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2021 IEEE International Symposium on Medical Measurements and Applications (MeMeA)最新文献

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BLE-based approach for detecting daily routine changes 基于ble的检测日常变化的方法
Pub Date : 2021-06-23 DOI: 10.1109/MeMeA52024.2021.9478752
Ana Jiménez Martín, Ismael Miranda Gordo, David Gualda Gómez, S. G. D. Villa, Sergio Lluva Plaza, Juan Jesús García Domínguez
This work proposes a system to detect changes in daily routines in a controlled environment, such as a sensorized-home. Variations in routines can be indicative of physical or cognitive decline in elderly adults, which makes it very attractive to support independent living and healthy ageing. Our proposal is based on an indoor symbolic location system based on low-cost and easy-to-install Bluetooth Low Energy (BLE) transmitter beacons, together with a mobile receiver. The user's symbolic location is estimated from the Received Signal Strength Indicator (RSSI) and K-Nearest Neighbour (KNN) model, which is merged with the acceleration provided by the receiving mobile device. The location is used to estimate the time spent in each monitored room, to infer a time-based routine. The symbolic localization has an accuracy higher than 96%. The subsequent daily monitoring allows for the detection of variations with respect to a defined routine that can serve as an alarm for the user, family members or caregivers.
这项工作提出了一种在受控环境中检测日常生活变化的系统,例如感应式家庭。日常生活的变化可能表明老年人的身体或认知能力下降,这使得支持独立生活和健康老龄化非常有吸引力。我们的提案是基于一个室内符号定位系统,该系统基于低成本和易于安装的蓝牙低功耗(BLE)发射机信标以及移动接收器。用户的符号位置是根据接收信号强度指标(RSSI)和k近邻(KNN)模型估计的,该模型与接收移动设备提供的加速度合并。该位置用于估计在每个监控房间中花费的时间,以推断基于时间的例行程序。符号定位的准确率在96%以上。随后的日常监测允许检测与已定义的例行程序相关的变化,这些变化可以作为用户,家庭成员或护理人员的警报。
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引用次数: 3
Kinect-based wearable prototype system for ataxic patients neurorehabilitation: software update for exergaming and rehabilitation 基于kinect的共济失调患者神经康复可穿戴原型系统:运动与康复软件更新
Pub Date : 2021-06-23 DOI: 10.1109/MeMeA52024.2021.9478668
Michela Franzo', Simona Pascucci, M. Serrao, F. Marinozzi, F. Bini
The aim of this study is to evaluate the differences introduced by an update of implemented code between the two version of prototype for ataxic patients’ neurorehabilitation device. The rehabilitation consists in virtual exercise for the patient to improve his control of the upper arm during daily movement. The prototype is based on the Microsoft Kinect device to acquire subject’s position and on the Arduino board with accelerometer/gyroscope sensor to acquire kinematics quantities of the wrist during the task. Two subjects were analysed with 2.0 version of the prototype and they were compared to 2 of 20 subjects selected from the first control group to highlight the differences between the two versions.
本研究的目的是评估两个版本的原型之间的差异引入了实施代码的更新为共济失调患者的神经康复装置。康复包括虚拟运动,以提高患者在日常活动中对上臂的控制。该原型基于微软Kinect设备来获取受试者的位置,并在Arduino板上带有加速度计/陀螺仪传感器来获取任务期间手腕的运动学量。用2.0版本的原型对两名受试者进行分析,并将他们与从第一个对照组中选出的20名受试者中的2名进行比较,以突出两个版本之间的差异。
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引用次数: 3
Non-Linear and Chaos-based Analysis of Electroretinogram 视网膜电图非线性混沌分析
Pub Date : 2021-06-23 DOI: 10.1109/MeMeA52024.2021.9478719
S. Behbahani, S. Rajan
Electroretinogram (ERG) is well-known for direct retinal function measurement. ERG responses to flicker stimulation can cause cyclic and oscillating changes in amplitude. Flicker response analyses are mostly based on amplitude and implicit time. However, non-linear analysis can also provide valuable information about the retinal function. In this paper, we investigate the flicker response using non-linear and chaotic features such as Approximate Entropy (ApEn), Hurst Exponent (HE), and Largest Lyapunov Exponent (LLE). Flicker responses were obtained from four groups with 16 subjects in each: one group with healthy subjects and three groups with central retinal vascular occlusion (CRVO), diabetic retinopathy (DR), and retinitis pigmentosa (RP) subjects, respectively. Statistical analysis shows that these non-linear and chaosbased features can distinguish the diseases and further indicate that the ERG has more complexity in healthy subjects than retinal disease subjects.
