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Sarcomatoid carcinoma of colon: Report of a rare case 结肠癌肉瘤样癌1例报告
Pub Date : 2023-08-15 DOI: 10.18231/j.jdpo.2023.040
Asreen Suhana, J. Sharma, B. Bharadwaj, A. P. Beso, Muktanjalee Deka, Upasana Kalita, B. Goswami
Sarcomatoid carcinoma of colon is an extremely rare biphasic tumour with less than 50 reported cases in literature, either as Sarcomatoid carcinoma or carcinosarcoma. Here, we report a case of a 65 years old lady who presented with pain abdomen. On colonoscopy, a colonic mass was noted with intussusception. Right hemicolectomy was performed and the specimen was sent for histopathological examination. Following histopathology and immunohistochemistry, it was reported as Sarcomatoid carcinoma of Colon.
结肠肉瘤样癌是一种极为罕见的双相肿瘤,文献报道病例不足50例,可表现为肉瘤样癌或癌肉瘤。在这里,我们报告一个65岁的妇女谁提出腹痛。结肠镜检查发现结肠肿块伴肠套叠。行右半结肠切除术,标本送组织病理检查。经组织病理学和免疫组化检查,报告为结肠癌肉瘤样癌。
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引用次数: 0
Catscratch disease in an SLE patient -A case report 狼疮患者猫抓病1例报告
Pub Date : 2023-08-15 DOI: 10.18231/j.jdpo.2023.042
L. K, R. Abraham
Catscratch disease[CSD] is a self limited lymphadenitis caused by Bartonella Henselae and transmitted by cats. This typically affects children and young adults. Immunosuppression is considered as a risk factor for severe and atypical forms of the disease. We are reporting such a case of Catscratch disease in a patient with Systemic Lupus Erythematosus while receiving immunosupressant therapy.
猫抓病[CSD]是由亨塞拉巴尔通体引起的一种由猫传播的自限性淋巴结炎。这通常影响儿童和年轻人。免疫抑制被认为是严重和非典型形式的疾病的危险因素。我们报告这样一个病例Catscratch病的病人与系统性红斑狼疮而接受免疫抑制剂治疗。
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引用次数: 0
Clinicopathological profile of triple negative breast cancer in a tertiary health care centre of India 印度三级保健中心三阴性乳腺癌的临床病理分析
Pub Date : 2023-08-15 DOI: 10.18231/j.jdpo.2023.032
Saqib Ahmed, G. Patel, Ruhi Hasan, Mahboob Hasan
Breast carcinoma is one of the most common malignancies affecting women in developing countries. It is divided into several subtypes, including triple negatives. TNBCs are found to have an aggressive behaviour and have a metastasic potential leading to an overall poorer prognosis.The aim was to study the clinicopathological profile of TNBC pateints including parameters like age, site, tumour size, histopathological type, histologic grade, lymphovascular invasion and nodal invasion and TNM Staging was done to study the overall prognosis.A four year retrospective study was conducted on ninety seven cases of breast carcinoma which were further classified based on immunohistochemical staining into four subtypes. The clinicopathological details and the histomorphological features of these patents were studied.Of the 208 cases, 97 cases were diagnosed as TNBC. The average age at presentation was 45 years. Most of the cases showed Nottingham Modification of Scarff Bloom-Richardson (NMBR) grade 3 (66%) and stage II (50.7%). Lymph node metastasis and Lymphovascular invasion was seen in 62% and 24.7% of cases. Infiltrating ductal carcinoma (not otherwise specified) type (94.8%) was the most common histological type. TNBC have an aggressive behaviour compared to other subtypes with higher SBR grade. Lymphovascular invasion and nodal metastasis.
