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Histopathological and immunohistochemical studies on the effects of Ethephon on liver and kidney in male rats 乙烯利对雄性大鼠肝、肾影响的组织病理学和免疫组化研究
Pub Date : 1900-01-01 DOI: 10.21608/jmals.2019.179684
E. Tousson, Afaf M. El-Atrsh, Merfaat Mansour, A. Assem
Ethephon can release ethylene which could affect the plant growth process. The current study was designed to study the possible toxic effects of ethephon on both liver and kidneys of male rats. 20 adult male rats were divided into 2 groups; the first group is control and the second group received Ethephon at dose (200 mg/kg body weight/day) for four weeks. At the end of the study liver and kidney tissues were taken and examined histopathologically. Ethephon administration to rats showed marked injury in liver and kidney. Also, liver and kidney sections in treated rats with Ethephon showed strong positive affinity for PCNA expressions. These results indicated that Ethephon could be harmful on liver and kidney. Producers and consumers should become more aware about the toxic effects of Ethephon.
乙烯利会释放乙烯,影响植物的生长过程。本研究旨在研究乙烯利对雄性大鼠肝脏和肾脏可能产生的毒性作用。20只成年雄性大鼠分为2组;第一组为对照组,第二组给予乙醚利(200 mg/kg体重/天)治疗,疗程4周。在研究结束时,取肝脏和肾脏组织进行组织病理学检查。乙烯利对大鼠肝、肾有明显损伤。此外,乙烯利处理大鼠的肝脏和肾脏切片对PCNA的表达有很强的正亲和性。提示乙烯利对肝脏和肾脏有一定的危害。生产者和消费者应该更加意识到乙烯利的毒性作用。
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引用次数: 5
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Journal of Medical and Life Science
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