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Epidemiological Characteristic and Spatial Analysis of the Admission Rate of Hypertension in Zanjan Province, Iran 伊朗赞詹省高血压发病率的流行病学特征及空间分析
Q3 Medicine Pub Date : 2022-09-01 DOI: 10.30699/jambs.30.142.443
Mohsen Soleimani, A. Jalilvand, H. Ahangar
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引用次数: 0
An Exceptional Occurrence of Uterus Mullerian Adenosarcoma in a Young Iranian Woman 一名年轻伊朗妇女罕见的子宫穆勒管腺肉瘤
Q3 Medicine Pub Date : 2022-07-01 DOI: 10.30699/jambs.30.141.385
Fatemeh Samiee-Rad
A 24-year-old woman with menometrorrhagia for 8 months was referred without any personal risk factor and family history of malignancy. In the bimanual pelvic examination, the uterine indicated increased size. The ultrasound findings showed the enlargement of the uterus and a polypoid heterogeneous echo, M:53*40*20 mm. She underwent hysteroscopy polypectomy. Histopathological findings showed endometrial polyp.
一位24岁的女性月经过多8个月,在没有任何个人风险因素和恶性肿瘤家族史的情况下被转诊。在双手骨盆检查中,子宫显示增大。超声检查显示子宫增大,息肉样不均匀回声,M:53*40*20mm。她接受了宫腔镜息肉切除术。组织病理学表现为子宫内膜息肉。
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引用次数: 0
Epidemiology of Psychiatric Disorders among Children and Adolescents in Kohgiloyeh and Boyer- Ahmad Province, Iran 伊朗Kohkiloyeh和Boyer-Ahmad省儿童和青少年精神疾病流行病学
Q3 Medicine Pub Date : 2022-07-01 DOI: 10.30699/jambs.30.141.365
Nourrollah Yadegari, L. Jouybari, M. Fathi, Mohammad Reza Mohammadi, S. Mostafavi, A. Khaleghi, S. Elahi, Mohammad Reza Godarzi, Sajad Ramezani, Eshagh Karami, R. Ostovar
Background & Objective: Given the growing rate of psychiatric disorders, especially in young populations, detailed data on frequency of these disorders for further national public health strategiesis of great importance.We aimed to survey the frequency of different psychiatric disorders among children and adolescents in Kohgiloyeh and Boyer-Ahmad province. Materials & Methods: 20.5% (205 out of 1001) of studied cases showed at least one psychiatric disorder and 79.5 % showed no sign of any disorders. Anxiety disorders were the most frequent disorders (15.5%) followed by the behavioral disorders (7%), smoking and drug abuse (6%), behavioral disorders (2.4%) and neurodevelopmental disorders (2%), but no case was observed with psychosis. Results: Our study indicated that pretreatment of rats with KET, HAL and YOH abolished MPH induced - mood and motor activity disturbances. Conclusion: in comparison with other studies from Iran or other countries the prevalence of psychiatric disorders in Kohgiloyeh and Boyer-Ahmad is relatively high and special policies and efforts are suggested for enhancement of mental health values in this region.
