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Prevalence of non-adherence to medications in people with type 2 Diabetes mellitus 2型糖尿病患者不遵医嘱的患病率
IF 0.6 Pub Date : 2023-01-01 DOI: 10.5455/jcmr.2023.14.01.21
F. Alfhaid, Mansour Alzahrani, H. Alzahrani, M. Aljulifi, A. Alqabbani, N. Alzaidy, A. Almutairi, S. Alsaadoon
Diabetes mellitus (DM) is a chronic, non-communicable disease that has an increasing incidence rate over time as well as increasing disease-related deaths. Furthermore, around half of diabetic patients are unaware actually about their disease, and more are not taking their medications. This study aimed to determine the extent of medication adherence and factors contributing to non-adherence among diabetic patients in Majmaah governance, Saudi Arabia. This is an observational cross-sectional study design conducted among patients with type 2 diabetes. A self- administered questionnaire was distributed among diabetic patients .The questionnaire consisted of socio- demographic data, HbA1c level, duration of DM, family history of DM, DM medications and 12-Item Medication Adherence Scale. 180 patients with diabetes type 2 were involved (71.7% females vs. 28.3% males). The prevalence of patients with uncontrolled HbA1c levels was 25%. Family history of DM constitutes 74.4%. The most preferred route for drug administration was oral (50.6%). High non-adherent to medication was found among 57.8%. The independent significant factor associated with high non-adherence to DM medication was uncontrolled HbA1c while being a female was the independent significant factor for low non-adherent to DM medication. The non-adherent of the diabetic patients regarding anti-diabetes medications was widely prevalent. Female patients tend to be more adherent to DM medication than their male counterparts. This study established the fact that uncontrolled glycated hemoglobin was a detrimental factor in adherence to anti-DM medications. More studies are required to raise the awareness of the diabetic population regarding the importance of medication adherence.
糖尿病(DM)是一种慢性非传染性疾病,随着时间的推移,发病率不断上升,与疾病相关的死亡人数也在增加。此外,大约一半的糖尿病患者实际上并不知道自己的疾病,更多人没有服用药物。本研究旨在确定沙特阿拉伯Majmaah治理的糖尿病患者的药物依从性程度和导致不依从性的因素。这是一项在2型糖尿病患者中进行的观察性横断面研究设计。对糖尿病患者进行问卷调查,问卷内容包括社会人口学资料、糖化血红蛋白水平、糖尿病病程、糖尿病家族史、糖尿病用药情况和12项药物依从性量表,共纳入180例2型糖尿病患者(女性71.7%,男性28.3%)。HbA1c水平不受控制的患者患病率为25%。糖尿病家族史占74.4%。给药方式以口服为主(50.6%)。药物高度不依从性占57.8%。与糖尿病药物高不依从性相关的独立显著因素是未控制的HbA1c,而女性是糖尿病药物低不依从性的独立显著因素。糖尿病患者抗糖尿病药物不依从性普遍存在。女性患者往往比男性患者更坚持右美沙芬药物治疗。本研究确定了一个事实,即不受控制的糖化血红蛋白是坚持抗糖尿病药物的一个有害因素。需要更多的研究来提高糖尿病患者对药物依从性重要性的认识。
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引用次数: 0
The Nematicidal Activity of Moringa Oleifera Leaves Extract Against Gastro-Intestinal Strongyles of Small Goats 辣木叶提取物对小山羊胃肠道圆形细胞的杀线虫活性研究
IF 0.6 Pub Date : 2023-01-01 DOI: 10.5455/jcmr.2023.14.01.30
M. Gertrude, Yondo Jeannette, T. Gabriel, N. Stephanie, M. Mbida
Introduction: Gastrointestinal nematodes have a deleterious effect on animal health and production. In search of alternative to synthetic anthelminthics in the control of strongylosis among small ruminants, this study was conducted to evaluate the in situ adulticidal properties of Moringa oleifera on gastro-intestinal strongyles of goats. Methods: Twenty (20) goats naturally infested with mixed gastrointestinal nematodes were distributed into 5 groups (n=4): a negative control group receiving Tween 80 at 2.8%, a positive control group treated with Albendazole at 5 mg/kg and tested groups treated with doses of extract (125, 250 and 500 mg/kg). In situ anthelminthic activity was assessed through determination of the faecal eggs count reduction, total worm count reduction, variation of packed cell volume (PCV) and body weight after treatment. Results: Five species of nematodes were identified among experimental animals, with Strongyloides papillorus as the most prevalent (93.8%) followed by Haemonchus contortus (87.5%). At dose of 500 mg/kg, ethanolic extract of M. oleifera registered 76.4 % and 69.8 % eggs density reduction of gastro-intestinal strongyles eggs and parasitic load nineteen days post-treatment respectively while Albendazole induced 100 % reduction of these same parameters at the dose of 5 mg/kg. Moreover, the extract did not significantly affect PCV nor body weight of experimental goats. Conclusion: This study validates scientifically the use of alcoholic leaves extract of M. oleifera in the treatment of gastro-intestinal strongyles. The standardization of this extract is however necessary for his use as a sustainable tool for controlling strongylosis in small ruminants.
