Pub Date : 2012-10-18DOI: 10.1109/ENBENG.2012.6331393
S. T. Morais, P. Flores, J. Claro
Low back pain affects approximately 80% of the population at some point of their life, and lumbar degenerative disc disease is often indicated as the cause of that symptom. The mail goal of this work is to develop a biomechanical lumbar spine model, using multibody systems methodologies, useful for dynamic analysis, such as in the biomechanical behavior of pathologic and non-pathologic situations. Three subroutines were created to describe the work of ligaments, intervertebral discs and potential contact areas, using the multibody dynamics code MUBODYNA. The subroutines were tested using simple tests scenarios.
{"title":"Development of a biomechanical spine model for dynamic analysis","authors":"S. T. Morais, P. Flores, J. Claro","doi":"10.1109/ENBENG.2012.6331393","DOIUrl":"https://doi.org/10.1109/ENBENG.2012.6331393","url":null,"abstract":"Low back pain affects approximately 80% of the population at some point of their life, and lumbar degenerative disc disease is often indicated as the cause of that symptom. The mail goal of this work is to develop a biomechanical lumbar spine model, using multibody systems methodologies, useful for dynamic analysis, such as in the biomechanical behavior of pathologic and non-pathologic situations. Three subroutines were created to describe the work of ligaments, intervertebral discs and potential contact areas, using the multibody dynamics code MUBODYNA. The subroutines were tested using simple tests scenarios.","PeriodicalId":399131,"journal":{"name":"2012 IEEE 2nd Portuguese Meeting in Bioengineering (ENBENG)","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2012-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133584972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2012-10-18DOI: 10.1109/ENBENG.2012.6331349
S. Franco, C. Oliveira, H. T. Correia, S. Nascimento, J. M. B. de Ameida
It has been well known that wavefront aberrations of the eye are dynamic, changing continuously over time due to factors like accommodation, blinking, pupil size, tear film stability, etc. The goal of this work is to describe the developed methodologies for computing these dynamic aberrations. In this study, we present some preliminary results of real time measurement of monochromatic ocular aberrations during accommodative changes measured experimentally using a wavefront sensor.
{"title":"Real-time dynamic monochromatic ocular wavefront aberrations during accommodation: Preliminary results","authors":"S. Franco, C. Oliveira, H. T. Correia, S. Nascimento, J. M. B. de Ameida","doi":"10.1109/ENBENG.2012.6331349","DOIUrl":"https://doi.org/10.1109/ENBENG.2012.6331349","url":null,"abstract":"It has been well known that wavefront aberrations of the eye are dynamic, changing continuously over time due to factors like accommodation, blinking, pupil size, tear film stability, etc. The goal of this work is to describe the developed methodologies for computing these dynamic aberrations. In this study, we present some preliminary results of real time measurement of monochromatic ocular aberrations during accommodative changes measured experimentally using a wavefront sensor.","PeriodicalId":399131,"journal":{"name":"2012 IEEE 2nd Portuguese Meeting in Bioengineering (ENBENG)","volume":"49 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2012-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114468086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2012-10-18DOI: 10.1109/ENBENG.2012.6331339
V. Almeida, J. Borba, T. Pereira, H. Pereira, J. Cardoso, C. Correia
This paper envisages showing the potential of innovative non-invasive techniques based on affordable and easily operated instrumentation as well as user-friendly computer aided algorithms in the screening of cardiovascular (CV) diseases. These techniques are based on the assumption that arterial stiffness is currently an important predicator of the CV diseases development and can be assessed by analyzing the arterial pressure waveform (APW). A previously developed PZ based device for non-invasive APW capture is currently under test in clinical environment, using a heterogeneous population constituted by healthy and unhealthy subjects. A dedicated Matlab analysis tool was designed and developed to extract relevant information and further APW analysis. Several recordings of the APW in the same day and in consecutive months are being performed by trained observers, to evaluate its reproducibility. Data mining analysis is subsequently the last task where the Weka 3-6-5 package software is used. The usefulness of developing data mining algorithms for cardiovascular applications can benefit the CV screenings contributing for the early identification of arterial stiffness related patterns.
