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Does Elevated Alcohol Consumption Delay the Diagnostic Assessment of Cognitive Impairment among Older Adults? 饮酒增加会延迟老年人认知障碍的诊断评估吗?
IF 2.3 Q2 Medicine Pub Date : 2022-02-07 DOI: 10.1159/000521924
Ben Kamsvaag, K. Tevik, J. Šaltytė Benth, Bei Wu, S. Bergh, G. Selbaek, A. Helvik
Introduction: The time from symptom debut to assessment of cognitive impairment (TSA) is usually substantial, and many factors can influence the length of this interval. Our objective was to discern whether elevated alcohol consumption is associated with TSA. Methods: Alcohol consumption was measured among 3,236 older Norwegians assessed for cognitive impairment. Elevated consumption was defined as drinking 4–7 times a week. TSA was defined as the number of months between symptom debut and assessment. The association between alcohol consumption and TSA was examined with a multiple regression analysis controlled for sociodemographic and clinical covariates. Results: Mean (SD) and median TSA were 34.8 (35.8) and 24.0 months, respectively. Elevated alcohol consumption was not associated with TSA. Longer TSA was associated with being male, having a high education level, being retired or unemployed, being single, having low scores on the Mini-Mental State Examination (MMSE) or Personal Activities of Daily Living (PADL), having high subsyndrome scores of depression or agitation on The Neuropsychiatric Inventory – Questionnaire (NPI-Q), or having a spouse/cohabitant as the designated next of kin. Conclusion: This study indicates that elevated alcohol consumption does not influence TSA. Possible explanations are discussed, but further research is needed to determine the effect of alcohol definitively. We did identify other novel characteristics associated with TSA which may be important in minimizing the risk of delayed cognitive assessments and should be kept in mind when considering assessment.
引言:从出现症状到评估认知障碍(TSA)的时间通常很长,许多因素会影响这一间隔的长度。我们的目的是了解饮酒量增加是否与TSA有关。方法:对3236名接受认知障碍评估的挪威老年人的饮酒量进行测量。高消费被定义为每周饮酒4-7次。TSA被定义为症状出现和评估之间的月数。通过对社会人口统计学和临床协变量进行控制的多元回归分析,检验了饮酒量与TSA之间的相关性。结果:平均(SD)和TSA中位数分别为34.8(35.8)和24.0个月。饮酒量增加与TSA无关。TSA时间较长与男性、高教育水平、退休或失业、单身、迷你精神状态检查(MMSE)或日常生活个人活动(PADL)得分低、神经精神问卷(NPI-Q)抑郁或躁动亚综合征得分高有关,或者有配偶/同居者作为指定的近亲。结论:本研究表明,饮酒量增加不会影响TSA。讨论了可能的解释,但还需要进一步的研究来确定酒精的影响。我们确实发现了与TSA相关的其他新特征,这些特征可能对最大限度地减少延迟认知评估的风险很重要,在考虑评估时应牢记。
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引用次数: 1
The Assessments of Music Therapy for Dementia Based on the Cochrane Review 基于Cochrane综述的音乐治疗对痴呆的评价
IF 2.3 Q2 Medicine Pub Date : 2022-01-21 DOI: 10.1159/000521231
Makiko Abe, K. Tabei, M. Satoh
Background: Research on music therapy for dementia has taken a variety of measures and has been slow to consolidate evidence. Examining the outcomes that are currently being investigated and the measures that have been used can be useful for future research on music therapy for dementia. Objectives: This study used cited original papers from a review in the Cochrane Database of Systematic Reviews to determine if there are items that should be measured or scales that should be used in conducting research on music therapy for dementia. The rating scales used and the outcomes examined were extracted. Method: We used Dodd’s criteria to identify (1) the outcome domains examined in music therapy for dementia, (2) the measures used, and (3) the measures capable of detecting significant intervention effects. Result: A search for reviews was conducted, and 7 systematic reviews (78 articles) were identified. Among them, 30 articles met the inclusion criteria. The 30 articles examined 18 of the 38 items in Dodd’s outcome categories, while 20 items were not examined, and 78 different survey methods were used. The items most frequently surveyed in the studies were psychiatric outcomes, cognitive functioning, and global quality of life general outcomes. Conclusions: We found that many studies investigated cognitive function, behavioral and psychological symptoms of dementia (BPSD), and quality of life; compared to BPSD, various types of rating scales were used for cognitive function. By standardizing the rating scales, we can contribute to the accumulation of evidence for music therapy for dementia.
背景:音乐治疗痴呆症的研究采取了多种措施,但证据的巩固进展缓慢。检查目前正在调查的结果和已经使用的措施,可以对未来痴呆症音乐治疗的研究有用。目的:本研究引用了Cochrane系统评价数据库中的一篇综述中的原始论文,以确定在进行痴呆症音乐治疗研究时,是否有应该测量的项目或应该使用的量表。提取使用的评分量表和检查的结果。方法:我们使用多德标准来确定(1)痴呆症音乐治疗中检查的结果领域,(2)使用的措施,以及(3)能够检测显著干预效果的措施。结果:检索了7篇系统综述(78篇文章)。其中,30篇文章符合入选标准。这30篇文章检查了多德结果类别中38个项目中的18个,而20个项目没有检查,并使用了78种不同的调查方法。研究中最常调查的项目是精神结果、认知功能和全球生活质量的总体结果。结论:我们发现许多研究调查了痴呆症(BPSD)的认知功能、行为和心理症状以及生活质量;与BPSD相比,不同类型的评定量表用于认知功能。通过标准化评分量表,我们可以为痴呆症音乐治疗的证据积累做出贡献。
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引用次数: 3
Demographic Data Differences in Perceived Control over Nursing Practice among Nurses Caring for Nursing Home Residents 疗养院住客护理人员护理实践控制知觉的人口统计学差异
IF 2.3 Q2 Medicine Pub Date : 2022-01-17 DOI: 10.1159/000521284
Mohammad J Rababa, Shatha Al-Sabbah, Dania Bani Hamad
Introduction: Control over nursing practice is crucial for improved quality of life for nursing home (NH) residents. Nevertheless, little is known about the association of nurses’ demographic data with their perceived control over nursing practice in Jordan and beyond. Therefore, this study aimed at examining the differences in nurses’ levels of perceived control over nursing practice based on their demographic characteristics. Methods: This descriptive-correlational study was conducted on a convenience sample of 163 nurses caring for NH residents. Nurses’ perceived control over nursing practice was measured by the Control Over Nursing Practice (CONP) scale. Results: The participating nurses were found to have low levels of perceived control over nursing practice which varied between the nurse groups according to gender, level of experience, and type of NHs. Discussion/Conclusion: This study is the first quantitative study to examine association between nurses’ demographic characteristics, such as age or years of nursing experience, and their perceived control over nursing practice. Despite the preliminary findings of this study, the findings of this study provide a better understanding of the impact of nurses’ sociodemographic and professional characteristics on their levels of perceived control over nursing practice.
导言:控制护理实践是至关重要的,以提高生活质量的养老院(NH)居民。然而,很少有人知道护士的人口统计数据与他们的感知控制护理实践在约旦和超越的关联。因此,本研究旨在调查护士在人口统计学特征的基础上对护理实践的感知控制水平的差异。方法:本描述性相关研究采用方便抽样163名护理住院病人的护士进行。采用护理实践控制量表(CONP)测量护士对护理实践的感知控制。结果:参与的护士对护理实践的感知控制水平较低,根据性别、经验水平和NHs类型,护士组之间存在差异。讨论/结论:本研究是第一个定量研究护士人口统计学特征(如年龄或护理经验)与他们对护理实践的感知控制之间关系的研究。尽管本研究的初步发现,本研究的结果提供了一个更好的理解护士的社会人口学和专业特征的影响,对护理实践的感知控制水平。
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引用次数: 0
Pronoun Use among Caregivers of People Living with Dementia: Associations with Dementia Severity Using Text Analysis of a Natural Language Sample. 痴呆症患者护理人员的代词使用:使用自然语言样本的文本分析与痴呆症严重程度的关联。
IF 2.3 Q2 Medicine Pub Date : 2022-01-01 DOI: 10.1159/000522122
Alissa Bernstein Sideman, Jenna L Wells, Jennifer Merrilees, Suzanne M Shdo, Claire I Yee, Katherine L Possin, Robert W Levenson

