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Orbital cellulitis following Caldwell Luc procedure for maxillary sinusitis leading to a rare complication of central retinal artery occlusion 上颌窦炎的Caldwell Luc手术后眼眶蜂窝织炎导致视网膜中央动脉闭塞的罕见并发症
Q4 Medicine Pub Date : 2020-01-17 DOI: 10.35119/ASJOO.V17I1.454
D. Mahajan, G. Sharma, R. Tuli
Posterior orbital cellulitis is a clinical syndrome in which early severe visual loss overshadows or precedes accompanying inflammatory orbital signs. It is an ocular emergency that can threaten life and vision. Central retinal artery occlusion (CRAO) is a very rare condition leading to sudden onset of decreased vision and can even progress to blindness. We report a case of orbital cellulitis following Caldwell Luc surgery in a middle-aged diabetic woman, resulting in the rare complication of CRAO, leading to blindness in her right eye. The development of retinal artery occlusion after orbital cellulitis has not been well documented in literature. A quick diagnosis and close monitoring following sinus surgery is therefore needed to prevent such rare complications to happen.
眼眶后蜂窝组织炎是一种临床综合征,早期严重视力丧失掩盖或先于伴随的炎症性眼眶体征。这是一种眼部紧急情况,可能威胁生命和视力。视网膜中央动脉阻塞(CRAO)是一种非常罕见的情况,会导致视力突然下降,甚至可能发展为失明。我们报告了一例中年糖尿病妇女在Caldwell Luc手术后发生眼眶蜂窝组织炎,导致罕见的CRAO并发症,导致右眼失明。眼眶蜂窝组织炎后视网膜动脉闭塞的发展在文献中没有很好的记录。因此,需要在鼻窦手术后进行快速诊断和密切监测,以防止此类罕见并发症的发生。
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引用次数: 0
Adult gonococcal keratoconjunctivitis: early detection is key 成人淋球菌性角结膜炎:早期发现是关键
Q4 Medicine Pub Date : 2020-01-17 DOI: 10.35119/ASJOO.V17I1.444
Daniel Lai, K. Ong
We describe a case of a 52-year-old male presenting with severe mucopurulent conjunctivitis of the right eye. Corneal ulceration and associated anterior chamber activity was noted later in the course of the disease. Neisseria gonorrhoeae was positive on polymerase chain reaction (PCR) testing earlier than traditional microscopy and culture. He was successfully treated with ceftriaxone 500 mg intravenously and azithromycin 1 g orally as single doses in addition to ofloxacin ophthalmic solution 0.3% hourly to the right eye. This case highlights the need to consider the possibility of gonococcus in cases of suspected bacterial conjunctivitis, careful monitoring for corneal involvement and the importance of early detection with PCR.
我们描述了一个52岁的男性表现为严重的粘液化脓性结膜炎的右眼。角膜溃疡和相关的前房活动在病程的后期被注意到。淋病奈瑟菌聚合酶链反应(PCR)检测阳性早于传统镜检和培养。在右眼滴注氧氟沙星眼液0.3% /小时的基础上,静脉滴注头孢曲松500 mg,单次口服阿奇霉素1 g,治疗成功。本病例强调了在疑似细菌性结膜炎病例中考虑淋球菌的可能性,仔细监测角膜受累情况以及PCR早期检测的重要性。
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引用次数: 0
Intermediate-term outcome of placement of Baerveldt glaucoma implant for refractory glaucoma in a Malaysian population 在马来西亚人群中放置Baerveldt青光眼植入物治疗难治性青光眼的中期结果
Q4 Medicine Pub Date : 2020-01-17 DOI: 10.35119/ASJOO.V17I1.500
C. Fang, Seng Kheong Fang
Objective: To report baseline characteristics and surgical outcomes of placement of Baerveldt glaucoma implant (BGI) in Asian eyes with considerably elevated intraocular pressure (IOP) despite maximal medical therapy. Design: Retrospective case series of surgical cases from a single surgeon. Retrospective review of medical records of last clinic visits. Participants: One hundred and ninety-seven eyes of patients underwent placement of 350-mm2 Baerveldt implant. Methods: The medical records of consecutive patients who underwent placement of a Baerveldt 350-mm2 glaucoma drainage device (GDD) at the International Specialist Eye Centre from 2007 to 2014 were reviewed. Patients with a minimum 1-year follow-up were included. Baseline characteristics, pre-operative and post-operative IOP, number of glaucoma medications, visual acuity (VA) and complications were recorded. The pre-operative IOP is compared with the IOP at 1, 2, 3 and 5 years. Measures: The IOP, VA, supplemental medical therapy, complications and success and failures were recorded. Results: One hundred and ninety-seven patients were followed up at 1-year post-operation, 157 patients at 2 years, 120 at 3 years and 37 at 5 years. The mean baseline IOP of 29.2 ± 10.6 mmHg was significantly reduced at all time points post-operatively. Mean number of glaucoma medications was significantly lower at last follow-up than pre-operatively (1.8 vs. 2.7). Conclusions: Placement of GDDs effectively reduces IOP without much long-term complication and may be useful in glaucomatous eyes with considerably elevated pre-operative IOP not well controlled with maximal medical therapy in the Asian population.
