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Paucity of Published Data and Protocols for Hypoglycemia Management in Long-term Care. 长期护理中低血糖管理的公开数据和规程很少。
Q2 Medicine Pub Date : 2024-10-01 DOI: 10.4140/TCP.n.2024.373
Matthew R Krecic, James Meyer, Kathleen J Chavanu

Background: Older people with diabetes are at high risk for hypoglycemia. Implementing a hypoglycemia treatment protocol in long-term care (LTC) settings may positively affect patient-related outcomes and health care resource utilization and costs. Anecdotal experience indicates little has been studied and published regarding this clinical practice. Objective: To identify hypoglycemia treatment protocols established for LTC settings and assess their effects on patient-related outcomes and health care resource use. Data Sources: The authors performed a systematic literature search of English-language articles and abstracts published between January 1, 2003 (PubMed), or 2018 (Google Scholar) and May 10, 2023. Search terms were "hypoglycemia," "diabetes mellitus," "longterm care," "nursing facilities," "assisted living facilities," "geriatrics," "elderly," "aged," "disabled," "disease management," "evidence-based medicine," "clinical protocols," "guideline," "glucagon," and/or "blood glucose." Included were publications with hypoglycemia treatment and management protocols or hypoglycemia-specific recommendations for LTC settings. DATA SYNTHESIS: The authors identified 405 articles and abstracts, removed 36 duplicates, screened 369 titles/ abstracts, and analyzed the full text for 93. Five met the inclusion criteria. Two originated from the American Diabetes Association: 2016 position statement regarding the management of diabetes in LTC and skilled nursing facilities, and 2023 standard-of-care guideline for managing older people with diabetes. One included the results after implementing an overall diabetes clinical care management algorithm in LTC facilities. A 2020 abstract and 2019 article were the only 2 publications involving specific hypoglycemia treatment protocols in LTC settings. Conclusion: This systematic literature search identified lack of published hypoglycemia treatment protocols in LTC settings and their effects on patient outcomes.

背景:老年糖尿病患者是低血糖的高危人群。在长期护理(LTC)环境中实施低血糖治疗方案可能会对患者的相关治疗效果、医疗资源利用率和成本产生积极影响。轶事经验表明,有关这一临床实践的研究和发表很少。目的确定为长期护理机构制定的低血糖治疗方案,并评估其对患者相关预后和医疗资源使用的影响。数据来源:作者对 2003 年 1 月 1 日(PubMed)或 2018 年(Google Scholar)至 2023 年 5 月 10 日期间发表的英文文章和摘要进行了系统的文献检索。检索词为 "低血糖"、"糖尿病"、"长期护理"、"护理设施"、"生活辅助设施"、"老年医学"、"老年人"、"老年人"、"残疾人"、"疾病管理"、"循证医学"、"临床协议"、"指南"、"胰高血糖素 "和/或 "血糖"。其中包括低血糖治疗和管理方案或针对 LTC 环境的低血糖特定建议的出版物。数据合成:作者确定了 405 篇文章和摘要,删除了 36 篇重复文章,筛选了 369 篇标题/摘要,并分析了 93 篇文章的全文。其中五篇符合纳入标准。其中两篇来自美国糖尿病协会:2016 年关于 LTC 和专业护理机构糖尿病管理的立场声明,以及 2023 年老年糖尿病患者管理标准指南。其中一篇包括在 LTC 机构中实施整体糖尿病临床护理管理算法后的结果。2020 年的一篇摘要和 2019 年的一篇文章是仅有的两篇涉及 LTC 机构中特定低血糖治疗方案的出版物。结论本次系统性文献检索发现,缺乏已发表的 LTC 机构低血糖治疗方案及其对患者预后的影响。
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引用次数: 0
Changing Medication Safety and Quality Improvements: Empowering Pharmacists With Data. 改变用药安全和提高质量:用数据增强药剂师的能力。
Q2 Medicine Pub Date : 2024-10-01 DOI: 10.4140/TCP.n.2024.393
Leigh Davitian
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引用次数: 0
The Many Benefits of Sharing Data in Professional Practice. 专业实践中共享数据的诸多益处。
Q2 Medicine Pub Date : 2024-10-01 DOI: 10.4140/TCP.n.2024.344
Chris Alderman
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引用次数: 0
Embracing the Changing Season: Quantifying Pharmacy's Role in Improving Medication Quality and Safety. 拥抱变化的季节:量化药房在提高用药质量和安全方面的作用。
Q2 Medicine Pub Date : 2024-10-01 DOI: 10.4140/TCP.n.2024.346
Micah Cost
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引用次数: 0
Geriatric Pharmacotherapy Case Series: Medications for Diabetes-A Focus on Secondary Stroke Prevention. 老年药物治疗病例系列:糖尿病药物治疗--关注中风二级预防。
Q2 Medicine Pub Date : 2024-10-01 DOI: 10.4140/TCP.n.2024.350
Sabrina Warren, Shayla McKee, Erin Yakiwchuk

