Laura Plata-Casas, Oscar Gutiérrez-Lesmes, Favio Cala-Vitery
Objective: to estimate disability-adjusted life years in women attributable to tuberculosis in Colombia 2010-2018. Methods: A retrospective descriptive study was conducted. The following variables were studied: year of occurrence, age groups and origin. This study included 41,354 women who consulted in the hospital network and 2530 cases of mortality in women, registered in the country’s vital statistics system. Using the abbrevia¬ted methodology proposed by the World Health Organization for measuring the burden of disease BD, years of life lost, years of life with disability and years of healthy life lost by women at the subnational level were estimated. Results: The Disability-Adjusted Life Years rate for the study period was 427.2 (95% II 353-492.3) per 100,000 women. Women of reproductive age (10 to 49 years old) account for 57.9 per cent of these. Departments such as Amazonas 1,426 (725.4-2,541.4) and Guajira 1,001.1 (693.3-1,260) had the highest rates (per 100,000 inhabitants). Twelve territorial entities have an increasing burden of disease. Conclusions: The rate of disability-adjusted life years due to tuberculosis in women for nine years was high and presents subnational differences perhaps due to large social or economic gaps or deficits in institutional or programmatic capacities.
目的:估计2010-2018年哥伦比亚妇女因结核病导致的残疾调整生命年。方法:采用回顾性描述性研究。研究了以下变量:发病年份、年龄组和发病来源。这项研究包括在医院网络咨询的41354名妇女和在国家生命统计系统中登记的2530例妇女死亡病例。使用世界卫生组织提出的用于衡量双相障碍疾病负担的简化方法，估计了国家以下一级妇女损失的寿命年数、残疾寿命年数和健康寿命年数。结果:研究期间的残疾调整生命年率为每10万名妇女427.2 (95% II 353-492.3)。其中育龄妇女(10至49岁)占57.9%。亚马逊省1426人(725.4- 2541.4人)和瓜希拉省1001.1人(693.3- 1260人)的犯罪率最高(每10万居民)。12个领土实体的疾病负担日益加重。结论:9年妇女因结核病导致的残疾调整生命年率很高，并且可能由于社会或经济差距较大或机构或规划能力不足而存在国家以下差异。
{"title":"The burden of tuberculosis disease in women, Colombia 2010-2018","authors":"Laura Plata-Casas, Oscar Gutiérrez-Lesmes, Favio Cala-Vitery","doi":"10.22354/24223794.1141","DOIUrl":"https://doi.org/10.22354/24223794.1141","url":null,"abstract":"Objective: to estimate disability-adjusted life years in women attributable to tuberculosis in Colombia 2010-2018. Methods: A retrospective descriptive study was conducted. The following variables were studied: year of occurrence, age groups and origin. This study included 41,354 women who consulted in the hospital network and 2530 cases of mortality in women, registered in the country’s vital statistics system. Using the abbrevia¬ted methodology proposed by the World Health Organization for measuring the burden of disease BD, years of life lost, years of life with disability and years of healthy life lost by women at the subnational level were estimated. Results: The Disability-Adjusted Life Years rate for the study period was 427.2 (95% II 353-492.3) per 100,000 women. Women of reproductive age (10 to 49 years old) account for 57.9 per cent of these. Departments such as Amazonas 1,426 (725.4-2,541.4) and Guajira 1,001.1 (693.3-1,260) had the highest rates (per 100,000 inhabitants). Twelve territorial entities have an increasing burden of disease. Conclusions: The rate of disability-adjusted life years due to tuberculosis in women for nine years was high and presents subnational differences perhaps due to large social or economic gaps or deficits in institutional or programmatic capacities.","PeriodicalId":38132,"journal":{"name":"Infectio","volume":"44 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135205803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
El síndrome hemofagocítico secundario a mucormicosis en pacientes inmunocomptetentes es raro. La combinación de ambas entidades ocasiona alta mortalidad a pesar de esfuerzos médicos y quirúrgicos. La terapia antifúngica recomendada es la anfotericina B a altas dosis unida a un azol. Se recomienda medir sensibilidad del hongo para los diferentes anti fúngicos.
