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Characteristics of asthmatic children with Mycoplasma pneumoniae infection in Vietnam 越南感染肺炎支原体的哮喘儿童的特征
Q4 Medicine Pub Date : 2024-03-05 DOI: 10.4038/sljch.v53i1.10672
N. Bui, Cuong Thi Kim Mai, N. K. Nguyen, Thang Nguyen, L. M. Duong
Introduction: Mycoplasma pneumoniae is regarded as an involved factor in refractory asthma exacerbations. The link between Mycoplasma pneumoniae infection and asthma is not fully understood, particularly regarding clinical and paraclinical characteristics.Objectives: To determine the frequency of Mycoplasma pneumoniae infection in asthmatic children, identify clinical and paraclinical characteristics along with clinical management in children aged 6 to 15 years at Can Tho Children's Hospital, Vietnam.Method: From March 2019 to April 2021, 124 patients participated in a cross-sectional study that was done. Mycoplasma pneumoniae was detected using an immunoglobulin N (IgM) serology test.Results: Mycoplasma pneumoniae-IgM serology was positive in 32.3% asthmatic children. IgM-positive individuals had significantly greater percentages of accessory respiratory muscle contraction, coarse crackles, fever, and increased heart rate. Mycoplasma pneumoniae infection occurred in 42.3% of children who were hospitalized for the first time and had asthma diagnosis. Mycoplasma pneumoniae infection and the severity of acute asthma exacerbations had a positive association (p<0.05). A longer hospital stay (6.74±1.91 days) and a higher exacerbation recurrence rate (32.4%) were observed in the IgM-positive group (p<0.05). Conclusions: Mycoplasma pneumoniae infections were highly prevalent in asthmatic children. Severity of acute asthma exacerbations, first-time asthma diagnosis, and recurrence of asthma exacerbation were significantly associated with Mycoplasma pneumoniae infection.
导言:肺炎支原体被认为是导致难治性哮喘加重的一个因素。肺炎支原体感染与哮喘之间的关系尚未完全明了,特别是在临床和辅助临床特征方面:确定越南芹苴儿童医院 6 至 15 岁哮喘儿童中肺炎支原体感染的频率,识别临床和辅助临床特征以及临床管理:2019年3月至2021年4月,124名患者参与了横断面研究。采用免疫球蛋白 N(IgM)血清学检测法检测肺炎支原体:结果:32.3%的哮喘儿童肺炎支原体血清学检测呈阳性。IgM 阳性者出现辅助呼吸肌收缩、粗噼啪声、发热和心率加快的比例明显更高。42.3% 首次住院并被诊断为哮喘的儿童感染了肺炎支原体。肺炎支原体感染与哮喘急性加重的严重程度呈正相关(P<0.05)。IgM阳性组住院时间更长(6.74±1.91 天),病情加重复发率更高(32.4%)(P<0.05)。结论肺炎支原体感染在哮喘儿童中非常普遍。哮喘急性加重的严重程度、首次哮喘诊断和哮喘加重的复发与肺炎支原体感染有显著相关性。
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引用次数: 0
Presentation of posterior tongue-tie in a young infant mimicking oral candidiasis: A diagnostic challenge 年幼婴儿后舌系带的表现模仿口腔念珠菌病:诊断难题
Q4 Medicine Pub Date : 2024-03-05 DOI: 10.4038/sljch.v53i1.10615
K. Dayasiri, Nayani Suraweera, Jayne Joyce, Ulrike Uhlig
No abstract avialable 
无抽象可言
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引用次数: 0
Pseudo-achondroplasia masquerading as rickets due to a novel mutation in COMP gene COMP基因的新型突变导致伪装成佝偻病的假性软骨软化症
Q4 Medicine Pub Date : 2024-03-05 DOI: 10.4038/sljch.v53i1.10621
Debashree Priyadarshini, O. Y. P. K. Reddy, Basudev Biswal, Jasashree Choudhury
No abstract available
无摘要
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引用次数: 0
Application of management algorithm to a series of patients of disorders of sexual differentiation from Southern India: A case series  在印度南部一系列性分化障碍患者中应用管理算法:病例系列
Q4 Medicine Pub Date : 2024-03-05 DOI: 10.4038/sljch.v53i1.10603
Ankur Rawat, S. D. Utpal, Sudhanshu Tiwari, Deepu V. Joy, Apoorv Saxena
No abstract available
无摘要
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引用次数: 0
