Pub Date : 2023-01-01DOI: 10.5455/jcmr.2023.14.02.34
Khiadi Ozaeva, A. Diasamidze, Roman Zamiatin, Tikhon Makarchuk, A. Asrorov, Marat Ageev
The article examines the features of ensuring the interaction of medical specialists and geriatric patients in modern conditions. According to the author, the interaction between doctors and geriatric patients is an important aspect of elderly care. This helps to ensure a better quality of life, reduce the risks of developing diseases and improve treatment outcomes. Doctors should take into account the unique needs of geriatric patients and work closely with specialists from other fields to ensure the best outcome for each patient.
{"title":"Ensuring The Interaction of Medical Specialists and Geriatric Patients in Modern Conditions","authors":"Khiadi Ozaeva, A. Diasamidze, Roman Zamiatin, Tikhon Makarchuk, A. Asrorov, Marat Ageev","doi":"10.5455/jcmr.2023.14.02.34","DOIUrl":"https://doi.org/10.5455/jcmr.2023.14.02.34","url":null,"abstract":"The article examines the features of ensuring the interaction of medical specialists and geriatric patients in modern conditions. According to the author, the interaction between doctors and geriatric patients is an important aspect of elderly care. This helps to ensure a better quality of life, reduce the risks of developing diseases and improve treatment outcomes. Doctors should take into account the unique needs of geriatric patients and work closely with specialists from other fields to ensure the best outcome for each patient.","PeriodicalId":41505,"journal":{"name":"Journal of Complementary Medicine Research","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72709226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.5455/jcmr.2023.14.01.10
Ahmed Almutairi, M. Ahmad, A. Alzahrani, Amirah Almutairi, Batool Almutair, Raghad Alghannam, W. Alghuyaythat
To evaluate the knowledge, awareness, and attitude (myths) of the general population about the first aid management of epistaxis. This cross-sectional study was conducted via an online questionnaire from March to August 2022. We generated google forms for data collection. The link to this google form was randomly shared on WhatsApp and Facebook platforms. A previously used questionnaire was used and tested in the pilot study over a sample of 20 participants. The questionnaire contained socio-demographic information including sex, age, occupation, and residence. Furthermore, the level of awareness was measured on behalf of epistaxis causes and actions which were further subdivided into many categories. Myths were also observed through a questionnaire For this cross-sectional study 407 participants aged 15 to 55 years were recruited. A total of 325 participants encountered epistaxis once in their lifetime. The 30% participants of in our study reported spontaneous epistaxis while 4.4% and 4.9% encountered it due to nasal trauma and fingernail trauma. In 7.6% of participants, epistaxis occurred due to bleeding disorders while 23% reported hypertension as the major reason. We observed that 94% population was familiar with the proper position that epistaxis patients required to control bleeding. Sitting with the head tilted forward as a coping mechanism was used in 48.9% of participants with 199 individuals practicing this while sitting with the head tilted backward was practiced by 117 (28.7%) participants. The general population had enough knowledge to manage epistaxis. The awareness levels of the population show a positive reflection of the healthcare system. However, we recommend that further studies should be conducted with a large sample size to evaluate the validity of our research.
