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Retrospective study on endoscopic findings of gastritis in children attending the gastrointestinal tract endoscopic unit of Assiut University Children Hospital over a 15-year-period 对阿苏特大学儿童医院胃肠道内窥镜室 15 年间就诊儿童胃炎内窥镜检查结果的回顾性研究
Q4 Medicine Pub Date : 2023-12-05 DOI: 10.4038/sljch.v52i4.10588
Naglaa Hassan Abu Faddan, Hamada Mohamed Reyad, Amira M. Shalaby
Background: Children with gastritis typically exhibit recurrent stomach pain and dyspepsia or vomiting.Objectives: To assess the frequency, clinical manifestations, endoscopic pictures, aetiology and outcome of gastritis in children who visited the gastrointestinal tract (GIT) endoscopic unit of Assiut University Children Hospital.Method: This was a retrospective, crosssectional study conducted at Assiut University Children Hospital GIT Endoscopic Unit from 1st January 2005 to 31st December 2019.Results: Upper GI endoscopy, done in all cases, showed that 66 (8.1%) had erythematous gastric mucosa, 106 (13%) had nodular gastric mucosa, 212 (25.9%) had erythematous gastric mucosa and hyperaemia, 147 (18%) had erythematous gastric mucosa and nodularity, 156 (19.1%) had hyperaemic mucosa and petechiae, 77 (9.5%) had hyperaemic mucosa and erosion, and 53 (6.5%) had multiple erosions and ulcers.Conclusions: Gastritis represented 9.4% of children who underwent upper GI endoscopy. Helicobacter pylori was the commonest cause with high recurrence. Patients presented with recurrent GI bleeding, and those with erythematous hyperaemic mucosa on endoscopy showed recurrence compared to their counterparts.
背景:胃炎患儿通常表现为反复胃痛、消化不良或呕吐。目的:了解在阿西尤特大学儿童医院胃肠道内镜科室就诊的儿童胃炎的发生率、临床表现、内镜图片、病因及转归。方法:这是一项回顾性横断面研究,于2005年1月1日至2019年12月31日在阿西尤特大学儿童医院GIT内镜部门进行。结果:所有病例均行上消化道内镜检查,胃黏膜红斑66例(8.1%),胃黏膜结节106例(13%),胃黏膜红斑伴充血212例(25.9%),胃黏膜红斑伴结节147例(18%),黏膜充血伴瘀点156例(19.1%),黏膜充血伴糜烂77例(9.5%),多发性糜烂伴溃疡53例(6.5%)。结论:胃炎占接受上消化道内镜检查的儿童的9.4%。幽门螺杆菌是最常见的病因,复发率高。患者表现为复发性胃肠道出血,内镜检查显示有红斑性充血粘膜的患者出现复发。
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引用次数: 0
Successful re-vascularisation following renal angioplasty in a child with Takayasu arteritis 高安动脉炎患儿肾血管成形术后成功再通血管
Q4 Medicine Pub Date : 2023-12-05 DOI: 10.4038/sljch.v52i4.10591
Sikha Agarwal, Shreepal Jain, S. Venkatesh
No abstract available
没有摘要
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引用次数: 0
Liver dysfunction in children with scrub typhus: association with severity of illness and outcome 恙虫病患儿的肝功能异常:与病情严重程度和预后的关系
Q4 Medicine Pub Date : 2023-12-05 DOI: 10.4038/sljch.v52i4.10614
Sandeep Kumar, Sowmya Manda Sai, S. Shashidhara, P. Kini, Shrikiran Aroor, Suneel C Mundkur
Background: Liver dysfunction is a common finding in children with scrub typhus. Adult literature has found a significant association between the extent of liver dysfunction and severity of illness and outcome. However, very few studies are available on children.Objectives: To study the extent of liver dysfunction in children with scrub typhus and its association with severity of illness and outcome.Method: It was a retrospective descriptive study conducted on children diagnosed with scrub typhus admitted to a tertiary care centre in south India from January 2016 to December 2020. Children from 1 month to 18 years of age were included. Demographic data, clinical details, laboratory parameters, course of illness and outcome data were collected and analysed. Results: Study population included 143 cases of