Pub Date : 2021-07-03DOI: 10.47316/cajmhe.2021.2.2.02
M. Gromova, V. Tsurko, A. S. Melekhina
Patients with gout are advised to follow a certain diet. The search for healthy eating habits continues. This overview aims to explore the impact of the Central Asian diet on the development and course of hyperuricemia and gout and to propose related preventive measures. We processed English articles reflecting on the impact of the Central Asian diet on the development of gout and the frequency of gout attacks. Central Asian dishes such as lagman, pilaf, and manty are distinguished for high nutritional value and abundance of saturated fats, red meat, and trans fats. Moderate consumption of Central Asian traditional dishes is advisable to prevent weight gain and gout attacks. Patients with gout are additionally encouraged to consume low-calorie and non-fat products and regularly intake fruits and vegetables during meals. Patients with gout should be provided with information about a healthy diet and lifestyle. More evidence-based studies are warranted to provide better quality guidance on gout prevention and treatment.
{"title":"GOUT AND THE CENTRAL ASIAN DIET","authors":"M. Gromova, V. Tsurko, A. S. Melekhina","doi":"10.47316/cajmhe.2021.2.2.02","DOIUrl":"https://doi.org/10.47316/cajmhe.2021.2.2.02","url":null,"abstract":"Patients with gout are advised to follow a certain diet. The search for healthy eating habits continues. This overview aims to explore the impact of the Central Asian diet on the development and course of hyperuricemia and gout and to propose related preventive measures. We processed English articles reflecting on the impact of the Central Asian diet on the development of gout and the frequency of gout attacks. Central Asian dishes such as lagman, pilaf, and manty are distinguished for high nutritional value and abundance of saturated fats, red meat, and trans fats. Moderate consumption of Central Asian traditional dishes is advisable to prevent weight gain and gout attacks. Patients with gout are additionally encouraged to consume low-calorie and non-fat products and regularly intake fruits and vegetables during meals. Patients with gout should be provided with information about a healthy diet and lifestyle. More evidence-based studies are warranted to provide better quality guidance on gout prevention and treatment.","PeriodicalId":388483,"journal":{"name":"Central Asian Journal of Medical Hypotheses and Ethics","volume":"21 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126884465","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-07-03DOI: 10.47316/cajmhe.2021.2.2.01
Burhan Fatih Koçyiğit, Ahmet Akyol
The quality and impact of scholarly articles are traditionally evaluated using metrics that put citation counts at the center. In the era of digitization, advanced online platforms and social media have transformed the dissemination of scientific information results and introduced new metrics for evaluating the influence of scholarly outputs and planning research studies. Alternative metrics (altmetrics) have emerged as tools for immediate measuring of scholarly outputs upon their online publication and dissemination through numerous online platforms, including social media channels. The Altmetrtic Attention Score by Altmetric.com has gained its global importance as an integral indicator for evaluation of constantly changing societal influence of individual articles. To a large extent, this and other social media metrics complement established citation metrics, allowing to visualize and predict implications at early stages of post-publication promotion. This article overviews characterstics of various altmetric tools and their growing roles for planning and evaluating scientific research.
{"title":"ALTMETRICS AND CITATION METRICS AS COMPLEMENTARY INDICATORS FOR RESEARCH MANAGEMENT","authors":"Burhan Fatih Koçyiğit, Ahmet Akyol","doi":"10.47316/cajmhe.2021.2.2.01","DOIUrl":"https://doi.org/10.47316/cajmhe.2021.2.2.01","url":null,"abstract":"The quality and impact of scholarly articles are traditionally evaluated using metrics that put citation counts at the center. In the era of digitization, advanced online platforms and social media have transformed the dissemination of scientific information results and introduced new metrics for evaluating the influence of scholarly outputs and planning research studies. Alternative metrics (altmetrics) have emerged as tools for immediate measuring of scholarly outputs upon their online publication and dissemination through numerous online platforms, including social media channels. The Altmetrtic Attention Score by Altmetric.com has gained its global importance as an integral indicator for evaluation of constantly changing societal influence of individual articles. To a large extent, this and other social media metrics complement established citation metrics, allowing to visualize and predict implications at early stages of post-publication promotion. This article overviews characterstics of various altmetric tools and their growing roles for planning and evaluating scientific research.","PeriodicalId":388483,"journal":{"name":"Central Asian Journal of Medical Hypotheses and Ethics","volume":"60 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131586590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-07-03DOI: 10.47316/CAJMHE.2021.2.2.08
S. Ahmed
BLACK AND WHITE; GREEN, GOLD AND PLATINUM: THE COLOURS OF PUBLISHING!
