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Social and economic patterning in UPF intake in toddlerhood and middle childhood: longitudinal data from the UK Gemini cohort.
IF 3.5 2区 医学 Q2 NUTRITION & DIETETICS Pub Date : 2025-01-10 DOI: 10.1016/j.jand.2025.01.004
Gabriella N Heuchan, Rana E Conway, Harry Tattan-Birch, Lisa Heggie, Clare H Llewellyn

Introduction: Children's consumption of ultra-processed food (UPF) may contribute to inequalities in obesity and wider health. Socioeconomic patterning in younger UK children's UPF intake is unknown.

Objective: To investigate socioeconomic patterning of UK toddlers' (21-months) and children's (7-years) UPF intake across several household and neighbourhood indicators.

Design: Secondary analysis of data from a prospective longitudinal cohort study using parent-report sociodemographic data and 3-day diet diaries.

Participants: /setting: Participants were children from the UK Gemini study of n=4,804 twins born in 2007. At 21-months and 7-years, n=2,591 and n=592 children had at least 2-days of dietary data, respectively.

Main outcome measures: Percentage energy from UPF at 21-months and 7-years-of-age, classified using the NOVA system.

Statistical analyses performed: Unadjusted linear regression models were run for household socioeconomic position (SEP) composite score, Index of multiple deprivation decile, income, occupation level, mother's age, education of mother and partner, child's ethnicity, sex, and age. Adjusted multivariable linear regression models were adjusted for ethnicity and all SEP indicators except SEP composite score (Adjusted 1), in addition to child sex and age (Adjusted 2). Missing data were addressed with multiple imputation and inverse probability weighting. Confidence intervals and P-values were adjusted to account for clustering within families.

Results: Children of lower SEP had higher UPF intake across several indicators. Mother's education was the strongest predictor, with postgraduate education associated with 8.64% (95% CI -12.08 to -5.20; P<0.001) and 10.12% (95% CI -15.68 to -4.56; P<0.001) less energy from UPF at 21-months and 7-years, respectively, compared to no educational qualifications in Adjusted model 2.

Conclusion: UK children from more disadvantaged backgrounds consumed a greater proportion of their energy from UPF. Mother's education seemed the most influential factor. Socioeconomic inequalities, particularly in maternal education, may drive disparities in diet quality and associated health outcomes. Addressing these gaps is essential to reduce childhood obesity and improve long-term health in socioeconomically disadvantaged populations.

