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Comparison of antimicrobial effect of selenium nanoparticles and silver nanoparticles coated orthodontic mini-implants – An in vitro study 纳米硒纳米粒子与纳米银纳米粒子包覆正畸微型种植体抗菌效果的比较——体外研究
IF 0.4 Q4 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2022-02-18 DOI: 10.25259/apos_99_2021
S. Subramanian, Prema Anbarasu, N. Navin, Sushmita R. Iyer
Mini-implants have earned a significant role in orthodontic treatment, by augmenting anchorage requirements. Peri-implantitis contributes to miniscrew failures where progressive peri-implant bone loss occurs in conjunction with soft-tissue inflammation due to the growth of microorganisms such as Streptococcus and Lactobacillus. Nanoparticles have increased surface area and have increased interactions with biological targets like bacteria. This study aims to investigate the antimicrobial activity of silver nanoparticles (AgNP) and selenium nanoparticles (SeNPs) on orthodontic mini-implants.Mini-implant (Ti-6Al-4V) was coated with AgNP and SeNP with biopolymer (Ti-BPAgNP and Ti-BPSeNP) by dip-coating technique. The crystal structure and crystallite size of AgNPs and SeNPs were characterized by the X-ray diffraction (XRD) method. The size distribution and morphology of SeNP and AgNP were determined by a scanning electron microscope (SEM). The antibacterial activity of Ti-BP-AgNP and Ti-BPSeNP was detected from the zone of inhibition by disk diffusion assay.The SEM image of AgNP was roughly spherical, uniformly distributed and SeNPs were spherical, well distributed on the biopolymer surface. The area of the zone of inhibition of Ti-BP-SeNP-coated mini-implants shows a negligible difference in antibacterial activity compared to Ti-BPAgNP-coated mini-implants.Ti-BP-AgNP and Ti-BP-SeNP showed that a strong antibacterial activity was against Lactobacillus and Staphylococcus aureus. Antibacterial activity against Streptococcus mutans was slightly less than observed in other bacteria. SeNP shows only a marginal difference in antibacterial activity when compared to AgNP.
微型种植体通过增加固支需求,在正畸治疗中发挥了重要作用。种植体周围炎会导致种植体周围骨质流失,同时由于链球菌和乳酸杆菌等微生物的生长而导致软组织炎症。纳米颗粒增加了表面积,并增加了与细菌等生物目标的相互作用。本研究旨在探讨纳米银粒子(AgNP)和纳米硒粒子(SeNPs)在正畸微型种植体中的抗菌活性。采用浸包技术将Ti-BPAgNP和Ti-BPSeNP生物聚合物分别涂覆在Ti-6Al-4V微型植入体上。采用x射线衍射(XRD)方法对AgNPs和SeNPs的晶体结构和晶粒尺寸进行了表征。通过扫描电镜(SEM)对SeNP和AgNP的尺寸分布和形貌进行了分析。采用圆盘扩散法从抑制区检测Ti-BP-AgNP和Ti-BPSeNP的抑菌活性。AgNP的SEM图像大致呈球形,分布均匀,SeNPs呈球形,分布在生物聚合物表面。与ti - bpagnp包被的微型植入物相比,ti - bp - senp包被的微型植入物的抑菌区显示出可忽略不计的抑菌活性差异。Ti-BP-AgNP和Ti-BP-SeNP对乳酸菌和金黄色葡萄球菌具有较强的抗菌活性。对变形链球菌的抑菌活性略低于其他细菌。与AgNP相比,SeNP在抗菌活性上仅表现出微小的差异。
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引用次数: 2
Non-surgical correction of Class III adolescent patient with TADs and Damon system: A case report 青少年三级TADs及Damon系统非手术矫正1例
IF 0.4 Q4 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2022-02-12 DOI: 10.25259/apos_101_2021
Analhaq Anvarhushen Shaikh, G. A. Kumar, G. Ramesh, Ganesh Chinthan, Shanthiprasad Indra
Here is a case report of a 16 year old female patient with Class III malocclusion with Class III molar relation on both sides. The patient was diagnosed with normodivergent face pattern, proclined upper anterior, and crowded lower anterior, concave profile, potentially competent lips, reverse overjet and 0% overbite, and shallow mentolabial sulcus. The treatment was planned with a maxillary splint, mini-screws in mandible, and Class III elastics for Phase 1 and Phase 2 fixed appliance using the passive self-ligation system. The facial changes produced as a result of treatment were directly related to skeletal and dentoalveolar modifications that were designed as goals for patient treatment.