视网膜电图(ERG)是众所周知的直接测量视网膜功能。闪烁刺激下的ERG反应可引起振幅的循环和振荡变化。闪烁响应分析主要基于幅值和隐式时间。然而,非线性分析也可以提供有关视网膜功能的有价值的信息。本文利用近似熵(ApEn)、赫斯特指数(HE)和最大李雅普诺夫指数(LLE)等非线性和混沌特征来研究闪烁响应。在四组(每组16人)中获得闪烁反应:一组为健康受试者,三组分别为视网膜中央血管闭塞(CRVO)、糖尿病视网膜病变(DR)和视网膜色素变性(RP)受试者。统计分析表明,这些非线性和混沌特征可以区分疾病,进一步表明健康受试者的ERG比视网膜疾病受试者具有更大的复杂性。
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引用次数: 0
Detection of Sleep Apnea from Single-Lead ECG: Comparison of Deep Learning Algorithms 单导联心电图检测睡眠呼吸暂停:深度学习算法的比较
Pub Date : 2021-06-23 DOI: 10.1109/MeMeA52024.2021.9478745
Mahsa Bahrami, M. Forouzanfar
Apnea is a prevalent sleep disorder which has detrimental impacts on human health and quality of life. Accurate automatic algorithms for the detection of sleep apnea are needed for analyzing long-term sleep data and monitoring and management of its side effects and consequences. Among different approaches for automatic detection of sleep apnea from biosignals, deep learning algorithms are of particular interest as, unlike conventional machine learning algorithms, they do not rely on expert crafted features. In this paper, we developed and evaluated a number of different deep learning models for the detection of sleep apnea from a single-lead electrocardiogram (ECG) signal. ECG R-peak amplitude and R-R intervals were extracted, and power spectral analysis was performed to align the R-peak amplitude and the R-R intervals in frequency domain. Convolutional neural network (CNN), long short-term memory (LSTM), bidirectional LSTM, gated recurrent unit, and deep hybrid models were implemented and analyzed. The performance of deep learning algorithms was evaluated on an apnea-ECG dataset of 70 recordings divided into a learning set of 35 records and a test of 35 records. The best accuracy, sensitivity, specificity, and F1-score on the test data were 80.67%, 75.04%, 84.13%, and 74.72%, respectively, with a hybrid CNN and LSTM network. The results show promise toward improved apnea detection using deep learning.
呼吸暂停是一种普遍存在的睡眠障碍,对人类健康和生活质量有不利影响。需要精确的自动算法来检测睡眠呼吸暂停,以分析长期睡眠数据并监测和管理其副作用和后果。在从生物信号中自动检测睡眠呼吸暂停的不同方法中,深度学习算法特别令人感兴趣,因为与传统的机器学习算法不同,它们不依赖于专家精心制作的特征。在本文中,我们开发并评估了许多不同的深度学习模型,用于从单导联心电图(ECG)信号中检测睡眠呼吸暂停。提取心电r -峰值幅度和R-R区间,进行功率谱分析,将r -峰值幅度和R-R区间在频域对齐。对卷积神经网络(CNN)、长短期记忆(LSTM)、双向LSTM、门控循环单元和深度混合模型进行了实现和分析。深度学习算法的性能在一个由70条记录组成的呼吸暂停-心电图数据集上进行评估,该数据集分为35条记录的学习集和35条记录的测试集。CNN和LSTM混合网络在测试数据上的准确率、灵敏度、特异性和f1评分分别为80.67%、75.04%、84.13%和74.72%。研究结果显示,利用深度学习改进呼吸暂停检测大有希望。
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引用次数: 18
Classification-Based Screening of Phlebopathic Patients using Smart Socks 使用智能袜子对静脉病患者进行分类筛查
Pub Date : 2021-06-23 DOI: 10.1109/MeMeA52024.2021.9478688
Emanuele D'Angelantonio, Leandro Lucangeli, V. Camomilla, F. Mari, Guido Mascia, A. Pallotti
Telemedicine consists in the delivery of health care services, where patients and providers are separated by distance. Telemonitoring facilities play an important role in remote assistance programs, particularly in assisting patients suffering from chronic afflictions, such as phlebopathic diseases (e.g. chronic venous disease and diabetic foot). When these pathologies worsen, complications can be serious. In fact, foot deformities lead to variations of plantar load, formation of ulcers and, in the worst case, to amputation. Consequently, these pathologies cause huge expenses for the health care system. We propose a framework for screening and early detection of phlebopathic diseases insurgence, based on dynamic tests for functional assessment where patients wear sensorized socks. Socks used in this study integrate force and inertial sensors to provide information on plantar pressures and person’s movement. We show results of a feasibility study including 42 patients, with a balance of 21 healthy patients and 21 with phlebopathic diseases. Data gathered from wearables were automatically elaborated through machine learning techniques in order to obtain a binary classifier identifying whether or not a patient shows pathological gait. Results show that our best classifier has high positive predictive value and high sensitivity, with F1-score equal to 92.1%.
