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Telehealth in long-term neurological conditions: the potential, the challenges and the key recommendations. 长期神经疾病的远程保健:潜力、挑战和主要建议。
Q3 Engineering Pub Date : 2022-08-01 Epub Date: 2022-02-25 DOI: 10.1080/03091902.2022.2040625
Liam Knox, Christopher McDermott, Esther Hobson

Long-term neurological conditions (LTNCs) cause physical and psychological symptoms that have a significant impact on activities of daily living and quality of life. Multidisciplinary teams are effective at providing treatment for people with LTNCs; however, access to such services by people with disabilities can be difficult and as a result, good quality care is not universal. One potential solution is telehealth. This review describes the potential of telehealth to support people with LTNCs, the challenges of designing and implementing these systems, and the key recommendations for those involved in telehealth to facilitate connected services that can benefit patients, carers and healthcare professionals. These recommendations include understanding the problems posed by LTNCs and the needs of the end-user through a person-centred approach. We discuss how to work collaboratively and use shared learning, and consider how to effectively evaluate the intervention at every stage of the development process.

长期神经系统疾病(ltnc)引起的生理和心理症状对日常生活活动和生活质量有重大影响。多学科团队在为ltnc患者提供治疗方面是有效的;然而,残疾人获得这些服务可能很困难,因此,高质量的护理并不普遍。一个潜在的解决方案是远程医疗。这篇综述描述了远程医疗支持长期nc患者的潜力,设计和实施这些系统的挑战,以及为参与远程医疗的人员提供的关键建议,以促进可使患者、护理人员和卫生保健专业人员受益的互联服务。这些建议包括通过以人为本的方法了解长期非传染性疾病所带来的问题和最终用户的需求。我们讨论如何协同工作和使用共享学习,并考虑如何在发展过程的每个阶段有效地评估干预。
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引用次数: 3
Developing a paediatric healthcare research network: key learnings from the 'starworks' child prosthetics project. 发展儿科医疗保健研究网络:从“starworks”儿童假肢项目中获得的重要经验。
Q3 Engineering Pub Date : 2022-08-01 Epub Date: 2022-06-28 DOI: 10.1080/03091902.2022.2089251
Abigail Needham, Gemma Wheeler, Nathaniel Mills, John Head

The context of child prosthetics is a complex and important area for research and innovation. Yet, like many areas of paediatric medical technology development, there are several barriers to innovating specifically for the unique needs of children (i.e., a relatively small patient population or 'market'). As such, much child prosthetics technology is developed from the downsizing of adult prosthetics, leading to suboptimal outcomes for children and young people. Since 2016, the Starworks Child Prosthetics Research Network has been exploring this space, bringing children and their families together with key opinion leaders from the NHS, clinical Academia and leading National Research Centres with capabilities in child prosthetics with the aim of increasing research across the system. Above all else, Starworks is centred on the needs of children and their families, ensuring they have an equal voice in driving the ongoing research agenda. This article will share key learnings from the creation and development of the Starworks Network that may be applicable and/or adaptable across a wider paediatric medical technology research and innovation landscape. In particular it will discuss how it addressed three key aims of; (1) Addressing child-specific issues; (2) Building a sustainable network; and (3) Fostering impactful innovation.

儿童假肢是一个复杂而重要的研究和创新领域。然而,与儿科医疗技术发展的许多领域一样,针对儿童的独特需求(即相对较小的患者群体或“市场”)进行创新存在一些障碍。因此,许多儿童假肢技术是从成人假肢的缩小发展而来的,导致儿童和年轻人的结果不理想。自2016年以来,Starworks儿童假肢研究网络一直在探索这一领域,将儿童及其家人与来自NHS、临床学术界和具有儿童假肢能力的领先国家研究中心的主要意见领袖聚集在一起,目的是增加整个系统的研究。最重要的是,Starworks以儿童及其家庭的需求为中心,确保他们在推动正在进行的研究议程方面拥有平等的发言权。本文将分享从Starworks网络的创建和发展中获得的关键经验,这些经验可能适用于和/或适应于更广泛的儿科医疗技术研究和创新领域。它将特别讨论如何实现以下三个关键目标:处理儿童特有问题;(2)构建可持续发展的网络;(3)促进有影响力的创新。
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引用次数: 2
Keeping patient and public partnership at the heart of medical technology development during Covid-19: examples of adaptive practice. 在2019冠状病毒病期间,将患者和公众伙伴关系作为医疗技术发展的核心:适应性实践的例子。
Q3 Engineering Pub Date : 2022-08-01 Epub Date: 2022-07-27 DOI: 10.1080/03091902.2022.2089258
Lise Sproson, Nathaniel Mills, Liz Pryde, Ade Adebajo, David Coyle, Jennifer Preston, Daniel Blackburn, Heidi Christensen, Vitaveska Lanfranchi