胃肠道线虫对动物健康和生产有严重的危害。为了寻找替代人工合成灭虫剂防治小反刍动物圆线虫病的方法,本试验研究了辣木对山羊胃肠道圆线虫的原位杀虫效果。方法:将自然感染混合胃肠道线虫的山羊20只分为5组(n=4):阴性对照组以2.8%剂量的Tween 80治疗,阳性对照组以5 mg/kg剂量的阿苯达唑治疗,试验组以125、250和500 mg/kg剂量的提取物治疗。通过测定处理后的粪卵减少量、总虫数减少量、堆积细胞体积(PCV)和体重的变化来评估原位驱虫活性。结果:实验动物共检出线虫5种,其中以乳头状圆线虫最多(93.8%),其次是弯曲血蜱(87.5%);在500 mg/kg剂量下,油桐醇提物处理19 d后,胃肠道圆形细胞卵密度和寄生负荷分别降低76.4%和69.8%,而在5 mg/kg剂量下,阿苯达唑可使上述参数降低100%。此外,该提取物对试验山羊的PCV和体重均无显著影响。结论:科学地验证了油松叶醇提物对胃肠道圆形细胞的治疗作用。然而,这种提取物的标准化是必要的,以便将其用作控制小反刍动物中圆形菌病的可持续工具。
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引用次数: 0
Investigation of The Relationship between The Pesticide Fluopyram and Parkinson’s disease 农药氟吡嗪与帕金森病关系的研究
IF 0.6 Pub Date : 2023-01-01 DOI: 10.5455/jcmr.2023.14.01.01
Hanan Sammarraie, Nurten elik, Dilek elik, G. rel, brahim Onaran, No author No author, P. Ar, Meltem men
Parkinson's disease (PD) is a neurodegenerative disease defined as a shaky stroke. It is clinically characterized by; resting tremor, cogwheel rigidity, bradykinesia, and postural reflex impairment. It is also pathologically characterized by Lewy bodies (LBs) and formed by the loss of dopaminergic neurons in the Substantia nigra pars compacta (SNpc) region of the brain and the accumulation of AlphaSynuclein (α-Syn) proteins. Pesticides are the hugest risk factor of PD. They cause the formation of PD by using different mechanisms. They also permanently disrupt the function of the electron transport complex (ETC) located in the mitochondria. Researches show that the pesticide Rotenone (ROT) causes PD in vivo and in vitro conditions by inhibiting mitochondrial complex I and causing oxidative stress. Fluopyram (Flu) is a frequently used pesticide that causes mitochondrial toxicity like ROT. When literature is searched, it makes one think about a connection with PD. it seems that there is no available study on Flu and PD. Flu is one of the fungicides utilized in Isparta city at a high rate for all planting types. The Flu is a mitochondrial complex II inhibitor. The inhibition of mitochondrial complexes is the main pathway in the PD mechanism, therefore complex II inhibitor pesticide may lead to the same result. In this context, we created a Parkinson's model in mice with ROT and compare the result of Flu with this ROT to be sure whether that lead to Parkinson's or not. Swiss albino male and female mice were the testing animals of our study. Positive control (ROT Parkinson model, 1 mg/kg/day), negative control (Solvent only, DMSO), and Flu (0.5,1 and 2 mg/kg/day) were administrated to mice daily doses subcutaneously (SC). The experiment got completed after 21 days. Motor Function Test, Histochemical and Immunohistochemical Studies, Comet assay, and quantitative real-time PCR (qRT-PCR) were utilized in the study as well. In our results, no statistically significant changes were observable in animal weights in all groups. In the motor function test, a significant decrease