Pub Date : 2024-03-05DOI: 10.4038/sljch.v53i1.10672
N. Bui, Cuong Thi Kim Mai, N. K. Nguyen, Thang Nguyen, L. M. Duong
Introduction: Mycoplasma pneumoniae is regarded as an involved factor in refractory asthma exacerbations. The link between Mycoplasma pneumoniae infection and asthma is not fully understood, particularly regarding clinical and paraclinical characteristics.Objectives: To determine the frequency of Mycoplasma pneumoniae infection in asthmatic children, identify clinical and paraclinical characteristics along with clinical management in children aged 6 to 15 years at Can Tho Children's Hospital, Vietnam.Method: From March 2019 to April 2021, 124 patients participated in a cross-sectional study that was done. Mycoplasma pneumoniae was detected using an immunoglobulin N (IgM) serology test.Results: Mycoplasma pneumoniae-IgM serology was positive in 32.3% asthmatic children. IgM-positive individuals had significantly greater percentages of accessory respiratory muscle contraction, coarse crackles, fever, and increased heart rate. Mycoplasma pneumoniae infection occurred in 42.3% of children who were hospitalized for the first time and had asthma diagnosis. Mycoplasma pneumoniae infection and the severity of acute asthma exacerbations had a positive association (p<0.05). A longer hospital stay (6.74±1.91 days) and a higher exacerbation recurrence rate (32.4%) were observed in the IgM-positive group (p<0.05). Conclusions: Mycoplasma pneumoniae infections were highly prevalent in asthmatic children. Severity of acute asthma exacerbations, first-time asthma diagnosis, and recurrence of asthma exacerbation were significantly associated with Mycoplasma pneumoniae infection.
{"title":"Characteristics of asthmatic children with Mycoplasma pneumoniae infection in Vietnam","authors":"N. Bui, Cuong Thi Kim Mai, N. K. Nguyen, Thang Nguyen, L. M. Duong","doi":"10.4038/sljch.v53i1.10672","DOIUrl":"https://doi.org/10.4038/sljch.v53i1.10672","url":null,"abstract":"Introduction: Mycoplasma pneumoniae is regarded as an involved factor in refractory asthma exacerbations. The link between Mycoplasma pneumoniae infection and asthma is not fully understood, particularly regarding clinical and paraclinical characteristics.Objectives: To determine the frequency of Mycoplasma pneumoniae infection in asthmatic children, identify clinical and paraclinical characteristics along with clinical management in children aged 6 to 15 years at Can Tho Children's Hospital, Vietnam.Method: From March 2019 to April 2021, 124 patients participated in a cross-sectional study that was done. Mycoplasma pneumoniae was detected using an immunoglobulin N (IgM) serology test.Results: Mycoplasma pneumoniae-IgM serology was positive in 32.3% asthmatic children. IgM-positive individuals had significantly greater percentages of accessory respiratory muscle contraction, coarse crackles, fever, and increased heart rate. Mycoplasma pneumoniae infection occurred in 42.3% of children who were hospitalized for the first time and had asthma diagnosis. Mycoplasma pneumoniae infection and the severity of acute asthma exacerbations had a positive association (p<0.05). A longer hospital stay (6.74±1.91 days) and a higher exacerbation recurrence rate (32.4%) were observed in the IgM-positive group (p<0.05). Conclusions: Mycoplasma pneumoniae infections were highly prevalent in asthmatic children. Severity of acute asthma exacerbations, first-time asthma diagnosis, and recurrence of asthma exacerbation were significantly associated with Mycoplasma pneumoniae infection.","PeriodicalId":38870,"journal":{"name":"Sri Lanka Journal of Child Health","volume":"114 25","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140079527","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-03-05DOI: 10.4038/sljch.v53i1.10621
Debashree Priyadarshini, O. Y. P. K. Reddy, Basudev Biswal, Jasashree Choudhury
No abstract available
无摘要
{"title":"Pseudo-achondroplasia masquerading as rickets due to a novel mutation in COMP gene","authors":"Debashree Priyadarshini, O. Y. P. K. Reddy, Basudev Biswal, Jasashree Choudhury","doi":"10.4038/sljch.v53i1.10621","DOIUrl":"https://doi.org/10.4038/sljch.v53i1.10621","url":null,"abstract":"No abstract available","PeriodicalId":38870,"journal":{"name":"Sri Lanka Journal of Child Health","volume":"28 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140263957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-03-05DOI: 10.4038/sljch.v53i1.10603
Ankur Rawat, S. D. Utpal, Sudhanshu Tiwari, Deepu V. Joy, Apoorv Saxena
No abstract available
无摘要
{"title":"Application of management algorithm to a series of patients of disorders of sexual differentiation from Southern India: A case series ","authors":"Ankur Rawat, S. D. Utpal, Sudhanshu Tiwari, Deepu V. Joy, Apoorv Saxena","doi":"10.4038/sljch.v53i1.10603","DOIUrl":"https://doi.org/10.4038/sljch.v53i1.10603","url":null,"abstract":"No abstract available","PeriodicalId":38870,"journal":{"name":"Sri Lanka Journal of Child Health","volume":"46 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140264579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-03-05DOI: 10.4038/sljch.v53i1.9664
S. Tin, V. Wiwanitkit
No abstract available
无摘要
{"title":"Molecular genetic surveillance of important infectious disease and calculation for mutation rate: a simple but not-to-be-forgotten error regarding accumulation effect","authors":"S. Tin, V. Wiwanitkit","doi":"10.4038/sljch.v53i1.9664","DOIUrl":"https://doi.org/10.4038/sljch.v53i1.9664","url":null,"abstract":"No abstract available","PeriodicalId":38870,"journal":{"name":"Sri Lanka Journal of Child Health","volume":"27 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140264516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-03-05DOI: 10.4038/sljch.v53i1.10653
