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Egyptian Journal of Dermatology and Venereology最新文献

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Hypogonadism in men with obstructive sleep apnea and its related risk factors 男性阻塞性睡眠呼吸暂停患者性腺功能减退及其相关危险因素
IF 0.4 Q4 DERMATOLOGY Pub Date : 2023-01-01 DOI: 10.4103/ejdv.ejdv_40_22
H. Khaled, R. El-Helbawy, E. E. El Gayed, A. Khalaf
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引用次数: 0
Verrucous squamous cell carcinoma occurring as a complication of generalized discoid lupus erythematosus in a nonsmoker: a rare entity 疣状鳞状细胞癌在非吸烟者中作为全身性盘状红斑狼疮的并发症:一种罕见的实体
IF 0.4 Q4 DERMATOLOGY Pub Date : 2023-01-01 DOI: 10.4103/ejdv.ejdv_25_22
Mallick Subhadeep, Baisya Subhasmita, H. Arpita, Mondal Nirjhar, Rudra Olympia, Chatterjee Gobinda
{"title":"Verrucous squamous cell carcinoma occurring as a complication of generalized discoid lupus erythematosus in a nonsmoker: a rare entity","authors":"Mallick Subhadeep, Baisya Subhasmita, H. Arpita, Mondal Nirjhar, Rudra Olympia, Chatterjee Gobinda","doi":"10.4103/ejdv.ejdv_25_22","DOIUrl":"https://doi.org/10.4103/ejdv.ejdv_25_22","url":null,"abstract":"","PeriodicalId":40542,"journal":{"name":"Egyptian Journal of Dermatology and Venereology","volume":"154 1","pages":""},"PeriodicalIF":0.4,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70715908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Efficacy of combination therapy with microneedling and topical latanoprost 0.005% in treatment of acrofacial vitiligo: a randomized controlled trial 微针联合0.005%拉坦前列素治疗面部面部白癜风的疗效:一项随机对照试验
IF 0.4 Q4 DERMATOLOGY Pub Date : 2023-01-01 DOI: 10.4103/ejdv.ejdv_41_22
M. Mohamed, WafaaM.A El-Magid, NoreenI Abd-Elghany, R. Saleh
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引用次数: 0
Skin and soft tissue disorders in patients with substance-use disorders 物质使用障碍患者的皮肤和软组织疾病
IF 0.4 Q4 DERMATOLOGY Pub Date : 2023-01-01 DOI: 10.4103/ejdv.ejdv_18_22
S. Tabari, M. Motahari, Mohammad Ranaee, H. Gholinia, S. Moudi
Introduction Skin and soft tissue disorders are common problems in patients with substance use. This research was conducted to assess the different types of skin and soft tissue problems in patients with substance use disorders. Patients and methods This observational research was conducted as a cross-sectional study among patients with substance use disorders, who were referred to governmental methadone maintenance treatment centers affiliated to Babol University of Medical Sciences, North of Iran. The patients were assessed by the research dermatologist and a psychiatrist. During a complete physical examination of the skin, hair, and nails and, if necessary, a biopsy of suspected lesions, various skin and soft tissue disorders were identified and classified. Results In total, 197 patients (188 men and nine women) with a mean age of 43.74±12.94 years were included in the research. Following complete examination, 10 (5.1%) patients with skin and soft tissue disorders were identified, of which three (30%) had pruritic eczema, two (20%) had psoriasis, one (10%) patient vitiligo, one (10%) had eczema with vasculitis, one (10%) had scarring and seborrheic keratosis, and two (20%) patients had inflammatory lesions. No significant association was found between skin disorders and age (P=0.14), sex (P=0.99), marital status (P=0.32), level of education (P=0.81), occupation (P=0.70), and living condition (P=0.23). Patients with heroin use had a significant difference with other substance users on the occurrence of skin disorders (P<0.001). Conclusions Dermatologic disorders should be considered in individuals with substance use disorders. Periodic skin examination of these patients is recommended.
