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2021 IEEE International Symposium on Medical Measurements and Applications (MeMeA)最新文献

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Image Quality Assessment for Endoscopy Applications 内窥镜应用的图像质量评估
Pub Date : 2021-06-23 DOI: 10.1109/MeMeA52024.2021.9478603
R. Nishitha, Amalan Sebastin, Shubham Sharma, Ajay Kumar Gurrala, P. PreejithS., J. Joseph, M. Sivaprakasam
Assessment of image quality parameters in medical applications is crucial to produce high quality images that would significantly improve diagnoses and therapies. Solutions available in the market to assess the image quality provide experimental setups, standard test charts, and illumination setups. Parameters like sharpness, geometric distortion, and dynamic range require separate test charts and therefore can only be measured one at a time. In this paper, a single test chart to measure most of the image quality parameters has been described. A single image of this test chart could provide assessment of all the parameters considered. The size of the test chart could be customized according to the endoscopy application. An experimental setup was also designed in-house. This approach helped in developing a comprehensive and inexpensive assessment technique complying with the International Organization of Standardization (ISO) standards. Currently, the algorithms work with still images and could be extended to assess how the measured parameters would vary on a live video stream.
医学应用中图像质量参数的评估对于产生高质量的图像至关重要,这将显著改善诊断和治疗。市场上可用的评估图像质量的解决方案提供了实验设置、标准测试图表和照明设置。像清晰度、几何失真和动态范围这样的参数需要单独的测试图表,因此一次只能测量一个。在本文中,描述了一个单一的测试图来测量大多数图像质量参数。该测试图的单个图像可以提供所考虑的所有参数的评估。测试图的大小可以根据内窥镜的应用定制。内部还设计了一个实验装置。这种方法有助于开发一种符合国际标准化组织(ISO)标准的全面而廉价的评估技术。目前,该算法适用于静态图像,并可以扩展到评估实时视频流中测量参数的变化情况。
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引用次数: 4
Repeatability and reproducibility in the breathability measurement of surgical masks 医用口罩透气性测量的重复性和再现性
Pub Date : 2021-06-23 DOI: 10.1109/MeMeA52024.2021.9478732
Juri Taborri, Beatrice Stocchi, G. Calabrò, S. Rossi
The pandemic COVID-19 is still requiring several countermeasures to adopted in order to decrease the virus spread. Among others, face masks have shown their potentiality to reduce the person-to-person transmission. For this reason, several research groups and/or industries focused their supply chain in the production of innovative materials for the face mask design. Considering the surgical mask, several parameters have to be checked before their commercialization, as for example the breathability. This study aims at evaluating the repeatability and reproducibility of the breathability measurement in surgical masks, and at assessing the effects induced by the selected measurement points on the mask. Three samples for each type I, II and IIR masks were tested within the experimental protocol. Breathability was measured by following the UNI EN 14683:2019. Fifteen measurement points were identified for each mask and the measure was repeated five times per each point. Standard deviation across the repeated measures on the single point and across the different tested areas were used to evaluate the repeatability and reproducibility of the procedure, respectively. The measurement uncertainty was also computed. In addition, in order to verify the effects induced by the selection of five points out the available fifteen, as requested by the UNI EN 14683:2019, all combinations of points were tested. Results showed a high value of reproducibility error, leading to the consideration that different areas of the same mask are characterized by different values of breathability. Thus, the selection of the five measurement points to perform the breathability measurement according to the standard is a crucial aspect that can influence the result of mask compliance. The results of the present paper could provide useful information for the standardization of the breathability measurement.
