Pub Date : 2019-01-17DOI: 10.35119/asjoo.v16i3.510
Li Long, Safinaz Mohd Khialdin, Nazila Binti Ahmad Azli
Aim: To analyse the epidemiological data, surgical technique, success rate, and complications of patients who underwent external DCR in Hospital Selayang from January 2015 to December 2016. Method: Retrospective case series. Results: A total of 21 eyes of 20 patients who underwent external DCR from January 2015 to December 2016 were identified and reviewed. There were 15 females (75%) and 5 males (25%). Age ranged from 5 to 75 years old, with a median age of 56 years old (IQR 23). Twelve patients presented with epiphora while eight patients presented with symptoms of dacryocystitis. One case was congenital, two were secondary nasolacrimal duct obstruction and the rest were primary nasolacrimal duct obstruction. All patients underwent external DCR under general anaesthesia. Silicone tube were inserted in 21 eyes, of which all were removed 3 months after the surgery except one patient whom had his tube dislodged accidentally. The overall success rate was 90.5% (n = 19), which was defined as no or minimal intermittent epiphora or no reflux on lacrimal irrigation at 12 months postoperative. There was one patient who had a cerebrospinal fluid leak treated successfully with intravenous antibiotics. Conclusion: The surgical success rate for external dacryocystorhinostomy was comparable to that of the global success rate of external DCR. This is attributed to the application of surgical technique such as anterior suspended flap modification and posterior flap excision.
{"title":"External dacryocystorhinostomy","authors":"Li Long, Safinaz Mohd Khialdin, Nazila Binti Ahmad Azli","doi":"10.35119/asjoo.v16i3.510","DOIUrl":"https://doi.org/10.35119/asjoo.v16i3.510","url":null,"abstract":"Aim: To analyse the epidemiological data, surgical technique, success rate, and complications of patients who underwent external DCR in Hospital Selayang from January 2015 to December 2016. \u0000Method: Retrospective case series. \u0000Results: A total of 21 eyes of 20 patients who underwent external DCR from January 2015 to December 2016 were identified and reviewed. There were 15 females (75%) and 5 males (25%). Age ranged from 5 to 75 years old, with a median age of 56 years old (IQR 23). Twelve patients presented with epiphora while eight patients presented with symptoms of dacryocystitis. One case was congenital, two were secondary nasolacrimal duct obstruction and the rest were primary nasolacrimal duct obstruction. All patients underwent external DCR under general anaesthesia. Silicone tube were inserted in 21 eyes, of which all were removed 3 months after the surgery except one patient whom had his tube dislodged accidentally. The overall success rate was 90.5% (n = 19), which was defined as no or minimal intermittent epiphora or no reflux on lacrimal irrigation at 12 months postoperative. There was one patient who had a cerebrospinal fluid leak treated successfully with intravenous antibiotics. \u0000Conclusion: The surgical success rate for external dacryocystorhinostomy was comparable to that of the global success rate of external DCR. This is attributed to the application of surgical technique such as anterior suspended flap modification and posterior flap excision.","PeriodicalId":39864,"journal":{"name":"Asian Journal of Ophthalmology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47881406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-01-17DOI: 10.35119/asjoo.v16i3.494
Rini Kusumawar Dhany
Aim: To evaluate the efficacy and complication of sutureless and glue-free conjunctival autograft for the management of primary pterygium over a period of one year. Methods: Prospective, interventional, hospital-based study. Twenty-four eyes of 24 patients with primary nasal pterygium were graded, and excision was performed by a single surgeon. To prevent recurrence, a free conjunctival autograft was taken from the superior quadrant from the same eye and the bare sclera was covered without the use of sutures or fibrin glue, allowing natural autologous coagulum of the recipient bed to act as a bioadhesive. The eye was patched for 24 hours. Postoperatively, patients were put on topical eye drops (polymixin 0.5%, neomycin 0.5%, and dexamethasone 1%) four times daily for four weeks, and oral antibiotics and methyl prednisolone 3x4 mg per day for 5 days. Patients were followed up postoperatively on day 1, 1 week, 6 weeks, 6 months, and 12 months. They were examined for haemorrhage, wound gape, graft shrinkage, granuloma, graft dehiscence, recurrence, or any other complication. Results: The mean age of the patients was 56.96 ± 11.51 years (range 35-81 years). There were 18 females (75%) and 6 males (25%). The following complications were noted: granuloma in three eyes (12.5 %), overriding graft onto the cornea in three eyes (4.17%), and recurrence in one eye (4.17%). No other complications were noted. Average surgical time was 16 ± 2 minutes. Conclusion: Sutureless and glue-free limbal conjunctival autografting is a treatment modality for primary nasal pterygium with no additional cost and has only one recurrence case in 24 cases.