背景与目的:鉴于精神疾病的发病率不断上升,尤其是在年轻人群中,关于这些疾病发生频率的详细数据对进一步制定国家公共卫生战略具有重要意义。我们旨在调查Kohgiloyeh和Boyer Ahmad省儿童和青少年中不同精神障碍的频率。材料与方法:20.5%(1001例中有205例)的研究病例至少有一种精神障碍,79.5%没有任何障碍迹象。焦虑障碍是最常见的障碍(15.5%),其次是行为障碍(7%)、吸烟和吸毒(6%)、行为障碍(2.4%)和神经发育障碍(2%),但没有观察到精神病病例。结果:KET、HAL和YOH预处理大鼠可消除MPH引起的情绪和运动活动障碍。结论:与伊朗或其他国家的其他研究相比,Kohkiloyeh和Boyer Ahmad的精神障碍患病率相对较高,建议采取特殊政策和努力提高该地区的精神健康价值。
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引用次数: 1
Description of the Clinical Course and Severity Score Progression in Critically Ill Children with Acute Bronchiolitis on High-Flow Nasal Cannula Support 高流量鼻插管支持下危重急性毛细支气管炎患儿的临床病程和严重程度评分进展的描述
Q3 Medicine Pub Date : 2022-07-01 DOI: 10.30699/jambs.30.141.340
Nelson M Durán Ochoa, Tammy Edel Nudelman, Hernando Mulett Hoyos, A. Bastidas, C. Diaz Ritter, J. Fernández-Sarmiento
10.30699/jambs.30.141.340 Background & Objective: Bronchiolitis is one of the main causes of morbidity and mortality in children. High-flow nasal cannulas (HFNCs) are an alternative for managing moderate to severe cases. Our aim was to describe the outcomes in critically ill children with bronchiolitis who receive HFNC support. Materials & Methods: This was a retrospective cohort study of critically ill children who had bronchiolitis and received HFNC support while hospitalized in the pediatric intensive care unit (PICU) between January 2013 and January 2020. The primary outcome was deterioration in the Wood-Downes scale. Secondary outcomes included length of hospitalization, duration of oxygen therapy, SpO2/FiO2, and the ROX index (respiratory rate – oxygenation). Results: During this period, 2,390 children were admitted, 87 of whom had bronchiolitis and met the inclusion criteria. The median age was 4.4 months (IQR: 2.4 – 8.6). In 87.3% of cases there was no worsening in the scale with the use of HFNCs. In the group that worsened, 79.3% had moderate and 20.7% severe bronchiolitis on admission, and they had a higher rate of congenital heart disease (p=0.03), chronic respiratory diseases (p=0.03) and neurological (p=0.05) diseases. At 12 hours, this group had a lower SpO2/FiO2 (< 180) and ROX index (< 4.0). None of the patients required mechanical ventilation. Conclusion: The use of HFNCs in children with moderate to severe bronchiolitis was associated with a modified clinical course, avoiding mechanical ventilation even in risk groups. SpO2/FiO2 and ROX index 12-hour cut-off points suggestive of patients with a delayed response to HFNC support were identified.
10.30699/jambs.30.141.340背景与目的:毛细支气管炎是儿童发病和死亡的主要原因之一。高流量鼻插管(HFNC)是治疗中度至重度病例的替代方案。我们的目的是描述接受HFNC支持的毛细支气管炎危重儿童的结果。材料与方法:这是一项对2013年1月至2020年1月在儿科重症监护室(PICU)住院期间患有细支气管炎并接受HFNC支持的危重儿童的回顾性队列研究。主要结果是Wood-Downes量表的恶化。次要结果包括住院时间、氧疗持续时间、SpO2/FiO2和ROX指数(呼吸频率-氧合)。结果:在此期间,共有2390名儿童入院,其中87人患有细支气管炎,符合纳入标准。中位年龄为4.4个月(IQR:2.4-8.6)。在87.3%的病例中,HFNCs的使用没有使量表恶化。在病情恶化的组中,79.3%的患者入院时患有中度细支气管炎,20.7%的患者患有严重细支气管炎,他们患有先天性心脏病(p=0.03)、慢性呼吸系统疾病(p=0.03)和神经系统疾病(p=0.05)的比率更高。12小时时,该组患者的SpO2/FiO2(<180)和ROX指数(<4.0)较低。无一例患者需要机械通气。结论:在中重度毛细支气管炎患儿中使用HFNCs与改变临床病程有关,即使在危险组中也要避免机械通气。确定了提示患者对HFNC支持反应延迟的SpO2/FiO2和ROX指数12小时截止点。
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引用次数: 0
Effects of Dill Extract on Blood Lipid Levels (TC, TG, LDL and HDL): A Systematic Review and Meta-Analysis 莳萝提取物对血脂水平(TC, TG, LDL和HDL)的影响:系统综述和荟萃分析
Q3 Medicine Pub Date : 2022-07-01 DOI: 10.30699/jambs.30.141.306
M. Azimi, M. Deldar, A. Moayeri, K. Sayehmiri
