中国血吸虫病防治杂志最新文献_第4页

[Spatiotemporal distribution of newly diagnosed echinococcosis patients in Qinghai Province from 2016 to 2022]. 2016 - 2022年青海省新发棘球蚴病患者时空分布分析

Q3 Medicine

中国血吸虫病防治杂志

Pub Date : 2024-08-20 DOI: 10.16250/j.32.1374.2024058

X Cui, X Ma, N Liu, J Liu, W Lei, S Wu, X Qin, C Gong, X Mo, S Yang, T Zhang, L Cao

Objective: To investigate the spatiotemporal distribution characteristics and potential influencing factors of newly diagnosed echinococcosis cases in Qinghai Province from 2016 to 2022, so as to provide insights into the formulation of the echinococcosis control strategy in Qinghai Province.Methods: The number of individuals screened for echinococcosis, number of newly diagnosed echinococcosis cases, number of registered dogs and number of stray dogs were captured from the annual reports of echinococcosis control program in Qinghai Province from 2016 to 2022, and the detection of newly diagnosed echinococcosis cases was calculated. The number of populations, precipitation, temperature, wind speed, sunshine hours, average altitude, number of year-end cattle stock, number of year-end sheep stock, gross domestic product (GDP) per capita, and number of village health centers in each county (district) of Qinghai Province were captured from the Qinghai Provincial Statistical Yearbook, and county-level electronic maps in Qinghai Province were downloaded from the National Platform for Common Geospatial Information Services. The software ArcGIS 10.8 was used to map the distribution of newly diagnosed echinococcosis cases in Qinghai Province, and the spatial autocorrelation analysis of newly diagnosed echinococcosis cases was performed. In addition, the spacetime scan analyses of number of individuals screened for echinococcosis, number of newly diagnosed echinococcosis cases and geographical coordinates in Qinghai Province were performed with the software SaTScan 10.1.2, and the spatial stratified heterogeneity of the detection of newly diagnosed echinococcosis cases was investigated with the software GeoDetector.Results: A total of 6 569 426 residents were screened for echinococcosis in Qinghai Province from 2016 to 2022, and 5 924 newly diagnosed echinococcosis cases were found. The detection of newly diagnosed echinococcosis cases appeared a tendency towards a decline over years from 2016 to 2022 (χ2 = 11.107, P < 0.01), with the highest detection in Guoluo Tibetan Autonomous Prefecture in 2017 (82.12/105). There were spatial clusters in the detection of newly diagnosed echinococcosis cases in Qinghai Province from 2016 to 2018 (Moran's I = 0.34 to 0.65, all Z values > 1.96, all P values < 0.05), and the distribution of newly diagnosed echinococcosis cases appeared random distribution from 2019 to 2022 (Moran's I = -0.09 to 0.04, all Z values < 1.96, all P values > 0.05). Local spatial autocorrelation analysis showed high-high clusters and low-low clusters in the detection of new diagnosed echinococcosis cases in Qinghai Province from 2016 to 2022, and space-time scan analysis showed that the first most likely cluster areas of newly diagnosed echinococcosis cases in Qinghai Province from 2016 to 2022 were ma

目的：了解青海省2016 - 2022年棘球蚴病新发病例的时空分布特征及潜在影响因素，为青海省棘球蚴病防治策略的制定提供参考。方法：采集青海省2016 - 2022年棘球蚴病防治项目年度报告中棘球蚴病筛查人数、新诊断棘球蚴病病例数、登记犬数和流浪犬数，计算新诊断棘球蚴病的检出率。从《青海省统计年鉴》中获取青海省各县（区）人口数量、降水量、气温、风速、日照时数、平均海拔、年末牛存栏数、年末羊存栏数、人均国内生产总值（GDP）、村卫生院数，并从国家公共地理空间信息服务平台下载青海省县级电子地图。采用ArcGIS 10.8软件绘制青海省新诊断棘球蚴病病例分布图，并对新诊断棘球蚴病病例进行空间自相关分析。此外，利用SaTScan 10.1.2软件对青海省棘球蚴病筛查人数、新诊断棘球蚴病病例数和地理坐标进行时空扫描分析，并利用GeoDetector软件对新诊断棘球蚴病病例检测的空间分层异质性进行分析。结果：2016 - 2022年青海省共筛查居民棘球蚴病6 569 426例，发现新诊断棘球蚴病5 924例。2016 - 2022年棘球蚴病新诊断率呈逐年下降趋势（χ2 = 11.107, P < 0.01）， 2017年果洛藏族自治州棘球蚴病新诊断率最高（82.12/105）。2016 - 2018年青海省新诊断棘球蚴病病例检测呈空间聚类分布（Moran’s I = 0.34 ~ 0.65， Z值均为> 1.96，P值均< 0.05），2019 - 2022年棘球蚴病新诊断病例分布呈随机分布（Moran’s I = -0.09 ~ 0.04， Z值均< 1.96，P值均为> 0.05）。局部空间自相关分析显示，2016 - 2022年青海省新发棘球蚴病病例检测呈高聚类和低聚类，时空扫描分析显示，2016 - 2022年青海省新发棘球蚴病病例第一可能聚集区主要分布在玉树藏族自治州和果洛藏族自治州。基于geodetection的青海省新发棘球蚴病病例空间分层异质性驱动因素分析表明，平均海拔、村卫生院数、牛羊存畜量、人均GDP、年平均日照时数、年平均气温对新发棘球蚴病病例的空间分布具有较强的解释力，其q值分别为0.630、0.610、0.600、0.590、0.588。分别为0.537和0.526。结论：2016 - 2022年青海省棘球蚴病新发病例检出率呈下降趋势，呈空间聚类。为进一步控制该病，需要在新诊断棘球蚴病病例聚集地区采取有针对性的控制措施。

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引用次数: 0

[Risk factors of visceral leishmaniasis in the world: a review]. [全球内脏利什曼病的风险因素：综述]。

Q3 Medicine

中国血吸虫病防治杂志

Pub Date : 2024-08-06 DOI: 10.16250/j.32.1374.2024079

X Chen, Y Shi, S Zhou, M Geng, H Tu, J Song, C Zheng, J Sun

Visceral leishmaniasis is a zoonotic parasitic disease caused by viscerotropic Leishmania species and transmitted by bites of infected phlebotomine sandflies, which is predominantly prevalent in the Indian subcontinent, eastern Africa and South America. Currently, visceral leishmaniasis is the second most fatal parasitic disease in the world. Because of climate changes, urban development and individual conditions, there are changes in the density of visceral leishmaniasis vector sandflies and the likelihood of contact with humans, resulting in a visceral leishmaniasis transmission risk. The review summarizes natural, social and biological factors affecting the transmission of visceral leishmaniasis, so as to provide insights into formulation of targeted control measures for visceral leishmaniasis.

