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 Mediastinal lymphatic venous malformation mimicking thymic shadow in an Infant 模仿胸腺阴影的婴儿纵隔淋巴管静脉畸形
Q4 Medicine Pub Date : 2024-03-05 DOI: 10.4038/sljch.v53i1.10562
Kaushalya Pussegoda, M. H. A. D. De Silva, H. M. W. Heshantha, W. D. V. Thilakarathna, T. P. M. Dissanayake, P. P. Rajawasam, Janath Liyanage, C. R. Kulatunge, N. Liyanarachchi
No abstract available
无摘要
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引用次数: 0
Do vitamin D levels affect forced expiratory flow 25-75 among children with asthma? 维生素 D 水平是否会影响哮喘儿童的用力呼气流量 25-75?
Q4 Medicine Pub Date : 2024-03-05 DOI: 10.4038/sljch.v53i1.10706
Veena Anand, S. Joseph, I. Yadev
Background: Previous reports of association between vitamin D levels and pulmonary function based on forced expiratory volume in one second (FEV1) and ratio of FEV1 to forced vital capacity (FEV1/FVC) gave mixed results. Forced expiratory flow 25-75 (FEF 25-75) is considered a sensitive parameter in children as it is effort independent.Objectives: To assess the correlation between serum vitamin D levels and pulmonary function parameters in children with asthma.Method: This cross-sectional analytic study was conducted at the paediatric respiratory clinic of a tertiary care referral hospital. Children aged 6-12 years, having asthma, on controllers with good compliance and under regular follow-up were enrolled.Results: Mean serum vitamin D level (16.8± 6.69ng/ml) was low and deficiency was seen in 36 (72%) children with asthma. Positive correlation (r=0.41) was seen between serum vitamin D levels and predicted FEF 25-75%. Univariate analysis between vitamin D and FEF 25-75 showed decreased vitamin D levels were associated with significantly low FEF 25-75 (p<0.001). In multivariate linear regression analysis after adjustment for age and sex, the relationship was direct and significant (R2=0.18, p<0.05) but for FEV1 the relationship was not significant (R2=-0.034, p=0.336).Conclusions: Vitamin D levels showed direct and significant relationship with FEF 25-75 outcome in children with asthma.
背景:以往关于维生素 D 水平与一秒钟用力呼气量(FEV1)和 FEV1 与用力肺活量之比(FEV1/FVC)的肺功能之间关系的报告结果不一。强制呼气流量 25-75 (FEF 25-75) 被认为是儿童的一个敏感参数,因为它与体力无关:评估哮喘患儿血清维生素 D 水平与肺功能参数之间的相关性:这项横断面分析研究在一家三级医疗转诊医院的儿科呼吸门诊进行。研究对象为年龄在 6-12 岁、患有哮喘、服用控制药物且依从性良好并接受定期随访的儿童:结果:平均血清维生素 D 水平(16.8± 6.69ng/ml)较低,36 名(72%)哮喘儿童缺乏维生素 D。血清维生素 D 水平与预测 FEF 25-75% 之间呈正相关(r=0.41)。维生素 D 和 FEF 25-75 之间的单变量分析表明,维生素 D 水平下降与 FEF 25-75 明显偏低有关(p<0.001)。在调整年龄和性别后的多变量线性回归分析中,两者关系直接且显著(R2=0.18,p<0.05),但与 FEV1 的关系不显著(R2=-0.034,p=0.336):维生素 D 水平与哮喘儿童的 FEF 25-75 结果有直接且显著的关系。
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引用次数: 0
Aetio-pathological profile of anaemic children belonging to upper socioeconomic society in a tertiary care hospital of North India 北印度一家三级医院中社会经济地位较高的贫血儿童的遗传病理学特征
Q4 Medicine Pub Date : 2024-03-05 DOI: 10.4038/sljch.v53i1.10709
Anusha Reddy, Bindu T. Nair, Dasari Varun Kumar
Introduction: Anaemia is a major public health problem especially in the preschool age group. It is rampant even in children of upper and middle classes of the society.Objectives: To study the aetio-pathology of anaemia in children belonging to upper and upper middle socio-economic scale and to correlate it with their nutritional status. Method: It was a cross-sectional descriptive study on 165 preschool children aged 6-59 months who presented with pallor on clinical examination. They were advised to undergo a complete haemogram and further specific tests as required.  Results: The most common cause of anaemia was nutritional, including iron deficiency (92%), combined iron and B12 deficiency (2%) and isolated B12 deficiency (0.6%). Thalassaemia was the next common cause (3%) followed by B-acute lymphoblastic leukaemia (1%) and microangiopathic haemolytic anaemia (0.6%). Maternal education and nutritional awareness had positive correlation with anaemia. Majority of children were normally nourished despite being anaemic, However, undernourished children were more severely anaemic. Conclusions: Nutritional anaemia is the commonest cause of anaemia even in children belonging to higher socio-economic classes.
