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A single center experience in prevention and control of infection risk related to liver transplantation during the COVID-19 outbreak 新冠肺炎疫情期间单中心肝移植感染风险防控经验
Q4 Medicine Pub Date : 2020-01-01 DOI: 10.3760/cma.j.cn115610-20200402-00224
RenDong Liu, F. Huo, Shao-ping Wang, Yujian Zheng, Qing Ouyang, Bao Zhang, ZhiPing Cai
Objective: To investigate the clinical evaluation effects of Corona Virus Disease 2019 (COVID-19) risk assessment scale on preoperative and surgical risk of liver transplantation during the COVID-19 outbreak
目的:探讨2019冠状病毒病(COVID-19)风险评估量表对2019冠状病毒病(COVID-19)疫情期间肝移植术前和手术风险的临床评价效果
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引用次数: 0
Clinical efficacy of laparoscopic stomach intestinal pylorus sparing surgery in the treatment of severe obesity 腹腔镜胃幽门保留手术治疗重度肥胖的临床疗效观察
Q4 Medicine Pub Date : 2019-12-20 DOI: 10.3760/CMA.J.ISSN.1673-9752.2019.12.014
Lun Wang, Shixing Li, Yang Yu, Jinfa Wang, Yuhui Zhao, Linfeng Bai, Shu Chen
Objective To investigate the clinical efficacy of laparoscopic stomach intestinal pylorus sparing surgery (SIPS) in the treatment of severe obesity. Methods The retrospective and descriptive study was conducted. The clinical data of 5 patients with severe obesity who were admitted to the China-Japan Union Hospital Affiliated to Jilin University from October to November 2018 were collected. There was 1 male and 4 females, aged from 18 to 55 years, with an average age of 33 years. All the 5 patients underwent laparoscopic SIPS. Observation indicators: (1) surgical situations; (2) postoperative situations; (3) follow-up. Follow-up was performed by outpatient examination, telephone interview and Wechat up to February 2019, including general condition, changes in body weight, body mass index, waistline, blood pressure, percentage of excess weight loss, fasting plasma glucose, glycosylated hemoglobin, blood lipid, and uric acid at 3 months after surgery. Measurement data with normal distribution were represented as Mean±SD, and they were tested with Hotelling T2 test. Measurement data with skewed distribution were represented as M (range). Results (1) Surgical situations: 5 patients underwent successfully laparoscopic SIPS under clear surgical field, without obvious bleeding, conversion to open surgery or perioperative death. The operation time was 240 minutes (range, 165-345 minutes). (2) Postoperative situations: the time to initial out-of-bed activity, time to first and flatus, and time to initial drinking and liquid intake were 2 days (range, 2-3 days), 3 days (range, 2-3 days), and 3 days (range, 3-4 days), respectively. On the third day after surgery, all the 5 patients were confirmed anastomotic patency, without gastric leakage, stenosis, or obstruction by upper gastrointestinal contrast. The abdominal drainage-tube was removed on the fourth day after feeding without obvious discomfort and foreign substances extraction from the drainage-tube. The duration of postoperative hospital stay was 6 days (range, 6-7 days). (3) Follow-up: 5 patients with severe obesity were successfully followed up for 3 months. During the follow-up, one patient had significantly increased frequency of defecation, roughly 5-8 times a day, especially after eating greasy food. According to the dietary guidance of the case manager, diarrhea was improved significantly after reducing the intake of oily food. Of the 5 patients with severe obesity, color