{"title":"First Aid Management and Myths of Epistaxis among General Adult Saudi population of Al Majmaah, Saudi Arabia","authors":"Ahmed Almutairi, M. Ahmad, A. Alzahrani, Amirah Almutairi, Batool Almutair, Raghad Alghannam, W. Alghuyaythat","doi":"10.5455/jcmr.2023.14.01.10","DOIUrl":"https://doi.org/10.5455/jcmr.2023.14.01.10","url":null,"abstract":"To evaluate the knowledge, awareness, and attitude (myths) of the general population about the first aid management of epistaxis. This cross-sectional study was conducted via an online questionnaire from March to August 2022. We generated google forms for data collection. The link to this google form was randomly shared on WhatsApp and Facebook platforms. A previously used questionnaire was used and tested in the pilot study over a sample of 20 participants. The questionnaire contained socio-demographic information including sex, age, occupation, and residence. Furthermore, the level of awareness was measured on behalf of epistaxis causes and actions which were further subdivided into many categories. Myths were also observed through a questionnaire For this cross-sectional study 407 participants aged 15 to 55 years were recruited. A total of 325 participants encountered epistaxis once in their lifetime. The 30% participants of in our study reported spontaneous epistaxis while 4.4% and 4.9% encountered it due to nasal trauma and fingernail trauma. In 7.6% of participants, epistaxis occurred due to bleeding disorders while 23% reported hypertension as the major reason. We observed that 94% population was familiar with the proper position that epistaxis patients required to control bleeding. Sitting with the head tilted forward as a coping mechanism was used in 48.9% of participants with 199 individuals practicing this while sitting with the head tilted backward was practiced by 117 (28.7%) participants. The general population had enough knowledge to manage epistaxis. The awareness levels of the population show a positive reflection of the healthcare system. However, we recommend that further studies should be conducted with a large sample size to evaluate the validity of our research.","PeriodicalId":41505,"journal":{"name":"Journal of Complementary Medicine Research","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75933138","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.5455/jcmr.2023.14.02.30
A. Selvaraj, A. Subramanian, Ashwin George, R. Shanmugam
Background: Green synthesized nanoparticles are perceived as an inexpensive, safe & ecologically beneficent approach to control pathogenic oral microbes compared to conventional methods. In the current study, silver nano particles (AgNPs) were effectively synthesised using clove and cardamom plant extracts. Methods: In the present study, aqueous silver nitrate was reacted with the clove, cardamom extracts and characterization was analyzed using UV-vis spectrophotometer and TEM analysis. Clove and cardamom reinforced silver nanoparticles were examined at 25 µL, 50 µL and 100 µL concentrations for their antibacterial activity against Staphylococcus aureus, Streptococcus mutans, Lactobacillus species and Candida albicans. Cytotoxicity was assessed using brine shrimp assays. Results: The formation of AgNPs was observed as shifting in color from orange-red color to dark brown at the end of the day three. Reducing silver ions to AgNPs, as shown by UV-vis spectroscopy, has produced an emission peak at 462 nm. TEM imaging showed that the particles were spherical and varied in size from 5-20 nm. Antimicrobial activity of the AgNPs at 100 µL was superior to that of antibiotics against Streptococcus mutans. Excellent antibacterial activity was shown by a zone of inhibition that was closer to that of antibiotics when examined against Lactobacillus. Staphylococcus aureus and Candida albicans were also moderately impacted. There was no evidence of cytotoxicity. Conclusion: Silver nanoparticles reinforced with clove and cardamom exhibited no cytotoxicity and showed promise as a potent antibacterial agent against oral pathogensKey words: silver nanoparticles.