COVID-19大流行仍需要采取若干对策,以减少病毒传播。除其他外,口罩已显示出减少人际传播的潜力。出于这个原因,一些研究小组和/或行业将其供应链重点放在生产用于口罩设计的创新材料上。考虑到外科口罩,在其商业化之前必须检查几个参数,例如透气性。本研究旨在评估外科口罩透气性测量的可重复性和再现性,并评估所选测点对口罩的影响。根据实验方案对I型、II型和IIR型口罩各3个样本进行检测。透气性按照UNI EN 14683:2019进行测量。每个掩模确定15个测量点,每个测量点重复测量5次。在单点和不同测试区域重复测量的标准偏差分别用于评估该程序的重复性和再现性。计算了测量不确定度。此外,根据UNI EN 14683:2019的要求,为了验证从可用的15个点中选择5个点所引起的效果,对所有点的组合进行了测试。结果显示重复性误差值较高,导致考虑到同一口罩的不同区域具有不同的透气性值。因此,根据标准选择五个测点进行透气性测量是影响口罩符合性结果的关键方面。本文的研究结果可为透气性测量的标准化提供参考。
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引用次数: 6
Preliminary Study of a Flexible Printed Multi-Sensing Platform for Electromyography and Lactate Measuring during Rehabilitation 一种用于康复过程中肌电和乳酸测量的柔性印刷多传感平台的初步研究
Pub Date : 2021-06-23 DOI: 10.1109/MeMeA52024.2021.9478729
Sarah Tonello, G. Giorgi, C. Narduzzi, Tiziano Fapanni, Edoardo Cantù, M. Serpelloni, E. Sardini, S. Carrara
Real-time measure of muscular fatigue during physical exercise is highly demanded in fields as rehabilitation and physiotherapy, both hospital and home-based. In addition to the well-accepted features extracted from EMG measurements, an increasing interest has been recently addressed to the investigation of biochemical fatigue markers to drive additional information on fatigue evolution. We propose here a multi-sensing non-invasive approach to measure fatigue through EMG and lactate sensing. A printed unobtrusive sensing patch was developed as first prototype by means of the emerging Aerosol Jet Printing technique, ensuring high repeatability and stability even on a flexible substrate. To study the behavior of this patch, preliminary measurements were acquired to perform an analysis of both the printed sensors. EMG electrodes, with skin-electrodes impedance magnitude and phase angle with trends comparable to commercial electrodes, showed the possibility to successfully extract mean and median frequencies from EMG and to detect their decrease after intense exercise. Preliminary results on lactate static measure showed a limit of detection of 3.1±0.3 mM with the highest linearity (R=0.9995) and sensitivity (0.39 µA/mM) in the range 0-20 mM. Furthermore, dynamic tests permitted a preliminary analysis on the ability of the sensor to measure changes in the concentration of lactate continuously. Overall, reported measures represent a promising starting point to develop a patch easily integrable in any wearable for noninvasive and totally customized fatigue measure during physical exercise.
在康复和物理治疗领域,无论是医院还是家庭,对体育锻炼期间肌肉疲劳的实时测量都有很高的要求。除了从肌电图测量中提取的被广泛接受的特征外,最近人们对疲劳生化标记物的研究越来越感兴趣,以推动疲劳演变的更多信息。我们在这里提出了一种多传感的非侵入性方法,通过肌电图和乳酸传感来测量疲劳。通过新兴的气溶胶喷射打印技术,开发了一个印刷的不显眼的传感贴片作为第一个原型,即使在柔性基板上也能确保高重复性和稳定性。为了研究该贴片的行为,对两个印刷传感器进行了初步测量分析。肌电图电极的皮肤电极阻抗幅度和相位角与商业电极的趋势相当,表明有可能成功地从肌电图中提取平均和中位数频率,并检测到剧烈运动后它们的下降。乳酸静态测量的初步结果显示,在0-20 mM范围内,检测限为3.1±0.3 mM,线性度最高(R=0.9995),灵敏度为0.39µa /mM。此外,动态测试允许对传感器连续测量乳酸浓度变化的能力进行初步分析。总的来说,报告的测量方法代表了一个有希望的起点,即开发一种易于集成在任何可穿戴设备上的贴片,用于体育锻炼期间的非侵入性和完全定制的疲劳测量。
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引用次数: 5
The capabilities of bioelectrical impedance body composition monitors in determining metabolic parameters during body shaping 生物电阻抗身体成分监测仪在身体塑形过程中测定代谢参数的能力
Pub Date : 2021-06-23 DOI: 10.1109/MeMeA52024.2021.9478755
N. I. Khramtsova, S. Plaksin, D. N. Ponomarev, A. Sotskov
