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Success in Heart Failure? An Investigation of Heart Failure Readmission Rates and Medication Regimen Optimization. 心力衰竭成功了吗?对心衰再入院率和用药方案优化的调查。
Q2 Medicine Pub Date : 2024-03-01 DOI: 10.4140/TCP.n.2024.113
Dominic Bracken, Sarah Wagner-Dallas, Destiny Branum

In May 2022, the American College of Cardiology updated their guideline-directed medical therapy for congestive heart failure (CHF) to include four pillars of therapy. These pillars aim to better control patients with heart failure (HF) and reduce the incidence of hospitalization by including an evidence-based beta-blocker, an angiotensin-converting enzyme inhibitor/ angiotensin receptor blocker/angiotensin receptor/ neprilysin inhibitor, a mineralocorticoid receptor antagonist, and newly recommended sodium glucose cotransporter 2-inhibitors. This study at University of Florida Health Central Florida Hospitals reviewed patients who were diagnosed with CHF and recorded if they were readmitted with a HF exacerbation within 30 days of an initial index admission. Patients had data obtained retrospectively using electronic medical records from patient hospital encounters within the study inclusion dates; 7/1/2022-9/30/2022. Hospital readmission rates for patients with CHF, and information on each patient's medication regimen was collected to see if they met medication optimization criteria. A total of 252 patients were evaluated, with 157 meeting the inclusion criteria. Of the patients included, 23 (14.6%) experienced a hospital readmission within 30 days because of acute HF exacerbation or worsening HF. After reviewing medication regimens, 60 patients (38.2%) were receiving treatment with one pillar of therapy, 72 (45.8%) with two pillars of therapy, 12 (7.6%) with three pillars of therapy, and one patient was treated with all four pillars of therapy. In conclusion, this study showed that the recommended pillars of therapy are not being implemented and patients with CHF may benefit from medication optimization.

2022 年 5 月,美国心脏病学会更新了充血性心力衰竭(CHF)的指南指导疗法,增加了四大治疗支柱。这些支柱旨在通过循证β受体阻滞剂、血管紧张素转换酶抑制剂/血管紧张素受体阻滞剂/血管紧张素受体/肾素抑制剂、矿物质皮质激素受体拮抗剂以及新推荐的钠葡萄糖共转运体 2 抑制剂,更好地控制心力衰竭(HF)患者的病情,降低住院率。佛罗里达大学健康中心佛罗里达医院的这项研究对确诊为慢性心力衰竭的患者进行了回顾性研究,并记录了他们在首次入院后30天内是否因心力衰竭加重而再次入院。患者的数据是在研究纳入日期(7/1/2022-9/30/2022)内使用电子病历从医院获得的。研究人员收集了慢性阻塞性肺病患者的再入院率以及每位患者的用药方案信息,以确定他们是否符合用药优化标准。共对 252 名患者进行了评估,其中 157 人符合纳入标准。在纳入的患者中,有 23 人(14.6%)因急性心房颤动加重或心房颤动恶化而在 30 天内再次入院。在检查了药物治疗方案后,60 名患者(38.2%)接受了一种支柱疗法的治疗,72 名患者(45.8%)接受了两种支柱疗法的治疗,12 名患者(7.6%)接受了三种支柱疗法的治疗,1 名患者接受了所有四种支柱疗法的治疗。总之,这项研究表明,推荐的支柱疗法并未得到实施,慢性阻塞性肺病患者可能会从优化药物治疗中获益。
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引用次数: 0
The Use of Antipsychotics in Long-term Care: A Complicated Relationship. 长期护理中抗精神病药物的使用:复杂的关系。
Q2 Medicine Pub Date : 2024-03-01 DOI: 10.4140/TCP.n.2024.95
Rob Leffler
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引用次数: 0
Bereavement and Loss: Understanding Grief in Older People. 丧亲之痛与损失:了解老年人的悲痛。
Q2 Medicine Pub Date : 2024-03-01 DOI: 10.4140/TCP.n.2024.98
Kirsten Werner, Jeannette Y Wick

Everyone experiences grief from time to time, but older people are more likely to experience grief simply because they live longer. Grief, bereavement, and mourning are different elements associated with death of a loved one. For most people, grief follows a fairly predictable trajectory, and over time resolves. One of the most used descriptions of grief was developed by Elizabeth Kubler-Ross and it is reviewed herein. However, for some people, grief becomes unbearable and chronic leading to prolonged grief disorder. For clinicians, it's essential to differentiate between prolonged grief disorder and major depressive disorder. Older people who experience unbearable grief often need medication to deal with some of its symptoms, which include depression, anxiety, hypertension, and lack of sleep. Older people also need considerable support as they deal with grief so that they do not become isolated, experience comorbidities, or spiral into physical and mental decline. Little specific research has examined pharmacists' opportunities to help older people who have prolonged grief, but some data suggest that these patients are more likely to visit the pharmacy and need medication more than others.

