Pub Date : 2024-06-05DOI: 10.4038/sljch.v53i2.11028
B. J. C. Perera
No abstract
无摘要
{"title":"The impact of the exodus of professionals on Sri Lankan Paediatric Healthcare","authors":"B. J. C. Perera","doi":"10.4038/sljch.v53i2.11028","DOIUrl":"https://doi.org/10.4038/sljch.v53i2.11028","url":null,"abstract":"No abstract","PeriodicalId":38870,"journal":{"name":"Sri Lanka Journal of Child Health","volume":"45 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141382143","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-06-05DOI: 10.4038/sljch.v53i2.9430
Pathum Sookaromdee, V. Wiwanitkit
No abstract available
无摘要
{"title":"DPB1 variant rs9277534 frequency and dengue shock syndrome in Indochina: An observation on population genetic and clinical epidemiology association","authors":"Pathum Sookaromdee, V. Wiwanitkit","doi":"10.4038/sljch.v53i2.9430","DOIUrl":"https://doi.org/10.4038/sljch.v53i2.9430","url":null,"abstract":"No abstract available","PeriodicalId":38870,"journal":{"name":"Sri Lanka Journal of Child Health","volume":"58 16","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141384296","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-03-05DOI: 10.4038/sljch.v53i1.10946
S. Mettananda
No abstract avaialble
无摘要
{"title":"GDF15 molecule is responsible for low body mass index in children with thalassaemia","authors":"S. Mettananda","doi":"10.4038/sljch.v53i1.10946","DOIUrl":"https://doi.org/10.4038/sljch.v53i1.10946","url":null,"abstract":"No abstract avaialble","PeriodicalId":38870,"journal":{"name":"Sri Lanka Journal of Child Health","volume":"36 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140263351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-03-05DOI: 10.4038/sljch.v53i1.10612
D. S. G. Punchihewa, J. R. Fonseka, R. N. Jayarathne, K. Dayasiri, K. H. T. I. Sumanasekera, R. M. A. N. Dayarathna, M. V. D. Nawarathne
No abstract available
无摘要
{"title":"Congenital central hypoventilation syndrome: A rare disorder in a neonate","authors":"D. S. G. Punchihewa, J. R. Fonseka, R. N. Jayarathne, K. Dayasiri, K. H. T. I. Sumanasekera, R. M. A. N. Dayarathna, M. V. D. Nawarathne","doi":"10.4038/sljch.v53i1.10612","DOIUrl":"https://doi.org/10.4038/sljch.v53i1.10612","url":null,"abstract":"No abstract available","PeriodicalId":38870,"journal":{"name":"Sri Lanka Journal of Child Health","volume":"41 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140263386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-03-05DOI: 10.4038/sljch.v53i1.10691
Partha Pratim Halder, P. Ranjit, B. Das, Subhajit Dey Sarkar
Background: Enteric fever is caused by Salmonella enterica serovar typhi and Paratyphi A, B and C. Blood culture is the gold standard for diagnosis, but is not always feasible due to logistical issues. This may delay definite diagnosis and treatment resulting in increased complications.Objectives: To document the spectrum of complications involving different organ systems in blood-culture positive enteric cases Method: This was a single centre retrospective observational study conducted in the Institute of Child Health (ICH), Kolkata, India. The study period was from January 2013 to December 2022. Children aged 6 months to 15 years, admitted in ICH, with a history of fever of any duration, whose blood culture revealed Salmonella species were included. Clinical symptoms, complications and the outcome of treatment were noted. Data were statistically analysed using SPSS software.Results: Around one third of the total study population presented with complications. Age group of 5-10 years was the most vulnerable for the infection and its complications. Central nervous system (CNS) involvement, hepato-biliary involvement and gastrointestinal (GI) involvement were the common complications.Conclusions: Enteric fever involved a broad spectrum of complications involving the CNS, hepato-biliary system and the GI system.