doppler ultrasonography examination revealed that cholestasis was found in 2 patients at 3 months after operation, which may be related to significant weight loss, ratio imbalance of bile acid to and cholesterol, intestinal microbiota, injury of vagus nerve, significant increasing in mucin of gallbladder, and without oral ursodeoxycholic acid as prescribed by the doctor. The body weight, body mass index, waistline, systolic blood pressure, and diastolic blood pressure of 5 patients with severe obesity were (100±15)
目的探讨腹腔镜胃-肠-幽门保留术(SIPS)治疗重度肥胖的临床疗效。方法采用回顾性和描述性研究。收集吉林大学附属中日联合医院2018年10月至11月收治的5例重度肥胖患者的临床资料。男1例,女4例,年龄18~55岁,平均33岁。5例患者均行腹腔镜SIPS。观察指标:(1)手术情况;(2) 术后情况;(3) 后续行动。截至2019年2月,通过门诊检查、电话访谈和微信进行随访,包括术后3个月的一般情况、体重变化、体重指数、腰围、血压、超重率、空腹血糖、糖化血红蛋白、血脂和尿酸。正态分布的测量数据用Mean±SD表示,并用Hoteling T2检验。具有偏斜分布的测量数据表示为M(范围)。结果(1)手术情况:5例患者在明确的手术范围内成功地进行了腹腔镜SIPS,无明显出血、转为开放性手术或围手术期死亡。手术时间为240分钟(范围165-345分钟)。(2) 术后情况:首次下床活动的时间、首次和胀气的时间、初次饮酒和液体摄入的时间分别为2天(范围,2-3天)、3天(范围:2-3天)和3天(时间:3-4天)。术后第3天,5例患者均经上消化道造影证实吻合口通畅,无胃漏、狭窄或梗阻。喂食后第4天取下腹部引流管,没有明显的不适,也没有从引流管中提取异物。术后住院时间为6天(范围6-7天)。(3) 随访:5例重度肥胖患者成功随访3个月。在随访期间,一名患者排便频率显著增加,大约每天5-8次,尤其是在吃油腻食物后。根据病例管理者的饮食指导,在减少油性食物的摄入后,腹泻得到了显著改善。在5例重度肥胖患者中,彩色多普勒超声检查显示,2例患者术后3个月出现胆汁淤积,这可能与体重显著减轻、胆汁酸与胆固醇比例失衡、肠道微生物群、迷走神经损伤、胆囊粘蛋白显著增加有关,并且没有医生所开的口服熊去氧胆酸。5例重度肥胖患者术后3个月的体重、体重指数、腰围、收缩压和舒张压分别为(100±15)kg、(36±4)kg/m2、(111±10)cm、(130±12)mmHg(1mmHg=0.133kPa)和(78±14)mmHg,与术前比较有显著性差异(F=61.631、75.558、87.045、9.501、16.248,P<0.05)。在5例重度肥胖患者中,2例2型糖尿病患者术后空腹血糖分别从9.55 mmol/L和13.49 mmol/L降至5.18 mmol/L和5.62 mmol/L。术后糖化血红蛋白水平分别从10.0%和9.9%下降到5.2%和6.2%。在2例高脂血症患者中,1例高甘油三酯患者的甘油三酯、总胆固醇和低密度脂蛋白水平从术前的2.24mmol/L、4.84mmol/L和2.92mmol/L升高到术后的2.47mmol/L、6.68mmol/L和5.51mmol/L,另一例高胆固醇患者术后胆固醇水平由术前的5.97mmol/L降至术后的5.75mmol/L。3例高尿酸血症患者中,2例术后尿酸由404μmol/L和484μmol/L分别降至319μmol/L和417μmol/L,1例术后尿由531μmol/L升至674μmol/L。结论腹腔镜SIPS对重度肥胖患者有显著的短期疗效,但其长期安全性和疗效有待进一步随访。关键词:肥胖;2型糖尿病;保留胃肠幽门的手术;胆胰分流手术;腹腔镜检查
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引用次数: 0
Clinical efficacy of percutaneous nephroscopy in the treatment of retroperitioneal abscess after common bile duct exploration 经皮肾镜治疗胆总管探查后腹膜后脓肿的临床疗效观察
Q4 Medicine Pub Date : 2019-12-20 DOI: 10.3760/CMA.J.ISSN.1673-9752.2019.12.012
Zhi-gang Zhang, H. Jiao, S. Zhuang, Jian Li, Hai-ming Lu, Zuoqian Wang, Jing Wang, Suxi Huang
Objective To investigate the clinical efficacy of percutaneous nephroscopy in the treatment of retroperitioneal abscess after common bile duct exploration. Methods The retrospective and descriptive study was conducted. The clinical data of 13 patients with retroperitioneal abscess after common bile duct exploration who were admitted to Xinjiang Autonomous Region Hospital of Chinese People′s Armed Forces between January 2004 and December 2018 were collected.There were 5 males and 8 females, aged from 34 to 81 years, with an average age of 57 years. All the 13 patients underwent debridement and drainage for retroperitioneal abscess under percutaneous nephroscope. Observation indicators: (1) surgical and postoperative situations; (2) follow-up. Follow-up was performed using outpatient examination and telephone interview to detect postoperative choledocholithiasis recurrence up to September 2019. Measurement data with skewed distribution were represented as M (range). Count data were described as absolute numbers. Results (1) Surgical and postoperative situations: all the 13 patients underwent successfully debridement and drainage for retroperitioneal abscess under percutaneous