{"title":"Novel eco-friendly synthesis of silver nanoparticles using clove and cardamom extracts and cytotoxic and antimicrobial efficacies against oral pathogens- In vitro study","authors":"A. Selvaraj, A. Subramanian, Ashwin George, R. Shanmugam","doi":"10.5455/jcmr.2023.14.02.30","DOIUrl":"https://doi.org/10.5455/jcmr.2023.14.02.30","url":null,"abstract":"Background: Green synthesized nanoparticles are perceived as an inexpensive, safe & ecologically beneficent approach to control pathogenic oral microbes compared to conventional methods. In the current study, silver nano particles (AgNPs) were effectively synthesised using clove and cardamom plant extracts. Methods: In the present study, aqueous silver nitrate was reacted with the clove, cardamom extracts and characterization was analyzed using UV-vis spectrophotometer and TEM analysis. Clove and cardamom reinforced silver nanoparticles were examined at 25 µL, 50 µL and 100 µL concentrations for their antibacterial activity against Staphylococcus aureus, Streptococcus mutans, Lactobacillus species and Candida albicans. Cytotoxicity was assessed using brine shrimp assays. Results: The formation of AgNPs was observed as shifting in color from orange-red color to dark brown at the end of the day three. Reducing silver ions to AgNPs, as shown by UV-vis spectroscopy, has produced an emission peak at 462 nm. TEM imaging showed that the particles were spherical and varied in size from 5-20 nm. Antimicrobial activity of the AgNPs at 100 µL was superior to that of antibiotics against Streptococcus mutans. Excellent antibacterial activity was shown by a zone of inhibition that was closer to that of antibiotics when examined against Lactobacillus. Staphylococcus aureus and Candida albicans were also moderately impacted. There was no evidence of cytotoxicity. Conclusion: Silver nanoparticles reinforced with clove and cardamom exhibited no cytotoxicity and showed promise as a potent antibacterial agent against oral pathogensKey words: silver nanoparticles.","PeriodicalId":41505,"journal":{"name":"Journal of Complementary Medicine Research","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77449212","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.5455/jcmr.2023.14.01.17
Twinkle Joshi, Vaishali Kuchewar, Kalpesh Gulve, Aman Chhabra
Ayurvedic treatment principle was applied in a case of Psoriatic Arthritis and the outcome was assessed. A 25-year-old female initially suffered from psoriasis. She took allopathic treatment for it. Two years later, she also developed multiple joint pain and due to involvement of knee and hip joints, her movements got restricted. The pain made her bed ridden. As she could not get significant improvement by mainstream medical treatments that she took for several months, the patient approached for Ayurvedic treatment. Considering the case similar to amavata because of the clinical features, the patient was treated by external and internal herbal preparations appropriate for the above said condition and was also advised for physiotherapy. The outcome of the treatments was monitored. Results: The treatment was found effective as the patient who was once bed ridden was now able to perform day to day activities which made her independent. Additionally, there were no side effects or complications. Thus, it could be concluded that this treatment protocol could be used for management of Psoriatic Arthritis. Also, these observations could form the basis for future clinical trial.
{"title":"Efficacy of Ayurvedic Drugs in the Management of Psoriatic Arthritis : A Case Study","authors":"Twinkle Joshi, Vaishali Kuchewar, Kalpesh Gulve, Aman Chhabra","doi":"10.5455/jcmr.2023.14.01.17","DOIUrl":"https://doi.org/10.5455/jcmr.2023.14.01.17","url":null,"abstract":"Ayurvedic treatment principle was applied in a case of Psoriatic Arthritis and the outcome was assessed. A 25-year-old female initially suffered from psoriasis. She took allopathic treatment for it. Two years later, she also developed multiple joint pain and due to involvement of knee and hip joints, her movements got restricted. The pain made her bed ridden. As she could not get significant improvement by mainstream medical treatments that she took for several months, the patient approached for Ayurvedic treatment. Considering the case similar to amavata because of the clinical features, the patient was treated by external and internal herbal preparations appropriate for the above said condition and was also advised for physiotherapy. The outcome of the treatments was monitored. Results: The treatment was found effective as the patient who was once bed ridden was now able to perform day to day activities which made her independent. Additionally, there were no side effects or complications. Thus, it could be concluded that this treatment protocol could be used for management of Psoriatic Arthritis. Also, these observations could form the basis for future clinical trial.","PeriodicalId":41505,"journal":{"name":"Journal of Complementary Medicine Research","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77537639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.5455/jcmr.2023.14.02.05
Hariprasath Nagarajan, D. Sakthi, M. Indiran, R. Shanmugam