内脏利什曼病是一种人畜共患的寄生虫病，由内脏利什曼原虫引起，通过被感染的噬血沙蝇叮咬传播，主要流行于印度次大陆、非洲东部和南美洲。目前，内脏利什曼病是世界上第二大致命寄生虫病。由于气候变化、城市发展和个人条件等原因，内脏利什曼病病媒沙蝇的密度和与人类接触的可能性发生了变化，从而导致了内脏利什曼病传播风险。本综述总结了影响内脏利什曼病传播的自然、社会和生物因素，为制定有针对性的内脏利什曼病控制措施提供启示。

引用次数: 0

[Genetic polymorphisms of common sandflies in selected areas of Henan Province based on DNA barcoding]. [基于 DNA 条形码的河南省部分地区常见沙蝇的遗传多态性]。

Q3 Medicine

中国血吸虫病防治杂志

Pub Date : 2024-08-05 DOI: 10.16250/j.32.1374.2024036

D Wang, Z He, C Yang, D Lu, Y Sun, Y Kou, D Qian, H Zhang, Y Liu

Objective: To characterize the species of common sandflies in Henan Province using DNA barcoding with cytochrome c oxidase subunit I (COI) gene as the molecular marker, and to analyze the genetic polymorphisms of sandflies, so as to provide insights into visceral leishmaniasis prevention and control in Henan Province.Methods: Sandfly specimens were sampled from 13 sandflies surveillance sites from 2021 to 2023 in Anyang City, Zhengzhou, Luoyang and Xuchang cities (Zhengzhou-Luoyang-Xuchang areas) where visceral leishmaniasis cases were reported and in Jiaozuo and Xinxiang cities (Jiaozuo-Xinxiang areas) without visceral leishmaniasis cases reported. Genomic DNA was extracted from a single sandfly, and COI gene was amplified. The amplification product was subjected to bidirectional sequencing. Following sequence assembly, the species of sandflies was characterized through sequence alignment using the BLAST tool. The intra-specific and inter-specific genetic distances of sandflies were estimated among different areas using the software Mega 11, and phylogenetic trees were created. The polymorphisms of nucleotide sequences in the sandflies COI gene were estimated using the software DnaSP. The fixation index (FST) of different geographical isolates of sandflies was calculated using the Arlequin software, and the gene flow value (Nm) was used to measure the gene flow in the sandflies populations. In addition, the population genetic structure of different geographical populations of Phlebotomus chinensis was analyzed using the STRUCTURE software.Results: A total of 978 sandflies were collected from 13 sandflies surveillance sites in Zhengzhou-Luoyang-Xuchang areas, Jiaozuo-Xinxiang areas and Anyang City of Henan Province from 2021 to 2023, and 475 sandflies were randomly sampled for subsequent detections. A total of 304 Ph. chinensis, 162 Se. squamirostris and 9 Se. bailyi were identified based on molecular biological detection of the COI gene, and Se. bailyi was reported for the first time in Henan Province. The intraspecific genetic distances of sandflies were 0.000 to 0.040, and the inter-specific genetic distances ranged from 0.133 to 0.161. Phylogenetic analysis revealed that each of the three sandfly species was clustered into a clade. The genetic polymorphisms of Ph. chinensis populations varied among different areas, with the highest haplotype diversity (0.966 ± 0.007) and the greatest nucleotide diversity (0.011) in Zhengzhou-Luoyang-Xuchang areas, and the lowest haplotype diversity (0.720 ± 0.091) and nucleotide diversity (0.004) in Anyang City. The dominant haplotype of Ph. chinensis populations was Pch_Hap_2 in Anyang City and Jiaozuo-Xinxiang areas, with moderate genetic differentiation (0.05 < FST < 0.15) and frequent gene exchange (Nm value > 1)

目的以细胞色素c氧化酶亚单位I（COI）基因为分子标记，采用DNA条形码技术，对河南省常见沙蝇的种类进行鉴定，并分析沙蝇的遗传多态性，为河南省内脏利什曼病的防控提供参考：方法：从2021年至2023年，在有内脏利什曼病病例报告的安阳市、郑州市、洛阳市和许昌市（郑州-洛阳-许昌地区）以及无内脏利什曼病病例报告的焦作市和新乡市（焦作-新乡地区）的13个沙蝇监测点采集沙蝇标本。从一只沙蝇身上提取基因组 DNA 并扩增 COI 基因。对扩增产物进行双向测序。序列组装后，使用 BLAST 工具进行序列比对，确定了沙蝇的种类。利用软件 Mega 11 估计了不同地区沙蝇的种内和种间遗传距离，并建立了系统发生树。利用 DnaSP 软件估算了沙蝇 COI 基因核苷酸序列的多态性。利用 Arlequin 软件计算了不同地域沙蝇分离株的固定指数（FST），并用基因流值（Nm）来衡量沙蝇种群的基因流。此外，还利用 STRUCTURE 软件分析了不同地理种群的沙蝇种群遗传结构：2021-2023年，在河南省郑州-洛阳-许昌地区、焦作-新乡地区和安阳市的13个沙蝇监测点共采集沙蝇978只，随机抽样475只进行后续检测。通过COI基因的分子生物学检测，共鉴定出304只Ph. chinensis、162只Se. squamirostris和9只Se. bailyi，其中Se. bailyi为河南省首次报道。沙蝇种内遗传距离为0.000～0.040，种间遗传距离为0.133～0.161。系统进化分析表明，这三种沙蝇各自聚为一个支系。郑州-洛阳-许昌地区的单倍型多样性（0.966±0.007）和核苷酸多样性（0.011）最高，安阳市的单倍型多样性（0.720±0.091）和核苷酸多样性（0.004）最低。在安阳市和焦作-新乡地区，箭竹种群的优势单倍型为Pch_Hap_2，遗传分化程度中等（0.05＜FST＜0.15），基因交换频繁（Nm值＞1）；在安阳市和焦作-新乡地区，箭竹种群的优势单倍型为Pch_Hap_2，遗传分化程度中等（0.05＜FST＜0.15），基因交换频繁（Nm值＞1）。种群遗传结构分析表明，在安阳市和焦作-新乡地区，Ph. chinensis种群的优势成分为K5。郑州-洛阳-许昌地区的箭竹种群没有发现明显的优势单倍型，与安阳市和焦作-新乡地区的箭竹种群遗传分化程度很高（FST>0.25），基因交换很少（Nm值<1），优势成分为K3。此外，这三个地区的鳞蟾种群之间的遗传多态性水平无显著差异：结论：河南省有Ph. chinensis、Se. squamirostris和Se. bailyi三个种群，其中Se. bailyi是首次在河南省发现。河南省不同地区的P. chinensis种群之间存在不同程度的遗传分化和基因交换。

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引用次数: 0

[Prevalence of canine Leishmania infections in Xin'an County, Luoyang City in 2020]. [2020年洛阳市新安县犬利什曼原虫感染流行情况]。

Q3 Medicine

中国血吸虫病防治杂志

Pub Date : 2024-08-05 DOI: 10.16250/j.32.1374.2024034

R Cheng, Y Sun, C Yang, X Zhu

Objective: To investigate the prevalence of canine Leishmania infections in villages endemic for visceral leishmaniasis in Xin'an County, Luoyang City, so as to provide insights into visceral leishmaniasis prevention and control.

