Pub Date : 2024-06-05DOI: 10.4038/sljch.v53i2.10776
A. Juliansen, M. Muljono, C. L. Budiputri, Fellisa Meliani, R. Heriyanto, Shally Chandra, G. Octavius
Background: Dengue infection is still a significant public health problem in Indonesia. An appropriate clinical profile is helpful in early identification of patients with a high risk for severe dengue infection. Objectives: To report the prevalence, characteristics, and clinical outcomes of patients with dengue fever (DF) and dengue haemorrhagic fever (DHF). Method: This was a retrospective study of childhood hospitalisation in Siloam Hospitals Lippo Village, Indonesia from January 2015 to December 2020. Demographic data, clinical signs, and laboratory findings were collected and processed using SPSS version 26. Results: Of 528 patients, 85.6% were DF, 10.4% were DHF grades I and II, and 4% were DHF grades III and IV. Median ages of patients with DF, DHF grades I and II, and DHF grades III and IV were 10.9, 12.4 and 8.5 years respectively. Common clinical symptoms of DF patients were headache (67.5%), loss of appetite (41.8%), and vomiting (40.9%). While 52.7% patients with DHF grades I and II had respiratory symptoms, 42.9% patients with DHF grades III and IV had hepatomegaly. Conclusions: Common clinical symptoms of DF and DHF patients were headache, loss of appetite and vomiting. Whilst 52.7% patients with DHF grades I and II had respiratory symptoms, 42.9% patients with DHF grades III and IV had hepatomegaly.
背景：在印度尼西亚，登革热感染仍然是一个严重的公共卫生问题。适当的临床特征有助于及早发现严重登革热感染的高危患者。研究目的报告登革热（DF）和登革出血热（DHF）患者的发病率、特征和临床结果。方法：这是一项回顾性研究：这是一项回顾性研究，研究对象为2015年1月至2020年12月期间在印尼Siloam医院Lippo村住院治疗的儿童。使用SPSS 26版本收集和处理人口统计学数据、临床症状和实验室结果。 结果在528名患者中，85.6%为DF，10.4%为I级和II级DHF，4%为III级和IV级DHF。DF、DHF I级和II级、DHF III级和IV级患者的中位年龄分别为10.9岁、12.4岁和8.5岁。DF患者的常见临床症状是头痛（67.5%）、食欲不振（41.8%）和呕吐（40.9%）。52.7% 的 DHF I 级和 II 级患者有呼吸道症状，42.9% 的 DHF III 级和 IV 级患者有肝肿大。结论DF和DHF患者的常见临床症状是头痛、食欲不振和呕吐。52.7%的DHF I级和II级患者有呼吸道症状，42.9%的DHF III级和IV级患者有肝肿大。
{"title":"Clinical profile of dengue fever and dengue haemorrhagic fever in Indonesian children: A six year retrospective study","authors":"A. Juliansen, M. Muljono, C. L. Budiputri, Fellisa Meliani, R. Heriyanto, Shally Chandra, G. Octavius","doi":"10.4038/sljch.v53i2.10776","DOIUrl":"https://doi.org/10.4038/sljch.v53i2.10776","url":null,"abstract":"Background: Dengue infection is still a significant public health problem in Indonesia. An appropriate clinical profile is helpful in early identification of patients with a high risk for severe dengue infection. Objectives: To report the prevalence, characteristics, and clinical outcomes of patients with dengue fever (DF) and dengue haemorrhagic fever (DHF). Method: This was a retrospective study of childhood hospitalisation in Siloam Hospitals Lippo Village, Indonesia from January 2015 to December 2020. Demographic data, clinical signs, and laboratory findings were collected and processed using SPSS version 26. Results: Of 528 patients, 85.6% were DF, 10.4% were DHF grades I and II, and 4% were DHF grades III and IV. Median ages of patients with DF, DHF grades I and II, and DHF grades III and IV were 10.9, 12.4 and 8.5 years respectively. Common clinical symptoms of DF patients were headache (67.5%), loss of appetite (41.8%), and vomiting (40.9%). While 52.7% patients with DHF grades I and II had respiratory symptoms, 42.9% patients with DHF grades III and IV had hepatomegaly. Conclusions: Common clinical symptoms of DF and DHF patients were headache, loss of appetite and vomiting. Whilst 52.7% patients with DHF grades I and II had respiratory symptoms, 42.9% patients with DHF grades III and IV had hepatomegaly.","PeriodicalId":38870,"journal":{"name":"Sri Lanka Journal of Child Health","volume":"39 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141383285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-06-05DOI: 10.4038/sljch.v53i2.10803
S. Gaikwad, Punam Uke, Ashwini Kundalwal, Keerti Swarnakar
Background: Infants at risk for developmental delay (DD) have a history of one or more risk factors that occurred during pregnancy, the perinatal period, or after birth. Despite numerous studies on high-risk pregnancies and child development in advanced countries, there is scanty data from developing nations like India. Objectives: To determine the antenatal, natal and postnatal risk factors of DD in children aged 6 months to 6 years. Method: A case-control study comprising 61 infants with DD and 61 controls was carried out at Acharya Vinoba Bhave Rural Hospital, Sawangi (Meghe) in Maharashtra from December 2019 to May 2020. Children with DD were taken as cases and children without DD as controls. A questionnaire delivered to mothers was used to gather data. Data analysis was carried out using STATA, version 10 software. Results: Common risk factors were caesarean sections (55%), infections (58%), and chronic disorders during pregnancy (49%). Maternal infections, chronic diseases during pregnancy, caesarean section, failure to cry after birth and absence of breastfeeding were significantly more in cases compared to controls. Conclusions: In this case-control study, maternal infections, chronic diseases during pregnancy, caesarean section, failure to cry after birth and absence of breastfeeding were risk factors of DD in children aged 6 months to 6 years.
