Background Coronavirus disease 2019 (COVID-19) pandemic has resulted in remarkable changes in the profiles of diseases including dermatologic conditions. Aim To investigate the patterns of skin diseases in Egypt during the COVID-19 pandemic. Patients and methods In this cross-sectional study, we reviewed the data of patients who visited dermatology clinics between August 2020 and January 2021 and compared them with the data from the same clinics in the previous year. Results The total number of patients who attended the dermatology clinics between August 2020 and January 2021 was 803 as compared with 1611 patients in the corresponding period of the previous year (49.84% reduction). During the COVID-19 pandemic, there was a significant increase in the frequency of allergic contact dermatitis, irritant contact dermatitis, pityriasis rosea, alopecia areata, erythema multiforme, vasculitis, herpes zoster, and chicken pox (P<0.05). On the contrary, some dermatological conditions such as urticaria and nonscarring hair loss had significantly decreased frequencies during the COVID-19 pandemic (P<0.05). Several skin diseases had unchanged frequencies during the COVID-19 pandemic. These included skin infections (other than viral infections), bullous disorders, some eczematous skin diseases, papulosquamous disorders, and disorders of skin pigmentation. Conclusion This study indicates a significant reduction in the total number of patients attending dermatology clinics in Egypt during the COVID-19 pandemic. The frequency of some skin diseases increased significantly, whereas other skin diseases decreased significantly or remained unchanged during the pandemic. Periodic evaluation of the epidemiologic characteristics of skin diseases is required at different stages of evolution of the COVID-19 pandemic.
{"title":"Frequency of skin diseases in Egyptian population during coronavirus disease 2019 pandemic: a hospital-based cross-sectional study","authors":"M. Mohamed, N. Mohammed, R. Saleh","doi":"10.4103/ejdv.ejdv_38_21","DOIUrl":"https://doi.org/10.4103/ejdv.ejdv_38_21","url":null,"abstract":"Background Coronavirus disease 2019 (COVID-19) pandemic has resulted in remarkable changes in the profiles of diseases including dermatologic conditions. Aim To investigate the patterns of skin diseases in Egypt during the COVID-19 pandemic. Patients and methods In this cross-sectional study, we reviewed the data of patients who visited dermatology clinics between August 2020 and January 2021 and compared them with the data from the same clinics in the previous year. Results The total number of patients who attended the dermatology clinics between August 2020 and January 2021 was 803 as compared with 1611 patients in the corresponding period of the previous year (49.84% reduction). During the COVID-19 pandemic, there was a significant increase in the frequency of allergic contact dermatitis, irritant contact dermatitis, pityriasis rosea, alopecia areata, erythema multiforme, vasculitis, herpes zoster, and chicken pox (P<0.05). On the contrary, some dermatological conditions such as urticaria and nonscarring hair loss had significantly decreased frequencies during the COVID-19 pandemic (P<0.05). Several skin diseases had unchanged frequencies during the COVID-19 pandemic. These included skin infections (other than viral infections), bullous disorders, some eczematous skin diseases, papulosquamous disorders, and disorders of skin pigmentation. Conclusion This study indicates a significant reduction in the total number of patients attending dermatology clinics in Egypt during the COVID-19 pandemic. The frequency of some skin diseases increased significantly, whereas other skin diseases decreased significantly or remained unchanged during the pandemic. Periodic evaluation of the epidemiologic characteristics of skin diseases is required at different stages of evolution of the COVID-19 pandemic.","PeriodicalId":40542,"journal":{"name":"Egyptian Journal of Dermatology and Venereology","volume":"42 1","pages":"167 - 173"},"PeriodicalIF":0.4,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49459436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Serum interleukin-33 level and psoriasis diagnosis","authors":"P. Sookaromdee, V. Wiwanitkit","doi":"10.4103/ejdv.ejdv_48_21","DOIUrl":"https://doi.org/10.4103/ejdv.ejdv_48_21","url":null,"abstract":"","PeriodicalId":40542,"journal":{"name":"Egyptian Journal of Dermatology and Venereology","volume":"42 1","pages":"216 - 216"},"PeriodicalIF":0.4,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43726425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Median canaliform dystrophy of Heller is a rare entity characterized by median or midline split of nails in one or both thumb nails. Treatment of median canaliform dystrophy is at times challenging as no successful therapy is available till date. Recently reported treatments include topical steroids, calcineurin inhibitor tacrolimus 0.1%, and tazarotene 0.05% ointment. We report the case of a 30-year-old man who came to our institute with complaints of nail lesions over both thumb nails and great toe nails from the past 5 years, which was causing cosmetic disfigurement.
