A significant issue in public health is patient safety. Patient safety is a health issue affecting people worldwide, both in developed countries and in developing countries. It is crucial to have a variety of nursing practices, including management, education, and clinics, taking into account the significance of patient safety in terms of the effectiveness of care and patient outcomes. The review found that more work needs to be done to improve patient safety. This includes lowering the number of mistakes, falls, hospital infections, and surgical complications and improving other safety features so that all hospitals can be safer.
{"title":"Review of patient safety in nursing","authors":"Shikha Gupta, Veena S Chaudhary, Raj Kumar Sharma, Asha Yadav, Rashmi, Rashmi Panday","doi":"10.53771/ijbpsa.2023.5.2.0045","DOIUrl":"https://doi.org/10.53771/ijbpsa.2023.5.2.0045","url":null,"abstract":"A significant issue in public health is patient safety. Patient safety is a health issue affecting people worldwide, both in developed countries and in developing countries. It is crucial to have a variety of nursing practices, including management, education, and clinics, taking into account the significance of patient safety in terms of the effectiveness of care and patient outcomes. The review found that more work needs to be done to improve patient safety. This includes lowering the number of mistakes, falls, hospital infections, and surgical complications and improving other safety features so that all hospitals can be safer.","PeriodicalId":400966,"journal":{"name":"International Journal of Biological and Pharmaceutical Sciences Archive","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115165040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-06-30DOI: 10.53771/ijbpsa.2023.5.2.0053
Desdiani Desdiani
Emphysema bullae are often found in patients with chronic obstructive pulmonary disease and if the size of the bulla fulfills > 30% of the hemithorax, it can be called a giant bullae. A giant bullae can be similar to a pneumothorax, requiring a CT scan of the chest to avoid misdiagnosis and unnecessary procedures. The difference between a bulla and a pneumothorax obtained from imaging results is that if the lung collapses towards the ipsilateral hilum it is called a pneumothorax, while the bulla will appear to surround or wrap around the lung. Asthma is a disease characterized by chronic inflammation and bronchoconstriction. In acute asthma attacks or exacerbations, bronchoconstriction causes severe bilateral lung parenchymal inflation.We present a case of a 32-years-old male with multiple bullae, a complete history of tuberculosis treatment and suffering from asthma since childhood but not controlled. In this case, the likelihood of Multiple bullae in asthmatic patients, needs to be a concern, as well as the importance of evaluation and strict follow-up to reduce shortness of breath and improve the patient's quality of life.
{"title":"Multiple bullae in asthmatic patients","authors":"Desdiani Desdiani","doi":"10.53771/ijbpsa.2023.5.2.0053","DOIUrl":"https://doi.org/10.53771/ijbpsa.2023.5.2.0053","url":null,"abstract":"Emphysema bullae are often found in patients with chronic obstructive pulmonary disease and if the size of the bulla fulfills > 30% of the hemithorax, it can be called a giant bullae. A giant bullae can be similar to a pneumothorax, requiring a CT scan of the chest to avoid misdiagnosis and unnecessary procedures. The difference between a bulla and a pneumothorax obtained from imaging results is that if the lung collapses towards the ipsilateral hilum it is called a pneumothorax, while the bulla will appear to surround or wrap around the lung. Asthma is a disease characterized by chronic inflammation and bronchoconstriction. In acute asthma attacks or exacerbations, bronchoconstriction causes severe bilateral lung parenchymal inflation.We present a case of a 32-years-old male with multiple bullae, a complete history of tuberculosis treatment and suffering from asthma since childhood but not controlled. In this case, the likelihood of Multiple bullae in asthmatic patients, needs to be a concern, as well as the importance of evaluation and strict follow-up to reduce shortness of breath and improve the patient's quality of life.","PeriodicalId":400966,"journal":{"name":"International Journal of Biological and Pharmaceutical Sciences Archive","volume":"84 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126270308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-06-30DOI: 10.53771/ijbpsa.2023.5.2.0051
Amit Kapila, Chinky Goyal, Amrit Malik, S.P. Abhiram, Jadhav Viraj Vilas
Hingula, very well known as Cinnabar, is a chief ore of Mercury. It is available as natural ore and is also prepared artificially. While there are other ores of mercury, Hingula is considered to be the best ore, and Hingulottha Paarada is said to be equal to properties of Ashta Samskarita Paarada. An effort is made hereby to compile all the information related Hingula including its Historical aspect, origin, synonyms, classification according to different texts, artificial preparation of Hingula, Grahya Lakshana, complications caused due to Ashuddh Hingula sevan and its Chikitsa, Shodhan and Marana of Hingula, Extraction of parade from Hingula and its superiority over other types of Parada, Rasa Panchaka and Upyoga of Hingula. This paper also covers the Bio-medical counterpart of Hingula i.e. Cinnabar including its varieties, mineralogical characters and chemical properties.