{"title":"Primary nasal pterygium excision with sutureless and glue-free technique of conjunctival autograft","authors":"Rini Kusumawar Dhany","doi":"10.35119/asjoo.v16i3.494","DOIUrl":"https://doi.org/10.35119/asjoo.v16i3.494","url":null,"abstract":"Aim: To evaluate the efficacy and complication of sutureless and glue-free conjunctival autograft for the management of primary pterygium over a period of one year. \u0000Methods: Prospective, interventional, hospital-based study. Twenty-four eyes of 24 patients with primary nasal pterygium were graded, and excision was performed by a single surgeon. To prevent recurrence, a free conjunctival autograft was taken from the superior quadrant from the same eye and the bare sclera was covered without the use of sutures or fibrin glue, allowing natural autologous coagulum of the recipient bed to act as a bioadhesive. The eye was patched for 24 hours. Postoperatively, patients were put on topical eye drops (polymixin 0.5%, neomycin 0.5%, and dexamethasone 1%) four times daily for four weeks, and oral antibiotics and methyl prednisolone 3x4 mg per day for 5 days. Patients were followed up postoperatively on day 1, 1 week, 6 weeks, 6 months, and 12 months. They were examined for haemorrhage, wound gape, graft shrinkage, granuloma, graft dehiscence, recurrence, or any other complication. \u0000Results: The mean age of the patients was 56.96 ± 11.51 years (range 35-81 years). There were 18 females (75%) and 6 males (25%). The following complications were noted: granuloma in three eyes (12.5 %), overriding graft onto the cornea in three eyes (4.17%), and recurrence in one eye (4.17%). No other complications were noted. Average surgical time was 16 ± 2 minutes. \u0000Conclusion: Sutureless and glue-free limbal conjunctival autografting is a treatment modality for primary nasal pterygium with no additional cost and has only one recurrence case in 24 cases.","PeriodicalId":39864,"journal":{"name":"Asian Journal of Ophthalmology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42852762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-01-17DOI: 10.35119/ASJOO.V16I3.421
C. Chung, E. Yiu
A 12-year-old boy with suprasellar germinoma complicated by hydrocephalus was found to have dorsal midbrain syndrome and bilateral compressive optic neuropathy. Following a third ventricular neuroendoscopic biopsy and the initiation of chemotherapy, a follow-up magnetic resonance imaging scan of the brain showed significant regression of the tumor with resolution of hydrocephalus. On smooth pursuit, there was significant improvement in upgaze. However, light-near dissociation of his pupillary defect was persistent. Fundal examination showed persistent temporal pallor of the optic discs bilaterally, associated with a suboptimal best-corrected visual acuity of 20/40 and bilateral centrocecal scotoma.The differential recovery of neuronal function following relief of compression is poorly understood. In this case, both the optic nerve and pretectal axonal fibers responsible for pupillary reflex, with their neuronal cell bodies residing outside the direct compressive site at the midbrain, showed poor functional recovery. However, relief of pressure at the rostral interstitial medial longitudinal fasciculus and posterior commissure nuclear complexes resulted in significant clinical improvement in upgaze. This case suggests that, for neurons, axons are apparently more susceptible to pressure than cell bodies. The predominant transmission of nerve impulses takes place through the length of axons, and thus is more sensitive to pressure changes, with the associated microvascular compromise and demyelination.