Srijay Sashaank Srinivasan, Gopinath Menon
Background: Acute haematogenous osteomyelitis is mainly a disease of children. It is a challenge to differentiate it from septic arthritis as they have overlapping signs and symptoms. Septic arthritis is a surgical emergency while acute osteomyelitis, when presenting early, can be treated with parenteral antibiotics. There is paucity in imaging guidelines and treatment for cases where acute septic arthritis is associated with osteomyelitis.Objectives: To analyse the role of preoperative magnetic resonance imaging (MRI) in cases of suspected acute bone and joint infection in the paediatric age group.Method: This is a prospective study in 38 children suspected to have acute bone and joint infections. All the patients underwent emergency appendicular MRI on suspicion of bone and joint infections. Based on the MRI findings, the patients were classified into cases of isolated septic arthritis and cases of septic arthritis with concomitant osteomyelitis. There was a change in the treatment modality between the two categories of patients. Results: In our study 14 (36.8%) cases of suspected bone and joint infection had concomitant osteomyelitis with septic arthritis. These 14 cases were seen involving the knee, hip, elbow and shoulder joints. The incidence of septic arthritis with coexisting osteomyelitis was 36.8% in our study, which was diagnosed with preoperative emergency appendicular MRI.Conclusions: Our study concludes that MRI should be included in the work up for suspected bone and joint infections provided MRI is done in a timely fashion without unnecessarily delaying surgical intervention if needed.
{"title":"The role of preoperative appendicular magnetic resonance imaging in cases of acute bone and joint infection in the paediatric age group","authors":"Srijay Sashaank Srinivasan, Gopinath Menon","doi":"10.4038/sljch.v53i1.10653","DOIUrl":"https://doi.org/10.4038/sljch.v53i1.10653","url":null,"abstract":"Background: Acute haematogenous osteomyelitis is mainly a disease of children. It is a challenge to differentiate it from septic arthritis as they have overlapping signs and symptoms. Septic arthritis is a surgical emergency while acute osteomyelitis, when presenting early, can be treated with parenteral antibiotics. There is paucity in imaging guidelines and treatment for cases where acute septic arthritis is associated with osteomyelitis.Objectives: To analyse the role of preoperative magnetic resonance imaging (MRI) in cases of suspected acute bone and joint infection in the paediatric age group.Method: This is a prospective study in 38 children suspected to have acute bone and joint infections. All the patients underwent emergency appendicular MRI on suspicion of bone and joint infections. Based on the MRI findings, the patients were classified into cases of isolated septic arthritis and cases of septic arthritis with concomitant osteomyelitis. There was a change in the treatment modality between the two categories of patients. Results: In our study 14 (36.8%) cases of suspected bone and joint infection had concomitant osteomyelitis with septic arthritis. These 14 cases were seen involving the knee, hip, elbow and shoulder joints. The incidence of septic arthritis with coexisting osteomyelitis was 36.8% in our study, which was diagnosed with preoperative emergency appendicular MRI.Conclusions: Our study concludes that MRI should be included in the work up for suspected bone and joint infections provided MRI is done in a timely fashion without unnecessarily delaying surgical intervention if needed.","PeriodicalId":38870,"journal":{"name":"Sri Lanka Journal of Child Health","volume":"52 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140264557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-03-05DOI: 10.4038/sljch.v53i1.10778
Vidyavathi H Patil, S. Hugar, Niraj S. Gokhale, Shweta Kajjari, N. Kohli, Chandrashekar M. Badakar
Background: For children with fear and anxiety, dental appointments are considered as stressful situations. The dental literature has mentioned various behaviour management techniques used to reduce the dental fear and anxiety. Reframing is one such technique which is used for behaviour management with wide applications in health sciences. Hence, exploring this technique in the dental literature is of prime importance.Objectives: This scoping review aims to identify the evidence on the effectiveness of reframing as behaviour management technique in children undergoing dental treatment in the available literature.Method: The Joanna Briggs Institute methodology for scoping reviews is followed in this study and relevant published data from case reports, randomized and nonrandomized controlled clinical trials and literature reviews published without restricting time line till August 2023 from online databases of PubMed, Scopus, ProQuest were assessed by two reviewers for their suitability with our aim of study. The data were synthesized using content analysis.Results: Through literature search, 108 articles were found based on search strategy. After screening the titles, keywords and abstract and removing the duplicates only 10 articles were included for full text review. In the end only 5 articles were included for scoping review for their content analysis.Conclusions: The searched literature has revealed that reframing had changed the behaviour of the child towards dental outcomes but the literature is sparse regarding behaviour management technique for children to alleviate fear and anxiety. Also, there were no clinical trials done to know the efficacy of this technique and means to measure the outcome.
