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Geriatric Pharmacotherapy Case Series: Secondary Stroke Prevention in Older People. 老年药物治疗案例系列:老年人的二级卒中预防。
Q2 Medicine Pub Date : 2025-09-01 DOI: 10.4140/TCP.n.2025.347
Elizabeth K Pogge

This case highlights the pharmacist's role in the outpatient management of an older patient with complex cardiovascular conditions following a stroke. The patient lives in the community and is seen in a pharmacist-run clinic for chronic disease state management. The focus is on secondary stroke prevention through lifestyle modifications and optimization of comorbid conditions, including smoking cessation, antithrombotic therapy, and management of hyperlipidemia, hypertension, and diabetes.

这个案例强调了药剂师在老年患者中风后复杂心血管疾病的门诊管理中的作用。患者住在社区,并在药剂师经营的慢性疾病状态管理诊所就诊。重点是通过改变生活方式和优化合并症来预防继发性卒中,包括戒烟、抗血栓治疗、高脂血症、高血压和糖尿病的管理。
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引用次数: 0
Congress May Have Stalled Out, But States Are Taking on the PBMs. 国会可能已经停滞不前,但各州正在采取pbm。
Q2 Medicine Pub Date : 2025-09-01 DOI: 10.4140/TCP.n.2025.373
Leigh Davitian
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引用次数: 0
An Age-Friendly Approach to Medication Optimization. 对老年人友好的药物优化方法。
Q2 Medicine Pub Date : 2025-09-01 DOI: 10.4140/TCP.n.2025.340
Joshua Chou, Stephen Orion Courtin

This is the second in a series of Age-Friendly case studies developed as a function of the John A. Hartford Foundation grant to the American Society of Consultant Pharmacists and the Peter Lamy Center on Drug Therapy and Aging at the University of Maryland School of Pharmacy to Leverage Pharmacists as Age-Friendly 4Ms Champions. This series presents a case for each of the 4Ms: What Matters, Medication, Mentation, and Mobility, and examines how these elements interrelate to optimize care for older patients.This case presents an interprofessional framework for optimizing a patient's medication regimen. It includes tools and suggested deprescribing guidelines to help pharmacists prioritize medication recommendations. Using the Age-Friendly 4Ms framework, the authors reviewed and adjusted the patient's medications, aiming to support her "What Matters" goal of returning to volunteer work at her church, which she had given up because of unsteadiness, low energy, and difficulty focusing. The care team developed a plan involving interprofessional collaboration among a social worker, physical therapist, primary care provider, and to support the patient in reaching her goal.

这是约翰·哈特福德基金会向美国咨询药剂师协会和马里兰大学药学院的彼得·拉米药物治疗和衰老中心提供的一系列“老年友好型”案例研究中的第二个,这些研究旨在利用药剂师作为老年友好型4位女士的冠军。本系列介绍了4Ms中的每一个案例:重要的是什么,药物,心理状态和活动,并研究了这些元素如何相互关联以优化老年患者的护理。本案例提出了优化患者药物治疗方案的跨专业框架。它包括工具和建议的处方指南,以帮助药剂师优先考虑药物建议。使用年龄友好型4Ms框架,作者审查并调整了患者的药物,旨在支持她“什么重要”的目标,即回到她的教堂做志愿者工作,她因为不稳定、精力不足和难以集中注意力而放弃了这项工作。护理团队制定了一个计划,包括社会工作者、物理治疗师、初级保健提供者之间的跨专业合作,并支持患者实现目标。
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引用次数: 0
Congress Delivers One Big Beautiful Bill-But What Was Left on the Cutting Room Floor? 国会提交了一项宏伟的法案,但剪掉的地板上还剩下什么?
Q2 Medicine Pub Date : 2025-08-01 DOI: 10.4140/TCP.n.2025.334
Leigh Davitian
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引用次数: 0
Creation of a Peri- and Post- operative Care Rotation for a Geriatric Pharmacy Residency: A Pilot Experience. 创建围手术期和术后护理轮转老年药房住院医师:试点经验。
Q2 Medicine Pub Date : 2025-08-01 DOI: 10.4140/TCP.n.2025.320
Gabriela Alvarez, Arielle J Hopkins, Andras Farkas

Pharmacists have emerged as important members of the health care team to optimize outcomes for older patients. Demand for pharmacists with experience caring for adults aged 65 years and older is expected to increase as the population continues to age. Cooperman Barnabas Medical Center (CBMC) is an acute care hospital located in Livingston, New Jersey, that offers a Post-Graduate Year-2 (PGY2) Geriatric Pharmacy Residency Program. The hospital performs a variety of surgical services for many older patients annually. The authors aimed to outline a residency rotation developed within this program that was designed to introduce the resident to the peri- and post-operative setting. Over a four-week period, the resident identified 70 opportunities to optimize medication use in surgical and postoperative older patients. Of these recommendations, 70% were accepted, indicating potential value to the health care team. Creating this rotation enabled the residency program to achieve its goal of developing a specialized clinician to serve the medical needs of older patients.