乳腺癌是影响发展中国家妇女的最常见的恶性肿瘤之一。它分为几个亚型,包括三重阴性。发现tnbc具有侵袭性行为和转移潜力,导致整体预后较差。目的是研究TNBC患者的临床病理特征,包括年龄、部位、肿瘤大小、组织病理类型、组织学分级、淋巴血管侵袭及淋巴结侵袭等参数,并进行TNM分期,研究整体预后。对97例乳腺癌进行了为期4年的回顾性研究,并根据免疫组化染色将其分为4个亚型。我们对这些病例的临床病理细节和组织形态学特征进行了研究。在208例中,97例被诊断为TNBC。发病时的平均年龄为45岁。大多数病例表现为Nottingham Modification of Scarff Bloom-Richardson (NMBR) 3级(66%)和II期(50.7%)。淋巴结转移和淋巴血管侵犯分别占62%和24.7%。浸润性导管癌(未另行说明)类型(94.8%)是最常见的组织学类型。与其他SBR分级较高的亚型相比,TNBC具有攻击行为。淋巴血管侵袭及淋巴结转移。
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引用次数: 0
T-cell transfer therapy: A primer t细胞转移治疗:引物
Pub Date : 2023-08-15 DOI: 10.18231/j.jdpo.2023.030
I. Chakrabarti
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引用次数: 0
Subcutaneous basidiobolomycosis: An unusual fungus in immuno-competent children, vindicating longer duration of anti-fungal treatment 皮下担子球菌病:一种罕见的真菌在免疫能力的儿童,证明抗真菌治疗的持续时间较长
Pub Date : 2023-08-15 DOI: 10.18231/j.jdpo.2023.041
Kiruthiga K.G, Prachi Sharma, Aparna M. Joshi, A. Pradhan, M. Otiv
Subcutaneous Basidiobolomycosis is a rare fungal infection caused by environmental saprophyte Basidiobolus ranarum. The disease is seen among immunocompetent individuals of age 18 months to 80 years, being more common in children. We report a case of Subcutaneous Basidiobolomycosis in a 10-year-old immunocompetent male child from Ahmednagar, Maharashtra who presented with complaints of right gluteal non tender, diffuse swelling, which was gradually progressive involving inner and back of thigh. The overlying skin was hyperpigmented with scaling at places. It was associated with complaints of difficulty in walking and voiding of urine. Patient was prescribed multiple medicines with no records available. All primary investigations were done along with a deep incisional biopsy for histopathology. MRI was suggestive of? lymphangioma? vascular malformation. Histopathology revealed panniculitis with dense collections of eosinophils. Few broad, aseptate fungal hyphae were seen camouflaged within the inflammatory infiltrate, surrounded by Splendore-Hoeppli phenomenon. The patient was treated with oral fluconazole for a period of one year with complete resolution of the symptoms. After one year of follow-up, the patient is clinically well. Clinically, this lesion presented as induration of skin and subcutaneous tissue thus mimicking a soft tissue sarcoma. However, histopathological examination clinched the diagnosis. Fungal infections are common in immuno-suppressed patients, and extremely uncommon in children. Since this is an exceptional rare fungal infection seen in immuno-competent children and young adults, it is often disregarded as a differential diagnosis.
摘要皮下担子孢子菌病是一种由环境腐生植物担子孢子引起的罕见真菌感染。该病见于18个月至80岁的免疫功能正常的个体,在儿童中更为常见。我们报告一例来自马哈拉施特拉邦艾哈迈德纳格尔的10岁免疫功能男性儿童的皮下担子球菌病,其主诉为右臀肌无触痛,弥漫性肿胀,逐渐累及大腿内侧和背部。复盖皮肤色素沉着,局部有鳞屑。它与行走困难和排尿有关。给患者开了多种药物,但没有记录。所有的初步调查都是与组织病理学的深切口活检一起完成的。MRI提示?淋巴管瘤吗?血管畸形。组织病理学显示泛膜炎伴密集的嗜酸性粒细胞聚集。少量宽的、无菌的真菌菌丝隐藏在炎性浸润中,被splendohoeppli现象所包围。患者口服氟康唑治疗一年,症状完全缓解。经过一年的随访,患者临床表现良好。临床表现为皮肤和皮下组织硬化,类似软组织肉瘤。然而,组织病理学检查确定了诊断。真菌感染在免疫抑制患者中很常见,在儿童中极为罕见。由于这是一种罕见的真菌感染,可见于免疫能力的儿童和年轻人,它往往被忽视作为鉴别诊断。
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引用次数: 0
Prevalence of odontogenic tumors: A retrospective study of an institute of Rajasthan 牙源性肿瘤的患病率:拉贾斯坦邦一家研究所的回顾性研究
Pub Date : 2023-08-15 DOI: 10.18231/j.jdpo.2023.033
Madhvi Sanwelka, Garima Mehra, M. Mehra
Odontogenic tumors are a heterogeneous group of lesions with variable clinical and pathohistological features. The purpose of this study was to investigate the epidemiological behavior of this heterogeneous group of tumors across a 2 year period and to compare these data with those in the literature. A retrospective study was made of cases of odontogenic tumors recorded at our institution between January 2021 to December 2022. The variables gender, age, anatomical site, histological type and symptoms were analyzed in 30 histopathology reports. Out of 30 cases, males show predominant cases 60% (18/30 cases) and females show 40% cases (12/30 cases). Male: female ratio is 1.5:1. According to age, the most involved age group was found to be of 11-20 years which showed highest number of cases (36.7%). Out of 30 cases, most frequent odontogenic tumor was found to be ameloblastoma (46.7%). There is a slight predominance of odontogenic tumors in men and during the first decades of life; most of them occur in the mandible. There were statistically significant differences among the variables histological type and symptoms.