本文报告一位16岁的女性患者,患有III类错牙合,双侧磨牙关系为III类。患者诊断为正常的面部形态,上前倾,下前挤,轮廓凹,嘴唇可能胜任,反向覆盖和0%覆盖咬合,心唇沟浅。治疗计划使用上颌夹板,下颌骨微型螺钉和III类弹性材料,用于第一期和第二期固定矫治器,使用被动自结扎系统。由于治疗而产生的面部变化与骨骼和牙槽骨的改变直接相关,这是患者治疗的目标。
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引用次数: 0
Articular eminence pneumatization in patients with different sagittal skeletal patterns: Cone-beam computed tomography study 不同矢状骨型患者的关节隆起充气:锥束计算机断层扫描研究
IF 0.4 Q4 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2022-02-11 DOI: 10.25259/apos_140_2021
S. Yesiltepe, H. T. Alkis, Elif Kurtuldu, Gulcin Kılcı
This study objectives to evaluate the type and degree of articular eminence pneumatization in individuals with different sagittal skeletal patterns.Cone-beam computed tomography images of 139 patients were included in the study. The population was divided into groups according to their sagittal skeletal anomalies by A point-nasion-B point angle measurement. The laterality, grade, and type of pneumatization were recorded. Pearson Chi-square test and Fisher’s exact test were performed to evaluate gender, sagittal skeletal anomalies, pneumatization type, and grade.A pneumatized articular eminence (PAT) was found in 74.8% of the population. Grade 1 pneumatization and the multilocular type where the most common pneumatization. There were no correlations between sagittal skeletal anomalies and pneumatization grades.The prevalence of PAT was high concerning the previous studies. However, there were no correlations between the sagittal skeletal anomalies, pneumatization type, and grade. Clinicians must always be aware of the potential for pneumatizations as they may cause untoward complications.
本研究的目的是评估不同矢状面骨骼类型的个体关节隆起充气的类型和程度。139例患者的锥束计算机断层扫描图像被纳入研究。采用A点- b点角度测量法,根据矢状骨异常情况将人群分为不同的组。记录侧位、分级和通气类型。Pearson卡方检验和Fisher精确检验评估性别、矢状面骨骼异常、气化类型和分级。在74.8%的人群中发现了气动关节隆起(PAT)。1级和多房型在其中最常见。矢状面骨骼异常与气化分级之间无相关性。在以往的研究中,PAT的患病率较高。然而,矢状面骨骼异常、气化类型和分级之间没有相关性。临床医生必须始终意识到潜在的肺炎,因为它们可能导致不良并发症。
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引用次数: 0
Trending topics in orthodontic treatment practices in the past 5 years: A longitudinal study on case reports 近5年来正畸治疗实践中的热点话题:病例报告的纵向研究
IF 0.4 Q4 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2022-02-04 DOI: 10.25259/apos_147_2021
T. Ozturk, Gokhan Coban
This study aimed to analyze the case reports published in the past 5 years in orthodontic journals in the Web of Science (WOS) indexes and evaluate the trending topics.Following a search conducted by entering the keyword “orthodontics” in the WOS Master Journal List search site, four journals in the Science Citation Index (SCI) and five journals in the Emerging Science Citation Index (ESCI) were included in the study, and case report articles published in these journals between 2016 and 2020 were examined. The case reports were analyzed by examining each issue of each journal published during these years. In addition, frequently studied topics were examined under seven headings.Only nine of the 16 journals in the list of related journals have published case reports in the past 5 years. The largest number of articles appeared in the American Journal of Orthodontics and Dentofacial Orthopedics for the SCI group and International Orthodontics for the ESCI group. When the frequently examined topics were evaluated, it was determined that the highest number of articles was fixed orthodontic treatments (53.4%), orthognathic surgery (18.9%), multidisciplinary treatments (6.5%), and treatments for individuals with general health problems (6.5%).The number of case reports published has gradually increased in the past 5 years. The number of articles in the journals included in the SCI is higher. The subject variety of case reports is too great to be limited to a narrow field.