{"title":"Risk factors of developmental delay in children from the age group of 6 months to 6 years","authors":"S. Gaikwad, Punam Uke, Ashwini Kundalwal, Keerti Swarnakar","doi":"10.4038/sljch.v53i2.10803","DOIUrl":"https://doi.org/10.4038/sljch.v53i2.10803","url":null,"abstract":"Background: Infants at risk for developmental delay (DD) have a history of one or more risk factors that occurred during pregnancy, the perinatal period, or after birth. Despite numerous studies on high-risk pregnancies and child development in advanced countries, there is scanty data from developing nations like India. Objectives: To determine the antenatal, natal and postnatal risk factors of DD in children aged 6 months to 6 years. Method: A case-control study comprising 61 infants with DD and 61 controls was carried out at Acharya Vinoba Bhave Rural Hospital, Sawangi (Meghe) in Maharashtra from December 2019 to May 2020. Children with DD were taken as cases and children without DD as controls. A questionnaire delivered to mothers was used to gather data. Data analysis was carried out using STATA, version 10 software. Results: Common risk factors were caesarean sections (55%), infections (58%), and chronic disorders during pregnancy (49%). Maternal infections, chronic diseases during pregnancy, caesarean section, failure to cry after birth and absence of breastfeeding were significantly more in cases compared to controls. Conclusions: In this case-control study, maternal infections, chronic diseases during pregnancy, caesarean section, failure to cry after birth and absence of breastfeeding were risk factors of DD in children aged 6 months to 6 years.","PeriodicalId":38870,"journal":{"name":"Sri Lanka Journal of Child Health","volume":"29 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141384998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-06-05DOI: 10.4038/sljch.v53i2.10955
M. Fernando, R. Siriwardana
No abstract available
无摘要
{"title":"Paediatric liver transplantation in Sri Lanka; From an impossible dream to a lifesaving reality.","authors":"M. Fernando, R. Siriwardana","doi":"10.4038/sljch.v53i2.10955","DOIUrl":"https://doi.org/10.4038/sljch.v53i2.10955","url":null,"abstract":"No abstract available","PeriodicalId":38870,"journal":{"name":"Sri Lanka Journal of Child Health","volume":"45 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141382133","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-06-05DOI: 10.4038/sljch.v53i2.10786
Hasitha Madusanka Dilruk Madura Arachchige
Background: Out-of-hospital cardiac arrest in children is uncommon but significant, with poor survival rates and high morbidity. Choking in children is common but less reported with high mortality. Early commencement of cardiopulmonary resuscitation (CPR) in cardiac arrest or following of choking algorithm in a case of choking is important for survival of the victim. Objectives: To survey the knowledge, awareness and attitudes of parents in Sri Lanka regarding paediatric Basic Life Support (BLS) including early treatment of choking.Method: This was a descriptive cross-sectional study and questionnaires were administered to parents of children managed at the Preliminary Care Unit (PCU) and wards 2 and 4 of Lady Ridgeway Hospital, Colombo from October 2022 to January 2023. Sample size was calculated according to the Lwanga and Lemeshow method. Total respondents were 350 out of total participants of 415. The questionnaire consisted of four sections for assessment of demography, knowledge and attitude. Total scores of each aspect were analysed with respect to different factors.Results: Of the participants, 95% did not have BLS training and the largest proportion of them was educated only up to the General Certificate of Education (GCE) ordinary level. Knowledge of specific aspects of BLS or choking was demonstrated by only about 10% of the population. Nearly 50% of parents had identified substandard common practices as correct methods. There was no statistically significant correlation between total score of each aspect and previous observations, training or highest educational level. It was assessed with 95% confidence interval. However, seeing BLS had improved knowledge of basic health (p=0.013). Conclusions: Seeing the procedure on television or other resources had not improved knowledge of BLS. Workshops were the preferred method to improve their knowledge on BLS including the choking algorithm and participants’ educational level was not important in organizing such an event.
