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2021 IEEE International Symposium on Medical Measurements and Applications (MeMeA)最新文献

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Innovative Smart Face Mask to Protect Workers from COVID-19 Infection 创新智能口罩,保护工人免受COVID-19感染
Pub Date : 2021-06-23 DOI: 10.1109/MeMeA52024.2021.9478739
A. Fois, F. Tocco, A. Dell'Osa, Laura Melis, Ugo Bertelli, A. Concu, A. M. Bertetto, Carmen Serra
The most frequent prodromes of COVID-19 infection are fever and signs/symptoms of incipient respiratory diseases such as cough and shortness of breath or tachypnea. However, it is not infrequent that in patients infected with COVID-19, in addition to respiratory manifestations, cardiac rhythm alterations are also present which can be an early sign of an acute cardiovascular syndrome. It is therefore of utmost importance, especially for health care and civil protection workers who are most exposed to the infection, to detect the prodromal symptoms of this infection in order to be able to make a diagnosis of possible positivity to COVID-19 infection as quickly as possible and therefore to provide their immediate insertion in the isolation/therapy protocols. Here a prototype of a smart face mask is presented: the AG47-SmartMask. In addition to having the function of both an active and passive anti COVID-19 filter, the latter by an electro-heated filter brought to a minimum temperature of 38°C, the AG47-SmartMask also allows the continuous monitoring of numerous cardio-pulmonary variables. Several specific sensors are incorporated into the mask in an original way that assess the inside mask temperature, relative humidity and air pressure together with the auricular assessment of body temperature, heart rate and percentage of oxygen saturation of haemoglobin. Sensors work in synergy with an advanced telemedicine platform. To validate the device, twenty workers engaged in a vegetable packaging chain tested the tool simulating, while working, both tachypnea and cough, and the AG47-SmartMask faithfully quantified the simulated dyspnoic events.
COVID-19感染最常见的前驱症状是发烧和早期呼吸道疾病的体征/症状,如咳嗽、呼吸短促或呼吸急促。然而,在感染COVID-19的患者中,除了呼吸症状外,心律改变也很常见,这可能是急性心血管综合征的早期征兆。因此,至关重要的是,特别是对最容易感染的卫生保健和民防工作人员来说,检测这种感染的前驱症状,以便能够尽快诊断出COVID-19感染可能呈阳性,从而立即将其纳入隔离/治疗方案。这里介绍了一种智能口罩的原型:AG47-SmartMask。除了具有主动和被动抗COVID-19过滤器的功能(后者通过电热过滤器达到最低温度38°C)外,AG47-SmartMask还可以连续监测许多心肺变量。几个特定的传感器以一种原始的方式集成到口罩中,评估口罩内的温度、相对湿度和气压,以及耳部对体温、心率和血红蛋白氧饱和度的评估。传感器与先进的远程医疗平台协同工作。为了验证该设备,20名从事蔬菜包装链的工人在工作时测试了该工具模拟呼吸急促和咳嗽,AG47-SmartMask忠实地量化了模拟的呼吸困难事件。
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引用次数: 8
Toward Continuous Estimation of Cardiorespiratory Parameters in Oscillometry: A Simulation Study 振荡测量法中心肺参数的连续估计:模拟研究
Pub Date : 2021-06-23 DOI: 10.1109/MeMeA52024.2021.9478597
Mohammad Hasan Azad, Ramin Farzam, H. Sadeghi, Nikta Zarif Yussefian, M. Forouzanfar
Blood pressure’s oscillometric waveform (OMW) comprises several cardiovascular components such as cardiac activity, respiration-related changes, and Mayer wave that contribute to its total variability over time. Accurate modeling of the OMW as a function of these components and continuous tracking of their underlying parameters can provide insights into the cardiovascular system dynamics and help determine the role played by each component in blood pressure variability. This paper presents a new state-space model for the OMW consisting of different parameters such as cardiac and respiration frequencies, amplitudes, and phases. Since the dynamic state-space model of the OMW is highly nonlinear and dependent on a large number of parameters, we utilized the extended Kalman filter (EKF). Since the EKF accuracy is highly dependent on the parameter’s initial values, to obtain reasonable estimates of model initial values, a system identification procedure based on frequency domain analysis and curve-fitting was employed. The proposed method’s performance was analyzed on simulated data with and without the proposed system identification procedure. A mean absolute percentage error of 2.68% was achieved in estimating OMW when using the proposed system identification approach. The proposed approach shows promise toward beat-to-beat tracking of cardiovascular parameters in oscillometric devices.