Introduction: Nigella sativa, also known as black seed, black cumin, and/or Habbatul Barakah, is a medicinal herbal plant. Thymoquinone (TQ), one of Nigella sativa's active ingredients, has been shown to be anticarcinogenic, anti-inflammatory, analgesic, and antimicrobial. Hydroxyapatite (HA) is an inorganic mineral with the apatite lattice structure (A10(BO4)6C2). The aim of the current study is to incorporate thymoquinone with blackcumin hydroxyapatite crystals to form a new nanoformulation and to find out its cytotoxicity and antimicrobial properties against dental pathogens. Materials and method: Streptococcus mutans, Staphylococcus aureus, Enterococcus faecalis, and Candida albicans were the species used. The antimicrobial efficacy of the nanoparticles was evaluated using the agar well diffusion method at different concentrations ranging from 25 micron litres to 100 micron litres. UV double beam spectrophotometers in the wavelength range of 250-750nm were used to characterise the synthesised nanoparticles. Results: The zone of inhibition against Staphylococcus mutans and Candida albicans was found to be highest at 100 L concentration. As the concentrations of new nano formulation solution increased, the mean zone of inhibition grew. Conclusion: The study showed that there is potential antimicrobial property of the new nano formulation against Streptococcus mutans and Staphylococcus aureus also there is antifungal activity against Candida albicans
{"title":"Evaluation of antimicrobial property of thymoquinone synthesized with black cumin hydroxyapatite crystals against dental pathogens - An Invitro study","authors":"Hariprasath Nagarajan, D. Sakthi, M. Indiran, R. Shanmugam","doi":"10.5455/jcmr.2023.14.02.05","DOIUrl":"https://doi.org/10.5455/jcmr.2023.14.02.05","url":null,"abstract":"Introduction: Nigella sativa, also known as black seed, black cumin, and/or Habbatul Barakah, is a medicinal herbal plant. Thymoquinone (TQ), one of Nigella sativa's active ingredients, has been shown to be anticarcinogenic, anti-inflammatory, analgesic, and antimicrobial. Hydroxyapatite (HA) is an inorganic mineral with the apatite lattice structure (A10(BO4)6C2). The aim of the current study is to incorporate thymoquinone with blackcumin hydroxyapatite crystals to form a new nanoformulation and to find out its cytotoxicity and antimicrobial properties against dental pathogens. Materials and method: Streptococcus mutans, Staphylococcus aureus, Enterococcus faecalis, and Candida albicans were the species used. The antimicrobial efficacy of the nanoparticles was evaluated using the agar well diffusion method at different concentrations ranging from 25 micron litres to 100 micron litres. UV double beam spectrophotometers in the wavelength range of 250-750nm were used to characterise the synthesised nanoparticles. Results: The zone of inhibition against Staphylococcus mutans and Candida albicans was found to be highest at 100 L concentration. As the concentrations of new nano formulation solution increased, the mean zone of inhibition grew. Conclusion: The study showed that there is potential antimicrobial property of the new nano formulation against Streptococcus mutans and Staphylococcus aureus also there is antifungal activity against Candida albicans","PeriodicalId":41505,"journal":{"name":"Journal of Complementary Medicine Research","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73604949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.5455/jcmr.2023.14.02.16
Baher Felemban, Walaa Babgi, A. Bagasi, O. Felemban, Ehdaa Alturkistani, S. Aldahlawi, Abdel-Rahman Youssef
Background: Since chronic periodontitis has destroyed the root surface, it is challenging for fibroblast cells to bind to the root during root covering therapy. The ability of the gingival fibroblast to deposit collagen and regain attachment depends on the root surface microstructure; thus, the surface must be treated to be more compatible with gingiva cells. Aim of Study: The study aimed to compare the efficiency of EDTA/EMD root conditioning agents and the capability to modify the root surface at the microstructure grade to deliver a fundamental surface to stimulate fibroblast adherence. Materials and methods: Healthy extracted teeth were collected; a total of samples (n=30) have been split into a control group and four test groups, each with six samples. The test groups have been conditioned with either HA, 24% EDTA, EMD, or EDTA/EMD for two different time intervals. Fibroblast cells were planted on each sample and then incubated for 72 hours. Cell density in groups was determined using the MTT assay. Results: Adhesion of viable fibroblast to the root surface showed variable results with varied materials and application times. Generally, it was higher in the longer-time duration groups except for HA. The most favorable result was observed in the EDTA plus EMD group, followed by the EDTA group when applied for 4 minutes. The least favorable result is with HA after 2 minutes of application. Conclusion: EDTA plus EMD group display remarkable root surface modifications that induce fibroblast adhesion to the surface compared to other groups, as they showed a synergistic effect when applied to the same sample.