远程医疗包括提供卫生保健服务,患者和提供者因距离而分开。远程监测设施在远程援助方案中发挥着重要作用,特别是在帮助患有慢性疾病,如静脉病(如慢性静脉疾病和糖尿病足)的患者方面。当这些病理恶化时,并发症可能会很严重。事实上,足部畸形会导致足底负荷的变化,溃疡的形成,在最坏的情况下,导致截肢。因此,这些疾病给医疗保健系统带来了巨大的开支。我们提出了一个框架,筛选和早期发现静脉病叛乱,基于动态测试的功能评估,患者穿感测袜子。在这项研究中使用的袜子集成了力和惯性传感器,以提供足底压力和人的运动信息。我们展示了一项可行性研究的结果,包括42名患者,其中21名健康患者和21名静脉病患者。从可穿戴设备收集的数据通过机器学习技术自动细化,以获得识别患者是否表现出病态步态的二元分类器。结果表明,我们的最佳分类器具有较高的阳性预测值和较高的灵敏度,f1得分为92.1%。
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引用次数: 5
Gait Parameters of Elderly Subjects in Single-task and Dual-task with three different MIMU set-ups 三种不同MIMU设置下老年受试者单任务和双任务的步态参数
Pub Date : 2021-06-23 DOI: 10.1109/MeMeA52024.2021.9478735
E. Digo, E. Panero, V. Agostini, L. Gastaldi
The increasing average age of the population emphasizes the strong correlation between cognitive decline and gait disorders of elderly people. Wearable technologies such as magnetic inertial measurement units (MIMUs) have been ascertained as a suitable solution for gait analysis. However, the relationship between human motion and cognitive impairments should still be investigated, considering outcomes of different MIMU set-ups. Accordingly, the aim of the present study was to compare single-task and dual-task walking of an elderly population by using three different MIMU set-ups and correlated algorithms (trunk, shanks, and ankles). Gait sessions of sixteen healthy elderly subjects were registered and spatio-temporal parameters were selected as outcomes of interest. The analysis focused both on the comparison of walking conditions and on the evaluation of differences among MIMU set-ups. Results pointed out the significant effect of cognition on walking speed (p = 0.03) and temporal parameters (p ≤ 0.05), but not on the symmetry of gait. In addition, the comparison among MIMU configurations highlighted a significant difference in the detection of gait stance and swing phases (for shanks-ankles comparison p < 0.001 in both single and dual tasks, for trunk-ankles comparison p < 0.001 in single task and p < 0.01 in dual task). Overall, cognitive impact and MIMU set-ups revealed to be fundamental aspects in the analysis of gait spatio-temporal parameters in a healthy elderly population.