Introduction: Family caregivers of persons living with dementia (PLWDs) have extensive social, physical, emotional, and financial responsibilities. However, less is known about the relationship and interpersonal connection between caregivers and PLWDs. We examined caregiver pronoun use, as an index of the connection between the caregiver and PLWD and its associations with the caregiver's and PLWD's health and well-being.

Methods: Caregivers of PLWDs (N = 320) were asked to describe a recent time they felt connected to the PLWD in their care. Responses were transcribed and coded to quantify pronoun use by category (we-pronouns, I-pronouns, and they-pronouns). Caregivers also reported on their depression, burden, and the PLWD's dementia severity and marital satisfaction. Sixty-eight caregivers repeated the same survey 24 months after the initial survey.

Results: Caregivers used less we-pronouns when the PLWD's dementia was more severe, at both timepoints. Spousal caregivers used more we-pronouns and less I- and they-pronouns than nonspousal caregivers. There was an interaction between spousal relationship and dementia severity, such that spousal caregivers exhibited a stronger negative association between dementia severity and we-pronoun use. There were no associations between pronoun category and caregiver burden or depression.

Discussion: Caregivers may feel increasingly disconnected from the PLWD as their dementia becomes more severe, as reflected by less we-pronoun usage. This study highlights the opportunity to explore relationship connection through text analysis.