血压的振荡波形(OMW)包括几个心血管成分,如心脏活动、呼吸相关变化和梅尔波,这些因素导致其随时间的总变异性。将OMW作为这些成分的函数进行精确建模,并持续跟踪其潜在参数,可以深入了解心血管系统动力学,并有助于确定每个成分在血压变异性中所起的作用。本文提出了一种由心率、呼吸频率、幅值和相位等不同参数组成的状态空间模型。由于OMW的动态状态空间模型是高度非线性的,并且依赖于大量的参数,我们使用了扩展卡尔曼滤波(EKF)。由于EKF精度高度依赖于参数的初值,为了获得合理的模型初值估计,采用了基于频域分析和曲线拟合的系统辨识程序。在模拟数据上对该方法的性能进行了分析。采用所提出的系统辨识方法估算OMW的平均绝对百分比误差为2.68%。所提出的方法显示了在振荡装置中对心血管参数进行搏动跟踪的希望。
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引用次数: 0
Contactless Continuous Monitoring Of Respiration 呼吸的非接触连续监测
Pub Date : 2021-06-23 DOI: 10.1109/MeMeA52024.2021.9478693
L. Scalise, M. Ali, L. Antognoli
Breathing is an important aspect of life. Monitoring of breathing signal plays an important role in clinical practice in order to determine the progression of illness. In this study the contactless modality to detect the breathing signal is assessed. For this purpose, the Laser Doppler Vibrometer (LDV) is used to detect the breathing signal. The test was performed on ten healthy volunteers and one simulator. An automatic algorithm is designed that can determine the efficiency of the contactless modality. The individuals were asked to simulate the conditions of apnea, tachypnea and bradypnea. The simulator was programmed with different respiratory rates in order to assess the functionality of the algorithm. The acquired signals were initially analyzed using manual setting of parameters and then using a standardised algorithm for every individual. The results were compared to determine the functionality. A user-friendly application was designed that allows user to set the ranges of high and low respiration rate along with the percentile value. The applications displays the pre-acquired breathing signal in real time scenarios along with the breathing tachograph and mean breathing rate. The difference between instantaneous respiration rates was found to be ±12.5% (mean value) in the case of signals acquired from human while in case of signal acquired from phantom simulator the same quantity was found to be ±1.6%.
呼吸是生命的一个重要方面。监测呼吸信号在临床实践中起着重要的作用,以确定疾病的进展。本研究对呼吸信号的非接触式检测方式进行了评估。为此,使用激光多普勒振动仪(LDV)来检测呼吸信号。该测试在10名健康志愿者和一个模拟器上进行。设计了一种自动算法来确定非接触式模式的效率。这些人被要求模拟呼吸暂停、呼吸急促和呼吸缓慢的情况。为了评估算法的功能,对模拟器进行了不同呼吸频率的编程。采集的信号首先通过手动设置参数进行分析,然后对每个个体使用标准化算法。将结果进行比较以确定其功能。设计了一个用户友好的应用程序,允许用户设置高和低呼吸速率的范围以及百分位数值。该应用程序在实时场景中显示预先获取的呼吸信号,以及呼吸记录仪和平均呼吸速率。实验结果表明,人体呼吸信号的瞬时呼吸速率差值为±12.5%(平均值),而模拟体呼吸信号的瞬时呼吸速率差值为±1.6%。
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引用次数: 2
Pressure sensors used as bioimpedance plantar electrodes: a feasibility study 压力传感器用作生物阻抗足底电极的可行性研究
Pub Date : 2021-06-23 DOI: 10.1109/MeMeA52024.2021.9478682
Isabel Morales, R. González-Landaeta, F. Simini
Diabetic Foot Ulcers are ominous consequence of Diabetic Foot. Only general preventive guidelines are available, and ulcers happen with no previous notice. To develop a multidimensional ulcer opening warning device: temperature, pressure, humidity and friction are usually considered. We use standard flexible Force Sensing Resistors FSR 402 to detect not only plantar pressure, but also plantar bioimpedance. Since FSR includes conductive electrodes covered by polymer films, the interface with the subject can be considered a capacitive electrode. A special bioimpedance detection circuit is required to inject current using two homologous FSR 402 contacts and measuring the resulting voltage from the other two contacts available. This circuit is able to detect the cardiac activity from the foot sole. For the first time, pressure sensors are used as bioimpedance electrodes.
