H. Khaled, R. El-Helbawy, E. E. El Gayed, A. Khalaf
{"title":"Hypogonadism in men with obstructive sleep apnea and its related risk factors","authors":"H. Khaled, R. El-Helbawy, E. E. El Gayed, A. Khalaf","doi":"10.4103/ejdv.ejdv_40_22","DOIUrl":"https://doi.org/10.4103/ejdv.ejdv_40_22","url":null,"abstract":"","PeriodicalId":40542,"journal":{"name":"Egyptian Journal of Dermatology and Venereology","volume":"1 1","pages":""},"PeriodicalIF":0.4,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70716928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Verrucous squamous cell carcinoma occurring as a complication of generalized discoid lupus erythematosus in a nonsmoker: a rare entity","authors":"Mallick Subhadeep, Baisya Subhasmita, H. Arpita, Mondal Nirjhar, Rudra Olympia, Chatterjee Gobinda","doi":"10.4103/ejdv.ejdv_25_22","DOIUrl":"https://doi.org/10.4103/ejdv.ejdv_25_22","url":null,"abstract":"","PeriodicalId":40542,"journal":{"name":"Egyptian Journal of Dermatology and Venereology","volume":"154 1","pages":""},"PeriodicalIF":0.4,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70715908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Mohamed, WafaaM.A El-Magid, NoreenI Abd-Elghany, R. Saleh
{"title":"Efficacy of combination therapy with microneedling and topical latanoprost 0.005% in treatment of acrofacial vitiligo: a randomized controlled trial","authors":"M. Mohamed, WafaaM.A El-Magid, NoreenI Abd-Elghany, R. Saleh","doi":"10.4103/ejdv.ejdv_41_22","DOIUrl":"https://doi.org/10.4103/ejdv.ejdv_41_22","url":null,"abstract":"","PeriodicalId":40542,"journal":{"name":"Egyptian Journal of Dermatology and Venereology","volume":"1 1","pages":""},"PeriodicalIF":0.4,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70716576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Tabari, M. Motahari, Mohammad Ranaee, H. Gholinia, S. Moudi
Introduction Skin and soft tissue disorders are common problems in patients with substance use. This research was conducted to assess the different types of skin and soft tissue problems in patients with substance use disorders. Patients and methods This observational research was conducted as a cross-sectional study among patients with substance use disorders, who were referred to governmental methadone maintenance treatment centers affiliated to Babol University of Medical Sciences, North of Iran. The patients were assessed by the research dermatologist and a psychiatrist. During a complete physical examination of the skin, hair, and nails and, if necessary, a biopsy of suspected lesions, various skin and soft tissue disorders were identified and classified. Results In total, 197 patients (188 men and nine women) with a mean age of 43.74±12.94 years were included in the research. Following complete examination, 10 (5.1%) patients with skin and soft tissue disorders were identified, of which three (30%) had pruritic eczema, two (20%) had psoriasis, one (10%) patient vitiligo, one (10%) had eczema with vasculitis, one (10%) had scarring and seborrheic keratosis, and two (20%) patients had inflammatory lesions. No significant association was found between skin disorders and age (P=0.14), sex (P=0.99), marital status (P=0.32), level of education (P=0.81), occupation (P=0.70), and living condition (P=0.23). Patients with heroin use had a significant difference with other substance users on the occurrence of skin disorders (P<0.001). Conclusions Dermatologic disorders should be considered in individuals with substance use disorders. Periodic skin examination of these patients is recommended.