NIHR (National Institute for Health Research) Devices for Dignity MedTech Cooperative (D4D) and NIHR Children and Young People MedTech Cooperative (CYPMedTech) have established track records in keeping patient and public involvement (PPI) at the core of medical technology development, evaluation and implementation. The 2020 global COVID-19 pandemic presented significant challenges to maintaining this crucial focus. In this paper we describe prior successful methodologies and share examples of the adaptations made in order to continue to engage with patients and the public throughout the pandemic and beyond. We reflect on learning gained from these experiences, and new areas of scope and focus relating to broadening the reach of engagement and representation, along with associated resource requirements and impact metrics.

NIHR(美国国家卫生研究所)尊严医疗技术合作装置(D4D)和NIHR儿童和青少年医疗技术合作装置(CYPMedTech)在将患者和公众参与(PPI)作为医疗技术开发、评估和实施的核心方面建立了良好的记录。2020年全球COVID-19大流行对保持这一关键重点提出了重大挑战。在本文中,我们描述了以前成功的方法,并分享了为在大流行期间和以后继续与患者和公众接触而进行的调整的例子。我们反思从这些经验中获得的经验,以及与扩大参与和代表性范围有关的新范围和重点领域,以及相关的资源需求和影响指标。
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引用次数: 2
User attitudes towards virtual home assessment technologies. 用户对虚拟家庭评估技术的态度。
Q3 Engineering Pub Date : 2022-08-01 Epub Date: 2022-06-22 DOI: 10.1080/03091902.2022.2089250
V Lanfranchi, N Jones, J Read, C Fegan, B Field, E Simpson, C Revitt, P Cudd, F Ciravegna
Abstract Telehealth has long been highlighted as a way to solve issues of efficiency and effectiveness in healthcare and to improve patients’ care and has become fundamental to address patients’ needs during the COVID-19 pandemic; however previous studies have shown mixed results in the user acceptance of such technologies. Whilst many previous studies have focussed on clinical application of telehealth, we focus on the adoption of telehealth for virtual assessments visits aimed to evaluate the suitability of a property where a patient is discharged, and eventual adaptations needed. We present a study of stakeholders’ attitudes towards such virtual assessment visits. The study has been carried out with healthcare professionals and patients and allowed us to identify user attitudes, barriers and facilitators for the success of virtual assessment visits from the point of view of healthcare professionals and patients. Finally, we discuss implications for designers of telehealth services and guidelines that can be derived from our study.
长期以来,远程医疗一直被强调为解决医疗保健效率和有效性问题以及改善患者护理的一种方式,并已成为解决COVID-19大流行期间患者需求的基础;然而,先前的研究表明,用户对这些技术的接受程度好坏参半。虽然以前的许多研究都集中在远程医疗的临床应用上,但我们的重点是采用远程医疗进行虚拟评估访问,旨在评估患者出院的财产的适用性,以及最终需要的适应性。我们提出了利益相关者对这种虚拟评估访问的态度的研究。这项研究是在医疗保健专业人员和患者中进行的,使我们能够从医疗保健专业人员和患者的角度确定虚拟评估访问成功的用户态度、障碍和促进因素。最后,我们讨论了可以从我们的研究中得出的远程医疗服务和指导方针的设计者的启示。
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引用次数: 2
Co-design of digital learning resources for care workers: reflections on the neurocare knowhow project. 护理人员数字化学习资源的协同设计:对神经护理知识项目的思考。
Q3 Engineering Pub Date : 2022-08-01 Epub Date: 2022-07-19 DOI: 10.1080/03091902.2022.2089253
Cathy Soreny, Philippa Takhar, Emma Vickers, Rebecca Bartlett, Elizabeth Coates, Theocharis Stavroulakis, Emily Fox, Heather Davidson, Adam Harrison, Christopher McDermott

Neurocare Knowhow is an online learning platform for care workers who support people with neurological conditions. Care workers often do not receive specialist training around neurological conditions and can experience anxiety and apprehension about caring for this group. Neurocare Knowhow aims to increase care workers' knowledge and confidence. Featuring flexible and personalisable digital features, in combination with documentary video and audio, it offers an alternative to traditional e-learning, moving away from longform didactic courses to flexible on-the-go learning. This co-design project worked closely with people with neurological conditions, their families, care workers and care organisation managers to validate the need and develop a proof of concept pilot. Co-design activity took place across multiple workshops in person and online. These gathered detailed insights into preferred features that support engaging online learning. The platform offers learning across diverse neurological conditions as a whole, with a focus on shared symptoms and challenges encountered by people with neurological conditions. Ongoing development to scale the pilot up to meet an anticipated national audience includes a focus on artificial intelligence to support searches at a moment of need and a range of personalisable features for individual and team learning.

