Abstract In recent years, journals have increasingly become a research topic in their own right. Trying to avoid the rigid functional definitions of journals (periodicity, publicity, etc.), it is a major challenge at the moment for literary studies to come up with a new and more appropriate way of thinking about the subject. This paper contributes to this endeavour by proposing to think about journals not as fixed items but as relational objects that not only have an impact on the texts but are affected by them as well. Thus, it suggests not to talk about journals and texts individually but to recognize the specific media formatting that they form together.
{"title":"Zeitschriften als Medienformatierung","authors":"Daniel Ehrmann","doi":"10.1515/iasl-2022-0014","DOIUrl":"https://doi.org/10.1515/iasl-2022-0014","url":null,"abstract":"Abstract In recent years, journals have increasingly become a research topic in their own right. Trying to avoid the rigid functional definitions of journals (periodicity, publicity, etc.), it is a major challenge at the moment for literary studies to come up with a new and more appropriate way of thinking about the subject. This paper contributes to this endeavour by proposing to think about journals not as fixed items but as relational objects that not only have an impact on the texts but are affected by them as well. Thus, it suggests not to talk about journals and texts individually but to recognize the specific media formatting that they form together.","PeriodicalId":42506,"journal":{"name":"INTERNATIONALES ARCHIV FUR SOZIALGESCHICHTE DER DEUTSCHEN LITERATUR","volume":"47 1","pages":"285 - 337"},"PeriodicalIF":0.2,"publicationDate":"2022-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48380700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"文学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abstract The article examines a genre of popular literature that accompanied the build-up of the German navy in the 1880 s and 1890 s. This Marineliteratur produced seminal images and narratives closely related to political naval and colonial discourses of the Deutsches Kaiserreich. The proponents of a national navy were then able to draw upon the wealth of these “naval fantasies” for their own propaganda. By appealing to a broad audience, but especially to young bourgeois men, the literary genre problematically partakes in shaping and popularizing national, imperial, and masculine identities.
{"title":"„Deutschland zur See“","authors":"Christian O. Schmitt","doi":"10.1515/iasl-2022-0017","DOIUrl":"https://doi.org/10.1515/iasl-2022-0017","url":null,"abstract":"Abstract The article examines a genre of popular literature that accompanied the build-up of the German navy in the 1880 s and 1890 s. This Marineliteratur produced seminal images and narratives closely related to political naval and colonial discourses of the Deutsches Kaiserreich. The proponents of a national navy were then able to draw upon the wealth of these “naval fantasies” for their own propaganda. By appealing to a broad audience, but especially to young bourgeois men, the literary genre problematically partakes in shaping and popularizing national, imperial, and masculine identities.","PeriodicalId":42506,"journal":{"name":"INTERNATIONALES ARCHIV FUR SOZIALGESCHICHTE DER DEUTSCHEN LITERATUR","volume":"47 1","pages":"549 - 578"},"PeriodicalIF":0.2,"publicationDate":"2022-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43526164","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"文学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Maria Luisa Romero, Hector Garcia Seisdedos, Beatriz Ibarra-Molero
The stabilization of natural proteins is a long-standing desired goal in protein engineering. Optimizing the hydrophobicity of the protein core often results in extensive stability enhancements. However, the presence of totally or partially buried catalytic charged residues, essential for protein function, has limited the applicability of this strategy. Here, focusing on the thioredoxin, we aimed to augment protein stability by removing buried charged residues in the active site without loss of catalytic activity. To this end, we performed a charged-to-hydrophobic substitution of a buried and functional group, resulting in a significant stability increase yet abolishing catalytic activity. Then, to simulate the catalytic role of the buried ionizable group, we designed a combinatorial library of variants targeting a set of seven surface residues adjacent to the active site. Notably, more than 50% of the library variants restored, to some extent, the catalytic activity. The combination of experimental study of 2% of the library with the prediction of the whole mutational space by partial least squares regression revealed that a single point mutation at the protein surface is sufficient to fully restore the catalytic activity without thermostability cost. As a result, we engineered one of the highest thermal stabilities reported for a protein with a natural occurring fold (137°C). Further, our hyperstable variant preserves the catalytic activity both in vitro and in vivo.