{"title":"Skin and soft tissue disorders in patients with substance-use disorders","authors":"S. Tabari, M. Motahari, Mohammad Ranaee, H. Gholinia, S. Moudi","doi":"10.4103/ejdv.ejdv_18_22","DOIUrl":"https://doi.org/10.4103/ejdv.ejdv_18_22","url":null,"abstract":"Introduction Skin and soft tissue disorders are common problems in patients with substance use. This research was conducted to assess the different types of skin and soft tissue problems in patients with substance use disorders. Patients and methods This observational research was conducted as a cross-sectional study among patients with substance use disorders, who were referred to governmental methadone maintenance treatment centers affiliated to Babol University of Medical Sciences, North of Iran. The patients were assessed by the research dermatologist and a psychiatrist. During a complete physical examination of the skin, hair, and nails and, if necessary, a biopsy of suspected lesions, various skin and soft tissue disorders were identified and classified. Results In total, 197 patients (188 men and nine women) with a mean age of 43.74±12.94 years were included in the research. Following complete examination, 10 (5.1%) patients with skin and soft tissue disorders were identified, of which three (30%) had pruritic eczema, two (20%) had psoriasis, one (10%) patient vitiligo, one (10%) had eczema with vasculitis, one (10%) had scarring and seborrheic keratosis, and two (20%) patients had inflammatory lesions. No significant association was found between skin disorders and age (P=0.14), sex (P=0.99), marital status (P=0.32), level of education (P=0.81), occupation (P=0.70), and living condition (P=0.23). Patients with heroin use had a significant difference with other substance users on the occurrence of skin disorders (P<0.001). Conclusions Dermatologic disorders should be considered in individuals with substance use disorders. Periodic skin examination of these patients is recommended.","PeriodicalId":40542,"journal":{"name":"Egyptian Journal of Dermatology and Venereology","volume":"43 1","pages":"62 - 66"},"PeriodicalIF":0.4,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42676116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Aboeldahab, M. El-Hamd, Rehab Hamed Bakla, Essam El-Din Abdel-Aziz Nada
Background Psoriasis is a common and complex multifactorial disease, in which both genetic and extrinsic factors contribute to activating an immunological reaction. Objectives This study aimed to evaluate the clinical, demographic, and laboratory characteristics of Egyptian psoriatic patients in Sohag, Upper Egypt. Patients and methods This study was a cross-sectional hospital-based study conducted on 200 Egyptian psoriatic patients. All the patients were subjected to complete demographic, clinical, and laboratory evaluations. Results Of the 200 Egyptian patients with psoriasis, the mean age was 42.83±17.3 years; 60% were males, 53% were from rural areas, 47% were smokers, 66% were with positive family history, 91% were with gradual onset, 75% were with a progressive course, and 6.99±3.9 months was the mean duration of the diseases. The main associated symptom with psoriasis was itching in 72%. Psoriasis vulgaris was the most common type in 69.5%. Upper limbs were the most commonly affected sites in 78% of the psoriatic patients. Seasonal variation was the most common exacerbating factor in 51.5% of psoriatic patients. Iron-deficiency anemia was detected in 31% of the psoriatic patients. Liver diseases were associated comorbidities with 29.5% of psoriatic patients and hepatitis C virus infection was presented in 4.5% of psoriatic patients. Metabolic syndrome and stress were detected in 36 and 21% of psoriatic patients, respectively. Conclusion The healthcare providers and patients should be aware of the early detection of associated comorbidities with psoriasis to avoid major complications. The recognition of stress and its specific treatment should be considered an integral part of the treatment of psoriatic patients. Screening for hepatitis is important in Egyptian psoriatic patients. Consanguineous marriage should be avoided in patients with a family history of psoriasis.