目的:报道在亚洲眼内眼压(IOP)明显升高的情况下,尽管进行了最大限度的药物治疗,Baerveldt青光眼植入物(BGI)的基线特征和手术结果。设计:回顾性研究来自同一位外科医生的一系列手术病例。最后一次门诊病历的回顾性分析。实验对象:197眼患者行350-mm2 Baerveldt植入。方法:回顾2007年至2014年在国际专科眼科中心连续放置Baerveldt 350-mm2青光眼引流装置(GDD)患者的病历。患者至少随访1年。记录基线特征、术前、术后IOP、青光眼用药次数、视力(VA)及并发症。将术前IOP与1、2、3、5年时的IOP进行比较。措施:记录IOP、VA、辅助药物治疗、并发症及成败情况。结果:术后1年随访197例,2年随访157例,3年随访120例,5年随访37例。术后各时间点平均基线眼压(29.2±10.6 mmHg)均显著降低。最后一次随访时,青光眼药物的平均使用次数明显低于术前(1.8 vs. 2.7)。结论:植入式GDDs可有效降低IOP,且无长期并发症,对亚洲人群中术前IOP升高且药物治疗效果不佳的青光眼患者可能有用。
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引用次数: 0
Benzalkonium chloride corneal toxicity post-cataract surgery 苯扎氯铵对白内障术后角膜的毒性
Q4 Medicine Pub Date : 2020-01-17 DOI: 10.35119/ASJOO.V17I1.620
K. Ong, L. Ong
Two patients with presumed benzalkonium chloride (BAK) corneal toxicity after routine cataract surgery are presented. Patient 1 had corneal stroma and Descemet’s membrane folds. Patient 2 had moderate superficial punctate epithelial erosions (SPEE). They were on Chlorsig, Maxidex, and Acular eye drops tds postoperatively. The corneas of these two patients improved when BAK was removed or minimized from the postoperative eye drop regimen. Two vials of 1 ml dexamethasone 4mg/ml for injection were added to Chlorsig 10 ml bottle to substitute for Maxidex eye drops. BAK toxicity should be suspected when the cornea is not as clear as expected postoperatively. A practical way to eliminate BAK from postoperative eye drops is described, and would be useful until pharmaceuticals mass-produce BAK-free steroid eye drops economically.
介绍了两名常规白内障手术后出现苯扎氯铵(BAK)角膜毒性的患者。患者1有角膜基质和后弹力膜折叠。患者2有中度浅表点状上皮侵蚀(SPEE)。术后分别使用氯西格、Maxidex和Acular滴眼液。当BAK从术后滴眼方案中去除或最小化时,这两名患者的角膜得到改善。在Chlorsig 10ml瓶中加入两瓶1ml地塞米松4mg/ml注射液,以代替Maxidex滴眼液。当术后角膜不如预期清晰时,应怀疑BAK毒性。描述了一种从术后滴眼液中消除BAK的实用方法,该方法在药物经济地大规模生产不含BAK的类固醇滴眼液之前是有用的。
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引用次数: 0
Evaluating the difference between autorefraction and subjective refraction may guide “fudge factor” for IOL power selection for cataract surgery after previous LASIK 评估自体屈光和主观屈光的差异,可以指导既往LASIK术后白内障手术人工晶状体度数选择的“模糊因子”
Q4 Medicine Pub Date : 2020-01-17 DOI: 10.35119/ASJOO.V17I1.576
K. Ong, Daisy Y. Shu
We propose a method to estimate “fudge factor” in the selection of IOL power for post-myopic LASIK patients undergoing cataract surgery by considering the difference between subjective refraction (SR) and autorefraction (AR) and to also compare the predictability of two popular regression formulae: SRK-T and Haigis.