in the ROT group was observable, On the other hand, a significant decrease was detected specifically in the Flu value which was applied at high doses. When the brain tissues that belong to the ROT and Flu tested groups got examined, all-important structural changes such as LBs got observed in the SN. When brain tissues belonging to ROT and Flu groups were examined in α-Syn immunohistochemical staining, more positive markings were observable. When the brain tissues belonging to the ROT and Flu groups were examined in Tyrosine hydroxylase (TH) immunohistochemical staining, fewer positive markings were observed. ROT has been found to cause DNA damage in blood and brain tissues. It has been determined that groups with Flu applied in the brain do not have DNA damage. ROT was observed to increase SNCA mRNA expression levels while decreasing TH and DJ-1 mRNA expression levels. Comparing the Fl
帕金森病(PD)是一种神经退行性疾病,被定义为震颤性中风。临床表现为:静息性震颤、齿轮强直、运动迟缓和姿势反射障碍。它也以路易体(Lewy bodies, LBs)为病理特征,由大脑黑质致密部(SNpc)区域多巴胺能神经元的丧失和α-Syn蛋白的积累而形成。农药是帕金森病最大的危险因素。它们通过不同的机制导致PD的形成。它们还永久性地破坏位于线粒体中的电子传递复合物(ETC)的功能。研究表明,农药鱼藤酮(Rotenone, ROT)通过抑制线粒体复合体I和引起氧化应激,在体内和体外条件下引起PD。氟吡喃(Flu)是一种常用的杀虫剂,会导致线粒体毒性,如ROT。当搜索文献时,它会让人想到与帕金森病有关。似乎没有关于流感和帕金森病的研究。流感是isparta市所有种植类型中使用率很高的杀菌剂之一。流感病毒是一种线粒体复合体II抑制剂。线粒体复合物的抑制是PD机制的主要途径,因此复合物II抑制剂农药可能导致相同的结果。在这种情况下,我们在患有ROT的小鼠中创建了帕金森病模型,并将流感的结果与这种ROT进行比较,以确定是否会导致帕金森病。本研究以瑞士白化雄性和雌性小鼠为实验动物。阳性对照(ROT帕金森模型,1mg/kg/天)、阴性对照(仅溶剂、DMSO)和Flu(0.5、1和2mg /kg/天)每日皮下给药(SC)。21天后完成实验。运动功能测试、组织化学和免疫组织化学研究、Comet测定和实时荧光定量PCR (qRT-PCR)也被用于研究。在我们的研究结果中,各组动物体重没有明显的统计学变化。在运动功能测试中,ROT组明显下降,另一方面,在高剂量应用时,流感值明显下降。当对ROT和Flu测试组的脑组织进行检查时,在SN中观察到所有重要的结构变化,如LBs。对ROT组和Flu组脑组织进行α-Syn免疫组化染色,可见阳性标记较多。当对ROT组和Flu组脑组织进行酪氨酸羟化酶(TH)免疫组化染色时,阳性标记较少。ROT已被发现会导致血液和脑组织中的DNA损伤。已经确定,在大脑中注射流感疫苗的人群没有DNA损伤。ROT升高了esnca mRNA的表达水平,降低了TH和DJ-1 mRNA的表达水平。比较流感和ROT结果,SNCA mrna表达水平升高,但不显著。随着TH和DJ-1 mRNA表达水平的降低,我们的ROT结果显示了这种差异。总之,本研究结果证明了流感对小鼠PD表型的诱导依赖于流感剂量。建议对流感做更多的研究,特别是在高剂量和不同的方法下
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引用次数: 0
Global Challenges of Modern Era: Cardiovascular Diseases at The Beginning of XXI Century 现代的全球挑战:21世纪初的心血管疾病
IF 0.6 Pub Date : 2023-01-01 DOI: 10.5455/jcmr.2023.14.03.01
E. Korableva, T. Bocharova, Lidia Sklyar, V. Shakolyukova
At the beginning of XXI century cardiovascular diseases continue to be the most significant problem for modern medicine as the field of theoretical scientific knowledge, practical medicine, social, economic and domestic political spheres of activity in most countries of the world, and against the background of the outbreak of modern pandemics they have taken on the outlines of serious challenges to humanity, its viability. Particular attention is drawn to the fact that the population of the whole world feels the consequences of cardiovascular diseases expressed in the steady disability of the adult population, demographic decline, low life expectancy and high