{"title":"Is there variable neuronal susceptibility to compression?","authors":"C. Chung, E. Yiu","doi":"10.35119/ASJOO.V16I3.421","DOIUrl":"https://doi.org/10.35119/ASJOO.V16I3.421","url":null,"abstract":"A 12-year-old boy with suprasellar germinoma complicated by hydrocephalus was found to have dorsal midbrain syndrome and bilateral compressive optic neuropathy. Following a third ventricular neuroendoscopic biopsy and the initiation of chemotherapy, a follow-up magnetic resonance imaging scan of the brain showed significant regression of the tumor with resolution of hydrocephalus. On smooth pursuit, there was significant improvement in upgaze. However, light-near dissociation of his pupillary defect was persistent. Fundal examination showed persistent temporal pallor of the optic discs bilaterally, associated with a suboptimal best-corrected visual acuity of 20/40 and bilateral centrocecal scotoma.The differential recovery of neuronal function following relief of compression is poorly understood. In this case, both the optic nerve and pretectal axonal fibers responsible for pupillary reflex, with their neuronal cell bodies residing outside the direct compressive site at the midbrain, showed poor functional recovery. However, relief of pressure at the rostral interstitial medial longitudinal fasciculus and posterior commissure nuclear complexes resulted in significant clinical improvement in upgaze. \u0000This case suggests that, for neurons, axons are apparently more susceptible to pressure than cell bodies. The predominant transmission of nerve impulses takes place through the length of axons, and thus is more sensitive to pressure changes, with the associated microvascular compromise and demyelination. \u0000 \u0000 ","PeriodicalId":39864,"journal":{"name":"Asian Journal of Ophthalmology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44215471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-01-17DOI: 10.35119/asjoo.v16i3.511
Nur Reza Mohamad Noh, Geng-Yi Yong, Siew-Ting Lee, Kui-Feng Low, S. Pan
Purpose: To compare pterygium surgery with fibrin glue autografts and sutured autografts in terms of length of surgery time and postoperative patient satisfaction. Methods: All pterygium operations performed at Sibu Hospital (Sarawak, Malaysia) between October 1, 2012 and September 30, 2013 were included. Results: Eighty-one cases were included in the study. The fibrin glue group and suture group had 33 and 48 cases, respectively. The mean age of the patients was 50.56 (SD: 7.61). The fibrin glue group had a shorter mean duration of surgery (17.18 minutes, SD: 10.66) compared to the suture group (22.60 minutes, SD: 12.88) (P = 0.05). Patient satisfaction at first week review was 93.9% for the fibrin glue group and 75.0% for the suture group (P = 0.027, OR 5.2 [95%CI: 1.1, 24.9]). Patient satisfaction at sixth week review was 97.0% for the fibrin glue group and 77.1% for the suture group (P = 0.023, OR 9.5 [95%CI: 1.2, 77.8]). There was no serious adverse event in this study population. Conclusion: Fibrin glue has shorter mean duration of surgery and significantly higher patient satisfaction at first week and sixth week post-pterygium surgery compared to the suture technique.