本研究旨在分析Web of Science (WOS)正畸期刊近5年来发表的病例报告,并对其趋势话题进行评价。通过在WOS Master Journal List搜索网站中输入关键词“orthodontics”进行搜索,将4种SCI期刊和5种ESCI期刊纳入研究,并对2016年至2020年间在这些期刊上发表的病例报告文章进行分析。病例报告是通过检查这些年来出版的每份期刊的每期来分析的。此外,还在七个标题下审查了经常研究的题目。在相关期刊列表中的16种期刊中,只有9种在过去5年中发表了病例报告。SCI组在American Journal of Orthodontics and Dentofacial Orthopedics上发表的文章最多,ESCI组在International Orthodontics上发表的文章最多。当对经常检查的主题进行评估时,确定了最多的文章是固定正畸治疗(53.4%),正颌手术(18.9%),多学科治疗(6.5%)和一般健康问题个人治疗(6.5%)。在过去5年中,已发表的病例报告数量逐渐增加。被SCI收录期刊的文章数量较高。病例报告的主题种类太多,不能局限于一个狭窄的领域。
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引用次数: 0
Evaluation of quality and reliability of videos about orthodontics on TikTok (DouYin) 抖音TikTok(抖音)正畸视频质量与可靠性评价
IF 0.4 Q4 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2022-02-04 DOI: 10.25259/apos_141_2021
Pamir Meriç, D. Kılınç
TikTok is the world’s most popular short video application, where orthodontics-related content is viewed billions of times. This study aimed to evaluate the quality and reliability of video content about orthodontics on TikTok.TikTok mobile application was searched for videos with the hashtag “#orthodontics” on July 9, 2021. The content and quality of the first 150 videos were evaluated using the global quality score (GQS) and reliability score (modified DISCERN tool) which is an evaluation tool for health information on social media.The mean of the two researchers’ GQS values and reliability score was 2.1 ± 1.1 and 1.2 ± 1.4, respectively. There was no statistically significant difference between the median values of GQS and reliability score according to categorical descriptive variables (P > 0.050). A statistically significant weak positive correlation was found between like no. and reliability scores (r = 0.245; P = 0.037). Most of the videos were uploaded by orthodontists (72.6%).Both the quality and reliability of the content about orthodontics on TikTok were very low. Even the most of the accounts were professionals, they did not prefer to give scientific information due to the medium’s own dynamics and target population’s likes.
TikTok是世界上最受欢迎的短视频应用程序,其中与正畸相关的内容被观看了数十亿次。本研究旨在评估TikTok上有关正畸的视频内容的质量和可靠性。2021年7月9日,TikTok手机应用上搜索了“#orthodontics”标签的视频。使用全球质量评分(GQS)和可靠性评分(改进的DISCERN工具)对前150个视频的内容和质量进行评估,后者是社交媒体上健康信息的评估工具。两位研究者的GQS值和信度评分的平均值分别为2.1±1.1和1.2±1.4。GQS与信度评分中位数在分类描述变量上的差异无统计学意义(P > 0.050)。两者之间存在统计学上显著的弱正相关。信度得分(r = 0.245;P = 0.037)。上传视频最多的是正畸医师(72.6%)。TikTok上关于正畸的内容质量和可靠性都很低。即使大多数账户是专业人士,由于媒体自身的动态和目标人群的喜好,他们也不喜欢提供科学信息。
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引用次数: 4
A severe skeletal Class III malocclusion treated with Le Fort I combined with sagittal split ramus osteotomy, mandibular body ostectomy and tongue reduction surgery. A case report Le Fort I联合矢状裂支截骨、下颌骨体骨切除术及舌瓣复位手术治疗重度骨类错颌。病例报告
IF 0.4 Q4 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2022-02-04 DOI: 10.25259/apos_139_2021
H. Hotokezaka, Carmen Karadeniz, Y. Hotokezaka, T. Matsuo, N. Yoshida
This case report describes the orthodontic-orthognathic management of a 17-year-old male patient with extremely severe skeletal Class III malocclusion due to a marked mandibular protrusion with a small and narrowed upper jaw which increased the remarkable concave facial profile. Dental articulation was entirely lacking, resulting in great difficulty in masticating food. A two-jaw surgery combined with mandibular body ostectomy was performed to correct mandibular asymmetry and the severe sagittal skeletal discrepancy (Wits appraisal –36.5 mm and ANB angle –14.3°). Bi-maxillary surgery was performed in two-stages; the first surgery consisted of maxillary advancement with Le Fort I osteotomy followed by a second surgery where a combination of sagittal split ramus osteotomy (SSRO) and mandibular body ostectomy was performed to correct the severe mandibular prognathism. A partial glossectomy was also carried out to address macroglossia. After a total treatment time of 32 months, a Class I occlusion with a favorable facial profile and lip competence were obtained. The occlusion was made approximately ideal, and mastication improved remarkably. Three years after retention, the occlusion was stable and no relapse was observed. The patient’s complaints and orthodontic problems were completely resolved. Therefore, a combination of two-jaw surgeries with Le Fort I maxillary osteotomy, mandibular SSRO, mandibular ostectomy, and glossectomy may be a viable option in the correction of extremely severe anteroposterior skeletal discrepancy.