Methods: All dogs were captured from Huzhanggou Village, Xin'an County, Luoyang City in August 2020, where local cases with visceral leishmaniasis lived. The basic characteristics of dogs were collected, and venous blood was collected via the ear or neck veins of dogs. The serum anti-Leishmania antibody was detected using the rk39 immunochromatographic test and Leishmania nucleic acid was detected using PCR assay, and the prevalence of Leishmania infection was estimated in dogs.

Results: A total of 133 domestic dogs were captured from Huzhanggou Village, with a median age of 18.0 (28.5) months. The sero-prevalence of anti-Leishmania antibody was 24.81% (33/133) and the prevalence of a positive PCR assay was 14.29% (19/133) in dogs. The median ages of Leishmania-infected and uninfected dogs were 24.0 (36.0) months and 12.0 (18.0) months, respectively (U = 872.000, P = 0.000), and the prevalence of Leishmania infection was 55.56% (5/9) in "mangy dogs" and 24.19% (30/124) in asymptomatic dogs (χ² = 2.793, P = 0.095).

Conclusions: There are a large number of asymptomatic dogs with Leishmania infections in Xin'an County, Luoyang City, with a high transmission risk of visceral leishmaniasis. Timely prevention and control measures are required to control the spread of visceral leishmaniasis.

目的调查洛阳市新安县内脏利什曼病流行村的犬利什曼病感染率，为内脏利什曼病防控提供参考：所有犬只均于2020年8月在洛阳市新安县胡张沟村捕获，当地有内脏利什曼病病例。采集犬的基本特征，经耳静脉或颈部静脉采集静脉血。采用 rk39 免疫层析法检测血清抗利什曼病抗体，采用 PCR 法检测利什曼病核酸，并估计犬的利什曼病感染率：结果：从胡张沟村共捕获 133 只家犬，中位年龄为 18.0（28.5）个月。狗的抗利什曼原虫抗体血清阳性率为 24.81%（33/133），PCR 检测阳性率为 14.29%（19/133）。利什曼原虫感染犬和未感染犬的中位年龄分别为 24.0 (36.0) 个月和 12.0 (18.0) 个月（U = 872.000，P = 0.000），"癞皮狗 "的利什曼原虫感染率为 55.56%（5/9），无症状犬的感染率为 24.19%（30/124）（χ2 = 2.793，P = 0.095）：洛阳市新安县有大量无症状犬感染利什曼病，内脏利什曼病传播风险高。需要及时采取防控措施，控制内脏利什曼病的传播。

{"title":"[Prevalence of canine Leishmania infections in Xin'an County, Luoyang City in 2020].","authors":"R Cheng, Y Sun, C Yang, X Zhu","doi":"10.16250/j.32.1374.2024034","DOIUrl":"https://doi.org/10.16250/j.32.1374.2024034","url":null,"abstract":"Objective: To investigate the prevalence of canine Leishmania infections in villages endemic for visceral leishmaniasis in Xin'an County, Luoyang City, so as to provide insights into visceral leishmaniasis prevention and control.Methods: All dogs were captured from Huzhanggou Village, Xin'an County, Luoyang City in August 2020, where local cases with visceral leishmaniasis lived. The basic characteristics of dogs were collected, and venous blood was collected via the ear or neck veins of dogs. The serum anti-Leishmania antibody was detected using the rk39 immunochromatographic test and Leishmania nucleic acid was detected using PCR assay, and the prevalence of Leishmania infection was estimated in dogs.Results: A total of 133 domestic dogs were captured from Huzhanggou Village, with a median age of 18.0 (28.5) months. The sero-prevalence of anti-Leishmania antibody was 24.81% (33/133) and the prevalence of a positive PCR assay was 14.29% (19/133) in dogs. The median ages of Leishmania-infected and uninfected dogs were 24.0 (36.0) months and 12.0 (18.0) months, respectively (U = 872.000, P = 0.000), and the prevalence of Leishmania infection was 55.56% (5/9) in \"mangy dogs\" and 24.19% (30/124) in asymptomatic dogs (χ2 = 2.793, P = 0.095).Conclusions: There are a large number of asymptomatic dogs with Leishmania infections in Xin'an County, Luoyang City, with a high transmission risk of visceral leishmaniasis. Timely prevention and control measures are required to control the spread of visceral leishmaniasis.","PeriodicalId":38874,"journal":{"name":"中国血吸虫病防治杂志","volume":"36 4","pages":"399-402"},"PeriodicalIF":0.0,"publicationDate":"2024-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142355900","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Distribution and seasonal fluctuation of visceral leishmaniasis vectors sandflie in Lüliang City of Shanxi Province in 2023]. [2023 年山西省吕梁市内脏利什曼病病媒沙蝇的分布及季节性波动]。

Q3 Medicine

中国血吸虫病防治杂志

Pub Date : 2024-07-31 DOI: 10.16250/j.32.1374.2024025

Y Wang, Y Jia, Y Liang, P Hao, X Tian, W Feng, X Dong, C Wang, Y Zhang, H Chen

Objective: To investigate the distribution and seasonal fluctuations of visceral leishmaniasis vectors sandflies in Lüliang City, Shanxi Province, so as to provide insights into assessment of the visceral leishmaniasis transmission risk and formulation of visceral leishmaniasis control measures.

Methods: A total of 12 natural villages were sampled from Shilou County, Lishi District, Lanxian County, Linxian County and Wenshui County in Lüliang City, Shanxi Province from June to September, 2023, and sandflies were captured using light traps from 7 breeding habitats, including farmers' houses, sheep pens, cattle pens, chicken coops, pig pens, mule and horse pens, and loess-cave dwellings. Following morphological identification of the sandfly species, the distribution of sandflies and the seasonal fluctuations of the sandfly density were analyzed. In addition, the Leishmania was detected in sandflies using a real-time fluorescence quantitative PCR assay.

