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Age-Friendly Approaches to Managing Mentation, A Delirium Case Review. 年龄友好的方法管理精神状态,谵妄病例回顾。
Q2 Medicine Pub Date : 2026-01-01 DOI: 10.4140/TCP.n.2026.13
Jennifer Urso, Donna Fick

Delirium is common among older adults in post-acute care and often goes unrecognized, particularly when presenting with hypoactive or mixed features. This case example describes an 85-year-old man admitted to an inpatient rehabilitation facility after hip fracture repair who developed acute confusion, inattention, fluctuating consciousness, and functional decline five days into his stay. Guided by the Age-Friendly 4Ms framework, the interdisciplinary team addressed underlying causes. Within one week, the patient demonstrated substantial improvement. This case highlights the critical role of early recognition, interdisciplinary collaboration, and evidence-based pharmacologic and nonpharmacologic interventions in managing delirium, emphasizing how the 4Ms of Age-Friendly care can optimize recovery and support a return to baseline function in older adults.

谵妄在急症后护理的老年人中很常见,通常不被识别,特别是当表现为活动减退或混合特征时。本案例描述了一名85岁的男性在髋部骨折修复后住院康复机构,他在住院5天后出现急性意识模糊、注意力不集中、意识波动和功能下降。在“高龄友好”框架的指导下,跨学科团队解决了根本原因。在一周内,患者表现出明显的改善。本病例强调了早期识别、跨学科合作以及基于证据的药物和非药物干预在谵妄管理中的关键作用,强调了老年友好护理的4Ms如何优化老年人的康复并支持其恢复到基线功能。
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引用次数: 0
Comparing ASHP and PQA Frameworks for Identifying Medication Therapy Problems in Older Adults with COPD Discharged to Home Health Care: A Cross-Sectional Study. 比较ASHP和PQA框架在识别老年COPD患者出院后接受家庭保健的药物治疗问题:一项横断面研究。
Q2 Medicine Pub Date : 2026-01-01 DOI: 10.4140/TCP.n.2026.34
Avery North, Grant H Skrepnek, Richard Matthew Atkins, Joanne Skaggs, Huimin Wu, Paul M Boylan

Background Almost 900,000 patients in the United States living with chronic obstructive pulmonary disease (COPD) require home health care each year. Pharmacists are integral members of the home health care team, especially for older adults living with COPD, because of their expertise in identifying and resolving medication therapy problems (MTPs) during transitions of care. Objective To identify, characterize, and compare the quantities and categories of MTPs in older adults living with COPD who require home health care following hospital discharge. Methods This cross-sectional study involved adults aged 65 years and older living with COPD who were discharged from an academic medical center between June 1, 2023, and November 30, 2023. MTPs were classified using two frameworks: the American Society of Health-System Pharmacists (ASHP) and the Pharmacy Quality Alliance (PQA). Results During the study period, 535 older adults were prescribed home health care, 15 of whom had a hospitalization discharge diagnosis of COPD and were screened for inclusion. Among the 13 patients eligible for inclusion, 92.3% experienced one or more MTPs. Almost 80% of the identified MTPs involved issues related to medication indication: 50% of this cross-sectional cohort were not prescribed medications when clinically indicated, and up to 40% of patients were prescribed medications without apparent indications. The ASHP framework identified more than twice the number of MTPs compared to the PQA framework. Conclusion The ASHP framework may identify more MTPs than the PQA framework in older adults living with COPD who require home health care upon discharge. Further research evaluating pharmacist interventions related to MTPs would be beneficial across diverse settings and patient populations.

背景:在美国,每年有近90万慢性阻塞性肺疾病(COPD)患者需要家庭保健。药剂师是家庭卫生保健团队不可或缺的成员,特别是对于患有慢性阻塞性肺病的老年人,因为他们在护理过渡期间识别和解决药物治疗问题(MTPs)方面的专业知识。目的确定、表征并比较出院后需要家庭保健的老年COPD患者MTPs的数量和类别。方法:本横断面研究纳入了2023年6月1日至2023年11月30日期间从学术医疗中心出院的65岁及以上COPD患者。mtp采用美国卫生系统药师协会(ASHP)和药学质量联盟(PQA)两个框架进行分类。结果在研究期间,535名老年人接受了家庭保健,其中15人有COPD住院出院诊断,并进行了纳入筛查。在13名符合纳入条件的患者中,92.3%的患者经历了一次或多次mtp。几乎80%已确定的MTPs涉及与药物指征相关的问题:该横断面队列中50%的患者在临床指征时没有处方药物,高达40%的患者在没有明显指征的情况下服用处方药。与PQA框架相比,ASHP框架确定的mtp数量是PQA框架的两倍多。结论在老年COPD患者出院后需要家庭保健时,ASHP框架可能比PQA框架识别出更多的mtp。进一步的研究评估与MTPs相关的药剂师干预措施将在不同的环境和患者群体中有益。
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引用次数: 0
2025 New Drug Update (Part 2): Recent Approvals and Clinical Implications. 2025年新药更新(第二部分):近期批准和临床意义
Q2 Medicine Pub Date : 2026-01-01 DOI: 10.4140/TCP.n.2026.3
Sophie Friedman, Kyle Akerman, Carla Bouwmeester