{"title":"Validation of a waveform delineator device for cardiac studies: Repeatability and data mining analysis","authors":"V. Almeida, J. Borba, T. Pereira, H. Pereira, J. Cardoso, C. Correia","doi":"10.1109/ENBENG.2012.6331339","DOIUrl":"https://doi.org/10.1109/ENBENG.2012.6331339","url":null,"abstract":"This paper envisages showing the potential of innovative non-invasive techniques based on affordable and easily operated instrumentation as well as user-friendly computer aided algorithms in the screening of cardiovascular (CV) diseases. These techniques are based on the assumption that arterial stiffness is currently an important predicator of the CV diseases development and can be assessed by analyzing the arterial pressure waveform (APW). A previously developed PZ based device for non-invasive APW capture is currently under test in clinical environment, using a heterogeneous population constituted by healthy and unhealthy subjects. A dedicated Matlab analysis tool was designed and developed to extract relevant information and further APW analysis. Several recordings of the APW in the same day and in consecutive months are being performed by trained observers, to evaluate its reproducibility. Data mining analysis is subsequently the last task where the Weka 3-6-5 package software is used. The usefulness of developing data mining algorithms for cardiovascular applications can benefit the CV screenings contributing for the early identification of arterial stiffness related patterns.","PeriodicalId":399131,"journal":{"name":"2012 IEEE 2nd Portuguese Meeting in Bioengineering (ENBENG)","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2012-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115768731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2012-10-18DOI: 10.1109/ENBENG.2012.6331348
L. M. Ramos-Ponce, J. Contreras-Esquivel, J. Saenz, G. Lara-Cisneros, Y. Garza-García
Mycophenolic acid (MPA) can be produced from Penicillium pinophilum by submerged fermentation. Here we reported the use of the Plackett-Burman design to screen the limiting components for MPA production and subsequent use the response surface methodology was employed to derive a statistical model for media optimization towards production of MPA. The results obtained of Plackett-Burman indicated limitations of three components in the basal medium, aspartic acid, methionine and Tween 80. The determinant coefficient was 0.80, ensuring a satisfactory adjustment of the model to the experimental values. This statistical design was good in improving the titer of MPA up 923 mg/L and a specific productivity of 0.05 mg AMP/mg of biomass/h after 10 day of fermentation.
{"title":"Study on production of mycophenolic acid by Penicillium pinophilum using response surface metodology","authors":"L. M. Ramos-Ponce, J. Contreras-Esquivel, J. Saenz, G. Lara-Cisneros, Y. Garza-García","doi":"10.1109/ENBENG.2012.6331348","DOIUrl":"https://doi.org/10.1109/ENBENG.2012.6331348","url":null,"abstract":"Mycophenolic acid (MPA) can be produced from Penicillium pinophilum by submerged fermentation. Here we reported the use of the Plackett-Burman design to screen the limiting components for MPA production and subsequent use the response surface methodology was employed to derive a statistical model for media optimization towards production of MPA. The results obtained of Plackett-Burman indicated limitations of three components in the basal medium, aspartic acid, methionine and Tween 80. The determinant coefficient was 0.80, ensuring a satisfactory adjustment of the model to the experimental values. This statistical design was good in improving the titer of MPA up 923 mg/L and a specific productivity of 0.05 mg AMP/mg of biomass/h after 10 day of fermentation.","PeriodicalId":399131,"journal":{"name":"2012 IEEE 2nd Portuguese Meeting in Bioengineering (ENBENG)","volume":"155 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2012-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123048672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2012-10-18DOI: 10.1109/ENBENG.2012.6331338
A. M. Raimundo, D. Quintela, A. Gaspar, A. M. A. Oliveira
The purpose of this work is the development and the validation of an accurate computer program for modeling of the thermal, the respiratory and the cardiovascular responses of a live or dead person exposed to any kind of environment while wearing different kinds of clothing and at rest or doing a moderate or intensive activity. The range of possible utilization is extensive, e.g., the optimization of sportive performance, the quantification of the thermal comfort achieved on exposition to moderate thermal environments, the evaluation of thermal stress and the risk of collapse in the execution of tasks in very hot or very cold situations or requiring high levels of effort and as support for medical activities. This manuscript describes the research efforts performed at the Mechanical Engineering Department of the Faculty of Sciences and Technology of University of Coimbra (DEM-FCTUC) in order to achieve mathematical and computational models suitable for the prediction of human body thermophysiological behavior.