{"title":"An explicit appraisal on HINGULA: An indigenous component of Rasaushadhies","authors":"Amit Kapila, Chinky Goyal, Amrit Malik, S.P. Abhiram, Jadhav Viraj Vilas","doi":"10.53771/ijbpsa.2023.5.2.0051","DOIUrl":"https://doi.org/10.53771/ijbpsa.2023.5.2.0051","url":null,"abstract":"Hingula, very well known as Cinnabar, is a chief ore of Mercury. It is available as natural ore and is also prepared artificially. While there are other ores of mercury, Hingula is considered to be the best ore, and Hingulottha Paarada is said to be equal to properties of Ashta Samskarita Paarada. An effort is made hereby to compile all the information related Hingula including its Historical aspect, origin, synonyms, classification according to different texts, artificial preparation of Hingula, Grahya Lakshana, complications caused due to Ashuddh Hingula sevan and its Chikitsa, Shodhan and Marana of Hingula, Extraction of parade from Hingula and its superiority over other types of Parada, Rasa Panchaka and Upyoga of Hingula. This paper also covers the Bio-medical counterpart of Hingula i.e. Cinnabar including its varieties, mineralogical characters and chemical properties.","PeriodicalId":400966,"journal":{"name":"International Journal of Biological and Pharmaceutical Sciences Archive","volume":"28 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131390605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-06-30DOI: 10.53771/ijbpsa.2023.5.2.0054
W. Islam, Jahan Jahida Begum, Ara Khanam
The adult population of Cryptolestes pusillus (Schon.) was significantly (P<0.001) reduced after 3-, 6- and 9-months storage periods at different concentrations of Spinosad than those of control medium. Spinosad at all concentrations reduced mean number of larval 5.33±0.72 to 52.00±0.94, 5.67±1.36 to 32.00±1.41 and 2.67±0.54 to 54.33±0.72 after 3, pupal 3.33±1.09 to 26.00±0.94, 3.33±0.72 to 26.00±1.25 and 2.33±0.29 to 16.33±0.27 after 6 and adult 5.33±1.19 to 62.00±0.47, 2.33±0.27 to 72.00±1.25 and 2.33±1.09 to 58.00±1.25 after 9 months storage period. The percent of repulsion (PRC) were always higher in higher concentrations but lower in lower concentrations in every cases. The total population of C. pusillus was 152.00±1.15 and 790.33±2.60 after 1st and 2.67±1.09 and 20.67±3.34 after 2nd generations. Spinosad effectively reduced the survivability and population of C. pusillus of the treated wheat.
{"title":"Contact and gustatory effects of Spinosad on inhibition of population build-up of Cryptolestes pusillus (Schon.) (Coleoptera: Cucujidae) after different storage periods in whea","authors":"W. Islam, Jahan Jahida Begum, Ara Khanam","doi":"10.53771/ijbpsa.2023.5.2.0054","DOIUrl":"https://doi.org/10.53771/ijbpsa.2023.5.2.0054","url":null,"abstract":"The adult population of Cryptolestes pusillus (Schon.) was significantly (P<0.001) reduced after 3-, 6- and 9-months storage periods at different concentrations of Spinosad than those of control medium. Spinosad at all concentrations reduced mean number of larval 5.33±0.72 to 52.00±0.94, 5.67±1.36 to 32.00±1.41 and 2.67±0.54 to 54.33±0.72 after 3, pupal 3.33±1.09 to 26.00±0.94, 3.33±0.72 to 26.00±1.25 and 2.33±0.29 to 16.33±0.27 after 6 and adult 5.33±1.19 to 62.00±0.47, 2.33±0.27 to 72.00±1.25 and 2.33±1.09 to 58.00±1.25 after 9 months storage period. The percent of repulsion (PRC) were always higher in higher concentrations but lower in lower concentrations in every cases. The total population of C. pusillus was 152.00±1.15 and 790.33±2.60 after 1st and 2.67±1.09 and 20.67±3.34 after 2nd generations. Spinosad effectively reduced the survivability and population of C. pusillus of the treated wheat.","PeriodicalId":400966,"journal":{"name":"International Journal of Biological and Pharmaceutical Sciences Archive","volume":"143 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115804822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-06-30DOI: 10.53771/ijbpsa.2023.5.2.0049
B. A. Harsojuwono, I. Satriawan, S. Mulyani
Turmeric and tamarind leaves extract creams have potential as anti-aging agents, but their use has never been studied in vivo. Therefore the purpose of this study was to determine the effectiveness of turmeric and tamarind leaves extract cream in maintaining skin quality in vivo. This research was carried out by applying turmeric and tamarind leaf extract cream to 24 volunteers (having received approval from the ethical commission). Variables observed included sebum content, pore size, pigment content, moisture or moisture content, elasticity and collagenase content. The results showed that turmeric and tamarind leaves extract cream can increase sebum content up to 31.1%, reduce pore size to 0.017 mm, increase pigment content up to 13.2%, moisture up to 54.2%, elasticity up to 21.4% and collagenase content up to 37.3%.