人口平均年龄的增长强调了老年人认知能力下降与步态障碍之间的强烈相关性。磁性惯性测量单元(MIMUs)等可穿戴技术已被确定为步态分析的合适解决方案。然而,考虑到不同MIMU设置的结果,人类运动与认知障碍之间的关系仍有待研究。因此,本研究的目的是通过使用三种不同的MIMU设置和相关算法(躯干、小腿和脚踝)来比较老年人的单任务和双任务行走。对16名健康老年人的步态过程进行记录,选取时空参数作为感兴趣的结果。分析的重点是行走条件的比较和MIMU设置之间差异的评估。结果表明,认知对步行速度(p = 0.03)和时间参数(p≤0.05)有显著影响,但对步态对称性无显著影响。此外,MIMU配置之间的比较突出了步态姿态和摇摆相位检测的显著差异(单任务和双任务中小腿-脚踝比较p < 0.001,单任务中躯干-脚踝比较p < 0.001,双任务中p < 0.01)。总体而言,认知影响和MIMU设置揭示了健康老年人步态时空参数分析的基本方面。
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引用次数: 1
Automatic processing protocol to evaluate the impact of functional network damage and reorganization on cognitive functions after stroke 评估脑卒中后功能性网络损伤和重组对认知功能影响的自动处理协议
Pub Date : 2021-06-23 DOI: 10.1109/MeMeA52024.2021.9478769
L. Svobodová, R. Janca, P. Jiruška
An ischemic stroke is a local lesion that disrupts the large-scale structural and functional connectivity of the brain. Although local, the ischemic stroke often leads to deficits in cognitive functions which can’t be explained by local brain damage. It is believed that stroke-induced large-scale network alteration represents the mechanisms responsible for a decline in cognitive functions which are dependent on large-scale integration. To gain insight into the pathophysiological principles of how a local lesion results in a global cognitive decline requires a reliable and robust algorithm that can quantify the relationship between cognitive functions and network properties. In this study, we have developed, optimized, and tested a processing pipeline to parameterize complex neuropsychological evaluation and determine the functional connectivity from high-density EEG recordings. The developed algorithm was applied on a cohort of 27 patients who suffered a stroke and who were underwent cognitive examinations and high-density EEG monitoring one and two years after the stroke. The developed automatic algorithm demonstrated that it can reliably estimate functional connectivity and that it is robust against the physiological and technical artifacts. The proposed processing pipeline allows an unbiased and quantitative characterization of cognitive performance and its comparison with functional connectivity alterations.
缺血性中风是一种局部病变,它破坏了大脑的大规模结构和功能连接。缺血性中风虽然是局部的,但往往导致认知功能的缺陷,这不能用局部脑损伤来解释。人们认为,中风引起的大规模网络改变代表了依赖于大规模整合的认知功能下降的机制。为了深入了解局部病变如何导致整体认知能力下降的病理生理原理,需要一种可靠且稳健的算法,可以量化认知功能和网络特性之间的关系。在这项研究中,我们开发、优化并测试了一种处理管道,用于参数化复杂的神经心理学评估,并从高密度脑电图记录中确定功能连接。开发的算法应用于27名中风患者,他们在中风后1年和2年接受认知检查和高密度脑电图监测。所开发的自动算法表明,它可以可靠地估计功能连接,并且对生理和技术伪像具有鲁棒性。提出的处理管道允许对认知表现进行公正和定量的表征,并将其与功能连接改变进行比较。
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引用次数: 0
Smartwatches selection: market analysis and metrological characterization on the measurement of number of steps 智能手表的选择:对步数测量的市场分析和计量特性
Pub Date : 2021-06-23 DOI: 10.1109/MeMeA52024.2021.9478770
S. Casaccia, G. M. Revel, L. Scalise, Giacomo Cucchieri, L. Rossi
This paper is focused on identifying the accuracy of smartwatches (SWs) on the measurement of number of steps. Five SWs have been identified based on technical characteristics and costs from a list of 32 SWs available on the market. A metrological characterization on the selected SWs has been made on six subjects wearing all the SWs and doing walking activity with natural, slow and fast pace. R, R2 and statistical confidence, with coverage factor equal to 2, are computed considering videos as reference system to identify the number of steps. The overall statistical confidence is 4.2% for natural pace, 7.5% for the slow pace and 7.1% for the fast pace.
本文主要研究智能手表在步数测量上的准确性。根据技术特点和成本,我们从市面上可供选择的32种水处理设备中选出了5种。对6名受试者穿戴所有的SWs,进行自然、慢速和快速的步行活动,对所选的SWs进行计量学表征。以视频为参照系,计算R、R2和统计置信度,覆盖因子为2,识别步数。总体统计置信度自然步为4.2%,慢步为7.5%,快步为7.1%。
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引用次数: 1
Deep Convolutional Feature-Based Fluorescence-to-Color Image Registration 基于深度卷积特征的荧光-彩色图像配准
Pub Date : 2021-06-23 DOI: 10.1109/MeMeA52024.2021.9478607
Xingxing Liu, Tri Quang, Wenxiang Deng, Yang Liu
Fluorescence imaging has been widely utilized in various clinical applications. As a functional imaging modality, NIR fluorescence imaging often does not offer sufficient structural details. Therefore, structural imaging such as color reflectance overlaid with fluorescence imaging represents a superior approach for surgical visualization. Image registration of color reflectance and NIR fluorescence is needed for accurate overlay. In this study, we have implemented a deep convolutional algorithm for feature-based fluorescence-to-color image registration. Software-hardware codesign was conducted. Several sets of experiments were performed on biological tissues to compare the performance of our algorithm and traditional methods. We have demonstrated the feasibility of deep convolutional feature-based fluorescence-to-color image registration. To our best knowledge, this is the first demonstration of deep learning-based image registration between fluorescence and color imageries.