{"title":"Development and validation of a computer program for simulation of the human body thermophysiological response","authors":"A. M. Raimundo, D. Quintela, A. Gaspar, A. M. A. Oliveira","doi":"10.1109/ENBENG.2012.6331338","DOIUrl":"https://doi.org/10.1109/ENBENG.2012.6331338","url":null,"abstract":"The purpose of this work is the development and the validation of an accurate computer program for modeling of the thermal, the respiratory and the cardiovascular responses of a live or dead person exposed to any kind of environment while wearing different kinds of clothing and at rest or doing a moderate or intensive activity. The range of possible utilization is extensive, e.g., the optimization of sportive performance, the quantification of the thermal comfort achieved on exposition to moderate thermal environments, the evaluation of thermal stress and the risk of collapse in the execution of tasks in very hot or very cold situations or requiring high levels of effort and as support for medical activities. This manuscript describes the research efforts performed at the Mechanical Engineering Department of the Faculty of Sciences and Technology of University of Coimbra (DEM-FCTUC) in order to achieve mathematical and computational models suitable for the prediction of human body thermophysiological behavior.","PeriodicalId":399131,"journal":{"name":"2012 IEEE 2nd Portuguese Meeting in Bioengineering (ENBENG)","volume":"49 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2012-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124740710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2012-10-18DOI: 10.1109/ENBENG.2012.6331377
Elisabeth Borges, A. P. Matos, J. Cardoso, C. Correia, T. Vasconcelos, N. Gomes
Electrical Impedance Spectroscopy, EIS, is widely used in the study of electrical properties and structure of biological tissues, namely in quality control of fruits and the characterization of specific botanical tissues. The present work aims to extend the EIS concept to identify structure damaging pathologies for in vivo vegetal tissue. This allows for the early detection of specific plant diseases with economic and environmental impact. Moreover, the commercially available EIS solutions miss a true frequency bandwidth analysis and, despite the general good performance, are unspecified for bioimpedance measurements and are often quite expensive. Consequently, these limitations are the main reason for erroneous interpretations and inaccurate results. Therefore, this work proposes the development of a dedicated bioEIS system, characterized by an appropriated frequency range (1kHz to 1MHz), suitable for biological applications, in such a way that it becomes possible to compensate the influence of potential errors in off-line analysis.
{"title":"Early detection and monitoring of plant diseases by Bioelectric Impedance Spectroscopy","authors":"Elisabeth Borges, A. P. Matos, J. Cardoso, C. Correia, T. Vasconcelos, N. Gomes","doi":"10.1109/ENBENG.2012.6331377","DOIUrl":"https://doi.org/10.1109/ENBENG.2012.6331377","url":null,"abstract":"Electrical Impedance Spectroscopy, EIS, is widely used in the study of electrical properties and structure of biological tissues, namely in quality control of fruits and the characterization of specific botanical tissues. The present work aims to extend the EIS concept to identify structure damaging pathologies for in vivo vegetal tissue. This allows for the early detection of specific plant diseases with economic and environmental impact. Moreover, the commercially available EIS solutions miss a true frequency bandwidth analysis and, despite the general good performance, are unspecified for bioimpedance measurements and are often quite expensive. Consequently, these limitations are the main reason for erroneous interpretations and inaccurate results. Therefore, this work proposes the development of a dedicated bioEIS system, characterized by an appropriated frequency range (1kHz to 1MHz), suitable for biological applications, in such a way that it becomes possible to compensate the influence of potential errors in off-line analysis.","PeriodicalId":399131,"journal":{"name":"2012 IEEE 2nd Portuguese Meeting in Bioengineering (ENBENG)","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2012-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114519501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2012-10-18DOI: 10.1109/ENBENG.2012.6331344
C. Santos, R. Lavrador, G. Caetano, N. Lori, R. Travasso
The purpose of this work is to develop improvements on the most modern forms of white matter fiber tracking in the human brain. This development requires the use of computer simulations to assess the limits of the fiber tracking technology, and then the results of that simulation are used to make a thorough assessment of the experimental results in living human brains. The used fiber tracking techniques are q-ball imaging and diffusion spectrum imaging.