黑白相间;绿色、金色和铂金:出版的颜色!
{"title":"BLACK AND WHITE; GREEN, GOLD AND PLATINUM: THE COLOURS OF PUBLISHING!","authors":"S. Ahmed","doi":"10.47316/CAJMHE.2021.2.2.08","DOIUrl":"https://doi.org/10.47316/CAJMHE.2021.2.2.08","url":null,"abstract":"BLACK AND WHITE; GREEN, GOLD AND PLATINUM: THE COLOURS OF PUBLISHING!","PeriodicalId":388483,"journal":{"name":"Central Asian Journal of Medical Hypotheses and Ethics","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131982629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-07-03DOI: 10.47316/cajmhe.2021.2.2.09
A. Sakir
MY LIFE AS A RESEARCHER AND EDITOR
我的研究和编辑生涯
{"title":"MY LIFE AS A RESEARCHER AND EDITOR","authors":"A. Sakir","doi":"10.47316/cajmhe.2021.2.2.09","DOIUrl":"https://doi.org/10.47316/cajmhe.2021.2.2.09","url":null,"abstract":"MY LIFE AS A RESEARCHER AND EDITOR","PeriodicalId":388483,"journal":{"name":"Central Asian Journal of Medical Hypotheses and Ethics","volume":"72 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126360333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-07-03DOI: 10.47316/cajmhe.2021.2.2.07
I. Karahan, G. Sengul Aycicek
HOME-BASED PALLIATIVE CARE VIA SMARTPHONE APPLICATIONS DURING THE PANDEMIC
大流行期间通过智能手机应用进行的家庭姑息治疗
{"title":"HOME-BASED PALLIATIVE CARE VIA SMARTPHONE APPLICATIONS DURING THE PANDEMIC","authors":"I. Karahan, G. Sengul Aycicek","doi":"10.47316/cajmhe.2021.2.2.07","DOIUrl":"https://doi.org/10.47316/cajmhe.2021.2.2.07","url":null,"abstract":"HOME-BASED PALLIATIVE CARE VIA SMARTPHONE APPLICATIONS DURING THE PANDEMIC","PeriodicalId":388483,"journal":{"name":"Central Asian Journal of Medical Hypotheses and Ethics","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117295821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-04-02DOI: 10.47316/CAJMHE.2021.2.1.10
D. Misra
MY LIFE AS A RESEARCHER AND EDITOR
我的研究和编辑生涯
{"title":"MY LIFE AS A RESEARCHER AND EDITOR","authors":"D. Misra","doi":"10.47316/CAJMHE.2021.2.1.10","DOIUrl":"https://doi.org/10.47316/CAJMHE.2021.2.1.10","url":null,"abstract":"MY LIFE AS A RESEARCHER AND EDITOR","PeriodicalId":388483,"journal":{"name":"Central Asian Journal of Medical Hypotheses and Ethics","volume":"216 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121727494","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-04-02DOI: 10.47316/CAJMHE.2021.2.1.05
T. Velikova
The course of COVID-19 depends on a dynamic interplay between SARS-CoV-2 and the host's immune system. Although it is an emerging global health issue, little is known about the specificity, safety, and duration of the immunity elicited by the virus. This hypothesis article explores the benefits of infection-acquired and vaccine-induced immunity against COVID-19, suggesting that the latter outweighs the former. Comparative studies are proposed to explain and reveal all aspects of the immune responses. Although vaccine development relies on studies of naturally acquired immune responses, there are still no comparative analyses of the natural and vaccine immunity against SARS-CoV-2. Moreover, there are scarce reports on the characteristics of both types of responses. The scientific facts about the virulence of SARS-CoV-2 affecting the immune system are of great importance for proposed comparative analyses. Various immunological methods can be employed to elucidate infection-acquired and vaccine-induced immunity against SARS-CoV-2. The safe vaccination of subjects with and without COVID-19 history may disrupt the virus spreading and end the pandemic.