{"title":"Effectiveness of reframing as behaviour management technique in paediatric dentistry: A scoping review","authors":"Vidyavathi H Patil, S. Hugar, Niraj S. Gokhale, Shweta Kajjari, N. Kohli, Chandrashekar M. Badakar","doi":"10.4038/sljch.v53i1.10778","DOIUrl":"https://doi.org/10.4038/sljch.v53i1.10778","url":null,"abstract":"Background: For children with fear and anxiety, dental appointments are considered as stressful situations. The dental literature has mentioned various behaviour management techniques used to reduce the dental fear and anxiety. Reframing is one such technique which is used for behaviour management with wide applications in health sciences. Hence, exploring this technique in the dental literature is of prime importance.Objectives: This scoping review aims to identify the evidence on the effectiveness of reframing as behaviour management technique in children undergoing dental treatment in the available literature.Method: The Joanna Briggs Institute methodology for scoping reviews is followed in this study and relevant published data from case reports, randomized and nonrandomized controlled clinical trials and literature reviews published without restricting time line till August 2023 from online databases of PubMed, Scopus, ProQuest were assessed by two reviewers for their suitability with our aim of study. The data were synthesized using content analysis.Results: Through literature search, 108 articles were found based on search strategy. After screening the titles, keywords and abstract and removing the duplicates only 10 articles were included for full text review. In the end only 5 articles were included for scoping review for their content analysis.Conclusions: The searched literature has revealed that reframing had changed the behaviour of the child towards dental outcomes but the literature is sparse regarding behaviour management technique for children to alleviate fear and anxiety. Also, there were no clinical trials done to know the efficacy of this technique and means to measure the outcome.","PeriodicalId":38870,"journal":{"name":"Sri Lanka Journal of Child Health","volume":"25 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140264928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-03-05DOI: 10.4038/sljch.v53i1.10657
Sheza Abootty, S. Rao, Vijaya D. Shenoy, Amiya Ameer
Introduction: Mortality prediction is important for optimal resource allocation in the paediatric intensive care unit (PICU). Objectives: To estimate the predictive value of serum corrected anion gap (cAG) and lactate clearance for predicting mortality in PICU. Method: We conducted a prospective study of children admitted to the PICU of a tertiary hospital. PRISM III and IV score, cAG and lactate clearance were done in all patients, and the predictive value was calculated for mortality. Results: The mortality in the study group was 12%. The cAG was significantly lower in survivors than in non-survivors (p <0.001). The lactate levels at 6 hours (AUC 0.898) had the best mortality prediction, followed by admission lactate (AUC 0.804) and cAG (AUC 0.742). However, the lactate clearance did not show good predictive value. Conclusions: The cAG is an excellent mortality predictor in a low-resource setting.