Molecular genetic surveillance of important infectious disease and calculation for mutation rate: a simple but not-to-be-forgotten error regarding accumulation effect 重要传染病的分子遗传监测和突变率计算:关于累积效应的一个简单但不容忽视的错误
Q4 Medicine Pub Date : 2024-03-05 DOI: 10.4038/sljch.v53i1.9664
S. Tin, V. Wiwanitkit
No abstract available
无摘要
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引用次数: 0
Mortality prognostic ability of PRISM, PIM-3, and PELOD-2 in paediatric multiple organ dysfunction syndrome PRISM、PIM-3 和 PELOD-2 预测儿科多器官功能障碍综合征死亡率的能力
Q4 Medicine Pub Date : 2024-03-05 DOI: 10.4038/sljch.v53i1.10899
Phuong Minh Nguyen, Ly Cong Tran
No abstract available
无摘要
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引用次数: 0
The role of preoperative appendicular magnetic resonance imaging in cases of acute bone and joint infection in the paediatric age group 术前阑尾磁共振成像在儿科急性骨关节感染病例中的作用
Q4 Medicine Pub Date : 2024-03-05 DOI: 10.4038/sljch.v53i1.10653
Srijay Sashaank Srinivasan, Gopinath Menon
Background: Acute haematogenous osteomyelitis is mainly a disease of children. It is a challenge to differentiate it from septic arthritis as they have overlapping signs and symptoms. Septic arthritis is a surgical emergency while acute osteomyelitis, when presenting early, can be treated with parenteral antibiotics. There is paucity in imaging guidelines and treatment for cases where acute septic arthritis is associated with osteomyelitis.Objectives: To analyse the role of preoperative magnetic resonance imaging (MRI) in cases of suspected acute bone and joint infection in the paediatric age group.Method: This is a prospective study in 38 children suspected to have acute bone and joint infections. All the patients underwent emergency appendicular MRI on suspicion of bone and joint infections. Based on the MRI findings, the patients were classified into cases of isolated septic arthritis and cases of septic arthritis with concomitant osteomyelitis. There was a change in the treatment modality between the two categories of patients. Results: In our study 14 (36.8%) cases of suspected bone and joint infection had concomitant osteomyelitis with septic arthritis. These 14 cases were seen involving the knee, hip, elbow and shoulder joints. The incidence of septic arthritis with coexisting osteomyelitis was 36.8% in our study, which was diagnosed with preoperative emergency appendicular MRI.Conclusions: Our study concludes that MRI should be included in the work up for suspected bone and joint infections provided MRI is done in a timely fashion without unnecessarily delaying surgical intervention if needed.
背景:急性血源性骨髓炎主要是儿童疾病:急性血源性骨髓炎主要是儿童疾病。由于两者的症状和体征相似,因此很难将其与化脓性关节炎区分开来。化脓性关节炎是一种外科急症,而急性骨髓炎如果出现得早,可以通过肠外抗生素治疗。对于急性化脓性关节炎伴发骨髓炎的病例,影像学指南和治疗方法还很缺乏:分析术前磁共振成像(MRI)在儿科急性骨关节感染疑似病例中的作用:这是一项前瞻性研究,对象是38名疑似急性骨关节感染的儿童。所有患者均因怀疑骨关节感染而接受了急诊阑尾磁共振成像检查。根据磁共振成像结果,将患者分为孤立的化脓性关节炎病例和化脓性关节炎合并骨髓炎病例。两类患者的治疗方式有所变化。研究结果在我们的研究中,有 14 例(36.8%)疑似骨关节感染患者同时患有骨髓炎和化脓性关节炎。这 14 个病例涉及膝关节、髋关节、肘关节和肩关节。在我们的研究中,化脓性关节炎并发骨髓炎的发生率为 36.8%,这是在术前急诊阑尾磁共振成像检查中确诊的:我们的研究得出结论:磁共振成像应被纳入疑似骨与关节感染的检查项目中,但前提是磁共振成像必须及时进行,以免不必要地延误必要的手术治疗。
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引用次数: 0
Effectiveness of reframing as behaviour management technique in paediatric dentistry: A scoping review 重新构思作为儿童牙科行为管理技术的有效性:范围审查
Q4 Medicine Pub Date : 2024-03-05 DOI: 10.4038/sljch.v53i1.10778
Vidyavathi H Patil, S. Hugar, Niraj S. Gokhale, Shweta Kajjari, N. Kohli, Chandrashekar M. Badakar