牙源性肿瘤是一组异质性病变,具有不同的临床和病理组织学特征。本研究的目的是调查这一异质性肿瘤组在2年内的流行病学行为,并将这些数据与文献中的数据进行比较。回顾性研究我院2021年1月至2022年12月间记录的牙源性肿瘤病例。对30例组织病理学报告的性别、年龄、解剖部位、组织学类型和症状进行分析。在30例病例中,男性占60%(18/30例),女性占40%(12/30例)。男女比例为1.5:1。按年龄分,发病率最高的年龄组为11 ~ 20岁,占36.7%。在30例牙源性肿瘤中,以成釉细胞瘤最为常见(46.7%)。在男性和生命的头几十年里,牙源性肿瘤有轻微的优势;大多数发生在下颌骨。病理类型、症状等变量间差异有统计学意义。
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引用次数: 0
Angiomatous meningioma: A rare case report 血管瘤性脑膜瘤:1例罕见报告
Pub Date : 2023-08-15 DOI: 10.18231/j.jdpo.2023.038
A. Gupta, Palka Gouria, J. Suri
Angiomatous meningioma is a rare subtype of meningioma that accounts for 2.1-2.59% of all meningiomas. Microscopically, it shows numerous vascular spaces in addition to the normal meningothelial elements. Here, we are presenting a case of 41 years old female who presented with history of bilateral loss of vision, headache, loss of consciousness, seizures, giddiness and vomiting and was diagnosed as angiomatous meningioma on histopathological examination. Despite the availability of neuroimaging diagnostic modalities, histological examination and immunohistochemistry remain the gold standard for final diagnosis.
血管瘤性脑膜瘤是一种罕见的脑膜瘤亚型,占所有脑膜瘤的2.1-2.59%。显微镜下,除了正常的脑膜上皮外,还可见大量的血管间隙。在此,我们报告一位41岁女性病患,以双侧视力丧失、头痛、意识丧失、癫痫发作、头晕及呕吐病史,经组织病理学检查诊断为血管瘤性脑膜瘤。尽管神经影像学诊断方式的可用性,组织学检查和免疫组织化学仍然是最终诊断的金标准。
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引用次数: 0
A rare and challenging case of pineal gland tumor – A case report 罕见且具挑战性的松果体肿瘤1例
Pub Date : 2023-08-15 DOI: 10.18231/j.jdpo.2023.043
I. Bd, S. S, R. R
Pineal gland tumors are of rare occurrence and may arise from pineal parenchymal cells, the neighboring glia or residual stem cells. Due to its rarity pineal gland tumors are often misdiagnosed. The World Health Organsation (WHO) classifies and grades pineal parenchymal tumors from grade I to grade IV. We present a case report of a rare pineal parenchymal tumor (PPT) in an adult female which was diagnosed mainly on histopathology and aided by immunohistochemistry. The case report includes review of histopathological features and grading of pineal region tumors of intermediate malignancy which is necessary for further management of such cases.