{"title":"Síndrome hemofagocítico por mucormicosis en paciente pediátrico inmunocompetente. Reporte de caso","authors":"Gloria Celeste Samudio-Domínguez, Rolando Giménez, Natalia Ortega, Tamara Martínez, Gustavo Aguilar, Lorena Quintero, Luis Fabián Celias","doi":"10.22354/24223794.1143","DOIUrl":"https://doi.org/10.22354/24223794.1143","url":null,"abstract":"El síndrome hemofagocítico secundario a mucormicosis en pacientes inmunocomptetentes es raro. La combinación de ambas entidades ocasiona alta mortalidad a pesar de esfuerzos médicos y quirúrgicos. La terapia antifúngica recomendada es la anfotericina B a altas dosis unida a un azol. Se recomienda medir sensibilidad del hongo para los diferentes anti fúngicos.","PeriodicalId":38132,"journal":{"name":"Infectio","volume":"49 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135205805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Diana Marcela Hoyos-Llanos, Nicolas Andres Cortes-Mejia, Daniela Lucia Rico-Bolivar, Paula Giraldo-Posada, Francisco Alexander Perez-Rengifo, Alonso Vera-Torres
Guillain-Barré syndrome (GBS) is an immune-mediated condition affecting both the motor and sensory spinal roots and peripheric nerves. GBS is a rare entity, with its global incidence being as low as 0.81 to 1.89 cases per 100.000 person-year. Despite its low incidence, GBS have an important morbidity and lethal potential. This syndrome is usually triggered by infections. Due to its clinical presentation heterogeneity and its disease natural history, there is scarse availability of international clinical practice guidelines for the management of this entity. In this report, we present the case of a 67 years-old man on his fifth month after liver transplant (LT), who developed acute non-inflammatory diarrhea followed by sudden ascending symmetric paresia and soles paresthesias. Electrophysiologic studies reported a demyelinating inflammatory polyradiculoneuropathy compatible with GBS, acute severe inflammatory demyelinating polyneuropathy (AIDP) subtype. His neurolo¬gy deficit was associated with a simultaneous primary Cytomegalovirus (CMV) infection, one of the most common GBS-related infectious agents.
{"title":"Cytomegalovirus-related Guillain-Barre syndrome in an adult liver transplant recipient: a case report","authors":"Diana Marcela Hoyos-Llanos, Nicolas Andres Cortes-Mejia, Daniela Lucia Rico-Bolivar, Paula Giraldo-Posada, Francisco Alexander Perez-Rengifo, Alonso Vera-Torres","doi":"10.22354/24223794.1144","DOIUrl":"https://doi.org/10.22354/24223794.1144","url":null,"abstract":"Guillain-Barré syndrome (GBS) is an immune-mediated condition affecting both the motor and sensory spinal roots and peripheric nerves. GBS is a rare entity, with its global incidence being as low as 0.81 to 1.89 cases per 100.000 person-year. Despite its low incidence, GBS have an important morbidity and lethal potential. This syndrome is usually triggered by infections. Due to its clinical presentation heterogeneity and its disease natural history, there is scarse availability of international clinical practice guidelines for the management of this entity. In this report, we present the case of a 67 years-old man on his fifth month after liver transplant (LT), who developed acute non-inflammatory diarrhea followed by sudden ascending symmetric paresia and soles paresthesias. Electrophysiologic studies reported a demyelinating inflammatory polyradiculoneuropathy compatible with GBS, acute severe inflammatory demyelinating polyneuropathy (AIDP) subtype. His neurolo¬gy deficit was associated with a simultaneous primary Cytomegalovirus (CMV) infection, one of the most common GBS-related infectious agents.","PeriodicalId":38132,"journal":{"name":"Infectio","volume":"330 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135205808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Luis Álvaro Melo-Burbano, Duván Arley Galindes-Casanova, Edith Norela Benitez-Escobar, Jorge Karim Assis-Reveiz, Jorge Enrique Daza-Arana, José Millán Oñate-Gutiérrez