{"title":"EDTA/EMD as root chemical agents on enhancing the attachment of gingival fibroblast: In vitro study","authors":"Baher Felemban, Walaa Babgi, A. Bagasi, O. Felemban, Ehdaa Alturkistani, S. Aldahlawi, Abdel-Rahman Youssef","doi":"10.5455/jcmr.2023.14.02.16","DOIUrl":"https://doi.org/10.5455/jcmr.2023.14.02.16","url":null,"abstract":"Background: Since chronic periodontitis has destroyed the root surface, it is challenging for fibroblast cells to bind to the root during root covering therapy. The ability of the gingival fibroblast to deposit collagen and regain attachment depends on the root surface microstructure; thus, the surface must be treated to be more compatible with gingiva cells. Aim of Study: The study aimed to compare the efficiency of EDTA/EMD root conditioning agents and the capability to modify the root surface at the microstructure grade to deliver a fundamental surface to stimulate fibroblast adherence. Materials and methods: Healthy extracted teeth were collected; a total of samples (n=30) have been split into a control group and four test groups, each with six samples. The test groups have been conditioned with either HA, 24% EDTA, EMD, or EDTA/EMD for two different time intervals. Fibroblast cells were planted on each sample and then incubated for 72 hours. Cell density in groups was determined using the MTT assay. Results: Adhesion of viable fibroblast to the root surface showed variable results with varied materials and application times. Generally, it was higher in the longer-time duration groups except for HA. The most favorable result was observed in the EDTA plus EMD group, followed by the EDTA group when applied for 4 minutes. The least favorable result is with HA after 2 minutes of application. Conclusion: EDTA plus EMD group display remarkable root surface modifications that induce fibroblast adhesion to the surface compared to other groups, as they showed a synergistic effect when applied to the same sample.","PeriodicalId":41505,"journal":{"name":"Journal of Complementary Medicine Research","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85552083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective: Hyperparathyroidism can cause multiple organs damage, which is characterized by diversity and systemic. At present, there are mainly drug treatment and surgical treatment, among which surgical treatment has the highest cure rate. Surgical treatment mainly includes endoscopic and open surgery in clinical. This article systematically reviewed previously published trials on the two surgical methods, and provided an updated meta-analysis of the perioperative outcomes of different surgical methods on hyperparathyroidism. Methods: We searched 7 online databases home and abroad retrieval time till 3 February, 2021. We studied the influence of endoscopic and open surgery on the perioperative outcome of hyperparathyroidism. Data were processed with RevMan 5.3 and Stata 12.0. The methodological quality assessment of non-randomized clinical trials used risk of bias in non-randomised studies of interventions. The cochrane collaboration's tool for assessing bias risk was used to assess the quality of the included randomized controlled studies. The operation time, intraoperative blood loss, postoperative drainage volume and hospital stay were examined. Two authors exchanged and checked the extraction tables, and resolved any inconsistencies by discussing. Results: A total of 4 studies were included, including 124 patients and 246 controls. The combined results of random-effect model: WMD (95% CI)=-12.96 minutes (-43.47, 17.54) , P=0.40. Similarly, intraoperative blood loss, postoperative drainage volume and hospital stay also showed significant heterogeneity (I2>50%), but the combined results were statistically significant. Meta-analysis results of the three indicators (WMD (95%CI)) were as follows: -10.59 (-15.64, -5.54) mL, P<0.001; -11.69 (-19.65, -3.73) mL, P=0.004; -1.02 (-1.88, -0.16) days, P=0.02. In addition to the operation time, intraoperative blood loss, postoperative drainage volume and hospital stay of the intervention group were significantly lower than the control group. Conclusions: This paper concluded that endoscopic surgery showed certain advantages over open surgery in the treatment of hyperparathyroidism by performed the meta-analysis of clinical studies on the treatment of hyperparathyroidism, which the finding could provide theoretical guidance for clinical practice.