scrub typhus. Mean age of the study population was 8.4 ± 4.4 years with a male: female ratio of 1.2:1. Fever was present in 100%, myalgia in 54.5%, decreased appetite in 54.5%, jaundice in 8.4% and hepatomegaly in 71.3% of children. Abnormal liver function tests were present in 75.5% children. Elevated aspartate transaminase (AST) was seen in 75.5%, elevated alanine transaminase (ALT) in   67.1%, hypoalbuminaemia in 47.5% and severe hypoalbuminaemia (<2.5g/dL) in 29.4%. Complications included meningitis (13.3%), shock (7.6%), meningoencephalitis (2.7%) and acute respiratory distress syndrome (2%). There were 2 (1.3%) deaths. Children with complications had higher AST (p <0.01), ALT (p = 0.018), low serum albumin (p<0.001) and prolonged international normalised ratio (INR) (p =0.003).Conclusions: Abnormal liver function tests were present in 75.5% of children with scrub typhus. Children with complications of scrub typhus had significantly higher median AST levels, ALT levels, low serum albumin levels and prolonged INR compared to children with no complications
背景:肝功能障碍是儿童恙虫病的常见表现。成人文献已经发现肝功能障碍的程度与疾病的严重程度和结果之间存在显著的关联。然而,很少有关于儿童的研究。目的:研究小儿恙虫病肝功能障碍程度及其与疾病严重程度和转归的关系。方法:对2016年1月至2020年12月在印度南部一家三级保健中心确诊为恙虫病的儿童进行回顾性描述性研究。包括1个月至18岁的儿童。收集和分析人口统计资料、临床细节、实验室参数、病程和结局数据。结果:研究人群包括143例恙虫病。研究人群的平均年龄为8.4±4.4岁,男女比例为1.2:1。发热占100%,肌痛占54.5%,食欲下降占54.5%,黄疸占8.4%,肝肿大占71.3%。75.5%的儿童肝功能检查异常。天冬氨酸转氨酶(AST)升高占75.5%,谷丙转氨酶(ALT)升高占67.1%,低白蛋白血症占47.5%,重度低白蛋白血症(<2.5g/dL)占29.4%。并发症包括脑膜炎(13.3%)、休克(7.6%)、脑膜脑炎(2.7%)和急性呼吸窘迫综合征(2%)。2例(1.3%)死亡。并发症患儿AST (p< 0.01)、ALT (p = 0.018)升高,血清白蛋白(p<0.001)降低,国际正常化比(INR)延长(p =0.003)。结论:恙虫病患儿肝功能检查异常占75.5%。与无并发症的儿童相比,有恙虫病并发症的儿童AST水平、ALT水平中位数显著升高,血清白蛋白水平低,INR延长
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引用次数: 0
Length of stay and hospitalisation rates in Indonesian patients with paediatric hepatitis A: 2015-2021 印度尼西亚儿童甲型肝炎患者的住院时间和住院率:2015-2021 年
Q4 Medicine Pub Date : 2023-12-05 DOI: 10.4038/sljch.v52i4.10616
Andraina, A. Juliansen, M. G. Vanessa, G. Octavius, R. Heriyanto, M. Muljono, C. L. Budiputri
Objective: To describe the trend in hepatitis-A virus (HAV)-related hospitalisations in children and analyse the association of demographic, clinical and laboratory manifestations with length of stay (LOS) of HAV infection.Method: A retrospective study was conducted in Siloam Hospitals Indonesia. Inclusion criteria were hospitalised paediatric hepatitis A patients aged 3-17 years from 2015-2021. Another viral hepatitis was excluded. Total 58 samples were divided into non-prolonged group (LOS<5 days) and prolonged group (LOS≥5 days). Demographic data, clinical manifestations and laboratory parameters were collected and analysed using SPSS. Correlations with p <0.05 were considered significant.Results: Hospitalisation rate pattern showed two peaks in 2016 and in 2019. The monocyte-to-leucocyte ratio (MLR), blood urea nitrogen (BUN), and creatinine were significantly associated with LOS in bivariate analysis. Medians of MLR and BUN were higher in the prolonged group (0.23; 17) than in the non-prolonged group (0.19; 15.98). Median of creatinine was lower in the prolonged group (0.55) than in the non-prolonged group (0.74). Multivariate analysis found that dark urine was less likely to have a prolonged LOS (OR: 0.23; 95% CI 0.06-0.91, p = 0.04).Conclusions: Dark urine was a protective factor for prolonged LOS. Independently, higher BUN and higher MLR were risk factors for prolonged LOS.