每个人都会时不时地经历悲伤,但老年人更容易经历悲伤,原因很简单,因为他们活得更长。悲伤、丧亲之痛和哀悼是与亲人死亡相关的不同因素。对大多数人来说,悲伤会遵循一个相当可预测的轨迹,并随着时间的推移而消退。伊丽莎白-库伯勒-罗斯(Elizabeth Kubler-Ross)对悲伤进行了最常用的描述,本文将对其进行回顾。然而,对于某些人来说,悲伤会变得难以忍受并长期存在,从而导致长期悲伤障碍。对于临床医生来说,必须区分长期悲伤障碍和重度抑郁障碍。经历过难以忍受的悲伤的老年人通常需要药物来应对一些症状,包括抑郁、焦虑、高血压和睡眠不足。老年人在面对悲伤时也需要大量的支持,这样他们才不会变得孤立无援、出现合并症或身体和精神衰退。药剂师帮助长期悲伤的老年人的机会很少有具体的研究,但一些数据表明,这些病人比其他人更有可能去药房,也更需要药物。
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引用次数: 0
Telehealth and Pharmaceutical Care for Older People: Today and Tomorrow. 老年人的远程保健和药物治疗:今天和明天。
Q2 Medicine Pub Date : 2024-03-01 DOI: 10.4140/TCP.n.2024.93
Chris Alderman
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引用次数: 0
Association of Pre-Pandemic Telehealth With Emergency Department and Telehealth Usage During the Pandemic. 大流行前远程医疗与大流行期间急诊科和远程医疗使用情况的关联。
Q2 Medicine Pub Date : 2024-03-01 DOI: 10.4140/TCP.n.2024.105
Michael Strand, Jonathan H Watanabe

Objectives Aims were to quantify the association of pre-COVID-19 pandemic telehealth use and separately: 1) likelihood of an emergency department (ED) visit, 2) likelihood of a telehealth visit in older people during the pandemic. Design A retrospective cohort study to measure odds ratios (ORs) of telehealth usage before the pandemic and likelihood of an ED visit and telehealth visit during the study period. Setting and Patients Adults 65 years of age and older (N = 39,214) in the University of California COVID Research Data Set (UC CORDS). Main Outcomes Primary outcome was occurrence of one or more ED visits. Secondary outcome was occurrence of one or more telehealth visits. Results A telehealth visit before the pandemic was associated with reduced likelihood of an ED visit with an OR of 0.33 (95% confidence interval [CI] 0.200.55). Pre-pandemic telehealth was associated with an increased likelihood of telehealth use during the pandemic with an OR of 4.66 (95% CI 3.52-6.18). Conclusion Older people who utilized telehealth before the pandemic were less likely to receive emergency care and were more likely to use telehealth during the pandemic. Approaches to enhance and measure telehealth access for older people are necessary.

目的 分别量化 COVID-19 大流行前远程医疗的使用与以下方面的关系1)急诊科(ED)就诊的可能性;2)大流行期间老年人远程保健就诊的可能性。设计 一项回顾性队列研究,测量大流行前使用远程保健的几率比(ORs)以及研究期间急诊室就诊和远程保健就诊的可能性。研究地点和患者 加州大学 COVID 研究数据集 (UC CORDS) 中 65 岁及以上的成年人(N = 39,214 人)。主要结果 主要结果是出现一次或多次急诊就诊。次要结果为一次或多次远程医疗就诊。结果 大流行前的远程保健就诊与减少急诊就诊的可能性相关,OR 值为 0.33(95% 置信区间 [CI] 0.200.55)。大流行前的远程保健与大流行期间使用远程保健的可能性增加有关,OR 值为 4.66(95% 置信区间 [CI] 3.52-6.18)。结论 在大流行前使用远程保健的老年人接受紧急护理的可能性较低,而在大流行期间使用远程保健的可能性较高。有必要采取一些方法来加强和衡量老年人使用远程保健的情况。
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引用次数: 0
Antipsychotics: Past, Present, and Future (Part 2): Article 2 of 3. 抗精神病药物:抗精神病药物:过去、现在和未来(第 2 部分):第 2 条,共 3 条。
Q2 Medicine Pub Date : 2024-02-01 DOI: 10.4140/TCP.n.2024.57
Steven Levenson