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引用次数: 0
If not Food Deserts, then What? And, How will we Know?
IF 3.5 2区 医学 Q2 NUTRITION & DIETETICS Pub Date : 2025-01-10 DOI: 10.1016/j.jand.2025.01.005
Jacob Alex Klerman
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引用次数: 0
Effects of nutrition-specific interventions to prevent and control nutritional anemia in infants, children and adolescents: a systematic review and network meta-analysis of randomized controlled trials.
IF 3.5 2区 医学 Q2 NUTRITION & DIETETICS Pub Date : 2025-01-09 DOI: 10.1016/j.jand.2025.01.002
Ting Ren, Zhanjing Dai, Jing Yang, Yuhang Wu, Feng Chang, Sida Wang, Linyun Wang, Yuqiong Lu, Yun Lu
<p><strong>Background: </strong>Anemia is a prevalent health issue among children and adolescents worldwide, with malnutrition being one of the most common causes. Nutrition-related anemia can be prevented or controlled through targeted interventions.</p><p><strong>Objective: </strong>This study aimed to evaluate the effects of nutrition interventions on ferritin concentration, hemoglobin concentration, anemia prevalence, and nutritional anemia prevalence in infants, children, and adolescents-and to compare outcomes by intervention and age group using network meta-analysis of randomized controlled trials (RCTs).</p><p><strong>Methods: </strong>Web of Science, PubMed, Scopus, EBSCO, the Cochrane Library, CNKI, VIP Database, and WANFANG Database were comprehensively searched to identify RCTs on the effects of nutrition interventions (micronutrient supplementation, macronutrient supplementation, and nutrition education) until September 30, 2023. Two groups of researchers screened the literature and extracted data based on set inclusion and exclusion criteria. Reviewers used the Cochrane tool for assessing risk-of-bias in RCTs and used the Grading of Recommendations, Assessment, Development, and Evaluation for evaluating the strength of evidence for inclusion in network meta-analysis. The study population was categorized into infants and preschool children (6-59 months), school-aged children (6-11 years), and adolescents (12-18 years). The study evaluated the mean difference, risk ratio, and 95% credible interval of outcomes for each intervention across different age groups using network meta-analysis.</p><p><strong>Results: </strong>Sixty-one RCTs were included in this analysis. In network meta-analysis, micronutrient supplementation, macronutrient supplementation, and nutrition education were found to have significant effects on hemoglobin in infants and preschool children. Lipid-based nutrient supplementation resulted in the highest increase in hemoglobin, while multiple micronutrient supplementation resulted in the largest reduction in risk of anemia and iron deficiency anemia (IDA). In school-aged children, iron supplementation increased hemoglobin, while micronutrient supplementation also increased hemoglobin and reduced anemia risk. In adolescents, iron supplementation improved hemoglobin and lowered anemia risk.</p><p><strong>Conclusions: </strong>The effectiveness of nutrition interventions in improving nutritional anemia varies across intervention types and age groups. Micronutrient and iron supplementation consistently improved hemoglobin levels and related indicators, with evidence quality ranging from low to moderate. MMN and LNS had positive effects on hemoglobin and anemia in infants and preschool children, which is supported by low to moderate quality evidence. For adolescents, while micronutrient and iron supplementation showed positive effects, the overall evidence quality was generally low, highlighting the need for further high-qu
{"title":"Effects of nutrition-specific interventions to prevent and control nutritional anemia in infants, children and adolescents: a systematic review and network meta-analysis of randomized controlled trials.","authors":"Ting Ren, Zhanjing Dai, Jing Yang, Yuhang Wu, Feng Chang, Sida Wang, Linyun Wang, Yuqiong Lu, Yun Lu","doi":"10.1016/j.jand.2025.01.002","DOIUrl":"https://doi.org/10.1016/j.jand.2025.01.002","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;Anemia is a prevalent health issue among children and adolescents worldwide, with malnutrition being one of the most common causes. Nutrition-related anemia can be prevented or controlled through targeted interventions.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Objective: &lt;/strong&gt;This study aimed to evaluate the effects of nutrition interventions on ferritin concentration, hemoglobin concentration, anemia prevalence, and nutritional anemia prevalence in infants, children, and adolescents-and to compare outcomes by intervention and age group using network meta-analysis of randomized controlled trials (RCTs).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;Web of Science, PubMed, Scopus, EBSCO, the Cochrane Library, CNKI, VIP Database, and WANFANG Database were comprehensively searched to identify RCTs on the effects of nutrition interventions (micronutrient supplementation, macronutrient supplementation, and nutrition education) until September 30, 2023. Two groups of researchers screened the literature and extracted data based on set inclusion and exclusion criteria. Reviewers used the Cochrane tool for assessing risk-of-bias in RCTs and used the Grading of Recommendations, Assessment, Development, and Evaluation for evaluating the strength of evidence for inclusion in network meta-analysis. The study population was categorized into infants and preschool children (6-59 months), school-aged children (6-11 years), and adolescents (12-18 years). The study evaluated the mean difference, risk ratio, and 95% credible interval of outcomes for each intervention across different age groups using network meta-analysis.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;Sixty-one RCTs were included in this analysis. In network meta-analysis, micronutrient supplementation, macronutrient supplementation, and nutrition education were found to have significant effects on hemoglobin in infants and preschool children. Lipid-based nutrient supplementation resulted in the highest increase in hemoglobin, while multiple micronutrient supplementation resulted in the largest reduction in risk of anemia and iron deficiency anemia (IDA). In school-aged children, iron supplementation increased hemoglobin, while micronutrient supplementation also increased hemoglobin and reduced anemia risk. In adolescents, iron supplementation improved hemoglobin and lowered anemia risk.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusions: &lt;/strong&gt;The effectiveness of nutrition interventions in improving nutritional anemia varies across intervention types and age groups. Micronutrient and iron supplementation consistently improved hemoglobin levels and related indicators, with evidence quality ranging from low to moderate. MMN and LNS had positive effects on hemoglobin and anemia in infants and preschool children, which is supported by low to moderate quality evidence. For adolescents, while micronutrient and iron supplementation showed positive effects, the overall evidence quality was generally low, highlighting the need for further high-qu","PeriodicalId":379,"journal":{"name":"Journal of the Academy of Nutrition and Dietetics","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142969187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Home Visitation as an Intervention Opportunity to Prevent Childhood Obesity Within the First 2000 Days: A Scoping Review.
IF 3.5 2区 医学 Q2 NUTRITION & DIETETICS Pub Date : 2025-01-08 DOI: 10.1016/j.jand.2025.01.003
Jamie Zeldman, Danielle E Jake-Schoffman, Matthew J Gurka, Karla P Shelnutt, Amy R Mobley

Background: Home visitation programs are uniquely positioned to reach young children during the first 2000 days of life (ages 0 to 5 years), a critical time period to prevent childhood obesity.

Objective: This scoping review aimed to identify early childhood obesity prevention interventions implemented within home visitation during the first 2000 days of life, summarize outcomes assessed, and examine if and how nonmaternal caregivers and technology were included.

Methods: Guided by the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews, three databases (PubMed, Web of Science, CINAHL) were searched from January 1980 to June 2023 for obesity prevention interventions that utilized home visitation as a treatment modality, targeted children ≤5 years old, reported on child weight outcomes, were experimental or quasi-experimental designs with a control or comparison arm, and had full-text available in English. The quality and risk of bias of included studies were rated using the Academy of Nutrition and Dietetics' Quality Criteria Checklist for Primary Research.

Results: Of the 871 identified articles, 21 met inclusion criteria, and all reported at least one obesogenic behavioral outcome in the intervention group compared to the control group. Intervention duration ranged from 4 months to 3 years, and frequency of home visits varied from weekly, biweekly, monthly, or a designated number of home visits within a defined time frame. Three interventions partnered with an established home visiting program, but home visits in all interventions were conducted by either professional or paraprofessional individuals. Nine of the 21 studies targeted other caregivers in addition to the mother and 12 of 21 incorporated a form of technology.