mortality rates. As analyzed in the article, these facts have become a serious basis for finding the ways to combat cardiovascular diseases on a global scale coordinating the actions and efforts of different countries in a single common task. In the work the author focuses the main attention on how important it is to convey the message to the international community that the problem of cardiovascular diseases is not only a strictly medical one and that it is beyond the power of healthcare organizations to solve it alone, even having mobilized all their capabilities. The purpose of the research:To create a general picture of cardiovascular pathology in the modern world as a global social problem in order to find ways to correct the activities of national and international health organizations, as well as non-medical organizations to combat heart pathologies.
21世纪初,心血管疾病作为世界大多数国家的理论科学知识、实践医学、社会、经济和国内政治活动领域,仍然是现代医学面临的最重大问题,在现代大流行病爆发的背景下,心血管疾病对人类及其生存能力构成了严重挑战。特别提请注意的是,全世界人民都感受到心血管疾病的后果,表现在成年人口持续残疾、人口减少、预期寿命低和死亡率高。正如文章所分析的那样,这些事实已成为在全球范围内寻找防治心血管疾病的方法的重要基础,协调不同国家在单一共同任务中的行动和努力。在工作中,作者将主要注意力集中在向国际社会传达这样一个信息是多么重要:心血管疾病问题不仅是一个严格的医学问题,而且即使动员了所有能力,医疗机构也无法单独解决这一问题。研究的目的是:建立现代世界心血管病理学作为一个全球性社会问题的总体情况,以便找到纠正国家和国际卫生组织以及非医疗组织与心脏病作斗争的活动的方法。
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引用次数: 0
Prevalence of Refractive Errors Among Saudi Population: A Systematic Review and Meta-Analysis 沙特人口屈光不正患病率:系统回顾和荟萃分析
IF 0.6 Pub Date : 2023-01-01 DOI: 10.5455/jcmr.2023.14.03.04
Majid Moafa
Background: Refractive errors are common globally with an estimated number of 2.3 billion people suffering from impaired vision secondary to uncorrected refractive errors. This study aimed to estimate a piece of proper evidence about the overall prevalenceof refractory errors within the kingdom. Methods: A process of collection of relevant key words was conducted followed by database search. All data were analyzed with R software version 4.0.2. Using a “meta” package. The event rate and the corresponding 95% confidence interval (CI) was used to assess the prevalence of refractive errors in the study. Results: The sample size was 16850 individual with the highest sample size was 5176 and the lowest one was 162. The male prevalence in our sample was 55%. All the included papers were published after 2010 and were of fair quality. Eleven studies of 12,121 individuals reported the overall prevalence of different refrative erros. The pooled overall prevalnce rate was 27.28% (95% CI= 18.29-40.69) (Figure 2A); ranging from 4.55% to 72.20% among individual studies. This wide range of the reported prevalence rates was evident with a significant heterogenity among the included studies (I2= 99%; P-value< 0.001). Conclusion: A huge part of the high rates might be attributable to medical students. Moreover, myopia was the most common refractive error followed by astigmatism and hyperopia.