{"title":"Median canaliform nail dystrophy involving thumb nails and great toe nails: a rare entity","authors":"Vikram Arragudla, A. Parthasaradhi","doi":"10.4103/ejdv.ejdv_30_21","DOIUrl":"https://doi.org/10.4103/ejdv.ejdv_30_21","url":null,"abstract":"Median canaliform dystrophy of Heller is a rare entity characterized by median or midline split of nails in one or both thumb nails. Treatment of median canaliform dystrophy is at times challenging as no successful therapy is available till date. Recently reported treatments include topical steroids, calcineurin inhibitor tacrolimus 0.1%, and tazarotene 0.05% ointment. We report the case of a 30-year-old man who came to our institute with complaints of nail lesions over both thumb nails and great toe nails from the past 5 years, which was causing cosmetic disfigurement.","PeriodicalId":40542,"journal":{"name":"Egyptian Journal of Dermatology and Venereology","volume":"42 1","pages":"206 - 208"},"PeriodicalIF":0.4,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49208750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acne patients demonstrate high levels of social, psychological, and emotional impairment including suicidal ideation. 1 The global pandemic bought with it high levels of psychological distress, and it is well known that stress influences the activity of the pilosebaceous unit leading to acne. 2 Further, “do it yourself” (DIY) solutions flooding the internet meant that it was pertinent that the dermatologist not only initiate care, but administer due counselling and “on-going” care for acne patients at this time. The continuation of care of acne is possible via teledermatology, and it appears to be a common issue for which patients seek video consultations and are satisfied with their initial consult, 3 however video consultation has its limitations.
{"title":"Optimizing acne care via teledermatology − where do we stand?","authors":"Rajat Kandhari","doi":"10.4103/ejdv.ejdv_44_21","DOIUrl":"https://doi.org/10.4103/ejdv.ejdv_44_21","url":null,"abstract":"Acne patients demonstrate high levels of social, psychological, and emotional impairment including suicidal ideation. 1 The global pandemic bought with it high levels of psychological distress, and it is well known that stress influences the activity of the pilosebaceous unit leading to acne. 2 Further, “do it yourself” (DIY) solutions flooding the internet meant that it was pertinent that the dermatologist not only initiate care, but administer due counselling and “on-going” care for acne patients at this time. The continuation of care of acne is possible via teledermatology, and it appears to be a common issue for which patients seek video consultations and are satisfied with their initial consult, 3 however video consultation has its limitations.","PeriodicalId":40542,"journal":{"name":"Egyptian Journal of Dermatology and Venereology","volume":"42 1","pages":"213 - 215"},"PeriodicalIF":0.4,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48827793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rehab Naguib, A. El-Rifaie, Abd-ElA El-Taweel, M. Dahab
Background Psoriasis is a chronic hyperproliferative inflammatory disease, in which genetic and environmental factors have an important role, but the exact cause is yet unknown. Circular RNAs (circRNAs) are regulatory noncoding RNAs. They play an important role in multiple physiological and pathological processes, such as cancer, cardiovascular diseases, and neuronal diseases. Some circRNAs are involved in regulating immunity, inflammation, and cell proliferation in many types of cells. Aim To detect the expression of circRNA (Circ0061012) in psoriatic skin of diseased patients as compared with normal control persons to investigate the possible role of circRNA in psoriasis pathogenesis and its correlation with disease severity. Patients and methods The present study included 30 psoriatic patients and 30 healthy controls. A 4-mm punch skin biopsy was taken from patients (psoriatic lesion) and controls, and it was kept in the lysis solution for the stability of the studied parameters and was kept frozen at ‑80°Celsius till analysis of circRNA by real-time polymerase chain reaction. Results The tissue level of circRNA (Circ0061012) was significantly higher among patients with psoriasis as compared with normal control individuals. Conclusion circRNA could contribute to psoriasis pathogenesis through its immunomodulatory role, so it might be a therapeutic target in the future.