{"title":"Active site center redesign increases protein stability preserving catalysis in thioredoxin.","authors":"Maria Luisa Romero, Hector Garcia Seisdedos, Beatriz Ibarra-Molero","doi":"10.1002/pro.4417","DOIUrl":"10.1002/pro.4417","url":null,"abstract":"<p><p>The stabilization of natural proteins is a long-standing desired goal in protein engineering. Optimizing the hydrophobicity of the protein core often results in extensive stability enhancements. However, the presence of totally or partially buried catalytic charged residues, essential for protein function, has limited the applicability of this strategy. Here, focusing on the thioredoxin, we aimed to augment protein stability by removing buried charged residues in the active site without loss of catalytic activity. To this end, we performed a charged-to-hydrophobic substitution of a buried and functional group, resulting in a significant stability increase yet abolishing catalytic activity. Then, to simulate the catalytic role of the buried ionizable group, we designed a combinatorial library of variants targeting a set of seven surface residues adjacent to the active site. Notably, more than 50% of the library variants restored, to some extent, the catalytic activity. The combination of experimental study of 2% of the library with the prediction of the whole mutational space by partial least squares regression revealed that a single point mutation at the protein surface is sufficient to fully restore the catalytic activity without thermostability cost. As a result, we engineered one of the highest thermal stabilities reported for a protein with a natural occurring fold (137°C). Further, our hyperstable variant preserves the catalytic activity both in vitro and in vivo.</p>","PeriodicalId":42506,"journal":{"name":"INTERNATIONALES ARCHIV FUR SOZIALGESCHICHTE DER DEUTSCHEN LITERATUR","volume":"19 1","pages":"e4417"},"PeriodicalIF":4.5,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9601870/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89051167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"文学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abstract The article investigates the role metaphors of optical media and projection have played within the conceptual and literary history of ideology. Starting with the figure of the camera obscura in Marx, Fontane, and other contemporaries, it is shown that the ambiguous concept of Lichtbild (slide, photography) gains significance in social thought and literature as a metaphor for false perception. Subsequently, the analysis of Theodor Fontane’s novel Effi Briest (1895) shows how optical media are turned into figures of narration that generate a critical perspective on bourgeois ideology and its affect structure.
{"title":"Lichtbilder der Ideologie: Von Marx zu Fontane","authors":"Till Breyer","doi":"10.1515/iasl-2022-0008","DOIUrl":"https://doi.org/10.1515/iasl-2022-0008","url":null,"abstract":"Abstract The article investigates the role metaphors of optical media and projection have played within the conceptual and literary history of ideology. Starting with the figure of the camera obscura in Marx, Fontane, and other contemporaries, it is shown that the ambiguous concept of Lichtbild (slide, photography) gains significance in social thought and literature as a metaphor for false perception. Subsequently, the analysis of Theodor Fontane’s novel Effi Briest (1895) shows how optical media are turned into figures of narration that generate a critical perspective on bourgeois ideology and its affect structure.","PeriodicalId":42506,"journal":{"name":"INTERNATIONALES ARCHIV FUR SOZIALGESCHICHTE DER DEUTSCHEN LITERATUR","volume":"47 1","pages":"131 - 155"},"PeriodicalIF":0.2,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48172152","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"文学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abstract This paper examines the question raised by Louis Althusser concerning what it means for ideology to interpellate concrete individuals as concrete subjects. Under what conditions does ideological identification succeed or fail? I answer this question by analyzing three scenarios of interpellation: Erich Auerbach investigates the scene of successful police identification and arrest in connection with a revolt in the late Roman Empire; Karl Marx describes the adoption of Roman names, phrases, and costumes by French revolutionaries as the necessary conditions for bringing about bourgeois society; and finally, analyses of today’s political networks reveal an extensive crisis of interpellation manifested in controversies surrounding the naming and classification of political actors without official status.
{"title":"Benennungskrisen","authors":"Friedrich Balke","doi":"10.1515/iasl-2022-0009","DOIUrl":"https://doi.org/10.1515/iasl-2022-0009","url":null,"abstract":"Abstract This paper examines the question raised by Louis Althusser concerning what it means for ideology to interpellate concrete individuals as concrete subjects. Under what conditions does ideological identification succeed or fail? I answer this question by analyzing three scenarios of interpellation: Erich Auerbach investigates the scene of successful police identification and arrest in connection with a revolt in the late Roman Empire; Karl Marx describes the adoption of Roman names, phrases, and costumes by French revolutionaries as the necessary conditions for bringing about bourgeois society; and finally, analyses of today’s political networks reveal an extensive crisis of interpellation manifested in controversies surrounding the naming and classification of political actors without official status.","PeriodicalId":42506,"journal":{"name":"INTERNATIONALES ARCHIV FUR SOZIALGESCHICHTE DER DEUTSCHEN LITERATUR","volume":"47 1","pages":"156 - 173"},"PeriodicalIF":0.2,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46397870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"文学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abstract The essay draws out a conversation between Louis Althusser’s theory of ideology and his often-misunderstood notion of »symptomatic reading.« This conversation is staged by examining three pillars of Althusser’s theoretical intervention: the problem of humanism, Spinoza’s materialism of the imaginary, and Spinoza’s Biblical criticism. In doing so, the essay identifies a temporal logic of retention in the Spinozism of Althusser and the Althusser school, the productivity of which for a renewed, praxeologically informed materialist theory of reading is finally discussed.