背景:屈光不正在全球很常见,估计有23亿人因未矫正的屈光不正而继发视力受损。这项研究的目的是估计一个适当的证据,在王国的顽固性错误的总体患病率。方法:先收集相关关键词,然后进行数据库检索。所有数据采用R软件4.0.2版进行分析。使用“meta”包。使用事件率和相应的95%置信区间(CI)来评估研究中屈光不正的发生率。结果:样本量为16850人,最大样本量为5176人,最小样本量为162人。我们样本中的男性患病率为55%。收录的论文均为2010年以后发表的论文,质量一般。11项涉及12121人的研究报告了不同屈光不正的总体患病率。合并总患病率为27.28% (95% CI= 18.29-40.69)(图2A);在个别研究中从4.55%到72.20%不等。报告的患病率范围如此之广,在纳入的研究中存在显著的异质性(I2= 99%;假定值< 0.001)。结论:医学生可能是造成高发生率的主要原因。此外,近视是最常见的屈光不正,其次是散光和远视。
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引用次数: 0
Polyphenols as bioactive food components in relation to autism spectrum disorders: An overview of the literature 多酚作为与自闭症谱系障碍相关的生物活性食物成分:文献综述
IF 0.6 Pub Date : 2023-01-01 DOI: 10.5455/jcmr.2023.14.03.30
B. Alahmadi
Autism spectrum disorder (ASD) known as a set of behavioral and neurocognitive problems that are identified by challenges in difficulties interacting and communicating with others, as well as heightened repetitive and/or restrictive behaviors. Elevated immune reaction and enhancements in pro-inflammatory cytokines have been discovered in the brains of those who have ASD. A recent article associated autism with abnormalities in mitochondrial respiratory control. Based on various studies, mitochondrial dysfunction is caused by oxidative stress, inadequate nutrition, insufficiency of vitamins, compromised immune system, contact with harmful environmental substances, and modified calcium signaling. Polyphenols found in our diet are active compounds that have the potential to prevent and treat various chronic illnesses including, neurodegenerative and neurodevelopmental problems. This is mainly due to their ability to regulate crucial pathways that cause inflammation and oxidation in the body. The application of polyphenols may result in a reduction of neuroinflammation, facilitating an improvement in the manifestations of ASD. This review focused on the preclinical and clinical studies that documented the beneficial impacts of diet related for the modulation of ASD.
自闭症谱系障碍(ASD)被称为一系列行为和神经认知问题,其特征是与他人互动和沟通困难,以及重复性和/或限制性行为加剧。在自闭症谱系障碍患者的大脑中发现了免疫反应升高和促炎细胞因子增强。最近的一篇文章将自闭症与线粒体呼吸控制异常联系起来。根据各种研究,线粒体功能障碍是由氧化应激、营养不足、维生素不足、免疫系统受损、接触有害环境物质和钙信号改变引起的。在我们的饮食中发现的多酚是一种活性化合物,具有预防和治疗各种慢性疾病的潜力,包括神经退行性疾病和神经发育问题。这主要是由于它们有能力调节导致体内炎症和氧化的关键途径。多酚类药物的应用可能会减少神经炎症,促进ASD表现的改善。这篇综述的重点是临床前和临床研究,这些研究记录了饮食对ASD调节的有益影响。
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引用次数: 0
Managing Stress Of Nurses Through Their Efficiencies And Commitment: An Empirical Investigation 通过护士的效率和承诺管理压力:一项实证调查
IF 0.6 Pub Date : 2023-01-01 DOI: 10.5455/jcmr.2023.14.03.07
S. Alflayyeh, Maha Almujalli
It has been determined that nursing is a profession with high levels of stress. Not only did nurses' health suffer because of the stress of their jobs, but they also struggled to cope with the demands of their jobs. This study aimed to figuring out how to manage nursing shifts to avoid Work-related Stress and haw to control and manage nursing works to avoids work-related stress in nursing, which can affect it. according to some independent variables such as the type of nurse, the scientific qualification, the type of hospital, the social situation, and the age group. The researchers selected a sample of (168) nurses who work in private clinics. Collected data was analyzed through SPSS version 22. Findings shows that all the considered constructs are having a strong relationship.