我们提出了一种方法,通过考虑主观屈光(SR)和自身屈光(AR)的差异来估计近视后LASIK患者选择IOL度数时的“蒙混因子”,并比较了两种流行的回归公式:SRK-T和Haigis的可预测性。
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引用次数: 0
Macular buckle with Morin–Devin T implant for pathological myopia with macular hole Morin-Devin T植入黄斑带扣治疗病理性近视黄斑裂孔
Q4 Medicine Pub Date : 2020-01-17 DOI: 10.35119/ASJOO.V17I1.463
A. Anand, Lalit Agarwal, N. Agrawal, A. Anand
Introduction: Pathological myopia is commonly associated with myopic traction maculopathy, which includes foveoschisis, foveal retinal detachment, macular hole (MH) and/or macular detachment (MD). Macular buckling is a rarely practiced extraocular surgical modality these days. The purpose of this study was to investigate the efficacy of primary buckling with Morin–Devin T implant for MD with MH and posterior staphyloma. Case description: A 52-year-old female presented with light perception vision in her right eye with posterior staphyloma, localized neurosensory detachment, and MH. She underwent primary macular buckling with Morin–Devin T implant. During the immediate postoperative day the wedge indentation was found misaligned to the fovea. A revision surgery was done after 2 weeks for repositioning of the macular wedge. Spectral domain optical coherence tomography confirmed indentation at the MH with resolution of subretinal fluid and hole closure. Her BCVA was 2/60 at 3 months postoperative and it remained the same even at 6 months of follow-up. Conclusions: Primary macular buckling can be an effective procedure in eyes with MH with detachment and posterior staphyloma with or without associated foveoschisis. Morin–Devin T implant placement is a relatively simple procedure with short surgical time and excellent outcome.
引言:病理性近视通常与近视牵引性黄斑病变有关,包括中央凹裂、中央凹视网膜脱离、黄斑裂孔(MH)和/或黄斑脱离(MD)。黄斑屈曲是目前一种罕见的眼外手术方式。本研究的目的是研究Morin–Devin T植入物一次屈曲治疗伴有MH和后葡萄肿的MD的疗效。病例描述:一名52岁女性,右眼出现光感视觉,伴有后葡萄肿、局部神经感觉脱离和MH。她接受了Morin-Devin T植入物的原发性黄斑屈曲。术后第二天发现楔形压痕与中央凹错位。两周后进行了黄斑楔复位的翻修手术。光谱域光学相干断层扫描证实了MH处的压痕,具有视网膜下液和孔闭合的分辨率。术后3个月,她的BCVA为2/60,即使在随访6个月时也保持不变。结论:原发性黄斑屈曲是治疗伴有脱离的MH和伴有或不伴有中央凹凹陷的后葡萄肿的有效方法。Morin–Devin T植入术是一种相对简单的手术方法,手术时间短,效果良好。
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引用次数: 1
Anterior segment optical coherence tomography of intrastromal corneal cysts 角膜基质内囊肿的前段光学相干断层扫描
Q4 Medicine Pub Date : 2020-01-17 DOI: 10.35119/ASJOO.V17I1.446
D. Mazumdar, Barsha Lal, R. Asokan
We report a case of six-year-old boy who presented with a progressive intracorneal cyst in the left eye. Anterior segment optical coherence tomography (AS-OCT) was performed, and it showed the location of the cyst in the corneal stroma. Its dimension was measured to be 7.09 A~ 2.12 mm. The cyst aspiration was successfully done. AS-OCT helped in the management and follow-up of the condition.