{"title":"Assessing the effectiveness of turmeric and tamarind leaves extract cream as anti-aging in vivo","authors":"B. A. Harsojuwono, I. Satriawan, S. Mulyani","doi":"10.53771/ijbpsa.2023.5.2.0049","DOIUrl":"https://doi.org/10.53771/ijbpsa.2023.5.2.0049","url":null,"abstract":"Turmeric and tamarind leaves extract creams have potential as anti-aging agents, but their use has never been studied in vivo. Therefore the purpose of this study was to determine the effectiveness of turmeric and tamarind leaves extract cream in maintaining skin quality in vivo. This research was carried out by applying turmeric and tamarind leaf extract cream to 24 volunteers (having received approval from the ethical commission). Variables observed included sebum content, pore size, pigment content, moisture or moisture content, elasticity and collagenase content. The results showed that turmeric and tamarind leaves extract cream can increase sebum content up to 31.1%, reduce pore size to 0.017 mm, increase pigment content up to 13.2%, moisture up to 54.2%, elasticity up to 21.4% and collagenase content up to 37.3%.","PeriodicalId":400966,"journal":{"name":"International Journal of Biological and Pharmaceutical Sciences Archive","volume":"PP 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126418955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-06-30DOI: 10.53771/ijbpsa.2023.5.2.0050
C. Marchiori
Rearing records suggest that most temperate species can be found in a number of different deciduous trees, but some Clusiidae have also been found in conifers, and larvae of Sobarocephala have been found in termite colonies, as well as decaying wood, found the larvae evidently associated with the burrows of coleopterous insects and to be relatively sluggish and slow moving. Clusiidae larvae are probably at least facultatively predaceous on larvae of other wood-boring insects. The objective of the manuscript was to describe the territorial behavior of the males and also the biological Clusiidae. This work consists of bibliographical research of scientific articles published in national and international academic scientific journals classified by the Coordination for the Improvement of Higher Education Personnel (CAPES). Document analysis was used as a data collection method to gather information on theoretical books, theses banks, university dissertations, documents and digital platforms websites such as HAL, SSRN and ResearchGate.
{"title":"Description of the Clausiidae family","authors":"C. Marchiori","doi":"10.53771/ijbpsa.2023.5.2.0050","DOIUrl":"https://doi.org/10.53771/ijbpsa.2023.5.2.0050","url":null,"abstract":"Rearing records suggest that most temperate species can be found in a number of different deciduous trees, but some Clusiidae have also been found in conifers, and larvae of Sobarocephala have been found in termite colonies, as well as decaying wood, found the larvae evidently associated with the burrows of coleopterous insects and to be relatively sluggish and slow moving. Clusiidae larvae are probably at least facultatively predaceous on larvae of other wood-boring insects. The objective of the manuscript was to describe the territorial behavior of the males and also the biological Clusiidae. This work consists of bibliographical research of scientific articles published in national and international academic scientific journals classified by the Coordination for the Improvement of Higher Education Personnel (CAPES). Document analysis was used as a data collection method to gather information on theoretical books, theses banks, university dissertations, documents and digital platforms websites such as HAL, SSRN and ResearchGate.","PeriodicalId":400966,"journal":{"name":"International Journal of Biological and Pharmaceutical Sciences Archive","volume":"24 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131952556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-06-30DOI: 10.53771/ijbpsa.2023.5.2.0048
Fimia Duarte R, Osés Rodríguez R, González Ronda Y, del Valle Laveaga D, Diéguez Fernández L, Wilford González FM, Robert Vogt P, González Rodríguez IC
Dengue continues to be the main arbovirosis, with endemic characteristics, in at least 100 countries, affecting an average of 50 million patients per year, and with a high incidence in pediatric ages. To mathematically model the cases of Dengue in pediatric age through the methodology of the Objective Regression Regressive, during the period 2016-2021 in the province of Villa Clara, Cuba. A descriptive, retrospective, analytical-statistical (Objective Regression Regressive methodology) and prospective longitudinal study was carried out. The study area corresponded to Villa Clara province, which is located in the center of Cuba, where the population under study was the 13 municipalities that make up the province. The total number of cases of Dengue fever during the six years covered by the study was 2 013. A database was created for confirmed cases of Dengue in Villa Clara during the years 2016 to 2021, specifically for children under 18 years of age, where the data were entered in files