{"title":"INFECTION-ACQUIRED VERSUS VACCINE-INDUCED IMMUNITY AGAINST COVID-19","authors":"T. Velikova","doi":"10.47316/CAJMHE.2021.2.1.05","DOIUrl":"https://doi.org/10.47316/CAJMHE.2021.2.1.05","url":null,"abstract":"The course of COVID-19 depends on a dynamic interplay between SARS-CoV-2 and the host's immune system. Although it is an emerging global health issue, little is known about the specificity, safety, and duration of the immunity elicited by the virus. This hypothesis article explores the benefits of infection-acquired and vaccine-induced immunity against COVID-19, suggesting that the latter outweighs the former. Comparative studies are proposed to explain and reveal all aspects of the immune responses. Although vaccine development relies on studies of naturally acquired immune responses, there are still no comparative analyses of the natural and vaccine immunity against SARS-CoV-2. Moreover, there are scarce reports on the characteristics of both types of responses. The scientific facts about the virulence of SARS-CoV-2 affecting the immune system are of great importance for proposed comparative analyses. Various immunological methods can be employed to elucidate infection-acquired and vaccine-induced immunity against SARS-CoV-2. The safe vaccination of subjects with and without COVID-19 history may disrupt the virus spreading and end the pandemic.","PeriodicalId":388483,"journal":{"name":"Central Asian Journal of Medical Hypotheses and Ethics","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128764367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-04-02DOI: 10.47316/CAJMHE.2021.2.1.02
J. Beall
In this opinion article, the author describes his experiences of naming, listing, and analyzing predatory journals. The gold open-access model has led to the creation of many predatory journals that exist only to exploit researchers. Medical research is the most valuable research for humans, so we must guard against the publishing of medical research in predatory journals. Community-based journals that combine a geographical and a disciplinary focus may be seen as a defense against the pathological nature of predatory publishers.
{"title":"OPEN ACCESS, RESEARCH COMMUNITIES, AND A DEFENSE AGAINST PREDATORY JOURNALS","authors":"J. Beall","doi":"10.47316/CAJMHE.2021.2.1.02","DOIUrl":"https://doi.org/10.47316/CAJMHE.2021.2.1.02","url":null,"abstract":"In this opinion article, the author describes his experiences of naming, listing, and analyzing predatory journals. The gold open-access model has led to the creation of many predatory journals that exist only to exploit researchers. Medical research is the most valuable research for humans, so we must guard against the publishing of medical research in predatory journals. Community-based journals that combine a geographical and a disciplinary focus may be seen as a defense against the pathological nature of predatory publishers.","PeriodicalId":388483,"journal":{"name":"Central Asian Journal of Medical Hypotheses and Ethics","volume":"53 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115098189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-08-07DOI: 10.47316/cajmhe.2020.1.1.11
H. Rivera
Although the variety of research malpractices in low- and middle-income countries (LMIC) is similar to those documented in developed nations, authorship misuse and related issues appear to be more prevalent in the former. This article focuses on some authorship-related topics in LMIC, namely authorship disputes, excessive co-authorship and monetary incentives, authorship issues in student-mentor relationships, and authorship patterns in North-South collaborations. Universities and official bodies in LMIC must supervise the integrity of the whole research process, provide instructions on responsible research and authorship, set up the required postgraduate training programs, foster good role models in authorship, and designate an ombudsperson to advice and respond to complaints of researchers, especially students and junior faculty. Lastly, a recent framework that combines descriptive and normative elements and then uses proper metaphors to achieve an ethical definition of authorship useful in international settings is highlighted.