nephroscope, without kidney injury, pancreatic damage, vascular injury or peritoneal damage. There were 11 cases with 1 drainage tube, and 2 cases with 2 drainage tubes. The operation time, volume of intraoperative pus extracted, time to body temperature resuming to normal of 13 patients were 41 minutes (range, 24-77 minutes), 241 mL (range, 110-640 mL), 1.5 days (range, 1.0-4.0 days), respectively. The time to postoperative removal of drainage tube of 13 patients was 42 days(range, 5-94 days), in which the time to postoperative removal of drainage tube at right iliac region was 5 days and 11 days in 2 patients, and at lower back was 23-94 days in 11 patients, respectively. Duration of postoperative hospital stay was 42 days (range, 26-67 days). All the 13 patients had pleural effusion disappeared, and were cured and discharged. (2) Follow-up: 13 patients were followed up for 6-48 months, with a median time of 18 months. No recurrence occurred. Conclusion The treatment with percutaneous nephroscopy is safe and effective for retroperitioneal abscess after common bile duct exploration. Key words: Retroperitioneal abscess; Hepatolithiasis; Percutaneous nephroscope; Common bile duct exploration; Postoperative complications; Treatment
目的探讨经皮肾镜治疗胆总管探查术后腹膜后脓肿的临床疗效。方法采用回顾性和描述性研究。收集2004年1月至2018年12月在中国人民武装部队新疆自治区医院收治的13例胆总管探查术后腹膜后脓肿患者的临床资料。男5例,女8例,年龄34~81岁,平均57岁。13例患者均在经皮肾镜下对腹膜后脓肿进行清创引流。观察指标:(1)手术及术后情况;(2) 后续行动。截至2019年9月,通过门诊检查和电话访谈进行随访,以检测术后胆总管结石复发。具有偏斜分布的测量数据表示为M(范围)。计数数据被描述为绝对数。结果(1)手术及术后情况:13例患者均在经皮肾镜下成功清创引流腹膜后脓肿,无肾损伤、胰腺损伤、血管损伤或腹膜损伤。其中11例有1根引流管,2例有2根引流管。13例患者的手术时间、术中拔脓量、体温恢复正常时间分别为41分钟(24-77分钟)、241毫升(110-640毫升)、1.5天(1.0-4.0天)。13例患者术后拔除引流管的时间为42天(范围为5-94天),其中右髂区引流管的拔除时间分别为5天和11天,下背部引流管的拔出时间分别为23-94天。术后住院时间为42天(26-67天)。13例患者胸腔积液全部消失,治愈出院。(2) 随访:13例患者随访时间为6-48个月,中位随访时间为18个月。没有复发。结论经皮肾镜治疗胆总管探查术后腹膜后脓肿安全有效。关键词:腹膜后脓肿;肝结石;经皮肾镜;胆总管探查;术后并发症;治疗
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引用次数: 0
Treatment strategies of complicated extrahepatic bileduct stones 复杂肝外胆管结石的治疗策略
Q4 Medicine Pub Date : 2019-12-20 DOI: 10.3760/CMA.J.ISSN.1673-9752.2019.12.005
Wang Jian, Chen Wei
Complicated extrahepatic bile duct stone is defined as not easy to achieve the treatment standard of total stone clearance, stricture removal, unobstructed drainage and recurrence preventing in a single operation or combined with other liver diseases, which include hepatic hilar bile duct stones incarceration, distal bile duct stone incarceration, Mirizzi syndrome, residual cystic duct stones, recurrent extrahepatic bile duct stones, and combined with portal hypertension or intrahepatic bile duct stones. Through comprehensive and meticulous preoperative evaluation, we can clarify the cause of extrahepatic bile duct stones, the location of stones and bile duct stenosis, the variability of bile duct, the anatomy of the hepatoduodenal ligament, the condition of liver function and biliary tract infection, and make the proper surgery plan. During the surgery, we apply the perihilar surgical techniques, pancreatic hilar plate reduction techniques, Oddi sphincter incision and shaping, and choledochoscopic lithotripsy and lithotomy comprehensively to achieve the goal of reducing residual stone rate and recurrence rate. It is important that reasonably select endoscopic retrograde cholangiopancreatography indications, correctly hold indications of bilioenteric anastomosis, and prevent iatrogenic injury of extrahepatic bile ducts on the premise of clearing stones. Key words: Hepatolithiasis; Extrahepatic bileduct stone; Perihilar surgical techniques; Pancreatic hilar plate reduction techniques; Choledochoscope; Lithotripsy