Objetivo: Determinar la frecuencia del uso de antibióticos y conocer qué variables clínicas y socio-demográficas se relacionaban con la probabilidad de sufrir infecciones asociadas a COVID-19. Métodos: Se evaluaron adultos hospitalizados por COVID-19 quienes recibieron uno o más antibióticos durante su internación. Se realizó un análisis descriptivo de las variables en la población general‚ análisis bivariado en dos grupos (infección documentada vs infección presunta) y regresión logística multivariada de factores asociados a mortalidad. Resultados: Se determinó que el 60,4% de los adultos hospitalizados por COVID-19, recibieron antibióticos. Se documentó coinfección en el 6,2% y sobreinfección en el 23,3%. El 75,8% de los cultivos reportaron gérmenes gramnegativos, 17,8% hongos y 14,2% grampositivos. Variables como edad, comorbilidades, UCI, anemia, esteroides, ventilación mecánica, hemofiltración se relacionaron de forma estadísticamente significativa con infección documentada. La cánula de alto flujo se asoció como factor protector. La mortalidad en general fue del 43.9%, 57.8% en el primer grupo y 38.1% en el segundo (p=0.002). Conclusión: Existe una frecuencia considerable del uso de antibióticos en sujetos hospitalizados por COVID-19, particularmente relacionada con hallazgos relevantes de sobreinfección bacteriana, en aquellos con comorbilidades, como la diabetes mellitus, estados de inmunosupresión, anemia y fragilidad, en quienes el comportamiento de la enfermedad cursa con mayor severidad y letalidad.
{"title":"Frecuencia de prescripción de antibióticos en adultos hospitalizados por SARS-CoV-2 en una institución de alta complejidad en Santiago de Cali, Colombia","authors":"Luis Álvaro Melo-Burbano, Duván Arley Galindes-Casanova, Edith Norela Benitez-Escobar, Jorge Karim Assis-Reveiz, Jorge Enrique Daza-Arana, José Millán Oñate-Gutiérrez","doi":"10.22354/24223794.1128","DOIUrl":"https://doi.org/10.22354/24223794.1128","url":null,"abstract":"Objetivo: Determinar la frecuencia del uso de antibióticos y conocer qué variables clínicas y socio-demográficas se relacionaban con la probabilidad de sufrir infecciones asociadas a COVID-19. Métodos: Se evaluaron adultos hospitalizados por COVID-19 quienes recibieron uno o más antibióticos durante su internación. Se realizó un análisis descriptivo de las variables en la población general‚ análisis bivariado en dos grupos (infección documentada vs infección presunta) y regresión logística multivariada de factores asociados a mortalidad. Resultados: Se determinó que el 60,4% de los adultos hospitalizados por COVID-19, recibieron antibióticos. Se documentó coinfección en el 6,2% y sobreinfección en el 23,3%. El 75,8% de los cultivos reportaron gérmenes gramnegativos, 17,8% hongos y 14,2% grampositivos. Variables como edad, comorbilidades, UCI, anemia, esteroides, ventilación mecánica, hemofiltración se relacionaron de forma estadísticamente significativa con infección documentada. La cánula de alto flujo se asoció como factor protector. La mortalidad en general fue del 43.9%, 57.8% en el primer grupo y 38.1% en el segundo (p=0.002). Conclusión: Existe una frecuencia considerable del uso de antibióticos en sujetos hospitalizados por COVID-19, particularmente relacionada con hallazgos relevantes de sobreinfección bacteriana, en aquellos con comorbilidades, como la diabetes mellitus, estados de inmunosupresión, anemia y fragilidad, en quienes el comportamiento de la enfermedad cursa con mayor severidad y letalidad.","PeriodicalId":38132,"journal":{"name":"Infectio","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46523563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sara Tellez-Carrasquilla, Erika A. Rodríguez, J. N. Jiménez
Introducción: La resistencia bacteriana es una problemática multifactorial, donde otros escenarios diferentes al hospitalario han cobrado gran importancia. Objetivo: Determinar la presencia de bacilos Gram negativos resistentes a betalactámicos de importancia clínica en aguas residuales de un hospital de alta complejidad de la ciudad de Medellín, Antioquia. Materiales y métodos: Estudio descriptivo de corte transversal. Entre noviembre y diciembre de 2018 se realizaron dos muestreos en dos efluentes de agua residual de un hospital de alta complejidad. Las bacterias fueron aisladas empleando medios cromogénicos y posteriormente se realizó caracterización molecular de betalactamasas empleando PCR. La identificación bacteriana y la susceptibilidad se llevaron a cabo por métodos automatizados. Resultados: Noventa aislados fueron obtenidos, de los cuales el 78,90% (n=71) portaban al menos un gen que codificaba para BLEE ó penicilinasas; y el 78,90% (n=71) al menos un gen para carbapenemasas. Citrobacter freundii fue la bacteria predominante (30% n=12), seguida de Klebsiella pneumoniae (25% n=10). En todos los aislados seleccionados se encontró Multidrogorresistencia (MDR) (100% n=40). Conclusión: La alta presencia de bacterias resistentes a betalactámicos en aguas residuales hospitalarias evidencia la necesidad de implementar estrategias de manejo de estos desechos, dado el riesgo potencial para la transmisión y diseminación de bacterias resistentes.