痴呆症患者的家庭照顾者承担着广泛的社会、身体、情感和经济责任。然而,对照顾者与plwd之间的关系和人际关系了解较少。我们检查了照顾者代词的使用,作为照顾者和PLWD之间的联系的一个指标,以及它与照顾者和PLWD的健康和福祉的关联。方法:要求PLWD的护理人员(N = 320)描述最近一次他们在护理中感到与PLWD有联系。对回答进行转录和编码,以按类别(we-代词、i -代词和they-代词)量化代词的使用。照顾者也报告了他们的抑郁、负担、老年痴呆症的严重程度和婚姻满意度。68名护理人员在最初调查的24个月后重复了同样的调查。结果:在两个时间点,当PLWD的痴呆更严重时,护理人员使用的我们代词更少。配偶照顾者比非配偶照顾者使用更多的“我们”代词和更少的“我和他们”代词。配偶关系与痴呆严重程度之间存在交互作用,配偶照顾者在痴呆严重程度与我们代词的使用之间表现出更强的负相关。代词类别与照顾者负担或抑郁之间没有关联。讨论:随着痴呆症变得越来越严重,护理人员可能会感到与PLWD越来越脱节,这反映在我们代词的使用上。本研究强调了通过文本分析来探索关系联系的机会。
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引用次数: 1
Googling Alzheimer Disease: An Infodemiological and Ecological Study. 谷歌阿尔茨海默病:一项信息流行病学和生态学研究。
IF 2.3 Q2 Medicine Pub Date : 2021-12-27 eCollection Date: 2021-09-01 DOI: 10.1159/000520692
Bernadeth Lyn C Piamonte, Veeda Michelle M Anlacan, Roland Dominic G Jamora, Adrian I Espiritu

Introduction: Understanding the emergent role of the internet on the health-seeking behavior of people is critical not only in the areas of medicine and public health but also in the field of infodemiology.

Methods: Using Google Trends, data on global search queries for Alzheimer disease (AD) between January 2004 and April 2021 were analyzed. The relationship between online interest, as reflected by search volume index (SVI), and measures of disease burden, namely prevalence, deaths, and disability-adjusted life years, was evaluated.

Results: There was a reduction in the tendency to search for AD during the past two decades. SVI peaks corresponded to news of famous people with AD and awareness months. Symptoms, causes, and differences with the term dementia were central queries for persons interested in AD. No notable overall correlation between SVI and measures of disease burden was found due to competing results. Sub-group analyses, however, showed that these correlations may be influenced by socioeconomic development, with strong negative significant associations observed in lower middle-income countries.

Conclusion: Online interest in AD may represent a more complex metric influenced by socioeconomic factors. Awareness of the impact of celebrity diagnosis and awareness months on online search behavior may prove useful in the planning of public health campaigns for AD.

引言:了解互联网对人们寻求健康行为的新兴作用,不仅在医学和公共卫生领域,而且在信息流行病学领域都是至关重要的。方法:利用Google Trends对2004年1月至2021年4月全球阿尔茨海默病(AD)搜索查询数据进行分析。通过搜索量指数(SVI)反映的在线兴趣与疾病负担指标(即患病率、死亡率和残疾调整生命年)之间的关系进行了评估。结果:在过去的二十年中,搜索AD的趋势有所减少。SVI峰值与名人患AD的新闻和认知月相对应。症状、病因和与痴呆的差异是对AD感兴趣的人的中心问题。由于结果相互矛盾,SVI和疾病负担测量之间没有发现显著的总体相关性。然而,亚组分析表明,这些相关性可能受到社会经济发展的影响,在中低收入国家观察到强烈的显著负相关。结论:网上对AD的兴趣可能是一个更复杂的指标,受社会经济因素的影响。认识到名人诊断和意识月对在线搜索行为的影响,可能有助于规划针对阿尔茨海默病的公共卫生运动。
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引用次数: 6
A Review of Functional Neuroimaging in People with Down Syndrome with and without Dementia. 唐氏综合征伴及不伴痴呆患者的功能神经影像学研究综述。
IF 2.3 Q2 Medicine Pub Date : 2021-12-27 eCollection Date: 2021-09-01 DOI: 10.1159/000520880
Funmi Deinde, Jay Kotecha, Lilian Suh Lih Lau, Sagnik Bhattacharyya, Latha Velayudhan

Background: Individuals with Down syndrome (DS) are at high risk of dementia which is difficult to diagnose in DS. Neuroimaging has been identified as a potential tool to aid diagnosis by detecting changes in brain function. We carried out a review comparing functional neuroimaging in DS individuals with and without dementia.

Summary: A literature search was conducted using PubMed to identify relevant studies. In DS subjects with dementia, fluorodeoxyglucose-positron emission tomography (PET) studies showed glucose hypometabolism particularly in the parietal and/or temporal regions whilst magnetic resonance spectroscopy studies showed increased myoinositol and decreased N-acetylaspartate. Ligand-based PET studies revealed significant Pittsburgh compound B binding in DS subjects over the age of 40, particularly if they had dementia.