本病例报告描述了一名17岁男性患者的正畸-正颌治疗,该患者患有非常严重的骨骼III类错颌,原因是明显的下颌突出,上颌小而狭窄,增加了显着的凹面部轮廓。牙齿发音完全丧失,咀嚼食物有很大困难。采用双颌手术联合下颌骨体骨切除术纠正下颌不对称和严重矢状骨差异(Wits评估-36.5 mm, ANB角-14.3°)。双颌手术分两期进行;第一次手术包括上颌前移与Le Fort I截骨术,然后是第二次手术,其中矢状分裂支截骨术(SSRO)和下颌体截骨术联合进行矫正严重的下颌前突。部分舌切除术也进行了解决大舌。经过32个月的治疗,获得了一个具有良好面部轮廓和嘴唇能力的I类咬合。咬合近似理想,咀嚼功能明显改善。保留3年后,牙合稳定,无复发。患者的主诉和正畸问题得到彻底解决。因此,双颌手术联合Le Fort I上颌截骨术、下颌骨SSRO、下颌骨截骨术和舌骨切除术可能是矫正极其严重的前后骨差异的可行选择。
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引用次数: 1
Evaluation of white spot lesions around orthodontic brackets using different bonding agents – An in vivo study 不同粘结剂对正畸托槽周围白斑病变的评价-一项体内研究
IF 0.4 Q4 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2022-01-12 DOI: 10.25259/apos_8_2021
Vaibhav Vashishta, Rakesh K Kaul, Ankita Singh, S. Kapoor, S. Grover, Monisha Singhal
The objectives of the study were to assess the white spot lesions around orthodontic bracket macroscopically using two different bonding agents – one with amorphous calcium phosphate (ACP) (Aegis Ortho) and one without ACP (Transbond XT).The study comprises 10 patients from 14 to 23 years of age. Patients were divided into control and study groups. Forty premolar teeth were then observed (20 teeth in each group). Bonding procedure was done and brackets were positioned on all four 1st pre-molars teeth and pre-treatment photographs were taken. The experimental material used was Aegis Ortho composite (study group) and Transbond XT (control group). Debonding procedure (by Wing deformation technique) was performed after 16 weeks which led to adhesive fracture at composite resin adhesive bracket interface leaving essentially all adhesive on the enamel. Then, follow-up photographs were taken to evaluate each.Aegis Ortho containing ACP used for bonding purpose, provided lesser enamel demineralization than Transbond XT.Aegis Ortho for orthodontic bonding is significantly more beneficial and reliable, however, further investigations are also required to understand its clinical performance better.
本研究的目的是在宏观上评估正畸支架周围的白斑病变,使用两种不同的粘结剂-一种是无定形磷酸钙(ACP) (Aegis Ortho),一种是无ACP (Transbond XT)。该研究包括10名年龄在14至23岁之间的患者。患者被分为对照组和研究组。观察前磨牙40颗(每组20颗)。完成粘接程序,在所有四颗第一前磨牙上放置托槽,并拍摄治疗前照片。实验材料采用Aegis Ortho复合材料(研究组)和Transbond XT(对照组)。16周后进行脱粘手术(通过翼变形技术),导致复合树脂胶粘剂支架界面粘接剂断裂,基本上所有粘接剂都在牙釉质上。然后,拍摄后续照片来评估每一个。含ACP的Aegis Ortho牙釉质脱矿效果较Transbond XT牙釉质脱矿效果好。Aegis Ortho用于正畸粘接明显更有益和可靠,但也需要进一步的研究来更好地了解其临床表现。
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引用次数: 0
Craniofacial measurements in children with sella turcica shape’s anomalies 蝶鞍形状异常儿童颅面测量
IF 0.4 Q4 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2022-01-12 DOI: 10.25259/apos_11_2021
W. Hammami, H. Gmati, Khouloud Ezzina, Y. Elelmi, C. Baccouche, Soumaya Touzi, H. Ghedira