{"title":"Perioperative Outcomes of Endoscopic versus Open Operation in the Treatment of Hyperparathyroidism: A Systematic Review and Meta-analysis","authors":"Zhen Wu, Lili Yi, Yongkun Wang, Changxin Zhou, Shanping Sun, Yu-min Yao, Q. Lv, Jugao Fang","doi":"10.5455/jcmr.2023.14.01.06","DOIUrl":"https://doi.org/10.5455/jcmr.2023.14.01.06","url":null,"abstract":"Objective: Hyperparathyroidism can cause multiple organs damage, which is characterized by diversity and systemic. At present, there are mainly drug treatment and surgical treatment, among which surgical treatment has the highest cure rate. Surgical treatment mainly includes endoscopic and open surgery in clinical. This article systematically reviewed previously published trials on the two surgical methods, and provided an updated meta-analysis of the perioperative outcomes of different surgical methods on hyperparathyroidism. Methods: We searched 7 online databases home and abroad retrieval time till 3 February, 2021. We studied the influence of endoscopic and open surgery on the perioperative outcome of hyperparathyroidism. Data were processed with RevMan 5.3 and Stata 12.0. The methodological quality assessment of non-randomized clinical trials used risk of bias in non-randomised studies of interventions. The cochrane collaboration's tool for assessing bias risk was used to assess the quality of the included randomized controlled studies. The operation time, intraoperative blood loss, postoperative drainage volume and hospital stay were examined. Two authors exchanged and checked the extraction tables, and resolved any inconsistencies by discussing. Results: A total of 4 studies were included, including 124 patients and 246 controls. The combined results of random-effect model: WMD (95% CI)=-12.96 minutes (-43.47, 17.54) , P=0.40. Similarly, intraoperative blood loss, postoperative drainage volume and hospital stay also showed significant heterogeneity (I2>50%), but the combined results were statistically significant. Meta-analysis results of the three indicators (WMD (95%CI)) were as follows: -10.59 (-15.64, -5.54) mL, P<0.001; -11.69 (-19.65, -3.73) mL, P=0.004; -1.02 (-1.88, -0.16) days, P=0.02. In addition to the operation time, intraoperative blood loss, postoperative drainage volume and hospital stay of the intervention group were significantly lower than the control group. Conclusions: This paper concluded that endoscopic surgery showed certain advantages over open surgery in the treatment of hyperparathyroidism by performed the meta-analysis of clinical studies on the treatment of hyperparathyroidism, which the finding could provide theoretical guidance for clinical practice.","PeriodicalId":41505,"journal":{"name":"Journal of Complementary Medicine Research","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73165969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.5455/jcmr.2023.14.03.28
Fakiha K, Aljahdali A, Nouri L
Background: Despite the advances in treating burn injuries, burn severity remains one of the most challenging cases to be treated. As technologies advances, regenerative therapies using stem cells have been established and found to be effective and friendly as a regenerative tool. Stromal vascular fraction (SVF), extracted from adipose tissue, has a great potential for multipotent mesenchymal stem cells differentiation. Recent research has determined the therapeutic effects of SVF on burn injury. Previous finding has proved the efficacy of using SVF that is isolated enzymatically. This research aimed to examine the efficacy of allogenic mechanically isolated (MI) SVF in treating deep partial-thickness burns in a Wistar rat. Materials and Methods: After burn induction, 45 rats were divided into three groups of 15 as follows: group one (control, treated with phosphate-buffered saline), group two (treated with silver sulfadiazine (SSD), and group three (injected with SVF). SVF was harvested from the inguinal fat pad of six rats and mechanically processed. All injections were administered intradermally at the four edges of the burn to cover the entire wound bed. Morphological and histopathological analyses were performed for all groups at three different time points (4, 8, and 32 d post-treatment). Results: Treatment with MI SVF significantly reduced edema formation and dryness of the wound bed on day one compared to the control (P = 0.001). Histopathological results showed that SVF significantly reduced inflammation compared to the control (P = 0.045) on day one and increased neovascularization on day 8 (P = 0.016). Epithelial thickness was significantly greater in the SVF group compared to the SSD group (P = 0.034). Conclusions: The results of this study indicated the therapeutic potential of MI SVF on deep-partial-thickness burns by increasing neovascularization and epithelial thickness and reducing inflammation.