The history of antipsychotics in nursing facilities is one piece of a much larger, more complex puzzle. In many ways, it reflects the virtues and limitations of the entire health care system and those who provide care. None of the issues related to the use of antipsychotics are specific to these medications or to nursing facilities. After decades of effort to reduce unwarranted antipsychotics use, the current situation is still a work in progress. Many widely held assumptions and standard narratives, such as those about behavior, the place of medications in person-centered care, and the causes of inappropriate medication use are only partially correct. This second of three articles is not intended to discuss how to diagnose and manage behavior disorders or choose medications. Instead, it addresses the diverse perspectives and key players that have been involved and the results of their efforts. Ultimately, this will set the stage for specific recommendations (part 3) about learning from past efforts surrounding antipsychotics to identify more definitive and lasting improvements in the future. Part 1 of this series covered the history of attempts to influence use of medications-especially, antipsychotics-in nursing facility care of residents with behavior, mood, and cognitive issues. These improvement efforts can be described as fragmented, often ineffectual, and politically fraught. After decades of effort, and despite a significant reduction in the indiscriminate use of antipsychotics, psychotropics are still widely used in nursing facilities.1 The extent of improvement overall in managing individuals with dementia and other diverse behavior, mood, and cognitive issues is unclear.

护理机构使用抗精神病药物的历史是一个更大、更复杂的谜团中的一个片段。在许多方面,它反映了整个医疗保健系统和提供护理者的优点和局限性。与使用抗精神病药物相关的问题都不是这些药物或护理机构所特有的。经过数十年减少抗精神病药物不当使用的努力,目前的状况仍在不断改进中。许多广为流传的假设和标准说法,如关于行为、药物在以人为本的护理中的地位以及不当用药的原因等,只有部分是正确的。本文是三篇文章中的第二篇,无意讨论如何诊断和管理行为障碍或选择药物。相反,这篇文章将讨论不同的观点、参与其中的关键人物以及他们的努力成果。最终,这将为具体建议(第三部分)奠定基础,即从过去围绕抗精神病药物所做的努力中吸取经验教训,以确定未来更明确、更持久的改进措施。本系列的第 1 部分介绍了护理机构在护理有行为、情绪和认知问题的住院患者时,试图影响药物(尤其是抗精神病药物)使用的历史。这些改进工作可以说是支离破碎,往往效果不佳,而且充满政治色彩。经过数十年的努力,尽管抗精神病药物的滥用已显著减少,但精神药物仍在护理机构中广泛使用。1 在管理痴呆症患者及其他各种行为、情绪和认知问题方面的整体改善程度尚不明确。
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引用次数: 0
Providing Balanced Hope and Realism for Patients and Families. 为患者和家属提供希望与现实的平衡。
Q2 Medicine Pub Date : 2024-02-01 DOI: 10.4140/TCP.n.2024.50
Chris Alderman
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引用次数: 0
Impact of a Virtual Game, 'Name That Band,' on Older People's and PharmD Students' Feelings of Social Isolation During COVID-19. 在 COVID-19 期间,虚拟游戏 "乐队名称 "对老年人和药学博士生社交孤立感的影响。
Q2 Medicine Pub Date : 2024-01-01 DOI: 10.4140/TCP.n.2024.22
Alison M Weygint, Brooke T Whittington, Jeannie K Lee, Ashley M Campbell

Background Prior to the COVID-19 pandemic, PharmD students at the University of Arizona (UArizona) had a long-standing relationship with the older people at St. Luke's Home, a local Eden Alternative assisted-living community. Hosting community engagement programs for assisted-living residents was challenging with COVID-19 precautions and older individuals suffering from social isolation and loneliness. Objective To determine the impact of playing a virtual game, 'Name That Band,' on older people's and PharmD students' feelings of social isolation during the COVID-19 pandemic. Methods Questionnaires were administered before and after a virtual game to residents at St. Luke's Home and PharmD students at UArizona. Participants were asked about their mood before COVID-19 and pre-and postgame, as well as their social interactions and feelings of loneliness using the Modified UCLA Three-Item Loneliness Scale, which assesses a composite score of lack of companionship, feelings of being left out, and isolation. Results Fifteen older people and 11 students participated in the game (N = 26). All participants completed the pregame survey and 25 completed the postgame survey. The older people reported fewer feelings of isolation and loneliness (measured by a reduction in UCLA Loneliness Scale score) postgame compared with pregame. The students reported a higher total UCLA Loneliness Scale score during the pandemic than prepandemic, but there was no difference in their scores postgame compared with pregame. More older people and students reported feeling 'happy' after playing the virtual game together compared with before the pandemic and before playing. The aspect of the activity that helped older people and students feel more socially engaged was playing a game. Conclusion A social intervention using a virtual game may be a tool that can be used to decrease feelings of isolation and increase engagement for older people residing in an assisted-living community.