我们报告一个六岁男孩的病例,他在左眼出现进行性的角膜内囊肿。进行了前段光学相干断层扫描(AS-OCT),显示了囊肿在角膜基质中的位置。其大小为7.09A~2.12mm,成功地完成了囊肿抽吸。AS-OCT有助于病情的管理和随访。
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引用次数: 0
Prophylactic corneal cross-linking in LASIK surgery: effects on visual outcome and recovery time LASIK手术中预防性角膜交联对视力和恢复时间的影响
Q4 Medicine Pub Date : 2020-01-17 DOI: 10.35119/ASJOO.V17I1.451
D. Oh, Y. Chan, Sao-Bing Lee, J. See
Introduction: Collagen cross-linking is a useful adjunct in preventing corneal ectasia after laser-assisted in situ keratomileusis (LASIK). This study aimed to evaluate whether prophylactic cross-linking in IntraLase LASIK affects optimum visual outcome and recovery time in the immediate post-surgery period and is associated with any side effects. Methods: This was a retrospective case study on the right eyes of 100 Chinese subjects aged 18 to 40 years who underwent IntraLase LASIK. Fifty subjects who underwentcross-linking after completing LASIK (Group A) were compared with 50 subjects who did not undergo LASIK (Group B). Cases were evaluated for pre- and post-operative spherical equivalent, uncorrected distance visual acuity (UDVA) and corrected distance visual acuity (CDVA), recovery time and presence of side effects. Results: At 1 week post-LASIK, mean (SD) UDVA of Group A subjects was poorer than Group B, at 1.05 (0.19) vs 1.17 (0.19) (p = 0.036); however, there was no significant difference in CDVA (p = 0.095). By 1 month post-LASIK, differences in both UDVA and CDVA were insignificant (p = 0.055, 0.106, respectively). Mean recovery time was 2.72 (95% confidence interval [CI] = 0.64-4.7) days longer in Group A (p = 0.010), although by 1 month post-LASIK, both groups were able to achieve CDVA equal to or better than that achieved pre-LASIK. Incidence of mild inflammation and dry eyes post-LASIK was similar in both groups (p = 1.00, 0.749, respectively); no other complications were observed. Conclusion: No differences in visual outcomes at and occurrence of side effects at 1 month post-LASIK were observed between subjects who underwent cross-linking prior to refractive surgery and those who did not. However, the group that underwent cross-linking had a slightly longer mean recovery time. Our study supports prophylactic cross-linking as a safe procedure that does not affect immediate visual outcomes among the Chinese population when used in adjunct with LASIK surgery.
引言:胶原交联是预防激光原位角膜磨镶术(LASIK)后角膜扩张的有效辅助手段。本研究旨在评估LASIK术中预防性交联是否会影响术后即刻的最佳视觉效果和恢复时间,并与任何副作用有关。方法:对100例18~40岁的中国人行准分子激光原位角膜磨镶术的右眼进行回顾性病例研究。将50名完成LASIK术后未进行交叉连接的受试者(A组)与50名未进行LASIK术的受试人(B组)进行比较。评估病例的术前和术后球面当量、裸眼远视力(UDVA)和矫正远视力(CDVA)、恢复时间和是否存在副作用。结果:LASIK术后1周,A组受试者的平均UDVA(SD)低于B组,分别为1.05(0.19)和1.17(0.19)(p=0.036);然而,CDVA没有显著差异(p=0.095)。到LASIK术后1个月,UDVA和CDVA的差异不显著(分别为p=0.055和0.106)。A组的平均恢复时间延长了2.72天(95%置信区间[CI]=0.64-4.7)(p=0.010),尽管到LASIK术后1个月,两组的CDVA均达到或优于LASIK术前。LASIK术后轻度炎症和干眼的发生率在两组中相似(p分别为1.00和0.749);未观察到其他并发症。结论:LASIK术后1个月,在屈光手术前接受交叉连接的受试者和未接受交叉连接手术的受试人之间,没有观察到视觉结果和副作用发生的差异。然而,进行交联的组的平均恢复时间稍长。我们的研究支持预防性交联作为一种安全的程序,当与LASIK手术一起使用时,不会影响中国人群的即时视觉结果。
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引用次数: 0
SITA standard testing with Humphrey visual field analyzer versus full threshold testing with frequency doubling perimetry: a comparison of patient preference and perception Humphrey视野分析仪SITA标准测试与倍频视野全阈值测试:患者偏好和感知的比较
Q4 Medicine Pub Date : 2020-01-17 DOI: 10.35119/ASJOO.V17I1.447
N. S. K. Meethal, V. Lokapavani, R. Asokan, L. Vijaya, R. George
Purpose: To compare patient preference for Swedish Interactive Threshold Algorithm (SITA) standard 24-2 protocol in Humphrey visual field analyzer (HVF) and full threshold N-30 protocol in frequency doubling perimetry (FDP) by primarily evaluating their perception about the test procedure and test targets along with surveying the factors that influence the patient concentration during perimetry and elements that determine the level of perimetry task difficulty. Methods: This study enrolled a subset of subjects from the Chennai Glaucoma Study. Each subject underwent a comprehensive ophthalmic examination after which they were randomly allocated to perform HVF and FDP with a 30-minute interval between the two procedures. SITA standard 24-2 