人们已经确定,护理是一个压力很大的职业。护士的健康不仅因为工作压力而受到影响,而且他们也在努力应对工作的要求。本研究旨在探讨如何管理护理班次以避免工作压力,以及如何控制和管理护理工作,以避免护理工作压力对工作压力的影响。根据一些自变量,如护士类型、科学资格、医院类型、社会情况和年龄组。研究人员选取了168名在私人诊所工作的护士作为样本。收集的数据通过SPSS version 22进行分析。研究结果表明,所有被考虑的构念都有很强的关系。
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引用次数: 0
Impact of COVID-19 on Smoking Behaviour Majmaah University, Saudi Arabia 新冠肺炎对吸烟行为的影响沙特阿拉伯Majmaah大学
IF 0.6 Pub Date : 2023-01-01 DOI: 10.5455/jcmr.2023.14.01.09
R. Alzahrani, Bandar Alsaadoon, Abdulaziz Almasaudi, Murad Almutairi, Majeed Alanazi, Mohamad Alolah
The main aim of this study was to evaluate the impact of Covid-19 pandemic on the smoking behavior among the people of Majmaah University. This Cross sectional study was conducted in Majmaah city from September 2020 to June 2020. It was an observational study and a total of 180 people were included in this. The inclusive criteria of this study was smoker male and female population. Online questionnaire was used to collect data. Out of total 180, 91 % population comprised of men and females were 8.9 %. The results of this study stated that 88.9 % people were active smokers. Cigarette was the most common form of tobacco consumption, 71.1 %. During the Covid-19 pandemic, almost 40 % of the participants decreased smoking and 35.6 % increased smoking. While after the pandemic ended 35.6 % of the participants increased smoking and 26.1 % decreased. There was a significant association between the current use of tobacco/nicotine and gender, with p value being less than 0.05. There was also significant association between knowledge of severely affect the lung and respiratory system and gender, with p value being less than 0.05. This study concluded that the Covid-19 pandemic lockdown affected the smoking behavior of many people in Saudi Arabia. Majority of people decreased smoking during the pandemic. On the other hand, majority of the people increased smoking after the pandemic ended. The results of this study indicated the need of awareness among the people regarding smoking and its side effects so that healthy living could be promoted among the masses. This would eventually lead to a healthy society and boost in immunity of the people in such a way that health related crisis could be easily fought in the future. Covid-19 provided a good opportunity for people to quit smoking.