{"title":"Use of Shannon information to relate function and structure in the brain using diffusion spectrum imaging MRI","authors":"C. Santos, R. Lavrador, G. Caetano, N. Lori, R. Travasso","doi":"10.1109/ENBENG.2012.6331344","DOIUrl":"https://doi.org/10.1109/ENBENG.2012.6331344","url":null,"abstract":"The purpose of this work is to develop improvements on the most modern forms of white matter fiber tracking in the human brain. This development requires the use of computer simulations to assess the limits of the fiber tracking technology, and then the results of that simulation are used to make a thorough assessment of the experimental results in living human brains. The used fiber tracking techniques are q-ball imaging and diffusion spectrum imaging.","PeriodicalId":399131,"journal":{"name":"2012 IEEE 2nd Portuguese Meeting in Bioengineering (ENBENG)","volume":"56 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2012-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114786415","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2012-10-18DOI: 10.1109/ENBENG.2012.6331386
T. M. Lopes, C. Correia
Local pulse-wave velocity (PWV) is recognized as the simplest and most reproducible process of non-invasively assessing the vascular marker of arterial stiffness that allowing the risk of cardiovascular diseases to be determinate. Devices currently available for local PWV measurement have not yet been generalized to clinical practice since they require high technical expertise and most of them are limited in precision, due to the lack of reliable signal processing methods. This work describes a new type of probes, based on a piezoelectric sensor in different configurations, single probe and double probe. The principle of PWV measurement involves determination of the pulse transit time between the signals acquired simultaneously by both piezoelectric placed 23 mm apart in the same probe. The double probe characterization is accomplished in different studies, carried out in a dedicated test bench system, capable of reproducing a range of clinically relevant properties of the cardiovascular system.
{"title":"Double probe based in piezoelectric sensors for local pulse wave velocity assessment","authors":"T. M. Lopes, C. Correia","doi":"10.1109/ENBENG.2012.6331386","DOIUrl":"https://doi.org/10.1109/ENBENG.2012.6331386","url":null,"abstract":"Local pulse-wave velocity (PWV) is recognized as the simplest and most reproducible process of non-invasively assessing the vascular marker of arterial stiffness that allowing the risk of cardiovascular diseases to be determinate. Devices currently available for local PWV measurement have not yet been generalized to clinical practice since they require high technical expertise and most of them are limited in precision, due to the lack of reliable signal processing methods. This work describes a new type of probes, based on a piezoelectric sensor in different configurations, single probe and double probe. The principle of PWV measurement involves determination of the pulse transit time between the signals acquired simultaneously by both piezoelectric placed 23 mm apart in the same probe. The double probe characterization is accomplished in different studies, carried out in a dedicated test bench system, capable of reproducing a range of clinically relevant properties of the cardiovascular system.","PeriodicalId":399131,"journal":{"name":"2012 IEEE 2nd Portuguese Meeting in Bioengineering (ENBENG)","volume":"37 3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2012-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126745610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2012-10-18DOI: 10.1109/ENBENG.2012.6331383
T. Pereira, P. Barbeiro, J. Lemos, M. Morgado, E. Silva
The aim of this work is to provide a Panoptic™ ophthalmoscope with digital data acquisition. In fact, most ophthalmoscopes used in daily clinical practice do not contain the data recording ability. Therefore, the main advantages of a digital ophthalmoscope are, among others, better quality data sharing, the possibility of exam's reassessment and improved medical teaching. Once the challenge was presented by clinical staff working at Coimbra University Hospital, several prototype's technical drawings were idealized in AutoCAD® 2011 environment at Blueworks, and a number of experiments in optics laboratory at Institute of Biomedical Research in Light and Image (IBILI) were accomplished as well. In the end, the prototype developed contains a camera inside and it fits into the ophthalmoscope. In order to verify its capacity to record retinal images and to detect ocular fundus pathologies, the prototype has been clinically tested and its impact in medical community has been markedly positive.