{"title":"Patient satisfaction of pterygium surgery using fibrin glue versus suture autograft","authors":"Nur Reza Mohamad Noh, Geng-Yi Yong, Siew-Ting Lee, Kui-Feng Low, S. Pan","doi":"10.35119/asjoo.v16i3.511","DOIUrl":"https://doi.org/10.35119/asjoo.v16i3.511","url":null,"abstract":"Purpose: To compare pterygium surgery with fibrin glue autografts and sutured autografts in terms of length of surgery time and postoperative patient satisfaction. \u0000Methods: All pterygium operations performed at Sibu Hospital (Sarawak, Malaysia) between October 1, 2012 and September 30, 2013 were included. \u0000Results: Eighty-one cases were included in the study. The fibrin glue group and suture group had 33 and 48 cases, respectively. The mean age of the patients was 50.56 (SD: 7.61). The fibrin glue group had a shorter mean duration of surgery (17.18 minutes, SD: 10.66) compared to the suture group (22.60 minutes, SD: 12.88) (P = 0.05). Patient satisfaction at first week review was 93.9% for the fibrin glue group and 75.0% for the suture group (P = 0.027, OR 5.2 [95%CI: 1.1, 24.9]). Patient satisfaction at sixth week review was 97.0% for the fibrin glue group and 77.1% for the suture group (P = 0.023, OR 9.5 [95%CI: 1.2, 77.8]). There was no serious adverse event in this study population. \u0000Conclusion: Fibrin glue has shorter mean duration of surgery and significantly higher patient satisfaction at first week and sixth week post-pterygium surgery compared to the suture technique.","PeriodicalId":39864,"journal":{"name":"Asian Journal of Ophthalmology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41617397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-01-17DOI: 10.35119/asjoo.v16i3.395
A. Srirampur, P. Garg, Gangaprasad Amula
We report a rare presentation of herpetic stromal keratitis reactivation in a 43-yearold patient who underwent LASIK previously and presented with complaints of photophobia, pain, and redness. On examination, mild congestion was noted with deep-seated, ring-like infiltrate under the LASIK flap with some amount of scarring that was initially confused with diffuse lamellar keratitis. A detailed repeated history led to diagnosing herpetic keratitis reactivation that with timely treatment of antivirals and steroids helped us to achieve a good anatomic and visual outcome for the patient.
{"title":"Presumed Herpes simplex virus reactivation following LASIK mimicking diffuse lamellar keratitis","authors":"A. Srirampur, P. Garg, Gangaprasad Amula","doi":"10.35119/asjoo.v16i3.395","DOIUrl":"https://doi.org/10.35119/asjoo.v16i3.395","url":null,"abstract":"We report a rare presentation of herpetic stromal keratitis reactivation in a 43-yearold patient who underwent LASIK previously and presented with complaints of photophobia, pain, and redness. On examination, mild congestion was noted with deep-seated, ring-like infiltrate under the LASIK flap with some amount of scarring that was initially confused with diffuse lamellar keratitis. A detailed repeated history led to diagnosing herpetic keratitis reactivation that with timely treatment of antivirals and steroids helped us to achieve a good anatomic and visual outcome for the patient.","PeriodicalId":39864,"journal":{"name":"Asian Journal of Ophthalmology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48945582","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-01-09DOI: 10.35119/asjoo.v16i3.385
T. Natung, P. K. Goswami, Avonuo Keditsu, Wakaru Shullai
Purpose: To compare the intraocular pressure (IOP) and central corneal thickness (CCT) of non-glaucomatous North-East (NE) Indian tribals and general Indians. Materials and methods: In a prospective, cross-sectional study, the IOP and CCT of non-glaucomatous NE Indian tribals (n = 50) and non-glaucomatous general Indians (n = 50) were compared. Glaucoma was ruled out by history, detailed ocular examinations, and investigations. Results: There was very good correlation between the CCT and IOP values of right and left eyes (p = 0.940 and 0.847, respectively). The difference in the IOP values in the two groups was not statistically significant (p = 0.312 for Oculus Dexter [OD], p = 0.400 for Oculus Sinister [OS]). Similarly, the difference in the CCT values in the two groups was not statistically significant (p = 0.736 for OD and 0.613 for OS). The mean CCT and IOP OD for the whole population was 530.50 ± 35.42 μm and 13.80 ± 2.760 mmHg, respectively. By linear regression analysis, the IOP OD of the whole population had good correlation with CCT OD of the whole population (adjusted r2 = 0.084, p = 0.002), but not with age (adjusted r2=0.000, p=0.314) and sex (adjusted r2 = 0.010, p = 0.163). Similarly, CCT OD for the whole population did not have good correlation with age (adjusted r2 = -0.009, p = 0.762) and sex (adjusted r2 = -0.007, p = 0.603). Conclusions: In this study of individuals with normal corneas and without glaucoma, no racial variation was found in the CCT and IOP values of the two groups. The IOP OD of whole population had good correlation with CCT, but not with age and sex. There was good correlation between OD and OS values of IOP and CCT.