皮肤和软组织紊乱是药物使用患者的常见问题。本研究旨在评估药物使用障碍患者不同类型的皮肤和软组织问题。患者和方法本观察性研究是在伊朗北部巴博勒医学大学附属政府美沙酮维持治疗中心的物质使用障碍患者中进行的横断面研究。研究皮肤科医生和精神病医生对患者进行了评估。在对皮肤、头发和指甲进行全面体检期间,如有必要,对疑似病变进行活组织检查,确定并分类了各种皮肤和软组织疾病。结果共纳入197例患者(男188例,女9例),平均年龄43.74±12.94岁。经全面检查,发现10例(5.1%)皮肤软组织病变患者,其中瘙痒性湿疹3例(30%),牛皮癣2例(20%),白癜风1例(10%),湿疹合并血管炎1例(10%),瘢痕及脂溢性角化病1例(10%),炎性病变2例(20%)。皮肤疾病与年龄(P=0.14)、性别(P=0.99)、婚姻状况(P=0.32)、文化程度(P=0.81)、职业(P=0.70)、生活条件(P=0.23)无显著相关性。海洛因使用者与其他物质使用者在皮肤疾患的发生率上有显著差异(P<0.001)。结论药物使用障碍患者应考虑皮肤疾病。建议对这些患者进行定期皮肤检查。
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引用次数: 0
Clinicodemographic and laboratory features of 200 Egyptian psoriatic patients 200例埃及银屑病患者的临床病理和实验室特征
IF 0.4 Q4 DERMATOLOGY Pub Date : 2023-01-01 DOI: 10.4103/ejdv.ejdv_9_22
S. Aboeldahab, M. El-Hamd, Rehab Hamed Bakla, Essam El-Din Abdel-Aziz Nada
Background Psoriasis is a common and complex multifactorial disease, in which both genetic and extrinsic factors contribute to activating an immunological reaction. Objectives This study aimed to evaluate the clinical, demographic, and laboratory characteristics of Egyptian psoriatic patients in Sohag, Upper Egypt. Patients and methods This study was a cross-sectional hospital-based study conducted on 200 Egyptian psoriatic patients. All the patients were subjected to complete demographic, clinical, and laboratory evaluations. Results Of the 200 Egyptian patients with psoriasis, the mean age was 42.83±17.3 years; 60% were males, 53% were from rural areas, 47% were smokers, 66% were with positive family history, 91% were with gradual onset, 75% were with a progressive course, and 6.99±3.9 months was the mean duration of the diseases. The main associated symptom with psoriasis was itching in 72%. Psoriasis vulgaris was the most common type in 69.5%. Upper limbs were the most commonly affected sites in 78% of the psoriatic patients. Seasonal variation was the most common exacerbating factor in 51.5% of psoriatic patients. Iron-deficiency anemia was detected in 31% of the psoriatic patients. Liver diseases were associated comorbidities with 29.5% of psoriatic patients and hepatitis C virus infection was presented in 4.5% of psoriatic patients. Metabolic syndrome and stress were detected in 36 and 21% of psoriatic patients, respectively. Conclusion The healthcare providers and patients should be aware of the early detection of associated comorbidities with psoriasis to avoid major complications. The recognition of stress and its specific treatment should be considered an integral part of the treatment of psoriatic patients. Screening for hepatitis is important in Egyptian psoriatic patients. Consanguineous marriage should be avoided in patients with a family history of psoriasis.
背景银屑病是一种常见而复杂的多因素疾病,遗传和外源因素都有助于激活免疫反应。目的本研究旨在评估上埃及Sohag埃及银屑病患者的临床、人口统计学和实验室特征。患者和方法本研究是一项基于医院的横断面研究,对200名埃及银屑病患者进行了研究。所有患者都接受了完整的人口统计学、临床和实验室评估。结果埃及银屑病患者200例,平均年龄42.83±17.3岁;60%为男性,53%来自农村,47%为吸烟者,66%有阳性家族史,91%为渐进性发作,75%为渐进性病程,平均病程为6.99±3.9个月。银屑病的主要相关症状是瘙痒,占72%。寻常型银屑病最常见,占69.5%。78%的银屑病患者上肢是最常见的发病部位。在51.5%的银屑病患者中,季节变化是最常见的加重因素。31%的银屑病患者出现了缺铁性贫血。29.5%的银屑病患者合并肝脏疾病,4.5%的银屑病患者出现丙型肝炎病毒感染。代谢综合征和应激分别在36%和21%的银屑病患者中检测到。结论医护人员和患者应注意银屑病合并症的早期发现,避免出现重大并发症。对压力的认识及其具体治疗应被视为银屑病患者治疗的一个组成部分。对埃及银屑病患者进行肝炎筛查很重要。有银屑病家族史的患者应避免近亲结婚。
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引用次数: 0
Herpes zoster duplex bilateralis asymmetrica: a rare presentation in an immunocompetent individual 双侧不对称带状疱疹:在免疫能力强的个体中罕见的表现
IF 0.4 Q4 DERMATOLOGY Pub Date : 2023-01-01 DOI: 10.4103/ejdv.ejdv_20_22
M. Bhalla, A. Arora, Monika Kucheria
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引用次数: 0
Werner syndrome or adult progeria: a rare scleroderma mimicker Werner综合征或成人早衰症:一种罕见的模仿硬皮病的疾病
IF 0.4 Q4 DERMATOLOGY Pub Date : 2023-01-01 DOI: 10.4103/ejdv.ejdv_12_22
Jasleen Sandhu, Ankita Tuknayat
Werner syndrome, a premature aging disorder, is a rare cause of pseudoscleroderma and can present with a multitude of clinical features involving the skin, endocrine and cardiovascular systems. Although genetic, the disease has its onset in puberty and cutaneous features like graying of hair, atrophic sclerotic skin, recurrent ulcers, and dyspigmentation are the first to manifest. All these features usually mislead the clinician to make a diagnosis of systemic sclerosis. A similar case is being presented and the importance of differentiating these two disorders is being discussed.