目的:了解儿童甲型肝炎(HAV)相关住院趋势,分析人口统计学、临床和实验室表现与HAV感染住院时间(LOS)的关系。方法:在印度尼西亚西罗亚医院进行回顾性研究。纳入标准为2015-2021年住院的3-17岁儿科甲型肝炎患者。排除另一例病毒性肝炎。58例患者分为非延长组(生存时间<5天)和延长组(生存时间≥5天)。统计资料、临床表现及实验室参数,采用SPSS软件进行分析。p <0.05认为相关性显著。结果:2016年和2019年住院率呈现两个高峰。在双变量分析中,单核细胞与白细胞比(MLR)、血尿素氮(BUN)和肌酐与LOS显著相关。延长组MLR和BUN中位数较高(0.23;17)比非延长组(0.19;15.98)。延长组肌酐中位数(0.55)低于未延长组(0.74)。多变量分析发现,深色尿液不太可能延长LOS (OR: 0.23;95% CI 0.06-0.91, p = 0.04)。结论:深尿是延长LOS的保护因素。独立地,较高的BUN和较高的MLR是延长LOS的危险因素。
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引用次数: 0
A case of neonatal association of cystic fibrosis with cholestatic jaundice and intestinal hypoganglionosis 一例新生儿囊性纤维化合并胆汁淤积性黄疸和肠道功能减退症病例
Q4 Medicine Pub Date : 2023-12-05 DOI: 10.4038/sljch.v52i4.10590
Aditi Rawat, Sagar A. Karotkar, M. Lakra, Kiran Khedkar, B. Lakhkar
No abstract available
没有摘要
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引用次数: 0
An unusual case of arthropod dermatosis: A disorder of Cydnidae pigmentation (the burrowing bug) 节肢动物皮肤病的一个不寻常病例:穴居昆虫色素沉着症
Q4 Medicine Pub Date : 2023-12-05 DOI: 10.4038/sljch.v52i4.10572
Apparanjitha V. Ramanan, A. P. Krithika, S. Sundari
No abstract available
没有摘要
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引用次数: 0
Neonate of Jehovah witness parents 耶和华见证人父母的新生儿
Q4 Medicine Pub Date : 2023-12-05 DOI: 10.4038/sljch.v52i4.10539
Anil Kallesh, Vikram Sakleshpur Kumar, S. R. Dhananjaya, Shivaraj Gowda
No absteact available
没有摘要
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引用次数: 0
Usage patterns of electronic devices for communication and prevalence of nomophobia among General Certificate of Education Advanced Level students in Colombo, Sri Lanka 斯里兰卡科伦坡普通教育证书高级水平学生使用电子设备进行交流的模式和 "恐名症 "的流行程度
Q4 Medicine Pub Date : 2023-12-05 DOI: 10.4038/sljch.v52i4.10618
H. G. Liyanaarachchi, D. Samaranayake, H. L. Vinod, M. S. Jayawardana, V. P. Wickramasinghe
Introduction: Nomophobia is becoming an increasing concern as a result of inappropriate use of electronic communication devices.Objectives: To describe the pattern of use of electronic communication devices and the prevalence of nomophobia among General Certificate of Education (GCE) Advanced Level (A/L) students in Colombo Educational Zone.Method: This descriptive cross-sectional study was carried out from January to March 2020 in six of the randomly selected government and government approved private schools within the Colombo Education Zone. A self-administered questionnaire including a culturally adapted nomophobia-questionnaire was used. Data were analysed using SPSS-20.Results: Of 337 students, 336 (99.7%) were regularly using a device for communication, the most preferred (n=319) being mobile phone; 213 owned a mobile phone; 60.4% were spending ≥2 hours/day with these devices, 10.1% spending >5 hours/day. Common uses of devices were listening to music (96.7%), taking photos (85.4%), sending text messages (84.8%) and academic activities (84.5%). Prevalence of moderate and severe nomophobia was 49.8% and 34.2% respectively. Prevalence of severe nomophobia was significantly higher in females (p<0.001) and those studying in grade 13 (p=0.036), government schools (p=0.002), Sinhala-medium (p=0.017) and Science stream (p=0.024).Conclusions:  Among GCE A/L students in Colombo, Sri Lanka, 99.7% were regularly using a device for communication. Prevalence of moderate and severe nomophobia was 49.8% and 34.2% respectively.