{"title":"Spectrum of complications in blood culture positive enteric fever in children aged 1-15 years: A 10-year-experience from a tertiary care centre in Eastern India","authors":"Partha Pratim Halder, P. Ranjit, B. Das, Subhajit Dey Sarkar","doi":"10.4038/sljch.v53i1.10691","DOIUrl":"https://doi.org/10.4038/sljch.v53i1.10691","url":null,"abstract":"Background: Enteric fever is caused by Salmonella enterica serovar typhi and Paratyphi A, B and C. Blood culture is the gold standard for diagnosis, but is not always feasible due to logistical issues. This may delay definite diagnosis and treatment resulting in increased complications.Objectives: To document the spectrum of complications involving different organ systems in blood-culture positive enteric cases Method: This was a single centre retrospective observational study conducted in the Institute of Child Health (ICH), Kolkata, India. The study period was from January 2013 to December 2022. Children aged 6 months to 15 years, admitted in ICH, with a history of fever of any duration, whose blood culture revealed Salmonella species were included. Clinical symptoms, complications and the outcome of treatment were noted. Data were statistically analysed using SPSS software.Results: Around one third of the total study population presented with complications. Age group of 5-10 years was the most vulnerable for the infection and its complications. Central nervous system (CNS) involvement, hepato-biliary involvement and gastrointestinal (GI) involvement were the common complications.Conclusions: Enteric fever involved a broad spectrum of complications involving the CNS, hepato-biliary system and the GI system.","PeriodicalId":38870,"journal":{"name":"Sri Lanka Journal of Child Health","volume":"20 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140264694","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-03-05DOI: 10.4038/sljch.v53i1.10620
B. T. Hettiarachchi, S. D. Ananda, T. Seevarathnam, M. F. M. Nasoor, Medha Weeresekera
No abstract avialable
无抽象可言
{"title":"Congenital pulmonary airway malformation with spontaneous regression in an extremely preterm baby from Sri Lanka","authors":"B. T. Hettiarachchi, S. D. Ananda, T. Seevarathnam, M. F. M. Nasoor, Medha Weeresekera","doi":"10.4038/sljch.v53i1.10620","DOIUrl":"https://doi.org/10.4038/sljch.v53i1.10620","url":null,"abstract":"No abstract avialable","PeriodicalId":38870,"journal":{"name":"Sri Lanka Journal of Child Health","volume":"202 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140265461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-03-05DOI: 10.4038/sljch.v53i1.10641
Gouri Chandrapalsing Rajput, Sara Subodh Dhanawade
Introduction: Acute kidney injury (AKI) is a commonly encountered problem in the paediatric intensive care unit (PICU). There are limited reports on paediatric AKI from the Indian subcontinent. Objective: To determine the incidence, aetiology and outcome in paediatric AKI using Acute Kidney Injury Network (AKIN) criteria. Method: This prospective observational study was conducted in the PICU of a teaching hospital in Western Maharashtra, India, from July 2016 to June 2017 on patients aged 1 month to 17 years. Results: The incidence of AKI was 18.8% (80/426). The mean age was 70 ± 60 months. Most (66.3%) cases had stage I AKI and 54% developed AKI within 72 hours. Sepsis (35%), pneumonia (25%) and tropical febrile illnesses (18.7%) were the common aetiologies. Complete recovery (CR) was seen in 79% and partial recovery (PR) in 21%. CR was highest in stage I (91%) as compared to stages II and III (p=0.005). Mortality was 22% (18/80). Mortality significantly increased with the stage of AKI (p=0.003). Mechanical ventilation, inotrope support, shock and the stage of AKI had a significant association with mortality on bivariate analysis. Mechanical ventilation was found to be a significant independent predictor of mortality (p= 0.011). Renal replacement therapy was needed in 6 (8%) cases. Conclusions: About one-fifth of children admitted to ICU developed AKI and most experienced mild transient AKI. Moderate to severe AKI carried high mortality suggesting a dose-response effect. Infections remain the commonest cause and mechanical ventilation was an independent predictor of mortality.