药剂师已经成为医疗保健团队的重要成员,以优化老年患者的结果。随着人口持续老龄化,对具有照顾65岁及以上成年人经验的药剂师的需求预计将增加。库伯曼巴纳巴斯医疗中心(CBMC)是一家位于新泽西州利文斯顿的急症护理医院,提供研究生二年级(PGY2)老年药学住院医师项目。这家医院每年为许多老年病人进行各种外科手术。作者旨在概述在该项目中发展的住院医师轮转,旨在向住院医师介绍围手术期和术后环境。在四周的时间里,住院医师确定了70个优化手术和术后老年患者药物使用的机会。在这些建议中,70%被接受,这表明对卫生保健团队的潜在价值。创造这种轮转使住院医师计划实现了培养专业临床医生以满足老年患者医疗需求的目标。
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引用次数: 0
2025 New Drug Update: Recent Approvals and Their Clinical Implications. 2025新药更新:最近的批准及其临床意义。
Q2 Medicine Pub Date : 2025-08-01 DOI: 10.4140/TCP.n.2025.306
Kasper Lee, Nadia Khartabil

With the increasing prevalence of polypharmacy, age-related physiological changes, and the need for individualized pharmacotherapy in older patients, understanding new drug approvals is crucial to optimizing medication management. This paper synthesizes the latest evidence and offers insights into prescribing considerations, potential drug-drug interactions, and strategies to mitigate adverse effects. We believe this work will be of significant interest to health care professionals, including pharmacists, physicians, and geriatric specialists, as they navigate the evolving landscape of pharmacotherapy in older adults.

随着多种药物的日益流行,年龄相关的生理变化,以及老年患者对个性化药物治疗的需求,了解新药批准对于优化药物管理至关重要。本文综合了最新的证据,并提供了有关处方考虑因素,潜在的药物-药物相互作用以及减轻不良反应的策略的见解。我们相信这项工作将对包括药剂师、医生和老年医学专家在内的卫生保健专业人员产生重大的兴趣,因为他们正在研究老年人药物治疗的发展前景。
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引用次数: 0
Community Pharmacy Opioid Risk Screening Assessments: Comparing older adults (65+) to those under 65. 社区药房阿片类药物风险筛查评估:比较老年人(65岁以上)和65岁以下的人。
Q2 Medicine Pub Date : 2025-08-01 DOI: 10.4140/TCP.n.2025.325
Oliver Frenzel, Jayne Steig, Elizabell Delgado, Heidi Eukel

Background Older adults are at increased risk for opioid-related harm due to decreased drug metabolism and elimination, polypharmacy, and comorbid conditions. The ONE (Opioid and Naloxone Education) Program is a pharmacy-based opioid risk mitigation initiative that employs evidence-based patient screening to identify risk of opioid-use-disorder (OUD) and opioid overdose (OD). Based on screening results, pharmacists provide patient-specific education and interventions. Objective To compare the risk of OUD, OD, and the opioid harm reduction interventions provided to adults aged 65 and older to those under 65 recieving opioid medications. Design The screening tool used in this study is a paper-based, patient-facing instrument intended to be completed by the patient. Pharmacists recommend patients to complete the screening tool and participate when presenting an opioid prescription to be filled. However, completing the screening tool is voluntary for the patient. Setting The ONE Program invited all registered pharmacists in the state to participate in a free three-hour continuing education (CE) program, offered live or online. The training consisted of education including but not limited to risks associated with opioids and accidental overdose, the role of naloxone, and the use and interpretation of the opioid risk screening tool. The program began in 2018 in North Dakota and now spans over 75 community pharmacies across the state. Methods Patient demographics, opioid risk screening results, and pharmacist-delivered interventions were analyzed from 2022 to 2023. Statistical analysis and age stratification were conducted on 15,025 screenings to evaluate OUD risk, OD risk, and delivered interventions. The North Dakota State University Institutional Review Board approved the methods and research design of this study (IRB0003838). Results Patients aged 65 and older had a 36% higher risk of OD, while those under 65 had a 51% higher risk of developing OUD. The older age group received a statistically significant higher proportion of naloxone education and dispensed naloxone from the pharmacy. Concurrent use of benzodiazepines and muscle-relaxants was significantly higher in the younger age group; however, the 65 and older age group reported taking multiple opioids nearly twice as frequently as those under 65. Conclusion A comparison of opioid use, opioid risk stratification, and interventions for patients under 65 and 65 and older showed statistically significant findings. Community pharmacy-based opioid risk screening offers an innovative approach to identifying high-risk patients and delivering tailored interventions directed to opioid-harm reduction.