糖尿病足溃疡是糖尿病足的不良后果。只有一般的预防指南可用,溃疡发生没有事先通知。开发多维度溃疡开口预警装置,通常要考虑温度、压力、湿度和摩擦等因素。我们使用标准的柔性力感电阻FSR 402不仅可以检测足底压力,还可以检测足底生物阻抗。由于FSR包括由聚合物薄膜覆盖的导电电极,因此与主体的界面可以被认为是电容电极。需要一种特殊的生物阻抗检测电路,使用两个同源FSR 402触点注入电流,并测量其他两个可用触点产生的电压。这个电路能够从脚底检测到心脏活动。压力传感器首次被用作生物阻抗电极。
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引用次数: 4
Efficient Compressive Sensing of Biomedical Signals Using A Permuted Kronecker-based Sparse Measurement Matrix 基于排列kronecker稀疏测量矩阵的生物医学信号有效压缩感知
Pub Date : 2021-06-23 DOI: 10.1109/MeMeA52024.2021.9478680
P. Firoozi, S. Rajan, I. Lambadaris
Compressive sensing (CS) is an innovative approach to simultaneously measure and compress signals such as biomedical signals that are sparse or compressible. A major effort in CS is to design a measurement matrix that can be used to encode and compress such signals. The measurement matrix structure has a direct impact on the computational and storage costs as well as the recovered signal quality. Sparse measurement matrices (i.e. with few non-zero elements) may drastically reduce these costs. We propose a permuted Kronecker-based sparse measurement matrix for sensing and data recovery in CS applications. In our study, we use three classes of sub-matrices (normalized Gaussian, Bernoulli, and BCH-based matrices) to create the proposed measurement matrix. Using ECG signals from the MIT-BIH Arrhythmia database, we show that the reconstructed signal quality is comparable to the ones achieved using well known CS methods. Our methodology results in an overall reduction in storage and computations, both during the sensing and recovery process. This approach can be generalized to other classes of eligible measurement matrices in CS.
压缩感知(CS)是一种同时测量和压缩稀疏或可压缩的生物医学信号的创新方法。CS的主要工作是设计一个测量矩阵,可以用来对这些信号进行编码和压缩。测量矩阵的结构直接影响到计算和存储成本以及恢复的信号质量。稀疏测量矩阵(即只有很少的非零元素)可以大大降低这些成本。我们提出了一种基于kronecker的稀疏测量矩阵,用于CS应用中的传感和数据恢复。在我们的研究中,我们使用三类子矩阵(归一化高斯矩阵、伯努利矩阵和基于bch的矩阵)来创建提议的测量矩阵。使用来自MIT-BIH心律失常数据库的心电信号,我们表明重建的信号质量与使用已知的CS方法获得的信号质量相当。在传感和恢复过程中,我们的方法总体上减少了存储和计算。这种方法可以推广到CS中其他类型的测量矩阵。
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引用次数: 0
Repeatability and reproducibility in the breathability measurement of surgical masks 医用口罩透气性测量的重复性和再现性
Pub Date : 2021-06-23 DOI: 10.1109/MeMeA52024.2021.9478732
Juri Taborri, Beatrice Stocchi, G. Calabrò, S. Rossi
The pandemic COVID-19 is still requiring several countermeasures to adopted in order to decrease the virus spread. Among others, face masks have shown their potentiality to reduce the person-to-person transmission. For this reason, several research groups and/or industries focused their supply chain in the production of innovative materials for the face mask design. Considering the surgical mask, several parameters have to be checked before their commercialization, as for example the breathability. This study aims at evaluating the repeatability and reproducibility of the breathability measurement in surgical masks, and at assessing the effects induced by the selected measurement points on the mask. Three samples for each type I, II and IIR masks were tested within the experimental protocol. Breathability was measured by following the UNI EN 14683:2019. Fifteen measurement points were identified for each mask and the measure was repeated five times per each point. Standard deviation across the repeated measures on