10.30699/jambs.30.141.306 Background & Objective: In recent years,there has been a growing trend towards the use of herbal medicine in the treatment and prevention of diseases. Blood lipid-lowering drugs have many side effects. On the other hand, various studies have reported the effect of dill ( Anethum graveolens ) on the reduction of blood lipids in different ways. This study aimed to evaluate the effect of dill on reducing the blood lipid levels. Materials & Methods: In this systematic review, 12 papers that evaluated the effect of dill on blood lipid levels up to the end of 2018 were studied using valid key words such as Lipid Profile, Dill ( Anethum graveolens ), and Hyperlipidemia in Pubmed, Medlib, Scopus, Sciencedirect, Embase, Google Scholar, Magiran, IranMedex, and SID. The results of the studies were combined using the random effects method of meta-analysis. The heterogeneity of studies was investigated using Q statistics and I 2 Index. Results: In 12 studies, the weighted mean differences (WMDs) of cholesterol reduction (TC) before and after intervention were estimated to be WMD = -19.22 mg / dl (95% CI: -30.68, -7.77), triglyceride, WMD = -25.47 mg / dl (95% CI: -49.28, -1.66) and low density lipoprotein (LDL), WMD = -14.01 mg / dl (95% CI: -22.14, -5.89) which were statistically significant ( p = 0.001). Meta-analysis after intervention in the case and placebo groups were (SMD=-2.71, 95% CI:-3.28,-1.06), for TC (SMD=-1.77, 95%CI:-2.71,-0.82) for TG and (SMD=-2.64, 95%CI:-3.88,-1.41)for LDL which indicated statistically significant reduction. Conclusion: Dill reduces cholesterol, triglyceride and low-density lipoprotein, but does not have a significant effect on high-density lipoprotein levels.
背景与目的:近年来,在治疗和预防疾病中使用草药的趋势日益增长。降血脂药物有很多副作用。另一方面,各种研究报道了莳萝(Anethum graveolens)以不同的方式降低血脂的作用。本研究旨在探讨莳萝对大鼠血脂水平的降低作用。材料与方法:本系统综述选取截至2018年底,在Pubmed、Medlib、Scopus、Sciencedirect、Embase、谷歌Scholar、Magiran、IranMedex、SID等数据库中使用有效关键词“脂质谱”、“莳乐(Anethum graveolens)”、“高脂血病”等评价莳乐对血脂水平影响的12篇论文进行研究。采用meta分析的随机效应方法对研究结果进行合并。采用Q统计和i2指数对研究的异质性进行调查。结果:在12项研究中,估计干预前后胆固醇降低(TC)的加权平均差值(WMD)为WMD = -19.22 mg / dl (95% CI: -30.68, -7.77),甘油三酯WMD = -25.47 mg / dl (95% CI: -49.28, -1.66),低密度脂蛋白WMD = -14.01 mg / dl (95% CI: -22.14, -5.89),差异均有统计学意义(p = 0.001)。干预后的荟萃分析,病例组和安慰剂组TC (SMD=-2.71, 95%CI: -3.28,-1.06)、TG (SMD=-1.77, 95%CI:-2.71,-0.82)、LDL (SMD=-2.64, 95%CI:-3.88,-1.41)均有统计学意义的降低。结论:莳萝可降低胆固醇、甘油三酯和低密度脂蛋白水平,但对高密度脂蛋白水平无显著影响。
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引用次数: 0
Evaluation of Global Longitudinal Strain Pattern (GLS) and Echocardiographic Parameters in the Sleeve Gastrectomy Patients Before and After Surgery 袖状胃切除术前后整体纵向应变图(GLS)和超声心动图参数的评价
Q3 Medicine Pub Date : 2022-07-01 DOI: 10.30699/jambs.30.141.327
Abdolvahab Baradaran, Somayeh Zamanifard, Maryam Parham, Farahnaz Nikdoust
10.30699/jambs.30.141.327 Background & Objective: Obesity is one of the problems associated with cardiovascular complications. Patients' heart function improves after sleeve gastrectomy. Global Longitudinal Strain (GLS) is one of the methods used to monitor heart function before and after sleeve gastrectomy. In this study, we evaluated the echocardiographic parameters pre and post sleeve gastrectomy. Materials & Methods: In this cross-sectional study, 22 patients including 17 female and 5 maleundergoing sleeve gastrectomy were studied. They had referred to Shariati Hospital in Tehran during 2019 – 2020. All patients underwent 2D echocardiography using speckle-tracking to evaluate left ventricular function and measure GLS. Results: Data analysis showed that GLS increased after surgery compared to preoperative period (15.4 ± 3.8 vs. 18.4 ± 3.04). Also, PAP, LVEDV, LVESV, LVDD, LVDS and AO were higher in the mentioned period; these findings were statistically significant (p-value <0.05). However, the RVSM mean, TAPSE, RVFAC and LVH parameters were higher post-surgery in comparison to the pre- surgery; a significant relationship was observed between the parameters before and after surgery. Conclusion: It can be concluded that GLS method, which evaluates echocardiographic parameters in obese patients undergoing sleeve gastrectomy can be highly significant in monitoring patients.