{"title":"Clinicodemographic and laboratory features of 200 Egyptian psoriatic patients","authors":"S. Aboeldahab, M. El-Hamd, Rehab Hamed Bakla, Essam El-Din Abdel-Aziz Nada","doi":"10.4103/ejdv.ejdv_9_22","DOIUrl":"https://doi.org/10.4103/ejdv.ejdv_9_22","url":null,"abstract":"Background Psoriasis is a common and complex multifactorial disease, in which both genetic and extrinsic factors contribute to activating an immunological reaction. Objectives This study aimed to evaluate the clinical, demographic, and laboratory characteristics of Egyptian psoriatic patients in Sohag, Upper Egypt. Patients and methods This study was a cross-sectional hospital-based study conducted on 200 Egyptian psoriatic patients. All the patients were subjected to complete demographic, clinical, and laboratory evaluations. Results Of the 200 Egyptian patients with psoriasis, the mean age was 42.83±17.3 years; 60% were males, 53% were from rural areas, 47% were smokers, 66% were with positive family history, 91% were with gradual onset, 75% were with a progressive course, and 6.99±3.9 months was the mean duration of the diseases. The main associated symptom with psoriasis was itching in 72%. Psoriasis vulgaris was the most common type in 69.5%. Upper limbs were the most commonly affected sites in 78% of the psoriatic patients. Seasonal variation was the most common exacerbating factor in 51.5% of psoriatic patients. Iron-deficiency anemia was detected in 31% of the psoriatic patients. Liver diseases were associated comorbidities with 29.5% of psoriatic patients and hepatitis C virus infection was presented in 4.5% of psoriatic patients. Metabolic syndrome and stress were detected in 36 and 21% of psoriatic patients, respectively. Conclusion The healthcare providers and patients should be aware of the early detection of associated comorbidities with psoriasis to avoid major complications. The recognition of stress and its specific treatment should be considered an integral part of the treatment of psoriatic patients. Screening for hepatitis is important in Egyptian psoriatic patients. Consanguineous marriage should be avoided in patients with a family history of psoriasis.","PeriodicalId":40542,"journal":{"name":"Egyptian Journal of Dermatology and Venereology","volume":"43 1","pages":"15 - 23"},"PeriodicalIF":0.4,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47627166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Herpes zoster duplex bilateralis asymmetrica: a rare presentation in an immunocompetent individual","authors":"M. Bhalla, A. Arora, Monika Kucheria","doi":"10.4103/ejdv.ejdv_20_22","DOIUrl":"https://doi.org/10.4103/ejdv.ejdv_20_22","url":null,"abstract":"","PeriodicalId":40542,"journal":{"name":"Egyptian Journal of Dermatology and Venereology","volume":"1 1","pages":""},"PeriodicalIF":0.4,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70715079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Werner syndrome, a premature aging disorder, is a rare cause of pseudoscleroderma and can present with a multitude of clinical features involving the skin, endocrine and cardiovascular systems. Although genetic, the disease has its onset in puberty and cutaneous features like graying of hair, atrophic sclerotic skin, recurrent ulcers, and dyspigmentation are the first to manifest. All these features usually mislead the clinician to make a diagnosis of systemic sclerosis. A similar case is being presented and the importance of differentiating these two disorders is being discussed.
{"title":"Werner syndrome or adult progeria: a rare scleroderma mimicker","authors":"Jasleen Sandhu, Ankita Tuknayat","doi":"10.4103/ejdv.ejdv_12_22","DOIUrl":"https://doi.org/10.4103/ejdv.ejdv_12_22","url":null,"abstract":"Werner syndrome, a premature aging disorder, is a rare cause of pseudoscleroderma and can present with a multitude of clinical features involving the skin, endocrine and cardiovascular systems. Although genetic, the disease has its onset in puberty and cutaneous features like graying of hair, atrophic sclerotic skin, recurrent ulcers, and dyspigmentation are the first to manifest. All these features usually mislead the clinician to make a diagnosis of systemic sclerosis. A similar case is being presented and the importance of differentiating these two disorders is being discussed.","PeriodicalId":40542,"journal":{"name":"Egyptian Journal of Dermatology and Venereology","volume":"43 1","pages":"75 - 78"},"PeriodicalIF":0.4,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46866763","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
W. Abd-Elmagid, Dalia Hagag, S. Sayed, Sahar Aboelfetoh, R. Saleh
Background Autoimmunity is the most commonly accepted theory in the pathogenesis of vitiligo. This is supported by the association of vitiligo with many other autoimmune diseases, such as Hashimoto thyroiditis and Graves’ disease. Aim The aim of this study was to investigate the laboratory profiles of a cohort of patients with nonsegmental vitiligo (NSV). Patients and methods This cross-sectional study included 100 patients with NSV and 100 age-matched and sex-matched healthy volunteers as controls. Laboratory workup included thyroid-stimulating hormone, triiodothyronine, thyroxine, free thyroxine, antithyroid peroxidase antibody, antithyroglobulin antibody, and antinuclear antibody (ANA). Results Thyroid-stimulating hormone, triiodothyronine, and thyroxine showed a significant difference between patients with vitiligo and control (P=0.007). There was a statistically significant increase in the level of antithyroid peroxidase antibody (P=0.000) and antithyroglobulin antibody (P=0.000) antibodies in patients with NSV. Conclusion NSV is associated with disturbance of thyroid function tests and significant increase of thyroid autoantibodies.