Background: For children with fear and anxiety, dental appointments are considered as stressful situations. The dental literature has mentioned various behaviour management techniques used to reduce the dental fear and anxiety. Reframing is one such technique which is used for behaviour management with wide applications in health sciences. Hence, exploring this technique in the dental literature is of prime importance.Objectives: This scoping review aims to identify the evidence on the effectiveness of reframing as behaviour management technique in children undergoing dental treatment in the available literature.Method: The Joanna Briggs Institute methodology for scoping reviews is followed in this study and relevant published data from case reports, randomized and nonrandomized controlled clinical trials and literature reviews published without restricting time line till August 2023 from online databases of PubMed, Scopus, ProQuest were assessed by two reviewers for their suitability with our aim of study. The data were synthesized using content analysis.Results: Through literature search, 108 articles were found based on search strategy. After screening the titles, keywords and abstract and removing the duplicates only 10 articles were included for full text review. In the end only 5 articles were included for scoping review for their content analysis.Conclusions: The searched literature has revealed that reframing had changed the behaviour of the child towards dental outcomes but the literature is sparse regarding behaviour management technique for children to alleviate fear and anxiety. Also, there were no clinical trials done to know the efficacy of this technique and means to measure the outcome.
背景介绍对于患有恐惧和焦虑症的儿童来说,看牙医被认为是一种压力。牙科文献中提到了用于减少牙科恐惧和焦虑的各种行为管理技巧。重塑是其中一种用于行为管理的技术,在健康科学中有着广泛的应用。因此,在牙科文献中探究这种技术是非常重要的:本范围综述旨在从现有文献中找出有关重塑作为行为管理技术对接受牙科治疗的儿童的有效性的证据:本研究采用乔安娜-布里格斯研究所(Joanna Briggs Institute)的范围界定综述方法,由两名审稿人对PubMed、Scopus、ProQuest等在线数据库中截至2023年8月发表的病例报告、随机和非随机对照临床试验以及文献综述中的相关公开数据进行评估,以确定其是否符合我们的研究目的。结果:通过文献检索,根据检索策略共找到 108 篇文章。在对标题、关键词和摘要进行筛选并删除重复文章后,只有 10 篇文章被纳入全文审阅。最后只有 5 篇文章被纳入范围审查,对其进行内容分析:检索到的文献显示,重塑法改变了儿童对牙科治疗结果的行为,但有关儿童行为管理技术以减轻恐惧和焦虑的文献却很少。此外,也没有进行临床试验来了解这种技术的有效性和衡量结果的方法。
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引用次数: 0
Serum anion gap versus lactate clearance as mortality predictors in critically ill children 血清阴离子间隙与乳酸清除率是预测重症儿童死亡率的指标
Q4 Medicine Pub Date : 2024-03-05 DOI: 10.4038/sljch.v53i1.10657
Sheza Abootty, S. Rao, Vijaya D. Shenoy, Amiya Ameer
Introduction: Mortality prediction is important for optimal resource allocation in the paediatric intensive care unit (PICU). Objectives: To estimate the predictive value of serum corrected anion gap (cAG) and lactate clearance for predicting mortality in PICU.   Method: We conducted a prospective study of children admitted to the PICU of a tertiary hospital. PRISM III and IV score, cAG and lactate clearance were done in all patients, and the predictive value was calculated for mortality.     Results: The mortality in the study group was 12%. The cAG was significantly lower in survivors than in non-survivors (p <0.001). The lactate levels at 6 hours (AUC 0.898) had the best mortality prediction, followed by admission lactate (AUC 0.804) and cAG (AUC 0.742). However, the lactate clearance did not show good predictive value.  Conclusions: The cAG is an excellent mortality predictor in a low-resource setting.  