10.30699/jambs.30.141.327背景与目的:肥胖是与心血管并发症相关的问题之一。袖状胃切除术后患者的心脏功能得到改善。整体纵向应变(GLS)是袖状胃切除术前后监测心功能的方法之一。在本研究中,我们评估了袖状胃切除术前后的超声心动图参数。材料与方法:在这项横断面研究中,对22名接受袖状胃切除术的患者进行了研究,其中包括17名女性和5名男性。他们在2019年至2020年期间转诊至德黑兰Shariati医院。所有患者均采用斑点追踪二维超声心动图评估左心室功能并测量GLS。结果:术后GLS较术前升高(15.4±3.8 vs.18.4±3.04),PAP、LVEDV、LVESV、LVDD、LVDS、AO升高;这些结果具有统计学意义(p值<0.05)。然而,术后RVSM平均值、TAPSE、RVFAC和LVH参数高于术前;在手术前后观察到参数之间的显著关系。结论:GLS法评估袖状胃切除术后肥胖患者的超声心动图参数,对监测患者具有重要意义。
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引用次数: 1
Educational view of Pathological Fracture of Femur due to Hydatid Cysts: A Case Report and Review of Literature 女性棘球蚴病理性骨折的教育观——附1例报告及文献复习
Q3 Medicine Pub Date : 2022-07-01 DOI: 10.30699/jambs.30.141.374
Ramin Farzam, M. Abdi, Maryam Farhangi, M. Zibaei, H. Torkmandi
10.30699/jambs.30.141.374 Hydatid cysts can be caused by Echinococcus species in various tissues. Skeletal cystic lesions are very rare and may be neglected. Here, we report a case of pathologic fracture following primary hydatid cystic lesions in the proximal and femoral shaft bone. A 62-year-old man suffered a sudden fracture followed by swelling of the thigh. Intramedullary femoral fixation was made and during the surgery, numerous cystic lesions of the hydatid cysts were observed. After the surgery ultrasound and CT-Scans of the abdomen, lung, spine, and brain did not confirm any sign of mass or cyst elsewhere. The patient was followed up for one year. During this period, the union was not yet completely established and the patient was stillreceiving treatment. Orthopedic surgeons need to be aware of this parasitic complication in bones and joints and provide the best outcome for the patients with proper treatment. Surgery along with albendazole and/or mebendazole therapy remains the treatment of choice. For this purpose, it is recommended that attention be paid to long-term follow-up in continuous professional development courses.
包虫囊肿可由不同组织中的棘球蚴引起。骨骼囊性病变非常罕见,可能被忽视。在此,我们报告一例在股骨近端和股骨干发生原发性包虫囊性病变后的病理性骨折。一名62岁男子突然骨折,大腿肿胀。股骨髓内固定,术中观察到许多囊性病变的包虫囊肿。手术后,腹部、肺、脊柱和脑部的超声和ct扫描未发现任何肿块或囊肿的迹象。患者随访一年。在此期间,结合尚未完全建立,患者仍在接受治疗。骨科医生需要意识到这种寄生在骨骼和关节中的并发症,并通过适当的治疗为患者提供最好的结果。手术联合阿苯达唑和/或甲苯达唑治疗仍然是治疗的选择。为此目的,建议注意持续专业发展课程的长期后续行动。
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引用次数: 1
Comparison of the Effect of Cydonia oblonga and Phyllanthus Emblica on Gastric Residual Volume and Pulmonary Aspiration in Patients under Mechanical Ventilation in Mousavi Hospital ICU of Zanjan in 2020 2020年赞詹穆萨维医院ICU机械通气条件下冬凌草叶和余甘子对患者胃残积和肺抽吸的影响比较
Q3 Medicine Pub Date : 2022-07-01 DOI: 10.30699/jambs.30.141.357
Batool Dahar, Narjes Khavasi, K. Kamali, Vahideh Rashtchi
10.30699/jambs.30.141.357 Background & Objective: The gastric residual volume has a direct effect on the volume and timing of the subsequent feeding and causes gastric emptying and pulmonary aspiration. The present study compares the effect of Cydonia oblonga and Phyllanthus Emblica (Amla) fruit on gastric residual volume and pulmonary aspiration in mechanically- ventilated patients. Materials & Methods: This is a single-blind randomized clinical trial, including 48 patients (divided into three groups) under mechanical ventilation admitted to the intensive care unit (ICU) of Mousavi Hospital in