Key messages: Neuroimaging may aid the early detection of dementia in DS; however, further longitudinal studies are required.

背景:唐氏综合征(DS)患者发生痴呆的风险高,且痴呆的诊断难度大。神经成像已经被认为是一种潜在的工具,可以通过检测大脑功能的变化来帮助诊断。我们进行了一项综述,比较了伴有和不伴有痴呆的退行性痴呆患者的功能神经影像学。摘要:通过PubMed进行文献检索,找出相关研究。在患有痴呆症的DS受试者中,氟脱氧葡萄糖正电子发射断层扫描(PET)研究显示葡萄糖代谢低下,特别是在顶叶和/或颞区,而磁共振波谱研究显示肌醇增加,n -乙酰天冬氨酸减少。基于配体的PET研究显示,在40岁以上的DS受试者中,匹兹堡化合物B结合显著,特别是如果他们患有痴呆症。关键信息:神经影像学可能有助于退行性痴呆的早期发现;然而,还需要进一步的纵向研究。
{"title":"A Review of Functional Neuroimaging in People with Down Syndrome with and without Dementia.","authors":"Funmi Deinde,&nbsp;Jay Kotecha,&nbsp;Lilian Suh Lih Lau,&nbsp;Sagnik Bhattacharyya,&nbsp;Latha Velayudhan","doi":"10.1159/000520880","DOIUrl":"https://doi.org/10.1159/000520880","url":null,"abstract":"<p><strong>Background: </strong>Individuals with Down syndrome (DS) are at high risk of dementia which is difficult to diagnose in DS. Neuroimaging has been identified as a potential tool to aid diagnosis by detecting changes in brain function. We carried out a review comparing functional neuroimaging in DS individuals with and without dementia.</p><p><strong>Summary: </strong>A literature search was conducted using PubMed to identify relevant studies. In DS subjects with dementia, fluorodeoxyglucose-positron emission tomography (PET) studies showed glucose hypometabolism particularly in the parietal and/or temporal regions whilst magnetic resonance spectroscopy studies showed increased myoinositol and decreased N-acetylaspartate. Ligand-based PET studies revealed significant Pittsburgh compound B binding in DS subjects over the age of 40, particularly if they had dementia.</p><p><strong>Key messages: </strong>Neuroimaging may aid the early detection of dementia in DS; however, further longitudinal studies are required.</p>","PeriodicalId":38017,"journal":{"name":"Dementia and Geriatric Cognitive Disorders Extra","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2021-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/b7/7b/dee-0011-0324.PMC8787537.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39882853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Translation, Cross-Cultural Adaptation, and Validation of the Portuguese Version of the Rotterdam Elderly Pain Observation Scale. 鹿特丹老年人疼痛观察量表葡萄牙语版的翻译、跨文化适应和验证。
IF 2.3 Q2 Medicine Pub Date : 2021-12-20 eCollection Date: 2021-09-01 DOI: 10.1159/000520455
Julieta Seixas-Moizes, Anneke Boerlage, Érica Negrini Lia, Lucas Emmanuel Lopes E Santos, Miriane Lucindo Zucoloto, Fabíola Dach, Priscila Colavite Papassidero, Laís Almeida Leal Wichert-Ana, Oscar Della Pasqua, Marianne Louise Wiesebron, Tatiana Reis Icuma, Vera Lucia Lanchote, Eduardo Barbosa Coelho, Dick Tibboel, Lauro Wichert-Ana

Introduction: This study reports on the translation, cultural adaptation, and validation of a Portuguese version of the Rotterdam Elderly Pain Observation Scale (REPOS), a Dutch scale to assess pain in patients who cannot communicate, with or without dementia.

Methods: This is a multicenter study in pain and neurological units involving Brazil (clinical phase) and the Netherlands (training phase). We performed a retrospective cross-sectional, 2-staged analysis, translating and culturally adapting the REPOS to a Portuguese version (REPOS-P) and evaluating its psychometric properties. Eight health professionals were trained to observe patients with low back pain. REPOS consists of 10 behavioral items scored as present or absent after a 2-min observation. The REPOS score of ≥3 in combination with the Numerical Rating Scale (NRS) of ≥4 indicated pain. The Content Validity Index (CVI) in all items and instructions showed CVI values at their maximum. According to the higher correlation coefficient found between NRS and REPOS-P, it may be suggested that there was an adequate convergent validity.