{"title":"Alta frecuencia de bacilos Gram negativos de importancia clínica resistentes a betalactámicos en efluentes de aguas residuales hospitalarias","authors":"Sara Tellez-Carrasquilla, Erika A. Rodríguez, J. N. Jiménez","doi":"10.22354/24223794.1126","DOIUrl":"https://doi.org/10.22354/24223794.1126","url":null,"abstract":"Introducción: La resistencia bacteriana es una problemática multifactorial, donde otros escenarios diferentes al hospitalario han cobrado gran importancia. Objetivo: Determinar la presencia de bacilos Gram negativos resistentes a betalactámicos de importancia clínica en aguas residuales de un hospital de alta complejidad de la ciudad de Medellín, Antioquia. Materiales y métodos: Estudio descriptivo de corte transversal. Entre noviembre y diciembre de 2018 se realizaron dos muestreos en dos efluentes de agua residual de un hospital de alta complejidad. Las bacterias fueron aisladas empleando medios cromogénicos y posteriormente se realizó caracterización molecular de betalactamasas empleando PCR. La identificación bacteriana y la susceptibilidad se llevaron a cabo por métodos automatizados. Resultados: Noventa aislados fueron obtenidos, de los cuales el 78,90% (n=71) portaban al menos un gen que codificaba para BLEE ó penicilinasas; y el 78,90% (n=71) al menos un gen para carbapenemasas. Citrobacter freundii fue la bacteria predominante (30% n=12), seguida de Klebsiella pneumoniae (25% n=10). En todos los aislados seleccionados se encontró Multidrogorresistencia (MDR) (100% n=40). Conclusión: La alta presencia de bacterias resistentes a betalactámicos en aguas residuales hospitalarias evidencia la necesidad de implementar estrategias de manejo de estos desechos, dado el riesgo potencial para la transmisión y diseminación de bacterias resistentes.","PeriodicalId":38132,"journal":{"name":"Infectio","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48721789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nurcan Duman, R. C. Sarınoğlu, Beyza Nur Kuzan, Mehmet Mucahit Güncü, Bülent Aslan, Nuri Çagatay Cimşit, A. Karahasan
We aimed to analyze the distribution of respiratory pathogens(RP) detected by a multiplex PCR-based method (BioFire Diagnostics, USA) among patients with suspected respiratory tract infections (RTI) and to evaluate the demographic, clinical and radiological characteristics of infected individuals . RP were detected in 1621/6376 (25.4%) of the samples in the years 2018-2020. Rhinovirus/enterovirus (RV/EV) were the most commonly detected pathogens (38.1%) followed by influenza A and B viruses (21%) and parainfluenza virus (PIV) (9.5%). Single pathogen was detected in 1361 (84%) and multi pathogens in 260 (16%) of 1621 samples. At least one comorbidity was present in 379 (30.5%) of the patients. Fever was the most common sign followed by cough and dyspnea. Thorax CT was present in 426 of 1243 RP positive patients (34.3%). Any radiological findings was found significantly related for a specific pathogen. No medication was given to 52.9% whereas antibiotics in 35.7% and antivirals in 3.8% of the patients. Film Array panel as a multiplex PCR test is not used rationally in our hospital and results were not dramatically improve management of RTI. A better communication between clinician and microbiologist is required for efficient use of laboratory and rational use of antimicrobials.