沃纳综合征是一种早衰性疾病,是一种罕见的假性硬皮病的病因,可表现出多种临床特征,涉及皮肤、内分泌和心血管系统。虽然这种疾病是遗传性的,但它在青春期发病,皮肤特征如头发变白、皮肤萎缩硬化、复发性溃疡和色素沉着是首先表现出来的。所有这些特征通常会误导临床医生做出系统性硬化症的诊断。有人提出了一个类似的病例,并讨论了区分这两种疾病的重要性。
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引用次数: 0
Alterations of thyroid functions in patients with nonsegmental vitiligo: a cross-sectional study 非节段性白癜风患者甲状腺功能改变:一项横断面研究
IF 0.4 Q4 DERMATOLOGY Pub Date : 2023-01-01 DOI: 10.4103/ejdv.ejdv_22_22
W. Abd-Elmagid, Dalia Hagag, S. Sayed, Sahar Aboelfetoh, R. Saleh
Background Autoimmunity is the most commonly accepted theory in the pathogenesis of vitiligo. This is supported by the association of vitiligo with many other autoimmune diseases, such as Hashimoto thyroiditis and Graves’ disease. Aim The aim of this study was to investigate the laboratory profiles of a cohort of patients with nonsegmental vitiligo (NSV). Patients and methods This cross-sectional study included 100 patients with NSV and 100 age-matched and sex-matched healthy volunteers as controls. Laboratory workup included thyroid-stimulating hormone, triiodothyronine, thyroxine, free thyroxine, antithyroid peroxidase antibody, antithyroglobulin antibody, and antinuclear antibody (ANA). Results Thyroid-stimulating hormone, triiodothyronine, and thyroxine showed a significant difference between patients with vitiligo and control (P=0.007). There was a statistically significant increase in the level of antithyroid peroxidase antibody (P=0.000) and antithyroglobulin antibody (P=0.000) antibodies in patients with NSV. Conclusion NSV is associated with disturbance of thyroid function tests and significant increase of thyroid autoantibodies.
背景自身免疫是白癜风发病机制中最普遍接受的理论。白癜风与许多其他自身免疫性疾病(如桥本甲状腺炎和格雷夫斯病)的关联支持了这一点。目的本研究的目的是调查非节段性白癜风(NSV)患者队列的实验室资料。患者和方法本横断面研究包括100名NSV患者和100名年龄和性别匹配的健康志愿者作为对照。实验室检查包括促甲状腺激素、三碘甲状腺原氨酸、甲状腺素、游离甲状腺素、抗甲状腺过氧化物酶抗体、抗甲状腺球蛋白抗体、抗核抗体(ANA)。结果白癜风患者促甲状腺激素、三碘甲状腺原氨酸、甲状腺素水平与对照组比较差异有统计学意义(P=0.007)。非NSV患者抗甲状腺过氧化物酶抗体(P=0.000)和抗甲状腺球蛋白抗体(P=0.000)水平升高有统计学意义。结论非NSV与甲状腺功能测试紊乱及甲状腺自身抗体显著升高有关。
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引用次数: 0
Histopathologic profile of cutaneous cystic lesions in teaching hospital, Nnewi, South-east, Nigeria: a 9-year Review 尼日利亚东南部Nnewi教学医院皮肤囊性病变的组织病理学分析:9年回顾
IF 0.4 Q4 DERMATOLOGY Pub Date : 2023-01-01 DOI: 10.4103/ejdv.ejdv_34_22
I. Ezejiofor, Olaniyi Olaofe, O. Ezejiofor, C. Ukah, N. Ozor, AdeizaS Enesi, ChukwuemekaN Osonwa
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引用次数: 0
Systemic comorbidities in patients of psoriasis: a case–control study from India 银屑病患者的全身合并症:一项来自印度的病例对照研究
IF 0.4 Q4 DERMATOLOGY Pub Date : 2023-01-01 DOI: 10.4103/ejdv.ejdv_15_22
S. Chavhan, Sugat A Jawade, Bhushan Madke, A. Singh