{"title":"Comparison of intraocular pressure and central corneal thickness in non-glaucomatous North- East Indian tribals versus general Indians","authors":"T. Natung, P. K. Goswami, Avonuo Keditsu, Wakaru Shullai","doi":"10.35119/asjoo.v16i3.385","DOIUrl":"https://doi.org/10.35119/asjoo.v16i3.385","url":null,"abstract":"Purpose: To compare the intraocular pressure (IOP) and central corneal thickness (CCT) of non-glaucomatous North-East (NE) Indian tribals and general Indians. \u0000Materials and methods: In a prospective, cross-sectional study, the IOP and CCT of non-glaucomatous NE Indian tribals (n = 50) and non-glaucomatous general Indians (n = 50) were compared. Glaucoma was ruled out by history, detailed ocular examinations, and investigations. \u0000Results: There was very good correlation between the CCT and IOP values of right and left eyes (p = 0.940 and 0.847, respectively). The difference in the IOP values in the two groups was not statistically significant (p = 0.312 for Oculus Dexter [OD], p = 0.400 for Oculus Sinister [OS]). Similarly, the difference in the CCT values in the two groups was not statistically significant (p = 0.736 for OD and 0.613 for OS). The mean CCT and IOP OD for the whole population was 530.50 ± 35.42 μm and 13.80 ± 2.760 mmHg, respectively. By linear regression analysis, the IOP OD of the whole population had good correlation with CCT OD of the whole population (adjusted r2 = 0.084, p = 0.002), but not with age (adjusted r2=0.000, p=0.314) and sex (adjusted r2 = 0.010, p = 0.163). Similarly, CCT OD for the whole population did not have good correlation with age (adjusted r2 = -0.009, p = 0.762) and sex (adjusted r2 = -0.007, p = 0.603). \u0000Conclusions: In this study of individuals with normal corneas and without glaucoma, no racial variation was found in the CCT and IOP values of the two groups. The IOP OD of whole population had good correlation with CCT, but not with age and sex. There was good correlation between OD and OS values of IOP and CCT.","PeriodicalId":39864,"journal":{"name":"Asian Journal of Ophthalmology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49553502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-11-21DOI: 10.35119/asjoo.v16i2.353
Krishna A. Rao, R. Chandra, L. Rao, S. Shailaja, M. Hazarika
Aim: To measure macular thickness by optical coherence tomography (OCT) in various grades of diabetic retinopathy with no clinically significant macular edema (CSME) and its comparison with non-diabetics. Design: Prospective cross–sectional study. Methods: Macular thickness was measured by OCT in 72 healthy volunteers (107 control eyes), 45 patients with mild and moderate non-proliferative diabetic retinopathy (NPDR) (78 eyes) and 37 patients with severe NPDR and proliferative diabetic retinopathy (PDR) (66 eyes). Patients with diabetic macular edema (DME) as assessed by stereoscopic evaluation or photographs were excluded. One-way ANOVA test to compare the mean thickness and Tukey's test for multiple comparison between groups were used. Results: Central subfield thickness (CST) was 238.57 ± 25.077 µm, 251.22 ± 24.649 µm, and 270.45 ± 28.956 µm in the three groups respectively. As the severity of retinopathy increased, the macular thickness significantly increased (p = < 0.001) in all the nine zones on OCT. There was a significant increase in CST noted in all the grades of retinopathy when compared with non-diabetics (p = 0.004, p = < 0.0001). No significant difference in macular thickness was noted between genders, irrespective of their groups (p = 0.72), or between the three groups in all the nine zones (p = 0.609). Conclusion: There is a significant increase in CST in all grades of retinopathy, as well as with increasing severity of retinopathy when compared to non-diabetics. This warrants the need to obtain OCT measurements even in patients with moderate NPDR without CSME to rule out subclinical DME.