{"title":"Evaluation of BioFire Filmarray panel for respiratory pathogens: a demographic and clinical analysis in Istanbul, Turkey","authors":"Nurcan Duman, R. C. Sarınoğlu, Beyza Nur Kuzan, Mehmet Mucahit Güncü, Bülent Aslan, Nuri Çagatay Cimşit, A. Karahasan","doi":"10.22354/24223794.1127","DOIUrl":"https://doi.org/10.22354/24223794.1127","url":null,"abstract":"We aimed to analyze the distribution of respiratory pathogens(RP) detected by a multiplex PCR-based method (BioFire Diagnostics, USA) among patients with suspected respiratory tract infections (RTI) and to evaluate the demographic, clinical and radiological characteristics of infected individuals . RP were detected in 1621/6376 (25.4%) of the samples in the years 2018-2020. Rhinovirus/enterovirus (RV/EV) were the most commonly detected pathogens (38.1%) followed by influenza A and B viruses (21%) and parainfluenza virus (PIV) (9.5%). Single pathogen was detected in 1361 (84%) and multi pathogens in 260 (16%) of 1621 samples. At least one comorbidity was present in 379 (30.5%) of the patients. Fever was the most common sign followed by cough and dyspnea. Thorax CT was present in 426 of 1243 RP positive patients (34.3%). Any radiological findings was found significantly related for a specific pathogen. No medication was given to 52.9% whereas antibiotics in 35.7% and antivirals in 3.8% of the patients. Film Array panel as a multiplex PCR test is not used rationally in our hospital and results were not dramatically improve management of RTI. A better communication between clinician and microbiologist is required for efficient use of laboratory and rational use of antimicrobials.","PeriodicalId":38132,"journal":{"name":"Infectio","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44138480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Iván Felipe Gutiérrez-Tobar, María Alejandra Palacios-Ariza, Diego Andrés Luna-Solarte, William Hernando Niño-Uribe, Angie Catalina González-Garzón, S. J. Beltrán-Higuera, Liliana Barrero-Garzón, María Valeria Muñoz-Gutiérrez, María Paula Alba-Bernal, Kelly Márquez-Herrera, Vanessa Medina-Gaviria, Martín Alonso La Rotta-Diaz, Nubia Constanza Ponce-Zapata, Mónica Paola Novoa-Candia, Jhon Camacho-Cruz, Camilo Enrique Rincón-Millán, Ana María Rubiano-Acevedo, Angélica Agudelo-Quintero, Germán Enrique Galvis-Ruiz, Camilo Alberto Caicedo-Montaño, Nancy Yomayusa-González, C. Álvarez-Moreno
En el año 2019 se publicó la guía de práctica clínica para el diagnóstico y manejo de las infecciones de piel y tejidos blandos en Colombia. Dicha guía excluía a la población pediátrica por sus consideraciones especiales. Teniendo en cuenta que estas infecciones representan un motivo de consulta frecuente en pediatría y que la emergencia del Staphylococcus aureus resistente a meticilina generan la necesidad de actualizar conocimientos y estrategias para el manejo de las infecciones de piel y tejidos blandos superficiales, se presenta esta guía de práctica clínica que da respuesta basada en la evidencia a 12 preguntas. Dicha evidencia fue adaptada y graduada bajo el sistema GRADE posterior a un proceso de adaptación de tres guías publicadas. Adicionalmente, se realizó una actualización de la evidencia científica bajo una búsqueda sistemática. Por último, se realizó un consenso de expertos para la evaluación de las potenciales barreras para la implementación de las recomendaciones en el contexto local.