{"title":"Knowledge and awareness of paediatric basic life support among parents in the Lady Ridgeway Hospital for Children, Colombo, Sri Lanka","authors":"Hasitha Madusanka Dilruk Madura Arachchige","doi":"10.4038/sljch.v53i2.10786","DOIUrl":"https://doi.org/10.4038/sljch.v53i2.10786","url":null,"abstract":"Background: Out-of-hospital cardiac arrest in children is uncommon but significant, with poor survival rates and high morbidity. Choking in children is common but less reported with high mortality. Early commencement of cardiopulmonary resuscitation (CPR) in cardiac arrest or following of choking algorithm in a case of choking is important for survival of the victim. Objectives: To survey the knowledge, awareness and attitudes of parents in Sri Lanka regarding paediatric Basic Life Support (BLS) including early treatment of choking.Method: This was a descriptive cross-sectional study and questionnaires were administered to parents of children managed at the Preliminary Care Unit (PCU) and wards 2 and 4 of Lady Ridgeway Hospital, Colombo from October 2022 to January 2023. Sample size was calculated according to the Lwanga and Lemeshow method. Total respondents were 350 out of total participants of 415. The questionnaire consisted of four sections for assessment of demography, knowledge and attitude. Total scores of each aspect were analysed with respect to different factors.Results: Of the participants, 95% did not have BLS training and the largest proportion of them was educated only up to the General Certificate of Education (GCE) ordinary level. Knowledge of specific aspects of BLS or choking was demonstrated by only about 10% of the population. Nearly 50% of parents had identified substandard common practices as correct methods. There was no statistically significant correlation between total score of each aspect and previous observations, training or highest educational level. It was assessed with 95% confidence interval. However, seeing BLS had improved knowledge of basic health (p=0.013). Conclusions: Seeing the procedure on television or other resources had not improved knowledge of BLS. Workshops were the preferred method to improve their knowledge on BLS including the choking algorithm and participants’ educational level was not important in organizing such an event.","PeriodicalId":38870,"journal":{"name":"Sri Lanka Journal of Child Health","volume":"56 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141384073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-06-05DOI: 10.4038/sljch.v53i2.10830
Deepthi Joella Fernandes, Suman Rath
Introduction: Congenital hypothyroidism (CH) is the most commonly identified endocrine disorder. Early intervention can prevent intellectual deficits. Objective: To determine the intelligence quotient (IQ) and aetiology in children diagnosed with CH undergoing treatment and the associations between the IQ and the age of diagnosis. Method: A cross-sectional study was conducted in a tertiary care hospital in Bangalore, which enrolled 52 children aged 6 months to 15 years diagnosed with CH. Using a pre-designed proforma, we collected demographic data and confirmed CH aetiology. For IQ assessment, children under 3 years underwent the Vineland Social Maturity Scale (VSMS) and developmental screening test (DST), while those over 3 years were evaluated with the VSMS and Binet Kamat test of intelligence (BKT). Results: Among the 52 children with CH, dyshormonogenesis was the predominant aetiology. In the under-3-year age group (n=17), all demonstrated average to above-average intelligence. Among those over 3 years (n=35), 10.9% (95% CI: 6.5% to 17.2%) exhibited low average and borderline intelligence with the VSMS, and 5.7% (95% CI: 2.3% to 12.5%) had extremely low IQ (IQ <70). The BKT scale showed 20% (95% CI: 12.8% to 29.7%) with low average and borderline intelligence, and 2.9% (95% CI: 0.7% to 8.3%) with extremely low IQ (IQ <70). Children diagnosed at a mean age of 4.2 and 4.4 years exhibited intellectual disability on the VSMS and BKT scales, respectively. Conversely, those diagnosed at a mean age of 1.2 and 1.8 years showed average and above-average intelligence on the VSMS (p-value 0.02) and BKT scale (p-value 0.001), respectively. Conclusions: Children diagnosed with CH at mean ages of 4.2 and 4.4 years exhibited intellectual disability on the VSMS and BKT scales, respectively. Conversely, those diagnosed with CH at mean ages of 1.2 and 1.8 years showed average and above-average intelligence on the VSMS (p = 0.02) and BKT scale (p = 0.001), respectively.