and processed using the SPSS version 22 statistical package, which made it possible to carry out a mathematical modeling of Dengue cases, in the short and long term. The plotting of confirmed cases of Dengue fever showed that the highest incidence of cases was in the months from July to November, with an average of 28 cases studied. The short-term model depends on the cases returned in 1, 2, 7 and 14 months, which indicates a strong dependence on the previous month, so that all monitoring, surveillance, management, control and sanitation actions carried out in advance will have a positive impact on the following month, while the long-term model depended on the cases returned in 12 months, and the trend turned out to be positive and significant. It was possible to model the cases of Dengue, where the trend was to a non-significant decrease in the short term, while in the long term, this trend was to a significant increase, and for which, the cases depended on 1, 2, 7 and 14 months ago, so the best model was the long term, being able to predict the behavior of this infectious entity one year in advance, as well as the extension to longer dates in years.
{"title":"Modeling of Dengue cases in pediatric age using the objective regression regressive methodology in Villa Clara, Cuba","authors":"Fimia Duarte R, Osés Rodríguez R, González Ronda Y, del Valle Laveaga D, Diéguez Fernández L, Wilford González FM, Robert Vogt P, González Rodríguez IC","doi":"10.53771/ijbpsa.2023.5.2.0048","DOIUrl":"https://doi.org/10.53771/ijbpsa.2023.5.2.0048","url":null,"abstract":"Dengue continues to be the main arbovirosis, with endemic characteristics, in at least 100 countries, affecting an average of 50 million patients per year, and with a high incidence in pediatric ages. To mathematically model the cases of Dengue in pediatric age through the methodology of the Objective Regression Regressive, during the period 2016-2021 in the province of Villa Clara, Cuba. A descriptive, retrospective, analytical-statistical (Objective Regression Regressive methodology) and prospective longitudinal study was carried out. The study area corresponded to Villa Clara province, which is located in the center of Cuba, where the population under study was the 13 municipalities that make up the province. The total number of cases of Dengue fever during the six years covered by the study was 2 013. A database was created for confirmed cases of Dengue in Villa Clara during the years 2016 to 2021, specifically for children under 18 years of age, where the data were entered in files and processed using the SPSS version 22 statistical package, which made it possible to carry out a mathematical modeling of Dengue cases, in the short and long term. The plotting of confirmed cases of Dengue fever showed that the highest incidence of cases was in the months from July to November, with an average of 28 cases studied. The short-term model depends on the cases returned in 1, 2, 7 and 14 months, which indicates a strong dependence on the previous month, so that all monitoring, surveillance, management, control and sanitation actions carried out in advance will have a positive impact on the following month, while the long-term model depended on the cases returned in 12 months, and the trend turned out to be positive and significant. It was possible to model the cases of Dengue, where the trend was to a non-significant decrease in the short term, while in the long term, this trend was to a significant increase, and for which, the cases depended on 1, 2, 7 and 14 months ago, so the best model was the long term, being able to predict the behavior of this infectious entity one year in advance, as well as the extension to longer dates in years.","PeriodicalId":400966,"journal":{"name":"International Journal of Biological and Pharmaceutical Sciences Archive","volume":"316 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115869178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ochratoxin A (OTA) is a natural toxin and produced by various fungi of the genus Aspergillus and Penicillium and the second one in toxicity among mycotoxins. Recent studies have shown that grape seed extract (GSE) has a protective effect on mycotoxin-induced toxicity. The aim of this study was to investigate the protective effect GSE on OTA-induced genotoxicity, liver and kidney injury in rats. Forty mature Wistar albino male rats with similar body weight were divided into four groups (10 rats each): 1- untreated control group, 2- OTA treated group (1.7 mg/Kg bw, i. p.), 3- OTA + 75 mg/kg bw GSE treated group, 4- OTA + 150 mg/kg bw GSE treated group. Rats were treated for 15 days and at the end of experiments, blood, liver and kidney tissue homogenates, as well spermatocyte cells were harvested to determine the effect of OTA on geno-, hepato-, and renal toxicity in rats and the protective role of GSE. The results showed that GSE could significantly alleviate genotoxicity, DNA damage and improve the liver and kidney injury induced by OTA toxicity in male albino rats due to its antioxidant and anti-inflammatory activity.