Body composition is closely related to the metabolic and biological functions of the body. Body composition and metabolic parameters were determined in 48 healthy women without an obesity, which underwent body shaping procedure – liposuction, with a usage of two types of body composition monitors.After liposuction, body weight significantly increased on average by 0.5 - 1.0 kg (p = 0.001). Body weight and body mass index correlated with all metabolic parameters.Body type was automatically calculated by "Tanita BC-542". Determination of body type when using "Tanita BC-601" was done manually. More than half of the patients on admission had a standard body type ("5" type) - 20 (54%), in 15 (41%) "hidden obesity" was found. After liposuction, 4 (14%) women improved their body type.The level of basal metabolic rate (BMR) in patients initially averaged 1340 ± 96 kcal when measured using a two-electrode analyzer, and 2128 ± 81 kcal - using a four-electrode analyzer (p = 0.0001), according to the literature – about 1000-1200 kcal. The average increase in BMR immediately after liposuction was 21 kcal, on the 7th day - 32 kcal.The metabolic age after body contouring became less than the actual one in 10 (56%) patients, by an average of 3.1 years (p = 0.0007).Four-electrode monitor revealed that an average decrease of fat on the abdomen was 5.4%. However, a decrease in its content in the hands and legs (in those zones that remained intact) was also detected. The analyzer also determined an increase in the content of muscles on the abdomen.In general, the bioelectrical impedance measurement in analysis of metabolic parameters in dynamics is simple and accessible, it has also a clinical importance. However, due to the identification of some errors, it requires repeated measurements and further improvement.
机体成分与机体的代谢和生物功能密切相关。对48名没有肥胖的健康女性进行了身体塑形手术——抽脂,并使用两种类型的身体成分监测仪,测定了她们的身体成分和代谢参数。吸脂后体重平均增加0.5 ~ 1.0 kg (p = 0.001)。体重和体质指数与所有代谢参数相关。体型由“Tanita BC-542”自动计算。使用“Tanita BC-601”时,机体类型的确定是手工完成的。超过一半的入院患者具有标准体型(“5”型)- 20 (54%),15 (41%)“隐性肥胖”被发现。抽脂后,4名(14%)女性的体型得到改善。水平的基础代谢率(BMR)最初的病人平均1340±96千卡使用二电极测量分析仪时,使用四电极和2128±81千卡,分析仪(p = 0.0001),根据文献——大约1000 - 1200千卡。平均抽脂后立即增加基础代谢率是21千卡,7天——32岁kcal.The代谢后的身体轮廓变得比实际的少10个(56%)病人,平均3.1年(p = 0.0007)。四电极监测显示腹部脂肪平均减少5.4%。然而,手和腿(在那些完好无损的区域)的含量也有所减少。分析仪还测定了腹部肌肉含量的增加。总的来说,生物电阻抗测量在动态代谢参数分析中简单易行,具有临床应用价值。但由于存在一些误差,需要反复测量和进一步改进。
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引用次数: 0
Pressure sensors used as bioimpedance plantar electrodes: a feasibility study 压力传感器用作生物阻抗足底电极的可行性研究
Pub Date : 2021-06-23 DOI: 10.1109/MeMeA52024.2021.9478682
Isabel Morales, R. González-Landaeta, F. Simini
Diabetic Foot Ulcers are ominous consequence of Diabetic Foot. Only general preventive guidelines are available, and ulcers happen with no previous notice. To develop a multidimensional ulcer opening warning device: temperature, pressure, humidity and friction are usually considered. We use standard flexible Force Sensing Resistors FSR 402 to detect not only plantar pressure, but also plantar bioimpedance. Since FSR includes conductive electrodes covered by polymer films, the interface with the subject can be considered a capacitive electrode. A special bioimpedance detection circuit is required to inject current using two homologous FSR 402 contacts and measuring the resulting voltage from the other two contacts available. This circuit is able to detect the cardiac activity from the foot sole. For the first time, pressure sensors are used as bioimpedance electrodes.