复杂性肝外胆管结石是指单次手术或与其他肝病联合治疗不易达到结石清除率、狭窄清除率、引流通畅率和预防复发率的治疗标准,包括肝门部胆管结石嵌顿、远端胆管结石嵌闭、Mirizzi综合征、残余胆囊管结石、,复发性肝外胆管结石,并合并门静脉高压或肝内胆管结石。通过全面细致的术前评估,我们可以明确肝外胆管结石的病因、结石和胆管狭窄的位置、胆管的变异性、肝十二指肠韧带的解剖结构、肝功能和胆道感染的情况,并制定适当的手术计划。在手术中,我们综合运用肝门周围手术技术、胰门钢板复位技术、Oddi括约肌切开整形、胆道镜碎石术和取石术,以达到降低残余结石率和复发率的目的。合理选择内镜逆行胰胆管造影指征,正确把握胆肠吻合术指征,在清除结石的前提下,预防医源性肝外胆管损伤,具有重要意义。关键词:肝结石;肝外胆管结石;肝门周围手术技术;胰门钢板复位术;胆道镜;碎石
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引用次数: 0
Minutes of the third conference of the third editorial board of Chinese journal of digestive surgery 中国消化外科杂志第三届编委会第三次会议纪要
Q4 Medicine Pub Date : 2019-12-20 DOI: 10.3760/CMA.J.ISSN.1673-9752.2019.12.102
Linlin Shen, Liang Xia, Yulin Zhang, J. Huo, P. Jiang, Yingfen Zou, D. Tao
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引用次数: 0
Effects of definitive repair surgery on health-related quality of life in patients with bile duct injury after laparoscopic cholecystectomy 确定修复手术对腹腔镜胆囊切除术后胆管损伤患者健康相关生活质量的影响
Q4 Medicine Pub Date : 2019-12-20 DOI: 10.3760/CMA.J.ISSN.1673-9752.2019.12.010
Xintao Zeng, Pei-min Yang, Hua-xin Luo, Wei Zhang, Sirui Chen, Junyang Peng, Wentao Wang
Objective To investigate the effects of definitive repair surgery on health-related quality of life (HRQOL) in patients with bile duct injury after laparoscopic cholecystectomy (LC). Methods The retrospective case-control study was conducted. The clinicopathological data of 181 patients with bile duct injury caused by LC for benign gallbladder diseases who underwent definitive repair surgery and 50 patients without complications after LC for benign gallbladder diseases in the Mianyang Central Hospital from January 2000 to December 2017 were collected. There were 82 males and 99 females of 181 patients with bile duct injury, aged from 31 to 68 years, with an average age of 47 years. Definitive repair surgery was performed according to different types of bile duct injury, and questionnaire of HRQOL was conducted preoperatively and one year after operation. There were 18 males and 32 females of 50 patients without complications after LC, aged from 35 to 69 years, with an average age of 41 years. Questionnaire of HRQOL was conducted on LC patients without complications one year after operation. Observation indicators: (1) classification of bile duct injury; (2) intraoperative situations of definitive repair surgery; (3) postoperative situations of definitive repair surgery; (4) follow-up; (5) results of the SF-36 scale assessment. Follow-up was conducted by outpatient examination and telephone interview up to December 2018. Patients were reexamined liver function and color Doppler ultrasonography once every 6-12 months, and further magnetic resonance cholangiopancreatography (MRCP) or computed tomography examination to detect recurrence of anastomotic biliary stricture and cholangitis. Measurement data with normal distribution were expressed as Mean±SD, and comparison between groups was analyzed by the paired t test. Measurement data with skewed distribution were described as M (range), and count data were described as absolute numbers. Results (1) Classification of bile duct injury: of the 181 patients with bile duct injury, there were 64 cases of E1 type, 70 cases of E2 type, 35 cases of E3 type, 9 cases of E4 type, and 3 cases of E5 type. (2) Intraoperative