With the increasing prevalence of polypharmacy, age-related physiological changes, and the need for individualized pharmacotherapy in older patients, understanding new drug approvals is crucial to optimizing medication management. This review synthesizes the latest evidence on recently approved medications including Atzumi™ and Brekiya® (dihydroergotamine mesylate) for migraine headaches, Attruby™ (acoramidis) for transthyretin amyloid cardiomyopathy, and Blujepa® (gepotidacin) for uncomplicated urinary tract infections. Insights are offered into prescribing considerations for these agents in older populations, potential drug-drug interactions, and administration and handling tips. This work will be of significant interest to health care professionals as they evaluate the appropriateness of these new therapeutic options.

随着多种药物的日益流行,年龄相关的生理变化,以及老年患者对个性化药物治疗的需求,了解新药批准对于优化药物管理至关重要。本综述综合了最近批准的药物的最新证据,包括治疗偏头痛的Atzumi™和Brekiya®(甲磺酸二氢麦角胺),治疗转甲状腺素淀粉样心肌病的Attruby™(acoramidis),以及治疗无并发症尿路感染的Blujepa®(gepotidacin)。对老年人群中这些药物的处方考虑、潜在的药物-药物相互作用以及给药和处理提示提供了见解。这项工作将是显著的兴趣卫生保健专业人员,因为他们评估这些新的治疗方案的适当性。
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引用次数: 0
Interdisciplinary Approach to Fall Risk Mitigation in an Older Adult with Atrial Fibrillation. 多学科方法降低老年房颤患者跌倒风险。
Q2 Medicine Pub Date : 2026-01-01 DOI: 10.4140/TCP.n.2026.21
Elizabeth K Pogge, Lindsay E Davis, John Tuitele, Nisha Bhatia

In this case study, an interdisciplinary team of clinicians, including a clinical pharmacist, cardiologist, and physical therapist, presents an approach to assessing, mitigating, and engaging in shared decision-making for fall risk reduction in an older adult through lifestyle modifications, physical activity, and medication regimen adjustments. This case explores a frequently encountered clinical dilemma: balancing the safe use of oral anticoagulants for stroke prevention in atrial fibrillation (AF) with the risks associated with recurrent falls-an area where shared decision-making is crucial. It also highlights the value of an interdisciplinary team utilizing the Age-Friendly Health Systems 4Ms framework, which focuses on aligning care with what matters most to the older adult.

在这个案例研究中,一个跨学科的临床医生团队,包括临床药剂师、心脏病专家和物理治疗师,提出了一种评估、减轻和参与共同决策的方法,通过改变生活方式、身体活动和调整药物治疗方案来降低老年人跌倒风险。本病例探讨了一个经常遇到的临床困境:平衡口服抗凝剂预防房颤(AF)卒中的安全使用与复发跌倒相关的风险-这是一个共同决策至关重要的领域。它还强调了跨学科团队利用老年人友好卫生系统4Ms框架的价值,该框架侧重于将护理与老年人最重要的事项结合起来。
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引用次数: 0
Reflecting on the Value of Mentors. 反思导师的价值。
Q2 Medicine Pub Date : 2026-01-01 DOI: 10.4140/TCP.n.2026.1
Demetra Antimisiaris, Patricia W Slattum
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引用次数: 0
Twists, Turns, and Turbulence: Healthcare Policy's Wild Ride in 2025. 曲折、转折和动荡:2025年医疗政策的疯狂之旅。
Q2 Medicine Pub Date : 2025-12-01 DOI: 10.4140/TCP.n.2025.526
Leigh Davitian
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引用次数: 0
2025 ASCP Research & Education Poster Abstracts: Presented at the ASCP Annual Meeting & Exhibition Town and Country Resort, San Diego, California October 23-26, 2025. 2025年ASCP研究与教育海报摘要:于2025年10月23日至26日在加州圣地亚哥举行的ASCP年会及展览会上发表。
Q2 Medicine Pub Date : 2025-12-01
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引用次数: 0
Guiding ASCP Forward with Purpose and Passion. 用目标和激情引导ASCP前进。
Q2 Medicine Pub Date : 2025-12-01 DOI: 10.4140/TCP.n.2025.487
Joanne Kaldy
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引用次数: 0
Navigating the New F-605: Collaboration and Compliance in Psychotropic Medication Use. 导航新的F-605:精神药物使用中的协作和依从性。
Q2 Medicine Pub Date : 2025-12-01 DOI: 10.4140/TCP.n.2025.498
Demetra Antimisiaris
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引用次数: 0
The Pharmacist's Role in Patient Safety During Transitions of Care. 在护理过渡期间药剂师在患者安全中的作用。
Q2 Medicine Pub Date : 2025-12-01 DOI: 10.4140/TCP.n.2025.501
Joanne Kaldy
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引用次数: 0
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Senior Care Pharmacist
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