糖尿病足溃疡是糖尿病足的不良后果。只有一般的预防指南可用,溃疡发生没有事先通知。开发多维度溃疡开口预警装置,通常要考虑温度、压力、湿度和摩擦等因素。我们使用标准的柔性力感电阻FSR 402不仅可以检测足底压力,还可以检测足底生物阻抗。由于FSR包括由聚合物薄膜覆盖的导电电极,因此与主体的界面可以被认为是电容电极。需要一种特殊的生物阻抗检测电路,使用两个同源FSR 402触点注入电流,并测量其他两个可用触点产生的电压。这个电路能够从脚底检测到心脏活动。压力传感器首次被用作生物阻抗电极。
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引用次数: 4
Innovative Smart Face Mask to Protect Workers from COVID-19 Infection 创新智能口罩,保护工人免受COVID-19感染
Pub Date : 2021-06-23 DOI: 10.1109/MeMeA52024.2021.9478739
A. Fois, F. Tocco, A. Dell'Osa, Laura Melis, Ugo Bertelli, A. Concu, A. M. Bertetto, Carmen Serra
The most frequent prodromes of COVID-19 infection are fever and signs/symptoms of incipient respiratory diseases such as cough and shortness of breath or tachypnea. However, it is not infrequent that in patients infected with COVID-19, in addition to respiratory manifestations, cardiac rhythm alterations are also present which can be an early sign of an acute cardiovascular syndrome. It is therefore of utmost importance, especially for health care and civil protection workers who are most exposed to the infection, to detect the prodromal symptoms of this infection in order to be able to make a diagnosis of possible positivity to COVID-19 infection as quickly as possible and therefore to provide their immediate insertion in the isolation/therapy protocols. Here a prototype of a smart face mask is presented: the AG47-SmartMask. In addition to having the function of both an active and passive anti COVID-19 filter, the latter by an electro-heated filter brought to a minimum temperature of 38°C, the AG47-SmartMask also allows the continuous monitoring of numerous cardio-pulmonary variables. Several specific sensors are incorporated into the mask in an original way that assess the inside mask temperature, relative humidity and air pressure together with the auricular assessment of body temperature, heart rate and percentage of oxygen saturation of haemoglobin. Sensors work in synergy with an advanced telemedicine platform. To validate the device, twenty workers engaged in a vegetable packaging chain tested the tool simulating, while working, both tachypnea and cough, and the AG47-SmartMask faithfully quantified the simulated dyspnoic events.