The objective of the study is to evaluate the cephalometric measurements of Tunisian children who presented sella turcica’s (ST) shape anomalies.This cross-sectional study was conducted between January and June 2019 in the Department of Pediatric Dentistry of Monastir and Faculty of Dentistry of Tunisia. Radiographs were gathered from patients aged between 7 and 12 years old (n = 104) who had consulted for a malocclusion. The inclusion criteria were considered as follows: Good visibility of anatomic structures and absence of congenital craniofacial deformities. We excluded bad radiographs with errors and discrepancies: Double limits, deformities as well as children having hereditary craniofacial anomalies and underlying diseases. The cephalometric analysis was conducted according to Segner and Hassund’s method. ST’s shape was identified according to Axelsson’s classification modified by Becktor. The sample size was divided into groups: Group 1 with normal ST’s shape and Group 2 with sella’s anomaly. Statistics were performed using IBM SPSS STATISTICS 22. Data normality has been tested using Shapiro–Wilk test. The normality of variance was investigated too with Levene’s test, and comparison of means between groups was performed with t-test.The prevalence of aberrations of ST’s form in Tunisian children is about 59.6%. The inclination of upper incisors to the maxilla differed in children with ST’s anomaly compared to normal kids. Children with sella aberration are characterized by retroclination of upper incisors to the maxilla. The variables which showed a statistically significant relationship between abnormalities of ST and cephalometric measurements were 1+NA with P = 0.03 and NL-NSL with P = 0.04.The prevalence of ST’s shape anomalies in Tunisian children is about two-thirds. It seems that the anomaly of ST influences the position of the maxilla to the cranial base and the position of upper incisors to the maxilla.
该研究的目的是评估突尼斯儿童谁提出蝶鞍(ST)形状异常的头测量。这项横断面研究于2019年1月至6月在莫纳斯提尔儿科牙科科和突尼斯牙科学院进行。收集了年龄在7 - 12岁之间(n = 104)因错牙合就诊的患者的x线片。纳入标准考虑如下:解剖结构可视性好,无先天性颅面畸形。我们排除了有错误和差异的不良x线片:双重限制、畸形以及有遗传性颅面异常和潜在疾病的儿童。根据Segner和Hassund的方法进行头颅测量分析。ST的形状是根据经Becktor修改的Axelsson的分类来确定的。将样本量分为两组:1组ST形状正常,2组sella异常。采用IBM SPSS Statistics 22进行统计学分析。使用Shapiro-Wilk检验对数据的正态性进行了检验。方差正态性采用Levene检验,组间均值比较采用t检验。突尼斯儿童中ST型异常的患病率约为59.6%。ST异常患儿上切牙对上颌骨的倾斜度与正常患儿不同。鞍位畸变儿童的特点是上切牙向上颌骨后倾。ST与头颅测量异常有统计学意义的变量为1+NA (P = 0.03)和NL-NSL (P = 0.04)。突尼斯儿童中ST形状异常的患病率约为三分之二。ST的异常可能影响上颌骨与颅底的位置以及上切牙与上颌骨的位置。
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引用次数: 0
Modified transpalatal arch to correct sagging of palatal cusp of maxillary 2nd molar 改良经腭弓矫治上颌第二磨牙腭尖下垂
IF 0.4 Q4 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2022-01-12 DOI: 10.25259/apos_83_2021
Namit Nagar
“Sagging” of the palatal cusp of upper second molars is a common finding observed during orthodontic treatment which may develop heavy balancing side contacts, which have been found to be detrimental to harmonious function of the masticatory system. Various modifications of transpalatal arch (TPA) are advocated to correct crossbite, but most of them will utilize an additional step of soldering a wire attachment to TPA. In this clinical pearl, the TPA was fabricated using a single wire component, eliminating an additional step of soldering.