Results: A total of 2 831 sandflies were captured with 156 light traps in Lüliang City from June to September, 2023, including 2 638 female sandflies (93.18%) and 193 male sandflies (6.82%), and the average density was 16.91 sandflies/(light-night). The seasonal fluctuations of the sandfly density all appeared a unimodal distribution in all survey sites, and the sandfly density peaked in July and then declined rapidly. Among all types of breeding habitats, the greatest sandfly density was found in sheep pens [39.04 sandflies/(light-night)]. In addition, 4.08% (2/49) of the sandfly samples were tested positive for Leishmania nucleic acid as revealed by the real-time fluorescence quantitative PCR assay.

Conclusions: Sandflies were widely distributed in Lüliang City, Shanxi Province in 2023, and the peak of the sandfly density was observed in July, which had a visceral leishmaniasis transmission risk. Intensified surveillance of visceral leishmaniasis and sandfly vectors is required and targeted vector control is recommended.

目的调查山西省吕梁市内脏利什曼病病媒沙蝇的分布及季节性波动情况，为评估内脏利什曼病传播风险和制定内脏利什曼病防控措施提供依据：方法：2023年6月至9月，在山西省吕梁市石楼县、离石区、岚县、临县和文水县共12个自然村采样，在农户房屋、羊圈、牛圈、鸡舍、猪圈、骡马圈、黄土窑洞等7个孳生栖息地用光诱捕器捕捉沙蝇。在对沙蝇种类进行形态鉴定后，分析了沙蝇的分布情况和沙蝇密度的季节性波动。此外，还利用实时荧光定量 PCR 法检测了沙蝇体内的利什曼原虫：2023年6月至9月，吕梁市共使用156个灯光诱捕器捕获了2 831只沙蝇，其中雌沙蝇2 638只（占93.18%），雄沙蝇193只（占6.82%），平均密度为16.91只/（灯-夜）。在所有调查地点，沙蝇密度的季节波动均呈单峰分布，沙蝇密度在 7 月达到峰值，随后迅速下降。在所有类型的繁殖生境中，羊圈的沙蝇密度最大[39.04只/（光-夜）]。此外，实时荧光定量 PCR 检测显示，4.08%（2/49）的沙蝇样本利什曼原虫核酸检测呈阳性：2023年山西省吕梁市沙蝇分布广泛，7月为沙蝇密度高峰期，存在内脏利什曼病传播风险。需要加强对内脏利什曼病和沙蝇病媒的监测，并建议进行有针对性的病媒控制。

{"title":"[Distribution and seasonal fluctuation of visceral leishmaniasis vectors sandflie in Lüliang City of Shanxi Province in 2023].","authors":"Y Wang, Y Jia, Y Liang, P Hao, X Tian, W Feng, X Dong, C Wang, Y Zhang, H Chen","doi":"10.16250/j.32.1374.2024025","DOIUrl":"https://doi.org/10.16250/j.32.1374.2024025","url":null,"abstract":"Objective: To investigate the distribution and seasonal fluctuations of visceral leishmaniasis vectors sandflies in Lüliang City, Shanxi Province, so as to provide insights into assessment of the visceral leishmaniasis transmission risk and formulation of visceral leishmaniasis control measures.Methods: A total of 12 natural villages were sampled from Shilou County, Lishi District, Lanxian County, Linxian County and Wenshui County in Lüliang City, Shanxi Province from June to September, 2023, and sandflies were captured using light traps from 7 breeding habitats, including farmers' houses, sheep pens, cattle pens, chicken coops, pig pens, mule and horse pens, and loess-cave dwellings. Following morphological identification of the sandfly species, the distribution of sandflies and the seasonal fluctuations of the sandfly density were analyzed. In addition, the Leishmania was detected in sandflies using a real-time fluorescence quantitative PCR assay.Results: A total of 2 831 sandflies were captured with 156 light traps in Lüliang City from June to September, 2023, including 2 638 female sandflies (93.18%) and 193 male sandflies (6.82%), and the average density was 16.91 sandflies/(light-night). The seasonal fluctuations of the sandfly density all appeared a unimodal distribution in all survey sites, and the sandfly density peaked in July and then declined rapidly. Among all types of breeding habitats, the greatest sandfly density was found in sheep pens [39.04 sandflies/(light-night)]. In addition, 4.08% (2/49) of the sandfly samples were tested positive for Leishmania nucleic acid as revealed by the real-time fluorescence quantitative PCR assay.Conclusions: Sandflies were widely distributed in Lüliang City, Shanxi Province in 2023, and the peak of the sandfly density was observed in July, which had a visceral leishmaniasis transmission risk. Intensified surveillance of visceral leishmaniasis and sandfly vectors is required and targeted vector control is recommended.","PeriodicalId":38874,"journal":{"name":"中国血吸虫病防治杂志","volume":"36 4","pages":"403-406"},"PeriodicalIF":0.0,"publicationDate":"2024-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142355889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Epidemiological features of visceral leishmaniasis cases in Henan Province from 2021 to 2023]. [2021-2023 年河南省内脏利什曼病病例流行病学特征]。

Q3 Medicine

中国血吸虫病防治杂志

Pub Date : 2024-07-30 DOI: 10.16250/j.32.1374.2024024

C Yang, D Wang, D Lu, Z He, P Ji, D Qian, Y Liu, Y Kou, S Li, R Zhou, Y Deng, H Zhang

Objective: To analyze the characteristics of visceral leishmaniasis cases in Henan Province, so as to provide insights into formulation of the visceral leishmaniasis control srtrategy.

Methods: All epidemiological data of reported visceral leishmaniasis cases in Henan Province from 2021 to 2023 were retrieved from the National Notifiable Disease Report Information Management System of Chinese Center for Disease Control and Prevention, and the epidemiological features and diagnosis of visceral leishmaniasis cases were descriptively analyzed.

Results: A total of 93 visceral leishmaniasis cases were reported in Henan Province from 2021 to 2023, with a male to female ratio of 2.58∶1, and including 2 imported cases from other provinces and 91 local cases. The number of visceral leishmaniasis cases peaked during the period between March and May, and between July and October. The reported visceral leishmaniasis cases had ages of 7 months to 74 years, with the largest number of cases found at ages of 0 to 9 years (26 cases, 27.96%), followed by at ages of 60 to 70 years (24 cases, 25.81%). Farmer (47 cases, 50.54%) and diaspora children (19 cases, 20.43%) were predominant occupations, and 91 local visceral leishmaniasis cases were found in 6 cities of Zhengzhou, Luoyang, Anyang, Hebi, Sanmenxia and Xuchang. The median duration from onset of visceral leishmaniasis to diagnosis was 20 days, and there were 25.81% (24/93) cases with 10 days and less duration from onset to diagnosis, 38.71% (36/93) cases receiving diagnosis at 11 to 30 days following onset, and 35.48% (33/93) cases receiving diagnosis for more than 30 days following onset. All cases were predominantly diagnosed in province- (60.00%) and city-level (28.89%) medical institutions.