protocol in HVF and full threshold N-30 protocol in FDP were used. This was followed by the administration of a questionnaire that mainly assessed the components such as (a) the patient preference for test procedure and test targets, (b) the factors influencing the patient concentration during perimetry performance, and (c) the impression about the level of perimetry task difficulty. The patient responses from the survey for each of the subcategories were obtained and analyzed using Chi-square test. Results: A total of 42 subjects with a mean age of 59.7 (SD 9.7) years were included, among which 18 (42.86%) were male and 24 (57.14%) were female. Thirty-two (76.19%) subjects felt both FDP and HVF were easy to perform, eight subjects (19.05%) felt that both perimetry techniques were difficult to perform, and two subjects (4.76%) found FDP procedure was easier than HVF, whereas the distribution was not statistically significant (Chi-square, p = 0.7). Pressing the button as a response to peripheral stimulus perception and inability to maintain steady central fixation for prolonged duration were the most commonly reported factors that influenced the level of difficulty of the perimetry tasks. A dark room ambience set for performing HVF was preferred by 32 (76.20%) subjects. Conclusion: There was no significant difference in the patient preference for test procedure and peripheral test targets. A black central fixation as in FDP and dark room ambience set for HVF were preferred.
目的:比较患者对Humphrey视野分析仪(HVF)中的瑞典交互式阈值算法(SITA)标准24-2方案和倍频视野计(FDP)中的全阈值N-30方案的偏好,主要评估患者对测试程序和测试目标的感知,并调查影响患者视野计中注意力的因素以及决定视野测量任务难度水平的元素。方法:本研究纳入了金奈青光眼研究的一部分受试者。每个受试者都接受了全面的眼科检查,之后他们被随机分配进行HVF和FDP,两次手术间隔30分钟。HVF中使用SITA标准24-2协议,FDP中使用全阈值N-30协议。随后进行了问卷调查,主要评估了以下组成部分,如(a)患者对测试程序和测试目标的偏好,(b)影响患者在视野测量过程中注意力的因素,以及(c)对视野测量任务难度水平的印象。使用卡方检验获得并分析每个子类别的调查患者反应。结果:共有42名受试者,平均年龄59.7岁(SD 9.7),其中18名(42.86%)为男性,24名(57.14%)为女性。32名(76.19%)受试者认为FDP和HVF都很容易执行,8名受试者(19.05%)认为两种视野测量技术都很难执行,2名受试人员(4.76%)发现FDP程序比HVF更容易,而这种分布在统计学上并不显著(卡方,p=0.7)。作为对外周刺激感知的反应按下按钮和无法长时间保持稳定的中央固定是影响视野测量任务难度的最常见因素。32名(76.20%)受试者优选设置用于进行HVF的暗室环境。结论:患者对测试程序和外周测试目标的偏好没有显著差异。首选FDP中的黑色中央固定和HVF的暗室环境设置。
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引用次数: 0
Dacryocystorhinostomy for the treatment of nasolacrimal duct obstruction: a pilot trial to assess impact on coexisting sinus symptoms 泪囊鼻腔造瘘术治疗鼻泪管阻塞:一项评估对共存鼻窦症状影响的初步试验
Q4 Medicine Pub Date : 2020-01-15 DOI: 10.35119/ASJOO.V17I1.440
Ankur N. Mehta, Wan-Ling Yi, A. Ananda, Raf Ghabriel
Purpose: To report on coexistent sinus symptoms in a population of patients who underwent endonasal dacryocystorhinostomy (DCR) surgery for nasolacrimal duct obstruction (NLDO) in a pilot study designed to test and refine methods and to estimate patient sample size for a larger multicentre randomised trial. Methods: Ninety-four consecutive patients with NLDO who underwent endonasal DCR by three surgeons in both public and private practice over a two-year period were included in this study. Questionnaires were given preceding DCR surgery and at 10 weeks post-surgery. Sinus symptoms including sinusitis, nasal congestion, hyposmia, nasal discharge, and facial pressure were assessed in the questionnaire. All subjects underwent primary endonasal DCR and all patients underwent the same post-operative regimen. Results: Questionnaire responses revealed that 48/94 (51%) patients had one or more sinus symptoms prior to DCR surgery. Ten-week post-DCR follow-up questionnaires were obtained from 77/94 (82%) patients. About 20/31 (65%) patients with one or more sinus symptoms prior to DCR surgery reported resolution of coexisting sinus symptoms by 10 weeks post-DCR surgery. Conclusion: The data from this pilot study suggest that approximately half of patients attending for NLDO have coexisting sinus symptoms. There was some loss to follow-up. This pilot study highlighted the need for a validated patient questionnaire, longer length of follow-up, control groups for surgical intervention, and use of perioperative medications. Any clinical trial designed to assess the impact of endonasal surgery on sinus symptoms would need to enrol several hundred patients in order to reach a statistically valid conclusion.