{"title":"Intelligence quotient in children with congenital hypothyroidism on treatment: A cross-sectional study","authors":"Deepthi Joella Fernandes, Suman Rath","doi":"10.4038/sljch.v53i2.10830","DOIUrl":"https://doi.org/10.4038/sljch.v53i2.10830","url":null,"abstract":"Introduction: Congenital hypothyroidism (CH) is the most commonly identified endocrine disorder. Early intervention can prevent intellectual deficits. Objective: To determine the intelligence quotient (IQ) and aetiology in children diagnosed with CH undergoing treatment and the associations between the IQ and the age of diagnosis. Method: A cross-sectional study was conducted in a tertiary care hospital in Bangalore, which enrolled 52 children aged 6 months to 15 years diagnosed with CH. Using a pre-designed proforma, we collected demographic data and confirmed CH aetiology. For IQ assessment, children under 3 years underwent the Vineland Social Maturity Scale (VSMS) and developmental screening test (DST), while those over 3 years were evaluated with the VSMS and Binet Kamat test of intelligence (BKT). Results: Among the 52 children with CH, dyshormonogenesis was the predominant aetiology. In the under-3-year age group (n=17), all demonstrated average to above-average intelligence. Among those over 3 years (n=35), 10.9% (95% CI: 6.5% to 17.2%) exhibited low average and borderline intelligence with the VSMS, and 5.7% (95% CI: 2.3% to 12.5%) had extremely low IQ (IQ <70). The BKT scale showed 20% (95% CI: 12.8% to 29.7%) with low average and borderline intelligence, and 2.9% (95% CI: 0.7% to 8.3%) with extremely low IQ (IQ <70). Children diagnosed at a mean age of 4.2 and 4.4 years exhibited intellectual disability on the VSMS and BKT scales, respectively. Conversely, those diagnosed at a mean age of 1.2 and 1.8 years showed average and above-average intelligence on the VSMS (p-value 0.02) and BKT scale (p-value 0.001), respectively. Conclusions: Children diagnosed with CH at mean ages of 4.2 and 4.4 years exhibited intellectual disability on the VSMS and BKT scales, respectively. Conversely, those diagnosed with CH at mean ages of 1.2 and 1.8 years showed average and above-average intelligence on the VSMS (p = 0.02) and BKT scale (p = 0.001), respectively.","PeriodicalId":38870,"journal":{"name":"Sri Lanka Journal of Child Health","volume":"50 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141381777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction: The proximity of the mother to the newborn following delivery is essential for the early initiation and establishment of exclusive breast feeding. It leads to the conditioning of the oxytocin reflex, allowing the expression of breast milk. However, preterm and sick babies are nursed in an environment away from their mothers in the NICU, thus leading to delayed initiation and inadequate expression of breast milk. Objective: To estimate the volume of breastmilk expressed close to the baby in comparison to breastmilk expressed away from her baby. Method: This quasi-experimental study was conducted in a tertiary healthcare hospital in Hyderabad over a duration of one month. Postpartum mothers of newborns delivered in this hospital and admitted to the NICU were included in the study. The enrolled mothers were shown a video and poster on manual expression of breast milk and were assisted by lactational counselors for support. The enrolled mothers initially expressed milk in the mother’s room, and an average of three expressions was taken. The next day, the mother was asked to go near the baby in the NICU and express milk in front of her baby, and the average of three feeds was determined in a similar fashion. Data analysis was done using a paired t-test. Results: A total of 30 postnatal mothers were enrolled in the study. The mean volume of breast milk expressed by the mother in the mother’s room was 9.9 ± 2.5ml and the mean volume of breast milk obtained when expressed close to her baby in the newborn care unit was 11.2 ± 2.7ml. The volume of milk expressed near the baby was significantly higher when compared to milk expressed away from the newborn (p<0.001). Conclusions: This study showed that mothers who expressed their feed near their admitted newborns in the newborn care unit had a significant increase in the volume of expressed breastmilk in comparison to expressing the milk away from their babies.