{"title":"Alterations of thyroid functions in patients with nonsegmental vitiligo: a cross-sectional study","authors":"W. Abd-Elmagid, Dalia Hagag, S. Sayed, Sahar Aboelfetoh, R. Saleh","doi":"10.4103/ejdv.ejdv_22_22","DOIUrl":"https://doi.org/10.4103/ejdv.ejdv_22_22","url":null,"abstract":"Background Autoimmunity is the most commonly accepted theory in the pathogenesis of vitiligo. This is supported by the association of vitiligo with many other autoimmune diseases, such as Hashimoto thyroiditis and Graves’ disease. Aim The aim of this study was to investigate the laboratory profiles of a cohort of patients with nonsegmental vitiligo (NSV). Patients and methods This cross-sectional study included 100 patients with NSV and 100 age-matched and sex-matched healthy volunteers as controls. Laboratory workup included thyroid-stimulating hormone, triiodothyronine, thyroxine, free thyroxine, antithyroid peroxidase antibody, antithyroglobulin antibody, and antinuclear antibody (ANA). Results Thyroid-stimulating hormone, triiodothyronine, and thyroxine showed a significant difference between patients with vitiligo and control (P=0.007). There was a statistically significant increase in the level of antithyroid peroxidase antibody (P=0.000) and antithyroglobulin antibody (P=0.000) antibodies in patients with NSV. Conclusion NSV is associated with disturbance of thyroid function tests and significant increase of thyroid autoantibodies.","PeriodicalId":40542,"journal":{"name":"Egyptian Journal of Dermatology and Venereology","volume":"43 1","pages":"55 - 61"},"PeriodicalIF":0.4,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48916411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
I. Ezejiofor, Olaniyi Olaofe, O. Ezejiofor, C. Ukah, N. Ozor, AdeizaS Enesi, ChukwuemekaN Osonwa
{"title":"Histopathologic profile of cutaneous cystic lesions in teaching hospital, Nnewi, South-east, Nigeria: a 9-year Review","authors":"I. Ezejiofor, Olaniyi Olaofe, O. Ezejiofor, C. Ukah, N. Ozor, AdeizaS Enesi, ChukwuemekaN Osonwa","doi":"10.4103/ejdv.ejdv_34_22","DOIUrl":"https://doi.org/10.4103/ejdv.ejdv_34_22","url":null,"abstract":"","PeriodicalId":40542,"journal":{"name":"Egyptian Journal of Dermatology and Venereology","volume":"1 1","pages":""},"PeriodicalIF":0.4,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70716764","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Chavhan, Sugat A Jawade, Bhushan Madke, A. Singh
Background There is paucity of Indian studies on comprehensive assessment of systemic comorbidities in psoriasis. This study aimed at assessing the systemic comorbidities in patients of psoriasis in India. Patients and methods A case–control study was conducted from September 2019 to August 2021. Study participants of more than 18 years, with 30 psoriasis patients as cases and 30 healthy individuals as controls. Assessment of Psoriasis Area Severity Index in cases, BMI, waist circumference, blood pressure, and detailed systemic index evaluation was done in both the groups. Analyses were done using χ2 test and independent t test. Analysis of variance test is used to compare continuous variables among more than two groups. Odds ratio (OR) and 95% confidence interval were calculated. Results The mean age of psoriasis cases was 45.03±13.1 years with 73.3% of male and 26.7% of female population. Mean duration of psoriasis observed is 6.9±4.2 years with the mean Psoriasis Area Severity Index of 17.73±6.389. Comparison of systemic indices demonstrated significant increase in neutrophil count (P=0.006), erythrocyte-sedimentation rate (P<0.0001), glycated hemoglobin (P=0.037), low-density lipoprotein (P=0.0418), T3 (P<0.0001), and T4 (P=0.018). No significant difference in the liver-function test and renal-function test was seen