{"title":"Vorbehalt","authors":"Patrick Hohlweck","doi":"10.1515/iasl-2022-0011","DOIUrl":"https://doi.org/10.1515/iasl-2022-0011","url":null,"abstract":"Abstract The essay draws out a conversation between Louis Althusser’s theory of ideology and his often-misunderstood notion of »symptomatic reading.« This conversation is staged by examining three pillars of Althusser’s theoretical intervention: the problem of humanism, Spinoza’s materialism of the imaginary, and Spinoza’s Biblical criticism. In doing so, the essay identifies a temporal logic of retention in the Spinozism of Althusser and the Althusser school, the productivity of which for a renewed, praxeologically informed materialist theory of reading is finally discussed.","PeriodicalId":42506,"journal":{"name":"INTERNATIONALES ARCHIV FUR SOZIALGESCHICHTE DER DEUTSCHEN LITERATUR","volume":"47 1","pages":"191 - 220"},"PeriodicalIF":0.2,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42182653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"文学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abstract Ever since Botho Strauß’ essay Anschwellender Bocksgesang (1993), contemporary literary texts and authors in Germany have been repeatedly valued as “right-wing”. Due to an ongoing shift of the political landscape, leading to changes in the meaning of right or left, this article suggests analyzing the social and discursive conditions which constitute the political evaluation of literature.
{"title":"‚Rechte Gegenwartsliteratur‘?","authors":"Nicolai Busch","doi":"10.1515/iasl-2022-0003","DOIUrl":"https://doi.org/10.1515/iasl-2022-0003","url":null,"abstract":"Abstract Ever since Botho Strauß’ essay Anschwellender Bocksgesang (1993), contemporary literary texts and authors in Germany have been repeatedly valued as “right-wing”. Due to an ongoing shift of the political landscape, leading to changes in the meaning of right or left, this article suggests analyzing the social and discursive conditions which constitute the political evaluation of literature.","PeriodicalId":42506,"journal":{"name":"INTERNATIONALES ARCHIV FUR SOZIALGESCHICHTE DER DEUTSCHEN LITERATUR","volume":"47 1","pages":"36 - 54"},"PeriodicalIF":0.2,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46717229","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"文学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Editorial","authors":"Mareike Schildmann, Till Breyer","doi":"10.1515/iasl-2022-0004","DOIUrl":"https://doi.org/10.1515/iasl-2022-0004","url":null,"abstract":"","PeriodicalId":42506,"journal":{"name":"INTERNATIONALES ARCHIV FUR SOZIALGESCHICHTE DER DEUTSCHEN LITERATUR","volume":"47 1","pages":"55 - 60"},"PeriodicalIF":0.2,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46492721","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"文学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abstract The essay ties in with current attempts at systematic reconstruction and reappropriation of the method of ideology critique. It argues that such attempts should not be satisfied with the reconstruction of an alleged core or basic essence, but should additionally address both the reasons for the historical decline of ideology critique and the new phenomena that lead to tensions with classical approaches to it.
{"title":"Thesen und Fragen zur Historizität und Aktualität der Ideologiekritik","authors":"Falko Schmieder","doi":"10.1515/iasl-2022-0005","DOIUrl":"https://doi.org/10.1515/iasl-2022-0005","url":null,"abstract":"Abstract The essay ties in with current attempts at systematic reconstruction and reappropriation of the method of ideology critique. It argues that such attempts should not be satisfied with the reconstruction of an alleged core or basic essence, but should additionally address both the reasons for the historical decline of ideology critique and the new phenomena that lead to tensions with classical approaches to it.","PeriodicalId":42506,"journal":{"name":"INTERNATIONALES ARCHIV FUR SOZIALGESCHICHTE DER DEUTSCHEN LITERATUR","volume":"47 1","pages":"61 - 78"},"PeriodicalIF":0.2,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66939667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"文学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abstract The paper provides elements for the actualization of a materialist critique of ideology in our supposedly post-ideological times. Referring to the work of Theodor W. Adorno, Jacques Derrida, and Slavoj Žižek, it shows that their ›ghostly vocabulary‹ opens up new perspectives on the historical materiality of ideological formations as well as new insights for the project of their critique.
{"title":"»Ein Gespenst geht um...«","authors":"F. Raimondi","doi":"10.1515/iasl-2022-0013","DOIUrl":"https://doi.org/10.1515/iasl-2022-0013","url":null,"abstract":"Abstract The paper provides elements for the actualization of a materialist critique of ideology in our supposedly post-ideological times. Referring to the work of Theodor W. Adorno, Jacques Derrida, and Slavoj Žižek, it shows that their ›ghostly vocabulary‹ opens up new perspectives on the historical materiality of ideological formations as well as new insights for the project of their critique.","PeriodicalId":42506,"journal":{"name":"INTERNATIONALES ARCHIV FUR SOZIALGESCHICHTE DER DEUTSCHEN LITERATUR","volume":"47 1","pages":"247 - 267"},"PeriodicalIF":0.2,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42994587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"文学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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