Conclusions: Several different early childhood obesity prevention interventions have been implemented within home visitation during the first 2000 days of life. Future research is needed to investigate the effectiveness of these interventions on weight- and behavioral-related outcomes, as well as explore the impacts of the interventionist type, program duration, inclusion of nonmaternal caregivers, and use of technology on childhood obesity-related outcomes.

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引用次数: 0
Opportunities in programs and policies to address the underlying drivers of sugary drink and water consumption in the Washington DC metro area: a qualitative community-based system dynamics approach.
IF 3.5 2区 医学 Q2 NUTRITION & DIETETICS Pub Date : 2025-01-07 DOI: 10.1016/j.jand.2025.01.001
Michelle Estradé, Yeeli Mui, Lillian Witting, Rosalina Burgos-Gil, Larissa Calancie, Joel Gittelsohn, Uriyoán Colón-Ramos

Background: Though the Dietary Guidelines for Americans recommend that individuals drink water instead of sugar-sweetened beverages (SSBs), this behavior is influenced and reinforced by a complex network of structures and systems.

Objective: The objectives of this study were to develop a shared understanding among multiple stakeholders about the structural and underlying, interconnected drivers of SSB and water consumption in the Washington D.C. metro area and to have them identify feasible and impactful policy levers.

Design: A community-based system dynamics approach was used during a 2-day group model building workshop where stakeholders engaged to develop a shared visual representation of the underlying, interconnected drivers of SSB and water intake and to identify what they thought were impactful and feasible policy levers.

Participants/setting: Stakeholders were purposively recruited from diverse sectors (early childhood education (n=6), nutrition assistance programs (n=2), food policy council and advocacy groups (n=4), city government officials including municipal water (n=4), and food and beverage retail (n=1)) to participate in a group model building workshop in July of 2022 in Washington, D.C.

Analysis: Using member checking and iterative feedback, the research team synthesized the outputs from the workshop into one causal loop diagram and ranked policy levers.

Results: Stakeholders visualized 7 subsystems that drive water and SSB consumption, then identified and ranked 5 policy levers by potential impact and ease of implementation, including 1) increase public health spending (high impact/hard to do); 2) invest in new and updated infrastructure for public water (high impact/hard to do); 3) implement coordinated public health campaigns to promote drinking safe, palatable water as an alternative to SSB (low impact/easy to do); 4) provision of tap water filters (low impact/easy to do); and 5) limits on SSB marketing (high impact/debated easy-or-hard to do).

Conclusions: This participatory approach allowed stakeholders to envision multiple places to intervene in the system simultaneously to both decrease SSB and increase water consumption in the specific context of their community.

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引用次数: 0
Association Between the Nutritional Quality of Food Purchases and Household Food at Home Expenditures in Mexico. 墨西哥购买食品的营养质量与家庭居家食品支出之间的关系。
IF 3.5 2区 医学 Q2 NUTRITION & DIETETICS Pub Date : 2025-01-01 Epub Date: 2024-07-04 DOI: 10.1016/j.jand.2024.07.002
Néstor A Sánchez-Ortiz, Carolina Batis, Analí Castellanos-Gutiérrez, M Arantxa Colchero

Background: Poor-quality diets are a major risk factor for noncommunicable diseases. Few studies in Mexico have tested whether higher expenditures are needed to purchase high-quality food.

Objective: The objective of the study was to assess how dietary quality of food purchases was associated with household food at home expenditures.

Design: This study was a secondary analysis of cross-sectional data from the National Household Income and Expenditure Survey (EncuestaNacional de Ingresos y Gastos de los Hogares [ENIGH] 2018).

Participants/setting: The study included 74 469 households with information on food and beverage purchases in Mexico in 2018.

Main outcome measures: Quarterly household food at home expenditures by adult equivalent (AE) for all food groups that were scored with the Global Dietary Quality Score (GDQS) for food purchases expressed in dollars/quarterly/AE.

Statistical analyses performed: Adjusted generalized linear models were used to evaluate the association between GDQS for food purchases (expressed in tertiles: low, mid, and high) and quarterly food expenditures. The analyses were performed at the national level by place of residence and income quintile.

Results: At the national level, the difference in food expenditures between the high- and the low-GDQS groups was +$13.85/AE. By place of residence, the difference between the high- and the low-GDQS groups was +$17.31/AE in urban and +$5.12/AE in rural areas. For income quintile 1 (lowest), there was a statistical difference of -$4.79/AE and +$43.25 for quintile 5 (highest).

Conclusions: Quality of food purchases can be associated with higher or lower expenditures depending on the specific food purchased. High GDQS is associated with lower expenditures among the lowest-income households as they purchase less expensive options compared with high-income households.