背景:由于药物代谢和消除减少、多药和合并症,老年人发生阿片类药物相关伤害的风险增加。ONE(阿片类药物和纳洛酮教育)项目是一项基于药物的阿片类药物风险缓解倡议,采用循证患者筛查来识别阿片类药物使用障碍(OUD)和阿片类药物过量(OD)的风险。根据筛查结果,药剂师提供针对患者的教育和干预措施。目的比较65岁及以上成年人与65岁以下接受阿片类药物治疗的成年人发生OUD、OD的风险以及阿片类药物减少危害的干预措施。本研究中使用的筛查工具是一种纸质的、面向患者的仪器,由患者完成。药剂师建议患者完成筛查工具,并在提交阿片类药物处方时参与。然而,完成筛查工具是患者自愿的。ONE计划邀请该州所有注册药剂师参加一个免费的三小时继续教育(CE)计划,提供现场或在线服务。培训包括教育,包括但不限于与阿片类药物和意外过量相关的风险,纳洛酮的作用,以及阿片类药物风险筛查工具的使用和解释。该项目于2018年在北达科他州启动,目前已覆盖全州75多家社区药店。方法分析2022 - 2023年患者人口统计学、阿片类药物风险筛查结果和药剂师提供的干预措施。对15025例筛查进行统计分析和年龄分层,以评估OUD风险、OD风险和交付的干预措施。北达科他州立大学机构审查委员会批准了本研究的方法和研究设计(IRB0003838)。结果65岁及以上患者发生OD的风险增加36%,65岁以下患者发生OUD的风险增加51%。老年组接受纳洛酮教育的比例和从药房配药纳洛酮的比例有统计学意义。同时使用苯二氮卓类药物和肌肉松弛剂在年轻年龄组中明显更高;然而,65岁及以上年龄组报告服用多种阿片类药物的频率几乎是65岁以下人群的两倍。结论对65岁以下和65岁及以上患者的阿片类药物使用、阿片类药物风险分层和干预措施进行比较,结果具有统计学意义。以社区药房为基础的阿片类药物风险筛查提供了一种创新方法,可识别高风险患者并提供针对性的干预措施,以减少阿片类药物的危害。
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引用次数: 0
Geriatric Pharmacotherapy Case Series: Polypharmacy Leading to Acute Kidney Injury. 老年药物治疗案例系列:多种药物导致急性肾损伤。
Q2 Medicine Pub Date : 2025-08-01 DOI: 10.4140/TCP.n.2025.315
Jelena Lewis, Laura Tsu, Fatema Haider

This case study focuses on the treatment of a patient who develops acute kidney injury due to multiple medications used to treat her comorbidities. Older people are at higher risk of developing acute kidney injury compared to the general adult population and are also at the highest risk of morbidity and mortality from this disease state. This case reviews the approach of assessing and adjusting therapy in an older patient and the common etiologies of acute kidney injury.

本案例研究的重点是治疗一名因多种药物治疗其合并症而发生急性肾损伤的患者。与一般成年人相比,老年人发生急性肾损伤的风险更高,并且这种疾病状态的发病率和死亡率也最高。本病例回顾了评估和调整治疗的方法在老年患者和常见的病因急性肾损伤。
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引用次数: 0
Gratitude for Older Research Participants. 感谢年长的研究参与者。
Q2 Medicine Pub Date : 2025-08-01 DOI: 10.4140/TCP.n.2025.304
Demetra Antimisiaris, Patricia W Slattum
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引用次数: 0
The Silent Surge: Are We Facing the Chronic Disease Epidemic "Head-On"? 无声的浪潮:我们是否正“正面”面对慢性疾病的流行?
Q2 Medicine Pub Date : 2025-07-01 DOI: 10.4140/TCP.n.2025.299
Leigh Davitian
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引用次数: 0
期刊
Senior Care Pharmacist
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