导读:由于不恰当地使用电子通讯设备,“无手机恐惧症”正日益受到关注。目的:描述科伦坡教育区普通教育证书(GCE)高级水平(A/L)学生中电子通信设备的使用模式和无手机恐惧症的流行情况。方法:本描述性横断面研究于2020年1月至3月在科伦坡教育区内随机选择的6所政府和政府批准的私立学校进行。使用了一份自我管理的问卷,其中包括一份与文化相适应的无恐惧症问卷。数据采用SPSS-20进行分析。结果:337名学生中,有336人(99.7%)经常使用通讯工具,其中最常用的通讯工具是手机(n=319);213人拥有一部手机;60.4%的患者每天使用这些设备的时间≥2小时,10.1%的患者每天使用这些设备的时间>5小时。电子设备的常用用途是听音乐(96.7%)、拍照(85.4%)、发短信(84.8%)和学术活动(84.5%)。中度和重度无恐惧症患病率分别为49.8%和34.2%。严重无恐惧症的患病率在女生(p<0.001)、13年级学生(p=0.036)、公立学校学生(p=0.002)、僧伽罗中等学生(p=0.017)和理科学生(p=0.024)中显著较高。结论:斯里兰卡科伦坡市GCE A/L学生中,99.7%的学生定期使用通讯设备。中度和重度无恐惧症患病率分别为49.8%和34.2%。
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引用次数: 0
Slow verses rapid advancement of enteral feed in preterm neonates of 28-34 weeks of gestational age with abnormal antenatal umbilical artery Doppler: A randomised controlled trial 对孕龄 28-34 周、产前脐动脉多普勒检查异常的早产新生儿进行慢速与快速肠内喂养对比:随机对照试验
Q4 Medicine Pub Date : 2023-12-05 DOI: 10.4038/sljch.v52i4.10638
L. Kasula, Rakesh Kotha, Alimelu Madireddy
Background: Necrotising enterocolitis (NEC) is the commonest and most serious gastrointestinal neonatal emergency. In preterm infants with evidence of abnormal Doppler flow velocities in the fetal umbilical artery, suboptimal intestinal perfusion is postulated to increase the risk of feed intolerance and NEC.Objectives: To compare the effect of slow versus rapid enteral feeding in preterm neonates with abnormal antenatal umbilical artery Doppler.Method: This is a randomised controlled trial; we randomised into a slow and a fast group; we randomised separately into subcategories based on the weight. Sample size was calculated as 82. Data analysis was done using SPSS version 23. For group comparisons of categorical data, Chi-squared test was used. If expected frequency in the contingency tables was <5 for more than 25% cells, Fisher’s exact test was used. For non-parametric continuous data Mann-Whitney test was applied. Statistical significance was kept at p<0.05 and power at 80%.Results: In neonates with slow and rapid feeding with birth weight <1250g, percentage of 2b (30% and 26.7% respectively) was more compared to other stages, whereas in group with birth weight ≥1250g rapid feeding group Ia (14.3%) was more in slow feeding group and 1a and 2a equal in rapid feeding group with no statistical significance. The mean duration of stay hospital was less in rapid feeding group in both birth strata. The sepsis percentage was more in the slow feeding group. Regarding mortality in both groups, there was no statistical difference.Conclusions: In this study the type of feeding did not affect NEC or feeding intolerance in preterm infants. Rapid feeding had a significant impact on sepsis and length of stay in preterm infants.