荧光成像已广泛应用于各种临床应用。作为一种功能成像方式,近红外荧光成像往往不能提供足够的结构细节。因此,结构成像,如彩色反射叠加荧光成像是外科可视化的一种优越方法。为了实现准确的叠加,需要对彩色反射率和近红外荧光图像进行配准。在这项研究中,我们实现了一种基于特征的荧光到彩色图像配准的深度卷积算法。进行软硬件协同设计。在生物组织上进行了几组实验,比较了该算法与传统方法的性能。我们已经证明了基于深度卷积特征的荧光到彩色图像配准的可行性。据我们所知,这是荧光图像和彩色图像之间基于深度学习的图像配准的第一次演示。
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引用次数: 0
PsySuite, an Android App for behavioural tests in the temporal domain PsySuite,一个用于时间域行为测试的安卓应用程序
Pub Date : 2021-06-23 DOI: 10.1109/MeMeA52024.2021.9478724
A. Inuggi, Alessia Tonelli, M. Gori
We present PsySuite, an Android App designed to perform multimodal behavioral tests in the temporal domain. This class of tests consists in delivering either unimodal or multimodal visual, acoustic and tactile stimuli and asking participants to evaluate their temporal features: duration, temporal distance between stimuli and simultaneity across different modalities. The accuracy and reproducibility of our stimuli production mechanism was evaluated with an oscilloscope on two different smartphones models. Then, we validated the App running two versions of the double-flash illusion (DFI) test in seven healthy adults. DFI was selected as it induces a perceptual illusion only when stimuli are precisely delivered within few milliseconds. We found the App could reliably produce stimuli with a minimum duration of 7 ms, 17 ms and 35 ms respectively for acoustic, visual and tactile stimuli. Oboe library outclassed AudioTrack solution in playing pairs of sounds, whilst visual and tactile performance was highly dependent on the smartphone’s model used. In the DFI test using "long" stimuli (35 ms) we did not find the flash illusion effect. We could run the "short" (audio: 7 ms, visual: 17 ms) stimuli version only with audio-visual stimuli and we found a strong effect consistent with the literature using classical experimental, PC-based, setups. These results suggest that our PsySuite App can be used to run highly demanding audio-visual psychophysics experiments obtaining the same effect found with classical setups.
我们提出PsySuite,一个安卓应用程序,旨在执行多模态行为测试在时间域。这类测试包括提供单模态或多模态视觉、听觉和触觉刺激,并要求参与者评估其时间特征:持续时间、刺激之间的时间距离和不同模态的同时性。我们的刺激产生机制的准确性和可重复性用示波器在两种不同的智能手机模型上进行了评估。然后,我们在7名健康成人中运行两个版本的双闪错觉(DFI)测试来验证应用程序。之所以选择DFI,是因为只有当刺激在几毫秒内精确传递时,它才会引起感知错觉。我们发现该应用程序可以可靠地产生最小持续时间分别为7 ms、17 ms和35 ms的听觉、视觉和触觉刺激。双簧管库在播放成对的声音时优于AudioTrack解决方案,而视觉和触觉性能高度依赖于所使用的智能手机型号。在使用“长”刺激(35 ms)的DFI测试中,我们没有发现闪光错觉效应。我们可以只使用视听刺激运行“短”(音频:7毫秒,视觉:17毫秒)刺激版本,我们发现使用经典实验,基于pc的设置的强烈效果与文献一致。这些结果表明,我们的PsySuite应用程序可以用于运行高要求的视听心理物理学实验,获得与经典设置相同的效果。
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引用次数: 0
期刊
2021 IEEE International Symposium on Medical Measurements and Applications (MeMeA)
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