赭曲霉毒素A (Ochratoxin A, OTA)是一种天然毒素，由曲霉属和青霉属的多种真菌产生，毒性位居真菌毒素第二位。近年来的研究表明，葡萄籽提取物(GSE)对真菌毒素诱导的毒性具有保护作用。本研究旨在探讨GSE对ota致大鼠遗传毒性及肝、肾损伤的保护作用。将40只体重相近的成年Wistar白化雄性大鼠分为4组(每组10只):1-未处理对照组、2- OTA处理组(1.7 mg/Kg bw, p.)、3- OTA + 75 mg/Kg bw GSE处理组、4- OTA + 150 mg/Kg bw GSE处理组。大鼠治疗15天，实验结束时采集血液、肝脏和肾脏组织匀浆以及精母细胞，以确定OTA对大鼠基因、肝脏和肾脏毒性的影响以及GSE的保护作用。结果表明，GSE具有明显的抗氧化和抗炎作用，可明显减轻OTA毒性对雄性白化大鼠的遗传毒性、DNA损伤和改善肝肾损伤。
{"title":"Protective role of grape seed extract on genotoxicity, hepatic, and renal dysfunction induced by ochratoxin A in rats","authors":"Shenouda Maroun Girgis, Mahrousa Mohamed Hassanane, Salwa Mohamed Kassem, Somaia Ahmed Nada","doi":"10.53771/ijbpsa.2023.5.2.0035","DOIUrl":"https://doi.org/10.53771/ijbpsa.2023.5.2.0035","url":null,"abstract":"Ochratoxin A (OTA) is a natural toxin and produced by various fungi of the genus Aspergillus and Penicillium and the second one in toxicity among mycotoxins. Recent studies have shown that grape seed extract (GSE) has a protective effect on mycotoxin-induced toxicity. The aim of this study was to investigate the protective effect GSE on OTA-induced genotoxicity, liver and kidney injury in rats. Forty mature Wistar albino male rats with similar body weight were divided into four groups (10 rats each): 1- untreated control group, 2- OTA treated group (1.7 mg/Kg bw, i. p.), 3- OTA + 75 mg/kg bw GSE treated group, 4- OTA + 150 mg/kg bw GSE treated group. Rats were treated for 15 days and at the end of experiments, blood, liver and kidney tissue homogenates, as well spermatocyte cells were harvested to determine the effect of OTA on geno-, hepato-, and renal toxicity in rats and the protective role of GSE. The results showed that GSE could significantly alleviate genotoxicity, DNA damage and improve the liver and kidney injury induced by OTA toxicity in male albino rats due to its antioxidant and anti-inflammatory activity.","PeriodicalId":400966,"journal":{"name":"International Journal of Biological and Pharmaceutical Sciences Archive","volume":"86 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124152982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-05-30DOI: 10.53771/ijbpsa.2023.5.2.0036
Ebiere Dode, Deghinmotei Alfred-Ugbenbo, Samuel J. Bunu, Akarhiunu Marcus
Background: Hypertension (HT) is one of the primary causes of death worldwide, accounting for 13% of all deaths. Most cardiovascular disease (CVD) outbreaks in Africa are driven by hypertension, although global detection, awareness, treatment, and control rates are low. Aim: the study aimed to analyze the physicochemical parameters and quality assessment of different brands of Lisinopril. Method: Five (5) brands of Lisinopril oral tablets (10mg) were purchased and coded LSP1, LSP2, LSP3, LSP4, and LSP5. Different test including weight uniformity, standardizations, extraction, titrimetric (aqueous and non-aqueous) analysis, and quality determination of all the brands was conducted using standard procedures outlined in the United States Pharmacopoeia (USP). Result: All brands of Lisinopril used in the analysis conformed to the weight uniformity test. LSP1 conformed to the standard purity range in aqueous titrimetric analysis (98.5%), while the other brands had a close percentage but did not fall within the stated standard with a percentage purity of 82.2% (LSP2), 75.5% (LSP3), 87.1% (LSP4), and 75.6% (LSP5), respectively. For the non-aqueous titration, LSP 1 and LSP 2, conform to the standard percentage purity outlined in the USP, with 100.65% (LSP1), and 97.55% (LSP2). The brands had a percentage purity of 72.78% (LSP3), 88.26% (LSP4), and 88.26% (LSP 5), respectively. Conclusion: the method used in this study can be easily employed in the quality assessment and physicochemical analysis of solid dosage formulations commonly utilized by patients because it is rapid, efficient, cost-effective, less technical and reproducible.