{"title":"Mechanically isolated stromal vascular fraction improves healing of deep-partial thickness burn in rat model","authors":"Fakiha K, Aljahdali A, Nouri L","doi":"10.5455/jcmr.2023.14.03.28","DOIUrl":"https://doi.org/10.5455/jcmr.2023.14.03.28","url":null,"abstract":"Background: Despite the advances in treating burn injuries, burn severity remains one of the most challenging cases to be treated. As technologies advances, regenerative therapies using stem cells have been established and found to be effective and friendly as a regenerative tool. Stromal vascular fraction (SVF), extracted from adipose tissue, has a great potential for multipotent mesenchymal stem cells differentiation. Recent research has determined the therapeutic effects of SVF on burn injury. Previous finding has proved the efficacy of using SVF that is isolated enzymatically. This research aimed to examine the efficacy of allogenic mechanically isolated (MI) SVF in treating deep partial-thickness burns in a Wistar rat. Materials and Methods: After burn induction, 45 rats were divided into three groups of 15 as follows: group one (control, treated with phosphate-buffered saline), group two (treated with silver sulfadiazine (SSD), and group three (injected with SVF). SVF was harvested from the inguinal fat pad of six rats and mechanically processed. All injections were administered intradermally at the four edges of the burn to cover the entire wound bed. Morphological and histopathological analyses were performed for all groups at three different time points (4, 8, and 32 d post-treatment). Results: Treatment with MI SVF significantly reduced edema formation and dryness of the wound bed on day one compared to the control (P = 0.001). Histopathological results showed that SVF significantly reduced inflammation compared to the control (P = 0.045) on day one and increased neovascularization on day 8 (P = 0.016). Epithelial thickness was significantly greater in the SVF group compared to the SSD group (P = 0.034). Conclusions: The results of this study indicated the therapeutic potential of MI SVF on deep-partial-thickness burns by increasing neovascularization and epithelial thickness and reducing inflammation.","PeriodicalId":41505,"journal":{"name":"Journal of Complementary Medicine Research","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82170679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.5455/jcmr.2023.14.01.13
Samera F. AlBasri, Hanan AlShomrani
Objective: To estimate the frequency and associated factors of vaginal flatus “wind” among women attending gynecology clinic at King Abdulaziz university hospital. Materials and methods: This prospective cohort study included women attending the gynecology clinic for routine pelvic gynecology examination and used a non-validated questionnaire to investigate the presence of vaginal wind and related factors. Results: The cohort included 41 women who were interviewed by a physician after their verbal consent was obtained. Their demographic and clinical data were analyzed in relation to the presence or absence of vaginal wind. Conclusion: Our findings indicate that vaginal wind is a common, but bothersome, symptom among sexually active women. It may be associated with pelvic organ prolapse
{"title":"Vaginal wind: A Silent but Common Symptom","authors":"Samera F. AlBasri, Hanan AlShomrani","doi":"10.5455/jcmr.2023.14.01.13","DOIUrl":"https://doi.org/10.5455/jcmr.2023.14.01.13","url":null,"abstract":"Objective: To estimate the frequency and associated factors of vaginal flatus “wind” among women attending gynecology clinic at King Abdulaziz university hospital. Materials and methods: This prospective cohort study included women attending the gynecology clinic for routine pelvic gynecology examination and used a non-validated questionnaire to investigate the presence of vaginal wind and related factors. Results: The cohort included 41 women who were interviewed by a physician after their verbal consent was obtained. Their demographic and clinical data were analyzed in relation to the presence or absence of vaginal wind. Conclusion: Our findings indicate that vaginal wind is a common, but bothersome, symptom among sexually active women. It may be associated with pelvic organ prolapse","PeriodicalId":41505,"journal":{"name":"Journal of Complementary Medicine Research","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82538282","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.5455/jcmr.2023.14.03.20
