Pub Date : 1994-06-30DOI: 10.14921/JSCC1971B.23.2_150
G. Meng, F. Mashige, K. Kitamura, Shinsaku Ohnishi, A. Ohkubo
{"title":"Measurement of Sulfated Bile Acids in Urine and its Usefulness as a Liver Function Test","authors":"G. Meng, F. Mashige, K. Kitamura, Shinsaku Ohnishi, A. Ohkubo","doi":"10.14921/JSCC1971B.23.2_150","DOIUrl":"https://doi.org/10.14921/JSCC1971B.23.2_150","url":null,"abstract":"","PeriodicalId":39360,"journal":{"name":"Japanese Journal of Clinical Chemistry","volume":"23 1","pages":"150-157"},"PeriodicalIF":0.0,"publicationDate":"1994-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66735113","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1994-06-30DOI: 10.14921/JSCC1971B.23.2_158
Yuji Suzuki, Y. Sakagishi
Summaru We studied the diazo reaction of the water-soluble photoproducts of bilirubin using nine kinds of diazonium salts to select the diazonium salt most suitable for the determination of serum bilirubin. The diazonium salt of 3-nitroaniline was found to be more suitable than that of sulfanilic acid used extensively in clinical practice. This diazonium salt reacted readily with not only bilirubin but also the photoproducts, and the reaction of patients' serum bilirubin was completed in 2 or 3 min. The change in the measurement values obtained using this diazonium salt before and after irradiation with a fluorescent lamp was smaller than that obtained by the enzymatic method or the diazo method using the diazotized sulfanilic acid.
{"title":"Determination of serum bilirubin by the diazo method using the diazotized 3-nitroaniline reacting readily with the photoproducts of bilirubin","authors":"Yuji Suzuki, Y. Sakagishi","doi":"10.14921/JSCC1971B.23.2_158","DOIUrl":"https://doi.org/10.14921/JSCC1971B.23.2_158","url":null,"abstract":"Summaru We studied the diazo reaction of the water-soluble photoproducts of bilirubin using nine kinds of diazonium salts to select the diazonium salt most suitable for the determination of serum bilirubin. The diazonium salt of 3-nitroaniline was found to be more suitable than that of sulfanilic acid used extensively in clinical practice. This diazonium salt reacted readily with not only bilirubin but also the photoproducts, and the reaction of patients' serum bilirubin was completed in 2 or 3 min. The change in the measurement values obtained using this diazonium salt before and after irradiation with a fluorescent lamp was smaller than that obtained by the enzymatic method or the diazo method using the diazotized sulfanilic acid.","PeriodicalId":39360,"journal":{"name":"Japanese Journal of Clinical Chemistry","volume":"23 1","pages":"158-163"},"PeriodicalIF":0.0,"publicationDate":"1994-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.14921/JSCC1971B.23.2_158","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66735154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1994-06-30DOI: 10.14921/JSCC1971B.23.2_145
H. Ichiki, N. Kohno, S. Fujioka, H. Hamada, Kouki Watanabe, K. Hiwada
{"title":"Evaluation of Serum Copper/Zinc Ratio as a Tumor Marker for Lung Cancer","authors":"H. Ichiki, N. Kohno, S. Fujioka, H. Hamada, Kouki Watanabe, K. Hiwada","doi":"10.14921/JSCC1971B.23.2_145","DOIUrl":"https://doi.org/10.14921/JSCC1971B.23.2_145","url":null,"abstract":"","PeriodicalId":39360,"journal":{"name":"Japanese Journal of Clinical Chemistry","volume":"23 1","pages":"145-149"},"PeriodicalIF":0.0,"publicationDate":"1994-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66735063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1994-03-31DOI: 10.14921/JSCC1971B.23.1_1
K. Arisue
{"title":"Development of a Method for Measuring Serum Anti-Thyroglobulin Antibody Using Chemiluminescence","authors":"K. Arisue","doi":"10.14921/JSCC1971B.23.1_1","DOIUrl":"https://doi.org/10.14921/JSCC1971B.23.1_1","url":null,"abstract":"","PeriodicalId":39360,"journal":{"name":"Japanese Journal of Clinical Chemistry","volume":"23 1","pages":"1-7"},"PeriodicalIF":0.0,"publicationDate":"1994-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66734987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1994-03-31DOI: 10.14921/JSCC1971B.23.1_21
Yuji Suzuki, Y. Sakagishi
{"title":"Studies on the Diazo Reaction of Three Bilirubin Isomers","authors":"Yuji Suzuki, Y. Sakagishi","doi":"10.14921/JSCC1971B.23.1_21","DOIUrl":"https://doi.org/10.14921/JSCC1971B.23.1_21","url":null,"abstract":"","PeriodicalId":39360,"journal":{"name":"Japanese Journal of Clinical Chemistry","volume":"23 1","pages":"21-25"},"PeriodicalIF":0.0,"publicationDate":"1994-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66735005","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1994-01-01DOI: 10.14921/JSCC1971B.23.1_15