Conclusions: The number of visceral leishmaniasis is on the rise in Henan Province, with a gradually expanding coverage. Intensified monitoring of visceral leishmaniasis cases, dogs, and vectors, dog management, sandflies control and improved individual protection are recommended to prevent the spread of visceral leishmaniasis.

摘要分析河南省内脏利什曼病病例特征，为制定内脏利什曼病控制策略提供参考：方法：从中国疾病预防控制中心 "全国报告病例信息管理系统 "中调取河南省2021-2023年报告的所有内脏利什曼病病例的流行病学资料，对内脏利什曼病病例的流行病学特征和诊断进行描述性分析：结果：2021-2023年河南省共报告内脏利什曼病病例93例，男女比例为2.58∶1，其中外省输入病例2例，本地病例91例。内脏利什曼病病例数在 3 月至 5 月和 7 月至 10 月期间达到高峰。报告的内脏利什曼病病例年龄在 7 个月至 74 岁之间，其中 0 至 9 岁的病例最多（26 例，占 27.96%），其次是 60 至 70 岁（24 例，占 25.81%）。农民（47 例，50.54%）和散居儿童（19 例，20.43%）是主要职业，91 例本地内脏利什曼病病例分布在郑州、洛阳、安阳、鹤壁、三门峡和许昌 6 个城市。内脏利什曼病从发病到确诊的时间中位数为 20 天，其中 25.81%（24/93）的病例从发病到确诊的时间在 10 天及以下，38.71%（36/93）的病例在发病后 11-30 天得到确诊，35.48%（33/93）的病例在发病后 30 天以上得到确诊。所有病例主要在省级（60.00%）和市级（28.89%）医疗机构确诊：结论：河南省内脏利什曼病发病人数呈上升趋势，发病范围逐渐扩大。建议加强对内脏利什曼病病例、犬只和病媒的监测、犬只管理、沙蝇控制和加强个人防护，以防止内脏利什曼病的传播。

{"title":"[Epidemiological features of visceral leishmaniasis cases in Henan Province from 2021 to 2023].","authors":"C Yang, D Wang, D Lu, Z He, P Ji, D Qian, Y Liu, Y Kou, S Li, R Zhou, Y Deng, H Zhang","doi":"10.16250/j.32.1374.2024024","DOIUrl":"https://doi.org/10.16250/j.32.1374.2024024","url":null,"abstract":"Objective: To analyze the characteristics of visceral leishmaniasis cases in Henan Province, so as to provide insights into formulation of the visceral leishmaniasis control srtrategy.Methods: All epidemiological data of reported visceral leishmaniasis cases in Henan Province from 2021 to 2023 were retrieved from the National Notifiable Disease Report Information Management System of Chinese Center for Disease Control and Prevention, and the epidemiological features and diagnosis of visceral leishmaniasis cases were descriptively analyzed.Results: A total of 93 visceral leishmaniasis cases were reported in Henan Province from 2021 to 2023, with a male to female ratio of 2.58∶1, and including 2 imported cases from other provinces and 91 local cases. The number of visceral leishmaniasis cases peaked during the period between March and May, and between July and October. The reported visceral leishmaniasis cases had ages of 7 months to 74 years, with the largest number of cases found at ages of 0 to 9 years (26 cases, 27.96%), followed by at ages of 60 to 70 years (24 cases, 25.81%). Farmer (47 cases, 50.54%) and diaspora children (19 cases, 20.43%) were predominant occupations, and 91 local visceral leishmaniasis cases were found in 6 cities of Zhengzhou, Luoyang, Anyang, Hebi, Sanmenxia and Xuchang. The median duration from onset of visceral leishmaniasis to diagnosis was 20 days, and there were 25.81% (24/93) cases with 10 days and less duration from onset to diagnosis, 38.71% (36/93) cases receiving diagnosis at 11 to 30 days following onset, and 35.48% (33/93) cases receiving diagnosis for more than 30 days following onset. All cases were predominantly diagnosed in province- (60.00%) and city-level (28.89%) medical institutions.Conclusions: The number of visceral leishmaniasis is on the rise in Henan Province, with a gradually expanding coverage. Intensified monitoring of visceral leishmaniasis cases, dogs, and vectors, dog management, sandflies control and improved individual protection are recommended to prevent the spread of visceral leishmaniasis.","PeriodicalId":38874,"journal":{"name":"中国血吸虫病防治杂志","volume":"36 4","pages":"393-398"},"PeriodicalIF":0.0,"publicationDate":"2024-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142355894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Distribution and seasonal fluctuation of visceral leishmaniasis vectors sandflies in Henan Province in 2023]. [2023 年河南省内脏利什曼病病媒沙蝇的分布和季节性波动]。

Q3 Medicine

中国血吸虫病防治杂志

Pub Date : 2024-07-30 DOI: 10.16250/j.32.1374.2024030

Z He, D Wang, Y Kou, C Yang, Y Sun, P Ji, T Jiang, D Lu, D Qian, H Zhang, Y Liu

Objective: To investigate the geographical distribution and seasonal fluctuations of visceral leishmaniasis vectors sandflies in Henan Province in 2023, so as to provide insights into the prevention and control of visceral leishmaniasis vectors.

Methods: A total of 23 counties (districts) were sampled from 18 cities of Henan Province from May to September, 2023 as sandfly surveillance sites, and sandflies were captured using human capture and light trapping methods. Following morphological identification, the changes in the sandfly density were calculated at different months and in different breeding habitats.

Results: A total of 406 light traps were set at sandfly surveillance sites in Henan Province from May to September, 2023, and a total of 3 137 female sandlies were captured, with an average density of 7.73 sandlies/(light·night). A total of 1 494 Phlebotomus chinensis sandflies were captured, including 1 222 female sandflies, with an average density of 3.01 sandflies/(light·night), and the highest density of P. chinensis was found in Gongyi City [17.00 sandflies/(light·night)]. A total of 5 544 sandflies were captured using the human capture method, including 230 P. chinensis, and the density of P. chinensis appeared a unimodal distribution, with a peak in early July [5.81 sandflies/(light·night)]. Among different breeding habitats, the highest P. chinensis density was detected in pigpens [4.50 sandflies/(light·night)].

Conclusions: P. chinensis was predominantly distributed in hilly areas of northern and central-western Henan Province in 2023, and the sandfly density appeared a unimodal distribution. Intensified monitoring of visceral leishmaniasis vectors is recommended.