简介分娩后，母亲与新生儿的接近对于早期开始和建立纯母乳喂养至关重要。它能调节催产素反射，使母乳得以分泌。然而，在新生儿重症监护室中，早产儿和患病婴儿的哺乳环境远离母亲，从而导致母乳喂养的启动延迟和母乳表达不足。目的估计靠近婴儿挤出的母乳量与远离婴儿挤出的母乳量的比较。研究方法这项准实验研究在海德拉巴一家三级医疗保健医院进行，为期一个月。在该医院分娩并住进新生儿重症监护室的新生儿的产后母亲被纳入研究范围。参加研究的母亲观看了人工挤奶的视频和海报，并得到了哺乳顾问的协助和支持。登记的母亲最初在母亲的房间里挤奶，平均挤奶三次。第二天，母亲被要求到新生儿重症监护室的婴儿附近，当着婴儿的面挤奶，并以类似的方式测定三次挤奶的平均值。数据分析采用配对 t 检验。结果共有 30 名产后母亲参加了研究。母亲在母婴室挤出的母乳量平均为（9.9 ± 2.5）毫升，在新生儿护理室靠近婴儿挤出的母乳量平均为（11.2 ± 2.7）毫升。在婴儿附近挤出的母乳量明显高于远离新生儿挤出的母乳量（P<0.001）。结论这项研究表明，在新生儿护理病房靠近新生儿挤奶的母亲与远离新生儿挤奶的母亲相比，挤出的母乳量明显增加。
{"title":"To study the impact of expressing breastmilk inside the neonatal intensive care unit (NICU) besides a neonate, in comparison to expression outside the NICU: A quasi experimental study","authors":"Tejaswi Reddy, Swapna Lingaldinna, Kotha Rakesh, Sadiqua Anjum, Alimelu Madireddy","doi":"10.4038/sljch.v53i2.10825","DOIUrl":"https://doi.org/10.4038/sljch.v53i2.10825","url":null,"abstract":"Introduction: The proximity of the mother to the newborn following delivery is essential for the early initiation and establishment of exclusive breast feeding. It leads to the conditioning of the oxytocin reflex, allowing the expression of breast milk. However, preterm and sick babies are nursed in an environment away from their mothers in the NICU, thus leading to delayed initiation and inadequate expression of breast milk. Objective: To estimate the volume of breastmilk expressed close to the baby in comparison to breastmilk expressed away from her baby. Method: This quasi-experimental study was conducted in a tertiary healthcare hospital in Hyderabad over a duration of one month. Postpartum mothers of newborns delivered in this hospital and admitted to the NICU were included in the study. The enrolled mothers were shown a video and poster on manual expression of breast milk and were assisted by lactational counselors for support. The enrolled mothers initially expressed milk in the mother’s room, and an average of three expressions was taken. The next day, the mother was asked to go near the baby in the NICU and express milk in front of her baby, and the average of three feeds was determined in a similar fashion. Data analysis was done using a paired t-test. Results: A total of 30 postnatal mothers were enrolled in the study. The mean volume of breast milk expressed by the mother in the mother’s room was 9.9 ± 2.5ml and the mean volume of breast milk obtained when expressed close to her baby in the newborn care unit was 11.2 ± 2.7ml. The volume of milk expressed near the baby was significantly higher when compared to milk expressed away from the newborn (p<0.001). Conclusions: This study showed that mothers who expressed their feed near their admitted newborns in the newborn care unit had a significant increase in the volume of expressed breastmilk in comparison to expressing the milk away from their babies.","PeriodicalId":38870,"journal":{"name":"Sri Lanka Journal of Child Health","volume":"5 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141385533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-06-05DOI: 10.4038/sljch.v53i2.10667
M. N. F. Shafana, Darshika Gunawardana, M. N. Jiffry
No abstract available
无摘要
{"title":"A child with dyskeratosis congenita with TINF2 mutation","authors":"M. N. F. Shafana, Darshika Gunawardana, M. N. Jiffry","doi":"10.4038/sljch.v53i2.10667","DOIUrl":"https://doi.org/10.4038/sljch.v53i2.10667","url":null,"abstract":"No abstract available","PeriodicalId":38870,"journal":{"name":"Sri Lanka Journal of Child Health","volume":"14 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141384915","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-06-05DOI: 10.4038/sljch.v53i2.10700
Manasi Gupta, Ramesh Bhat
No abstract available
无摘要
{"title":"Haemophagocytic lymphohistiocytosis: A rare initial presentation of microscopic polyangiitis in a three-year-old girl","authors":"Manasi Gupta, Ramesh Bhat","doi":"10.4038/sljch.v53i2.10700","DOIUrl":"https://doi.org/10.4038/sljch.v53i2.10700","url":null,"abstract":"No abstract available","PeriodicalId":38870,"journal":{"name":"Sri Lanka Journal of Child Health","volume":"47 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141382119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-06-05DOI: 10.4038/sljch.v53i2.10723