the single point and across the different tested areas were used to evaluate the repeatability and reproducibility of the procedure, respectively. The measurement uncertainty was also computed. In addition, in order to verify the effects induced by the selection of five points out the available fifteen, as requested by the UNI EN 14683:2019, all combinations of points were tested. Results showed a high value of reproducibility error, leading to the consideration that different areas of the same mask are characterized by different values of breathability. Thus, the selection of the five measurement points to perform the breathability measurement according to the standard is a crucial aspect that can influence the result of mask compliance. The results of the present paper could provide useful information for the standardization of the breathability measurement.
COVID-19大流行仍需要采取若干对策,以减少病毒传播。除其他外,口罩已显示出减少人际传播的潜力。出于这个原因,一些研究小组和/或行业将其供应链重点放在生产用于口罩设计的创新材料上。考虑到外科口罩,在其商业化之前必须检查几个参数,例如透气性。本研究旨在评估外科口罩透气性测量的可重复性和再现性,并评估所选测点对口罩的影响。根据实验方案对I型、II型和IIR型口罩各3个样本进行检测。透气性按照UNI EN 14683:2019进行测量。每个掩模确定15个测量点,每个测量点重复测量5次。在单点和不同测试区域重复测量的标准偏差分别用于评估该程序的重复性和再现性。计算了测量不确定度。此外,根据UNI EN 14683:2019的要求,为了验证从可用的15个点中选择5个点所引起的效果,对所有点的组合进行了测试。结果显示重复性误差值较高,导致考虑到同一口罩的不同区域具有不同的透气性值。因此,根据标准选择五个测点进行透气性测量是影响口罩符合性结果的关键方面。本文的研究结果可为透气性测量的标准化提供参考。
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引用次数: 6
Preliminary Study of a Flexible Printed Multi-Sensing Platform for Electromyography and Lactate Measuring during Rehabilitation 一种用于康复过程中肌电和乳酸测量的柔性印刷多传感平台的初步研究
Pub Date : 2021-06-23 DOI: 10.1109/MeMeA52024.2021.9478729
Sarah Tonello, G. Giorgi, C. Narduzzi, Tiziano Fapanni, Edoardo Cantù, M. Serpelloni, E. Sardini, S. Carrara
Real-time measure of muscular fatigue during physical exercise is highly demanded in fields as rehabilitation and physiotherapy, both hospital and home-based. In addition to the well-accepted features extracted from EMG measurements, an increasing interest has been recently addressed to the investigation of biochemical fatigue markers to drive additional information on fatigue evolution. We propose here a multi-sensing non-invasive approach to measure fatigue through EMG and lactate sensing. A printed unobtrusive sensing patch was developed as first prototype by means of the emerging Aerosol Jet Printing technique, ensuring high repeatability and stability even on a flexible substrate. To study the behavior of this patch, preliminary measurements were acquired to perform an analysis of both the printed sensors. EMG electrodes, with skin-electrodes impedance magnitude and phase angle with trends comparable to commercial electrodes, showed the possibility to successfully extract mean and median frequencies from EMG and to detect their decrease after intense exercise. Preliminary results on lactate static measure showed a limit of detection of 3.1±0.3 mM with the highest linearity (R=0.9995) and sensitivity (0.39 µA/mM) in the range 0-20 mM. Furthermore, dynamic tests permitted a preliminary analysis on the ability of the sensor to measure changes in the concentration of lactate continuously. Overall, reported measures represent a promising starting point to develop a patch easily integrable in any wearable for noninvasive and totally customized fatigue measure during physical exercise.