Daniyal Ibragimov, Mariia K. Soboleva, Yulia Dmitrievna Dementyeva, Sofiia Roshchupkina, R. Bakhtiiarov, Elena Petrenko
Medical ethics or medical deontology is a set of ethical norms and principles of behavior of medical workers in the performance of their professional duties, i.e. deontology provides mainly norms of relationships with the patient. In the medical understanding, deontology is the teaching of legal, professional and moral duties and rules of conduct of a medical worker in relation to a patient. In addition, deontology establishes norms of relationships between medical professionals and relatives of patients, as well as between colleagues in the medical team. The article is a study of ethical aspects related to medical practice. Doctors and other medical professionals face many ethical dilemmas that require making difficult decisions in their daily work. The purpose of this study is to analyze various ethical problems faced by medical professionals and identify the basic ethical principles that help them make decisions in these situations. A medical worker should always remember about the patient, have the ability to conquer and subdue the soul of the patient. The core issues of medical ethics and deontology are the relationship between a medical worker and a patient. The personality and appearance of a medical worker are determined by the economic, political and social conditions of the society in which he works. The paper discusses several ethical dilemmas faced by doctors, such as confidentiality and protection of patients' personal data, principles of fairness and accessibility of medical care, as well as ethical issues that arise when making decisions about consultations, consent to treatment and termination of a patient's life. It also examines the various ethical principles that medical personnel apply to solve these dilemmas, such as the principles of benevolence, non-harm, respect for patient autonomy and justice.
{"title":"Ethical Aspects in Medical Practice: Investigation of Ethical Dilemmas and Principles Related to Medical Practice","authors":"Daniyal Ibragimov, Mariia K. Soboleva, Yulia Dmitrievna\u0000Dementyeva, Sofiia Roshchupkina, R. Bakhtiiarov, Elena Petrenko","doi":"10.5455/jcmr.2023.14.03.20","DOIUrl":"https://doi.org/10.5455/jcmr.2023.14.03.20","url":null,"abstract":"Medical ethics or medical deontology is a set of ethical norms and principles of behavior of medical workers in the performance of their professional duties, i.e. deontology provides mainly norms of relationships with the patient. In the medical understanding, deontology is the teaching of legal, professional and moral duties and rules of conduct of a medical worker in relation to a patient. In addition, deontology establishes norms of relationships between medical professionals and relatives of patients, as well as between colleagues in the medical team. The article is a study of ethical aspects related to medical practice. Doctors and other medical professionals face many ethical dilemmas that require making difficult decisions in their daily work. The purpose of this study is to analyze various ethical problems faced by medical professionals and identify the basic ethical principles that help them make decisions in these situations. A medical worker should always remember about the patient, have the ability to conquer and subdue the soul of the patient. The core issues of medical ethics and deontology are the relationship between a medical worker and a patient. The personality and appearance of a medical worker are determined by the economic, political and social conditions of the society in which he works. The paper discusses several ethical dilemmas faced by doctors, such as confidentiality and protection of patients' personal data, principles of fairness and accessibility of medical care, as well as ethical issues that arise when making decisions about consultations, consent to treatment and termination of a patient's life. It also examines the various ethical principles that medical personnel apply to solve these dilemmas, such as the principles of benevolence, non-harm, respect for patient autonomy and justice.","PeriodicalId":41505,"journal":{"name":"Journal of Complementary Medicine Research","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76324343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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