Neurocare know是一个在线学习平台,面向为神经系统疾病患者提供支持的护理工作者。护理人员通常没有接受过有关神经系统疾病的专业培训,在照顾这一群体时可能会感到焦虑和忧虑。神经护理知识旨在增加护理人员的知识和信心。它具有灵活和个性化的数字功能,结合纪录片视频和音频,为传统的电子学习提供了另一种选择,从冗长的教学课程转向灵活的即时学习。这个共同设计项目与神经系统疾病患者、他们的家人、护理人员和护理组织经理密切合作,以验证需求并开发概念验证试点。共同设计活动在多个面对面和在线研讨会上进行。这些研究收集了支持参与在线学习的首选功能的详细见解。该平台提供各种神经系统疾病的整体学习,重点是神经系统疾病患者遇到的共同症状和挑战。正在进行的扩大试点规模以满足预期的全国受众的开发包括关注人工智能,以支持在需要时进行搜索,以及为个人和团队学习提供一系列个性化功能。
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引用次数: 2
Effect of washing on quality, breathability performance and reusability of disposable face masks. 洗涤对一次性口罩质量、透气性和可重复使用性的影响。
Q3 Engineering Pub Date : 2022-07-01 Epub Date: 2022-03-21 DOI: 10.1080/03091902.2022.2043476
S Hassani, L Henni, A Sidali, A Naitbouda, A Khereddine, D Dergham, F Lekoui

Disposable face masks are among the personal protective equipment (PPE) that highly contribute to protecting people in the context of the current COVID-19 pandemic. Health authorities recommend wearing a mask as a barrier measure to limit the spread of viral respiratory diseases. During the first waves of the pandemic, besides professional high-quality PPE, decontaminated disposable mask reuse and homemade cloth masks were allowed due to scarcities. This work introduces a simple method based on-time history of the differential pressure, and an easy to use the setup for the testing of different kinds of respiratory protective masks for the purposes of quality control and evaluation of air permeability performance. The standard mask testing method and the new proposed approach were then used to evaluate the effect of machine washing on the widely used type of disposable masks; namely the surgical (medical) face masks. The objective is to determine the number of acceptable washing cycles that this kind of mask can withstand before losing its performance in terms of breathability and airflow resistance. Other quality characteristics such as material (fibres) degradation and hydrophobicity are investigated. Degradation mechanisms due to washing cycles for the different mask constituent layers were studied by scanning electron microscopy (SEM) imaging. This work is an attempt to contribute to the determination of the reusability threshold of general-purpose disposable surgical type face masks thereby contributing to the reduction of environmental concerns. Results in terms of the studied above parameters suggest limiting the reuse of standard type surgical masks to only one machine washing cycle.

在当前COVID-19大流行的背景下,一次性口罩是非常有助于保护人们的个人防护装备之一。卫生当局建议戴口罩作为一种屏障措施,以限制病毒性呼吸道疾病的传播。在大流行的第一波期间,由于缺乏,除了专业的高质量个人防护装备外,还允许重复使用经过消毒的一次性口罩和自制布口罩。本文介绍了一种基于实时压差历史的简单方法,以及一种易于使用的装置,用于测试不同种类的呼吸防护口罩的质量控制和透气性能评估。然后采用标准口罩检测方法和新方法评估了机洗对广泛使用的一次性口罩的影响;即外科(医疗)口罩。目的是确定这种口罩在失去其透气性和气流阻力方面的性能之前可以承受的可接受的洗涤循环次数。其他质量特性,如材料(纤维)的降解和疏水性进行了研究。通过扫描电子显微镜(SEM)成像研究了不同膜层在不同洗涤周期下的降解机理。这项工作是一项尝试,有助于确定通用一次性外科口罩的可重复使用阈值,从而有助于减少对环境的关注。根据上述参数的研究结果,建议将标准型医用口罩的重复使用限制在一次机洗周期内。
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引用次数: 2
Design considerations for piezocomposite materials for electrical stimulation in medical implants. 医用植入物电刺激用压电复合材料的设计考虑。
Q3 Engineering Pub Date : 2022-07-01 DOI: 10.1080/03091902.2022.2080881
Ember Krech, Evan Haas, Grace Tideman, Bonnie Reinsch, Elizabeth Friis