{"title":"An insight into the value of circular RNA in psoriasis pathogenesis and its correlation with PASI score","authors":"Rehab Naguib, A. El-Rifaie, Abd-ElA El-Taweel, M. Dahab","doi":"10.4103/ejdv.ejdv_36_21","DOIUrl":"https://doi.org/10.4103/ejdv.ejdv_36_21","url":null,"abstract":"Background Psoriasis is a chronic hyperproliferative inflammatory disease, in which genetic and environmental factors have an important role, but the exact cause is yet unknown. Circular RNAs (circRNAs) are regulatory noncoding RNAs. They play an important role in multiple physiological and pathological processes, such as cancer, cardiovascular diseases, and neuronal diseases. Some circRNAs are involved in regulating immunity, inflammation, and cell proliferation in many types of cells. Aim To detect the expression of circRNA (Circ0061012) in psoriatic skin of diseased patients as compared with normal control persons to investigate the possible role of circRNA in psoriasis pathogenesis and its correlation with disease severity. Patients and methods The present study included 30 psoriatic patients and 30 healthy controls. A 4-mm punch skin biopsy was taken from patients (psoriatic lesion) and controls, and it was kept in the lysis solution for the stability of the studied parameters and was kept frozen at ‑80°Celsius till analysis of circRNA by real-time polymerase chain reaction. Results The tissue level of circRNA (Circ0061012) was significantly higher among patients with psoriasis as compared with normal control individuals. Conclusion circRNA could contribute to psoriasis pathogenesis through its immunomodulatory role, so it might be a therapeutic target in the future.","PeriodicalId":40542,"journal":{"name":"Egyptian Journal of Dermatology and Venereology","volume":"42 1","pages":"155 - 158"},"PeriodicalIF":0.4,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48838439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rehab Naguib, Abd-ElAziz El-Rifaie, EmanA.Z. Eissa, L. Rashed
Background Psoriasis is a chronic hyperproliferative inflammatory disease, in which genetic and environmental factors have an important role, but the exact cause is yet unknown. Autophagy is a strictly regulated lysosomal degradation pathway that is crucial for maintaining intracellular homeostasis and normal development. Dysregulation of autophagy-related genes has been recognized to increase susceptibility to diseases, such as inflammation, cancer, and autoimmune disorders. Aim Our study aimed to detect the expression of the autophagy-related gene 16L1 (ATG 16L) in psoriasis patients compared with normal controls to investigate the role of autophagy in the pathogenesis of this disease. Patients and methods This case–control study included 30 psoriasis patients and 30 healthy controls. Punch skin biopsies of 4 mm were taken from psoriatic lesions and then from the controls and they were kept in a lysis solution for the stability of the studied parameters and were kept frozen at –80°C till analysis of ATG 16L using real-time PCR. Results The level of the ATG 16L1 in the lesional skin of psoriasis was significantly increased compared with normal controls (P<0.001). Limitation Limited number of patients were included in this study (30 patients). Conclusion Autophagy process may play an important role in the pathogenesis of psoriasis disease.