Kojiro Matsumoto, M. Ishibashi, N. Takiyama, H. Yuki
{"title":"Carnitine Deficiencies Associated with Valproic Acid and Other Anticonvulsant Therapy","authors":"Kojiro Matsumoto, M. Ishibashi, N. Takiyama, H. Yuki","doi":"10.14921/JSCC1971B.23.1_15","DOIUrl":"https://doi.org/10.14921/JSCC1971B.23.1_15","url":null,"abstract":"","PeriodicalId":39360,"journal":{"name":"Japanese Journal of Clinical Chemistry","volume":"23 1","pages":"15-20"},"PeriodicalIF":0.0,"publicationDate":"1994-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66734994","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1994-01-01DOI: 10.14921/JSCC1971B.23.1_8
K. Arisue
{"title":"Development of Highly Sensitive Chemiluminescent EIA for Thyroglobulin","authors":"K. Arisue","doi":"10.14921/JSCC1971B.23.1_8","DOIUrl":"https://doi.org/10.14921/JSCC1971B.23.1_8","url":null,"abstract":"","PeriodicalId":39360,"journal":{"name":"Japanese Journal of Clinical Chemistry","volume":"23 1","pages":"8-14"},"PeriodicalIF":0.0,"publicationDate":"1994-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66735048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1993-12-31DOI: 10.14921/JSCC1971B.22.4_230
K. Ito, M. Maeda, A. Tsuji
{"title":"Enzyme Immunoassay of Cholecystokinin in Human Plasma Using Immuno-Affinity Column Extraction as Pretreatment","authors":"K. Ito, M. Maeda, A. Tsuji","doi":"10.14921/JSCC1971B.22.4_230","DOIUrl":"https://doi.org/10.14921/JSCC1971B.22.4_230","url":null,"abstract":"","PeriodicalId":39360,"journal":{"name":"Japanese Journal of Clinical Chemistry","volume":"94 1","pages":"230-237"},"PeriodicalIF":0.0,"publicationDate":"1993-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66734980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1993-09-30DOI: 10.14921/JSCC1971B.22.3_162
M. Kinoshita, Sadahito Shin, S. Hamada, T. Aono
{"title":"Human Papillomavirus Integration into the Host Cell Genome during the Developmental Stage of Cervical Cancer","authors":"M. Kinoshita, Sadahito Shin, S. Hamada, T. Aono","doi":"10.14921/JSCC1971B.22.3_162","DOIUrl":"https://doi.org/10.14921/JSCC1971B.22.3_162","url":null,"abstract":"","PeriodicalId":39360,"journal":{"name":"Japanese Journal of Clinical Chemistry","volume":"22 1","pages":"162-167"},"PeriodicalIF":0.0,"publicationDate":"1993-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66734927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1993-09-30DOI: 10.14921/JSCC1971B.22.3_156
R. Uzawa, K. Su, Taiichiro Kobayashi, Hiroyuki Watanabe, K. Fukuchi, Y. Takagi, K. Gomi, Chang Gu Kang
Atrial natriuretic peptide (ANP) (10-8mol/l), brain natriuretic peptide (BNP) (10-8mol/l), the protein kinase C (PKC) inhibitors H-7 (10-5mol/l) and staurosporin (10-8mol/l) suppressed aldosterone secretion in cultured bovine adrenal glomerulosa cells by 40 to 50 % compared with untreated control cells. When cells incubated with 10-8mol/l angiotensin II (All) were also treated with ANP, BNP, or PKC inhibitors, aldosterone secretion was 50 to 60 % of that seen in untreated cells. ANP, BNP and PKC inhibitors suppressing the expression of PKC, suggested that PKC plays a role in aldosterone secretion. Our results suggest that ANP and BNP may have an unknown second messenger pathway in which the suppression of PKC is essential for the ex-
{"title":"Mechanism of ANP and BNP Action on the Suppression of Aldosterone Secretion by Cultured Bovine Adrenal Glomerulosa Cells","authors":"R. Uzawa, K. Su, Taiichiro Kobayashi, Hiroyuki Watanabe, K. Fukuchi, Y. Takagi, K. Gomi, Chang Gu Kang","doi":"10.14921/JSCC1971B.22.3_156","DOIUrl":"https://doi.org/10.14921/JSCC1971B.22.3_156","url":null,"abstract":"Atrial natriuretic peptide (ANP) (10-8mol/l), brain natriuretic peptide (BNP) (10-8mol/l), the protein kinase C (PKC) inhibitors H-7 (10-5mol/l) and staurosporin (10-8mol/l) suppressed aldosterone secretion in cultured bovine adrenal glomerulosa cells by 40 to 50 % compared with untreated control cells. When cells incubated with 10-8mol/l angiotensin II (All) were also treated with ANP, BNP, or PKC inhibitors, aldosterone secretion was 50 to 60 % of that seen in untreated cells. ANP, BNP and PKC inhibitors suppressing the expression of PKC, suggested that PKC plays a role in aldosterone secretion. Our results suggest that ANP and BNP may have an unknown second messenger pathway in which the suppression of PKC is essential for the ex-","PeriodicalId":39360,"journal":{"name":"Japanese Journal of Clinical Chemistry","volume":"22 1","pages":"156-161"},"PeriodicalIF":0.0,"publicationDate":"1993-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66734917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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