本研究的主要目的是评估新冠肺炎大流行对Majmaah大学人群吸烟行为的影响。该横断面研究于2020年9月至2020年6月在Majmaah市进行。这是一项观察性研究,共有180人参与其中。本研究的纳入标准为吸烟男性和女性人群。采用在线问卷收集数据。其中,男性占总人口的91%,女性占8.9%。这项研究的结果表明,88.9%的人是活跃吸烟者。香烟是最常见的烟草消费形式,占71.1%。在Covid-19大流行期间,近40%的参与者减少了吸烟,35.6%的参与者增加了吸烟。而在大流行结束后,35.6%的参与者增加了吸烟,26.1%的参与者减少了吸烟。当前烟草/尼古丁使用情况与性别之间存在显著相关性,p值小于0.05。对严重影响肺呼吸系统的认知程度与性别也有显著相关,p值均小于0.05。这项研究得出的结论是,新冠肺炎大流行的封锁影响了沙特阿拉伯许多人的吸烟行为。在大流行期间,大多数人减少了吸烟。另一方面,大流行结束后,大多数人的吸烟量增加了。这项研究的结果表明,有必要提高人们对吸烟及其副作用的认识,以便在群众中促进健康生活。这将最终导致一个健康的社会,提高人们的免疫力,从而使未来与健康相关的危机可以轻松地进行斗争。新冠肺炎疫情为人们戒烟提供了一个很好的机会。
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引用次数: 0
Prevalence and Management of Post-Extraction Complications 拔牙后并发症的发生率及处理
IF 0.6 Pub Date : 2023-01-01 DOI: 10.5455/jcmr.2023.14.02.14
M. Assiry, Mohammed M. Aloqbi, H. Albrahim, Abdulaziz K. Alnabulsi, Hala Alim, Maisa Ghamdi, Lojain Bassyoni
Introduction: Simple tooth extraction is one of the most common procedures performed by general dentists and Oral and Maxillofacial surgeons throughout daily practice. However, although it is a simple procedure, tooth-related complications could occur at any time. These complications are categorized into immediate and delayed complications. Immediate complications are due to either tooth-related or dentist-related factors and require prompt actions and immediate management. Tooth-related factors depend on tooth morphology and tooth structure conditions. Dentist-related factors depend on the proper selection and application of the instruments. On the other hand, delayed complications might occur after two days or more following the extraction. Objective: To evaluate the prevalence, prediction of risk factors complications, prevention and management of possible immediate and delayed post-extraction complications occurring in our Oral Surgery clinics at King Abdulaziz University Dental Hospital. Method: An observation and assessment of the extraction procedure, data collected via validated survey were used to gather the following: Demographic data, medical history, cause of extraction, number of tooth/teeth extracted, complications if any, and who did the procedure. For each patient who underwent dental extraction, a survey was filled out, by a doctor other than the operator and the procedure was assessed under observation to record any complications that occurred during the procedure and assess the undertaken management in such a case without intervention. Data was analyzed using Chi-square test through SPSS. Result: We observed 172 extraction procedures with 160 different patients, 12 had extraction more than once. A total 350 teeth were extracted from 160 patients, we observed 92 complications (53.4%) between immediate and delayed, 7 patients had both, the most common immediate complication was soft tissue injury with (81.7%) 67/82, and for the delayed complications the most common was dry socket (64.7%) 11/17 patients. Conclusion: In conclusion, we found a significant association between the number of post-operative complications, their management, and the experience of the operator
简介:简单的拔牙是普通牙医和口腔颌面外科医生在日常实践中最常见的程序之一。然而,虽然这是一个简单的过程,但与牙齿相关的并发症随时可能发生。这些并发症分为即时和延迟性并发症。即刻并发症是由于与牙齿或牙医有关的因素引起的,需要迅速采取行动和立即处理。与牙齿有关的因素取决于牙齿形态和牙齿结构状况。与牙科有关的因素取决于仪器的正确选择和应用。另一方面,延迟并发症可能发生在拔牙后两天或更长时间。目的:了解阿卜杜勒阿齐兹国王大学牙科医院口腔外科门诊拔牙后即刻及延迟并发症的发生率、危险因素预测及预防和处理。方法:对拔牙过程进行观察和评估,通过有效的调查收集以下数据:人口统计资料、病史、拔牙原因、拔牙数、是否有并发症、拔牙者。对于每位接受拔牙的患者,由除操作者以外的医生填写一份调查问卷,并在观察下评估手术过程,以记录手术过程中发生的任何并发症,并评估在没有干预的情况下所采取的管理措施。数据分析采用SPSS卡方检验。结果:对160例患者进行了172例拔牙,其中12例拔牙次数超过一次。160例患者共拔牙350颗,即刻和延迟并发症92例(53.4%),两者均有7例,即刻并发症以软组织损伤最常见(81.7%),占67/82,延迟并发症以干槽损伤最常见(64.7%),占11/17。结论:总之,我们发现术后并发症的数量及其处理与手术者的经验有显著的相关性