Zanjan. Amla product and cydonia juice were gavaged in intervention groups A and, B, respectively. In all groups, the same gavage solution was prepared every three hours. Eventually, pulmonary secretion aspiration was measured (on the first, third and fifth days). Results: The difference of the mean gastric residual volume was not statistically significant in the intervention groups (on thefirst three days). The mean residual volume of the fourth and fifth days was statistically different and the rate of pulmonary aspiration in the intervention groups (on the fifth day) was significantly lower than the control group (P<0.001). The mean gastric residual volume of the two groups had no significant difference (P<0.471). Conclusion: The present study shows the effectiveness of cydonia juice and Amla on the gastric residual volume in patients admitted to ICU. The incidence of pulmonary aspiration in intervention groups has a decreasing trend (on the fifth day). Therefore, cydonia juice and Amla can be appropriate alternatives to chemical drugs.
10.30699/jambs.30.141.357背景与目的:胃残余容量直接影响后续进食的容量和时间,并导致胃排空和肺抽吸。本研究比较了冬凌和余甘子对机械通气患者胃残余容量和肺抽吸的影响。材料与方法:这是一项单盲随机临床试验,包括赞詹穆萨维医院重症监护室(ICU)接受机械通气的48名患者(分为三组)。分别在干预组A和B中灌胃Amla产品和cydonia果汁。在所有组中,每三小时制备一次相同的灌胃溶液。最后,测量肺分泌物抽吸(在第一天、第三天和第五天)。结果:干预组(前三天)的平均胃残留量差异无统计学意义。第4天和第5天的平均残留量有统计学差异,干预组(第5天)的肺抽吸率显著低于对照组(P<0.001)。两组的平均胃残留量无显著差异(P<0.471)ICU患者的胃残余容量。干预组的肺误吸发生率呈下降趋势(第5天)。因此,西冬凌草汁和Amla可以作为化学药物的合适替代品。
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引用次数: 0
Study of Pregnant Women Infected with COVID-19 During Pregnancy: A Case Report 孕妇妊娠期感染新冠肺炎的研究报告
Q3 Medicine Pub Date : 2022-07-01 DOI: 10.30699/jambs.30.141.379
F. Zare, S. Daliri, Sakineh Kolahdouzan, M. Rohani-Rasaf
This case study includes three pregnant women with COVID-19 diagnosed during pregnancy or delivery between March 28 and May 13, 2020. All cases were confirmed by a positive pharyngeal reverse transcription polymerase chain reaction (RT-PCR) test and one case by computed tomography scan (CT Scan) in addition to the (RT-PCR). Clinical and laboratory information was extracted from hospital records during pregnancy and delivery. The adverse effects during pregnancy and after the birth of the newborn, the possibility of vertical transmission from positive pregnant mothers to the neonates were investigated.Of the three women with COVID-19 infection, one patient was diagnosed two weeks before delivery and two were diagnosed during delivery and hospitalization. No adverse effects including preeclampsia, gestational hypertension, rupture of the amniotic sac during pregnancy and premature delivery were observed but one of the patients suffered from intrauterine fetal death (IUFD). in this study, adverse pregnancy outcome was not observed in pregnant women with Covid-19 infection based on hospital observations. No vertical transmission was observed following vaginal delivery or cesarean section and during pregnancy. As the effect of the virus on different people in society varies according to their individual characteristics, our conclusion in this study on pregnant women is also affected by these individual differences, which requires further studies in this field with more samples.