{"title":"Guía de práctica clínica colombiana para el tratamiento de infecciones bacterianas de piel y tejidos blandos superficiales en Población pediátrica","authors":"Iván Felipe Gutiérrez-Tobar, María Alejandra Palacios-Ariza, Diego Andrés Luna-Solarte, William Hernando Niño-Uribe, Angie Catalina González-Garzón, S. J. Beltrán-Higuera, Liliana Barrero-Garzón, María Valeria Muñoz-Gutiérrez, María Paula Alba-Bernal, Kelly Márquez-Herrera, Vanessa Medina-Gaviria, Martín Alonso La Rotta-Diaz, Nubia Constanza Ponce-Zapata, Mónica Paola Novoa-Candia, Jhon Camacho-Cruz, Camilo Enrique Rincón-Millán, Ana María Rubiano-Acevedo, Angélica Agudelo-Quintero, Germán Enrique Galvis-Ruiz, Camilo Alberto Caicedo-Montaño, Nancy Yomayusa-González, C. Álvarez-Moreno","doi":"10.22354/24223794.1131","DOIUrl":"https://doi.org/10.22354/24223794.1131","url":null,"abstract":"En el año 2019 se publicó la guía de práctica clínica para el diagnóstico y manejo de las infecciones de piel y tejidos blandos en Colombia. Dicha guía excluía a la población pediátrica por sus consideraciones especiales. Teniendo en cuenta que estas infecciones representan un motivo de consulta frecuente en pediatría y que la emergencia del Staphylococcus aureus resistente a meticilina generan la necesidad de actualizar conocimientos y estrategias para el manejo de las infecciones de piel y tejidos blandos superficiales, se presenta esta guía de práctica clínica que da respuesta basada en la evidencia a 12 preguntas. Dicha evidencia fue adaptada y graduada bajo el sistema GRADE posterior a un proceso de adaptación de tres guías publicadas. Adicionalmente, se realizó una actualización de la evidencia científica bajo una búsqueda sistemática. Por último, se realizó un consenso de expertos para la evaluación de las potenciales barreras para la implementación de las recomendaciones en el contexto local.","PeriodicalId":38132,"journal":{"name":"Infectio","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48441401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Luis Guillermo Toro-Rendón, D. Rojas-Gualdrón, Ferney Alexander Rodriguez-Tobon, Carlos Andres Perez-Urrego, U. Palacios-Barahona
Objective: To estimate the direct costs of hospital care according to coinfection in adult COVID-19 patients. Materials and methods: A retrospective follow-up study of adult patients hospitalized for COVID-19 between March and August 2020 at the San Vicente Foundation Hospitals (Medellín and Rionegro, Colombia). Patients whose diagnosis of SARS-Cov2 pneumonia was confirmed by RT-PCR test were included. Death from any cause and length of stay were considered outcome variables. Costs were estimated in 20 20 US dollars. Results: 365 patients with an average age of 60 years (IQR: 46-71), 40% female, were analyzed. 60.5% required an Intensive Care Unit (ICU). All-cause mortality was 2.87 per 100 patient-days. Patients admitted to the ICU who developed coinfection had an average length of stay of 27.8 days (SD:17.1) and an average cost of $23,935.7 (SD: $16,808.2); patients admitted to the ICU who did not develop a coinfection had an average length of stay of 14.7 days (SD:8.6) and an average cost of $9,968.5 (SD: $8,054.0). Conclusion: A high percentage of patients required intensive care, and there was a high mortality due to COVID-19. In addition, a higher cost of care was observed for those patients who developed coinfection and were admitted to ICU.