COVID-19感染最常见的前驱症状是发烧和早期呼吸道疾病的体征/症状,如咳嗽、呼吸短促或呼吸急促。然而,在感染COVID-19的患者中,除了呼吸症状外,心律改变也很常见,这可能是急性心血管综合征的早期征兆。因此,至关重要的是,特别是对最容易感染的卫生保健和民防工作人员来说,检测这种感染的前驱症状,以便能够尽快诊断出COVID-19感染可能呈阳性,从而立即将其纳入隔离/治疗方案。这里介绍了一种智能口罩的原型:AG47-SmartMask。除了具有主动和被动抗COVID-19过滤器的功能(后者通过电热过滤器达到最低温度38°C)外,AG47-SmartMask还可以连续监测许多心肺变量。几个特定的传感器以一种原始的方式集成到口罩中,评估口罩内的温度、相对湿度和气压,以及耳部对体温、心率和血红蛋白氧饱和度的评估。传感器与先进的远程医疗平台协同工作。为了验证该设备,20名从事蔬菜包装链的工人在工作时测试了该工具模拟呼吸急促和咳嗽,AG47-SmartMask忠实地量化了模拟的呼吸困难事件。
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引用次数: 8
Toward Continuous Estimation of Cardiorespiratory Parameters in Oscillometry: A Simulation Study 振荡测量法中心肺参数的连续估计:模拟研究
Pub Date : 2021-06-23 DOI: 10.1109/MeMeA52024.2021.9478597
Mohammad Hasan Azad, Ramin Farzam, H. Sadeghi, Nikta Zarif Yussefian, M. Forouzanfar
Blood pressure’s oscillometric waveform (OMW) comprises several cardiovascular components such as cardiac activity, respiration-related changes, and Mayer wave that contribute to its total variability over time. Accurate modeling of the OMW as a function of these components and continuous tracking of their underlying parameters can provide insights into the cardiovascular system dynamics and help determine the role played by each component in blood pressure variability. This paper presents a new state-space model for the OMW consisting of different parameters such as cardiac and respiration frequencies, amplitudes, and phases. Since the dynamic state-space model of the OMW is highly nonlinear and dependent on a large number of parameters, we utilized the extended Kalman filter (EKF). Since the EKF accuracy is highly dependent on the parameter’s initial values, to obtain reasonable estimates of model initial values, a system identification procedure based on frequency domain analysis and curve-fitting was employed. The proposed method’s performance was analyzed on simulated data with and without the proposed system identification procedure. A mean absolute percentage error of 2.68% was achieved in estimating OMW when using the proposed system identification approach. The proposed approach shows promise toward beat-to-beat tracking of cardiovascular parameters in oscillometric devices.
血压的振荡波形(OMW)包括几个心血管成分,如心脏活动、呼吸相关变化和梅尔波,这些因素导致其随时间的总变异性。将OMW作为这些成分的函数进行精确建模,并持续跟踪其潜在参数,可以深入了解心血管系统动力学,并有助于确定每个成分在血压变异性中所起的作用。本文提出了一种由心率、呼吸频率、幅值和相位等不同参数组成的状态空间模型。由于OMW的动态状态空间模型是高度非线性的,并且依赖于大量的参数,我们使用了扩展卡尔曼滤波(EKF)。由于EKF精度高度依赖于参数的初值,为了获得合理的模型初值估计,采用了基于频域分析和曲线拟合的系统辨识程序。在模拟数据上对该方法的性能进行了分析。采用所提出的系统辨识方法估算OMW的平均绝对百分比误差为2.68%。所提出的方法显示了在振荡装置中对心血管参数进行搏动跟踪的希望。
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引用次数: 0
Reliability of kinematic parameters related to the Timed Up and Go Test in patients with gait impairments 与步态障碍患者的Timed Up and Go测试相关的运动学参数的可靠性
Pub Date : 2021-06-23 DOI: 10.1109/MeMeA52024.2021.9478762
G. Pagano, L. Donisi, V. Marsico, E. Losavio, M. Cesarelli, G. D'Addio
Pathologies which imply motor impairment are most common and very studied. The aim of the study is to explore the repeatability of kinematic parameters related to the Timed Up and Go test in different pathologies: hemiparesis, femur fracture, hip replacement and knee replacement. We performed the study instrumenting the patients with a commercial wearable inertial system for gait analysis: G-WALK System by BTS Bioengineering Inc. A cohort of 40 patients with neurological and orthopedic pathologies was enrolled in the study. Repeatability was assessed through the calculation of the Intraclass Correlation Coefficient. Study results showed that the motion parameters exhibited different repeatability. Moreover their repeatability changed on the basis of the kind of pathology under examination. The study demonstrated the importance of a repeatability study to be a valuable approach to select the kinematic parameters which are be able to better characterize a specific pathology and consequently the rehabilitation outcome of patients. The future investigations on enriched datasets will further confirm these preliminary results.