背景:劣质饮食是非传染性疾病的主要风险因素。在墨西哥,很少有研究检验购买高质量食品是否需要更高的支出:本研究的目的是评估购买食品的膳食质量与家庭食品支出之间的关系:本研究是对全国家庭收入和支出调查(ENIGH 2018)横截面数据的二次分析:研究包括74469个家庭,这些家庭在2018年有在墨西哥购买食品和饮料的信息.主要结果测量:按成人当量(AE)计算的所有食品类别的季度家庭食品支出,在全球膳食质量评分(GDQS)中对食品购买进行评分,以美元/季度/AE表示:使用调整后的广义线性模型来评估全球膳食质量评分(GDQS)中食品购买量(以三等分表示:低、中、高)与季度食品支出之间的关联。分析在全国范围内按居住地和收入五分位数进行:在全国范围内,高 GDQS 组和低 GDQS 组的食品支出差异为 +13.85美元/AE。从居住地来看,高 GDQS 组和低 GDQS 组之间的差异在城市地区为 +17.31美元/AE,在农村地区为 +5.12美元/AE。收入五等分层 1(最低)的统计差异为-4.79 美元/等值,五等分层 5(最高)的统计差异为+43.25 美元/等值:购买食品的质量与支出的高低有关,这取决于所购买的具体食品。与高收入家庭相比,最低收入家庭购买价格较低的食品,因此 GDQS 高与他们的支出较低有关。
{"title":"Association Between the Nutritional Quality of Food Purchases and Household Food at Home Expenditures in Mexico.","authors":"Néstor A Sánchez-Ortiz, Carolina Batis, Analí Castellanos-Gutiérrez, M Arantxa Colchero","doi":"10.1016/j.jand.2024.07.002","DOIUrl":"10.1016/j.jand.2024.07.002","url":null,"abstract":"<p><strong>Background: </strong>Poor-quality diets are a major risk factor for noncommunicable diseases. Few studies in Mexico have tested whether higher expenditures are needed to purchase high-quality food.</p><p><strong>Objective: </strong>The objective of the study was to assess how dietary quality of food purchases was associated with household food at home expenditures.</p><p><strong>Design: </strong>This study was a secondary analysis of cross-sectional data from the National Household Income and Expenditure Survey (EncuestaNacional de Ingresos y Gastos de los Hogares [ENIGH] 2018).</p><p><strong>Participants/setting: </strong>The study included 74 469 households with information on food and beverage purchases in Mexico in 2018.</p><p><strong>Main outcome measures: </strong>Quarterly household food at home expenditures by adult equivalent (AE) for all food groups that were scored with the Global Dietary Quality Score (GDQS) for food purchases expressed in dollars/quarterly/AE.</p><p><strong>Statistical analyses performed: </strong>Adjusted generalized linear models were used to evaluate the association between GDQS for food purchases (expressed in tertiles: low, mid, and high) and quarterly food expenditures. The analyses were performed at the national level by place of residence and income quintile.</p><p><strong>Results: </strong>At the national level, the difference in food expenditures between the high- and the low-GDQS groups was +$13.85/AE. By place of residence, the difference between the high- and the low-GDQS groups was +$17.31/AE in urban and +$5.12/AE in rural areas. For income quintile 1 (lowest), there was a statistical difference of -$4.79/AE and +$43.25 for quintile 5 (highest).</p><p><strong>Conclusions: </strong>Quality of food purchases can be associated with higher or lower expenditures depending on the specific food purchased. High GDQS is associated with lower expenditures among the lowest-income households as they purchase less expensive options compared with high-income households.</p>","PeriodicalId":379,"journal":{"name":"Journal of the Academy of Nutrition and Dietetics","volume":" ","pages":"99-108.e12"},"PeriodicalIF":3.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141544353","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Systems Thinking and Sustainable Food Systems in Dietetics Education: A Survey of Directors. 营养学教育中的系统思维和可持续食品系统:主任调查。
IF 3.5 2区 医学 Q2 NUTRITION & DIETETICS Pub Date : 2025-01-01 Epub Date: 2024-07-02 DOI: 10.1016/j.jand.2024.06.233
Erin E Bergquist, Lyndi Buckingham-Schutt, Christina Gayer Campbell, Awoke Dollisso, Shuyang Qu, Angela M Tagtow, Scott Smalley