{"title":"Macular thickness in diabetic retinopathy without clinically significant macular edema","authors":"Krishna A. Rao, R. Chandra, L. Rao, S. Shailaja, M. Hazarika","doi":"10.35119/asjoo.v16i2.353","DOIUrl":"https://doi.org/10.35119/asjoo.v16i2.353","url":null,"abstract":"Aim: To measure macular thickness by optical coherence tomography (OCT) in various grades of diabetic retinopathy with no clinically significant macular edema (CSME) and its comparison with non-diabetics. \u0000Design: Prospective cross–sectional study. \u0000Methods: Macular thickness was measured by OCT in 72 healthy volunteers (107 control eyes), 45 patients with mild and moderate non-proliferative diabetic retinopathy (NPDR) (78 eyes) and 37 patients with severe NPDR and proliferative diabetic retinopathy (PDR) (66 eyes). Patients with diabetic macular edema (DME) as assessed by stereoscopic evaluation or photographs were excluded. One-way ANOVA test to compare the mean thickness and Tukey's test for multiple comparison between groups were used. \u0000Results: Central subfield thickness (CST) was 238.57 ± 25.077 µm, 251.22 ± 24.649 µm, and 270.45 ± 28.956 µm in the three groups respectively. As the severity of retinopathy increased, the macular thickness significantly increased (p = < 0.001) in all the nine zones on OCT. There was a significant increase in CST noted in all the grades of retinopathy when compared with non-diabetics (p = 0.004, p = < 0.0001). No significant difference in macular thickness was noted between genders, irrespective of their groups (p = 0.72), or between the three groups in all the nine zones (p = 0.609). \u0000Conclusion: There is a significant increase in CST in all grades of retinopathy, as well as with increasing severity of retinopathy when compared to non-diabetics. This warrants the need to obtain OCT measurements even in patients with moderate NPDR without CSME to rule out subclinical DME.","PeriodicalId":39864,"journal":{"name":"Asian Journal of Ophthalmology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41368999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-11-21DOI: 10.35119/asjoo.v16i2.382
V. Pai, S. Reddy
Aim: To compare the prevalence of ocular surface disease (OSD) in patients using antiglaucoma medications vs normal subjects. Design: Prospective observational study. Methods: A total of 94 patients with glaucoma on topical medications were included in the study group. Age- and gender-matched normal subjects (n = 94) formed the control group. They were assessed for OSD using ocular surface disease index (OSDI) questionnaire, tear break-up time (TBUT), Lissamine green staining, and Schirmer’s test. Results: The prevalence of OSD was significantly more in the study group (72.4%) when compared to controls (44.6%) using the OSDI questionnaire. Schirmer’s test showed 84% patients had decreased tear production in the study group vs 53% in controls. TBUT was abnormal in 67.1% of the study group and of 47.8% controls. Lissamine green staining was positive in 36.2% of patients in the study group and 31.8% of controls. Conclusion: OSD was more common in patients using intraocular pressure (IOP)-lowering drugs than in controls. Long-term therapy and multiple medications were associated with severe OSD.