{"title":"Direct costs of hospital care according to coinfection in adult COVID-19 patients","authors":"Luis Guillermo Toro-Rendón, D. Rojas-Gualdrón, Ferney Alexander Rodriguez-Tobon, Carlos Andres Perez-Urrego, U. Palacios-Barahona","doi":"10.22354/24223794.1125","DOIUrl":"https://doi.org/10.22354/24223794.1125","url":null,"abstract":"Objective: To estimate the direct costs of hospital care according to coinfection in adult COVID-19 patients. Materials and methods: A retrospective follow-up study of adult patients hospitalized for COVID-19 between March and August 2020 at the San Vicente Foundation Hospitals (Medellín and Rionegro, Colombia). Patients whose diagnosis of SARS-Cov2 pneumonia was confirmed by RT-PCR test were included. Death from any cause and length of stay were considered outcome variables. Costs were estimated in 20 20 US dollars. Results: 365 patients with an average age of 60 years (IQR: 46-71), 40% female, were analyzed. 60.5% required an Intensive Care Unit (ICU). All-cause mortality was 2.87 per 100 patient-days. Patients admitted to the ICU who developed coinfection had an average length of stay of 27.8 days (SD:17.1) and an average cost of $23,935.7 (SD: $16,808.2); patients admitted to the ICU who did not develop a coinfection had an average length of stay of 14.7 days (SD:8.6) and an average cost of $9,968.5 (SD: $8,054.0). Conclusion: A high percentage of patients required intensive care, and there was a high mortality due to COVID-19. In addition, a higher cost of care was observed for those patients who developed coinfection and were admitted to ICU.","PeriodicalId":38132,"journal":{"name":"Infectio","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46313349","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Neglected tropic diseases: a reflexion in times of pandemic about how to intervene under the optics of one health","authors":"Wilmer E. Villamil –Gomez","doi":"10.22354/24223794.1124","DOIUrl":"https://doi.org/10.22354/24223794.1124","url":null,"abstract":"","PeriodicalId":38132,"journal":{"name":"Infectio","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48145852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sebastián Hernández-Garzón, Samuel Martinez-Vernaza, Raúl Delgado-Marrugo, Juan Sebastian Montealegre-Diaz
El trauma abierto es una de las principales urgencias que se presentan en el servicio de Ortopedia y trauma. Dentro de este campo y cuando hay progresión a infección, usualmente existe un grupo de microorganismos a tener en cuenta de acuerdo con la epidemiología local; sin embargo, la presencia de material vegetal, común en agricultores y militares, orienta a considerar microorganismos diferentes. Dentro de ellos se encuentra Pantoea spp causante comúnmente de artritis séptica, pero, sin relación clara con osteomielitis y/o infección periprotésica, más comúnmente se ha documentado por este microorganismo endocarditis infecciosa, sepsis asociada a catéter y neumonía asociada a ventilador, entre otras. A continuación, se presenta el caso de un paciente de 21 años de edad con antecedente de osteosíntesis en radio y cúbito del antebrazo derecho, quien después de una fractura abierta se aisla este microorganismo y requiere de terapia dirigida, se presenta su diagnóstico y evolución.
{"title":"Osteomielitis por Pantoea spp en paciente no inmunosuprimido asociado a trauma: reporte de caso y revisión de la literatura","authors":"Sebastián Hernández-Garzón, Samuel Martinez-Vernaza, Raúl Delgado-Marrugo, Juan Sebastian Montealegre-Diaz","doi":"10.22354/24223794.1133","DOIUrl":"https://doi.org/10.22354/24223794.1133","url":null,"abstract":"El trauma abierto es una de las principales urgencias que se presentan en el servicio de Ortopedia y trauma. Dentro de este campo y cuando hay progresión a infección, usualmente existe un grupo de microorganismos a tener en cuenta de acuerdo con la epidemiología local; sin embargo, la presencia de material vegetal, común en agricultores y militares, orienta a considerar microorganismos diferentes. Dentro de ellos se encuentra Pantoea spp causante comúnmente de artritis séptica, pero, sin relación clara con osteomielitis y/o infección periprotésica, más comúnmente se ha documentado por este microorganismo endocarditis infecciosa, sepsis asociada a catéter y neumonía asociada a ventilador, entre otras. A continuación, se presenta el caso de un paciente de 21 años de edad con antecedente de osteosíntesis en radio y cúbito del antebrazo derecho, quien después de una fractura abierta se aisla este microorganismo y requiere de terapia dirigida, se presenta su diagnóstico y evolución.","PeriodicalId":38132,"journal":{"name":"Infectio","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43399468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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