在康复和物理治疗领域,无论是医院还是家庭,对体育锻炼期间肌肉疲劳的实时测量都有很高的要求。除了从肌电图测量中提取的被广泛接受的特征外,最近人们对疲劳生化标记物的研究越来越感兴趣,以推动疲劳演变的更多信息。我们在这里提出了一种多传感的非侵入性方法,通过肌电图和乳酸传感来测量疲劳。通过新兴的气溶胶喷射打印技术,开发了一个印刷的不显眼的传感贴片作为第一个原型,即使在柔性基板上也能确保高重复性和稳定性。为了研究该贴片的行为,对两个印刷传感器进行了初步测量分析。肌电图电极的皮肤电极阻抗幅度和相位角与商业电极的趋势相当,表明有可能成功地从肌电图中提取平均和中位数频率,并检测到剧烈运动后它们的下降。乳酸静态测量的初步结果显示,在0-20 mM范围内,检测限为3.1±0.3 mM,线性度最高(R=0.9995),灵敏度为0.39µa /mM。此外,动态测试允许对传感器连续测量乳酸浓度变化的能力进行初步分析。总的来说,报告的测量方法代表了一个有希望的起点,即开发一种易于集成在任何可穿戴设备上的贴片,用于体育锻炼期间的非侵入性和完全定制的疲劳测量。
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引用次数: 5
Reliability of kinematic parameters related to the Timed Up and Go Test in patients with gait impairments 与步态障碍患者的Timed Up and Go测试相关的运动学参数的可靠性
Pub Date : 2021-06-23 DOI: 10.1109/MeMeA52024.2021.9478762
G. Pagano, L. Donisi, V. Marsico, E. Losavio, M. Cesarelli, G. D'Addio
Pathologies which imply motor impairment are most common and very studied. The aim of the study is to explore the repeatability of kinematic parameters related to the Timed Up and Go test in different pathologies: hemiparesis, femur fracture, hip replacement and knee replacement. We performed the study instrumenting the patients with a commercial wearable inertial system for gait analysis: G-WALK System by BTS Bioengineering Inc. A cohort of 40 patients with neurological and orthopedic pathologies was enrolled in the study. Repeatability was assessed through the calculation of the Intraclass Correlation Coefficient. Study results showed that the motion parameters exhibited different repeatability. Moreover their repeatability changed on the basis of the kind of pathology under examination. The study demonstrated the importance of a repeatability study to be a valuable approach to select the kinematic parameters which are be able to better characterize a specific pathology and consequently the rehabilitation outcome of patients. The future investigations on enriched datasets will further confirm these preliminary results.
暗示运动障碍的病理是最常见的,并且被研究得非常多。本研究的目的是探讨与Timed Up and Go测试相关的运动学参数在不同病理情况下的重复性:半身不瘫、股骨骨折、髋关节置换术和膝关节置换术。我们使用BTS生物工程公司的商用可穿戴惯性系统G-WALK系统对患者进行步态分析。该研究纳入了40名患有神经和骨科疾病的患者。通过计算类内相关系数评估重复性。研究结果表明,运动参数具有不同的重复性。此外,它们的重复性根据所检查的病理类型而变化。该研究证明了可重复性研究的重要性,它是选择运动学参数的一种有价值的方法,能够更好地表征特定病理,从而确定患者的康复结果。未来对丰富数据集的调查将进一步证实这些初步结果。
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引用次数: 1
Dynamic Shear and Normal Forces on Patient Skin in Sling Lift Transfers 动态剪切力和法向力对患者皮肤在吊带提升转移
Pub Date : 2021-06-23 DOI: 10.1109/MeMeA52024.2021.9478758
Steven Cramp, Bruce Wallace
The sling lift transfer system is commonly used in hospital and care home settings to transfer immobile and limited mobility patients from bed to chair or gurney. Even though this is the current standard of care, injuries to patients because of the forces applied to skin by the lift occur frequently. The lifts cause both normal and shear forces on the skin, and previous studies have only measured and reported on the applied normal forces with no assessment of shear. In this work, we use a novel shear and normal force sensor designed specifically to assess forces on skin and report the dynamic normal and shear forces during a sling lift. The shear forces are shown to be up to 8N for a partial lift of an adult male and occur both laterally and longitudinally along the thigh. Shear forces pull the skin and can cause injury, especially as skin tends to thin with age and become more susceptible to damage. This is the first reporting of shear forces during patient lifts.