{"title":"Serum anion gap versus lactate clearance as mortality predictors in critically ill children","authors":"Sheza Abootty, S. Rao, Vijaya D. Shenoy, Amiya Ameer","doi":"10.4038/sljch.v53i1.10657","DOIUrl":"https://doi.org/10.4038/sljch.v53i1.10657","url":null,"abstract":"Introduction: Mortality prediction is important for optimal resource allocation in the paediatric intensive care unit (PICU). Objectives: To estimate the predictive value of serum corrected anion gap (cAG) and lactate clearance for predicting mortality in PICU. Method: We conducted a prospective study of children admitted to the PICU of a tertiary hospital. PRISM III and IV score, cAG and lactate clearance were done in all patients, and the predictive value was calculated for mortality. Results: The mortality in the study group was 12%. The cAG was significantly lower in survivors than in non-survivors (p <0.001). The lactate levels at 6 hours (AUC 0.898) had the best mortality prediction, followed by admission lactate (AUC 0.804) and cAG (AUC 0.742). However, the lactate clearance did not show good predictive value. Conclusions: The cAG is an excellent mortality predictor in a low-resource setting. ","PeriodicalId":38870,"journal":{"name":"Sri Lanka Journal of Child Health","volume":"109 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140079350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-03-05DOI: 10.4038/sljch.v53i1.10678
Nur Aisiyah Widjaja, R. Irawan, Meta Herdiana Hanindita, Eva Ardianah
Background: Adiponectin level is decreased in obesity, and is suspected to be the cause of metabolic syndrome (MetS) and even linked with the onset of insulin resistance (IR). Adiponectin index (AI) has been used to determine IR and MetS in polycystic ovary syndrome (POCS).Objectives: To assess the usefulness of AI to determine IR and MetS in obese adolescents.Method: A cross sectional study was performed in obese adolescents from January to May 2020 in Sidoarjo and Surabaya Junior/High School, Indonesia.Results: AI had a weak negative correlation with body weight, waist circumference, hip circumference and body mass index. AI also correlated with triglyceride, systolic blood pressure, fasting insulin, homeostatic model assessment for IR (HOMA-IR) and high-density lipoprotein cholesterol HDL-c. Obese adolescent with MetS had bigger AI than non-MetS (0.21+ 0.18 vs. 0.13+0.09, p=0.0000). A similar phenomenon was seen in obese adolescents with IR (0.37+0.51 vs. 0.11+0.07, p=0.000). AI had a better prognostic value to determine IR than MetS, with larger area under curve (AUC), 0.890 vs. 0.606. Cut-off value to determine IR was <0.17, with sensitivity 81.3% and specificity 88.5%.Conclusions: AI is better to determine IR than MetS with a cut-off of <0.17 in obese adolescents.
背景：肥胖症患者体内的脂肪连接蛋白水平降低，被怀疑是代谢综合征（MetS）的病因，甚至与胰岛素抵抗（IR）的发生有关。多囊卵巢综合征（POCS）的胰岛素抵抗（IR）和代谢综合征（MetS）可通过脂肪连接素指数（AI）来判断：评估 AI 在确定肥胖青少年 IR 和 MetS 中的作用：方法：2020年1月至5月，在印度尼西亚锡多阿若和泗水初中/高中对肥胖青少年进行了一项横断面研究：结果：AI 与体重、腰围、臀围和体重指数呈弱负相关。AI还与甘油三酯、收缩压、空腹胰岛素、红细胞内稳态模型评估（HOMA-IR）和高密度脂蛋白胆固醇HDL-c相关。患有 MetS 的肥胖青少年的 AI 比非 MetS 青少年大（0.21+0.18 vs. 0.13+0.09，P=0.0000）。患有 IR 的肥胖青少年也出现了类似的现象（0.37+0.51 vs. 0.11+0.07，P=0.000）。与 MetS 相比，AI 在确定 IR 方面具有更好的预后价值，其曲线下面积（AUC）更大，为 0.890 对 0.606。确定 IR 的临界值为 <0.17，灵敏度为 81.3%，特异度为 88.5%：结论：在肥胖青少年中，以<0.17为临界值，AI比MetS更能确定IR。
{"title":"Adiponectin index to assess metabolic syndrome and insulin resistance in obese adolescents","authors":"Nur Aisiyah Widjaja, R. Irawan, Meta Herdiana Hanindita, Eva Ardianah","doi":"10.4038/sljch.v53i1.10678","DOIUrl":"https://doi.org/10.4038/sljch.v53i1.10678","url":null,"abstract":"Background: Adiponectin level is decreased in obesity, and is suspected to be the cause of metabolic syndrome (MetS) and even linked with the onset of insulin resistance (IR). Adiponectin index (AI) has been used to determine IR and MetS in polycystic ovary syndrome (POCS).Objectives: To assess the usefulness of AI to determine IR and MetS in obese adolescents.Method: A cross sectional study was performed in obese adolescents from January to May 2020 in Sidoarjo and Surabaya Junior/High School, Indonesia.Results: AI had a weak negative correlation with body weight, waist circumference, hip circumference and body mass index. AI also correlated with triglyceride, systolic blood pressure, fasting insulin, homeostatic model assessment for IR (HOMA-IR) and high-density lipoprotein cholesterol HDL-c. Obese adolescent with MetS had bigger AI than non-MetS (0.21+ 0.18 vs. 0.13+0.09, p=0.0000). A similar phenomenon was seen in obese adolescents with IR (0.37+0.51 vs. 0.11+0.07, p=0.000). AI had a better prognostic value to determine IR than MetS, with larger area under curve (AUC), 0.890 vs. 0.606. Cut-off value to determine IR was <0.17, with sensitivity 81.3% and specificity 88.5%.Conclusions: AI is better to determine IR than MetS with a cut-off of <0.17 in obese adolescents.","PeriodicalId":38870,"journal":{"name":"Sri Lanka Journal of Child Health","volume":"27 20","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140263600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：