简介死亡率预测对于优化儿科重症监护室(PICU)的资源分配非常重要。研究目的估计血清校正阴离子间隙(cAG)和乳酸清除率对预测 PICU 死亡率的预测价值。 方法: 我们对 PICU 中的儿童进行了前瞻性研究:我们对一家三甲医院 PICU 的住院患儿进行了前瞻性研究。对所有患者进行 PRISM III 和 IV 评分、cAG 和乳酸清除率检查,并计算死亡率的预测值。 结果显示研究组的死亡率为 12%。幸存者的 cAG 明显低于非幸存者(P <0.001)。6 小时乳酸水平(AUC 0.898)对死亡率的预测效果最好,其次是入院乳酸(AUC 0.804)和 cAG(AUC 0.742)。然而,乳酸清除率并没有显示出良好的预测价值。 结论在资源匮乏的环境中,cAG 是一个很好的死亡率预测指标。
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引用次数: 0
Adiponectin index to assess metabolic syndrome and insulin resistance in obese adolescents 评估肥胖青少年代谢综合征和胰岛素抵抗的脂肪连接蛋白指数
Q4 Medicine Pub Date : 2024-03-05 DOI: 10.4038/sljch.v53i1.10678
Nur Aisiyah Widjaja, R. Irawan, Meta Herdiana Hanindita, Eva Ardianah
Background: Adiponectin level is decreased in obesity, and is suspected to be the cause of metabolic syndrome (MetS) and even linked with the onset of insulin resistance (IR). Adiponectin index (AI) has been used to determine IR and MetS in polycystic ovary syndrome (POCS).Objectives: To assess the usefulness of AI to determine IR and MetS in obese adolescents.Method: A cross sectional study was performed in obese adolescents from January to May 2020 in Sidoarjo and Surabaya Junior/High School, Indonesia.Results: AI had a weak negative correlation with body weight, waist circumference, hip circumference and body mass index. AI also correlated with triglyceride, systolic blood pressure, fasting insulin, homeostatic model assessment for IR (HOMA-IR) and high-density lipoprotein cholesterol HDL-c. Obese adolescent with MetS had bigger AI than non-MetS (0.21+ 0.18 vs. 0.13+0.09, p=0.0000). A similar phenomenon was seen in obese adolescents with IR (0.37+0.51 vs. 0.11+0.07, p=0.000). AI had a better prognostic value to determine IR than MetS, with larger area under curve (AUC), 0.890 vs. 0.606. Cut-off value to determine IR was <0.17, with sensitivity 81.3% and specificity 88.5%.Conclusions: AI is better to determine IR than MetS with a cut-off of <0.17 in obese adolescents.
背景:肥胖症患者体内的脂肪连接蛋白水平降低,被怀疑是代谢综合征(MetS)的病因,甚至与胰岛素抵抗(IR)的发生有关。多囊卵巢综合征(POCS)的胰岛素抵抗(IR)和代谢综合征(MetS)可通过脂肪连接素指数(AI)来判断:评估 AI 在确定肥胖青少年 IR 和 MetS 中的作用:方法:2020年1月至5月,在印度尼西亚锡多阿若和泗水初中/高中对肥胖青少年进行了一项横断面研究:结果:AI 与体重、腰围、臀围和体重指数呈弱负相关。AI还与甘油三酯、收缩压、空腹胰岛素、红细胞内稳态模型评估(HOMA-IR)和高密度脂蛋白胆固醇HDL-c相关。患有 MetS 的肥胖青少年的 AI 比非 MetS 青少年大(0.21+0.18 vs. 0.13+0.09,P=0.0000)。患有 IR 的肥胖青少年也出现了类似的现象(0.37+0.51 vs. 0.11+0.07,P=0.000)。与 MetS 相比,AI 在确定 IR 方面具有更好的预后价值,其曲线下面积(AUC)更大,为 0.890 对 0.606。确定 IR 的临界值为 <0.17,灵敏度为 81.3%,特异度为 88.5%:结论:在肥胖青少年中,以<0.17为临界值,AI比MetS更能确定IR。
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引用次数: 0
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Sri Lanka Journal of Child Health
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