{"title":"AUTHORSHIP MALPRACTICES IN DEVELOPING COUNTRIES","authors":"H. Rivera","doi":"10.47316/cajmhe.2020.1.1.11","DOIUrl":"https://doi.org/10.47316/cajmhe.2020.1.1.11","url":null,"abstract":"Although the variety of research malpractices in low- and middle-income countries (LMIC) is similar to those documented in developed nations, authorship misuse and related issues appear to be more prevalent in the former. This article focuses on some authorship-related topics in LMIC, namely authorship disputes, excessive co-authorship and monetary incentives, authorship issues in student-mentor relationships, and authorship patterns in North-South collaborations. Universities and official bodies in LMIC must supervise the integrity of the whole research process, provide instructions on responsible research and authorship, set up the required postgraduate training programs, foster good role models in authorship, and designate an ombudsperson to advice and respond to complaints of researchers, especially students and junior faculty. Lastly, a recent framework that combines descriptive and normative elements and then uses proper metaphors to achieve an ethical definition of authorship useful in international settings is highlighted.","PeriodicalId":388483,"journal":{"name":"Central Asian Journal of Medical Hypotheses and Ethics","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125669911","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-08-07DOI: 10.47316/cajmhe.2020.1.1.07
E. D. Batu
Familial Mediterranean fever (FMF) is the most common autoinflammatory disease associated with mutations in the MEFV gene encoding Pyrin. MEFV mutations are frequent in the Mediterranean region. Increased resistance to an infection endemic to this area could have caused a selective advantage for individuals with MEFV mutations. Recent studies have shown that Pyrin is a part of host defense against microorganisms and it gets activated after sensing Rho GTPase inactivation by bacteria such as Clostridium difficile or Yersinia pestis. However, Yersinia species have another effector molecule, YopM which inhibits Pyrin in addition to RhoA modifiers YopE and YopT. Continuously overactive Pyrin in individuals with MEFV mutations could be a good host defense against Yersinia infections. Y. pestis causes plague, which led to a devastating pandemic in the Mediterranean basin. Thus, plague could be the infection which caused a selective biologic advantage for MEFV mutation carriers in this area.
{"title":"A HYPOTHETICAL ROLE FOR PLAGUE IN THE SELECTION OF MEFV MUTATION CARRIERS IN THE MEDITERRANEAN AREA","authors":"E. D. Batu","doi":"10.47316/cajmhe.2020.1.1.07","DOIUrl":"https://doi.org/10.47316/cajmhe.2020.1.1.07","url":null,"abstract":"Familial Mediterranean fever (FMF) is the most common autoinflammatory disease associated with mutations in the MEFV gene encoding Pyrin. MEFV mutations are frequent in the Mediterranean region. Increased resistance to an infection endemic to this area could have caused a selective advantage for individuals with MEFV mutations. Recent studies have shown that Pyrin is a part of host defense against microorganisms and it gets activated after sensing Rho GTPase inactivation by bacteria such as Clostridium difficile or Yersinia pestis. However, Yersinia species have another effector molecule, YopM which inhibits Pyrin in addition to RhoA modifiers YopE and YopT. Continuously overactive Pyrin in individuals with MEFV mutations could be a good host defense against Yersinia infections. Y. pestis causes plague, which led to a devastating pandemic in the Mediterranean basin. Thus, plague could be the infection which caused a selective biologic advantage for MEFV mutation carriers in this area.","PeriodicalId":388483,"journal":{"name":"Central Asian Journal of Medical Hypotheses and Ethics","volume":"126 ","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"113992227","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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