背景:坏死性小肠结肠炎(NEC)是最常见和最严重的新生儿胃肠道急症。在胎儿脐动脉多普勒血流速度异常的早产儿中,亚理想的肠道灌注被认为会增加饲料不耐受和NEC的风险。目的:比较慢速和快速肠内喂养对脐动脉多普勒异常早产儿的影响。方法:采用随机对照试验;我们随机分为慢速组和快速组;我们根据权重分别随机分成子类别。样本量计算为82。数据分析使用SPSS version 23。分类资料的组间比较采用卡方检验。如果超过25%的细胞在列联表中的预期频率<5,则使用Fisher精确检验。对非参数连续数据采用Mann-Whitney检验。p<0.05,功率为80%。结果:慢速和快速喂养出生体重<1250g的新生儿中,2b的比例(分别为30%和26.7%)高于其他阶段,而在出生体重≥1250g组中,快速喂养组Ia的比例(14.3%)高于慢速喂养组,快速喂养组1a和2a的比例相等,但差异无统计学意义。快速喂养组和快速喂养组的平均住院时间均较短。慢饲组脓毒症发生率较高。两组的死亡率无统计学差异。结论:在本研究中,喂养方式对早产儿NEC或喂养不耐受没有影响。快速喂养对早产儿脓毒症和住院时间有显著影响。
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引用次数: 0
Does anaemia increase the risk of acute lower respiratory tract infections in children aged 1-5 years? 贫血是否会增加 1-5 岁儿童患急性下呼吸道感染的风险?
Q4 Medicine Pub Date : 2023-12-05 DOI: 10.4038/sljch.v52i4.10581
Jayasekara Mudiyanselage Dinesh Kumara, Manori Gamage
Introduction: Anaemia is a major problem in children aged 1-5 years. Lower respiratory tract infection (LRTI) is defined as inflammation of the respiratory tract below the level of the larynx and is a common cause of admission to paediatric units in Sri Lanka. It is reported that anaemic children have a high risk of developing LRTIs.Objectives: To identify the association between anaemia and increased risk of developing LRTI in children aged 1-5 years presenting to a selected children's hospital in Sri Lanka.Method: A case-control study was conducted in all paediatric medical wards and intensive care units in Sirimavo Bandaranayake Children's Hospital, Peradeniya, from November 2022 to March 2023. Children aged 1-5 years admitted with LRTI were selected as cases. Children aged 1-5 years admitted without features of respiratory tract infection were selected as controls to match the age and sex of the cases. Data were collected from a questionnaire to parents and also from patient records. Data were analysed using SPSS version 22.Results: A total of 272 children was included in the study. Anaemia was found in 56.6% of cases and 44.9% of controls. The mean haemoglobin (Hb) levels of the cases and controls were 10.00±0.899 and 10.16±0.8032 respectively. Among cases, there were 57.4% of hypochromic-microcytic peripheral smears. Frequency of anaemia was significantly higher among cases as compared to controls (Odds ratio 1.605; CI: 1.025- 2.590, p-value= 0.045).Conclusions: The frequency of anaemia was significantly higher among cases as compared to controls. Anaemic children were 1.6 times more prone to get LRTI.
贫血是1-5岁儿童的主要问题。下呼吸道感染(LRTI)被定义为喉部以下的呼吸道炎症,是斯里兰卡儿科住院的常见原因。据报道,贫血儿童发生下呼吸道感染的风险很高。目的:确定在斯里兰卡某儿童医院就诊的1-5岁儿童贫血与下呼吸道感染风险增加之间的关系。方法:于2022年11月至2023年3月在Peradeniya市Sirimavo Bandaranayake儿童医院的所有儿科病房和重症监护病房进行病例对照研究。选取1 ~ 5岁入院的LRTI患儿作为病例。选取1 ~ 5岁入院无呼吸道感染特征的患儿作为对照,与病例的年龄、性别相匹配。数据收集自对家长的问卷调查和患者记录。数据分析使用SPSS version 22。结果:本研究共纳入272名儿童。贫血发生率为56.6%,对照组为44.9%。两组患者血红蛋白(Hb)均值分别为10.00±0.899和10.16±0.8032。在这些病例中,有57.4%的低色素小细胞外周涂片。与对照组相比,病例中贫血的发生率显著升高(优势比1.605;CI: 1.025 ~ 2.590, p值= 0.045)。结论:与对照组相比,病例中贫血的频率明显较高。贫血儿童患下呼吸道感染的几率是正常人的1.6倍。
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引用次数: 0
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Sri Lanka Journal of Child Health
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