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引用次数: 0
Current Approaches to The Treatment of Chronic Diseases: Prospects for The Use of Innovative Methods and Technologies in Medicine 目前治疗慢性病的方法:在医学上使用创新方法和技术的前景
IF 0.6 Pub Date : 2023-01-01 DOI: 10.5455/jcmr.2023.14.03.10
Dmitry Zemel, Saida Saadulaeva, Ekaterina Chikisheva, N. Kashentseva, A. Boldyrev, Georgiy Aramyanc
This article examines current approaches to the treatment of chronic diseases and prospects for the use of innovative methods and technologies in medicine. The paper presents an overview of modern methods of treatment of chronic diseases, such as drug therapy, exercise, diet and lifestyle changes. New methods are also being considered, such as the use of technologies related to AI, biotechnology, gene therapy, nanotechnology, etc. In addition, the authors describe how these methods can help in more accurate diagnosis and the choice of individual treatment for the patient. The article also discusses the advantages and disadvantages of each method, as well as the potential risks and ethical issues associated with their use. The authors conclude that the use of innovative methods and technologies can significantly improve the effectiveness of treatment of chronic diseases and improve the quality of life of patients, but also requires additional research and regulation by medical organizations and governments. One of the most promising areas in the treatment of chronic diseases is the use of AI and machine learning. These technologies can help in more accurate diagnosis, selection of individual treatment, monitoring of the patient's condition and prediction of possible complications. Biotechnologies also provide new opportunities in the treatment of chronic diseases. For example, the use of therapeutic proteins and gene therapy can be effective in the treatment of certain forms of cancer, cystic fibrosis and other diseases. Nanotechnology may also have significant potential in the treatment of chronic diseases. Nanoparticles can be used to deliver drugs to specific places in the body and to diagnose early stages of diseases. However, it should be borne in mind that the use of innovative methods and technologies is also associated with risks and ethical issues. For example, when using gene therapy, unexpected side effects are possible, and the use of AI and machine learning can lead to problems with the confidentiality of patient data. In general, the use of innovative methods and technologies can significantly improve the effectiveness of treatment of chronic diseases and improve the quality of life of patients. However, before the introduction of these methods and technologies into medical practice, it is necessary to conduct thorough research, evaluate the effectiveness and safety, as well as take into account ethical and legal aspects
本文探讨了目前治疗慢性疾病的方法以及在医学中使用创新方法和技术的前景。本文概述了治疗慢性病的现代方法,如药物治疗、运动、饮食和生活方式的改变。新的方法也在考虑之中,例如使用与人工智能、生物技术、基因治疗、纳米技术等相关的技术。此外,作者还描述了这些方法如何帮助更准确的诊断和患者个体治疗的选择。文章还讨论了每种方法的优点和缺点,以及与它们的使用相关的潜在风险和伦理问题。作者的结论是,使用创新的方法和技术可以显著提高慢性疾病的治疗效果和改善患者的生活质量,但也需要医疗组织和政府进行更多的研究和监管。在慢性疾病治疗中最有前途的领域之一是使用人工智能和机器学习。这些技术可以帮助更准确的诊断,选择个体化治疗,监测患者的病情和预测可能的并发症。生物技术也为慢性疾病的治疗提供了新的机会。例如,使用治疗性蛋白质和基因疗法可以有效地治疗某些形式的癌症、囊性纤维化和其他疾病。纳米技术在治疗慢性疾病方面也可能具有巨大的潜力。纳米颗粒可用于将药物输送到身体的特定部位,并用于诊断疾病的早期阶段。但是,应当铭记的是,使用创新方法和技术也与风险和道德问题有关。例如,当使用基因治疗时,可能会出现意想不到的副作用,人工智能和机器学习的使用可能会导致患者数据的保密性问题。总的来说,采用创新的方法和技术可以显著提高慢性疾病的治疗效果,提高患者的生活质量。然而,在将这些方法和技术引入医疗实践之前,有必要进行彻底的研究,评估其有效性和安全性,并考虑到伦理和法律方面的问题
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Journal of Complementary Medicine Research
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