<p><strong>Background: </strong>Systems thinking is recommended, but not required, for teaching food and water system sustainability in nutrition and dietetics education.</p><p><strong>Objective: </strong>This study investigated systems thinking and sustainable, resilient, and healthy food and water systems (SRHFWS) in nutrition and dietetics programs. It examined program directors' practices, values, attitudes, confidence levels, and the relationships between systems thinking, teaching SRHFWS topics, confidence levels, and years of experience as a dietitian and program director.</p><p><strong>Design: </strong>Conducted in September 2022, the study used a descriptive design with a validated 20-item Systems Thinking Scale and a researcher-designed survey with 1-5 Likert-type scales.</p><p><strong>Participants and setting: </strong>The online survey was distributed to 611 Accreditation Council for Education in Nutrition and Dietetics program directors, with a 27% (N = 163) response.</p><p><strong>Statistical analysis: </strong>Descriptive statistics (frequency or mean ± SD) were calculated using Excel. Inferential statistics were examined using R. Analysis of variance was used to compare experience as a registered dietitian nutritionist and experience as a program director to confidence levels in teaching each SRHFWS topic. Linear regression was used determine the relationship between total Systems Thinking Scale score and demographic and programmatic variables.</p><p><strong>Results: </strong>Seventy-seven percent of program directors scored high on the Systems Thinking Scale (mean score = 65.2 ± 8.4 on a 0 to 80 scale), and more than 85% of directors agreed that including systems thinking in dietetics was important. However, only 32.1% reported teaching systems thinking. Less than half of program directors agreed that systems thinking was adequately addressed in Accreditation Council for Education in Nutrition and Dietetics standards, and nearly 80% of program directors agreed there was room to strengthen systems thinking content. Directors neither agreed nor disagreed there are adequate Accreditation Council for Education in Nutrition and Dietetics standards addressing SRHFWS and reported SRHFWS topics were inconsistently taught. Confidence levels were lowest for teaching economic and environmental topics. Awareness and use of resources developed by the Academy of Nutrition and Dietetics Foundation was low.</p><p><strong>Conclusions: </strong>Integration of systems thinking in nutrition and dietetics education presents promising opportunities to address complexity in the field. Applying systems thinking to teach SRHFWS may narrow the disparity between educators' perceived importance and program coverage. Enhancing program directors' awareness and utilization of Academy of Nutrition and Dietetics Foundation resources and improved alignment between practice standards and accreditation standards may empower program directors to use systems thinking
背景:建议在营养与营养学教育中教授食物与水系统的可持续性时采用系统思维,但并非必需:本研究调查了营养与营养学课程中的系统思维与可持续、有弹性和健康的食物与水系统(SRHFWS)。研究考察了项目主任的实践、价值观、态度、信心水平,以及系统思维、SRHFWS主题教学、信心水平、营养师和项目主任工作年限之间的关系:该研究于 2022 年 9 月进行,采用描述性设计,使用经过验证的 20 个项目的系统思维量表(STS)和研究人员设计的 1-5 个李克特量表进行调查:在线调查的对象是611名营养与饮食教育认证委员会(ACEND)的项目主任,回复率为27%(n=163):使用 Excel 计算描述性统计(频率、平均值、标准差)。方差分析用于比较作为营养师和项目主任的经验与教授每个 SRHFWS 主题的信心水平。线性回归用于确定 STS 总分与人口统计学变量和项目变量之间的关系:77%的项目主任在 STS 中得分较高(平均分 65.2,0-80 分,SD 8.4),85% 以上的主任认为在营养学中纳入系统思维非常重要。然而,只有 32.1%的人表示教授过系统思维。不到一半的项目主任认为 ACEND 标准中充分涉及了系统思考,近 80% 的项目主任认为系统思考的内容还有待加强。主任们既不同意也不反对 ACEND 标准充分涉及 SRHFWS,并报告 SRHFWS 主题的教学不一致。对经济和环境主题教学的信心水平最低。对营养与饮食学院基金会开发的资源的认识和使用程度较低:将系统思维融入营养与饮食学教育为解决该领域的复杂性提供了大有可为的机会。应用系统思维教授 SRHFWS 可以缩小教育者认为的重要性与课程覆盖面之间的差距。提高项目主任对基金会资源的认识和利用,改善实践标准与认证标准之间的一致性,可使项目主任有能力运用系统思维教授营养与饮食学中与可持续性相关的挑战。
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引用次数: 0
Coffee, Phosphoinositide 3-Kinase Signaling Pathway, and Prostate Cancer: A Prospective Study in the Health Professionals Follow-Up Study. 咖啡、PI3K 信号通路与前列腺癌:健康专业人员随访研究中的一项前瞻性研究。
IF 3.5 2区 医学 Q2 NUTRITION & DIETETICS Pub Date : 2025-01-01 Epub Date: 2024-07-04 DOI: 10.1016/j.jand.2024.07.001
Rui Song, Konrad H Stopsack, Junkun Ren, Lorelei A Mucci, Steven K Clinton, Massimo Loda, Molin Wang, Edward L Giovannucci, Kathryn M Wilson, Stephanie A Smith-Warner

