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Examining the impact of Anticholinergic Burden on Hospitalized Older People Receiving Concomitant Cholinesterase inhibitors. 检查抗胆碱能负担对住院老年人同时使用胆碱酯酶抑制剂的影响。
Q2 Medicine Pub Date : 2024-12-01 DOI: 10.4140/TCP.n.2024.449
Jiajie Guan, John Noviasky, Jonathan H Watanabe

Background: Cholinesterase (ChE) inhibitors enhance central cholinergic function and are considered as standard treatments to ameliorate symptoms relating to Alzheimer's disease. Though anticholinergic medications directly antagonize the effects of ChE inhibitors, they are commonly prescribed among hospitalized adults. Objective: To determine the impact of high anticholinergic burden (ACB) on length of stay (LOS) and 30-day readmission rates among hospitalized patients receiving concomitant ChE inhibitors. Methods: This was a retrospective cohort study conducted at a tertiary care academic medical center involving hospitalized patients on medical floors who received any Food and Drug Administration-approved ChE inhibitors during their hospital stay from October 1, 2022, to September 30, 2023. The primary outcome of the study was to compare hospital LOS among patients with high (ACB ≥ 3) versus low (ACB < 3) ACB. The secondary outcome was to assess the impact of ACB burden on 30-day readmission rates. Results: Among hospitalized adults, patients with high ACB exposure had a significantly longer hospital LOS (median: 5.50 vs 4.25 days; P < 0.001) than patients with low ACB exposure, after adjusting for covariates. Analysis of secondary outcome revealed that though the high ACB group had a higher 30-day readmission rate compared with the lower ACB group (6.8% vs. 2.2%), the difference was not statistically significant (OR = 3.46, 95% CI 0.85-14.08; P = 0.083). Conclusion: A high ACB exposure among older individuals taking concurrent ChE inhibitors is associated with a longer hospital stay.

背景:胆碱酯酶(ChE)抑制剂增强中枢胆碱能功能,被认为是改善阿尔茨海默病相关症状的标准治疗方法。虽然抗胆碱能药物直接拮抗胆碱抑制剂的作用,但它们通常在住院成人中使用。目的:探讨高抗胆碱能负荷(ACB)对合并使用ChE抑制剂的住院患者住院时间(LOS)和30天再入院率的影响。方法:这是一项在三级医疗学术医疗中心进行的回顾性队列研究,涉及从2022年10月1日至2023年9月30日期间在医疗楼层接受任何食品和药物管理局批准的ChE抑制剂的住院患者。本研究的主要结局是比较ACB高(ACB≥3)和低(ACB < 3) ACB患者的医院LOS。次要结局是评估ACB负担对30天再入院率的影响。结果:在住院成人中,高ACB暴露的患者的住院LOS明显更长(中位数:5.50 vs 4.25天;在调整协变量后,P < 0.001)比低ACB暴露的患者。次要结局分析显示,虽然高ACB组的30天再入院率高于低ACB组(6.8%比2.2%),但差异无统计学意义(OR = 3.46, 95% CI 0.85-14.08;P = 0.083)。结论:在同时服用ChE抑制剂的老年人中,高ACB暴露与更长的住院时间有关。
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引用次数: 0
Ethical Geriatric Pharmacy: Combating Ageism and Enhancing Patient Care. 伦理老年药学:打击老年歧视和加强病人护理。
Q2 Medicine Pub Date : 2024-12-01 DOI: 10.4140/TCP.n.2024.441
Madeline M Yuzwa

While there is existing literature on medical ethics and geriatric care, this paper offers a unique perspective by examining the specific ethical challenges and obligations faced by pharmacists caring for older people. It provides a comprehensive ethical framework tailored to this specialized area of pharmacy practice. The findings and recommendations presented in this paper have significant implications for enhancing patient-centered, ethically grounded care for older people in pharmacy settings. It offers practical guidance for navigating complex ethical dilemmas and upholding the highest standards of care for this vulnerable population.