Incidence of non-union following long bone fracture fixation and spinal fusion procedures is increasing, and very costly for patients and the medical system. Direct current (DC) electrical stimulation has shown success as an adjunct therapy to stimulate bone healing and increase surgery success rates, though drawbacks of current devices and implantable battery packs have limited widespread use. Energy harvesting utilising piezoelectric materials has been widely studied for powering devices without a battery, and a preclinical animal study has shown efficacy of a piezocomposite spinal fusion implant resulting in faster, more robust fusion. Most piezoelectric energy harvesters operate most effectively at high frequencies, limiting power generation from loads experienced by orthopaedic implants during human motion. This work characterises the efficient power generation capability of a novel composite piezoelectric material under simulated walking loads. Building on compliant layer adaptive composite stacks (CLACS), the power generation of mixed-mode CLACS (MMCLACS) is defined. Utilising poling direction to capitalise on in-plane strain generation due to compliant layer expansion, MMCLACS significantly increased power output compared to a standard piezo stack. The combination of radial and through-thickness poled piezoelectric elements within a stack to create MMCLACS significantly increases power generation under low-frequency dynamic loads. This technology can be adapted to a variety of architectures and assembled as a load-bearing energy harvester within current implants. MMCLACS integrated with implants would provide enough power to deliver bone healing electrical stimulation directly to the fusion site, decreasing non-union rates, and also could provide quantitative assessment of healing progression through load sensing.