简介贫血是一个主要的公共健康问题,尤其是在学龄前儿童中。即使在社会中上层阶级的儿童中也很普遍:研究中上层社会经济阶层儿童贫血的病因,并将其与营养状况联系起来。方法:这是一项横断面描述性研究:这是一项横断面描述性研究,研究对象是 165 名 6-59 个月大的学龄前儿童,他们在临床检查时脸色苍白。建议他们进行全面的血常规检查,并根据需要进行进一步的特殊检查。 研究结果最常见的贫血原因是营养性贫血,包括缺铁(92%)、缺铁和缺乏 B12(2%)以及单独缺乏 B12(0.6%)。其次是地中海贫血(3%),然后是 B 型急性淋巴细胞白血病(1%)和微血管病性溶血性贫血(0.6%)。母亲的教育程度和营养意识与贫血呈正相关。大多数儿童虽然贫血,但营养状况正常,但营养不良的儿童贫血更为严重。结论营养性贫血是导致贫血的最常见原因,即使在社会经济地位较高的儿童中也是如此。
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引用次数: 0
Antibiotic resistance pattern of Salmonella enterica typhi infection in paediatric population at a iertiary level hospital 一家三级医院儿科感染伤寒沙门氏菌的抗生素耐药性模式
Q4 Medicine Pub Date : 2024-03-05 DOI: 10.4038/sljch.v53i1.10702
Dasari Varun Kumar, Bindu T. Nair, Anusha Reddy, Manisha Bandari
Background: Enteric fever is an important public health condition in developing countries. Antibiotic resistance patterns in Salmonella enterica typhi (S. typhi) infections are constantly changing. Continual surveillance of resistance levels of S. typhi is critical for clinicians to update antibiotic options.Objectives: To evaluate the current trends in antibiotic sensitivity and resistance to S. typhi in children in developing countries.Method: A cross sectional observational study was carried out on 102 children aged 6 months to 5 years with culture positive S. typhi infection in a tertiary care hospital in North India. Antibiotic susceptibility information of S. typhi was collected and the pattern of antibiotic resistance was analysed.Results: S. typhi showed a sensitivity of 78.4% to ampicillin and 99% to trimethoprim+ sulfamethoxazole which were the previously used antibiotics. However, it showed 100% resistance to ciprofloxacin and nalidixic acid. Of the currently used first line IV antibiotics, there was a 88.4% sensitivity to ceftriaxone and a 98% sensitivity to meropenem.Conclusions: The study concluded that there is reemergence of antibiotic sensitivity of S. typhi to earlier first line drugs like ampicillin and trimethoprim– sulfamethoxazole.
背景:肠热病是发展中国家的一种重要公共卫生疾病。伤寒沙门氏菌(S. typhi)感染的抗生素耐药性模式在不断变化。持续监测伤寒沙门氏菌的耐药性水平对临床医生更新抗生素选择至关重要:评估发展中国家儿童对伤寒杆菌的抗生素敏感性和耐药性的当前趋势:方法:在印度北部的一家三级医院对 102 名 6 个月至 5 岁伤寒杆菌培养阳性的儿童进行了横断面观察研究。收集了伤寒杆菌的抗生素敏感性信息,并对抗生素耐药性模式进行了分析:结果:伤寒杆菌对氨苄西林的敏感性为 78.4%,对三甲氧苄青霉素+磺胺甲噁唑的敏感性为 99%。不过,它对环丙沙星和萘啶酸的耐药性为 100%。在目前使用的一线静脉注射抗生素中,头孢曲松的敏感性为 88.4%,美罗培南的敏感性为 98%:研究得出结论:伤寒杆菌对氨苄西林和三甲双氨-磺胺甲噁唑等早期一线药物的抗生素敏感性再次出现。
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引用次数: 0
The Legacy of late Professor Chandra Kumari Abeysekera: A lady like no other 已故钱德拉-库马里-阿贝塞克拉教授的遗产:独一无二的女士
Q4 Medicine Pub Date : 2023-12-05 DOI: 10.4038/sljch.v52i4.10800
B. J. C. Perera
No abstract available
没有摘要
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引用次数: 0
First reported case of pentalogy of Cantrell in Sri Lanka 斯里兰卡首次报告的坎特雷尔五联症病例
Q4 Medicine Pub Date : 2023-12-05 DOI: 10.4038/sljch.v52i4.10596
A. P. H. Withana, D. Samarasinghe, I. R. Ragunathan, K. Singappuli, Y. Ubaithullah, Nishani Lucas
No abstract available
没有摘要
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引用次数: 0
Phosphorus abnormalities in a paediatric intensive care unit in North India 印度北部一家儿科重症监护室的磷异常情况
Q4 Medicine Pub Date : 2023-12-05 DOI: 10.4038/sljch.v52i4.10619
Taruna Vijaywargiya, Satyajeet Maurya, Sitikant Mohapatra
Introduction: Critical illness triggers severe acute phase response which is associated with several metabolic derangements. Serum phosphorus level abnormalities are common among them and go unnoticed in sick children.Objectives: To determine the prevalence of phosphorus abnormalities in sick children admitted to the paediatric intensive care unit (PICU) and its association with various clinical outcomes.Method: We conducted a prospective, non-interventional study at a PICU in North India. During an 18-month period we investigated the incidence of phosphorus abnormalities in patients admitted to the PICU on admission and followed the course at day 3 and day 7 during their stay.Results: The prevalence of phosphorus level abnormalities was 44.2% on admission to PICU; 34.9% patients had hypophosphataemia while 9.3% had hyperphosphataemia. Hypophosphataemia was significantly associated with severe malnutrition (p=0.041) while hyperphosphataemia was associated with organ failure (p=<0.001). Although the need for mechanical ventilation, duration of PICU stay and mortality were higher in hypophosphataemic patients and PRISM score was higher in hyperphosphataemic patients, these differences were not statistically significant. Changes in the baseline phosphorus levels after PICU stays of 3 days (p=0.346) and of 7 days (p=0.782) were not statistically significant.Conclusions: Phosphorus abnormalities were highly prevalent in ill children admitted in the PICU. Hypophosphatemia was more common and was significantly associated with severe malnutrition while hyperphosphatemia was significantly associated with organ failure.