Background There is paucity of Indian studies on comprehensive assessment of systemic comorbidities in psoriasis. This study aimed at assessing the systemic comorbidities in patients of psoriasis in India. Patients and methods A case–control study was conducted from September 2019 to August 2021. Study participants of more than 18 years, with 30 psoriasis patients as cases and 30 healthy individuals as controls. Assessment of Psoriasis Area Severity Index in cases, BMI, waist circumference, blood pressure, and detailed systemic index evaluation was done in both the groups. Analyses were done using χ2 test and independent t test. Analysis of variance test is used to compare continuous variables among more than two groups. Odds ratio (OR) and 95% confidence interval were calculated. Results The mean age of psoriasis cases was 45.03±13.1 years with 73.3% of male and 26.7% of female population. Mean duration of psoriasis observed is 6.9±4.2 years with the mean Psoriasis Area Severity Index of 17.73±6.389. Comparison of systemic indices demonstrated significant increase in neutrophil count (P=0.006), erythrocyte-sedimentation rate (P<0.0001), glycated hemoglobin (P=0.037), low-density lipoprotein (P=0.0418), T3 (P<0.0001), and T4 (P=0.018). No significant difference in the liver-function test and renal-function test was seen in both the groups. Comparison of the prevalence of diseases associated with psoriasis, shows that the prevalence of metabolic syndrome (60 vs. 30%, OR=3.5, P=0.021), nonalcoholic fatty liver disease (26.6 vs. 6.6%, P=0.002, OR=14), increase in the carotid artery intimal thickness on both sides (right P=0.007, OR=5; left P=0.005, OR=7), and the inflammatory marker C-reactive protein (70 vs. 33.3%, P=0.005, OR=4.66) is significantly increased in cases as compared with controls. Other diseases like obesity (BMI: OR=2.0417, P=0.187; waist circumference: OR=2.25, P=0.123), type-2 diabetes mellitus (P=0.56, OR=1.40), hypertension (P=0.78, OR=1.15), and renal disease (P=1, OR=1) is found to have greater risk in psoriasis patients than controls, but the reflecting difference is not statistically significant. Conclusion The study revealed that the patients of psoriasis are more likely to have systemic comorbidities as compared with patients without psoriasis.
背景印度缺乏对牛皮癣系统性合并症的综合评估研究。本研究旨在评估印度银屑病患者的全身合并症。患者与方法2019年9月至2021年8月进行病例对照研究。研究对象超过18岁,其中30名牛皮癣患者作为病例,30名健康个体作为对照。对两组患者进行牛皮癣区域严重程度指数评估、BMI、腰围、血压及详细的全身指标评估。采用χ2检验和独立t检验进行分析。方差分析检验用于两组以上连续变量的比较。计算优势比(OR)和95%置信区间。结果银屑病患者平均年龄为45.03±13.1岁,男性占73.3%,女性占26.7%。平均病程为6.9±4.2年,平均银屑病区严重指数为17.73±6.389。全身指标比较显示,中性粒细胞计数(P=0.006)、红细胞沉降率(P<0.0001)、糖化血红蛋白(P=0.037)、低密度脂蛋白(P=0.0418)、T3 (P<0.0001)、T4 (P=0.018)显著升高。两组肝功能、肾功能检查无明显差异。比较银屑病相关疾病的患病率,发现代谢综合征(60比30%,OR=3.5, P=0.021)、非酒精性脂肪性肝病(26.6比6.6%,P=0.002, OR=14)、两侧颈动脉内膜厚度增加(右侧P=0.007, OR=5;左P=0.005, OR=7),炎症标志物c反应蛋白(70比33.3%,P=0.005, OR=4.66)与对照组相比显著升高。其他疾病如肥胖(BMI: OR=2.0417, P=0.187;银屑病患者腰围:OR=2.25, P=0.123)、2型糖尿病(P=0.56, OR=1.40)、高血压(P=0.78, OR=1.15)、肾脏疾病(P=1, OR=1)的风险高于对照组,但反映差异无统计学意义。结论银屑病患者与非银屑病患者相比,更易出现全身合并症。
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引用次数: 0
期刊
Egyptian Journal of Dermatology and Venereology
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