目的调查2023年河南省内脏利什曼病病媒沙蝇的地理分布和季节性波动，为内脏利什曼病病媒的防控提供参考：方法：2023年5月至9月，在河南省18个地市共抽取23个县（区）作为沙蝇监测点，采用人捕法和灯光诱捕法捕获沙蝇。经形态鉴定后，计算不同月份、不同繁殖生境的沙蝇密度变化：2023年5月至9月，在河南省沙蝇监测点共设置了406个灯光诱捕器，共捕获雌性沙蝇3 137只，平均密度为7.73只/（灯-夜）。巩义市沙蝇密度最高[17.00只/（灯-夜）]。用人工捕捉法共捕获沙蝇5 544只，其中有沙蝇230只，沙蝇密度呈单峰分布，峰值出现在7月上旬[5.81只/（灯-夜）]。在不同的繁殖生境中，猪圈的沙蝇密度最高[4.50 沙蝇/（光-夜）]：结论：2023 年，沙蝇主要分布在河南省北部和中西部丘陵地区，沙蝇密度呈单峰分布。建议加强对内脏利什曼病病媒的监测。

{"title":"[Distribution and seasonal fluctuation of visceral leishmaniasis vectors sandflies in Henan Province in 2023].","authors":"Z He, D Wang, Y Kou, C Yang, Y Sun, P Ji, T Jiang, D Lu, D Qian, H Zhang, Y Liu","doi":"10.16250/j.32.1374.2024030","DOIUrl":"https://doi.org/10.16250/j.32.1374.2024030","url":null,"abstract":"Objective: To investigate the geographical distribution and seasonal fluctuations of visceral leishmaniasis vectors sandflies in Henan Province in 2023, so as to provide insights into the prevention and control of visceral leishmaniasis vectors.Methods: A total of 23 counties (districts) were sampled from 18 cities of Henan Province from May to September, 2023 as sandfly surveillance sites, and sandflies were captured using human capture and light trapping methods. Following morphological identification, the changes in the sandfly density were calculated at different months and in different breeding habitats.Results: A total of 406 light traps were set at sandfly surveillance sites in Henan Province from May to September, 2023, and a total of 3 137 female sandlies were captured, with an average density of 7.73 sandlies/(light·night). A total of 1 494 Phlebotomus chinensis sandflies were captured, including 1 222 female sandflies, with an average density of 3.01 sandflies/(light·night), and the highest density of P. chinensis was found in Gongyi City [17.00 sandflies/(light·night)]. A total of 5 544 sandflies were captured using the human capture method, including 230 P. chinensis, and the density of P. chinensis appeared a unimodal distribution, with a peak in early July [5.81 sandflies/(light·night)]. Among different breeding habitats, the highest P. chinensis density was detected in pigpens [4.50 sandflies/(light·night)].Conclusions: P. chinensis was predominantly distributed in hilly areas of northern and central-western Henan Province in 2023, and the sandfly density appeared a unimodal distribution. Intensified monitoring of visceral leishmaniasis vectors is recommended.","PeriodicalId":38874,"journal":{"name":"中国血吸虫病防治杂志","volume":"36 4","pages":"346-351"},"PeriodicalIF":0.0,"publicationDate":"2024-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142355890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Spatiotemporal clustering and hot spot analysis of visceral leishmaniasis in Gansu Province from 1993 to 2023]. [1993-2023年甘肃省内脏利什曼病时空聚类与热点分析]。

Q3 Medicine

中国血吸虫病防治杂志

Pub Date : 2024-07-29 DOI: 10.16250/j.32.1374.2024056

D Yu, A He, Y Feng, G Yang, C Yang, F Li

Objective: To investigate the spatiotemporal clustering characteristics of the reported incidence of visceral leishmaniasis (VL) in Gansu Province from 1993 to 2023, so as to provide insights into the containment of VL and prevention of VL recurrence.

Methods: County (district)-level epidemical data of VL in Gansu Province from 1993 to 2023 were collected, and the geographical information database of reported VL incidence in Gansu Province was created according to the county-level administrative code and electronic maps in Gansu Province. In addition, the spatial autocorrelation analysis and hot spot analysis of the reported VL incidence were performed in Gansu Province using the software ArcGIS 10.8.

Results: A total of 2 597 VL cases were reported in Gansu Province from 1993 to 2023, with an annual average incidence rate of 3.036/10⁵. Spatial autocorrelation analysis showed spatial clustering of the reported VL incidence in Gansu Province (Moran's I = 0.605, Z = 5.240, P < 0.001), appearing high-high clustering features (Getis-Ord G = 0.080, Z = 4.137, P < 0.001), and high-high clustering of the reported incidence of VL was identified in Diebu County, Tanchang County, Zhouqu County and Wenxian County. Hot spot analysis showed hot-spot areas of the reported VL incidence in Tanchang County, Zhouqu County, Wudu District and Wenxian County along the Bailong River basins and cold-spot areas in Qin'an County and Gangu County.

Conclusions: There was spatial clustering and hot spots of the reported VL incidence in Gansu Province from 1993 to 2023. Intensified surveillance and control is required to prevent the spread of VL.

目的研究1993-2023年甘肃省内脏利什曼病（VL）报告发病率的时空聚类特征，为遏制VL、预防VL复发提供启示：方法：收集 1993-2023 年甘肃省县（区）级 VL 流行病学数据，根据甘肃省县级行政区划代码和电子地图，建立甘肃省 VL 报告发病率地理信息数据库。此外，还利用 ArcGIS 10.8 软件对甘肃省报告的 VL 发病情况进行了空间自相关分析和热点分析：1993-2023年甘肃省共报告VL病例2 597例，年平均发病率为3.036/105。空间自相关分析表明，甘肃省报告的VL发病率存在空间聚类（Moran's I = 0.605, Z = 5.240, P < 0.001），出现高聚类特征（Getis-Ord G = 0.080, Z = 4.137, P < 0.001），迭部县、宕昌县、舟曲县和文县报告的VL发病率出现高聚类。热点分析显示，白龙江流域沿岸的宕昌县、舟曲县、武都区和文县为VL报告发病的热点地区，秦安县和甘谷县为冷点地区：结论：1993 年至 2023 年期间，甘肃省报告的 VL 发病率存在空间聚集和热点现象。需要加强监测和控制，以防止 VL 的传播。