简介:危重疾病引发严重的急性期反应,这与几种代谢紊乱有关。血清磷水平异常在他们中很常见,而在患病儿童中却未被注意到。目的:确定住院儿科重症监护病房(PICU)患病儿童磷异常的患病率及其与各种临床结果的关系。方法:我们在印度北部的PICU进行了一项前瞻性、非介入性研究。在18个月的时间里,我们调查了PICU入院患者磷异常的发生率,并在住院期间的第3天和第7天随访。结果:入PICU时磷水平异常发生率为44.2%;34.9%的患者低磷血症,9.3%的患者高磷血症。低磷血症与严重营养不良显著相关(p=0.041),而高磷血症与器官衰竭相关(p=<0.001)。虽然低磷血症患者的机械通气需求、PICU住院时间和死亡率较高,高磷血症患者的PRISM评分较高,但这些差异无统计学意义。PICU停留3 d (p=0.346)和7 d (p=0.782)后基线磷水平的变化无统计学意义。结论:磷异常在PICU住院患儿中非常普遍。低磷血症更为常见,与严重营养不良显著相关,而高磷血症与器官衰竭显著相关。
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引用次数: 0
Hypopharyngeal foreign body impaction presenting late as acute onset torticollis due to retropharyngeal abscess formation in a child 儿童咽后脓肿形成导致的咽下异物嵌塞,晚期表现为急性发作的扭颈症
Q4 Medicine Pub Date : 2023-12-05 DOI: 10.4038/sljch.v52i4.10534
Arabi Sooreakumar, D. M. D. T. Dissanayake, Wasana Wijenayake, P. K. B. U. C. Bandara, K. Dayasiri, S. Mettananda
No abstract available
没有摘要
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引用次数: 0
Concern regarding point of care laboratory testing in neonates 对新生儿护理点实验室检测的关注
Q4 Medicine Pub Date : 2023-12-05 DOI: 10.4038/sljch.v52i4.9626
B. Joob, V. Wiwanitkit
No abstract available
没有摘要
{"title":"Concern regarding point of care laboratory testing in neonates","authors":"B. Joob, V. Wiwanitkit","doi":"10.4038/sljch.v52i4.9626","DOIUrl":"https://doi.org/10.4038/sljch.v52i4.9626","url":null,"abstract":"No abstract available","PeriodicalId":38870,"journal":{"name":"Sri Lanka Journal of Child Health","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138601109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Charcot-Marie-Tooth disease with co-occurrence of syringo-hydromyelia 同时伴有梅毒性脊髓灰质炎的夏科-玛丽-牙病
Q4 Medicine Pub Date : 2023-12-05 DOI: 10.4038/sljch.v52i4.10493
S. M. A. S. M. Samarasekara, A. J. Jayawardena, P. D. Rathnayaka, Chathuri Weerasinghe, P. D. P. Udayanga, S. K. V. P. Dissanayake
No abstract available
没有摘要
{"title":"Charcot-Marie-Tooth disease with co-occurrence of syringo-hydromyelia","authors":"S. M. A. S. M. Samarasekara, A. J. Jayawardena, P. D. Rathnayaka, Chathuri Weerasinghe, P. D. P. Udayanga, S. K. V. P. Dissanayake","doi":"10.4038/sljch.v52i4.10493","DOIUrl":"https://doi.org/10.4038/sljch.v52i4.10493","url":null,"abstract":"No abstract available","PeriodicalId":38870,"journal":{"name":"Sri Lanka Journal of Child Health","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138599188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Sri Lanka Journal of Child Health
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