{"title":"Prevalence of ocular surface disease in patients with glaucoma on topical medications","authors":"V. Pai, S. Reddy","doi":"10.35119/asjoo.v16i2.382","DOIUrl":"https://doi.org/10.35119/asjoo.v16i2.382","url":null,"abstract":"Aim: To compare the prevalence of ocular surface disease (OSD) in patients using antiglaucoma medications vs normal subjects. \u0000Design: Prospective observational study. \u0000Methods: A total of 94 patients with glaucoma on topical medications were included in the study group. Age- and gender-matched normal subjects (n = 94) formed the control group. They were assessed for OSD using ocular surface disease index (OSDI) questionnaire, tear break-up time (TBUT), Lissamine green staining, and Schirmer’s test. \u0000Results: The prevalence of OSD was significantly more in the study group (72.4%) when compared to controls (44.6%) using the OSDI questionnaire. Schirmer’s test showed 84% patients had decreased tear production in the study group vs 53% in controls. TBUT was abnormal in 67.1% of the study group and of 47.8% controls. Lissamine green staining was positive in 36.2% of patients in the study group and 31.8% of controls. \u0000Conclusion: OSD was more common in patients using intraocular pressure (IOP)-lowering drugs than in controls. Long-term therapy and multiple medications were associated with severe OSD.","PeriodicalId":39864,"journal":{"name":"Asian Journal of Ophthalmology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47825380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-11-21DOI: 10.35119/asjoo.v16i2.367
Vijaya Anandan, Rekha Srinivasan, R. Asokan, R. George
Aim: To compare the anterior chamber volume measurements obtained with Pentacam and derived from anterior segment optical coherence tomography. Design: Cross-sectional study. Methods: We included normal subjects who underwent a comprehensive eye examination including refraction, keratometry, Goldmann applanation tonometry, gonioscopy, anterior segment optical coherence tomography (AS-OCT) (Carl Zeiss Meditec Inc.; Dublin, CA, USA) and Pentacam (Oculus Inc.; Lynnwood, WA, USA). Fifty scans were selected for Pentacam and 12 images were selected for calculation of anterior chamber volume. Only the right eye was considered for analysis. Results: One-hundred and nineteen eyes of 119 subjects were included for analysis. The mean age of the subjects was 42.58 ± 13.15 years, of which 74 were female and 45 were male. The mean anterior chamber volume measured using AS-OCT was 119.17 ± 26.56 mm3 and with Pentacam was 131.29 ± 34.26 mm3. The comparison of means between the two modalities was statistically significant (t = -8.857, Mean Difference (MD) = 12.11, 95% CI: (4.29, 19.95), p = 0.003). Bland-Altman plot showed poor agreement between the chamber volume measurements obtained by Pentacam and AS-OCT with MD of 12.1 mm3 (95 % CI: 41.4 to -17.1) and intra-class correlation between the two instruments was 0.94 (95% CI: 0.91, 0.96) (p < 0.0001). Conclusion: The anterior chamber volume can be measured using Pentacam as well as AS-OCT since these measurements were reliable. However, these measurements were not interchangeable due to poor levels of agreement.