Background: Higher coffee intake has been associated with reduced risk of prostate cancer, particularly aggressive forms. The activation of the phosphoinositide 3-kinase (PI3K) signaling pathway plays an important role in prostate carcinogenesis.

Objective: To evaluate associations between prediagnostic coffee intake and a PI3K activation score, the expression/presence of PI3K regulators, and downstream effectors in tumor tissue from men with prostate cancer in the Health Professionals Follow-Up Study, a prospective cohort study conducted in the United States.

Design: A case-only study design was applied. Coffee intake was assessed using validated food frequency questionnaires completed in 1986 and every 4 years thereafter until prostate cancer diagnosis.

Participants setting: Study participants comprised 1242 men diagnosed with prostate cancer from 1986 to 2009 and with tumor markers assessed from tissue microarrays constructed from tumor specimens.

Main outcome measures: The outcomes include the PI3K activation score; expression of insulin receptor and insulin-like growth factor 1 receptor; angiogenesis markers; and presence of the tumor suppressor phosphatase and tensin homolog, chronic and acute inflammation, simple atrophy, and post-atrophic hyperplasia.

Statistical analyses performed: Multivariable linear or logistic regression was conducted to estimate associations between coffee intake and tumor marker expression/presence.

Results: Among coffee drinkers (86.6% of the population), median (25th, 75th percentile) coffee intake was 2 c/day (1, 3 c/day). The associations between coffee consumption and the tumor markers of interest were generally weak with modest precision. When comparing men who drank >3 c/day coffee with nondrinkers, the absolute percent difference in the PI3K activation score and angiogenesis markers ranged from 0.6% to 3.6%. The odds ratios for phosphatase and tensin homolog loss, insulin-like growth factor 1 receptor and insulin receptor expression, and presence of chronic and acute inflammation, simple atrophy, and postatrophic hyperplasia also were not statistically significant, were imprecise, and ranged from 0.82 to 1.58.

Conclusions: Coffee intake was not observed to be associated with PI3K activation, related regulators, and several effectors in prostate tumor tissue. Studies exploring alternative pathways or earlier steps in carcinogenesis are needed to investigate the underlying mechanisms of the coffee and prostate cancer association.

背景:咖啡摄入量越高,患前列腺癌(尤其是侵袭性前列腺癌)的风险越低。PI3K 信号通路的激活在前列腺癌的发生中起着重要作用:目的:在美国进行的前瞻性队列研究 "健康专业人员随访研究"(Health Professionals Follow-up Study)中,评估诊断前咖啡摄入量与前列腺癌男性患者肿瘤组织中 PI3K 激活评分、PI3K 调节因子和下游效应因子的表达/存在之间的关系:设计:采用病例研究设计。咖啡摄入量通过 1986 年完成的有效食物频率问卷进行评估,此后每四年评估一次,直至确诊前列腺癌:研究参与者包括1986年至2009年期间确诊为前列腺癌的1242名男性,其肿瘤标志物由肿瘤标本的组织芯片进行评估:结果包括PI3K激活评分、胰岛素受体和IGF1受体的表达、血管生成标志物、肿瘤抑制因子PTEN的存在、慢性和急性炎症、单纯萎缩和萎缩后增生:进行了多变量线性或逻辑回归,以估计咖啡摄入量与肿瘤标志物表达/存在之间的关联:结果:在咖啡饮用者(占总人口的86.6%)中,咖啡摄入量的中位数(第25-75位)为2(1-3)杯/天。咖啡摄入量与相关肿瘤标志物之间的关系普遍较弱,精确度不高。当将每天喝咖啡超过 3 杯的男性与不喝咖啡的男性进行比较时,PI3K 激活评分和血管生成标志物的绝对百分比差异从 0.6% 到 3.6% 不等。PTEN缺失、IGF1受体和胰岛素受体表达、存在慢性和急性炎症、单纯萎缩和萎缩后增生的几率比也没有统计学意义,不精确,在0.82到1.58之间:在前列腺肿瘤组织中,未观察到咖啡摄入与PI3K活化、相关调节因子和几种效应因子有关。要研究咖啡与前列腺癌关系的潜在机制,还需要探索其他途径或致癌过程中的更早步骤。
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引用次数: 0
Reliability and Validity of Diabetes Nutrition Self-Efficacy and Behavior Measures for the "What Can I Eat" Diabetes Nutrition Education Program for American Indian and Alaska Native Adults With Type 2 Diabetes. 针对患有 2 型糖尿病的美国印第安人和阿拉斯加原住民成年人的 "我能吃什么 "糖尿病营养教育计划的糖尿病营养自我效能和行为测量的可靠性和有效性。
IF 3.5 2区 医学 Q2 NUTRITION & DIETETICS Pub Date : 2025-01-01 Epub Date: 2024-05-10 DOI: 10.1016/j.jand.2024.05.004
Angela G Brega, Sarah A Stotz, Kelly R Moore, Monica C McNulty, Luohua Jiang

Background: American Indian and Alaska Native (AI/AN) people have high rates of diabetes and limited access to nutrition education. The "What Can I Eat? Healthy Choices for People With Type 2 Diabetes" (WCIE) diabetes nutrition education program was culturally adapted for AI/AN adults.

Objective: This analysis was designed to evaluate the reliability and validity of items developed to measure diabetes nutrition self-efficacy (ie, confidence one can engage in specific behaviors) and diabetes nutrition behavior among participants in the WCIE program for AI/AN adults.

Design: This study was a secondary analysis of data from a randomized controlled trial designed to evaluate the WCIE program for AI/AN adults. Baseline data were used to assess the reliability and validity of the self-efficacy and behavior items, which were collected via survey. Due to COVID-19 safety protocols, the intervention was conducted via Zoom (Zoom Video Communications), and both survey and clinical data were collected at home by participants.

Participants/setting: The study was conducted from January to December 2021 with 5 AI/AN-serving health care programs in Oklahoma, Illinois, North Carolina, California, and New York. AI/AN adults with type 2 diabetes who spoke English and had internet access were eligible. Sixty people participated.

Main outcome measures: Analyses examined validity and reliability of diabetes nutrition self-efficacy and behavior items.

Statistical analysis performed: To test reliability, internal consistency and factor structures of the scales were examined. To evaluate convergent validity, Pearson correlations were computed to examine the association of the self-efficacy and behavior measures with each other and with clinical indicators (ie, body mass index, blood pressure, and hemoglobin A1c).