{"title":"Autophagy-related gene 16L1 value in chronic plaque psoriasis","authors":"Rehab Naguib, Abd-ElAziz El-Rifaie, EmanA.Z. Eissa, L. Rashed","doi":"10.4103/ejdv.ejdv_34_21","DOIUrl":"https://doi.org/10.4103/ejdv.ejdv_34_21","url":null,"abstract":"Background Psoriasis is a chronic hyperproliferative inflammatory disease, in which genetic and environmental factors have an important role, but the exact cause is yet unknown. Autophagy is a strictly regulated lysosomal degradation pathway that is crucial for maintaining intracellular homeostasis and normal development. Dysregulation of autophagy-related genes has been recognized to increase susceptibility to diseases, such as inflammation, cancer, and autoimmune disorders. Aim Our study aimed to detect the expression of the autophagy-related gene 16L1 (ATG 16L) in psoriasis patients compared with normal controls to investigate the role of autophagy in the pathogenesis of this disease. Patients and methods This case–control study included 30 psoriasis patients and 30 healthy controls. Punch skin biopsies of 4 mm were taken from psoriatic lesions and then from the controls and they were kept in a lysis solution for the stability of the studied parameters and were kept frozen at –80°C till analysis of ATG 16L using real-time PCR. Results The level of the ATG 16L1 in the lesional skin of psoriasis was significantly increased compared with normal controls (P<0.001). Limitation Limited number of patients were included in this study (30 patients). Conclusion Autophagy process may play an important role in the pathogenesis of psoriasis disease.","PeriodicalId":40542,"journal":{"name":"Egyptian Journal of Dermatology and Venereology","volume":"42 1","pages":"137 - 140"},"PeriodicalIF":0.4,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48860153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
N. Mohamad, Samar El-Tahlawy, Naglaa A. El Sherbiny, Eman Ebrahim
Background Acanthosis nigricans (AN) is characterized by pigmented velvety thickening of the intertriginous body areas and neck. Many studies linked it to metabolic syndrome. Aim To detect the prevalence of AN among primary school children and to identify the associated risk factors. Patients and methods We included 2060 primary school students who were selected from two rural and four urban schools. The data were collected by questionnaire sheets that were fulfilled from each student in which present and past history for any disease were taken. Results The prevalence of AN was 17.7% of all examined students, higher in females (18.6%) than males (16.3%), but it was not statistically significant. More than half of the students 55.0% were of normal weight, 23.3% were overweight, and 21.7% were obese. In the current study, 69.1% of obese children were having AN. Conclusions Regular dermatologic examination for early identification of AN is required. AN in the knuckles should be considered as a classic site and highly prevalent. It should be borne in mind that coordinated efforts of medical professional teams may be required aiming to correct the underlying disease to improve the skin symptoms. Strict follow-up of patients with AN for early detection and management of insulin resistance and metabolic syndrome.
{"title":"Prevalence and risk factors associated with acanthosis nigricans in primary school children","authors":"N. Mohamad, Samar El-Tahlawy, Naglaa A. El Sherbiny, Eman Ebrahim","doi":"10.4103/ejdv.ejdv_16_21","DOIUrl":"https://doi.org/10.4103/ejdv.ejdv_16_21","url":null,"abstract":"Background Acanthosis nigricans (AN) is characterized by pigmented velvety thickening of the intertriginous body areas and neck. Many studies linked it to metabolic syndrome. Aim To detect the prevalence of AN among primary school children and to identify the associated risk factors. Patients and methods We included 2060 primary school students who were selected from two rural and four urban schools. The data were collected by questionnaire sheets that were fulfilled from each student in which present and past history for any disease were taken. Results The prevalence of AN was 17.7% of all examined students, higher in females (18.6%) than males (16.3%), but it was not statistically significant. More than half of the students 55.0% were of normal weight, 23.3% were overweight, and 21.7% were obese. In the current study, 69.1% of obese children were having AN. Conclusions Regular dermatologic examination for early identification of AN is required. AN in the knuckles should be considered as a classic site and highly prevalent. It should be borne in mind that coordinated efforts of medical professional teams may be required aiming to correct the underlying disease to improve the skin symptoms. Strict follow-up of patients with AN for early detection and management of insulin resistance and metabolic syndrome.","PeriodicalId":40542,"journal":{"name":"Egyptian Journal of Dermatology and Venereology","volume":"42 1","pages":"97 - 102"},"PeriodicalIF":0.4,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41372002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Noha Z Tawfik, A. Gomaa, Ranya Hassan, Basma El-alfy, Sara Rageh, N. Ismail