Results: The REPOS-P was administered to 80 patients with a mean age of 60 years (SD 11.5). Cronbach's alpha coefficient showed a moderate internal consistency of REPOS-P (α = 0.62), which is compatible with the original study of REPOS. All health professionals reached high levels of interrater agreement within a median of 10 weeks of training, assuring reproducibility. Cohen's kappa was 0.96 (SD 0.03), and the intraclass correlation coefficient was 0.98 (SD 0.02), showing high reliability of REPOS-P scores between the trainer (researcher) and the trainees (healthcare professionals). The Pearson correlation coefficient was 0.95 (95% confidence interval 0.94-0.97), showing a significant correlation between the total scores of REPOS-P and NRS.

Conclusion: The REPOS-P was a valuable scale for assessing elderly patients with low back pain by different healthcare professionals. Short application time, ease of use, clear instructions, and the brief training required for application were essential characteristics of REPOS-P.

本研究报告了葡萄牙语版鹿特丹老年疼痛观察量表(REPOS)的翻译、文化适应和验证,REPOS是一种荷兰语量表,用于评估患有或不患有痴呆症的无法沟通的患者的疼痛。方法:这是一项涉及巴西(临床阶段)和荷兰(训练阶段)的疼痛和神经学单位的多中心研究。我们进行了回顾性的横断面两阶段分析,将REPOS翻译成葡萄牙语版本(REPOS- p)并进行文化调整,并评估其心理测量特性。八名卫生专业人员接受了培训,以观察腰痛患者。REPOS由10个行为项目组成,经过2分钟的观察,得分为存在或不存在。REPOS评分≥3分结合NRS评分≥4分提示疼痛。所有项目和说明书的内容效度指数(Content Validity Index, CVI)均达到最大值。NRS与REPOS-P之间存在较高的相关系数,说明NRS与REPOS-P具有足够的收敛效度。结果:80例患者接受reposp治疗,平均年龄60岁(SD 11.5)。Cronbach’s alpha系数显示REPOS- p具有中等的内部一致性(α = 0.62),这与REPOS的原始研究相一致。所有卫生专业人员在培训的中位数10周内达到了较高水平的人员间一致性,确保了可重复性。Cohen’s kappa为0.96 (SD 0.03),类内相关系数为0.98 (SD 0.02),表明培训师(研究者)与学员(医护人员)之间的REPOS-P评分具有较高的信度。Pearson相关系数为0.95(95%可信区间0.94 ~ 0.97),REPOS-P总分与NRS总分相关性显著。结论:REPOS-P量表是一种有价值的评估老年人腰痛的量表。REPOS-P的基本特点是应用时间短、使用方便、说明书清晰、应用培训时间短。
{"title":"Translation, Cross-Cultural Adaptation, and Validation of the Portuguese Version of the Rotterdam Elderly Pain Observation Scale.","authors":"Julieta Seixas-Moizes,&nbsp;Anneke Boerlage,&nbsp;Érica Negrini Lia,&nbsp;Lucas Emmanuel Lopes E Santos,&nbsp;Miriane Lucindo Zucoloto,&nbsp;Fabíola Dach,&nbsp;Priscila Colavite Papassidero,&nbsp;Laís Almeida Leal Wichert-Ana,&nbsp;Oscar Della Pasqua,&nbsp;Marianne Louise Wiesebron,&nbsp;Tatiana Reis Icuma,&nbsp;Vera Lucia Lanchote,&nbsp;Eduardo Barbosa Coelho,&nbsp;Dick Tibboel,&nbsp;Lauro Wichert-Ana","doi":"10.1159/000520455","DOIUrl":"https://doi.org/10.1159/000520455","url":null,"abstract":"<p><strong>Introduction: </strong>This study reports on the translation, cultural adaptation, and validation of a Portuguese version of the Rotterdam Elderly Pain Observation Scale (REPOS), a Dutch scale to assess pain in patients who cannot communicate, with or without dementia.</p><p><strong>Methods: </strong>This is a multicenter study in pain and neurological units involving Brazil (clinical phase) and the Netherlands (training phase). We performed a retrospective cross-sectional, 2-staged analysis, translating and culturally adapting the REPOS to a Portuguese version (REPOS-P) and evaluating its psychometric properties. Eight health professionals were trained to observe patients with low back pain. REPOS consists of 10 behavioral items scored as present or absent after a 2-min observation. The REPOS score of ≥3 in combination with the Numerical Rating Scale (NRS) of ≥4 indicated pain. The Content Validity Index (CVI) in all items and instructions showed CVI values at their maximum. According to the higher correlation coefficient found between NRS and REPOS-P, it may be suggested that there was an adequate convergent validity.</p><p><strong>Results: </strong>The REPOS-P was administered to 80 patients with a mean age of 60 years (SD 11.5). Cronbach's alpha coefficient showed a moderate internal consistency of REPOS-P (α = 0.62), which is compatible with the original study of REPOS. All health professionals reached high levels of interrater agreement within a median of 10 weeks of training, assuring reproducibility. Cohen's kappa was 0.96 (SD 0.03), and the intraclass correlation coefficient was 0.98 (SD 0.02), showing high reliability of REPOS-P scores between the trainer (researcher) and the trainees (healthcare professionals). The Pearson correlation coefficient was 0.95 (95% confidence interval 0.94-0.97), showing a significant correlation between the total scores of REPOS-P and NRS.</p><p><strong>Conclusion: </strong>The REPOS-P was a valuable scale for assessing elderly patients with low back pain by different healthcare professionals. Short application time, ease of use, clear instructions, and the brief training required for application were essential characteristics of REPOS-P.</p>","PeriodicalId":38017,"journal":{"name":"Dementia and Geriatric Cognitive Disorders Extra","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2021-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/04/e0/dee-0011-0314.PMC8787539.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39882850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prediction of Postoperative Delirium after Gastrointestinal Surgery Using the Mie Constructional Apraxia Scale. 用Mie构念失用量表预测胃肠手术后谵妄。
IF 2.3 Q2 Medicine Pub Date : 2021-12-09 eCollection Date: 2021-09-01 DOI: 10.1159/000520249
Yosuke Tenpaku, Masayuki Satoh, Kenji Kato, Kazuhisa Fujinaga, Yuji Haruki, Hiroki Nakahashi, Keisuke Morikawa, Yasunori Imaoka, Hiroyuki Takemura, Hiroshi Tatsumi