上颌第二磨牙腭尖“下垂”是正畸治疗过程中常见的现象,可能会产生沉重的平衡侧接触,这不利于咀嚼系统的和谐功能。各种改良的经腭弓(TPA)被提倡矫正十字咬合,但大多数将利用额外的步骤,焊接金属丝附着在TPA。在这个临床珍珠中,TPA是使用单线组件制造的,省去了焊接的额外步骤。
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引用次数: 0
Age-related osteogenesis on lateral force application to rat incisor – Part III: Periodontal and periosteal bone remodeling 对大鼠门牙施加侧力的年龄相关成骨作用-第三部分:牙周和骨膜骨重塑
IF 0.4 Q4 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2022-01-12 DOI: 10.25259/apos_125_2021
Sung-Seo Mo, Jin-Wook Kim, H. Baik, H. Giap, Kee-Joon Lee
This study was aimed to compare the histological pattern of bone modeling on either periodontal or periosteal side induced by lateral orthodontic tooth movement in different age groups.A total of 50 male Sprague-Dawley rats (25 rats in the adult group – 52 weeks and 25 rats in the young group – 10 weeks) were utilized in this study. Each age group was classified into the control, 3 days, 7 days, 14 days, and 21 days groups (five rats in each) by the duration of experimental device application. A double-helical spring was produced using 0.014” stainless steel wire to provide 40 g lateral force to the left and right incisors. Hematoxylin-eosin staining, proliferating cell nuclear antigen (PCNA) immunohistochemical staining, fibroblast growth factor receptor 2 (FGFR2) immunohistochemical staining, and Masson trichrome staining were performed; and the slides were subject to histological examination.In 7 days, active bone modeling represented by the scalloped surface was observed on the periosteal side of the crestal and middle alveolus at the pressure side in the young group, while similar changes were observed only on the crestal area in the adult group. In the young group, the number of PCNA-positive cells increased significantly on the crestal area and middle alveolus on the 3, 7, and 14 day groups, with subsequent decrease at 21 days. In the adult group, PCNA-positive cells were localized on the crestal area throughout the period. In the young group, FGFR2-positive cells were observed mainly on the crestal and middle alveolus at 3, 7, and 14 days than the control group. In the adult group, these cells appeared on the crestal and middle alveolus in the 3 days group, but mainly on the crestal area at 14 days. In the young group, FGFR2-positive cells were observed on the crestal and middle alveolus on the 3, 7, and 14 days groups more than on the control group. In the adult group, these cells appeared on the crestal and middle alveolus in the 3 days group, but mainly on the crestal area in the 14 days group. In Masson trichrome stain, an increased number of type I collagen fibers were observed after helical spring activation in both age groups. Large resorption lacunae indicating undermining bone resorption were progressively present in both young and adult groups.According to these results, orthodontic tooth movement may stimulate cell proliferation and differentiation primarily on the periosteal side according to progressive undermining bone resorption on the periodontal side. This response may lead to prominent bone modeling during tooth movement in the young group, compared to the relatively delayed response in the adult group.
本研究旨在比较不同年龄组正畸牙侧移引起的牙周侧和骨膜侧骨模型的组织学模式。实验选用雄性Sprague-Dawley大鼠50只(成年组25只,52周龄,幼龄组25只,10周龄)。各组按实验装置使用时间分为对照组、3天组、7天组、14天组和21天组,每组5只。使用0.014 "不锈钢丝制作双螺旋弹簧,向左右门牙提供40克的侧向力。苏木精-伊红染色、增殖细胞核抗原(PCNA)免疫组化染色、成纤维细胞生长因子受体2 (FGFR2)免疫组化染色、马松三色染色;并对载玻片进行组织学检查。在7天内,幼鼠组在牙嵴侧骨膜侧和压力侧中牙槽区观察到以扇形面为代表的活跃骨模型,而成鼠组仅在牙嵴区观察到类似的变化。在幼龄组,3、7、14天时,冠区和中肺泡的pcna阳性细胞数量显著增加,21天时呈下降趋势。在成人组中,pcna阳性细胞在整个期间都定位于嵴区。在幼龄组中,与对照组相比,在第3、7和14天,fgfr2阳性细胞主要出现在嵴和中间肺泡上。在成鼠组,这些细胞在第3天出现在嵴和中肺泡上,但在第14天主要出现在嵴区。在幼龄组中,与对照组相比,在第3、7和14天组的嵴和中间肺泡上观察到更多的fgfr2阳性细胞。在成鼠组中,这些细胞在第3天出现在牙槽嵴和中间,而在第14天主要出现在牙槽嵴区域。在马松三色染色中,螺旋弹簧激活后,两个年龄组的I型胶原纤维数量均有所增加。大的骨吸收腔隙表明破坏骨吸收在年轻人和成年人中逐渐出现。根据这些结果,正畸牙齿的运动可以刺激细胞增殖和分化,主要是在骨膜侧,根据进行性破坏骨吸收在牙周侧。这种反应可能导致年轻组在牙齿移动过程中出现明显的骨模型,而成年组的反应相对延迟。
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引用次数: 0
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APOS Trends in Orthodontics
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