虽然已有关于医学伦理和老年护理的文献,但本文通过研究药剂师照顾老年人所面临的具体伦理挑战和义务,提供了一个独特的视角。它提供了一个全面的道德框架量身定制的这一专业领域的药房实践。本文提出的研究结果和建议对加强以患者为中心、以伦理为基础的药房老年人护理具有重要意义。它为应对复杂的道德困境和维护对弱势群体的最高护理标准提供了实用指导。
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引用次数: 0
Leading Pharmacists Who Experience Patient Loss. 经历病人流失的主要药剂师。
Q2 Medicine Pub Date : 2024-12-01 DOI: 10.4140/TCP.n.2024.445
Marlene Nguyen, Donna M Breese, Kristin Kellett

Health care providers, at some point in their careers, will experience grief and loss of a patient. Grief is a natural response that many people experience, especially working in those fields such as community pharmacy, hospitals, hospice, and others. Pharmacists serve as community leaders and need to be properly trained early on how to deal with grief and loss both personally and within their teams. Pharmacist leaders can lead their team through hard times by developing a toolbox of skills. These skills include emotional intelligence, communication, and leadership skills to work through personal grief.

卫生保健提供者,在他们职业生涯的某个阶段,会经历悲伤和失去病人。悲伤是许多人都会经历的一种自然反应,尤其是在社区药房、医院、临终关怀等领域工作的人。药剂师是社区的领导者,需要及早接受适当的培训,学习如何处理个人和团队内部的悲伤和损失。药剂师领导可以通过发展技能工具箱来带领他们的团队度过困难时期。这些技能包括情商、沟通能力和克服个人悲伤的领导能力。
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引用次数: 0
Notes on the Consultant Pharmacist Practice Model: At Home and Abroad. 关于顾问药剂师实践模式的说明:国内外。
Q2 Medicine Pub Date : 2024-11-01 DOI: 10.4140/TCP.n.2024.398
Chad Worz
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引用次数: 0
Pharmacist Innovators: Redefining Roles, Elevating Care, Making Their Mark. 药剂师创新者:重新定义角色,提升护理水平,创造自己的印记。
Q2 Medicine Pub Date : 2024-11-01 DOI: 10.4140/TCP.n.2024.432
Leigh Davitian
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引用次数: 0
How Should the Scope of Pharmacy Practice Be Decided? 应如何决定药学实践的范围?
Q2 Medicine Pub Date : 2024-11-01 DOI: 10.4140/TCP.n.2024.396
Chris Alderman
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引用次数: 0
Pharmacist Interventions for Inhaled Medication Use in Chronic Obstructive Pulmonary Disease (COPD). 药剂师对慢性阻塞性肺病 (COPD) 吸入药物使用的干预。
Q2 Medicine Pub Date : 2024-11-01 DOI: 10.4140/TCP.n.2024.417
Amanda Tam, Christian Nelson, Carla Bouwmeester

Pharmacists are ideally situated and trained to educate and advocate for the proper use of inhaled medications among patients in the community. Proper inhaler technique is an important way to prevent exacerbations and manage the symptoms associated with chronic pulmonary diseases. The American Lung Association estimates almost 6 million people 65 years of age or older had a diagnosis of chronic obstructive pulmonary disease (COPD) in 2020 in the United States. However, published reports have found that less than 20% of older people with COPD use inhalers correctly. As inhalers are the primary route of administration for medications used to treat chronic airway diseases such as COPD, pharmacist-led education can help overcome the widespread lack of knowledge regarding proper inhaler use.

药剂师在教育和倡导社区患者正确使用吸入药物方面处于理想的位置,并接受过相关培训。正确使用吸入器是预防病情恶化和控制慢性肺病相关症状的重要方法。据美国肺脏协会估计,2020 年美国将有近 600 万 65 岁或以上的人被诊断患有慢性阻塞性肺病 (COPD)。然而,已发表的报告发现,只有不到 20% 的慢性阻塞性肺病老年人能够正确使用吸入器。由于吸入器是治疗慢性阻塞性肺病等慢性气道疾病药物的主要给药途径,药剂师引导的教育有助于克服普遍缺乏正确使用吸入器知识的问题。
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引用次数: 0
Co-designing Medication Optimization Patient-Centered Outcomes Research With Older People and Caregivers as Research Partners. 以老年人和护理人员为研究伙伴,共同设计以患者为中心的用药优化成果研究。
Q2 Medicine Pub Date : 2024-11-01 DOI: 10.4140/TCP.n.2024.425
Eposi Elonge, Catherine E Cooke, Merton Lee, Viviane Tang, Jodi-Ann Haynes, Sabrina Wang, Andrew Genuit, Brian Isetts, Karen Pellegrin, Judy Mikami, Del Price, Nicole Brandt