本案例研究包括三名在2020年3月28日至5月13日期间怀孕或分娩期间被诊断患有新冠肺炎的孕妇。所有病例均通过咽逆转录聚合酶链反应(RT-PCR)阳性检测得到证实,一例病例除通过(RT-PCR)外还通过计算机断层扫描(CT扫描)得到证实。临床和实验室信息是从怀孕和分娩期间的医院记录中提取的。研究了妊娠期间和新生儿出生后的不良反应,以及阳性孕妇向新生儿垂直传播的可能性。在三名感染新冠肺炎的女性中,一名患者在分娩前两周被确诊,两名患者在生产和住院期间被确诊。没有观察到包括先兆子痫、妊娠期高血压、妊娠期羊膜囊破裂和早产在内的不良反应,但其中一名患者患有宫内胎儿死亡(IUFD)。在这项研究中,根据医院观察,新冠肺炎感染孕妇未观察到不良妊娠结局。阴道分娩或剖宫产后及妊娠期间未观察到垂直传播。由于病毒对社会中不同人群的影响因其个体特征而异,我们在这项针对孕妇的研究中得出的结论也受到这些个体差异的影响,这需要在该领域进行更多样本的进一步研究。
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引用次数: 0
Evaluation of the Long-Term Survival in Non-Metastatic Young Breast Cancer Patients in South of Iran 伊朗南部非转移性年轻乳腺癌患者的长期生存评估
Q3 Medicine Pub Date : 2022-07-01 DOI: 10.30699/jambs.30.141.333
Behnam Kadkhodaei, A. Mosalaei, S. Omidvari, M. Ansari, M. Mohammadianpanah, N. Ahmadloo, H. Nasrollahi, Seyed Hasan Hamedi, M. Shariat, Mozhdeh Zamani
10.30699/jambs.30.141.333 Background & Objective: The lack of breast cancer screening in young women leads to late disease diagnosis and worse outcomes in this age group. This study was designed to evaluate clinicopathological features and long-term outcomes of young breast cancer women in south of Iran. Materials & Methods: This is a retrospective study of breast cancer patients who were pathologically diagnosed during 2005 to 2017. Data from 284 breast cancer patients aged 40 years or younger were included in this study. Demographic, clinicopathological properties as well as treatment modalities including type of surgery, adjuvant radiotherapy, and adjuvant or neoadjuvant chemotherapy were recorded and analyzed. Results: Median age of the patients was 36 (range 23-40) years. After a median follow-up of 68 months, 21 patients had died due to the disease, 59 patients were alive with the disease, and 204 patients were alive without the disease. The univariate COX regression demonstrated that the disease -free survival (DFS) was significantly low in patients who had undergone breast conservation surgery (BCS) and also patients with higher stages, estrogen/progesterone-negative and human epidermal growth factor receptor 2-positive (ER-/PR-/HER2+) status. Low overall survival (OS) was also significantly associated with stage. According to multivariate COX regression, BCS, stages II, III and also young age were independent predictive factors for low DFS. Conclusion: Given the aggressive features and worse outcome of young breast cancer patients, treatment remains tough and screening seems to be required at young age. Further studies are required to find best management and therapeutic protocols for these patients.
背景与目的:年轻女性缺乏乳腺癌筛查导致该年龄组疾病诊断较晚,预后较差。本研究旨在评估伊朗南部年轻乳腺癌妇女的临床病理特征和长期预后。材料与方法:本研究对2005 - 2017年病理诊断的乳腺癌患者进行回顾性研究。这项研究包括284名年龄在40岁或以下的乳腺癌患者的数据。记录和分析患者的人口学、临床病理特征以及治疗方式,包括手术类型、辅助放疗、辅助或新辅助化疗。结果:患者中位年龄为36岁(范围23-40岁)。中位随访68个月后,21例患者死于此病,59例患者存活,204例患者存活。单因素COX回归显示,接受乳房保护手术(BCS)的患者以及分期较高、雌激素/孕激素阴性和人表皮生长因子受体2阳性(ER-/PR-/HER2+)状态的患者的无病生存期(DFS)明显较低。低总生存期(OS)也与分期显著相关。多因素COX回归分析显示,BCS、II期、III期以及年龄是低DFS的独立预测因素。结论:考虑到年轻乳腺癌患者的侵袭性特征和较差的预后,治疗仍然困难,似乎需要在年轻时进行筛查。需要进一步的研究来为这些患者找到最佳的管理和治疗方案。
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引用次数: 1
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