{"title":"Evaluation of anterior chamber volume using Pentacam and anterior segment optical coherence tomography among normal subjects","authors":"Vijaya Anandan, Rekha Srinivasan, R. Asokan, R. George","doi":"10.35119/asjoo.v16i2.367","DOIUrl":"https://doi.org/10.35119/asjoo.v16i2.367","url":null,"abstract":"Aim: To compare the anterior chamber volume measurements obtained with Pentacam and derived from anterior segment optical coherence tomography. \u0000Design: Cross-sectional study. \u0000Methods: We included normal subjects who underwent a comprehensive eye examination including refraction, keratometry, Goldmann applanation tonometry, gonioscopy, anterior segment optical coherence tomography (AS-OCT) (Carl Zeiss Meditec Inc.; Dublin, CA, USA) and Pentacam (Oculus Inc.; Lynnwood, WA, USA). Fifty scans were selected for Pentacam and 12 images were selected for calculation of anterior chamber volume. Only the right eye was considered for analysis. \u0000Results: One-hundred and nineteen eyes of 119 subjects were included for analysis. The mean age of the subjects was 42.58 ± 13.15 years, of which 74 were female and 45 were male. The mean anterior chamber volume measured using AS-OCT was 119.17 ± 26.56 mm3 and with Pentacam was 131.29 ± 34.26 mm3. The comparison of means between the two modalities was statistically significant (t = -8.857, Mean Difference (MD) = 12.11, 95% CI: (4.29, 19.95), p = 0.003). Bland-Altman plot showed poor agreement between the chamber volume measurements obtained by Pentacam and AS-OCT with MD of 12.1 mm3 (95 % CI: 41.4 to -17.1) and intra-class correlation between the two instruments was 0.94 (95% CI: 0.91, 0.96) (p < 0.0001). \u0000Conclusion: The anterior chamber volume can be measured using Pentacam as well as AS-OCT since these measurements were reliable. However, these measurements were not interchangeable due to poor levels of agreement.","PeriodicalId":39864,"journal":{"name":"Asian Journal of Ophthalmology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46736940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-11-21DOI: 10.35119/asjoo.v16i2.375
K. Oh, A. Zahidin, Umi Kalthum Md Noh, Safinaz Mohd Khialdin, G. Ooi, K. Then
Purpose: To report a case series of seven eyes (six patients) with severe limbal stem cell failure who underwent cultivated oral mucosa epithelium transplantation (COMET) in preparation for corneal transplant surgery and assess the change in visual acuity postoperatively. Design: Case series. Methods: A retrospective analysis of an interventional case series of six patients with severe limbal stem cell deficiency who underwent COMET between 2012 and 2015 was performed. Six eyes had COMET followed by corneal transplant, and one eye had corneal transplant preceding COMET. The change in the visual acuity after operation was evaluated. Results: A total of six patients with seven eyes were studied. All of them had severe ocular surface disease with limbal stem cell deficiency (LSCD) secondary to chemical injury (five eyes), SJS (one eye), and severe ocular rosacea (one eye). Four eyes had improvements in visual acuity, two of which achieved best corrected visual acuity (BCVA) of 6/12. Conclusion: The use of COMET helps to optimize the ocular surface in severe LSCD for further corneal transplant surgeries. It has helped to improve the graft uptake and subsequent visual improvement, especially in chronic chemical burn cases.
{"title":"Case series of cultivated oral mucosa epithelium transplantation for limbal stem cell failure","authors":"K. Oh, A. Zahidin, Umi Kalthum Md Noh, Safinaz Mohd Khialdin, G. Ooi, K. Then","doi":"10.35119/asjoo.v16i2.375","DOIUrl":"https://doi.org/10.35119/asjoo.v16i2.375","url":null,"abstract":"Purpose: To report a case series of seven eyes (six patients) with severe limbal stem cell failure who underwent cultivated oral mucosa epithelium transplantation (COMET) in preparation for corneal transplant surgery and assess the change in visual acuity postoperatively. \u0000Design: Case series. \u0000Methods: A retrospective analysis of an interventional case series of six patients with severe limbal stem cell deficiency who underwent COMET between 2012 and 2015 was performed. Six eyes had COMET followed by corneal transplant, and one eye had corneal transplant preceding COMET. The change in the visual acuity after operation was evaluated. \u0000Results: A total of six patients with seven eyes were studied. All of them had severe ocular surface disease with limbal stem cell deficiency (LSCD) secondary to chemical injury (five eyes), SJS (one eye), and severe ocular rosacea (one eye). Four eyes had improvements in visual acuity, two of which achieved best corrected visual acuity (BCVA) of 6/12. \u0000Conclusion: The use of COMET helps to optimize the ocular surface in severe LSCD for further corneal transplant surgeries. It has helped to improve the graft uptake and subsequent visual improvement, especially in chronic chemical burn cases. \u0000 ","PeriodicalId":39864,"journal":{"name":"Asian Journal of Ophthalmology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43139425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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