Background Psoriasis is a chronic multifactorial autoimmune disease that has significant impacts on the quality of life. Adiponectin exhibits important anti-inflammatory, antioxidants, and antidiabetic effects. The role of fatty acid-binding protein 4 (FABP4) in psoriasis may be linked to tumor necrosis factor-α, which is one of the main cytokines contributing to the etiopathogenesis of this disease. Aim To understand the role of serum levels of FABP4 and adiponectin in disease pathogenesis and their correlation to disease severity. Patients and methods A case–control study was conducted on two groups. The first group included 35 psoriatic patients; the second group included 35 healthy volunteers matched for age, sex, and weight. Serum FABP4 and adiponectin levels were evaluated. Results The mean level of adiponectin among the patients was 4.3±1.4 ng/dl. The mean level of FABP4 among controls was 2.1±1.5 ng/dl. The difference between both groups was statistically significant (P<0.05). Conclusion In this study, serum FABP4 level and adiponectin levels were decreased in patients with psoriasis with no relation to disease severity. So, they cannot be used as clinical biomarkers of inflammation and disease activity in psoriasis
{"title":"Assessment of serum fatty acid-binding protein 4 and adiponectin levels in psoriasis patients and their correlation with disease severity","authors":"Noha Z Tawfik, A. Gomaa, Ranya Hassan, Basma El-alfy, Sara Rageh, N. Ismail","doi":"10.4103/ejdv.ejdv_40_21","DOIUrl":"https://doi.org/10.4103/ejdv.ejdv_40_21","url":null,"abstract":"Background Psoriasis is a chronic multifactorial autoimmune disease that has significant impacts on the quality of life. Adiponectin exhibits important anti-inflammatory, antioxidants, and antidiabetic effects. The role of fatty acid-binding protein 4 (FABP4) in psoriasis may be linked to tumor necrosis factor-α, which is one of the main cytokines contributing to the etiopathogenesis of this disease. Aim To understand the role of serum levels of FABP4 and adiponectin in disease pathogenesis and their correlation to disease severity. Patients and methods A case–control study was conducted on two groups. The first group included 35 psoriatic patients; the second group included 35 healthy volunteers matched for age, sex, and weight. Serum FABP4 and adiponectin levels were evaluated. Results The mean level of adiponectin among the patients was 4.3±1.4 ng/dl. The mean level of FABP4 among controls was 2.1±1.5 ng/dl. The difference between both groups was statistically significant (P<0.05). Conclusion In this study, serum FABP4 level and adiponectin levels were decreased in patients with psoriasis with no relation to disease severity. So, they cannot be used as clinical biomarkers of inflammation and disease activity in psoriasis","PeriodicalId":40542,"journal":{"name":"Egyptian Journal of Dermatology and Venereology","volume":"42 1","pages":"110 - 114"},"PeriodicalIF":0.4,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48920247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objectives To know the prevalence and clinical patterns of infant dermatosis at a tertiary care referral institute. Patients and methods The present observational cross-sectional study was carried out on 508 neonates and infants with physiological and pathological skin conditions from August 1, 2018 to February 1, 2020. A standard study proforma was used to obtain detailed systemic and dermatological findings. Data entry was done in MS Excel, and data analysis was carried out using Statistical Package for Social Sciences, version 22.0. Results The common dermatoses were bacterial infection [folliculitis (29.03%) and staphylococcal scalded skin syndrome (19.35%)], fungal infections [candidal intertrigo (41.67%) and pityriasis versicolor (37.50%)], developmental abnormalities [accessory tragi (21.43%), anencephaly (14.29%), and cleft lip (14.29%)], diaper area eruptions [diaper dermatitis (81.82%), atopic dermatitis (45.92%), hemangiomas: infantile congenital hemangioma (60.87%) and nevus simplex/stork bite (21.74%)], hyperpigmentation disorders [Café-au-lait (44.44%) and congenital melanocytic nevi (22.22%)], hypopigmentation disorder [pityriasis alba (42.31%)], iatrogenic/traumatic disorders [Stevens-Johnson syndrome (40%)], immunologic disorders [insect bite hypersensitivity (41.18%) and acute urticaria (29.41%)], and transient benign disorders [Mongolian spots (23.28%) and Lanugo (14.29%)]. Conclusion Physiological dermatoses are transient and self-resolving and need to be differentiated from the pathological ones for management and parents’ reassurance. The pathological dermatoses are caused most commonly by infections and infestation, which warrants a clean and hygienic living. Owing to wide variety, burden, and public health problem of cutaneous dermatoses in infants, the current data can be useful in creating awareness among the dermatologists, pediatricians, and the health care system.