{"title":"Digital image acquisition for ophthalmoscope","authors":"T. Pereira, P. Barbeiro, J. Lemos, M. Morgado, E. Silva","doi":"10.1109/ENBENG.2012.6331383","DOIUrl":"https://doi.org/10.1109/ENBENG.2012.6331383","url":null,"abstract":"The aim of this work is to provide a Panoptic™ ophthalmoscope with digital data acquisition. In fact, most ophthalmoscopes used in daily clinical practice do not contain the data recording ability. Therefore, the main advantages of a digital ophthalmoscope are, among others, better quality data sharing, the possibility of exam's reassessment and improved medical teaching. Once the challenge was presented by clinical staff working at Coimbra University Hospital, several prototype's technical drawings were idealized in AutoCAD® 2011 environment at Blueworks, and a number of experiments in optics laboratory at Institute of Biomedical Research in Light and Image (IBILI) were accomplished as well. In the end, the prototype developed contains a camera inside and it fits into the ophthalmoscope. In order to verify its capacity to record retinal images and to detect ocular fundus pathologies, the prototype has been clinically tested and its impact in medical community has been markedly positive.","PeriodicalId":399131,"journal":{"name":"2012 IEEE 2nd Portuguese Meeting in Bioengineering (ENBENG)","volume":"38 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2012-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123439658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2012-10-18DOI: 10.1109/ENBENG.2012.6331395
P. Guimarães, P. Serranho, M. Castelo‐Branco, Rui Bernardes
Prior studies have suggested a connection between the deprivation of visual stimuli and the degeneration of cortical visual areas. Retinal and cortical thickness allows inferring on the integrity of the retina and the cortex, respectively. We intend to develop a novel methodology to allow establishing the correlation between retinal and cortical thickness, automatically and in vivo. Cortical thickness requires proper visual stimuli to establish to which location within the ocular fundus a given visual cortex location refers to. Through retinotopic mapping the link between the visual space and the visual cortex can be established, although with low resolution. Automated software that maps the visual area and interpolates retinotopic data was developed.
{"title":"Segmentation processes and pattern recognition in retina and brain imaging","authors":"P. Guimarães, P. Serranho, M. Castelo‐Branco, Rui Bernardes","doi":"10.1109/ENBENG.2012.6331395","DOIUrl":"https://doi.org/10.1109/ENBENG.2012.6331395","url":null,"abstract":"Prior studies have suggested a connection between the deprivation of visual stimuli and the degeneration of cortical visual areas. Retinal and cortical thickness allows inferring on the integrity of the retina and the cortex, respectively. We intend to develop a novel methodology to allow establishing the correlation between retinal and cortical thickness, automatically and in vivo. Cortical thickness requires proper visual stimuli to establish to which location within the ocular fundus a given visual cortex location refers to. Through retinotopic mapping the link between the visual space and the visual cortex can be established, although with low resolution. Automated software that maps the visual area and interpolates retinotopic data was developed.","PeriodicalId":399131,"journal":{"name":"2012 IEEE 2nd Portuguese Meeting in Bioengineering (ENBENG)","volume":"19 9","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2012-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"120941686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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