This report addresses evidence for efficacy of diabetes medications with a focus on stroke risk reduction. The cardiovascular benefits of SGLT-2 inhibitors and GLP-1 receptor agonists have been well-established; however, clinical trials to date have examined composite cardiovascular endpoints that include, but do not specifically focus on, stroke. The purpose of this case review is to examine the evidence for the various diabetes medications in reducing the risk for stroke. This literature review was inspired by a patient seen in a geriatric day hospital program with diabetes and a history of multiple strokes. Our goal was to select a diabetes management regimen that would provide both glycemic control and stroke risk reduction. As diabetes and cerebrovascular disease commonly coexist and are important contributors to morbidity and mortality in older individuals, appropriate management must incorporate both current evidence as well as consideration for patient-specific factors that may influence the treatment plan. This patient case illustrates the importance of both.

本报告探讨糖尿病药物的疗效证据,重点是降低中风风险。SGLT-2 抑制剂和 GLP-1 受体激动剂对心血管的益处已得到充分证实;然而,迄今为止的临床试验研究了包括中风在内的复合心血管终点,但并未特别关注中风。本病例回顾旨在研究各种糖尿病药物降低中风风险的证据。本文献综述的灵感来源于一位在老年病日间医院就诊的患者,该患者患有糖尿病并有多次中风病史。我们的目标是选择一种既能控制血糖又能降低中风风险的糖尿病治疗方案。由于糖尿病和脑血管疾病通常同时存在,并且是导致老年人发病率和死亡率的重要因素,因此适当的管理必须结合当前的证据,并考虑可能影响治疗计划的患者特异性因素。本病例说明了两者的重要性。
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引用次数: 0
Assessing the Impact of Consultant Pharmacist-Directed Anticoagulation Management in the Post-Acute and Long-Term Care (PALTC) Setting. 评估药剂师顾问指导的抗凝管理在急性期后和长期护理 (PALTC) 环境中的影响。
Q2 Medicine Pub Date : 2024-10-01 DOI: 10.4140/TCP.n.2024.382
Alexandra Schifano, Alexandra Statczar, Anne Metzger, Jaron Stout, Jeffrey A Clark, Casondra Seibert

Objective: The objective is to evaluate the impact of consultant pharmacist-directed anticoagulation management in the post-acute and long-term care (PALTC) setting. Design: Retrospective study. Participants: Patients whose clinical details were included in the ASCP aggregate data and were older than 65 years of age, admitted to PALTC facility, and had active anticoagulant therapy were included in the study. Interventions: Pharmacists enrolled in the ASCP (Quality Improvement Project) and performed monthly chart reviews per standard practice. The 30-day post-chart review follow-up data were entered into the ASCP data collection. The research team assessed for consultant pharmacist interventions associated with anticoagulant therapy management. Results: Data were collected from November 2022 through March 2023, during which 807 charts were assessed. Within the charts reviewed, 274 patients received anticoagulation therapy, of which 173 (63%) were identified as having a medication-related problem concerning anticoagulant use. Two hundred sixteen pharmacist recommendations were sent to providers to address the inappropriate anticoagulant therapy. Providers completed modifications to 190 (88%) of the recommendations. Conclusion: This study emphasized pharmacist involvement in managing anticoagulant therapy within the PALTC setting and identified the need for further investigation of patient specific outcomes.

目的目的: 评估顾问药剂师指导的抗凝管理在急性期后和长期护理 (PALTC) 环境中的影响。设计:回顾性研究。参与者:研究对象包括临床详情被纳入 ASCP 总数据、年龄超过 65 岁、入住 PALTC 机构并接受积极抗凝治疗的患者。干预措施:药剂师加入 ASCP(质量改进项目),并按照标准做法每月进行病历审查。病历审查后 30 天的随访数据被输入 ASCP 数据收集系统。研究小组评估了与抗凝治疗管理相关的顾问药剂师干预措施。结果:数据收集时间为 2022 年 11 月至 2023 年 3 月,期间评估了 807 份病历。在审查的病历中,有 274 名患者接受了抗凝治疗,其中 173 人(63%)被确认存在与抗凝剂使用相关的用药问题。药剂师向医疗服务提供者发送了 216 份建议,以解决抗凝疗法不当的问题。医疗服务提供者完成了对其中 190 项(88%)建议的修改。结论:这项研究强调了药剂师在 PALTC 环境中参与管理抗凝疗法的重要性,并确定了进一步调查患者具体结果的必要性。
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引用次数: 0
Heart Failure in Older People Part 2: Guideline-Directed Medical Therapy. 老年人心力衰竭第二部分:指南指导下的药物治疗。
Q2 Medicine Pub Date : 2024-10-01 DOI: 10.4140/TCP.n.2024.360
Elizabeth Pogge, Stephanie Sibicky

Heart failure is a common cardiovascular disease that affects older people and has a high rate of mortality. Treatment for heart failure has evolved in the past 10 years to include novel evidence-based agents as well as changes in how medications are initiated and up-titrated. Despite evidence of the importance of using four guideline-directed medications, older people are often undertreated with these lifesaving therapies. Senior care pharmacists play an important role in heart failure management among older people by providing therapeutic recommendations; monitoring therapeutic interventions; and educating patients, caregivers, and/ or providers.