{"title":"An observational study of infant dermatoses at a tertiary care health center in Delhi region","authors":"A. Dhillon, A. Chopra","doi":"10.4103/ejdv.ejdv_21_21","DOIUrl":"https://doi.org/10.4103/ejdv.ejdv_21_21","url":null,"abstract":"Objectives To know the prevalence and clinical patterns of infant dermatosis at a tertiary care referral institute. Patients and methods The present observational cross-sectional study was carried out on 508 neonates and infants with physiological and pathological skin conditions from August 1, 2018 to February 1, 2020. A standard study proforma was used to obtain detailed systemic and dermatological findings. Data entry was done in MS Excel, and data analysis was carried out using Statistical Package for Social Sciences, version 22.0. Results The common dermatoses were bacterial infection [folliculitis (29.03%) and staphylococcal scalded skin syndrome (19.35%)], fungal infections [candidal intertrigo (41.67%) and pityriasis versicolor (37.50%)], developmental abnormalities [accessory tragi (21.43%), anencephaly (14.29%), and cleft lip (14.29%)], diaper area eruptions [diaper dermatitis (81.82%), atopic dermatitis (45.92%), hemangiomas: infantile congenital hemangioma (60.87%) and nevus simplex/stork bite (21.74%)], hyperpigmentation disorders [Café-au-lait (44.44%) and congenital melanocytic nevi (22.22%)], hypopigmentation disorder [pityriasis alba (42.31%)], iatrogenic/traumatic disorders [Stevens-Johnson syndrome (40%)], immunologic disorders [insect bite hypersensitivity (41.18%) and acute urticaria (29.41%)], and transient benign disorders [Mongolian spots (23.28%) and Lanugo (14.29%)]. Conclusion Physiological dermatoses are transient and self-resolving and need to be differentiated from the pathological ones for management and parents’ reassurance. The pathological dermatoses are caused most commonly by infections and infestation, which warrants a clean and hygienic living. Owing to wide variety, burden, and public health problem of cutaneous dermatoses in infants, the current data can be useful in creating awareness among the dermatologists, pediatricians, and the health care system.","PeriodicalId":40542,"journal":{"name":"Egyptian Journal of Dermatology and Venereology","volume":"42 1","pages":"115 - 126"},"PeriodicalIF":0.4,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44970698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Unusual Triggers for Erythema Multiforme","authors":"Manal Alsabbagh","doi":"10.4103/ejdv.ejdv_20_21","DOIUrl":"https://doi.org/10.4103/ejdv.ejdv_20_21","url":null,"abstract":"","PeriodicalId":40542,"journal":{"name":"Egyptian Journal of Dermatology and Venereology","volume":"42 1","pages":"148 - 150"},"PeriodicalIF":0.4,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45362347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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