简介急性肾损伤（AKI）是儿科重症监护室（PICU）经常遇到的问题。印度次大陆有关儿科急性肾损伤的报道十分有限。研究目的采用急性肾损伤网络（AKIN）标准确定儿科 AKI 的发病率、病因和预后。方法：在印度次大陆进行前瞻性观察研究：这项前瞻性观察研究于 2016 年 7 月至 2017 年 6 月在印度马哈拉施特拉邦西部一家教学医院的 PICU 进行，研究对象为 1 个月至 17 岁的患者：AKI发生率为18.8%（80/426）。平均年龄为 70±60 个月。大多数病例（66.3%）为 I 期 AKI，54%的病例在 72 小时内发生 AKI。常见病因为败血症（35%）、肺炎（25%）和热带发热性疾病（18.7%）。79%的患者完全康复（CR），21%的患者部分康复（PR）。 与 II 期和 III 期相比，I 期的 CR 率最高（91%）（P=0.005）。死亡率为 22%（18/80）。死亡率随着 AKI 阶段的增加而明显上升（P=0.003）。在双变量分析中，机械通气、肌力支持、休克和 AKI 阶段与死亡率有显著关联。机械通气是死亡率的重要独立预测因素（p= 0.011）。6例（8%）患儿需要肾脏替代治疗：入住重症监护病房的儿童中约有五分之一出现了AKI，其中大多数都有轻度一过性AKI。 中度至重度 AKI 会导致高死亡率，这表明存在剂量反应效应。感染仍然是最常见的原因，机械通气是预测死亡率的一个独立因素。
{"title":"Clinical profile and outcome of acute kidney injury in children admitted to paediatric intensive care unit: A prospective observational study","authors":"Gouri Chandrapalsing Rajput, Sara Subodh Dhanawade","doi":"10.4038/sljch.v53i1.10641","DOIUrl":"https://doi.org/10.4038/sljch.v53i1.10641","url":null,"abstract":"Introduction: Acute kidney injury (AKI) is a commonly encountered problem in the paediatric intensive care unit (PICU). There are limited reports on paediatric AKI from the Indian subcontinent. \u0000Objective: To determine the incidence, aetiology and outcome in paediatric AKI using Acute Kidney Injury Network (AKIN) criteria. \u0000Method: This prospective observational study was conducted in the PICU of a teaching hospital in Western Maharashtra, India, from July 2016 to June 2017 on patients aged 1 month to 17 years.\u0000Results: The incidence of AKI was 18.8% (80/426). The mean age was 70 ± 60 months. Most (66.3%) cases had stage I AKI and 54% developed AKI within 72 hours. Sepsis (35%), pneumonia (25%) and tropical febrile illnesses (18.7%) were the common aetiologies. Complete recovery (CR) was seen in 79% and partial recovery (PR) in 21%. CR was highest in stage I (91%) as compared to stages II and III (p=0.005). Mortality was 22% (18/80). Mortality significantly increased with the stage of AKI (p=0.003). Mechanical ventilation, inotrope support, shock and the stage of AKI had a significant association with mortality on bivariate analysis. Mechanical ventilation was found to be a significant independent predictor of mortality (p= 0.011). Renal replacement therapy was needed in 6 (8%) cases.\u0000Conclusions: About one-fifth of children admitted to ICU developed AKI and most experienced mild transient AKI. Moderate to severe AKI carried high mortality suggesting a dose-response effect. Infections remain the commonest cause and mechanical ventilation was an independent predictor of mortality. ","PeriodicalId":38870,"journal":{"name":"Sri Lanka Journal of Child Health","volume":"39 5-6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140263332","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-03-05DOI: 10.4038/sljch.v53i1.10682
K. Paul, Anindita Maiti, Susmita Chaudhuri, Mahuya Lahiri, Biswadip Chattopadhyay
Introduction: Self-medication/self-prescription, the practice of using measures to treat and handle diseases, without consulting appropriate authority, has been significantly inculcated in modern society. Parental self-medication is today a significant paediatric public health problem contributing to global rise of antimicrobial resistance.Objectives: To assess the magnitude and determinants of parental self-medication among children attending a tertiary care hospital in Kolkata. Method: This cross-sectional study was conducted on parents of 105 children attending the paediatric clinic of a tertiary care hospital in Kolkata. Universal sampling was employed. Parents were surveyed by face-to-face interview using a pre-tested semi-structured interview schedule validated by subject experts. Information on pattern, reasons, and perception of parental self-medication were elicited from the schedule. Microsoft Excel and STATA MP16 were used for statistical analysis. Results: Mean ages of the parents and their children were 31.79±5.6 years, and 5.3±2.9 years respectively. Prevalence of parental self-medication was 78.1% (95% CI: 69-85%). Analgesic-antipyretics were the most common type of medicine used during self-medication (77.1%), whereas prior experience in dealing with similar illness was the most common reason (42%) for practising self-medication. Higher educational levelof respondent parent and increased age of child (>3 years) were significantly associated with the practice of self-medication in bivariate analysis.Conclusions: Prevalence of parental self-medication was 78.1%. Analgesic-antipyretics were used during self-medication in 77.1% cases. Prior experience in dealing with similar illness was the reason for practising self-medication in 42% cases. Higher educational level of the respondent parent and increased age of child (>3 years) were significantly associated with the practice of self-medication.