situations of definitive repair surgery: all the 181 patinets with bile duct injury underwent definitive repair surgery successfully, including 61 undergoing end-to-end biliary anastomosis, 109 undergoing Roux-en-Y choledojejunostomy, 11 undergoing hemi-hepatectomy combined with Roux-en-Y anastomosis. There were 52 patients combined with hilar cholangioplasty. The operation time and volume of intraoperative blood loss of 181 patients were (190±126) minutes and 601.5 mL (range, 150.0-2 100.0 mL). There were 24 cases with blood transfusion and 18 cases with T-tube stent. (3) Postoperative situations of definitive repair surgery: 40 of 181 patients had complications, including 14 cases of incisional infection, 10 cases of bile leakage, 8 cases of perihepatic effusion, 7 cases of pulmo
目的探讨腹腔镜胆囊切除术(LC)后胆管损伤患者行确定性修复手术对健康相关生活质量(HRQOL)的影响。方法采用回顾性病例对照研究。收集2000年1月至2017年12月绵阳市中心医院181例胆囊良性疾病LC所致胆管损伤患者和50例胆囊良性病变LC术后无并发症患者的临床病理资料。181例胆管损伤患者中,男性82例,女性99例,年龄31~68岁,平均47岁。根据不同类型的胆管损伤进行明确的修复手术,并在术前和术后一年进行HRQOL问卷调查。50例LC术后无并发症的患者中,男18例,女32例,年龄35-69岁,平均41岁。对术后1年无并发症的LC患者进行HRQOL问卷调查。观察指标:(1)胆管损伤的分类;(2) 确定性修复手术的术中情况;(3) 确定性修复手术的术后情况;(4) 后续行动;(5) SF-36量表评估结果。截至2018年12月,通过门诊检查和电话访谈进行了随访。患者每6-12个月复查一次肝功能和彩色多普勒超声,并进一步进行磁共振胰胆管成像(MRCP)或计算机断层扫描检查,以检测吻合口胆管狭窄和胆管炎的复发。具有正态分布的测量数据表示为Mean±SD,并通过配对t检验分析各组之间的比较。具有偏斜分布的测量数据描述为M(范围),计数数据描述为绝对数。结果(1)胆管损伤的分类:181例胆管损伤患者中,E1型64例,E2型70例,E3型35例,E4型9例,E5型3例。(2) 确定性修复手术的术中情况:181例胆管损伤患者均成功进行了确定性修复手术,其中61例行端对端胆道吻合,109例行Roux-en-Y胆总管吻合术,11例行半肝切除联合Roux-en-Y吻合。合并肝门部胆管成形术52例。181例患者的手术时间和术中失血量分别为(190±126)分钟和601.5 mL(范围150.0-2 100.0 mL)。其中输血24例,T型管支架18例。(3) 确定性修复手术的术后情况:181例患者中有40例出现并发症,其中切口感染14例,胆汁渗漏10例,肝周积液8例,肺部感染7例,腹部出血1例。术后腹部出血患者再次手术止血,其他并发症患者经超声引导穿刺引流或保守治疗后治愈。181例胆管损伤患者术后住院时间为12.6天(6.0-34.0天)。没有发生围手术期死亡。(4) 随访:181例患者中有157例随访8.2-201.3个月,中位随访时间为92.7个月。28例吻合口狭窄复发,其中16例再次手术治疗,10例内镜下支架置入术治疗,2例介入科球囊扩张术治疗;所有病例均再次修复狭窄。13例患者为复发性胆管炎,MRCP显示吻合口无明显狭窄,保守治疗后症状可得到有效控制。(5) SF-36量表评估结果:181名胆管损伤患者在最终修复手术前完成了SF-36评分,157名患者在最终修补手术后一年完成。所有50例无并发症的患者在LC术后1年完成了SF-36量表。181例胆管损伤患者术前HRQOL在生理功能、角色功能、躯体疼痛、总体健康、活力、社会功能、情绪功能、心理健康、身体成分汇总和心理成分汇总方面的得分分别为79±15、65±12、40±17,分别为42±14、59±20、27±15、48±23、56±22、60±11和56±11。确定性修复术后一年的上述指标分别为87±10、78±15、71±20、64±20、68±19、70±25、67±21、69±23、71±13、68±15。50例LC术后1年无并发症患者的上述指标分别为90±13、81±20、87±16、72±20、73±15、86±17、79±22、77±19、82±18、79±18。 181例胆管损伤患者在明确修复术后1年以上各项指标均有显著提高(t=2.051、2.016、3.875、3.014、2.563、3.225、2.964、2.357、2.150、2.203,P 0.05);胆管狭窄;胆管炎;胆囊切除术;与健康相关的生活质量;确定性修复手术;腹腔镜检查
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引用次数: 0
Diagnosis and treatment of small bowel volvulus comorbid with abdominal chylous ascites 小肠扭转合并腹腔乳糜腹水的诊断与治疗
Q4 Medicine Pub Date : 2019-12-20 DOI: 10.3760/CMA.J.ISSN.1673-9752.2019.12.016
Yan Xu, Xiaoling Hu, R. Dong, Jiangbin Li, Chen Yafeng, Nianan Luo, Li He
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引用次数: 0
Application value of MRI examination in classification diagnosis of rectal mucinous adenocarcinoma MRI检查在直肠粘液腺癌分类诊断中的应用价值
Q4 Medicine Pub Date : 2019-12-20 DOI: 10.3760/CMA.J.ISSN.1673-9752.2019.12.015
Jun-da Wang, Yanyang Li, Yu Fang, He Ren, Ying-jiang Liu, Huiping Yang, Xiu-ting Mei, Hua Yang