长骨骨折固定和脊柱融合术后不愈合的发生率正在增加,并且对患者和医疗系统来说非常昂贵。直流电刺激(DC)作为一种辅助疗法已经显示出成功,可以刺激骨愈合和提高手术成功率,尽管目前设备和可植入电池组的缺点限制了广泛使用。利用压电材料的能量收集已经被广泛研究,用于为没有电池的设备供电,一项临床前动物研究表明,压电复合材料脊柱融合植入物的效果更快,更坚固。大多数压电能量收集器在高频率下工作最有效,限制了矫形植入物在人体运动时所经历的负载产生的能量。这项工作表征了一种新型复合压电材料在模拟行走载荷下的高效发电能力。在柔性层自适应复合堆栈(CLACS)的基础上,定义了混合模式CLACS (MMCLACS)的发电方法。MMCLACS利用极化方向来利用由于柔性层扩展而产生的平面内应变,与标准压电堆叠相比,显着提高了功率输出。将径向和透厚极化压电元件组合在一起形成MMCLACS,可以显著提高低频动载荷下的发电量。该技术可以适应各种架构,并在当前植入物中组装为承载能量收集器。与植入物集成的MMCLACS将提供足够的功率,直接向融合部位提供骨愈合电刺激,降低骨不愈合率,还可以通过负载传感对愈合进展进行定量评估。
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引用次数: 1
Experimental investigation on effect of accelerated speed and rotor material on life of implantable micro-infusion pump tubing 加速转速和转子材料对植入式微输液泵管材寿命影响的实验研究
Q3 Engineering Pub Date : 2022-06-17 DOI: 10.1080/03091902.2022.2082575
S. Nair, A. D., Sudheesh K S
Abstract Peristaltic pumps have been put to use in various biomedical applications like devices for the transfer of body fluids as well as devices for controlled release of medication, including implantable infusion pumps. Out of the various components of a peristaltic pump, tubing is considered the most vulnerable part. This study focuses on the performance of Silicone micro-pump tubing used in such an implantable drug delivery device. Long-term implantable medical devices are expected to be operational for about 10 years. But experimental testing of the reliability of components under normal working speeds are time-consuming and thus delays the product development cycle. While simulating the conditions in the laboratory under accelerated speeds, the effect of increasing the speed must be accounted. In this study, the effect of accelerated speed and rotor material on pump tubing life is investigated. A test jig is developed which simulates the running conditions of the infusion pump for long-duration operation. Different rotor speeds and material configurations are investigated to obtain their effect on long-duration performance. Thermal effects on the roller junctions are studied and found that the Delrin silicone combination has twice the rise in junction temperature than the titanium silicone combination. The failure modes are inspected using microstructure analysis and the best configuration is identified.
蠕动泵已被用于各种生物医学应用,如体液转移装置以及药物控释装置,包括植入式输液泵。在蠕动泵的各种部件中,油管被认为是最脆弱的部分。本研究的重点是硅胶微泵管在这种植入式给药装置中的性能。长期植入式医疗设备预计将在10年内投入使用。但是,在正常工作速度下对部件进行可靠性的实验测试非常耗时,从而延迟了产品的开发周期。在实验室中模拟加速条件时,必须考虑提高速度的影响。研究了加速转速和转子材料对泵管寿命的影响。研制了一种模拟输液泵长时间运行工况的试验夹具。研究了不同的转子转速和材料配置对长时间性能的影响。研究了热效应对滚子结的影响,发现Delrin有机硅组合的结温升高幅度是钛有机硅组合的两倍。采用显微组织分析方法对失效模式进行了检测,确定了最佳的失效形态。
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引用次数: 0
Machine learning applied to healthcare: a conceptual review 机器学习在医疗保健中的应用:概念回顾
Q3 Engineering Pub Date : 2022-06-09 DOI: 10.1080/03091902.2022.2080885
M. Gomes, J. Kovaleski, R. Pagani, Vander Luiz da Silva
Abstract The technological inference in procedures applied to healthcare is frequently investigated in order to understand the real contribution to decision-making and clinical improvement. In this context, the theoretical field of machine learning has suitably presented itself. The objective of this research is to identify the main machine learning algorithms used in healthcare through the methodology of a systematic literature review. Considering the time frame of the last twenty years, 173 studies were mined based on established criteria, which allowed the grouping of algorithms into typologies. Supervised Learning, Unsupervised Learning, and Deep Learning were the groups derived from the studies mined, establishing 59 works employed. We expect that this research will stimulate investigations towards machine learning applications in healthcare.
摘要为了了解决策和临床改进的真正贡献,经常调查应用于医疗保健程序的技术推断。在这种背景下,机器学习的理论领域恰如其分地出现了。本研究的目的是通过系统文献综述的方法确定医疗保健中使用的主要机器学习算法。考虑到过去20年的时间框架,基于既定标准挖掘了173项研究,这些标准允许将算法分组到类型学中。有监督学习、无监督学习和深度学习是从所挖掘的研究中衍生出来的小组,建立了59个工作。我们期望这项研究将刺激对医疗保健中机器学习应用的调查。
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引用次数: 2
Investigating the effects of external pressure on coronary arteries with plaques and its role in coronary artery disease 研究外压对冠状动脉斑块的影响及其在冠状动脉疾病中的作用
Q3 Engineering Pub Date : 2022-06-08 DOI: 10.1080/03091902.2022.2081736
Jagath Gunasekera, Goksu Avdan, H. F. Lee, Soon-Bok Kweon, J. Klingensmith
Abstract The risk of an acute coronary event stems from the amount and type of plaque present, as well as the fluid and structural dynamics in the coronary artery. If the plaque’s structural stress exceeds the mechanical strength, the fibrous cap may rupture and lead to thrombosis. The patient is then likely to face a sudden myocardial infarction. An association between Coronary Heart Disease (CHD) and Sudden Cardiac Death (SCD) has been long recognised. For the first time, we are reporting a correlation between applied external pressure, such as Cardiopulmonary Resuscitation (CPR), coughing, sneezing, blowing one’s nose, etc., and diseased coronary artery plaque via 3 D coronary artery models and two-way Fluid-Solid Interaction (FSI) models. Shear and von Mises stresses inside arteries and plaques have been shown to play a major role in plaque development, progression of disease, and the likelihood of plaque rupture. Our results show a drastic change in maximum shear (300%) and von Mises stresses (500%) with increasing external pressure. This change may indicate an onset of imminent plaque rupture. Furthermore, FSI modelling indicates a strong correlation between plaque thickness, location, and external pressure. With further clinical and simulation studies, this information could be helpful in understanding potential limit pressure in the CPR process for patients with CHD.
摘要急性冠状动脉事件的风险源于斑块的数量和类型,以及冠状动脉中的流体和结构动力学。如果斑块的结构应力超过机械强度,纤维帽可能破裂并导致血栓形成。患者很可能会面临突发性心肌梗死。冠心病(CHD)和心源性猝死(SCD)之间的联系早已被人们所认识。我们首次报告了施加的外部压力,如心肺复苏(CPR)、咳嗽、打喷嚏、流鼻涕等,与病变的冠状动脉斑块之间的相关性 D冠状动脉模型和双向流体-固体相互作用(FSI)模型。动脉和斑块内的剪切应力和von Mises应力已被证明在斑块的发展、疾病进展和斑块破裂的可能性中起着重要作用。我们的结果表明,随着外压的增加,最大剪切应力(300%)和冯-米塞斯应力(500%)发生了剧烈变化。这种变化可能表明斑块即将破裂。此外,FSI模型显示斑块厚度、位置和外部压力之间有很强的相关性。随着进一步的临床和模拟研究,这些信息可能有助于了解冠心病患者心肺复苏过程中的潜在极限压力。
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引用次数: 1
期刊
Journal of Medical Engineering and Technology
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