R. Prihaningtyas, Bagus Setyoboedi, S. Arief
Introduction: Biliary atresia is a hepatobiliary disease which frequently results in portal hypertension.Objectives: To analyse the risk factors for portal hypertension in children with biliary atresia.Method: A case-controlled study was performed on 96 children with biliary atresia. Subjects were enrolled based on the inclusion and exclusion criteria. Medical history, physical examination results, imaging data, and laboratory examination results were collected prospectively. Patients were divided into two groups based on the signs of portal hypertension clinically during the follow-up period. Risk factors for portal hypertension were analysed using SPSS. Univariate analysis was used first to identify possible risk factors. A multivariate analysis was performed using logistic regression with p significant <0.05.Results: The median age was 18.21 (3.14-128.86) weeks in the portal hypertension group and 9.07 (1.00-50.57) weeks in the non-portal hypertension group. Age, duration of illness, birth weight, gestational age, and laboratory examination [Haemoglobin (Hb), white blood cell (WBC) count, albumin, direct bilirubin, total bilirubin, prothrombin time (PT), gamma-glutamyl transferase (GGT), aspartate transaminase (AST), and AST: alanine transaminase (ALT) ratio] were significantly different in the 2 groups (p<0.05). For every one-week increase in the subject's age, the risk of portal hypertension increased by 1.127. For every one unit increase in Hb, PT, GGT, and the AST:ALT ratio, the risk of having portal hypertension was 0.746, 1.125, 1.00, and 2.862 in children with biliary atresia (p<0,05).Conclusions: The risk factors for portal hypertension in children with biliary atresia were age, Hb, PT, GGT levels, and the AST:ALT ratio.
{"title":"Risk factors for portal hypertension in children with biliary atresia","authors":"R. Prihaningtyas, Bagus Setyoboedi, S. Arief","doi":"10.4038/sljch.v53i2.10723","DOIUrl":"https://doi.org/10.4038/sljch.v53i2.10723","url":null,"abstract":"Introduction: Biliary atresia is a hepatobiliary disease which frequently results in portal hypertension.Objectives: To analyse the risk factors for portal hypertension in children with biliary atresia.Method: A case-controlled study was performed on 96 children with biliary atresia. Subjects were enrolled based on the inclusion and exclusion criteria. Medical history, physical examination results, imaging data, and laboratory examination results were collected prospectively. Patients were divided into two groups based on the signs of portal hypertension clinically during the follow-up period. Risk factors for portal hypertension were analysed using SPSS. Univariate analysis was used first to identify possible risk factors. A multivariate analysis was performed using logistic regression with p significant <0.05.Results: The median age was 18.21 (3.14-128.86) weeks in the portal hypertension group and 9.07 (1.00-50.57) weeks in the non-portal hypertension group. Age, duration of illness, birth weight, gestational age, and laboratory examination [Haemoglobin (Hb), white blood cell (WBC) count, albumin, direct bilirubin, total bilirubin, prothrombin time (PT), gamma-glutamyl transferase (GGT), aspartate transaminase (AST), and AST: alanine transaminase (ALT) ratio] were significantly different in the 2 groups (p<0.05). For every one-week increase in the subject's age, the risk of portal hypertension increased by 1.127. For every one unit increase in Hb, PT, GGT, and the AST:ALT ratio, the risk of having portal hypertension was 0.746, 1.125, 1.00, and 2.862 in children with biliary atresia (p<0,05).Conclusions: The risk factors for portal hypertension in children with biliary atresia were age, Hb, PT, GGT levels, and the AST:ALT ratio.","PeriodicalId":38870,"journal":{"name":"Sri Lanka Journal of Child Health","volume":"24 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141386133","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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