Objective To investigate the application value of magnetic resonance imaging (MRI) in the classification diagnosis of rectal mucinous adenocarcinoma. Methods The retrospective and descriptive study was conducted. The clinical data of 74 patients with rectal mucinous adenocarcinoma who were admitted to Chongqing Traditional Chinese Medicine Hospital from July 2009 and February 2019 were collected. There were 40 males and 34 females, aged (46±8)years, with a range from 32 to 82 years. Among the 74 patients, 41 were simple mucinous adenocarcinoma, 26 were partial mucinous adenocarcinoma, and 7 were focal or small foci mucinous adenocarcinoma. All patients underwent MRI plain scan and dynamic enhanced scan. Observation indicators: (1) morphology of rectal mucinous adenocarcinoma; (2) the lesion margin of rectal mucinous adenocarcinoma; (3) the value of apparent diffusion coefficient (ADC) of rectal mucinous adenocarcinoma; (4) internal enhancement features of rectal mucinous adenocarcinoma; (5) timesignal intensity curve of rectal mucinous adenocarcinoma. Measurement data with normal distribution were represented as Mean±SD, and count data were described as absolute numbers. Results (1) Morphology of rectal mucinous adenocarcinoma: 74 patients had different morphological changes. Among the 41 cases of simple mucinous adenocarcinoma, 22 were oval, 8 were round, and 11 were irregular. Among the 26 patients with partial mucinous adenocarcinoma, 15 were oval, 8 were round and 3 were irregular. Among the 7 patients with focal or small foci mucinous adenocarcinoma, 2 were oval, 1 was round and 4 were irregular. (2) The lesion margin of rectal mucinous adenocarcinoma: the lesion margin of 74 patients was mainly unclear and irregular. Among the 41 cases of simple mucinous adenocarcinoma, 32 had unclear and irregular margin, 7 had clear margin, and 2 had unclear margin combined with fissure. Among the 26 cases of partial mucinous adenocarcinoma, 20 had unclear margin combined with fissure, 5 had unclear margin and irregular margin, and 1 had clear margin. Among the 7 patients with focal or small foci mucinous adenocarcinoma, 5 had unclear or irregular margin, 1 had unclear or irregular margin, and 1 had clear margin. (3) The value of ADC of rectal mucinous adenocarcinoma: diffusion weighted imaging of 74 patients showed diffused limited changes. The average ADC value was (1.24±0.23)×10-3 mm2/s of 41 patients with simple mucinous adenocarcinoma, (0.91±0.42)×10-3 mm2/s of 26 patients with partial mucinous adenocarcinoma, and (1.07±0.24)×10-3 mm2/s of 7 patients with focal or small mucinous adenocarcinoma. (4) Internal enhancement features of rectal mucinous adenocarcinoma: 74 patients showed delayed heterogeneous enhancement and marginal enhancement. Among 41 cases of simple mucinous adenocarcinoma, 24 showed delayed heterogeneous enhancement, 17 showed marginal enhancement, and none showed homogeneous enhancement. Among 26 patients with partial mu
目的探讨磁共振成像(MRI)在直肠粘液腺癌分类诊断中的应用价值。方法采用回顾性和描述性研究。收集2009年7月至2019年2月重庆中医院收治的74例直肠粘液腺癌患者的临床资料。男性40例,女性34例,年龄(46±8)岁,年龄32 ~ 82岁。74例患者中,单纯性粘液腺癌41例,部分性粘液腺癌26例,局灶性或小灶性粘液腺癌7例。所有患者均行MRI平扫和动态增强扫描。观察指标:(1)直肠粘液腺癌形态学;(2)直肠粘液腺癌病变边缘;(3)直肠粘液腺癌的表观扩散系数(ADC)值;(4)直肠粘液腺癌的内部增强特征;(5)直肠粘液腺癌的时间信号强度曲线。计量资料为正态分布,用Mean±SD表示,计数资料用绝数表示。结果(1)直肠粘液腺癌形态学:74例患者有不同的形态学改变。41例单纯性粘液腺癌中,卵圆形22例,圆形8例,不规则11例。26例部分黏液腺癌中,卵圆形15例,圆形8例,不规则3例。7例局灶性或小灶性黏液腺癌,2例卵圆形,1例圆形,4例不规则。(2)直肠粘液腺癌病变边缘:74例患者病变边缘以不清晰、不规则为主。41例单纯性粘液腺癌中,32例边界不清不规则,7例边界清晰,2例边界不清合并裂隙。26例部分黏液腺癌中,边缘不清伴裂20例,边缘不清伴不规则5例,边缘清晰1例。7例局灶性或小灶性黏液腺癌中,5例边缘不清或不规则,1例边缘不清或不规则,1例边缘清晰。(3)直肠粘液腺癌ADC的价值:74例患者弥散加权成像显示弥漫性有限改变。41例单纯性粘液腺癌的平均ADC值为(1.24±0.23)×10-3 mm2/s, 26例部分性粘液腺癌的平均ADC值为(0.91±0.42)×10-3 mm2/s, 7例局灶性或小型粘液腺癌的平均ADC值为(1.07±0.24)×10-3 mm2/s。(4)直肠粘液腺癌的内部强化特征:74例患者表现为迟发性非均匀强化和边缘强化。41例单纯性粘液腺癌中,迟发性非均匀强化24例,边缘性强化17例,均质强化无一例。在26例部分粘液腺癌患者中,20例为边缘强化,6例为均匀强化,无一例为非均匀强化。7例局灶性或小局灶性粘液腺癌均表现不均匀强化。(5)直肠粘液腺癌时间信号强度曲线:74例患者时间信号强度曲线以流出型为主。41例单纯性粘液腺癌中22例为进行性曲线型,12例为平台型,7例为流出型。26例部分粘液腺癌中,流出型17例,平台型8例,进行性1例。7例局灶性小力黏液腺癌中,流出型4例,平台型2例,进行性1例。结论不同类型直肠粘液腺癌的MRI表现不同。正确认识不同类型直肠粘液腺癌的MRI表现,有助于直肠粘液腺癌的分类诊断。关键词:直肠肿瘤;直肠粘液腺癌;粘液湖;磁共振成像