心力衰竭是一种影响老年人的常见心血管疾病,死亡率很高。在过去的 10 年中,心力衰竭的治疗不断发展,包括基于证据的新型药物,以及药物启动和升级方式的改变。尽管有证据表明使用四种指南指导的药物非常重要,但老年人对这些救命疗法的使用往往不足。老年护理药剂师通过提供治疗建议、监测治疗干预措施以及教育患者、护理人员和/或医疗服务提供者,在老年人心力衰竭管理中发挥着重要作用。
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引用次数: 0
It Takes a Village…. It Takes a Village....
Q2 Medicine Pub Date : 2024-08-01 DOI: 10.4140/TCP.n.2024.283
Gauri Godbole
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引用次数: 0
Does the Pharmacy Profession View the Full Picture of Cognitive Disorders? 药学专业是否了解认知障碍的全貌?
Q2 Medicine Pub Date : 2024-08-01 DOI: 10.4140/TCP.n.2024.281
Chris Alderman
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引用次数: 0
Impact of a Delirium Protocol on Deliriogenic Medication Use in Hospitalized Older Veterans. 谵妄协议对住院老年退伍军人谵妄性药物使用的影响。
Q2 Medicine Pub Date : 2024-08-01 DOI: 10.4140/TCP.n.2024.291
Alison M Weygint, Brandon LaMarr, Stephanie Lee

Background The Southern Arizona VA Health Care System (SAVAHCS) implemented a delirium prevention and treatment protocol in 2019. Objective The primary objective of this study was to determine if the implementation of a delirium protocol influenced deliriogenic medication use in hospitalized geriatric veterans. The secondary objectives were to compare the rates of delirium diagnosis, hospital length-of-stay, and rates of newly started deliriogenic medications during admission pre- and post-protocol. Methods This study was a retrospective, secondary data analysis study. Veterans 65 years of age and older who were admitted to an inpatient medical ward at the SAVAHCS for 24 hours or more between January 1, 2018 and December 31, 2018 (pre-protocol) or January 1, 2021 and December 31, 2021 (post-protocol) were included. Patients were excluded if they had a diagnosis of alcohol or benzodiazepine withdrawal upon admission. Results A total of 5491 patients were included in this study; 2940 (53.5%) in the pre-protocol group and 2551 (46.5%) in the post-protocol group. Patients received at least one deliriogenic medication during their admission in the post-protocol group (36.2%) compared with the pre-protocol group (34.1%), but there was no statistically significant difference (P = 0.098). There were also no significant differences in the rates of documentation of delirium as a diagnosis at discharge, hospital length-of-stay, or the rates of newly started deliriogenic medications during admission between the groups. Conclusion Implementation of a delirium prevention and treatment protocol at the SAVAHCS did not significantly impact the use of deliriogenic medications in hospitalized geriatric veterans.

背景 南亚利桑那州退伍军人医疗保健系统(SAVAHCS)于 2019 年实施了谵妄预防和治疗方案。目标 本研究的首要目标是确定谵妄协议的实施是否会影响住院老年退伍军人的谵妄药物使用。次要目标是比较谵妄诊断率、住院时间以及入院前和入院后新开始使用致谵妄药物的比率。方法 本研究是一项回顾性二次数据分析研究。研究对象包括在 2018 年 1 月 1 日至 2018 年 12 月 31 日(协议前)或 2021 年 1 月 1 日至 2021 年 12 月 31 日(协议后)期间入住 SAVAHCS 住院病房 24 小时及以上的 65 岁及以上退伍军人。入院时诊断为酒精或苯二氮卓类药物戒断的患者排除在外。结果 本研究共纳入 5491 例患者,其中协议前组 2940 例(53.5%),协议后组 2551 例(46.5%)。与方案前组(34.1%)相比,方案后组(36.2%)患者在入院期间至少服用了一种脱利米松药物,但两者之间没有显著的统计学差异(P = 0.098)。此外,两组患者在出院时将谵妄作为诊断的记录率、住院时间或入院时新开始服用致谵妄药物的比例也无明显差异。结论 在SAVAHCS实施谵妄预防和治疗方案不会对住院老年退伍军人使用致谵妄药物产生明显影响。
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Senior Care Pharmacist
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