背景 在 COVID-19 大流行之前,亚利桑那大学 (UArizona) 的药剂学博士生与当地伊甸园替代性辅助生活社区 St.由于 COVID-19 的预防措施以及老年人遭受社会隔离和孤独的困扰,为协助生活的居民举办社区参与计划具有挑战性。目标 确定在 COVID-19 大流行期间,玩虚拟游戏 "说出那个乐队的名字 "对老年人和药学博士生的社会隔离感的影响。方法 在虚拟游戏前后对圣路加养老院的居民和亚利桑那大学的药学博士生进行问卷调查。问卷调查了参与者在 COVID-19 之前和游戏前后的情绪,以及他们的社交互动和孤独感,采用的是修改后的 UCLA 孤独感三项目量表,该量表评估了缺乏陪伴、被冷落感和孤独感的综合得分。结果 15 名老年人和 11 名学生参加了游戏(N = 26)。所有参与者都完成了赛前调查,25 人完成了赛后调查。与赛前相比,赛后老年人报告的孤独感和孤立感减少了(以加州大学洛杉矶分校孤独感量表得分的减少来衡量)。学生在大流行期间的 UCLA 孤独感量表总分高于大流行前,但他们在大流行后的得分与大流行前相比没有差异。与大流行前和游戏前相比,更多的老年人和学生表示在一起玩虚拟游戏后感到 "快乐"。活动中让老年人和学生感觉更有社会参与感的方面是玩游戏。结论 利用虚拟游戏进行社交干预可能是一种工具,可用来减少居住在辅助生活社区的老年人的孤独感并提高他们的参与度。
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引用次数: 0
Patient Attitudes Toward Deprescribing Among Community-Dwelling Older Mainers. 在社区居住的老年缅因人中,病人对开药的态度。
Q2 Medicine Pub Date : 2024-01-01 DOI: 10.4140/TCP.n.2024.30
Joshua Carver, Sydney P Springer

Background The excess use of medications has become an increasingly prevalent issue in health care. Deprescribing can be an important tool in combating polypharmacy. Objective To assess the attitudes of community-dwelling older persons in Maine toward their medications and the concept of deprescription. An additional aim of this research was to assess the association between the revised Patient Attitudes Toward Deprescribing Questionnaire (rPATDQ) domains by polypharmacy status. Methods Researchers conducted a cross-sectional study utilizing the rPATDQ. Authors recruited older Mainers via a longitudinal cohort study through the University of New England Center for Excellence in Aging in Health. Respondents were stratified by polypharmacy status (fewer than five medications, five or more medications). Results Total daily medications ranged from 1 to 30 (average of 8.6). Overall, 83.6% of respondents agreed/strongly agreed to the statement "If my doctor said it was possible, I would be willing to stop one or more of my regular medicines." 70.6% agreed/ strongly agreed to the statement "Overall, I am satisfied with my current medicines." Those with and without polypharmacy experienced low overall medication burden and a high belief in the appropriateness of their medications. There were no statistically significant differences between polypharmacy groups. Conclusion The results of this survey indicate that the factors affecting attitudes toward deprescribing are complex. While many indicated willingness to deprescribe at least one medication, there was a high degree of satisfaction with current medication regimens. This study highlights the need for further qualitative research to identify potential barriers to deprescribing.

背景 过度用药已成为医疗保健领域日益普遍的问题。去处方化可能是对抗多药滥用的一个重要工具。目标 评估缅因州社区老年人对药物的态度以及去处方化的概念。本研究的另一个目的是评估修订后的 "患者对去处方化的态度调查问卷"(rPATDQ)各领域与多重用药状况之间的关联。方法 研究人员利用 rPATDQ 进行了一项横断面研究。作者通过新英格兰大学健康老龄化卓越中心的一项纵向队列研究招募了缅因州的老年人。根据多药状态(少于五种药物、五种或五种以上药物)对受访者进行了分层。结果 每天服用的药物总量从 1 种到 30 种不等(平均为 8.6 种)。总体而言,83.6% 的受访者同意/非常同意 "如果医生说有可能,我愿意停用一种或多种常规药物 "这一说法。70.6%的受访者同意/非常同意 "总体而言,我对目前的药物感到满意"。使用多种药物和未使用多种药物的患者的总体用药负担较轻,并且非常相信药物的适当性。多药治疗组之间在统计学上没有明显差异。结论 本次调查的结果表明,影响人们对去处方化态度的因素非常复杂。虽然许多人表示愿意取消至少一种药物的处方,但他们对目前的用药方案非常满意。这项研究强调了进一步开展定性研究的必要性,以确定取消处方的潜在障碍。
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引用次数: 0
Beyond Drug Facts: The Vital Role of Soft Skills in Senior Care Pharmacy Education. 超越药物事实:软技能在老年护理药学教育中的重要作用。
Q2 Medicine Pub Date : 2024-01-01 DOI: 10.4140/TCP.n.2024.3
Dawn Gerber
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引用次数: 0
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Senior Care Pharmacist
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