引言自我药疗/自我处方，即在未咨询适当权威机构的情况下使用各种措施治疗和处理疾病的做法，在现代社会中已被广泛灌输。如今，家长自行用药已成为一个严重的儿科公共卫生问题，导致全球抗菌药耐药性上升：评估在加尔各答一家三级医院就诊的儿童中家长自行用药的严重程度和决定因素。 研究方法这项横断面研究针对加尔各答一家三级医院儿科诊所就诊的 105 名儿童的家长。采用了普遍抽样法。研究人员使用事先经过测试并经专家确认的半结构化访谈表，通过面对面访谈的方式对家长进行了调查。从访谈表中了解了家长自我用药的模式、原因和看法。统计分析使用 Microsoft Excel 和 STATA MP16。 结果父母及其子女的平均年龄分别为（31.79±5.6）岁和（5.3±2.9）岁。父母自行用药的比例为 78.1%（95% CI：69-85%）。止痛退烧药是自我医疗中最常用的药物类型（77.1%），而之前处理类似疾病的经验是自我医疗最常见的原因（42%）。在双变量分析中，受访家长受教育程度越高、孩子年龄越大（大于 3 岁），与自我药疗的发生率就越高：父母自行用药的比例为 78.1%。77.1%的病例在自行用药时使用镇痛退烧药。在 42% 的病例中，之前处理类似疾病的经验是进行自我药疗的原因。受访家长的教育程度较高和孩子年龄增大（大于 3 岁）与自我药疗有明显关系。
{"title":"A hospital-based cross-sectional study on parental self‑medication among children in a tertiary care hospital in Kolkata","authors":"K. Paul, Anindita Maiti, Susmita Chaudhuri, Mahuya Lahiri, Biswadip Chattopadhyay","doi":"10.4038/sljch.v53i1.10682","DOIUrl":"https://doi.org/10.4038/sljch.v53i1.10682","url":null,"abstract":"Introduction: Self-medication/self-prescription, the practice of using measures to treat and handle diseases, without consulting appropriate authority, has been significantly inculcated in modern society. Parental self-medication is today a significant paediatric public health problem contributing to global rise of antimicrobial resistance.Objectives: To assess the magnitude and determinants of parental self-medication among children attending a tertiary care hospital in Kolkata. Method: This cross-sectional study was conducted on parents of 105 children attending the paediatric clinic of a tertiary care hospital in Kolkata. Universal sampling was employed. Parents were surveyed by face-to-face interview using a pre-tested semi-structured interview schedule validated by subject experts. Information on pattern, reasons, and perception of parental self-medication were elicited from the schedule. Microsoft Excel and STATA MP16 were used for statistical analysis. Results: Mean ages of the parents and their children were 31.79±5.6 years, and 5.3±2.9 years respectively. Prevalence of parental self-medication was 78.1% (95% CI: 69-85%). Analgesic-antipyretics were the most common type of medicine used during self-medication (77.1%), whereas prior experience in dealing with similar illness was the most common reason (42%) for practising self-medication. Higher educational levelof respondent parent and increased age of child (>3 years) were significantly associated with the practice of self-medication in bivariate analysis.Conclusions: Prevalence of parental self-medication was 78.1%. Analgesic-antipyretics were used during self-medication in 77.1% cases. Prior experience in dealing with similar illness was the reason for practising self-medication in 42% cases. Higher educational level of the respondent parent and increased age of child (>3 years) were significantly associated with the practice of self-medication.","PeriodicalId":38870,"journal":{"name":"Sri Lanka Journal of Child Health","volume":"4 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140263372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-03-05DOI: 10.4038/sljch.v53i1.10736
H. Mittal, P. Jain, S. Biradar, T. Jhajhria, Sunaina, Arvind Ahujha
No abstract available
无摘要
{"title":"Interesting aetiology in an adolescent male with pulmonary-renal manifestations: Granulomatosis with poliangiitis","authors":"H. Mittal, P. Jain, S. Biradar, T. Jhajhria, Sunaina, Arvind Ahujha","doi":"10.4038/sljch.v53i1.10736","DOIUrl":"https://doi.org/10.4038/sljch.v53i1.10736","url":null,"abstract":"No abstract available","PeriodicalId":38870,"journal":{"name":"Sri Lanka Journal of Child Health","volume":"128 43","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140079030","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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