Background: Additional evidence is required to address the unintended consequences of medication use in older people and the required caregiver support. To inform priorities for future research efforts, different stakeholder perspectives are needed, including those of older people, caregivers, clinicians, and researchers. Objective: To develop a co-designed medication-related research agenda. Methods: A 12-member Advisory Council, half of which were older people and caregivers, designed the research. An 11-question survey to identify priorities for medication-related patient-centered outcomes research (PCOR) topics was administered to members of the Elder Care Medicine Network (ECMN) (ie, older people, caregivers, clinicians, and researchers). Respondents were categorized into two groups with hierarchical assignment to the clinician/research group over the older adult/caregiver group. Chi-square tests compared priority areas for medication-related PCOR between the two groups. Results: There were 53 responses (48% response rate) from the ECMN, with 39.6% (n = 21) from the clinician/researcher group and 60.4% (n = 32) from the older adult/caregiver group. The priority areas from both groups included safe ways to simplify medicines (62.2%), communicating with pharmacists and prescribers about medications (58.5%), and information about safe supplements with prescription medications (52.8%). Statistically significant differences existed between the two groups in the proportions choosing the priority areas. Conclusion: Co-design of a survey to identify priority areas for PCOR demonstrated successful engagement of older people and caregivers as research partners. While older people and caregivers may have differing perspectives on the importance of specific medication-related PCOR topics, simplifying medication regimen and health care communications were germane to both groups.

背景:需要更多的证据来说明老年人用药的意外后果以及所需的护理人员支持。为了确定未来研究工作的重点,需要从不同利益相关者的角度出发,包括老年人、护理人员、临床医生和研究人员。目标:制定共同设计的药物相关研究议程。方法:由由 12 名成员组成的咨询委员会设计了研究议程,其中半数为老年人和护理人员。对老年护理医学网络 (ECMN) 的成员(即老年人、护理人员、临床医生和研究人员)进行了一项包含 11 个问题的调查,以确定与药物相关的以患者为中心的结果研究 (PCOR) 课题的优先次序。受访者被分为两组,临床医生/研究人员组的受访者比老年人/护理人员组的受访者多。通过卡方检验比较了两组受访者在药物相关 PCOR 方面的优先领域。结果:ECMN 共收到 53 份回复(回复率为 48%),其中 39.6%(n = 21)来自临床医生/研究人员组,60.4%(n = 32)来自老年人/护理人员组。两组优先考虑的领域都包括简化药物的安全方法(62.2%)、与药剂师和处方医生就药物问题进行沟通(58.5%)以及有关处方药安全补充剂的信息(52.8%)。在选择优先领域的比例上,两组之间存在明显的统计学差异。结论共同设计调查以确定 PCOR 的优先领域,表明老年人和护理人员作为研究伙伴的成功参与。虽然老年人和护理人员对具体的用药相关 PCOR 主题的重要性可能有不同的看法,但简化用药方案和医疗保健沟通对这两个群体来说都是至关重要的。
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引用次数: 0
Marsha Meyer PRESIDENT 2024-2025. 玛莎·梅耶2024-2025年总统。
Q2 Medicine Pub Date : 2024-11-01 DOI: 10.4140/TCP.n.2024.401
Eleanor Smith

President for the 2024-2025 year, Marsha Meyer sat down with ASCP's Director of Publications, Eleanor Smith, for an in-depth look at her career, her leadership style, and her plans for the association.

作为2024-2025年度的主席,玛莎·梅耶接受了ASCP出版总监埃莉诺·史密斯的采访,深入了解了她的职业生涯、她的领导风格以及她对协会的计划。
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引用次数: 0
Marsha Meyer PRESIDENT 2024-2025. 主席 2024-2025 年。
Q2 Medicine Pub Date : 2024-11-01 DOI: 10.4140/TCP.n.2024.401
Eleanor Smith
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Senior Care Pharmacist
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