在29例Amyand疝患儿中,10例接受了腹腔镜疝囊高位结扎术,19例接受了腹股沟探查术、疝环松弛术和疝囊高位扎合法。一名接受腹腔镜疝囊高位结扎术的婴儿出现单纯阑尾嵌顿。术中发现阑尾盲端脊索与疝囊底部相连。阑尾没有明显的炎症。脊索被释放,阑尾被重新植入腹腔。一名婴儿因回盲部缩小术后阑尾发炎而被切除。12名接受腹股沟探查、疝环松弛和疝囊高位结扎的婴儿患有阑尾炎(2例回盲部嵌顿,10例纯阑尾嵌顿),并接受了阑尾切除术和疝囊低位结扎术。1例回盲部嵌顿患儿术后出现肠粘连,腹部复查发现局部粘连狭窄。婴儿接受了回盲部切除术,然后进行回肠升结肠吻合术。所有婴儿术后恢复良好。(3) 术后病理检查:29例Amyand疝患儿中13例有阑尾,其中4例经病理检查证实为阑尾化脓,2例为阑尾化脓穿孔,2例坏疽。(4) 嵌顿性腹股沟疝引起阑尾炎的危险因素分析。单因素分析结果显示,年龄、阴囊局部肿胀和红斑、肠梗阻、嵌顿位置是嵌顿性腹股沟疝引起阑尾炎的相关因素(χ2=10.598、15.603、9.732、3.866,P<0.05),无明显梗阻是嵌顿性腹股沟疝引起阑尾炎的独立危险因素(优势比:4.537,35.506,34.565,95%可信区间:1.014-20.296,6.447-195.552,6.370-187.546,P<0.05),无明显梗阻是嵌顿性腹股沟疝引起阑尾炎的独立危险因素。关键词:疝;腹股沟疝;Amyand疝;阑尾炎;新生儿;风险因素
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引用次数: 0
Research progress in microsatellite instability and diagnosis and treatment of gallbladder cancer 微卫星不稳定性与胆囊癌诊治的研究进展
Q4 Medicine Pub Date : 2019-11-20 DOI: 10.3760/CMA.J.ISSN.1673-9752.2019.11.016
Qi Li, Chen Chen, Rui Zhang, Dong Zhang
Gallbladder cancer is a kind of common biliary tract tumor with high malignancy and poor prognosis. In recent years, many studies have shown that microsatellite instability (MSI) may be one of the mechanisms of gallbladder carcinogenesis. High frequency microsatellite instability (MSI-H) gallbladder cancer has a better therapeutic effect by treatment with an immunological checkpoint inhibitor due to its unique clinicopathological features. The general characteristics and the detection methods of MSI, clinicopathological features of gallbladder cancer, treatment of programmed cell death 1/programmed cell death ligand 1 immunological checkpoint inhibitors with MSI have been reviewed in this article. Key words: Biliary tract neoplasms, malignant; Gallbladder cancer; Microsatellite instability; Programmed cell death 1; Programmed cell death 1 ligand 1; Immunological checkpoint inhibitors
胆囊癌是一种常见的胆道肿瘤,恶性程度高,预后差。近年来,许多研究表明微卫星不稳定性(microsatellite instability, MSI)可能是胆囊癌变的机制之一。高频微卫星不稳定性(MSI-H)胆囊癌由于其独特的临床病理特点,采用免疫检查点抑制剂治疗具有较好的治疗效果。本文就MSI的一般特点、检测方法、胆囊癌的临床病理特点、MSI治疗程序性细胞死亡1/程序性细胞死亡配体1免疫检查点抑制剂等方面进行综述。关键词:胆道肿瘤;恶性;胆囊癌症;微卫星不稳定性;程序性细胞死亡1;程序性细胞死亡1配体1;免疫检查点抑制剂
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