暗示运动障碍的病理是最常见的,并且被研究得非常多。本研究的目的是探讨与Timed Up and Go测试相关的运动学参数在不同病理情况下的重复性:半身不瘫、股骨骨折、髋关节置换术和膝关节置换术。我们使用BTS生物工程公司的商用可穿戴惯性系统G-WALK系统对患者进行步态分析。该研究纳入了40名患有神经和骨科疾病的患者。通过计算类内相关系数评估重复性。研究结果表明,运动参数具有不同的重复性。此外,它们的重复性根据所检查的病理类型而变化。该研究证明了可重复性研究的重要性,它是选择运动学参数的一种有价值的方法,能够更好地表征特定病理,从而确定患者的康复结果。未来对丰富数据集的调查将进一步证实这些初步结果。
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引用次数: 1
Measuring the Effect of Rhythmic Auditory Stimuli on Parkinsonian Gait in Challenging Settings 测量节奏性听觉刺激在挑战性环境下对帕金森步态的影响
Pub Date : 2021-06-23 DOI: 10.1109/MeMeA52024.2021.9478771
Ilaria Mileti, M. Germanotta, C. Iacovelli, G. D. Lazzaro, Z. Prete, M. Monaco, D. Ricciardi, A. Bentivoglio, E. Palermo
Rhythmic auditory stimuli (RAS) improve the disabling motor symptom of Parkinson’s disease patients. In the large majority of studies, the effect of RAS has been assessed during common activities such as walking and turning. However, how RAS modulates parkinsonian behaviors in more challenging settings of daily living and whether a machine learning algorithm could classify them remains unclear. Eleven patients with idiopathic PD (age 72±7 years) were asked to walk under four conditions: straight walking, walking over an irregular surface, walking within a narrow pathway, and walking along a curving path (eight-shaped), with and without external stimulation. RAS pace was set at 110% of the normal cadence and spatio-temporal gait parameters were measured through two inertial measurement units placed on feet. k-Nearest Neighbor (k-NN) algorithm, with and without principal component analysis (PCA) as feature selector, was used for the classification of walking conditions. Cadence, gait speed, and gait time improved during RAS walking, regardless of challenging walking conditions. On the contrary, stride length increased only in straight walking, while gait speed showed improvement also in walking over an irregular surface and walking within narrow pathway conditions. k-NN algorithm reported higher accuracy (72.4%) in the classification of eight- shaped curving path both considering the overall feature set and a reduced one. These results open to the possibility of measuring RAS-induced effects on PD mobility in an ecological scenario and improving their administration based on the actual motor activity.
节律性听觉刺激(RAS)改善帕金森病患者的运动失能症状。在大多数研究中,RAS的作用已经在诸如走路和转身等常见活动中进行了评估。然而,RAS如何在更具挑战性的日常生活环境中调节帕金森病的行为,以及机器学习算法是否可以对它们进行分类,目前尚不清楚。11例特发性PD患者(年龄72±7岁)被要求在四种条件下行走:直线行走、不规则表面行走、狭窄路径行走、弯曲路径行走(8形),有和没有外部刺激。将RAS步速设定为正常步速的110%,通过放置在足部的两个惯性测量单元测量时空步态参数。采用k-最近邻(k-NN)算法,分别以主成分分析(PCA)和不以主成分分析(PCA)为特征选择器对行走状态进行分类。在RAS步行期间,步频、步态速度和步态时间都有所改善,无论步行条件如何。相反,只有在直线行走时,步幅才会增加,而在不规则路面上行走和在狭窄通道条件下行走时,步态速度也会有所改善。k-NN算法在考虑整体特征集和简化特征集的情况下,对八形曲线路径的分类准确率均达到72.4%。这些结果为在生态环境下测量ras诱导的PD运动能力影响以及根据实际运动活动改善其管理提供了可能性。
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引用次数: 0
[Front matter] (前页)
Pub Date : 2021-06-23 DOI: 10.1109/memea52024.2021.9478705
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引用次数: 0
期刊
2021 IEEE International Symposium on Medical Measurements and Applications (MeMeA)
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