Background: Postoperative delirium (POD) is a transient postoperative complication that occurs after surgical procedures. Risk factors reported for POD include dementia and cognitive decline. The purpose of this study was to identify predictors of POD by examining the use of preoperative neuropsychological tests, including the Mie Constructional Apraxia Scale (MCAS), and patient background factors.

Method: The study was performed as a retrospective cohort study. The subjects were 33 patients (mean age, 75.8 ± 10.9 years; male:female ratio, 26:7) who underwent gastrointestinal surgery at Matsusaka City Hospital between December 2019 and April 2021. Data were collected retrospectively from medical records. The study was started after receiving approval from the institution's ethics committee. The survey items included general patient information, nutritional assessment, surgical information, and neuropsychological tests. Subjects were classified into 2 groups according to the presence or absence of POD. If a significant difference was observed between the 2 groups, the sensitivity, specificity, and area under the curve were calculated using a receiver operating characteristic (ROC) curve.

Result: There were 10 patients in the POD group (male:female ratio, 6:4) and 23 patients in the non-POD group (20:3). The POD group had a shorter education history (p = 0.047) and significantly higher MCAS scores (p = 0.007) than the non-POD group. The ROC curve showed a sensitivity of 90%, a specificity of 69%, and an area under the curve of 0.798 when the MCAS cutoff value was set at 3 points.

Conclusion: Preoperative MCAS results were capable of predicting the occurrence of POD after gastrointestinal surgery. In addition, a relatively short education background was also considered a risk factor for POD.

背景:术后谵妄(POD)是手术后一过性并发症。据报道,POD的危险因素包括痴呆和认知能力下降。本研究的目的是通过检查术前神经心理测试的使用,包括Mie构念失用量表(MCAS)和患者背景因素,来确定POD的预测因素。方法:采用回顾性队列研究。研究对象33例,平均年龄75.8±10.9岁;男女比例为26:7),他们于2019年12月至2021年4月在松坂市医院接受了胃肠手术。资料回顾性收集自医疗记录。这项研究是在获得该机构伦理委员会的批准后开始的。调查项目包括患者一般信息、营养评估、手术信息和神经心理测试。根据有无POD分为两组。如果观察到两组之间存在显著差异,则使用受试者工作特征(ROC)曲线计算敏感性、特异性和曲线下面积。结果:POD组10例(男女比例为6:4),非POD组23例(男女比例为20:3)。POD组受教育历史较短(p = 0.047), MCAS评分显著高于非POD组(p = 0.007)。当MCAS截止值设为3点时,ROC曲线的灵敏度为90%,特异性为69%,曲线下面积为0.798。结论:术前MCAS结果可预测胃肠手术后POD的发生。此外,相对较短的教育背景也被认为是POD的危险因素。
{"title":"Prediction of Postoperative Delirium after Gastrointestinal Surgery Using the Mie Constructional Apraxia Scale.","authors":"Yosuke Tenpaku,&nbsp;Masayuki Satoh,&nbsp;Kenji Kato,&nbsp;Kazuhisa Fujinaga,&nbsp;Yuji Haruki,&nbsp;Hiroki Nakahashi,&nbsp;Keisuke Morikawa,&nbsp;Yasunori Imaoka,&nbsp;Hiroyuki Takemura,&nbsp;Hiroshi Tatsumi","doi":"10.1159/000520249","DOIUrl":"https://doi.org/10.1159/000520249","url":null,"abstract":"<p><strong>Background: </strong>Postoperative delirium (POD) is a transient postoperative complication that occurs after surgical procedures. Risk factors reported for POD include dementia and cognitive decline. The purpose of this study was to identify predictors of POD by examining the use of preoperative neuropsychological tests, including the Mie Constructional Apraxia Scale (MCAS), and patient background factors.</p><p><strong>Method: </strong>The study was performed as a retrospective cohort study. The subjects were 33 patients (mean age, 75.8 ± 10.9 years; male:female ratio, 26:7) who underwent gastrointestinal surgery at Matsusaka City Hospital between December 2019 and April 2021. Data were collected retrospectively from medical records. The study was started after receiving approval from the institution's ethics committee. The survey items included general patient information, nutritional assessment, surgical information, and neuropsychological tests. Subjects were classified into 2 groups according to the presence or absence of POD. If a significant difference was observed between the 2 groups, the sensitivity, specificity, and area under the curve were calculated using a receiver operating characteristic (ROC) curve.</p><p><strong>Result: </strong>There were 10 patients in the POD group (male:female ratio, 6:4) and 23 patients in the non-POD group (20:3). The POD group had a shorter education history (<i>p</i> = 0.047) and significantly higher MCAS scores (<i>p</i> = 0.007) than the non-POD group. The ROC curve showed a sensitivity of 90%, a specificity of 69%, and an area under the curve of 0.798 when the MCAS cutoff value was set at 3 points.</p><p><strong>Conclusion: </strong>Preoperative MCAS results were capable of predicting the occurrence of POD after gastrointestinal surgery. In addition, a relatively short education background was also considered a risk factor for POD.</p>","PeriodicalId":38017,"journal":{"name":"Dementia and Geriatric Cognitive Disorders Extra","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2021-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/9f/12/dee-0011-0306.PMC8740234.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39862102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
One-Year Change in Locus of Control among People with Dementia. 痴呆症患者控制感的一年变化。
IF 2.3 Q2 Medicine Pub Date : 2021-12-07 eCollection Date: 2021-09-01 DOI: 10.1159/000520248
Ingeborg Halse, Guro Hanevold Bjørkløf, Knut Engedal, Geir Selbæk, Maria Lage Barca