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引用次数: 0
Application value of ultrasound interventional technique in the treatment of severe acute pancreatitis 超声介入技术在重症急性胰腺炎治疗中的应用价值
Q4 Medicine Pub Date : 2019-12-20 DOI: 10.3760/CMA.J.ISSN.1673-9752.2019.12.017
Jia Tang
Severe acute pancreatitis (SAP) is an acute abdominal disease characterized by acute onset, serious illness, multiple complications, and high mortality. Surgical interventions have been used throughout the treatment of SAP for a long time, including traditional surgical treatments led by laparotomy and modern surgical treatments led by minimally invasive surgery. Especially in the past 10 years, with the deep understanding of the etiology and pathology of SAP and the increasing complications of traditional surgical treatments, a series of minimally invasive surgical techniques are widely applied in the clinical treatment of SAP, which achieved satisfactory clinical results. Among them, ultrasonic intervention technology plays a key role in the advantages of convenience, minimal invasiveness and strong repeatability. Based on recent literatures at home and abroad, this article reviews the application value of ultrasound interventional techniques in the treatment of SAP. Key words: Minimally invasive surgery; Severe acute pancreatitis; Ultrasonic intervention; Tube drainage; Treatment
严重急性胰腺炎(SAP)是一种急性腹部疾病,其特点是起病急、病情严重、并发症多、死亡率高。长期以来,手术干预一直贯穿于SAP的整个治疗过程,包括以开腹手术为主的传统手术治疗和以微创手术为主的现代手术治疗。特别是近10年来,随着对SAP病因病理认识的深入和传统手术治疗并发症的增多,一系列微创手术技术被广泛应用于SAP的临床治疗,取得了满意的临床效果。其中,超声介入技术以其方便、微创、重复性强等优势发挥着关键作用。本文结合国内外最新文献,综述超声介入技术在SAP治疗中的应用价值。关键词:微创手术;严重急性胰腺炎;超声介入;管引流;治疗
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引用次数: 0
Clinical efficacy of laparoscopic splenectomy combined with pericardial devascularization in the treatment of cirrhotic portal hypertension: a report of 425 cases 腹腔镜脾切除术联合心包断流术治疗肝硬化门静脉高压症425例临床疗效分析
Q4 Medicine Pub Date : 2019-12-20 DOI: 10.3760/CMA.J.ISSN.1673-9752.2019.12.009
Jiang Guo-qing, Bai Dousheng, Qian Jianjun, Jin Shengjie, Z. Chi, W. Qian, Zhou Baohuan, Wang Aoqing
Objective To investigate the clinical efficacy of laparoscopic splenectomy combined with pericardial devascularization in the treatment of cirrhotic patients with cirrhotic portal hypertension. Methods The retrospective and descriptive study was conducted. The clinicopathological data of 425 patients with cirrhotic portal hypertension who were admitted to Northern Jiangsu People′s Hospital Affiliated to Yangzhou University were collected. There were 289 males and 136 females, aged (53±11)years, with a range from 21 to 79 years. All the patients were allocated into 3 periods according to the operation time, including 100 patients of early period from February 2012 to March 2014, 156 patients of mature technology period from April 2014 to August 2016, and 169 patients of technology innovation period from september 2016 to December 2018. The patients of early period and mature technology period underwent laparoscopic splenectomy combined with pericardial devascularization, and the patients of technology innovation period underwent vagus nerve-preserving laparoscopic splenectomy combined with pericardial