Results: Two self-efficacy factors were identified. Each showed strong internal consistency (Cronbach α ≥ 0.85; McDonald ω ≥ 0.88) and was directly associated with diabetes nutrition behavior (P < .001). The factor assessing Confidence in Using the Diabetes Plate was inversely associated with hemoglobin A1c (Pearson correlation = -0.32, P = .0243). The behavior measure capturing Healthy Nutrition Behavior showed strong internal consistency (α = 0.89; ω = 0.92) and was inversely associated with hemoglobin A1c (Pearson correlation = -0.38, P = .0057).

Conclusions: Diabetes nutrition self-efficacy and behavior items developed for the WCIE program for AI/AN adults are valid and reliable. These items can facilitate rigorous and consistent evaluation of the AI/AN WCIE program.

背景:美国印第安人和阿拉斯加原住民(AI/AN)的糖尿病发病率很高,但接受营养教育的机会却很有限。我可以吃什么?(WCIE) 糖尿病营养教育计划针对美国印第安人和阿拉斯加原住民成年人进行了文化调整:本分析旨在评估为衡量糖尿病营养自我效能(即对自己能够从事特定行为的信心)和糖尿病营养行为而开发的项目的可靠性和有效性:本研究是对一项随机对照试验数据的二次分析,该试验旨在评估针对亚裔美国人/印第安人成人的 WCIE 计划。基线数据用于评估通过调查收集的自我效能和行为项目的可靠性和有效性。根据 COVID-19 安全协议,干预是通过 Zoom 进行的,调查和临床数据都是由参与者在家中收集的:该研究于 2021 年 1 月至 12 月在俄克拉荷马州、伊利诺伊州、北卡罗来纳州、加利福尼亚州和纽约州的五个为亚裔美国人/印第安人服务的医疗保健项目中进行。会说英语并能上网的 2 型糖尿病亚裔/非裔成人符合条件。有 60 人参与:对糖尿病营养自我效能和行为项目的有效性和可靠性进行了分析:为测试信度,研究了量表的内部一致性和因子结构。为评估收敛效度,计算了皮尔逊相关性,以检查自我效能和行为测量之间以及与临床指标(即体重指数、血压、血红蛋白 A1C)之间的关联:结果:确定了两个自我效能因子。每个因子都显示出很强的内部一致性(Cronbach alphas ≥ 0.85;McDonald omegas ≥ 0.88),并与糖尿病营养行为直接相关(Ps < 0.001)。评估使用糖尿病餐盘信心的因子与 A1C 成反比(Pearson Correlation = -0.32,P = 0.0243)。捕捉健康营养行为的行为测量显示出很强的内部一致性(α = 0.89;Ω = 0.92),并且与 A1C 呈反比关系(Pearson Correlation = - 0.38,P = 0.0057):结论:为美国印第安人/美洲印第安人成人 WCIE 计划开发的糖尿病营养自我效能和行为项目是有效和可靠的。这些项目有助于对阿拉斯加原住民/印第安人 WCIE 计划进行严格、一致的评估。
{"title":"Reliability and Validity of Diabetes Nutrition Self-Efficacy and Behavior Measures for the \"What Can I Eat\" Diabetes Nutrition Education Program for American Indian and Alaska Native Adults With Type 2 Diabetes.","authors":"Angela G Brega, Sarah A Stotz, Kelly R Moore, Monica C McNulty, Luohua Jiang","doi":"10.1016/j.jand.2024.05.004","DOIUrl":"10.1016/j.jand.2024.05.004","url":null,"abstract":"<p><strong>Background: </strong>American Indian and Alaska Native (AI/AN) people have high rates of diabetes and limited access to nutrition education. The \"What Can I Eat? Healthy Choices for People With Type 2 Diabetes\" (WCIE) diabetes nutrition education program was culturally adapted for AI/AN adults.</p><p><strong>Objective: </strong>This analysis was designed to evaluate the reliability and validity of items developed to measure diabetes nutrition self-efficacy (ie, confidence one can engage in specific behaviors) and diabetes nutrition behavior among participants in the WCIE program for AI/AN adults.</p><p><strong>Design: </strong>This study was a secondary analysis of data from a randomized controlled trial designed to evaluate the WCIE program for AI/AN adults. Baseline data were used to assess the reliability and validity of the self-efficacy and behavior items, which were collected via survey. Due to COVID-19 safety protocols, the intervention was conducted via Zoom (Zoom Video Communications), and both survey and clinical data were collected at home by participants.</p><p><strong>Participants/setting: </strong>The study was conducted from January to December 2021 with 5 AI/AN-serving health care programs in Oklahoma, Illinois, North Carolina, California, and New York. AI/AN adults with type 2 diabetes who spoke English and had internet access were eligible. Sixty people participated.</p><p><strong>Main outcome measures: </strong>Analyses examined validity and reliability of diabetes nutrition self-efficacy and behavior items.</p><p><strong>Statistical analysis performed: </strong>To test reliability, internal consistency and factor structures of the scales were examined. To evaluate convergent validity, Pearson correlations were computed to examine the association of the self-efficacy and behavior measures with each other and with clinical indicators (ie, body mass index, blood pressure, and hemoglobin A1c).</p><p><strong>Results: </strong>Two self-efficacy factors were identified. Each showed strong internal consistency (Cronbach α ≥ 0.85; McDonald ω ≥ 0.88) and was directly associated with diabetes nutrition behavior (P < .001). The factor assessing Confidence in Using the Diabetes Plate was inversely associated with hemoglobin A1c (Pearson correlation = -0.32, P = .0243). The behavior measure capturing Healthy Nutrition Behavior showed strong internal consistency (α = 0.89; ω = 0.92) and was inversely associated with hemoglobin A1c (Pearson correlation = -0.38, P = .0057).</p><p><strong>Conclusions: </strong>Diabetes nutrition self-efficacy and behavior items developed for the WCIE program for AI/AN adults are valid and reliable. These items can facilitate rigorous and consistent evaluation of the AI/AN WCIE program.</p>","PeriodicalId":379,"journal":{"name":"Journal of the Academy of Nutrition and Dietetics","volume":" ","pages":"78-89.e1"},"PeriodicalIF":3.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11550264/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140911536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Body Weight Perceptions Among Youth From 6 Countries and Associations With Social Media Use: Findings From the International Food Policy Study. 六个国家的青少年对体重的看法及其与社交媒体使用的关系:国际食品政策研究的结果。
IF 3.5 2区 医学 Q2 NUTRITION & DIETETICS Pub Date : 2025-01-01 Epub Date: 2024-06-26 DOI: 10.1016/j.jand.2024.06.223
Karen Hock, Lana Vanderlee, Christine M White, David Hammond