吊带升降转移系统通常用于医院和养老院设置转移不动和行动不便的病人从床到椅子或轮床。尽管这是目前的护理标准,但由于升降机施加在皮肤上的力而对患者造成的伤害经常发生。抬升会对皮肤产生法向力和剪切力,以前的研究只测量和报告了施加的法向力,而没有评估剪切力。在这项工作中,我们使用了一种新型的剪切力和法向力传感器,专门用于评估皮肤上的力,并报告吊索提升过程中的动态法向力和剪力。对于一个成年男性的部分抬升,剪切力显示为高达8N,并沿大腿横向和纵向发生。剪切力拉扯皮肤,可能会造成伤害,尤其是随着年龄的增长,皮肤往往会变薄,更容易受到损伤。这是第一次报道在病人抬举过程中剪切力。
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引用次数: 4
Autonomic Nervous System Assessment During Physical Rehabilitation Serious Game 自主神经系统评估在物理康复严重游戏
Pub Date : 2021-06-23 DOI: 10.1109/MeMeA52024.2021.9478742
M. Rodrigues, O. Postolache, F. Cercas
This study is aimed to analyze the correlations between heart rate variability (HRV) and a virtual reality (VR) serious game for physical rehabilitation. The possibility to use serious exergames as tools of ambient assisted living to promote physical activities during the COVID-19 pandemic lock-down period is considered appropriate to enhance patients’ engagement in physical rehabilitation exercises performed at home. The analyzed data in this study provides HRV information collected from a small group of healthy volunteers that participated in two gameplay sessions of the VR serious exergame. Two levels of difficulty were considered. HRV parameters were calculated from the analysis of electrocardiograms (ECG) for an imposed protocol characterized by three different periods (rest, play and rest) The HRV analysis was based on time-domain and frequency-domain methods and the experimental results showed significant changes associated with different game sessions. Higher values of HF components and RMSSD were obtained for a less physical demanding gameplay session, whereas the predominance of LF components was observed for the game session with high level of difficulty. These findings suggested that this serious game had an important impact on both physical and cognitive stimulation, and therefore its implementation in home-based assisted environments can help increase weekly performance of physical activity, enhance balance and limbs mobility, help to reduce anxiety levels, and maintain high levels of HRV.
本研究旨在分析心率变异性(HRV)与虚拟现实(VR)物理康复严肃游戏的相关性。在COVID-19大流行封锁期间,将严肃运动游戏作为环境辅助生活工具来促进身体活动的可能性被认为是适当的,以提高患者参与在家进行的身体康复锻炼。本研究分析的数据提供了从一小群健康志愿者中收集的HRV信息,这些志愿者参加了两个VR严肃游戏的游戏环节。我们考虑了两个难度等级。HRV参数通过对三个不同时段(休息、游戏和休息)的心电图分析计算,HRV分析基于时域和频域方法,实验结果显示不同游戏时段的HRV参数有显著变化。在体力要求较低的游戏过程中,高频成分和RMSSD的值较高,而在高难度的游戏过程中,观察到低频成分的优势。这些研究结果表明,这种严肃的游戏对身体和认知刺激都有重要影响,因此在家庭辅助环境中实施它可以帮助增加每周的身体活动表现,增强平衡和四肢活动能力,帮助减少焦虑水平,并保持高水平的HRV。
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引用次数: 1
期刊
2021 IEEE International Symposium on Medical Measurements and Applications (MeMeA)
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