松果体肿瘤是一种罕见的肿瘤,可能起源于松果体实质细胞、邻近的胶质细胞或残留的干细胞。由于其罕见,松果体肿瘤常被误诊。世界卫生组织(WHO)将松果体实质肿瘤分为I级至IV级。我们报告一例罕见的成年女性松果体实质肿瘤(PPT),主要通过组织病理学和免疫组织化学辅助诊断。病例报告包括回顾组织病理特征和分级的松果体区肿瘤的中度恶性,这是必要的进一步处理这类病例。
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引用次数: 0
Spectrum of Pap smear cytology according to The Bethesda System 2014 根据2014年Bethesda系统的巴氏涂片细胞学谱
Pub Date : 2023-08-15 DOI: 10.18231/j.jdpo.2023.034
Kamna Gupta, Preety Garg, A. Mohan, Rajnish Kumar, A. Varshney
Carcinoma of cervix is one of the leading cause of mortality in women across the world. Papanicolaou smear is a valuable screening tool for the neoplastic lesions of cervix. Present study was carried out to do clinicocytological correlation of cervical lesions and to find out the spectrum of cervical lesions in study population. An observational study was conducted at Pathology department in Muzaffarnagar Medical College, Muzaffarnagar. Total 1,017 females were enrolled, scrape smears from the cervix were taken and processed using Papanicolaou's method of staining. These stained smears were examined under microscope and classified according to latest The Bethesda System 2014. Out of 1017 cases, 84.9% (863) smears were classified satisfactory according to 2014 The Bethesda System. Majority of cases (350 cases, 40.5%) belonged to age group of 31-40 years. NILM was the most common cytological finding seen in 340 females (39.3%). The epithelial abnormalities including Atypical Squamous Cells (ASCUS, ASC-H), Squamous Intraepithelial Lesion (LSIL, HSIL) and Squamous Cell Carcinoma were seen in 3.2% of total cases. LSIL found in 1.3% cases and HSIL formed 1.0%. Single case of SCC was detected. Cervical epithelial abnormalities are common in Indian females. Pap smear is the most convenient and OPD test to detect epithelial abnormalities in early phase. Awareness regarding the Pap screening should be encouraged to lessen the morbidity and mortality caused by Carcinoma Cervix.
宫颈癌是全世界妇女死亡的主要原因之一。巴氏涂片是一种有价值的筛查宫颈肿瘤病变的工具。本研究旨在对宫颈病变进行临床细胞学相关性分析,了解研究人群宫颈病变谱。在Muzaffarnagar医学院病理学系进行了一项观察性研究。共纳入1,017名女性,取宫颈刮片,采用Papanicolaou染色法处理。这些染色的涂片在显微镜下检查,并根据最新的Bethesda系统2014进行分类。在1017例病例中,84.9%(863例)的涂片根据2014年Bethesda系统分类为满意。31 ~ 40岁年龄组占多数(350例,40.5%)。在340名女性中,NILM是最常见的细胞学发现(39.3%)。上皮异常包括非典型鳞状细胞(ASCUS, ASC-H),鳞状上皮内病变(LSIL, HSIL)和鳞状细胞癌,占总数的3.2%。LSIL占1.3%,HSIL占1.0%。单例SCC检出。宫颈上皮异常在印度女性中很常见。巴氏涂片是最方便和OPD检测上皮异常的早期阶段。应鼓励对巴氏涂片筛查的认识,以减少宫颈癌引起的发病率和死亡率。
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引用次数: 0
Oropharyngeal schwannoma- A relatively common entity at an uncommon site 口咽神经鞘瘤-一种在不常见部位的相对常见的实体
Pub Date : 2023-06-15 DOI: 10.18231/j.jdpo.2023.024
Garima Rawat, H. Aiyer, Anshuman Kumar, A. Sharma
Schwannomas are peripheral nerve sheath benign tumors which arise from the schwann cells. These neoplasms are most frequently seen in the 3 to 6 decade of life and affecting the limbs followed by head and neck region. Oropharyngeal vallecular involvement by schwannomas is extremely rarely reported in the previous literature. We report a case of a 25 year old male with lesion in the vallecula which was subsequently diagnosed as Schwannomas on histopathology.
神经鞘瘤是周围神经鞘良性肿瘤,起源于雪旺细胞。这些肿瘤最常见于30至60岁的生命,影响肢体,其次是头部和颈部。在以往的文献中,神经鞘瘤累及口咽小静脉的报道极为罕见。我们报告一例25岁男性的病变在小静脉,随后被诊断为神经鞘瘤的组织病理学。
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引用次数: 0
期刊
IP Journal of Diagnostic Pathology and Oncology
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