{"title":"[Spatiotemporal clustering and hot spot analysis of visceral leishmaniasis in Gansu Province from 1993 to 2023].","authors":"D Yu, A He, Y Feng, G Yang, C Yang, F Li","doi":"10.16250/j.32.1374.2024056","DOIUrl":"https://doi.org/10.16250/j.32.1374.2024056","url":null,"abstract":"Objective: To investigate the spatiotemporal clustering characteristics of the reported incidence of visceral leishmaniasis (VL) in Gansu Province from 1993 to 2023, so as to provide insights into the containment of VL and prevention of VL recurrence.Methods: County (district)-level epidemical data of VL in Gansu Province from 1993 to 2023 were collected, and the geographical information database of reported VL incidence in Gansu Province was created according to the county-level administrative code and electronic maps in Gansu Province. In addition, the spatial autocorrelation analysis and hot spot analysis of the reported VL incidence were performed in Gansu Province using the software ArcGIS 10.8.Results: A total of 2 597 VL cases were reported in Gansu Province from 1993 to 2023, with an annual average incidence rate of 3.036/105. Spatial autocorrelation analysis showed spatial clustering of the reported VL incidence in Gansu Province (Moran's I = 0.605, Z = 5.240, P < 0.001), appearing high-high clustering features (Getis-Ord G = 0.080, Z = 4.137, P < 0.001), and high-high clustering of the reported incidence of VL was identified in Diebu County, Tanchang County, Zhouqu County and Wenxian County. Hot spot analysis showed hot-spot areas of the reported VL incidence in Tanchang County, Zhouqu County, Wudu District and Wenxian County along the Bailong River basins and cold-spot areas in Qin'an County and Gangu County.Conclusions: There was spatial clustering and hot spots of the reported VL incidence in Gansu Province from 1993 to 2023. Intensified surveillance and control is required to prevent the spread of VL.","PeriodicalId":38874,"journal":{"name":"中国血吸虫病防治杂志","volume":"36 4","pages":"334-338"},"PeriodicalIF":0.0,"publicationDate":"2024-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142355903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Progress of interruption of schistosomiasis transmission and prospects in Yunnan Province]. [云南省阻断血吸虫病传播的进展与前景]。

Q3 Medicine

中国血吸虫病防治杂志

Pub Date : 2024-07-26 DOI: 10.16250/j.32.1374.2024037

Y Zhang, L Wang, X Feng, M Wu, M Shen, H Jiang, J Song, J Sun, C Chen, J Yan, Z Zhang, J Zhou, Y Dong, C Du

Schistosomiasis was once hyper-endemic in Yunnan Province. Following concerted efforts for over 70 years, remarkable achievements have been made for schistosomiasis control in the province. In 2004, the Mid- and Long-term Plan for Schistosomiasis Prevention and Control in Yunnan Province was initiated in Yunnan Province, and the target for transmission control of schistosomiasis was achieved in the province in 2009. Following the subsequent implementation of the Outline for Key Projects in Integrated Schistosomiasis Control Program (2009-2015) and the 13th Five - year Plan for Schistosomiasis Control in Yunnan Province, no acute schistosomiasis had been identified in Yunnan Province for successive 12 years, and no local Schistosoma japonicum infections had been detected in humans, animals or Oncomelania hupensis snails for successive 6 years in the province by the end of 2020. The transmission of schistosomiasis was interrupted in Yunnan Province in 2020. This review summarizes the history of schistosomiasis, changes in schistosomiasis prevalence and progress of schistosomiasis control in Yunnan Province, and proposes the future priorities for schistosomiasis control in the province.

血吸虫病曾一度在云南省高流行。经过 70 多年的共同努力，云南省血吸虫病防治工作取得了显著成绩。2004 年，云南省启动了《云南省血吸虫病防治中长期规划》，2009 年全省实现了血吸虫病传播控制目标。随着《云南省血吸虫病综合防治规划重点项目实施纲要（2009-2015 年）》和《云南省血吸虫病防治 "十三五 "规划》的相继实施，到 2020 年底，云南省已连续 12 年未发现急性血吸虫病，连续 6 年未发现人、畜和钉螺感染本地血吸虫病。云南省血吸虫病传播于 2020 年中断。本综述总结了云南省血吸虫病的历史、血吸虫病流行的变化和血吸虫病防治的进展，并提出了今后云南省血吸虫病防治工作的重点。

{"title":"[Progress of interruption of schistosomiasis transmission and prospects in Yunnan Province].","authors":"Y Zhang, L Wang, X Feng, M Wu, M Shen, H Jiang, J Song, J Sun, C Chen, J Yan, Z Zhang, J Zhou, Y Dong, C Du","doi":"10.16250/j.32.1374.2024037","DOIUrl":"https://doi.org/10.16250/j.32.1374.2024037","url":null,"abstract":"Schistosomiasis was once hyper-endemic in Yunnan Province. Following concerted efforts for over 70 years, remarkable achievements have been made for schistosomiasis control in the province. In 2004, the Mid- and Long-term Plan for Schistosomiasis Prevention and Control in Yunnan Province was initiated in Yunnan Province, and the target for transmission control of schistosomiasis was achieved in the province in 2009. Following the subsequent implementation of the Outline for Key Projects in Integrated Schistosomiasis Control Program (2009-2015) and the 13th Five - year Plan for Schistosomiasis Control in Yunnan Province, no acute schistosomiasis had been identified in Yunnan Province for successive 12 years, and no local Schistosoma japonicum infections had been detected in humans, animals or Oncomelania hupensis snails for successive 6 years in the province by the end of 2020. The transmission of schistosomiasis was interrupted in Yunnan Province in 2020. This review summarizes the history of schistosomiasis, changes in schistosomiasis prevalence and progress of schistosomiasis control in Yunnan Province, and proposes the future priorities for schistosomiasis control in the province.","PeriodicalId":38874,"journal":{"name":"中国血吸虫病防治杂志","volume":"36 4","pages":"422-427"},"PeriodicalIF":0.0,"publicationDate":"2024-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142355901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Prevalence of Anaplasma infections in sheep and goats in Anhui Province in 2020]. [2020年安徽省绵羊、山羊无原体感染流行情况分析]。

Q3 Medicine

中国血吸虫病防治杂志

Pub Date : 2024-07-25 DOI: 10.16250/j.32.1374.2023232

X Wu, J Wang, S Gao, X Luo, Q Li, D Chen, X Liu, Y Gu, W Li

Objective: To investigate the prevalence and molecular characteristics of Anaplasma infections in sheep and goats in Anhui Province in 2020, so as to provide insights into ovine anaplasmosis prevention and control.

Methods: A total of 355 fresh blood samples were collected from 7 sheep and goat farms in Linquan County of Fuyang City, Lixin County of Bozhou City, Yu'an District of Lu'an City, Wangjiang County of Anqing City, Nanling County of Wuhu City, and Tianchang City and Fengyang County of Chuzhou City in Anhui Province from June to December 2020. A. bovis and A. phagocytophilum 16S ribosomal RNA (16S rRNA) gene, A. ovis major surface protein 4 (MSP4) gene and A. capra citric acid synthase (gltA) gene were amplified using PCR assay in all blood samples, and the prevalence of A. bovis, A. phagocytophilum, A. ovis and A. capra infections was calculated in sheep and goats. In addition, the positive amplification products were sequenced and subjected to genetic evolutionary analysis.