Introduction: Knowledge of how perceptions of personal control change over time may provide valuable insights into how people cope with having dementia. The present study aimed to examine change in locus of control over a 12-month period in persons with dementia.

Method: The study included 52 participants with dementia. Locus of control was measured with the Locus of Control of Behavior Scale (LoCB), with higher scores indicating a more external locus of control, interpreted as perceiving less personal control. A ≥5% change on the LoCB was considered clinically meaningful. We recorded sociodemographic characteristics and assessed dementia severity, cognition, ability to function independently in daily activities and physical self-maintenance, depressive symptomatology, and number of prescribed medications. Analyses were performed to examine differences between those with increases (more external) or decreases (less external) in the LoCB score after 12 months and to examine associations between baseline variables and change in the LoCB score.

Results: The mean LoCB score for the total sample did not change after 12 months (baseline mean 29.33 vs. follow-up mean 30.33, p = 0.553); however, 2 subgroups emerged. Using the ≥5% cutoff revealed that the LoCB score changed for 92.3% of the sample, becoming less external (lower LoCB) for 21 participants and more external (higher LoCB) for 27 participants. At baseline, the mean LoBC score was higher in the group that became less external (33.81 vs. 24.56), p = 0.006, while this was reverse at follow-up (23.57 vs. 34.41), p = 0.001. Dementia severity and dependence in physical self-maintenance increased during the 12 months in both groups. Among those becoming more external, we also found a decline in cognition (p = 0.002), an increase in dependence in daily activities (p = 0.003), an increase in the use of prescribed medication, and a decrease in depressive symptomatology (p = 0.003). The baseline LoCB score was the only variable associated with 12-month change in LoCB scores (p = 0.001).

Conclusion: Most participants showed a clinically meaningful change in locus of control after 12 months. Those with more signs of dementia progression reported a decrease in personal control but also a decrease in depressive symptoms. These findings are interesting for our understanding of coping but must be replicated with a larger sample.