Background: Body dissatisfaction is associated with poor psychological and physical health, particularly among young people. However, limited data exist on body size perceptions across countries and factors associated with dissatisfaction.

Objective: This study examined dissatisfaction prevalence and associations with sociodemographics and social media use among youth in 6 countries.

Design: Repeat cross-sectional national online surveys were conducted as part of the 2019 and 2020 International Food Policy Study Youth Survey.

Participants: The sample included 21 277 youth aged 10 to 17 years from Australia, Canada, Chile, Mexico, the United Kingdom, and the United States. Youth were recruited to complete the online survey through parents/guardians enrolled in the Nielsen Consumer Insights Global Panel and their partners' panels.

Main outcome measures: Figural drawing scales assessed self-perceived and ideal body images, with differences between scales representing body dissatisfaction.

Statistical analyses performed: Multinomial logistic regression models examined differences in body dissatisfaction by country, and associations with sociodemographics and either social media screen time or platforms used, including 2-way interactions with country.

Results: Overall, approximately 45% of youth reported the same perceived and ideal body sizes, whereas 35% were "larger than ideal" (from 33% in Canada and Australia to 42% in Chile) and 20% were "thinner than ideal" (from 15% in Chile to 22% in Mexico). Greater social media screen time was associated with a higher likelihood of moderate-severe dissatisfaction for being "thinner than ideal" and at least mild dissatisfaction for being "larger than ideal" (P < .003 for all contrasts), with greater dissatisfaction among users of YouTube and Snapchat than nonusers (P ≤ .005 for both contrasts). Modest differences in body dissatisfaction between countries were observed for age, ethnicity, body mass index, and weight-based teasing.

Conclusions: Body dissatisfaction is prevalent among youth across diverse countries. These findings highlight the need to promote healthy body image in youth, particularly among social media users.

背景:身体不满意与心理和身体健康状况不佳有关,尤其是在年轻人当中。然而,关于各国对身体尺寸的看法以及与不满意相关因素的数据却很有限:本研究调查了六个国家的年轻人对身体不满意的普遍程度以及与社会人口统计学和社交媒体使用的关系:作为 2019 年和 2020 年国际食品政策研究青年调查的一部分,进行了重复的横断面国家在线调查:样本包括来自澳大利亚、加拿大、智利、墨西哥、英国和美国的 21277 名 10-17 岁青少年。通过尼尔森消费者洞察全球小组及其合作伙伴小组中注册的父母/监护人招募青少年完成在线调查:图画量表评估自我感觉和理想的身体形象,量表之间的差异代表身体不满意度:多项式逻辑回归模型检验了不同国家的身体不满意度差异,以及与社会人口统计学、社交媒体 "屏幕时间 "或使用平台的关联,包括与国家的双向交互作用:总体而言,约 45% 的青少年报告了相同的认知体型和理想体型,35% 的青少年报告了 "比理想体型大"(从加拿大和澳大利亚的 33% 到智利的 42%),20% 的青少年报告了 "比理想体型瘦"(从智利的 15% 到墨西哥的 22%)。社交媒体屏幕时间越长,"比理想体型瘦 "的中度-严重不满意度越高,"比理想体型大 "的至少轻度不满意度越高(p 结论:身体不满意在不同国家的青少年中普遍存在。这些发现凸显了在青少年中,尤其是在社交媒体用户中推广健康身体形象的必要性。
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引用次数: 0
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Journal of the Academy of Nutrition and Dietetics
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