Results: The overall prevalence of Anaplasma infections was 17.5% (62/355) in sheep and goats in Anhui Province, and the prevalence of A. bovis, A. phagocytophilum, A. ovis and A. capra infections was 2.8% (10/355), 2.5% (9/355), 2.5% (9/355), and 7.0% (25/355), while the prevalence of A. bovis and A. phagocytophilum, A. phagocytophilum and A. ovis, A. phagocytophilum and A. capra and A. bovis, A. phagocytophilum and A. ovis co-infections was 0.8% (3/355), 1.1% (4/355), 0.3% (1/355) and 0.3% (1/355), respectively. No Anaplasma was detected in the sheep and goat farms in Fengyang County, while at least three Anaplasma species were detected in other sheep and goat farms, with co-infections of multiple Anaplasma species identified. The prevalence of Anaplasma infections was 14.7% (24/163) in goats and 19.8% (38/192) in sheep, and the prevalence of Anaplasma infections was 31.0% (31/100) in goats and sheep under 6 months of age, and 12.2% (31/255) in goats and sheep at ages of 6 months and older, respectively. A. bovis, A. phagocytophilum, A. ovis and A. capra were identified in sheep and goats of different breeds and ages.

Conclusions: Multiple Anaplasma species infections were commonly prevalent in goats and sheep in Anhui Province in 2020, notably A. phagocytophilum, A. ovis and A. capra, which have zoonotic risks. Improved surveillance and prevention and control of Anaplasma infections are required in sheep and goats in Anhui Province.

目的：了解2020年安徽省绵羊和山羊无形体感染的流行情况及分子特征，为绵羊无形体病的防治提供依据。方法：于2020年6 - 12月在安徽省阜阳市临泉县、亳州市立新县、六安市余安区、安庆市望江县、芜湖市南陵县、滁州市天长市和凤阳县7个绵羊和山羊养殖场采集新鲜血液样本355份。采用PCR法在所有血液样本中扩增牛弧菌、嗜吞噬细胞弧菌16S核糖体RNA （16S rRNA）基因、羊弧菌主要表面蛋白4 （MSP4）基因和羊角弧菌柠檬酸合成酶（gltA）基因，计算绵羊和山羊中牛弧菌、嗜吞噬细胞弧菌、山羊弧菌和嗜吞噬细胞弧菌的感染率。对阳性扩增产物进行测序和遗传进化分析。结果:红孢子虫属感染的总发病率为17.5%(62/355)在安徽省绵羊和山羊,和a .宝的患病率,a . phagocytophilum a羊属和a·卡普拉感染为2.8%(10/355),2.5%(9/355),2.5%(9/355)和7.0%(25/355),而a .宝的患病率和a . phagocytophilum phagocytophilum和a .羊属a phagocytophilum a和a·卡普拉和宝,a . phagocytophilum和a .羊属病毒是0.8%(3/355),1.1%(4/355),0.3%(1/355)和0.3% (1/355),分别。凤阳县绵羊和山羊养殖场未检出无原体，而其他绵羊和山羊养殖场检出至少3种无原体，并发现多种无原体共感染。山羊和绵羊无原体感染率分别为14.7%（24/163）和19.8%(38/192)，6月龄以下和6月龄及以上绵羊无原体感染率分别为31.0%（31/100）和12.2%（31/255）。在不同品种、不同年龄的绵羊和山羊中鉴定出牛、嗜吞噬细胞、山羊和卡普拉单胞杆菌。结论：2020年安徽省山羊和绵羊中普遍存在多种无原体感染，其中以嗜吞噬单胞菌、鹅单胞菌和卡普拉单胞菌感染最为突出，具有人畜共患风险。安徽省绵羊和山羊无原体感染监测和防控工作有待加强。

{"title":"[Prevalence of Anaplasma infections in sheep and goats in Anhui Province in 2020].","authors":"X Wu, J Wang, S Gao, X Luo, Q Li, D Chen, X Liu, Y Gu, W Li","doi":"10.16250/j.32.1374.2023232","DOIUrl":"https://doi.org/10.16250/j.32.1374.2023232","url":null,"abstract":"Objective: To investigate the prevalence and molecular characteristics of Anaplasma infections in sheep and goats in Anhui Province in 2020, so as to provide insights into ovine anaplasmosis prevention and control.Methods: A total of 355 fresh blood samples were collected from 7 sheep and goat farms in Linquan County of Fuyang City, Lixin County of Bozhou City, Yu'an District of Lu'an City, Wangjiang County of Anqing City, Nanling County of Wuhu City, and Tianchang City and Fengyang County of Chuzhou City in Anhui Province from June to December 2020. A. bovis and A. phagocytophilum 16S ribosomal RNA (16S rRNA) gene, A. ovis major surface protein 4 (MSP4) gene and A. capra citric acid synthase (gltA) gene were amplified using PCR assay in all blood samples, and the prevalence of A. bovis, A. phagocytophilum, A. ovis and A. capra infections was calculated in sheep and goats. In addition, the positive amplification products were sequenced and subjected to genetic evolutionary analysis.Results: The overall prevalence of Anaplasma infections was 17.5% (62/355) in sheep and goats in Anhui Province, and the prevalence of A. bovis, A. phagocytophilum, A. ovis and A. capra infections was 2.8% (10/355), 2.5% (9/355), 2.5% (9/355), and 7.0% (25/355), while the prevalence of A. bovis and A. phagocytophilum, A. phagocytophilum and A. ovis, A. phagocytophilum and A. capra and A. bovis, A. phagocytophilum and A. ovis co-infections was 0.8% (3/355), 1.1% (4/355), 0.3% (1/355) and 0.3% (1/355), respectively. No Anaplasma was detected in the sheep and goat farms in Fengyang County, while at least three Anaplasma species were detected in other sheep and goat farms, with co-infections of multiple Anaplasma species identified. The prevalence of Anaplasma infections was 14.7% (24/163) in goats and 19.8% (38/192) in sheep, and the prevalence of Anaplasma infections was 31.0% (31/100) in goats and sheep under 6 months of age, and 12.2% (31/255) in goats and sheep at ages of 6 months and older, respectively. A. bovis, A. phagocytophilum, A. ovis and A. capra were identified in sheep and goats of different breeds and ages.Conclusions: Multiple Anaplasma species infections were commonly prevalent in goats and sheep in Anhui Province in 2020, notably A. phagocytophilum, A. ovis and A. capra, which have zoonotic risks. Improved surveillance and prevention and control of Anaplasma infections are required in sheep and goats in Anhui Province.","PeriodicalId":38874,"journal":{"name":"中国血吸虫病防治杂志","volume":"36 6","pages":"620-625"},"PeriodicalIF":0.0,"publicationDate":"2024-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143013507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0