简介了解个人控制感是如何随着时间的推移而变化的,可以为了解痴呆症患者如何应对痴呆症提供有价值的见解。本研究旨在探讨痴呆症患者的控制感在 12 个月内的变化情况:研究包括 52 名痴呆症患者。控制感是通过行为控制感量表(LoCB)来测量的,得分越高表示外部控制感越强,也就是个人控制感越弱。LoCB上≥5%的变化被认为具有临床意义。我们记录了社会人口学特征,并评估了痴呆症的严重程度、认知能力、独立完成日常活动和身体自我维护的能力、抑郁症状以及处方药的数量。研究分析了12个月后LoCB得分增加(外部因素较多)或减少(外部因素较少)的患者之间的差异,并研究了基线变量与LoCB得分变化之间的关联:总样本的 LoCB 平均分在 12 个月后没有变化(基线平均分 29.33 vs. 随访平均分 30.33,p = 0.553);但出现了两个亚组。使用≥5% 的分界线显示,92.3% 的样本的 LoCB 分数发生了变化,21 名参与者的 LoCB 分数变低,27 名参与者的 LoCB 分数变高。基线时,外在性降低组的平均 LoCB 得分更高(33.81 对 24.56),p = 0.006,而随访时情况相反(23.57 对 34.41),p = 0.001。在这 12 个月中,两组患者的痴呆严重程度和对身体自我维护的依赖程度都有所上升。我们还发现,在变得更加外向的人群中,认知能力下降(p = 0.002),对日常活动的依赖性增加(p = 0.003),处方药使用增加,抑郁症状减轻(p = 0.003)。基线 LoCB 分数是与 12 个月 LoCB 分数变化相关的唯一变量(p = 0.001):结论:12 个月后,大多数参与者的控制感都出现了有临床意义的变化。结论:12 个月后,大多数参与者的控制感都出现了有临床意义的变化,痴呆症进展迹象较多的参与者的个人控制感有所下降,但抑郁症状也有所减轻。这些发现对我们了解应对方法很有意义,但必须在更大样本中进行重复。
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引用次数: 0
Effectiveness and Safety of Aromatherapy in Managing Behavioral and Psychological Symptoms of Dementia: A Mixed-Methods Systematic Review. 芳香疗法治疗痴呆行为和心理症状的有效性和安全性:一项混合方法的系统评价。
IF 2.3 Q2 Medicine Pub Date : 2021-12-02 eCollection Date: 2021-09-01 DOI: 10.1159/000519915
Becky Siu Yin Li, Carmen Wing Han Chan, Minjie Li, Irene Kit Yee Wong, Yvonne Hoi Un Yu

Introduction: Behavioral and psychological symptoms of dementia (BPSD) is the most prominent and distressing manifestation for older persons with dementia (PWD) and caregivers. Aromatherapy has demonstrated its effectiveness in managing BPSD in various studies. However, previous studies and systematic reviews have obtained inconsistent findings, and a review of qualitative studies is yet to be conducted.

Method: A mixed-methods systematic review with a convergent segregated approach was performed to evaluate the effectiveness of aromatherapy in improving the BPSD and quality of life (QoL) of PWD and in relieving the distress and burden of caregivers, as well as its safety for PWD. Both published and unpublished quantitative and qualitative studies written in English and Chinese between January 1996 and December 2020 were retrieved from 28 databases, including MEDLINE, EMBASE, and Web of Science, based on the prespecified criteria. The methodological quality was assessed by using critical appraisal tools from the Joanna Briggs Institute. Quantitative synthesis, qualitative synthesis, and integration of quantitative and qualitative evidence were performed.

Results: A total of 12 randomized controlled trials, 10 quasi-experimental studies, and 2 qualitative studies were included in the review. Some inconsistent findings regarding the effectiveness of aromatherapy in reducing the severity of BPSD were observed. Some studies reported that aromatherapy significantly improved the QoL of PWD and relieved the distress and burden of caregivers, promoted a positive experience among caregivers, and had very low adverse effects on PWD (with aromatherapy inhalation reporting no adverse effects).

Conclusion: Aromatherapy, especially in the inhalation approach, could be a potentially safe and effective strategy for managing BPSD. However, more structuralized and comparable studies with sufficient sample size, adherence monitoring, and sound theoretical basis could be conducted to obtain conclusive findings.

引言:痴呆症(BPSD)的行为和心理症状是老年痴呆症(PWD)患者和护理人员最突出和最痛苦的表现。芳香疗法已在各种研究中证明其在管理BPSD方面的有效性。然而,先前的研究和系统综述获得了不一致的结果,定性研究的综述尚待进行。方法:采用融合-分离的混合方法进行系统评价,以评估芳香疗法在改善PWD的BPSD和生活质量(QoL)、减轻护理人员的痛苦和负担方面的有效性及其对PWD的安全性。根据预先指定的标准,从MEDLINE、EMBASE和Web of Science等28个数据库中检索1996年1月至2020年12月期间已发表和未发表的中英文定量和定性研究。方法学质量是通过使用乔安娜·布里格斯研究所的关键评估工具进行评估的。进行了定量合成、定性合成以及定量和定性证据的整合。结果:共纳入12项随机对照试验、10项准实验研究和2项定性研究。关于芳香疗法在降低BPSD严重程度方面的有效性,观察到了一些不一致的发现。一些研究报告称,芳香疗法显著改善了PWD的生活质量,减轻了照顾者的痛苦和负担,促进了照顾者之间的积极体验,并且对PWD的不良反应非常低(吸入芳香疗法报告没有不良反应),这可能是一种潜在的安全有效的BPSD管理策略。然而,可以进行更结构化和可比较的研究,具有足够的样本量、依从性监测和完善的理论基础,以获得结论性的发现。
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引用次数: 4
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Dementia and Geriatric Cognitive Disorders Extra
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