{"title":"Physicochemical analysis and quality assessment of Lisinopril oral formulations used in the management of hypertension","authors":"Ebiere Dode, Deghinmotei Alfred-Ugbenbo, Samuel J. Bunu, Akarhiunu Marcus","doi":"10.53771/ijbpsa.2023.5.2.0036","DOIUrl":"https://doi.org/10.53771/ijbpsa.2023.5.2.0036","url":null,"abstract":"Background: Hypertension (HT) is one of the primary causes of death worldwide, accounting for 13% of all deaths. Most cardiovascular disease (CVD) outbreaks in Africa are driven by hypertension, although global detection, awareness, treatment, and control rates are low. Aim: the study aimed to analyze the physicochemical parameters and quality assessment of different brands of Lisinopril. Method: Five (5) brands of Lisinopril oral tablets (10mg) were purchased and coded LSP1, LSP2, LSP3, LSP4, and LSP5. Different test including weight uniformity, standardizations, extraction, titrimetric (aqueous and non-aqueous) analysis, and quality determination of all the brands was conducted using standard procedures outlined in the United States Pharmacopoeia (USP). Result: All brands of Lisinopril used in the analysis conformed to the weight uniformity test. LSP1 conformed to the standard purity range in aqueous titrimetric analysis (98.5%), while the other brands had a close percentage but did not fall within the stated standard with a percentage purity of 82.2% (LSP2), 75.5% (LSP3), 87.1% (LSP4), and 75.6% (LSP5), respectively. For the non-aqueous titration, LSP 1 and LSP 2, conform to the standard percentage purity outlined in the USP, with 100.65% (LSP1), and 97.55% (LSP2). The brands had a percentage purity of 72.78% (LSP3), 88.26% (LSP4), and 88.26% (LSP 5), respectively. Conclusion: the method used in this study can be easily employed in the quality assessment and physicochemical analysis of solid dosage formulations commonly utilized by patients because it is rapid, efficient, cost-effective, less technical and reproducible.","PeriodicalId":400966,"journal":{"name":"International Journal of Biological and Pharmaceutical Sciences Archive","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127658570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nursing staff turnover and absenteeism are reduced thanks to job satisfaction, which also enhances performance and productivity. Further research is required to determine how the interaction of these factors is impacted by individual initiative. This study's goal was to look into the relationships between nurses' personal initiative, work environment, and job satisfaction. According to the findings, high levels of individual initiative and favorable opinions of the nursing workplace were major factors in explaining job satisfaction. The working environment needs to be improved, the initiative needs to be encouraged, and nurses need to be encouraged to be active, share their knowledge, and foster innovation.
{"title":"Review of workplace characteristics and Self-motivation as Indicators of nurses' Job satisfaction","authors":"Shikha Gupta, Liji Chaudhary, Garima Rohilla, Natasha Verma, V. Verma, Preeti Pal, Manju Rajput, Neha Katoch","doi":"10.53771/ijbpsa.2023.5.2.0041","DOIUrl":"https://doi.org/10.53771/ijbpsa.2023.5.2.0041","url":null,"abstract":"Nursing staff turnover and absenteeism are reduced thanks to job satisfaction, which also enhances performance and productivity. Further research is required to determine how the interaction of these factors is impacted by individual initiative. This study's goal was to look into the relationships between nurses' personal initiative, work environment, and job satisfaction. According to the findings, high levels of individual initiative and favorable opinions of the nursing workplace were major factors in explaining job satisfaction. The working environment needs to be improved, the initiative needs to be encouraged, and nurses need to be encouraged to be active, share their knowledge, and foster innovation.","PeriodicalId":400966,"journal":{"name":"International Journal of Biological and Pharmaceutical Sciences Archive","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121735986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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