devascularization. Observation indicators: (1) surgical situations; (2) postoperative situations; (3) follow-up. Patients were followed up by outpatient examination to detect the upper digestive rebleeding, gastric retention, and diarrhea up to March 2019. Sequential therapy of endoscopic variceal ligation (EVL) was slectively performed on patients based on results of gastroscopy. Measurement data with normal distribution were represented as Mean±SD, and comparison between groups was analyzed using ANOVA, and paired comparison was analyzed using the t test. Measurement data with skewed distribution were represented as M (range), and comparison between groups was anlyzed using the Kruskal-Wallis rank sum test, and paired comparison was analyzed using the rank sum test. Count data were described as absolute numbers or percentages, and comparison between groups was analyzed using the chi-square test and Fisher exact probability. Results (1) Surgical situations: the operation time, volume of intraoperative blood loss, cases with intraoperative blood transfusion, cases with conversion to open surgery, and cases with emergency operation for bleeding were (187±46)minutes, 150 mL (range, 50-1 300 mL), 2, 2 , 1 for patients of early period, (164±22)minutes, 50 mL (range, 30-100 mL), 1, 1, 1 for patients of mature technology period, and (150±18)minutes, 50 mL (range, 10-300 mL), 0 , 0 , 0 for patients of technology innovation period, respectively. There were significant differences in the operation time and volume of intraoperative blood loss between the three groups (F=55.482, χ2=94.620, P 0.05). (2) Postoperative situations: 425 patients had oral aspirin enteric-coated tablets for prevention of thrombus, with no perioperative death. Duration of postoperative hospital stay, cases with portal vein thrombosis at postoperative 7 days, cases with pan
目的探讨腹腔镜脾切除术联合心包断流术治疗肝硬化门静脉高压症的临床疗效。方法采用回顾性和描述性研究。收集扬州大学附属苏北人民医院收治的425例肝硬化门静脉高压症患者的临床病理资料。男性289例,女性136例,年龄(53±11)岁,年龄21 ~ 79岁。所有患者根据手术时间分为3期,其中前期100例(2012年2月- 2014年3月),技术成熟期156例(2014年4月- 2016年8月),技术创新期169例(2016年9月- 2018年12月)。技术早期和成熟期患者行腹腔镜脾切除术联合心包断流术,技术创新期患者行保留迷走神经的腹腔镜脾切除术联合心包断流术。观察指标:(1)手术情况;(2)术后情况;(3)跟进。随访至2019年3月,门诊检查患者是否出现上消化道再出血、胃潴留和腹泻。根据胃镜检查结果选择性地对患者进行内镜下静脉曲张结扎(EVL)序贯治疗。计量资料呈正态分布用Mean±SD表示,组间比较采用方差分析,配对比较采用t检验。偏态分布的计量资料用M(极差)表示,组间比较采用Kruskal-Wallis秩和检验,配对比较采用秩和检验。计数数据以绝对数字或百分比描述,组间比较采用卡方检验和Fisher精确概率进行分析。(1)手术情况:手术时间、术中失血,例术中输血、例开放手术,并例紧急手术出血(187±46)分钟,150毫升(范围、博彩300毫升),2,2,1对病人的早期,(164±22)分钟,50毫升(范围、30 - 100毫升),1,1,1对病人的成熟的技术,(150±18)分钟,50毫升(范围、10 - 300毫升),0,0,0技术创新时期的患者,分别。三组手术时间、术中出血量比较,差异均有统计学意义(F=55.482, χ2=94.620, p0.05)。(2)术后情况:425例患者口服阿司匹林肠溶片预防血栓形成,无围手术期死亡病例。术后住院时间、术后7天门静脉血栓、胰瘘、肺部感染、腹部感染分别为:早期患者(11.0±2.9)天、46、2、1、0天,技术成熟期患者(9.9±1.7)天、81、3、0天,技术创新期患者(8.8±1.3)天、83、2、1、1天。三组患者术后住院时间比较差异有统计学意义(F=39.836, P 0.05),胰瘘、肺部感染、腹部感染三组患者比较差异无统计学意义(P < 0.05)。术后7天门静脉血栓患者口服阿司匹林肠溶片或华法林治疗。胰瘘、肺部感染、腹部感染患者经保守治疗均治愈出院。(3)随访:425例患者均随访1 ~ 72个月,中位随访36个月。425例患者中,术后序贯EVL治疗261例,其中技术成熟期133例,技术创新期128例。261例术后接受EVL顺序治疗的患者上消化道再出血发生率为3.83%(10/261),164例未接受EVL顺序治疗的患者上消化道再出血发生率为17.68%(29/164),差异有统计学意义(χ2=23.185, P<0.05)。133例EVL序贯治疗患者在技术成熟期胃潴留和腹泻的发生率分别为96.24%(128/133)和61.65%(82/133),128例EVL序贯治疗患者在技术创新期胃潴留和腹泻的发生率分别为1.56%(2/128)和3.91%(5/128),差异有统计学意义(χ2=233.876、97.883,P<0.05)。 结论腹腔镜脾切除术联合心包断流术治疗肝硬化门静脉高压症是安全可行的,术中保留迷走神经可减少术中出血量和术后并发症的发生。关键词:肝硬化;门静脉高压;脾切除术;心包devascularization;迷走神经;腹腔镜检查
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中华消化外科杂志
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