目的:在一项旨在测试和改进方法并为一项更大的多中心随机试验估计患者样本量的试点研究中,报告接受鼻内泪囊鼻腔造瘘术(DCR)治疗鼻泪管阻塞(NLDO)的患者群体中共存的鼻窦症状。方法:本研究纳入了连续94例NLDO患者,他们在两年内由三名外科医生在公共和私人诊所进行了鼻内DCR。在DCR手术前和手术后10周进行问卷调查。调查问卷中评估了鼻窦炎、鼻塞、嗅觉减退、鼻腔分泌物和面部压力等鼻窦症状。所有受试者均接受了原发性鼻内DCR,所有患者均接受了相同的术后方案。结果:问卷调查显示,48/94(51%)患者在DCR手术前有一种或多种鼻窦症状。从77/94(82%)名患者中获得DCR后10周的随访问卷。大约20/31(65%)在DCR手术前有一种或多种鼻窦症状的患者报告称,DCR手术后10周,共存的鼻窦症状得到了缓解。结论:这项初步研究的数据表明,大约一半接受NLDO治疗的患者同时存在鼻窦症状。有一些后续损失。这项试点研究强调了需要一份经过验证的患者问卷、更长的随访时间、手术干预的对照组以及围手术期药物的使用。任何旨在评估鼻内手术对鼻窦症状影响的临床试验都需要招募数百名患者,才能得出统计上有效的结论。
{"title":"Dacryocystorhinostomy for the treatment of nasolacrimal duct obstruction: a pilot trial to assess impact on coexisting sinus symptoms","authors":"Ankur N. Mehta, Wan-Ling Yi, A. Ananda, Raf Ghabriel","doi":"10.35119/ASJOO.V17I1.440","DOIUrl":"https://doi.org/10.35119/ASJOO.V17I1.440","url":null,"abstract":"Purpose: To report on coexistent sinus symptoms in a population of patients who underwent endonasal dacryocystorhinostomy (DCR) surgery for nasolacrimal duct obstruction (NLDO) in a pilot study designed to test and refine methods and to estimate patient sample size for a larger multicentre randomised trial. \u0000Methods: Ninety-four consecutive patients with NLDO who underwent endonasal DCR by three surgeons in both public and private practice over a two-year period were included in this study. Questionnaires were given preceding DCR surgery and at 10 weeks post-surgery. Sinus symptoms including sinusitis, nasal congestion, hyposmia, nasal discharge, and facial pressure were assessed in the questionnaire. All subjects underwent primary endonasal DCR and all patients underwent the same post-operative regimen. \u0000Results: Questionnaire responses revealed that 48/94 (51%) patients had one or more sinus symptoms prior to DCR surgery. Ten-week post-DCR follow-up questionnaires were obtained from 77/94 (82%) patients. About 20/31 (65%) patients with one or more sinus symptoms prior to DCR surgery reported resolution of coexisting sinus symptoms by 10 weeks post-DCR surgery. \u0000Conclusion: The data from this pilot study suggest that approximately half of patients attending for NLDO have coexisting sinus symptoms. There was some loss to follow-up. This pilot study highlighted the need for a validated patient questionnaire, longer length of follow-up, control groups for surgical intervention, and use of perioperative medications. Any clinical trial designed to assess the impact of endonasal surgery on sinus symptoms would need to enrol several hundred patients in order to reach a statistically valid conclusion.","PeriodicalId":39864,"journal":{"name":"Asian Journal of Ophthalmology","volume":"17 1","pages":"10-18"},"PeriodicalIF":0.0,"publicationDate":"2020-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46323959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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Asian Journal of Ophthalmology
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