in both the groups. Comparison of the prevalence of diseases associated with psoriasis, shows that the prevalence of metabolic syndrome (60 vs. 30%, OR=3.5, P=0.021), nonalcoholic fatty liver disease (26.6 vs. 6.6%, P=0.002, OR=14), increase in the carotid artery intimal thickness on both sides (right P=0.007, OR=5; left P=0.005, OR=7), and the inflammatory marker C-reactive protein (70 vs. 33.3%, P=0.005, OR=4.66) is significantly increased in cases as compared with controls. Other diseases like obesity (BMI: OR=2.0417, P=0.187; waist circumference: OR=2.25, P=0.123), type-2 diabetes mellitus (P=0.56, OR=1.40), hypertension (P=0.78, OR=1.15), and renal disease (P=1, OR=1) is found to have greater risk in psoriasis patients than controls, but the reflecting difference is not statistically significant. Conclusion The study revealed that the patients of psoriasis are more likely to have systemic comorbidities as compared with patients without psoriasis.
{"title":"Systemic comorbidities in patients of psoriasis: a case–control study from India","authors":"S. Chavhan, Sugat A Jawade, Bhushan Madke, A. Singh","doi":"10.4103/ejdv.ejdv_15_22","DOIUrl":"https://doi.org/10.4103/ejdv.ejdv_15_22","url":null,"abstract":"Background There is paucity of Indian studies on comprehensive assessment of systemic comorbidities in psoriasis. This study aimed at assessing the systemic comorbidities in patients of psoriasis in India. Patients and methods A case–control study was conducted from September 2019 to August 2021. Study participants of more than 18 years, with 30 psoriasis patients as cases and 30 healthy individuals as controls. Assessment of Psoriasis Area Severity Index in cases, BMI, waist circumference, blood pressure, and detailed systemic index evaluation was done in both the groups. Analyses were done using χ2 test and independent t test. Analysis of variance test is used to compare continuous variables among more than two groups. Odds ratio (OR) and 95% confidence interval were calculated. Results The mean age of psoriasis cases was 45.03±13.1 years with 73.3% of male and 26.7% of female population. Mean duration of psoriasis observed is 6.9±4.2 years with the mean Psoriasis Area Severity Index of 17.73±6.389. Comparison of systemic indices demonstrated significant increase in neutrophil count (P=0.006), erythrocyte-sedimentation rate (P<0.0001), glycated hemoglobin (P=0.037), low-density lipoprotein (P=0.0418), T3 (P<0.0001), and T4 (P=0.018). No significant difference in the liver-function test and renal-function test was seen in both the groups. Comparison of the prevalence of diseases associated with psoriasis, shows that the prevalence of metabolic syndrome (60 vs. 30%, OR=3.5, P=0.021), nonalcoholic fatty liver disease (26.6 vs. 6.6%, P=0.002, OR=14), increase in the carotid artery intimal thickness on both sides (right P=0.007, OR=5; left P=0.005, OR=7), and the inflammatory marker C-reactive protein (70 vs. 33.3%, P=0.005, OR=4.66) is significantly increased in cases as compared with controls. Other diseases like obesity (BMI: OR=2.0417, P=0.187; waist circumference: OR=2.25, P=0.123), type-2 diabetes mellitus (P=0.56, OR=1.40), hypertension (P=0.78, OR=1.15), and renal disease (P=1, OR=1) is found to have greater risk in psoriasis patients than controls, but the reflecting difference is not statistically significant. Conclusion The study revealed that the patients of psoriasis are more likely to have systemic comorbidities as compared with patients without psoriasis.","PeriodicalId":40542,"journal":{"name":"Egyptian Journal of Dermatology and Venereology","volume":"43 1","pages":"67 - 74"},"PeriodicalIF":0.4,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45095587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}